3VJAA

Crystal structure of the human squalene synthase
Total Genus 143
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
143
sequence length
335
structure length
335
Chain Sequence
SLSSSLKTCYKYLNQTSRSFAAVIQALDGEMRNAVCIFYLVLRALDTLEDDMTISVEKKVPLLHNFHSFLYQPDWRFMESKEKDRQVLEDFPTISLEFRNLAEKYQTVIADICRRMGIGMAEFLDKHVTSEQEWDKYCHYVAGLVGIGLSRLFSASEFEDPLVGEDTERANSMGLFLQKTNIIRDYLEDQQGGREFWPQEVWSRYVKKLGDFAKPENIDLAVQCLNELITNALHHIPDVITYLSRLRNQSVFNFCAIPQVMAIATLAACYNNQQVFKGAVKIRKGQAVTLMMDATNMPAVKAIIYQYMEEIYHRIPDSDPSSSKTRQIISTIRTQ
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Binding modes of zaragozic acid A to human squalene synthase and staphylococcal dehydrosqualene synthase
pubmed doi rcsb
molecule tags Transferase
source organism Homo sapiens
molecule keywords Squalene synthase
total genus 143
structure length 335
sequence length 335
chains with identical sequence B
ec nomenclature ec 2.5.1.21: Squalene synthase.
pdb deposition date 2011-10-14

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00494 SQS_PSY Squalene/phytoene synthase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.600.10 Mainly Alpha Orthogonal Bundle Farnesyl Diphosphate Synthase Farnesyl Diphosphate Synthase 3vjaA00
3IPIA 3SDTA 2FTZA 1UBWA 4P0XA 5DZ2A 3NF2A 5IM1A 2Z7IA 3N46F 5HN9A 4LIXA 4F6XA 3BNYA 1WL3A 5A0JA 3OACB 1YHKA 5IK0A 2Z4WA 3LVSA 4DI5A 3WSAA 2Q9ZA 3KRFB 5B00A 2E4OA 3N1VF 3KROB 4KVDA 3P5PA 4DZWA 3V66A 2E8VA 1V4KA 4PVXF 3N3DA 2PS6A 3LMDA 3WCMA 5B0LA 4LTZA 3NPKA 3NRIA 1WMWA 4KVWA 1VG3A 4NFIF 2ONHA 3WCJA 3WCEA 4L2XF 2E8XA 3EZ3A 4LFEA 4FP4A 5IN8A 5DGMF 3QKCA 3WCIA 5B0MA 3KRCA 1PS1A 3WCLA 1EZFA 3LK5A 2F8ZF 4GP1A 3AQCB 3PKOA 4UMJA 2ZY1A 3N6KF 3SAEA 3OABA 4DHDA 3PYAA 4LFGA 2E95A 4GAXA 5DGSF 5B0IA 5DHIA 2ZEUA 4E9UA 5EROA 5EASA 4H5DF 3ADZA 3AQBB 4NFKF 5B0KA 5IK6A 2Z52A 4GA3A 3V1VA 4JVJF 3NPRA 4KKMA 2E8TA 3N0GA 5E8KA 4EA2A 4FJQA 1N21A 4H5CF 1YV5A 4LOBA 4F6VA 5IK9A 3ICMA 5HNAA 1N1BA 1WKZA 3KB9A 2RAHA 2E94A 4QPFA 1HXGA 4DWBA 2E93A 3WCFA 4OMHA 5DGNF 3M0GA 3OACA 3IBAA 3SDUA 3LEEA 3LDWA 3LGZB 4N1ZF 3EFQA 4LZ3A 2ZCSA 2ZCQA 4LA5A 2ZCOA 3MZVA 1N23A 2ZEVA 3KRFA 4JYXA 3KRPB 3KROA 4XQSF 3WJNA 3ZCDA 5ILYA 3P8LA 2AELA 3G4FA 1YHLA 1JFGA 2F94F 4P0VA 5ER8A 4RXEA 3TFPA 2Q58A 1JFAA 5C05A 2H8OA 4XQRF 3AE0A 4E1EA 1UBVA 3WEHA 1YQ7A 3ID0A 4HD1A 3N1WF 3LSNA 5I1UA 5JUZF 2DH4A 2OGDA 5EATA 4NKFA 5JA0F 5JV0F 3QQVA 3LLWA 3WCGA 5DIQF 3LG5A 5IKAA 1VG7A 3WCDA 1V4IA 3N45F 4DXJA 2J1PA 3ZOUA 4KQ5A 1UBYA 5B03A 1YYQA 3ZL6A 2Z4YA 2Z4VA 3P8RA 2AEKA 5HN8A 4JXNA 2AZLA 3WEGA 1DGPA 3M01A 2OA6A 4JZXA 4OKZA 1VG4A 3SDQA 2E92A 1WL2A 4P0WA 3VJCA 4KPJA 5ILIA 2Z4XA 4KVIA 5B02A 4LZ0A 2F92F 5ILKA 2AZJA 3ACWA 3ICZA 3CKEA 5AYPA 1ZW5A 3OYRA 3SDVA 4EA0A 1N24A 3PH7A 1YYRA 1UBXA 5AHUB 5ILHA 3LZ9A 1HXCA 5IKHA 3S9VA 5AFXA 3VJ9A 4QXSF 3M02A 4KK2A 5DJRF 1RQJA 4RYPA 3WCHA 3APZA 3Q2QA 3P5RA 1N20A 2OPNA 3WC9A 5IMIA 4MC3A 4RNQA 4RXDA 5DJVF 5IL3A 3DYFA 4LXWA 3ASXA 1HM4A 5DJPF 2P1CA 4KWDA 1WY0A 5DHKA 3ACXA 4LTVA 5KSXF 2AZKA 1V4JA 4KQUA 5ERNA 5AELA 3TFVA 2I19A 3Q2ZA 5H9DA 3VJDA 4OKMA 5IL8A 5DW7A 3VJAA 2J1OA 1YYUA 2F8CF 1HXAA 4LFVF 4KQSA 5JV2F 2AETA 4KUXA 4DWGA 3PDEA 4KVYA 4MC8A 5HN7A 2PS8A 3M9UA 5E8HA 2Z50A 1FPSA 5ERMA 3CP6A 3BNXA 4LZCA 5CG6A 1HM7A 4WK5A 3LGKA 4KFAA 2PS7A 2Q9YA 5CG5A 1YYSA 3W7FA 4RXCA 3PYBA 4JXYA 4LUUA 2Z7HA 1WL1A 4LPGF 3RYWA 3ICNA 3VJEA 3KRAB 3Q1OA 3ZMBA 2O1OA 4ZQ8A 2ZCRA 2E90A 5ILJA 3WEKA 3P41A 1WL0A 5IMPA 1N22A 1VG6A 3ACYA 1YHMA 2Z4ZA 4GP2A 5A0IA 3LJIA 3WCBA 4KPDA 1KIZA 1V4EA 4E9ZA 2F9KF 3S4JA 4DEMF 3DYHA 3ICKA 3TFNA 4F62A 5E8LA 3WJKA 3TC1A 4MC0A 3VJBA 3Q30A 5EAUA 1VG2A 2ONGA 5ILZA 4LLSA 2E8WA 4XQTF 1HX9A 3KRPA 5A0KA 4JZBA 4PVYF 3LOMA 4RXAA 3ZMCA 3WCAA 1RQIA 3N3LF 2Z78A 1V4HA 3WSBA 2VF6A 1DI1A 4Q23A 3N0FA 3M00A 3WEFA 3UCAA 4LPHF 3N49F 5B0JA 2J5CA 3AQ0A 3KRCB 4OGUA 5B01A 3N5HF 3MAVA 3WJOA 3EGTA 3VJ8A 4EA1A 3OABB 4NUAA 3V1XA 2PS5A 1KIYA 1N1ZA 2E91A 2FORA 3SDRA 2E8UA 4OMGA 4K10A 3N5JF 3DYGA 5IVGA 3WCCA 3WE9A 3B7LA 3CC9A 4LA6A 3RMGA 2Q80A 1YYTA 1YJ4A 4NG6A 4NKEA 3KBKA 3TS7A 1RTRA 4NFJF 3WEJA 3WEIA 2OPMA 2PS4A 5ILDA 3G4DA 4H5EF 2QISA 3KRAA 3RBMA 3RYEA 4LLTA 5IMNA 2EWGA 2F89F 4N9UA 5JV1F 2F7MF
chains in the Genus database with same CATH superfamily
3IPIA 3SDTA 2FTZA 1UBWA 4P0XA 5DZ2A 3NF2A 5IM1A 2Z7IA 3N46F 5HN9A 4LIXA 4F6XA 3BNYA 1WL3A 5A0JA 3OACB 1YHKA 5IK0A 2Z4WA 3LVSA 4DI5A 3WSAA 2Q9ZA 3KRFB 5B00A 2E4OA 3N1VF 3KROB 4KVDA 3P5PA 4DZWA 3V66A 2E8VA 1V4KA 4PVXF 3N3DA 2PS6A 3LMDA 3WCMA 5B0LA 4LTZA 3NPKA 3NRIA 1WMWA 4KVWA 1VG3A 4NFIF 2ONHA 3WCJA 3WCEA 4L2XF 2E8XA 3EZ3A 4LFEA 4FP4A 5IN8A 5DGMF 3QKCA 3WCIA 5B0MA 3KRCA 1PS1A 3WCLA 1EZFA 3LK5A 2F8ZF 4GP1A 3AQCB 3PKOA 4UMJA 2ZY1A 3N6KF 3SAEA 3OABA 4DHDA 3PYAA 4LFGA 2E95A 4GAXA 5DGSF 5B0IA 5DHIA 2ZEUA 4E9UA 5EROA 5EASA 4H5DF 3ADZA 3AQBB 4NFKF 5B0KA 5IK6A 2Z52A 4GA3A 3V1VA 4JVJF 3NPRA 4KKMA 2E8TA 3N0GA 5E8KA 4EA2A 4FJQA 1N21A 4H5CF 1YV5A 4LOBA 4F6VA 5IK9A 3ICMA 5HNAA 1N1BA 1WKZA 3KB9A 2RAHA 2E94A 4QPFA 1HXGA 4DWBA 2E93A 3WCFA 4OMHA 5DGNF 3M0GA 3OACA 3IBAA 3SDUA 3LEEA 3LDWA 3LGZB 4N1ZF 3EFQA 4LZ3A 2ZCSA 2ZCQA 4LA5A 2ZCOA 3MZVA 1N23A 2ZEVA 3KRFA 4JYXA 3KRPB 3KROA 4XQSF 3WJNA 3ZCDA 5ILYA 3P8LA 2AELA 3G4FA 1YHLA 1JFGA 2F94F 4P0VA 5ER8A 4RXEA 3TFPA 2Q58A 1JFAA 5C05A 2H8OA 4XQRF 3AE0A 4E1EA 1UBVA 3WEHA 1YQ7A 3ID0A 4HD1A 3N1WF 3LSNA 5I1UA 5JUZF 2DH4A 2OGDA 5EATA 4NKFA 5JA0F 5JV0F 3QQVA 3LLWA 3WCGA 5DIQF 3LG5A 5IKAA 1VG7A 3WCDA 1V4IA 3N45F 4DXJA 2J1PA 3ZOUA 4KQ5A 1UBYA 5B03A 1YYQA 3ZL6A 2Z4YA 2Z4VA 3P8RA 2AEKA 5HN8A 4JXNA 2AZLA 3WEGA 1DGPA 3M01A 2OA6A 4JZXA 4OKZA 1VG4A 3SDQA 2E92A 1WL2A 4P0WA 3VJCA 4KPJA 5ILIA 2Z4XA 4KVIA 5B02A 4LZ0A 2F92F 5ILKA 2AZJA 3ACWA 3ICZA 3CKEA 5AYPA 1ZW5A 3OYRA 3SDVA 4EA0A 1N24A 3PH7A 1YYRA 1UBXA 5AHUB 5ILHA 3LZ9A 1HXCA 5IKHA 3S9VA 5AFXA 3VJ9A 4QXSF 3M02A 4KK2A 5DJRF 1RQJA 4RYPA 3WCHA 3APZA 3Q2QA 3P5RA 1N20A 2OPNA 3WC9A 5IMIA 4MC3A 4RNQA 4RXDA 5DJVF 5IL3A 3DYFA 4LXWA 3ASXA 1HM4A 5DJPF 2P1CA 4KWDA 1WY0A 5DHKA 3ACXA 4LTVA 5KSXF 2AZKA 1V4JA 4KQUA 5ERNA 5AELA 3TFVA 2I19A 3Q2ZA 5H9DA 3VJDA 4OKMA 5IL8A 5DW7A 3VJAA 2J1OA 1YYUA 2F8CF 1HXAA 4LFVF 4KQSA 5JV2F 2AETA 4KUXA 4DWGA 3PDEA 4KVYA 4MC8A 5HN7A 2PS8A 3M9UA 5E8HA 2Z50A 1FPSA 5ERMA 3CP6A 3BNXA 4LZCA 5CG6A 1HM7A 4WK5A 3LGKA 4KFAA 2PS7A 2Q9YA 5CG5A 1YYSA 3W7FA 4RXCA 3PYBA 4JXYA 4LUUA 2Z7HA 1WL1A 4LPGF 3RYWA 3ICNA 3VJEA 3KRAB 3Q1OA 3ZMBA 2O1OA 4ZQ8A 2ZCRA 2E90A 5ILJA 3WEKA 3P41A 1WL0A 5IMPA 1N22A 1VG6A 3ACYA 1YHMA 2Z4ZA 4GP2A 5A0IA 3LJIA 3WCBA 4KPDA 1KIZA 1V4EA 4E9ZA 2F9KF 3S4JA 4DEMF 3DYHA 3ICKA 3TFNA 4F62A 5E8LA 3WJKA 3TC1A 4MC0A 3VJBA 3Q30A 5EAUA 1VG2A 2ONGA 5ILZA 4LLSA 2E8WA 4XQTF 1HX9A 3KRPA 5A0KA 4JZBA 4PVYF 3LOMA 4RXAA 3ZMCA 3WCAA 1RQIA 3N3LF 2Z78A 1V4HA 3WSBA 2VF6A 1DI1A 4Q23A 3N0FA 3M00A 3WEFA 3UCAA 4LPHF 3N49F 5B0JA 2J5CA 3AQ0A 3KRCB 4OGUA 5B01A 3N5HF 3MAVA 3WJOA 3EGTA 3VJ8A 4EA1A 3OABB 4NUAA 3V1XA 2PS5A 1KIYA 1N1ZA 2E91A 2FORA 3SDRA 2E8UA 4OMGA 4K10A 3N5JF 3DYGA 5IVGA 3WCCA 3WE9A 3B7LA 3CC9A 4LA6A 3RMGA 2Q80A 1YYTA 1YJ4A 4NG6A 4NKEA 3KBKA 3TS7A 1RTRA 4NFJF 3WEJA 3WEIA 2OPMA 2PS4A 5ILDA 3G4DA 4H5EF 2QISA 3KRAA 3RBMA 3RYEA 4LLTA 5IMNA 2EWGA 2F89F 4N9UA 5JV1F 2F7MF
chains in the Genus database with same CATH topology
3IPIA 3SDTA 2FTZA 1UBWA 4P0XA 5DZ2A 3NF2A 5IM1A 2Z7IA 3N46F 5HN9A 4LIXA 4F6XA 3BNYA 1WL3A 5A0JA 3OACB 1YHKA 5IK0A 2Z4WA 3LVSA 4DI5A 3WSAA 2Q9ZA 3KRFB 5B00A 2E4OA 3N1VF 3KROB 4KVDA 3P5PA 4DZWA 3V66A 2E8VA 1V4KA 4PVXF 3N3DA 2PS6A 3LMDA 3WCMA 5B0LA 4LTZA 3NPKA 3NRIA 1WMWA 4KVWA 1VG3A 4NFIF 2ONHA 3WCJA 3WCEA 4L2XF 2E8XA 3EZ3A 4LFEA 4FP4A 5IN8A 5DGMF 3QKCA 3WCIA 5B0MA 3KRCA 1PS1A 3WCLA 1EZFA 3LK5A 2F8ZF 4GP1A 3AQCB 3PKOA 4UMJA 2ZY1A 3N6KF 3SAEA 3OABA 4DHDA 3PYAA 4LFGA 2E95A 4GAXA 5DGSF 5B0IA 5DHIA 2ZEUA 4E9UA 5EROA 5EASA 4H5DF 3ADZA 3AQBB 4NFKF 5B0KA 5IK6A 2Z52A 4GA3A 3V1VA 4JVJF 3NPRA 4KKMA 2E8TA 3N0GA 5E8KA 4EA2A 4FJQA 1N21A 4H5CF 1YV5A 4LOBA 4F6VA 5IK9A 3ICMA 5HNAA 1N1BA 1WKZA 3KB9A 2RAHA 2E94A 4QPFA 1HXGA 4DWBA 2E93A 3WCFA 4OMHA 5DGNF 3M0GA 3OACA 3IBAA 3SDUA 3LEEA 3LDWA 3LGZB 4N1ZF 3EFQA 4LZ3A 2ZCSA 2ZCQA 4LA5A 2ZCOA 3MZVA 1N23A 2ZEVA 3KRFA 4JYXA 3KRPB 3KROA 4XQSF 3WJNA 3ZCDA 5ILYA 3P8LA 2AELA 3G4FA 1YHLA 1JFGA 2F94F 4P0VA 5ER8A 4RXEA 3TFPA 2Q58A 1JFAA 5C05A 2H8OA 4XQRF 3AE0A 4E1EA 1UBVA 3WEHA 1YQ7A 3ID0A 4HD1A 3N1WF 3LSNA 5I1UA 5JUZF 2DH4A 2OGDA 5EATA 4NKFA 5JA0F 5JV0F 3QQVA 3LLWA 3WCGA 5DIQF 3LG5A 5IKAA 1VG7A 3WCDA 1V4IA 3N45F 4DXJA 2J1PA 3ZOUA 4KQ5A 1UBYA 5B03A 1YYQA 3ZL6A 2Z4YA 2Z4VA 3P8RA 2AEKA 5HN8A 4JXNA 2AZLA 3WEGA 1DGPA 3M01A 2OA6A 4JZXA 4OKZA 1VG4A 3SDQA 2E92A 1WL2A 4P0WA 3VJCA 4KPJA 5ILIA 2Z4XA 4KVIA 5B02A 4LZ0A 2F92F 5ILKA 2AZJA 3ACWA 3ICZA 3CKEA 5AYPA 1ZW5A 3OYRA 3SDVA 4EA0A 1N24A 3PH7A 1YYRA 1UBXA 5AHUB 5ILHA 3LZ9A 1HXCA 5IKHA 3S9VA 5AFXA 3VJ9A 4QXSF 3M02A 4KK2A 5DJRF 1RQJA 4RYPA 3WCHA 3APZA 3Q2QA 3P5RA 1N20A 2OPNA 3WC9A 5IMIA 4MC3A 4RNQA 4RXDA 5DJVF 5IL3A 3DYFA 4LXWA 3ASXA 1HM4A 5DJPF 2P1CA 4KWDA 1WY0A 5DHKA 3ACXA 4LTVA 5KSXF 2AZKA 1V4JA 4KQUA 5ERNA 5AELA 3TFVA 2I19A 3Q2ZA 5H9DA 3VJDA 4OKMA 5IL8A 5DW7A 3VJAA 2J1OA 1YYUA 2F8CF 1HXAA 4LFVF 4KQSA 5JV2F 2AETA 4KUXA 4DWGA 3PDEA 4KVYA 4MC8A 5HN7A 2PS8A 3M9UA 5E8HA 2Z50A 1FPSA 5ERMA 3CP6A 3BNXA 4LZCA 5CG6A 1HM7A 4WK5A 3LGKA 4KFAA 2PS7A 2Q9YA 5CG5A 1YYSA 3W7FA 4RXCA 3PYBA 4JXYA 4LUUA 2Z7HA 1WL1A 4LPGF 3RYWA 3ICNA 3VJEA 3KRAB 3Q1OA 3ZMBA 2O1OA 4ZQ8A 2ZCRA 2E90A 5ILJA 3WEKA 3P41A 1WL0A 5IMPA 1N22A 1VG6A 3ACYA 1YHMA 2Z4ZA 4GP2A 5A0IA 3LJIA 3WCBA 4KPDA 1KIZA 1V4EA 4E9ZA 2F9KF 3S4JA 4DEMF 3DYHA 3ICKA 3TFNA 4F62A 5E8LA 3WJKA 3TC1A 4MC0A 3VJBA 3Q30A 5EAUA 1VG2A 2ONGA 5ILZA 4LLSA 2E8WA 4XQTF 1HX9A 3KRPA 5A0KA 4JZBA 4PVYF 3LOMA 4RXAA 3ZMCA 3WCAA 1RQIA 3N3LF 2Z78A 1V4HA 3WSBA 2VF6A 1DI1A 4Q23A 3N0FA 3M00A 3WEFA 3UCAA 4LPHF 3N49F 5B0JA 2J5CA 3AQ0A 3KRCB 4OGUA 5B01A 3N5HF 3MAVA 3WJOA 3EGTA 3VJ8A 4EA1A 3OABB 4NUAA 3V1XA 2PS5A 1KIYA 1N1ZA 2E91A 2FORA 3SDRA 2E8UA 4OMGA 4K10A 3N5JF 3DYGA 5IVGA 3WCCA 3WE9A 3B7LA 3CC9A 4LA6A 3RMGA 2Q80A 1YYTA 1YJ4A 4NG6A 4NKEA 3KBKA 3TS7A 1RTRA 4NFJF 3WEJA 3WEIA 2OPMA 2PS4A 5ILDA 3G4DA 4H5EF 2QISA 3KRAA 3RBMA 3RYEA 4LLTA 5IMNA 2EWGA 2F89F 4N9UA 5JV1F 2F7MF
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3IPI A;  3SDT A;  2FTZ A;  1UBW A;  4P0X A;  5DZ2 A;  3NF2 A;  5IM1 A;  2Z7I A;  3N46 F;  5HN9 A;  4LIX A;  4F6X A;  3BNY A;  1WL3 A;  5A0J A;  3OAC B;  1YHK A;  5IK0 A;  2Z4W A;  3LVS A;  4DI5 A;  3WSA A;  2Q9Z A;  3KRF B;  5B00 A;  2E4O A;  3N1V F;  3KRO B;  4KVD A;  3P5P A;  4DZW A;  3V66 A;  2E8V A;  1V4K A;  4PVX F;  3N3D A;  2PS6 A;  3LMD A;  3WCM A;  5B0L A;  4LTZ A;  3NPK A;  3NRI A;  1WMW A;  4KVW A;  1VG3 A;  4NFI F;  2ONH A;  3WCJ A;  3WCE A;  4L2X F;  2E8X A;  3EZ3 A;  4LFE A;  4FP4 A;  5IN8 A;  5DGM F;  3QKC A;  3WCI A;  5B0M A;  3KRC A;  1PS1 A;  3WCL A;  1EZF A;  3LK5 A;  2F8Z F;  4GP1 A;  3AQC B;  3PKO A;  4UMJ A;  2ZY1 A;  3N6K F;  3SAE A;  3OAB A;  4DHD A;  3PYA A;  4LFG A;  2E95 A;  4GAX A;  5DGS F;  5B0I A;  5DHI A;  2ZEU A;  4E9U A;  5ERO A;  5EAS A;  4H5D F;  3ADZ A;  3AQB B;  4NFK F;  5B0K A;  5IK6 A;  2Z52 A;  4GA3 A;  3V1V A;  4JVJ F;  3NPR A;  4KKM A;  2E8T A;  3N0G A;  5E8K A;  4EA2 A;  4FJQ A;  1N21 A;  4H5C F;  1YV5 A;  4LOB A;  4F6V A;  5IK9 A;  3ICM A;  5HNA A;  1N1B A;  1WKZ A;  3KB9 A;  2RAH A;  2E94 A;  4QPF A;  1HXG A;  4DWB A;  2E93 A;  3WCF A;  4OMH A;  5DGN F;  3M0G A;  3OAC A;  3IBA A;  3SDU A;  3LEE A;  3LDW A;  3LGZ B;  4N1Z F;  3EFQ A;  4LZ3 A;  2ZCS A;  2ZCQ A;  4LA5 A;  2ZCO A;  3MZV A;  1N23 A;  2ZEV A;  3KRF A;  4JYX A;  3KRP B;  3KRO A;  4XQS F;  3WJN A;  3ZCD A;  5ILY A;  3P8L A;  2AEL A;  3G4F A;  1YHL A;  1JFG A;  2F94 F;  4P0V A;  5ER8 A;  4RXE A;  3TFP A;  2Q58 A;  1JFA A;  5C05 A;  2H8O A;  4XQR F;  3AE0 A;  4E1E A;  1UBV A;  3WEH A;  1YQ7 A;  3ID0 A;  4HD1 A;  3N1W F;  3LSN A;  5I1U A;  5JUZ F;  2DH4 A;  2OGD A;  5EAT A;  4NKF A;  5JA0 F;  5JV0 F;  3QQV A;  3LLW A;  3WCG A;  5DIQ F;  3LG5 A;  5IKA A;  1VG7 A;  3WCD A;  1V4I A;  3N45 F;  4DXJ A;  2J1P A;  3ZOU A;  4KQ5 A;  1UBY A;  5B03 A;  1YYQ A;  3ZL6 A;  2Z4Y A;  2Z4V A;  3P8R A;  2AEK A;  5HN8 A;  4JXN A;  2AZL A;  3WEG A;  1DGP A;  3M01 A;  2OA6 A;  4JZX A;  4OKZ A;  1VG4 A;  3SDQ A;  2E92 A;  1WL2 A;  4P0W A;  3VJC A;  4KPJ A;  5ILI A;  2Z4X A;  4KVI A;  5B02 A;  4LZ0 A;  2F92 F;  5ILK A;  2AZJ A;  3ACW A;  3ICZ A;  3CKE A;  5AYP A;  1ZW5 A;  3OYR A;  3SDV A;  4EA0 A;  1N24 A;  3PH7 A;  1YYR A;  1UBX A;  5AHU B;  5ILH A;  3LZ9 A;  1HXC A;  5IKH A;  3S9V A;  5AFX A;  3VJ9 A;  4QXS F;  3M02 A;  4KK2 A;  5DJR F;  1RQJ A;  4RYP A;  3WCH A;  3APZ A;  3Q2Q A;  3P5R A;  1N20 A;  2OPN A;  3WC9 A;  5IMI A;  4MC3 A;  4RNQ A;  4RXD A;  5DJV F;  5IL3 A;  3DYF A;  4LXW A;  3ASX A;  1HM4 A;  5DJP F;  2P1C A;  4KWD A;  1WY0 A;  5DHK A;  3ACX A;  4LTV A;  5KSX F;  2AZK A;  1V4J A;  4KQU A;  5ERN A;  5AEL A;  3TFV A;  2I19 A;  3Q2Z A;  5H9D A;  3VJD A;  4OKM A;  5IL8 A;  5DW7 A;  3VJA A;  2J1O A;  1YYU A;  2F8C F;  1HXA A;  4LFV F;  4KQS A;  5JV2 F;  2AET A;  4KUX A;  4DWG A;  3PDE A;  4KVY A;  4MC8 A;  5HN7 A;  2PS8 A;  3M9U A;  5E8H A;  2Z50 A;  1FPS A;  5ERM A;  3CP6 A;  3BNX A;  4LZC A;  5CG6 A;  1HM7 A;  4WK5 A;  3LGK A;  4KFA A;  2PS7 A;  2Q9Y A;  5CG5 A;  1YYS A;  3W7F A;  4RXC A;  3PYB A;  4JXY A;  4LUU A;  2Z7H A;  1WL1 A;  4LPG F;  3RYW A;  3ICN A;  3VJE A;  3KRA B;  3Q1O A;  3ZMB A;  2O1O A;  4ZQ8 A;  2ZCR A;  2E90 A;  5ILJ A;  3WEK A;  3P41 A;  1WL0 A;  5IMP A;  1N22 A;  1VG6 A;  3ACY A;  1YHM A;  2Z4Z A;  4GP2 A;  5A0I A;  3LJI A;  3WCB A;  4KPD A;  1KIZ A;  1V4E A;  4E9Z A;  2F9K F;  3S4J A;  4DEM F;  3DYH A;  3ICK A;  3TFN A;  4F62 A;  5E8L A;  3WJK A;  3TC1 A;  4MC0 A;  3VJB A;  3Q30 A;  5EAU A;  1VG2 A;  2ONG A;  5ILZ A;  4LLS A;  2E8W A;  4XQT F;  1HX9 A;  3KRP A;  5A0K A;  4JZB A;  4PVY F;  3LOM A;  4RXA A;  3ZMC A;  3WCA A;  1RQI A;  3N3L F;  2Z78 A;  1V4H A;  3WSB A;  2VF6 A;  1DI1 A;  4Q23 A;  3N0F A;  3M00 A;  3WEF A;  3UCA A;  4LPH F;  3N49 F;  5B0J A;  2J5C A;  3AQ0 A;  3KRC B;  4OGU A;  5B01 A;  3N5H F;  3MAV A;  3WJO A;  3EGT A;  3VJ8 A;  4EA1 A;  3OAB B;  4NUA A;  3V1X A;  2PS5 A;  1KIY A;  1N1Z A;  2E91 A;  2FOR A;  3SDR A;  2E8U A;  4OMG A;  4K10 A;  3N5J F;  3DYG A;  5IVG A;  3WCC A;  3WE9 A;  3B7L A;  3CC9 A;  4LA6 A;  3RMG A;  2Q80 A;  1YYT A;  1YJ4 A;  4NG6 A;  4NKE A;  3KBK A;  3TS7 A;  1RTR A;  4NFJ F;  3WEJ A;  3WEI A;  2OPM A;  2PS4 A;  5ILD A;  3G4D A;  4H5E F;  2QIS A;  3KRA A;  3RBM A;  3RYE A;  4LLT A;  5IMN A;  2EWG A;  2F89 F;  4N9U A;  5JV1 F;  2F7M F; 
#chains in the Genus database with same CATH topology
 3IPI A;  3SDT A;  2FTZ A;  1UBW A;  4P0X A;  5DZ2 A;  3NF2 A;  5IM1 A;  2Z7I A;  3N46 F;  5HN9 A;  4LIX A;  4F6X A;  3BNY A;  1WL3 A;  5A0J A;  3OAC B;  1YHK A;  5IK0 A;  2Z4W A;  3LVS A;  4DI5 A;  3WSA A;  2Q9Z A;  3KRF B;  5B00 A;  2E4O A;  3N1V F;  3KRO B;  4KVD A;  3P5P A;  4DZW A;  3V66 A;  2E8V A;  1V4K A;  4PVX F;  3N3D A;  2PS6 A;  3LMD A;  3WCM A;  5B0L A;  4LTZ A;  3NPK A;  3NRI A;  1WMW A;  4KVW A;  1VG3 A;  4NFI F;  2ONH A;  3WCJ A;  3WCE A;  4L2X F;  2E8X A;  3EZ3 A;  4LFE A;  4FP4 A;  5IN8 A;  5DGM F;  3QKC A;  3WCI A;  5B0M A;  3KRC A;  1PS1 A;  3WCL A;  1EZF A;  3LK5 A;  2F8Z F;  4GP1 A;  3AQC B;  3PKO A;  4UMJ A;  2ZY1 A;  3N6K F;  3SAE A;  3OAB A;  4DHD A;  3PYA A;  4LFG A;  2E95 A;  4GAX A;  5DGS F;  5B0I A;  5DHI A;  2ZEU A;  4E9U A;  5ERO A;  5EAS A;  4H5D F;  3ADZ A;  3AQB B;  4NFK F;  5B0K A;  5IK6 A;  2Z52 A;  4GA3 A;  3V1V A;  4JVJ F;  3NPR A;  4KKM A;  2E8T A;  3N0G A;  5E8K A;  4EA2 A;  4FJQ A;  1N21 A;  4H5C F;  1YV5 A;  4LOB A;  4F6V A;  5IK9 A;  3ICM A;  5HNA A;  1N1B A;  1WKZ A;  3KB9 A;  2RAH A;  2E94 A;  4QPF A;  1HXG A;  4DWB A;  2E93 A;  3WCF A;  4OMH A;  5DGN F;  3M0G A;  3OAC A;  3IBA A;  3SDU A;  3LEE A;  3LDW A;  3LGZ B;  4N1Z F;  3EFQ A;  4LZ3 A;  2ZCS A;  2ZCQ A;  4LA5 A;  2ZCO A;  3MZV A;  1N23 A;  2ZEV A;  3KRF A;  4JYX A;  3KRP B;  3KRO A;  4XQS F;  3WJN A;  3ZCD A;  5ILY A;  3P8L A;  2AEL A;  3G4F A;  1YHL A;  1JFG A;  2F94 F;  4P0V A;  5ER8 A;  4RXE A;  3TFP A;  2Q58 A;  1JFA A;  5C05 A;  2H8O A;  4XQR F;  3AE0 A;  4E1E A;  1UBV A;  3WEH A;  1YQ7 A;  3ID0 A;  4HD1 A;  3N1W F;  3LSN A;  5I1U A;  5JUZ F;  2DH4 A;  2OGD A;  5EAT A;  4NKF A;  5JA0 F;  5JV0 F;  3QQV A;  3LLW A;  3WCG A;  5DIQ F;  3LG5 A;  5IKA A;  1VG7 A;  3WCD A;  1V4I A;  3N45 F;  4DXJ A;  2J1P A;  3ZOU A;  4KQ5 A;  1UBY A;  5B03 A;  1YYQ A;  3ZL6 A;  2Z4Y A;  2Z4V A;  3P8R A;  2AEK A;  5HN8 A;  4JXN A;  2AZL A;  3WEG A;  1DGP A;  3M01 A;  2OA6 A;  4JZX A;  4OKZ A;  1VG4 A;  3SDQ A;  2E92 A;  1WL2 A;  4P0W A;  3VJC A;  4KPJ A;  5ILI A;  2Z4X A;  4KVI A;  5B02 A;  4LZ0 A;  2F92 F;  5ILK A;  2AZJ A;  3ACW A;  3ICZ A;  3CKE A;  5AYP A;  1ZW5 A;  3OYR A;  3SDV A;  4EA0 A;  1N24 A;  3PH7 A;  1YYR A;  1UBX A;  5AHU B;  5ILH A;  3LZ9 A;  1HXC A;  5IKH A;  3S9V A;  5AFX A;  3VJ9 A;  4QXS F;  3M02 A;  4KK2 A;  5DJR F;  1RQJ A;  4RYP A;  3WCH A;  3APZ A;  3Q2Q A;  3P5R A;  1N20 A;  2OPN A;  3WC9 A;  5IMI A;  4MC3 A;  4RNQ A;  4RXD A;  5DJV F;  5IL3 A;  3DYF A;  4LXW A;  3ASX A;  1HM4 A;  5DJP F;  2P1C A;  4KWD A;  1WY0 A;  5DHK A;  3ACX A;  4LTV A;  5KSX F;  2AZK A;  1V4J A;  4KQU A;  5ERN A;  5AEL A;  3TFV A;  2I19 A;  3Q2Z A;  5H9D A;  3VJD A;  4OKM A;  5IL8 A;  5DW7 A;  3VJA A;  2J1O A;  1YYU A;  2F8C F;  1HXA A;  4LFV F;  4KQS A;  5JV2 F;  2AET A;  4KUX A;  4DWG A;  3PDE A;  4KVY A;  4MC8 A;  5HN7 A;  2PS8 A;  3M9U A;  5E8H A;  2Z50 A;  1FPS A;  5ERM A;  3CP6 A;  3BNX A;  4LZC A;  5CG6 A;  1HM7 A;  4WK5 A;  3LGK A;  4KFA A;  2PS7 A;  2Q9Y A;  5CG5 A;  1YYS A;  3W7F A;  4RXC A;  3PYB A;  4JXY A;  4LUU A;  2Z7H A;  1WL1 A;  4LPG F;  3RYW A;  3ICN A;  3VJE A;  3KRA B;  3Q1O A;  3ZMB A;  2O1O A;  4ZQ8 A;  2ZCR A;  2E90 A;  5ILJ A;  3WEK A;  3P41 A;  1WL0 A;  5IMP A;  1N22 A;  1VG6 A;  3ACY A;  1YHM A;  2Z4Z A;  4GP2 A;  5A0I A;  3LJI A;  3WCB A;  4KPD A;  1KIZ A;  1V4E A;  4E9Z A;  2F9K F;  3S4J A;  4DEM F;  3DYH A;  3ICK A;  3TFN A;  4F62 A;  5E8L A;  3WJK A;  3TC1 A;  4MC0 A;  3VJB A;  3Q30 A;  5EAU A;  1VG2 A;  2ONG A;  5ILZ A;  4LLS A;  2E8W A;  4XQT F;  1HX9 A;  3KRP A;  5A0K A;  4JZB A;  4PVY F;  3LOM A;  4RXA A;  3ZMC A;  3WCA A;  1RQI A;  3N3L F;  2Z78 A;  1V4H A;  3WSB A;  2VF6 A;  1DI1 A;  4Q23 A;  3N0F A;  3M00 A;  3WEF A;  3UCA A;  4LPH F;  3N49 F;  5B0J A;  2J5C A;  3AQ0 A;  3KRC B;  4OGU A;  5B01 A;  3N5H F;  3MAV A;  3WJO A;  3EGT A;  3VJ8 A;  4EA1 A;  3OAB B;  4NUA A;  3V1X A;  2PS5 A;  1KIY A;  1N1Z A;  2E91 A;  2FOR A;  3SDR A;  2E8U A;  4OMG A;  4K10 A;  3N5J F;  3DYG A;  5IVG A;  3WCC A;  3WE9 A;  3B7L A;  3CC9 A;  4LA6 A;  3RMG A;  2Q80 A;  1YYT A;  1YJ4 A;  4NG6 A;  4NKE A;  3KBK A;  3TS7 A;  1RTR A;  4NFJ F;  3WEJ A;  3WEI A;  2OPM A;  2PS4 A;  5ILD A;  3G4D A;  4H5E F;  2QIS A;  3KRA A;  3RBM A;  3RYE A;  4LLT A;  5IMN A;  2EWG A;  2F89 F;  4N9U A;  5JV1 F;  2F7M F; 
#chains in the Genus database with same CATH homology
 3IPI A;  3SDT A;  2FTZ A;  1UBW A;  4P0X A;  5DZ2 A;  3NF2 A;  5IM1 A;  2Z7I A;  3N46 F;  5HN9 A;  4LIX A;  4F6X A;  3BNY A;  1WL3 A;  5A0J A;  3OAC B;  1YHK A;  5IK0 A;  2Z4W A;  3LVS A;  4DI5 A;  3WSA A;  2Q9Z A;  3KRF B;  5B00 A;  2E4O A;  3N1V F;  3KRO B;  4KVD A;  3P5P A;  4DZW A;  3V66 A;  2E8V A;  1V4K A;  4PVX F;  3N3D A;  2PS6 A;  3LMD A;  3WCM A;  5B0L A;  4LTZ A;  3NPK A;  3NRI A;  1WMW A;  4KVW A;  1VG3 A;  4NFI F;  2ONH A;  3WCJ A;  3WCE A;  4L2X F;  2E8X A;  3EZ3 A;  4LFE A;  4FP4 A;  5IN8 A;  5DGM F;  3QKC A;  3WCI A;  5B0M A;  3KRC A;  1PS1 A;  3WCL A;  1EZF A;  3LK5 A;  2F8Z F;  4GP1 A;  3AQC B;  3PKO A;  4UMJ A;  2ZY1 A;  3N6K F;  3SAE A;  3OAB A;  4DHD A;  3PYA A;  4LFG A;  2E95 A;  4GAX A;  5DGS F;  5B0I A;  5DHI A;  2ZEU A;  4E9U A;  5ERO A;  5EAS A;  4H5D F;  3ADZ A;  3AQB B;  4NFK F;  5B0K A;  5IK6 A;  2Z52 A;  4GA3 A;  3V1V A;  4JVJ F;  3NPR A;  4KKM A;  2E8T A;  3N0G A;  5E8K A;  4EA2 A;  4FJQ A;  1N21 A;  4H5C F;  1YV5 A;  4LOB A;  4F6V A;  5IK9 A;  3ICM A;  5HNA A;  1N1B A;  1WKZ A;  3KB9 A;  2RAH A;  2E94 A;  4QPF A;  1HXG A;  4DWB A;  2E93 A;  3WCF A;  4OMH A;  5DGN F;  3M0G A;  3OAC A;  3IBA A;  3SDU A;  3LEE A;  3LDW A;  3LGZ B;  4N1Z F;  3EFQ A;  4LZ3 A;  2ZCS A;  2ZCQ A;  4LA5 A;  2ZCO A;  3MZV A;  1N23 A;  2ZEV A;  3KRF A;  4JYX A;  3KRP B;  3KRO A;  4XQS F;  3WJN A;  3ZCD A;  5ILY A;  3P8L A;  2AEL A;  3G4F A;  1YHL A;  1JFG A;  2F94 F;  4P0V A;  5ER8 A;  4RXE A;  3TFP A;  2Q58 A;  1JFA A;  5C05 A;  2H8O A;  4XQR F;  3AE0 A;  4E1E A;  1UBV A;  3WEH A;  1YQ7 A;  3ID0 A;  4HD1 A;  3N1W F;  3LSN A;  5I1U A;  5JUZ F;  2DH4 A;  2OGD A;  5EAT A;  4NKF A;  5JA0 F;  5JV0 F;  3QQV A;  3LLW A;  3WCG A;  5DIQ F;  3LG5 A;  5IKA A;  1VG7 A;  3WCD A;  1V4I A;  3N45 F;  4DXJ A;  2J1P A;  3ZOU A;  4KQ5 A;  1UBY A;  5B03 A;  1YYQ A;  3ZL6 A;  2Z4Y A;  2Z4V A;  3P8R A;  2AEK A;  5HN8 A;  4JXN A;  2AZL A;  3WEG A;  1DGP A;  3M01 A;  2OA6 A;  4JZX A;  4OKZ A;  1VG4 A;  3SDQ A;  2E92 A;  1WL2 A;  4P0W A;  3VJC A;  4KPJ A;  5ILI A;  2Z4X A;  4KVI A;  5B02 A;  4LZ0 A;  2F92 F;  5ILK A;  2AZJ A;  3ACW A;  3ICZ A;  3CKE A;  5AYP A;  1ZW5 A;  3OYR A;  3SDV A;  4EA0 A;  1N24 A;  3PH7 A;  1YYR A;  1UBX A;  5AHU B;  5ILH A;  3LZ9 A;  1HXC A;  5IKH A;  3S9V A;  5AFX A;  3VJ9 A;  4QXS F;  3M02 A;  4KK2 A;  5DJR F;  1RQJ A;  4RYP A;  3WCH A;  3APZ A;  3Q2Q A;  3P5R A;  1N20 A;  2OPN A;  3WC9 A;  5IMI A;  4MC3 A;  4RNQ A;  4RXD A;  5DJV F;  5IL3 A;  3DYF A;  4LXW A;  3ASX A;  1HM4 A;  5DJP F;  2P1C A;  4KWD A;  1WY0 A;  5DHK A;  3ACX A;  4LTV A;  5KSX F;  2AZK A;  1V4J A;  4KQU A;  5ERN A;  5AEL A;  3TFV A;  2I19 A;  3Q2Z A;  5H9D A;  3VJD A;  4OKM A;  5IL8 A;  5DW7 A;  3VJA A;  2J1O A;  1YYU A;  2F8C F;  1HXA A;  4LFV F;  4KQS A;  5JV2 F;  2AET A;  4KUX A;  4DWG A;  3PDE A;  4KVY A;  4MC8 A;  5HN7 A;  2PS8 A;  3M9U A;  5E8H A;  2Z50 A;  1FPS A;  5ERM A;  3CP6 A;  3BNX A;  4LZC A;  5CG6 A;  1HM7 A;  4WK5 A;  3LGK A;  4KFA A;  2PS7 A;  2Q9Y A;  5CG5 A;  1YYS A;  3W7F A;  4RXC A;  3PYB A;  4JXY A;  4LUU A;  2Z7H A;  1WL1 A;  4LPG F;  3RYW A;  3ICN A;  3VJE A;  3KRA B;  3Q1O A;  3ZMB A;  2O1O A;  4ZQ8 A;  2ZCR A;  2E90 A;  5ILJ A;  3WEK A;  3P41 A;  1WL0 A;  5IMP A;  1N22 A;  1VG6 A;  3ACY A;  1YHM A;  2Z4Z A;  4GP2 A;  5A0I A;  3LJI A;  3WCB A;  4KPD A;  1KIZ A;  1V4E A;  4E9Z A;  2F9K F;  3S4J A;  4DEM F;  3DYH A;  3ICK A;  3TFN A;  4F62 A;  5E8L A;  3WJK A;  3TC1 A;  4MC0 A;  3VJB A;  3Q30 A;  5EAU A;  1VG2 A;  2ONG A;  5ILZ A;  4LLS A;  2E8W A;  4XQT F;  1HX9 A;  3KRP A;  5A0K A;  4JZB A;  4PVY F;  3LOM A;  4RXA A;  3ZMC A;  3WCA A;  1RQI A;  3N3L F;  2Z78 A;  1V4H A;  3WSB A;  2VF6 A;  1DI1 A;  4Q23 A;  3N0F A;  3M00 A;  3WEF A;  3UCA A;  4LPH F;  3N49 F;  5B0J A;  2J5C A;  3AQ0 A;  3KRC B;  4OGU A;  5B01 A;  3N5H F;  3MAV A;  3WJO A;  3EGT A;  3VJ8 A;  4EA1 A;  3OAB B;  4NUA A;  3V1X A;  2PS5 A;  1KIY A;  1N1Z A;  2E91 A;  2FOR A;  3SDR A;  2E8U A;  4OMG A;  4K10 A;  3N5J F;  3DYG A;  5IVG A;  3WCC A;  3WE9 A;  3B7L A;  3CC9 A;  4LA6 A;  3RMG A;  2Q80 A;  1YYT A;  1YJ4 A;  4NG6 A;  4NKE A;  3KBK A;  3TS7 A;  1RTR A;  4NFJ F;  3WEJ A;  3WEI A;  2OPM A;  2PS4 A;  5ILD A;  3G4D A;  4H5E F;  2QIS A;  3KRA A;  3RBM A;  3RYE A;  4LLT A;  5IMN A;  2EWG A;  2F89 F;  4N9U A;  5JV1 F;  2F7M F; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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