3VJCA

Crystal structure of the human squalene synthase in complex with zaragozic acid a
Total Genus 133
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
133
sequence length
334
structure length
334
Chain Sequence
LSSSLKTCYKYLNQTSRSFAAVIQALDGEMRNAVCIFYLVLRALDTLEDDMTISVEKKVPLLHNFHSFLYQPDWRFMESKEKDRQVLEDFPTISLEFRNLAEKYQTVIADICRRMGIGMAEFLDKHVTSEQEWDKYCHYVAGLVGIGLSRLFSASEFEDPLVGEDTERANSMGLFLQKTNIIRDYLEDQQGGREFWPQEVWSRYVKKLGDFAKPENIDLAVQCLNELITNALHHIPDVITYLSRLRNQSVFNFCAIPQVMAIATLAACYNNQQVFKGAVKIRKGQAVTLMMDATNMPAVKAIIYQYMEEIYHRIPDSDPSSSKTRQIISTIRTQ
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Binding modes of zaragozic acid A to human squalene synthase and staphylococcal dehydrosqualene synthase
pubmed doi rcsb
molecule tags Transferase/transferase inhibitor
source organism Homo sapiens
molecule keywords Squalene synthase
total genus 133
structure length 334
sequence length 334
chains with identical sequence B, C, D, E, F
ec nomenclature ec 2.5.1.21: Squalene synthase.
pdb deposition date 2011-10-14

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00494 SQS_PSY Squalene/phytoene synthase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.600.10 Mainly Alpha Orthogonal Bundle Farnesyl Diphosphate Synthase Farnesyl Diphosphate Synthase 3vjcA00
3ICMA 3NPRA 5CG5A 4RXEA 3G4DA 3WEGA 3VJBA 1UBXA 2AEKA 2Z78A 1N22A 2E4OA 4KQSA 5JV1F 3M02A 4E9UA 1YV5A 4KQ5A 3ICZA 3KRCB 3WCHA 3ADZA 5I1UA 5HNAA 1DGPA 3WCCA 3DYGA 2PS7A 4N9UA 3AE0A 1YYQA 3OABA 3P8RA 3VJ8A 5HN8A 4GP1A 4H5DF 4LLSA 5EASA 1WL3A 3QKCA 2OPNA 3KRAA 4JYXA 2E95A 5B01A 4KUXA 4OKZA 5IL3A 4KK2A 3WEKA 4OKMA 5ER8A 1UBWA 2FORA 3VJEA 3ID0A 3Q30A 3EGTA 3N6KF 5A0JA 2RAHA 3EFQA 4DI5A 2ZCOA 3ICNA 4ZQ8A 5C05A 5JV0F 3S9VA 4NFIF 4P0WA 3WCBA 1HXGA 4KVDA 3N0GA 2E8VA 5H9DA 1YYTA 3LGKA 2O1OA 4RNQA 5B0JA 4LTZA 5B00A 4PVYF 3RBMA 3M01A 5IK0A 4LLTA 3ZOUA 2Q9ZA 3OABB 5JA0F 2E8TA 3N3DA 3WCFA 4QPFA 2Q80A 3KRAB 1RTRA 3LJIA 3NPKA 1HXCA 3N45F 4KPDA 4XQSF 3N3LF 5IK6A 3ASXA 1WKZA 4E1EA 4NG6A 3N0FA 2ZEVA 3WEJA 3AQ0A 4NFKF 2E8WA 1KIZA 3RYWA 5ERNA 2Q9YA 5B0KA 4F6XA 5B03A 3LVSA 2ONHA 3SAEA 2ZCRA 5DJPF 4RXDA 1HX9A 3AQCB 3KRFA 3WCJA 5IMIA 4PVXF 1N1BA 1DI1A 4KVWA 4RXCA 5DHKA 1VG3A 4LOBA 1N24A 2PS6A 3WSAA 4GA3A 2Z4XA 2Z4WA 4K10A 2I19A 3KRPA 5DW7A 1WY0A 3WCEA 2OA6A 2ZCSA 3VJCA 3LMDA 5DJRF 3ACXA 3ACWA 4FP4A 3SDUA 1PS1A 4F6VA 2OPMA 2E92A 3B7LA 2Z4VA 3DYHA 2VF6A 4NFJF 4NKEA 5IL8A 3VJ9A 3PDEA 2OGDA 5IM1A 5DGNF 5E8KA 5DIQF 4OMHA 3RYEA 2E94A 4MC8A 3V66A 3VJAA 5IKAA 3TS7A 1YHMA 3KRFB 4LXWA 4P0XA 3G4FA 4JZXA 2E93A 5ERMA 2E8UA 2AETA 2PS8A 3KBKA 1YHLA 5IMNA 3VJDA 3N5JF 4KQUA 2FTZA 5HN7A 4LFVF 1YJ4A 1WMWA 2PS5A 3KRPB 2ZEUA 3BNYA 3PKOA 4JVJF 1VG7A 4OMGA 5DGSF 5DGMF 1V4HA 4LZCA 1V4EA 2F92F 4JXYA 2EWGA 3OYRA 1JFAA 4DZWA 3V1VA 1HM4A 5ILIA 3KB9A 1N20A 3MAVA 4H5EF 3LGZB 5HN9A 3V1XA 4FJQA 3CC9A 4WK5A 3MZVA 3S4JA 4EA1A 1HM7A 1WL0A 5IVGA 5IMPA 3PYBA 3WEHA 4JZBA 2ZY1A 2Z52A 3WCMA 1YYRA 5AHUB 4LPHF 3WCAA 4HD1A 3PYAA 4QXSF 2Z4YA 3ACYA 1YQ7A 2ZCQA 3LG5A 1YYSA 3LK5A 1KIYA 5KSXF 3WCGA 2F89F 2J1OA 1HXAA 2J5CA 4GP2A 3WC9A 1YYUA 1JFGA 3WEIA 3M9UA 3SDTA 4H5CF 5ILJA 4LUUA 3SDRA 2Z50A 4NKFA 4MC0A 1N1ZA 1VG2A 3SDVA 3WSBA 2F9KF 3ZL6A 4KVIA 3OACA 3QQVA 3CKEA 3ZMCA 5A0KA 2ONGA 3TFPA 1UBYA 3N5HF 4KVYA 3BNXA 3LEEA 3P5PA 4OGUA 3ZCDA 3LSNA 5ILDA 4UMJA 3WE9A 1N23A 1WL2A 2PS4A 4LFGA 4XQTF 2QISA 3KROA 2J1PA 5DJVF 4LZ3A 4DWGA 3NF2A 3LOMA 3WJKA 5E8HA 1V4IA 5E8LA 3EZ3A 3LZ9A 5B0LA 5ILKA 4GAXA 5EAUA 5DZ2A 5JV2F 5ILYA 5ILHA 5B0MA 4LA6A 4NUAA 2P1CA 4MC3A 5AFXA 3TFVA 3AQBB 4XQRF 3SDQA 3P5RA 2F7MF 5AYPA 4DWBA 4LIXA 1ZW5A 4KKMA 2F8ZF 3OACB 4P0VA 5ILZA 4LTVA 3P8LA 4Q23A 1V4KA 2Z4ZA 1UBVA 2DH4A 3ICKA 4KWDA 3N46F 4RYPA 4LA5A 3PH7A 4L2XF 3LLWA 4KFAA 3DYFA 3TFNA 3N1VF 3WEFA 1RQIA 5DHIA 4KPJA 3KROB 1VG4A 4N1ZF 4JXNA 5IK9A 2AELA 2Q58A 3LDWA 5JUZF 1FPSA 3N1WF 3P41A 3Q1OA 4RXAA 5EATA 4LZ0A 3RMGA 5IN8A 2E8XA 2F8CF 1RQJA 5A0IA 2Z7HA 3M00A 3WCDA 3KRCA 5EROA 2E91A 4DHDA 4LFEA 3IPIA 2AZKA 5IKHA 2E90A 3WCIA 3Q2QA 5B02A 3W7FA 3APZA 3ZMBA 4E9ZA 3NRIA 2H8OA 4LPGF 1YHKA 5B0IA 5AELA 1N21A 1WL1A 2AZJA 1VG6A 4DXJA 3WJNA 4EA0A 4F62A 3N49F 3Q2ZA 3M0GA 3CP6A 4DEMF 4EA2A 3WCLA 1V4JA 3WJOA 5CG6A 2F94F 3TC1A 1EZFA 3IBAA 2Z7IA 3UCAA 2AZLA
chains in the Genus database with same CATH superfamily
3ICMA 3NPRA 5CG5A 4RXEA 3G4DA 3WEGA 3VJBA 1UBXA 2AEKA 2Z78A 1N22A 2E4OA 4KQSA 5JV1F 3M02A 4E9UA 1YV5A 4KQ5A 3ICZA 3KRCB 3WCHA 3ADZA 5I1UA 5HNAA 1DGPA 3WCCA 3DYGA 2PS7A 4N9UA 3AE0A 1YYQA 3OABA 3P8RA 3VJ8A 5HN8A 4GP1A 4H5DF 4LLSA 5EASA 1WL3A 3QKCA 2OPNA 3KRAA 4JYXA 2E95A 5B01A 4KUXA 4OKZA 5IL3A 4KK2A 3WEKA 4OKMA 5ER8A 1UBWA 2FORA 3VJEA 3ID0A 3Q30A 3EGTA 3N6KF 5A0JA 2RAHA 3EFQA 4DI5A 2ZCOA 3ICNA 4ZQ8A 5C05A 5JV0F 3S9VA 4NFIF 4P0WA 3WCBA 1HXGA 4KVDA 3N0GA 2E8VA 5H9DA 1YYTA 3LGKA 2O1OA 4RNQA 5B0JA 4LTZA 5B00A 4PVYF 3RBMA 3M01A 5IK0A 4LLTA 3ZOUA 2Q9ZA 3OABB 5JA0F 2E8TA 3N3DA 3WCFA 4QPFA 2Q80A 3KRAB 1RTRA 3LJIA 3NPKA 1HXCA 3N45F 4KPDA 4XQSF 3N3LF 5IK6A 3ASXA 1WKZA 4E1EA 4NG6A 3N0FA 2ZEVA 3WEJA 3AQ0A 4NFKF 2E8WA 1KIZA 3RYWA 5ERNA 2Q9YA 5B0KA 4F6XA 5B03A 3LVSA 2ONHA 3SAEA 2ZCRA 5DJPF 4RXDA 1HX9A 3AQCB 3KRFA 3WCJA 5IMIA 4PVXF 1N1BA 1DI1A 4KVWA 4RXCA 5DHKA 1VG3A 4LOBA 1N24A 2PS6A 3WSAA 4GA3A 2Z4XA 2Z4WA 4K10A 2I19A 3KRPA 5DW7A 1WY0A 3WCEA 2OA6A 2ZCSA 3VJCA 3LMDA 5DJRF 3ACXA 3ACWA 4FP4A 3SDUA 1PS1A 4F6VA 2OPMA 2E92A 3B7LA 2Z4VA 3DYHA 2VF6A 4NFJF 4NKEA 5IL8A 3VJ9A 3PDEA 2OGDA 5IM1A 5DGNF 5E8KA 5DIQF 4OMHA 3RYEA 2E94A 4MC8A 3V66A 3VJAA 5IKAA 3TS7A 1YHMA 3KRFB 4LXWA 4P0XA 3G4FA 4JZXA 2E93A 5ERMA 2E8UA 2AETA 2PS8A 3KBKA 1YHLA 5IMNA 3VJDA 3N5JF 4KQUA 2FTZA 5HN7A 4LFVF 1YJ4A 1WMWA 2PS5A 3KRPB 2ZEUA 3BNYA 3PKOA 4JVJF 1VG7A 4OMGA 5DGSF 5DGMF 1V4HA 4LZCA 1V4EA 2F92F 4JXYA 2EWGA 3OYRA 1JFAA 4DZWA 3V1VA 1HM4A 5ILIA 3KB9A 1N20A 3MAVA 4H5EF 3LGZB 5HN9A 3V1XA 4FJQA 3CC9A 4WK5A 3MZVA 3S4JA 4EA1A 1HM7A 1WL0A 5IVGA 5IMPA 3PYBA 3WEHA 4JZBA 2ZY1A 2Z52A 3WCMA 1YYRA 5AHUB 4LPHF 3WCAA 4HD1A 3PYAA 4QXSF 2Z4YA 3ACYA 1YQ7A 2ZCQA 3LG5A 1YYSA 3LK5A 1KIYA 5KSXF 3WCGA 2F89F 2J1OA 1HXAA 2J5CA 4GP2A 3WC9A 1YYUA 1JFGA 3WEIA 3M9UA 3SDTA 4H5CF 5ILJA 4LUUA 3SDRA 2Z50A 4NKFA 4MC0A 1N1ZA 1VG2A 3SDVA 3WSBA 2F9KF 3ZL6A 4KVIA 3OACA 3QQVA 3CKEA 3ZMCA 5A0KA 2ONGA 3TFPA 1UBYA 3N5HF 4KVYA 3BNXA 3LEEA 3P5PA 4OGUA 3ZCDA 3LSNA 5ILDA 4UMJA 3WE9A 1N23A 1WL2A 2PS4A 4LFGA 4XQTF 2QISA 3KROA 2J1PA 5DJVF 4LZ3A 4DWGA 3NF2A 3LOMA 3WJKA 5E8HA 1V4IA 5E8LA 3EZ3A 3LZ9A 5B0LA 5ILKA 4GAXA 5EAUA 5DZ2A 5JV2F 5ILYA 5ILHA 5B0MA 4LA6A 4NUAA 2P1CA 4MC3A 5AFXA 3TFVA 3AQBB 4XQRF 3SDQA 3P5RA 2F7MF 5AYPA 4DWBA 4LIXA 1ZW5A 4KKMA 2F8ZF 3OACB 4P0VA 5ILZA 4LTVA 3P8LA 4Q23A 1V4KA 2Z4ZA 1UBVA 2DH4A 3ICKA 4KWDA 3N46F 4RYPA 4LA5A 3PH7A 4L2XF 3LLWA 4KFAA 3DYFA 3TFNA 3N1VF 3WEFA 1RQIA 5DHIA 4KPJA 3KROB 1VG4A 4N1ZF 4JXNA 5IK9A 2AELA 2Q58A 3LDWA 5JUZF 1FPSA 3N1WF 3P41A 3Q1OA 4RXAA 5EATA 4LZ0A 3RMGA 5IN8A 2E8XA 2F8CF 1RQJA 5A0IA 2Z7HA 3M00A 3WCDA 3KRCA 5EROA 2E91A 4DHDA 4LFEA 3IPIA 2AZKA 5IKHA 2E90A 3WCIA 3Q2QA 5B02A 3W7FA 3APZA 3ZMBA 4E9ZA 3NRIA 2H8OA 4LPGF 1YHKA 5B0IA 5AELA 1N21A 1WL1A 2AZJA 1VG6A 4DXJA 3WJNA 4EA0A 4F62A 3N49F 3Q2ZA 3M0GA 3CP6A 4DEMF 4EA2A 3WCLA 1V4JA 3WJOA 5CG6A 2F94F 3TC1A 1EZFA 3IBAA 2Z7IA 3UCAA 2AZLA
chains in the Genus database with same CATH topology
3ICMA 3NPRA 5CG5A 4RXEA 3G4DA 3WEGA 3VJBA 1UBXA 2AEKA 2Z78A 1N22A 2E4OA 4KQSA 5JV1F 3M02A 4E9UA 1YV5A 4KQ5A 3ICZA 3KRCB 3WCHA 3ADZA 5I1UA 5HNAA 1DGPA 3WCCA 3DYGA 2PS7A 4N9UA 3AE0A 1YYQA 3OABA 3P8RA 3VJ8A 5HN8A 4GP1A 4H5DF 4LLSA 5EASA 1WL3A 3QKCA 2OPNA 3KRAA 4JYXA 2E95A 5B01A 4KUXA 4OKZA 5IL3A 4KK2A 3WEKA 4OKMA 5ER8A 1UBWA 2FORA 3VJEA 3ID0A 3Q30A 3EGTA 3N6KF 5A0JA 2RAHA 3EFQA 4DI5A 2ZCOA 3ICNA 4ZQ8A 5C05A 5JV0F 3S9VA 4NFIF 4P0WA 3WCBA 1HXGA 4KVDA 3N0GA 2E8VA 5H9DA 1YYTA 3LGKA 2O1OA 4RNQA 5B0JA 4LTZA 5B00A 4PVYF 3RBMA 3M01A 5IK0A 4LLTA 3ZOUA 2Q9ZA 3OABB 5JA0F 2E8TA 3N3DA 3WCFA 4QPFA 2Q80A 3KRAB 1RTRA 3LJIA 3NPKA 1HXCA 3N45F 4KPDA 4XQSF 3N3LF 5IK6A 3ASXA 1WKZA 4E1EA 4NG6A 3N0FA 2ZEVA 3WEJA 3AQ0A 4NFKF 2E8WA 1KIZA 3RYWA 5ERNA 2Q9YA 5B0KA 4F6XA 5B03A 3LVSA 2ONHA 3SAEA 2ZCRA 5DJPF 4RXDA 1HX9A 3AQCB 3KRFA 3WCJA 5IMIA 4PVXF 1N1BA 1DI1A 4KVWA 4RXCA 5DHKA 1VG3A 4LOBA 1N24A 2PS6A 3WSAA 4GA3A 2Z4XA 2Z4WA 4K10A 2I19A 3KRPA 5DW7A 1WY0A 3WCEA 2OA6A 2ZCSA 3VJCA 3LMDA 5DJRF 3ACXA 3ACWA 4FP4A 3SDUA 1PS1A 4F6VA 2OPMA 2E92A 3B7LA 2Z4VA 3DYHA 2VF6A 4NFJF 4NKEA 5IL8A 3VJ9A 3PDEA 2OGDA 5IM1A 5DGNF 5E8KA 5DIQF 4OMHA 3RYEA 2E94A 4MC8A 3V66A 3VJAA 5IKAA 3TS7A 1YHMA 3KRFB 4LXWA 4P0XA 3G4FA 4JZXA 2E93A 5ERMA 2E8UA 2AETA 2PS8A 3KBKA 1YHLA 5IMNA 3VJDA 3N5JF 4KQUA 2FTZA 5HN7A 4LFVF 1YJ4A 1WMWA 2PS5A 3KRPB 2ZEUA 3BNYA 3PKOA 4JVJF 1VG7A 4OMGA 5DGSF 5DGMF 1V4HA 4LZCA 1V4EA 2F92F 4JXYA 2EWGA 3OYRA 1JFAA 4DZWA 3V1VA 1HM4A 5ILIA 3KB9A 1N20A 3MAVA 4H5EF 3LGZB 5HN9A 3V1XA 4FJQA 3CC9A 4WK5A 3MZVA 3S4JA 4EA1A 1HM7A 1WL0A 5IVGA 5IMPA 3PYBA 3WEHA 4JZBA 2ZY1A 2Z52A 3WCMA 1YYRA 5AHUB 4LPHF 3WCAA 4HD1A 3PYAA 4QXSF 2Z4YA 3ACYA 1YQ7A 2ZCQA 3LG5A 1YYSA 3LK5A 1KIYA 5KSXF 3WCGA 2F89F 2J1OA 1HXAA 2J5CA 4GP2A 3WC9A 1YYUA 1JFGA 3WEIA 3M9UA 3SDTA 4H5CF 5ILJA 4LUUA 3SDRA 2Z50A 4NKFA 4MC0A 1N1ZA 1VG2A 3SDVA 3WSBA 2F9KF 3ZL6A 4KVIA 3OACA 3QQVA 3CKEA 3ZMCA 5A0KA 2ONGA 3TFPA 1UBYA 3N5HF 4KVYA 3BNXA 3LEEA 3P5PA 4OGUA 3ZCDA 3LSNA 5ILDA 4UMJA 3WE9A 1N23A 1WL2A 2PS4A 4LFGA 4XQTF 2QISA 3KROA 2J1PA 5DJVF 4LZ3A 4DWGA 3NF2A 3LOMA 3WJKA 5E8HA 1V4IA 5E8LA 3EZ3A 3LZ9A 5B0LA 5ILKA 4GAXA 5EAUA 5DZ2A 5JV2F 5ILYA 5ILHA 5B0MA 4LA6A 4NUAA 2P1CA 4MC3A 5AFXA 3TFVA 3AQBB 4XQRF 3SDQA 3P5RA 2F7MF 5AYPA 4DWBA 4LIXA 1ZW5A 4KKMA 2F8ZF 3OACB 4P0VA 5ILZA 4LTVA 3P8LA 4Q23A 1V4KA 2Z4ZA 1UBVA 2DH4A 3ICKA 4KWDA 3N46F 4RYPA 4LA5A 3PH7A 4L2XF 3LLWA 4KFAA 3DYFA 3TFNA 3N1VF 3WEFA 1RQIA 5DHIA 4KPJA 3KROB 1VG4A 4N1ZF 4JXNA 5IK9A 2AELA 2Q58A 3LDWA 5JUZF 1FPSA 3N1WF 3P41A 3Q1OA 4RXAA 5EATA 4LZ0A 3RMGA 5IN8A 2E8XA 2F8CF 1RQJA 5A0IA 2Z7HA 3M00A 3WCDA 3KRCA 5EROA 2E91A 4DHDA 4LFEA 3IPIA 2AZKA 5IKHA 2E90A 3WCIA 3Q2QA 5B02A 3W7FA 3APZA 3ZMBA 4E9ZA 3NRIA 2H8OA 4LPGF 1YHKA 5B0IA 5AELA 1N21A 1WL1A 2AZJA 1VG6A 4DXJA 3WJNA 4EA0A 4F62A 3N49F 3Q2ZA 3M0GA 3CP6A 4DEMF 4EA2A 3WCLA 1V4JA 3WJOA 5CG6A 2F94F 3TC1A 1EZFA 3IBAA 2Z7IA 3UCAA 2AZLA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3ICM A;  3NPR A;  5CG5 A;  4RXE A;  3G4D A;  3WEG A;  3VJB A;  1UBX A;  2AEK A;  2Z78 A;  1N22 A;  2E4O A;  4KQS A;  5JV1 F;  3M02 A;  4E9U A;  1YV5 A;  4KQ5 A;  3ICZ A;  3KRC B;  3WCH A;  3ADZ A;  5I1U A;  5HNA A;  1DGP A;  3WCC A;  3DYG A;  2PS7 A;  4N9U A;  3AE0 A;  1YYQ A;  3OAB A;  3P8R A;  3VJ8 A;  5HN8 A;  4GP1 A;  4H5D F;  4LLS A;  5EAS A;  1WL3 A;  3QKC A;  2OPN A;  3KRA A;  4JYX A;  2E95 A;  5B01 A;  4KUX A;  4OKZ A;  5IL3 A;  4KK2 A;  3WEK A;  4OKM A;  5ER8 A;  1UBW A;  2FOR A;  3VJE A;  3ID0 A;  3Q30 A;  3EGT A;  3N6K F;  5A0J A;  2RAH A;  3EFQ A;  4DI5 A;  2ZCO A;  3ICN A;  4ZQ8 A;  5C05 A;  5JV0 F;  3S9V A;  4NFI F;  4P0W A;  3WCB A;  1HXG A;  4KVD A;  3N0G A;  2E8V A;  5H9D A;  1YYT A;  3LGK A;  2O1O A;  4RNQ A;  5B0J A;  4LTZ A;  5B00 A;  4PVY F;  3RBM A;  3M01 A;  5IK0 A;  4LLT A;  3ZOU A;  2Q9Z A;  3OAB B;  5JA0 F;  2E8T A;  3N3D A;  3WCF A;  4QPF A;  2Q80 A;  3KRA B;  1RTR A;  3LJI A;  3NPK A;  1HXC A;  3N45 F;  4KPD A;  4XQS F;  3N3L F;  5IK6 A;  3ASX A;  1WKZ A;  4E1E A;  4NG6 A;  3N0F A;  2ZEV A;  3WEJ A;  3AQ0 A;  4NFK F;  2E8W A;  1KIZ A;  3RYW A;  5ERN A;  2Q9Y A;  5B0K A;  4F6X A;  5B03 A;  3LVS A;  2ONH A;  3SAE A;  2ZCR A;  5DJP F;  4RXD A;  1HX9 A;  3AQC B;  3KRF A;  3WCJ A;  5IMI A;  4PVX F;  1N1B A;  1DI1 A;  4KVW A;  4RXC A;  5DHK A;  1VG3 A;  4LOB A;  1N24 A;  2PS6 A;  3WSA A;  4GA3 A;  2Z4X A;  2Z4W A;  4K10 A;  2I19 A;  3KRP A;  5DW7 A;  1WY0 A;  3WCE A;  2OA6 A;  2ZCS A;  3VJC A;  3LMD A;  5DJR F;  3ACX A;  3ACW A;  4FP4 A;  3SDU A;  1PS1 A;  4F6V A;  2OPM A;  2E92 A;  3B7L A;  2Z4V A;  3DYH A;  2VF6 A;  4NFJ F;  4NKE A;  5IL8 A;  3VJ9 A;  3PDE A;  2OGD A;  5IM1 A;  5DGN F;  5E8K A;  5DIQ F;  4OMH A;  3RYE A;  2E94 A;  4MC8 A;  3V66 A;  3VJA A;  5IKA A;  3TS7 A;  1YHM A;  3KRF B;  4LXW A;  4P0X A;  3G4F A;  4JZX A;  2E93 A;  5ERM A;  2E8U A;  2AET A;  2PS8 A;  3KBK A;  1YHL A;  5IMN A;  3VJD A;  3N5J F;  4KQU A;  2FTZ A;  5HN7 A;  4LFV F;  1YJ4 A;  1WMW A;  2PS5 A;  3KRP B;  2ZEU A;  3BNY A;  3PKO A;  4JVJ F;  1VG7 A;  4OMG A;  5DGS F;  5DGM F;  1V4H A;  4LZC A;  1V4E A;  2F92 F;  4JXY A;  2EWG A;  3OYR A;  1JFA A;  4DZW A;  3V1V A;  1HM4 A;  5ILI A;  3KB9 A;  1N20 A;  3MAV A;  4H5E F;  3LGZ B;  5HN9 A;  3V1X A;  4FJQ A;  3CC9 A;  4WK5 A;  3MZV A;  3S4J A;  4EA1 A;  1HM7 A;  1WL0 A;  5IVG A;  5IMP A;  3PYB A;  3WEH A;  4JZB A;  2ZY1 A;  2Z52 A;  3WCM A;  1YYR A;  5AHU B;  4LPH F;  3WCA A;  4HD1 A;  3PYA A;  4QXS F;  2Z4Y A;  3ACY A;  1YQ7 A;  2ZCQ A;  3LG5 A;  1YYS A;  3LK5 A;  1KIY A;  5KSX F;  3WCG A;  2F89 F;  2J1O A;  1HXA A;  2J5C A;  4GP2 A;  3WC9 A;  1YYU A;  1JFG A;  3WEI A;  3M9U A;  3SDT A;  4H5C F;  5ILJ A;  4LUU A;  3SDR A;  2Z50 A;  4NKF A;  4MC0 A;  1N1Z A;  1VG2 A;  3SDV A;  3WSB A;  2F9K F;  3ZL6 A;  4KVI A;  3OAC A;  3QQV A;  3CKE A;  3ZMC A;  5A0K A;  2ONG A;  3TFP A;  1UBY A;  3N5H F;  4KVY A;  3BNX A;  3LEE A;  3P5P A;  4OGU A;  3ZCD A;  3LSN A;  5ILD A;  4UMJ A;  3WE9 A;  1N23 A;  1WL2 A;  2PS4 A;  4LFG A;  4XQT F;  2QIS A;  3KRO A;  2J1P A;  5DJV F;  4LZ3 A;  4DWG A;  3NF2 A;  3LOM A;  3WJK A;  5E8H A;  1V4I A;  5E8L A;  3EZ3 A;  3LZ9 A;  5B0L A;  5ILK A;  4GAX A;  5EAU A;  5DZ2 A;  5JV2 F;  5ILY A;  5ILH A;  5B0M A;  4LA6 A;  4NUA A;  2P1C A;  4MC3 A;  5AFX A;  3TFV A;  3AQB B;  4XQR F;  3SDQ A;  3P5R A;  2F7M F;  5AYP A;  4DWB A;  4LIX A;  1ZW5 A;  4KKM A;  2F8Z F;  3OAC B;  4P0V A;  5ILZ A;  4LTV A;  3P8L A;  4Q23 A;  1V4K A;  2Z4Z A;  1UBV A;  2DH4 A;  3ICK A;  4KWD A;  3N46 F;  4RYP A;  4LA5 A;  3PH7 A;  4L2X F;  3LLW A;  4KFA A;  3DYF A;  3TFN A;  3N1V F;  3WEF A;  1RQI A;  5DHI A;  4KPJ A;  3KRO B;  1VG4 A;  4N1Z F;  4JXN A;  5IK9 A;  2AEL A;  2Q58 A;  3LDW A;  5JUZ F;  1FPS A;  3N1W F;  3P41 A;  3Q1O A;  4RXA A;  5EAT A;  4LZ0 A;  3RMG A;  5IN8 A;  2E8X A;  2F8C F;  1RQJ A;  5A0I A;  2Z7H A;  3M00 A;  3WCD A;  3KRC A;  5ERO A;  2E91 A;  4DHD A;  4LFE A;  3IPI A;  2AZK A;  5IKH A;  2E90 A;  3WCI A;  3Q2Q A;  5B02 A;  3W7F A;  3APZ A;  3ZMB A;  4E9Z A;  3NRI A;  2H8O A;  4LPG F;  1YHK A;  5B0I A;  5AEL A;  1N21 A;  1WL1 A;  2AZJ A;  1VG6 A;  4DXJ A;  3WJN A;  4EA0 A;  4F62 A;  3N49 F;  3Q2Z A;  3M0G A;  3CP6 A;  4DEM F;  4EA2 A;  3WCL A;  1V4J A;  3WJO A;  5CG6 A;  2F94 F;  3TC1 A;  1EZF A;  3IBA A;  2Z7I A;  3UCA A;  2AZL A; 
#chains in the Genus database with same CATH topology
 3ICM A;  3NPR A;  5CG5 A;  4RXE A;  3G4D A;  3WEG A;  3VJB A;  1UBX A;  2AEK A;  2Z78 A;  1N22 A;  2E4O A;  4KQS A;  5JV1 F;  3M02 A;  4E9U A;  1YV5 A;  4KQ5 A;  3ICZ A;  3KRC B;  3WCH A;  3ADZ A;  5I1U A;  5HNA A;  1DGP A;  3WCC A;  3DYG A;  2PS7 A;  4N9U A;  3AE0 A;  1YYQ A;  3OAB A;  3P8R A;  3VJ8 A;  5HN8 A;  4GP1 A;  4H5D F;  4LLS A;  5EAS A;  1WL3 A;  3QKC A;  2OPN A;  3KRA A;  4JYX A;  2E95 A;  5B01 A;  4KUX A;  4OKZ A;  5IL3 A;  4KK2 A;  3WEK A;  4OKM A;  5ER8 A;  1UBW A;  2FOR A;  3VJE A;  3ID0 A;  3Q30 A;  3EGT A;  3N6K F;  5A0J A;  2RAH A;  3EFQ A;  4DI5 A;  2ZCO A;  3ICN A;  4ZQ8 A;  5C05 A;  5JV0 F;  3S9V A;  4NFI F;  4P0W A;  3WCB A;  1HXG A;  4KVD A;  3N0G A;  2E8V A;  5H9D A;  1YYT A;  3LGK A;  2O1O A;  4RNQ A;  5B0J A;  4LTZ A;  5B00 A;  4PVY F;  3RBM A;  3M01 A;  5IK0 A;  4LLT A;  3ZOU A;  2Q9Z A;  3OAB B;  5JA0 F;  2E8T A;  3N3D A;  3WCF A;  4QPF A;  2Q80 A;  3KRA B;  1RTR A;  3LJI A;  3NPK A;  1HXC A;  3N45 F;  4KPD A;  4XQS F;  3N3L F;  5IK6 A;  3ASX A;  1WKZ A;  4E1E A;  4NG6 A;  3N0F A;  2ZEV A;  3WEJ A;  3AQ0 A;  4NFK F;  2E8W A;  1KIZ A;  3RYW A;  5ERN A;  2Q9Y A;  5B0K A;  4F6X A;  5B03 A;  3LVS A;  2ONH A;  3SAE A;  2ZCR A;  5DJP F;  4RXD A;  1HX9 A;  3AQC B;  3KRF A;  3WCJ A;  5IMI A;  4PVX F;  1N1B A;  1DI1 A;  4KVW A;  4RXC A;  5DHK A;  1VG3 A;  4LOB A;  1N24 A;  2PS6 A;  3WSA A;  4GA3 A;  2Z4X A;  2Z4W A;  4K10 A;  2I19 A;  3KRP A;  5DW7 A;  1WY0 A;  3WCE A;  2OA6 A;  2ZCS A;  3VJC A;  3LMD A;  5DJR F;  3ACX A;  3ACW A;  4FP4 A;  3SDU A;  1PS1 A;  4F6V A;  2OPM A;  2E92 A;  3B7L A;  2Z4V A;  3DYH A;  2VF6 A;  4NFJ F;  4NKE A;  5IL8 A;  3VJ9 A;  3PDE A;  2OGD A;  5IM1 A;  5DGN F;  5E8K A;  5DIQ F;  4OMH A;  3RYE A;  2E94 A;  4MC8 A;  3V66 A;  3VJA A;  5IKA A;  3TS7 A;  1YHM A;  3KRF B;  4LXW A;  4P0X A;  3G4F A;  4JZX A;  2E93 A;  5ERM A;  2E8U A;  2AET A;  2PS8 A;  3KBK A;  1YHL A;  5IMN A;  3VJD A;  3N5J F;  4KQU A;  2FTZ A;  5HN7 A;  4LFV F;  1YJ4 A;  1WMW A;  2PS5 A;  3KRP B;  2ZEU A;  3BNY A;  3PKO A;  4JVJ F;  1VG7 A;  4OMG A;  5DGS F;  5DGM F;  1V4H A;  4LZC A;  1V4E A;  2F92 F;  4JXY A;  2EWG A;  3OYR A;  1JFA A;  4DZW A;  3V1V A;  1HM4 A;  5ILI A;  3KB9 A;  1N20 A;  3MAV A;  4H5E F;  3LGZ B;  5HN9 A;  3V1X A;  4FJQ A;  3CC9 A;  4WK5 A;  3MZV A;  3S4J A;  4EA1 A;  1HM7 A;  1WL0 A;  5IVG A;  5IMP A;  3PYB A;  3WEH A;  4JZB A;  2ZY1 A;  2Z52 A;  3WCM A;  1YYR A;  5AHU B;  4LPH F;  3WCA A;  4HD1 A;  3PYA A;  4QXS F;  2Z4Y A;  3ACY A;  1YQ7 A;  2ZCQ A;  3LG5 A;  1YYS A;  3LK5 A;  1KIY A;  5KSX F;  3WCG A;  2F89 F;  2J1O A;  1HXA A;  2J5C A;  4GP2 A;  3WC9 A;  1YYU A;  1JFG A;  3WEI A;  3M9U A;  3SDT A;  4H5C F;  5ILJ A;  4LUU A;  3SDR A;  2Z50 A;  4NKF A;  4MC0 A;  1N1Z A;  1VG2 A;  3SDV A;  3WSB A;  2F9K F;  3ZL6 A;  4KVI A;  3OAC A;  3QQV A;  3CKE A;  3ZMC A;  5A0K A;  2ONG A;  3TFP A;  1UBY A;  3N5H F;  4KVY A;  3BNX A;  3LEE A;  3P5P A;  4OGU A;  3ZCD A;  3LSN A;  5ILD A;  4UMJ A;  3WE9 A;  1N23 A;  1WL2 A;  2PS4 A;  4LFG A;  4XQT F;  2QIS A;  3KRO A;  2J1P A;  5DJV F;  4LZ3 A;  4DWG A;  3NF2 A;  3LOM A;  3WJK A;  5E8H A;  1V4I A;  5E8L A;  3EZ3 A;  3LZ9 A;  5B0L A;  5ILK A;  4GAX A;  5EAU A;  5DZ2 A;  5JV2 F;  5ILY A;  5ILH A;  5B0M A;  4LA6 A;  4NUA A;  2P1C A;  4MC3 A;  5AFX A;  3TFV A;  3AQB B;  4XQR F;  3SDQ A;  3P5R A;  2F7M F;  5AYP A;  4DWB A;  4LIX A;  1ZW5 A;  4KKM A;  2F8Z F;  3OAC B;  4P0V A;  5ILZ A;  4LTV A;  3P8L A;  4Q23 A;  1V4K A;  2Z4Z A;  1UBV A;  2DH4 A;  3ICK A;  4KWD A;  3N46 F;  4RYP A;  4LA5 A;  3PH7 A;  4L2X F;  3LLW A;  4KFA A;  3DYF A;  3TFN A;  3N1V F;  3WEF A;  1RQI A;  5DHI A;  4KPJ A;  3KRO B;  1VG4 A;  4N1Z F;  4JXN A;  5IK9 A;  2AEL A;  2Q58 A;  3LDW A;  5JUZ F;  1FPS A;  3N1W F;  3P41 A;  3Q1O A;  4RXA A;  5EAT A;  4LZ0 A;  3RMG A;  5IN8 A;  2E8X A;  2F8C F;  1RQJ A;  5A0I A;  2Z7H A;  3M00 A;  3WCD A;  3KRC A;  5ERO A;  2E91 A;  4DHD A;  4LFE A;  3IPI A;  2AZK A;  5IKH A;  2E90 A;  3WCI A;  3Q2Q A;  5B02 A;  3W7F A;  3APZ A;  3ZMB A;  4E9Z A;  3NRI A;  2H8O A;  4LPG F;  1YHK A;  5B0I A;  5AEL A;  1N21 A;  1WL1 A;  2AZJ A;  1VG6 A;  4DXJ A;  3WJN A;  4EA0 A;  4F62 A;  3N49 F;  3Q2Z A;  3M0G A;  3CP6 A;  4DEM F;  4EA2 A;  3WCL A;  1V4J A;  3WJO A;  5CG6 A;  2F94 F;  3TC1 A;  1EZF A;  3IBA A;  2Z7I A;  3UCA A;  2AZL A; 
#chains in the Genus database with same CATH homology
 3ICM A;  3NPR A;  5CG5 A;  4RXE A;  3G4D A;  3WEG A;  3VJB A;  1UBX A;  2AEK A;  2Z78 A;  1N22 A;  2E4O A;  4KQS A;  5JV1 F;  3M02 A;  4E9U A;  1YV5 A;  4KQ5 A;  3ICZ A;  3KRC B;  3WCH A;  3ADZ A;  5I1U A;  5HNA A;  1DGP A;  3WCC A;  3DYG A;  2PS7 A;  4N9U A;  3AE0 A;  1YYQ A;  3OAB A;  3P8R A;  3VJ8 A;  5HN8 A;  4GP1 A;  4H5D F;  4LLS A;  5EAS A;  1WL3 A;  3QKC A;  2OPN A;  3KRA A;  4JYX A;  2E95 A;  5B01 A;  4KUX A;  4OKZ A;  5IL3 A;  4KK2 A;  3WEK A;  4OKM A;  5ER8 A;  1UBW A;  2FOR A;  3VJE A;  3ID0 A;  3Q30 A;  3EGT A;  3N6K F;  5A0J A;  2RAH A;  3EFQ A;  4DI5 A;  2ZCO A;  3ICN A;  4ZQ8 A;  5C05 A;  5JV0 F;  3S9V A;  4NFI F;  4P0W A;  3WCB A;  1HXG A;  4KVD A;  3N0G A;  2E8V A;  5H9D A;  1YYT A;  3LGK A;  2O1O A;  4RNQ A;  5B0J A;  4LTZ A;  5B00 A;  4PVY F;  3RBM A;  3M01 A;  5IK0 A;  4LLT A;  3ZOU A;  2Q9Z A;  3OAB B;  5JA0 F;  2E8T A;  3N3D A;  3WCF A;  4QPF A;  2Q80 A;  3KRA B;  1RTR A;  3LJI A;  3NPK A;  1HXC A;  3N45 F;  4KPD A;  4XQS F;  3N3L F;  5IK6 A;  3ASX A;  1WKZ A;  4E1E A;  4NG6 A;  3N0F A;  2ZEV A;  3WEJ A;  3AQ0 A;  4NFK F;  2E8W A;  1KIZ A;  3RYW A;  5ERN A;  2Q9Y A;  5B0K A;  4F6X A;  5B03 A;  3LVS A;  2ONH A;  3SAE A;  2ZCR A;  5DJP F;  4RXD A;  1HX9 A;  3AQC B;  3KRF A;  3WCJ A;  5IMI A;  4PVX F;  1N1B A;  1DI1 A;  4KVW A;  4RXC A;  5DHK A;  1VG3 A;  4LOB A;  1N24 A;  2PS6 A;  3WSA A;  4GA3 A;  2Z4X A;  2Z4W A;  4K10 A;  2I19 A;  3KRP A;  5DW7 A;  1WY0 A;  3WCE A;  2OA6 A;  2ZCS A;  3VJC A;  3LMD A;  5DJR F;  3ACX A;  3ACW A;  4FP4 A;  3SDU A;  1PS1 A;  4F6V A;  2OPM A;  2E92 A;  3B7L A;  2Z4V A;  3DYH A;  2VF6 A;  4NFJ F;  4NKE A;  5IL8 A;  3VJ9 A;  3PDE A;  2OGD A;  5IM1 A;  5DGN F;  5E8K A;  5DIQ F;  4OMH A;  3RYE A;  2E94 A;  4MC8 A;  3V66 A;  3VJA A;  5IKA A;  3TS7 A;  1YHM A;  3KRF B;  4LXW A;  4P0X A;  3G4F A;  4JZX A;  2E93 A;  5ERM A;  2E8U A;  2AET A;  2PS8 A;  3KBK A;  1YHL A;  5IMN A;  3VJD A;  3N5J F;  4KQU A;  2FTZ A;  5HN7 A;  4LFV F;  1YJ4 A;  1WMW A;  2PS5 A;  3KRP B;  2ZEU A;  3BNY A;  3PKO A;  4JVJ F;  1VG7 A;  4OMG A;  5DGS F;  5DGM F;  1V4H A;  4LZC A;  1V4E A;  2F92 F;  4JXY A;  2EWG A;  3OYR A;  1JFA A;  4DZW A;  3V1V A;  1HM4 A;  5ILI A;  3KB9 A;  1N20 A;  3MAV A;  4H5E F;  3LGZ B;  5HN9 A;  3V1X A;  4FJQ A;  3CC9 A;  4WK5 A;  3MZV A;  3S4J A;  4EA1 A;  1HM7 A;  1WL0 A;  5IVG A;  5IMP A;  3PYB A;  3WEH A;  4JZB A;  2ZY1 A;  2Z52 A;  3WCM A;  1YYR A;  5AHU B;  4LPH F;  3WCA A;  4HD1 A;  3PYA A;  4QXS F;  2Z4Y A;  3ACY A;  1YQ7 A;  2ZCQ A;  3LG5 A;  1YYS A;  3LK5 A;  1KIY A;  5KSX F;  3WCG A;  2F89 F;  2J1O A;  1HXA A;  2J5C A;  4GP2 A;  3WC9 A;  1YYU A;  1JFG A;  3WEI A;  3M9U A;  3SDT A;  4H5C F;  5ILJ A;  4LUU A;  3SDR A;  2Z50 A;  4NKF A;  4MC0 A;  1N1Z A;  1VG2 A;  3SDV A;  3WSB A;  2F9K F;  3ZL6 A;  4KVI A;  3OAC A;  3QQV A;  3CKE A;  3ZMC A;  5A0K A;  2ONG A;  3TFP A;  1UBY A;  3N5H F;  4KVY A;  3BNX A;  3LEE A;  3P5P A;  4OGU A;  3ZCD A;  3LSN A;  5ILD A;  4UMJ A;  3WE9 A;  1N23 A;  1WL2 A;  2PS4 A;  4LFG A;  4XQT F;  2QIS A;  3KRO A;  2J1P A;  5DJV F;  4LZ3 A;  4DWG A;  3NF2 A;  3LOM A;  3WJK A;  5E8H A;  1V4I A;  5E8L A;  3EZ3 A;  3LZ9 A;  5B0L A;  5ILK A;  4GAX A;  5EAU A;  5DZ2 A;  5JV2 F;  5ILY A;  5ILH A;  5B0M A;  4LA6 A;  4NUA A;  2P1C A;  4MC3 A;  5AFX A;  3TFV A;  3AQB B;  4XQR F;  3SDQ A;  3P5R A;  2F7M F;  5AYP A;  4DWB A;  4LIX A;  1ZW5 A;  4KKM A;  2F8Z F;  3OAC B;  4P0V A;  5ILZ A;  4LTV A;  3P8L A;  4Q23 A;  1V4K A;  2Z4Z A;  1UBV A;  2DH4 A;  3ICK A;  4KWD A;  3N46 F;  4RYP A;  4LA5 A;  3PH7 A;  4L2X F;  3LLW A;  4KFA A;  3DYF A;  3TFN A;  3N1V F;  3WEF A;  1RQI A;  5DHI A;  4KPJ A;  3KRO B;  1VG4 A;  4N1Z F;  4JXN A;  5IK9 A;  2AEL A;  2Q58 A;  3LDW A;  5JUZ F;  1FPS A;  3N1W F;  3P41 A;  3Q1O A;  4RXA A;  5EAT A;  4LZ0 A;  3RMG A;  5IN8 A;  2E8X A;  2F8C F;  1RQJ A;  5A0I A;  2Z7H A;  3M00 A;  3WCD A;  3KRC A;  5ERO A;  2E91 A;  4DHD A;  4LFE A;  3IPI A;  2AZK A;  5IKH A;  2E90 A;  3WCI A;  3Q2Q A;  5B02 A;  3W7F A;  3APZ A;  3ZMB A;  4E9Z A;  3NRI A;  2H8O A;  4LPG F;  1YHK A;  5B0I A;  5AEL A;  1N21 A;  1WL1 A;  2AZJ A;  1VG6 A;  4DXJ A;  3WJN A;  4EA0 A;  4F62 A;  3N49 F;  3Q2Z A;  3M0G A;  3CP6 A;  4DEM F;  4EA2 A;  3WCL A;  1V4J A;  3WJO A;  5CG6 A;  2F94 F;  3TC1 A;  1EZF A;  3IBA A;  2Z7I A;  3UCA A;  2AZL A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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