3WC9A

The complex structure of hssqs wtih ligand, fspp
Total Genus 135
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
135
sequence length
333
structure length
333
Chain Sequence
LSSSLKTCYKYLNQTSRSFAAVIQALDGEMRNAVCIFYLVLRALDTLEDDMTISVEKKVPLLHNFHSFLYQPDWRFMESKEKDRQVLEDFPTISLEFRNLAEKYQTVIADICRRMGIGMAEFLDKHVTSEQEWDKYCHYVAGLVGIGLSRLFSASEFEDPLVGEDTERANSMGLFLQKTNIIRDYLEDQQGGREFWPQEVWSRYVKKLGDFALPENIDLAVQCLNELITNALHHIPDVITYLSRLRNQSVFNFCAIPQVMAIATLAACYNNQQVFKGAVLIRLGQAVTLMMDATNMPAVKAIIYQYMEEIYHRIPDSNPSSSKTRQIISTIRT
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Squalene synthase as a target for Chagas disease therapeutics.
pubmed doi rcsb
molecule tags Transferase
source organism Homo sapiens
molecule keywords Squalene synthase
total genus 135
structure length 333
sequence length 333
chains with identical sequence B, C, D, E, F
ec nomenclature ec 2.5.1.21: Squalene synthase.
pdb deposition date 2013-05-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00494 SQS_PSY Squalene/phytoene synthase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.600.10 Mainly Alpha Orthogonal Bundle Farnesyl Diphosphate Synthase Farnesyl Diphosphate Synthase 3wc9A00
5ILYA 2FORA 2E93A 3B7LA 4OKZA 5ILJA 5DIQF 2EWGA 3LMDA 2Z4YA 2Z52A 3WCLA 3N3DA 3CP6A 3P5PA 4KVWA 4LFEA 2PS5A 3WJOA 3UCAA 2PS6A 1WL2A 4JVJF 4DWGA 5CG6A 3V66A 3ACWA 1N20A 4RNQA 3MAVA 3KBKA 2DH4A 5B0MA 4LXWA 5IL3A 1WL3A 2E90A 4LZCA 4DHDA 5ILKA 4MC0A 2F94F 1UBXA 4KFAA 1YHLA 3N46F 4LZ3A 3VJDA 4LUUA 3LGKA 3WCBA 5IMIA 5JA0F 3KRAB 2P1CA 2E8UA 5IK0A 1PS1A 3EZ3A 4OMHA 4XQSF 1UBVA 1YYRA 5EATA 3Q1OA 1UBWA 2VF6A 2Z4XA 3P8RA 3Q30A 3N1WF 1N24A 3QQVA 4KQ5A 3ICKA 3PKOA 4H5CF 4KPDA 2AZKA 4H5DF 4RXDA 1RQJA 3W7FA 3ACYA 2QISA 5JUZF 3ADZA 5IK9A 2ZCRA 2RAHA 3ICMA 4KVDA 4EA1A 4LFVF 4NUAA 5B0KA 5EAUA 1KIYA 4LFGA 3VJ9A 3IBAA 3OABA 3ZL6A 3RBMA 4DWBA 2Z4ZA 3ZOUA 1WL1A 3KROA 3LVSA 3ZCDA 5HNAA 3LGZB 3OABB 3WCFA 3NPKA 2E94A 2Q9ZA 5IM1A 2OPMA 2PS7A 2ZY1A 4WK5A 5IK6A 2OGDA 1N21A 4LPHF 3M02A 3RMGA 4XQTF 1YYTA 3AQ0A 3N5HF 2OPNA 4F62A 3SDVA 4Q23A 2Z78A 2E8XA 3SDQA 4JZBA 3WCDA 3SDUA 4OKMA 5E8KA 3WEHA 3M0GA 2E8TA 5IKAA 4E1EA 3M9UA 3DYFA 3OYRA 2AZLA 4LLSA 4E9ZA 4GAXA 3KRPA 1YJ4A 2J1PA 4LTVA 4PVYF 2ONHA 4EA0A 1VG4A 3BNYA 5ER8A 1VG2A 4UMJA 2Q9YA 5KSXF 2Z50A 3VJ8A 4KVYA 4LOBA 5HN9A 1VG7A 3WCJA 3ACXA 3S9VA 1YHKA 4MC3A 4JZXA 3EGTA 3WEGA 3VJAA 3KRFA 4LLTA 2Z4VA 4KUXA 4NFIF 1WMWA 3WEKA 2F9KF 4NG6A 1YYSA 1VG3A 1HXAA 3LG5A 5DJPF 5A0KA 2F8CF 2J5CA 5IKHA 3Q2QA 4RXCA 5CG5A 2I19A 3OACA 2F89F 1WKZA 3N5JF 5B01A 4NKEA 1EZFA 4FJQA 4K10A 4RYPA 5IL8A 4FP4A 1V4KA 3WEFA 5B0JA 2OA6A 4OMGA 3RYEA 3WCEA 1N1BA 3AQCB 2ONGA 3TFVA 3G4FA 1HXCA 3S4JA 1DGPA 3QKCA 1N23A 3NRIA 5B03A 4GP1A 3ICNA 5IMNA 4ZQ8A 3WJNA 5DW7A 1FPSA 2F7MF 3IPIA 4XQRF 3WSBA 4F6VA 1HX9A 1RQIA 4HD1A 1N22A 3KB9A 3WCAA 3V1XA 1HM7A 4KVIA 4DI5A 2Q58A 2ZCSA 4GP2A 4LA6A 3AE0A 4PVXF 2E4OA 5B02A 3LOMA 3WEIA 3TS7A 2FTZA 3M01A 3LSNA 5EASA 5DGSF 3WEJA 5ILDA 4RXEA 3KROB 4EA2A 1V4IA 2F8ZF 3N1VF 2AETA 4KWDA 1YQ7A 4N1ZF 3G4DA 3LJIA 5B0LA 2E92A 5DHIA 1VG6A 3KRCA 3ICZA 2H8OA 4H5EF 5DJVF 4KKMA 4KPJA 3DYGA 3N49F 3APZA 3WC9A 1ZW5A 3SAEA 2ZEUA 5B0IA 5EROA 1JFGA 3N45F 5C05A 1YV5A 3SDTA 5AHUB 3TC1A 3MZVA 3PYBA 1DI1A 3BNXA 1YYUA 3RYWA 1KIZA 3N3LF 5E8HA 4N9UA 4KQUA 3ZMCA 1V4HA 5DHKA 2Z4WA 4MC8A 3WCGA 4JYXA 4P0WA 3KRPB 5I1UA 1HM4A 5B00A 4E9UA 5DGMF 3WSAA 2O1OA 2E91A 2E8VA 5JV0F 4NFJF 3SDRA 3P8LA 3LEEA 3V1VA 3NPRA 4LA5A 4GA3A 1V4JA 4QXSF 1N1ZA 3Q2ZA 3LZ9A 3KRFB 5JV1F 3LK5A 3KRAA 2Q80A 4LTZA 5ILIA 2E95A 2AEKA 3PDEA 4JXYA 1V4EA 5DZ2A 3WCCA 4LPGF 3WE9A 3AQBB 4DEMF 3ID0A 5DGNF 3P41A 4RXAA 3ASXA 3OACB 3WCIA 1YYQA 2PS4A 5ERNA 3WCMA 4QPFA 1WL0A 3TFPA 4DZWA 4DXJA 4P0XA 2ZCOA 3N0GA 2ZCQA 5A0JA 2J1OA 5E8LA 3CC9A 3NF2A 4NKFA 2ZEVA 3PYAA 1UBYA 5H9DA 3LLWA 2Z7IA 3N6KF 2Z7HA 5AYPA 5IMPA 1WY0A 1YHMA 2AELA 3WCHA 4LZ0A 3P5RA 5HN7A 5DJRF 2E8WA 4OGUA 3EFQA 3TFNA 3VJBA 5AFXA 5AELA 2F92F 5HN8A 3ZMBA 4KQSA 4P0VA 3CKEA 5ILHA 3VJEA 3LDWA 3WJKA 4KK2A 1JFAA 4JXNA 4LIXA 5IVGA 5A0IA 4F6XA 5ILZA 3M00A 5IN8A 3KRCB 1HXGA 3N0FA 4L2XF 3VJCA 5ERMA 4NFKF 1RTRA 2PS8A 3PH7A 3DYHA 5JV2F 2AZJA
chains in the Genus database with same CATH superfamily
5ILYA 2FORA 2E93A 3B7LA 4OKZA 5ILJA 5DIQF 2EWGA 3LMDA 2Z4YA 2Z52A 3WCLA 3N3DA 3CP6A 3P5PA 4KVWA 4LFEA 2PS5A 3WJOA 3UCAA 2PS6A 1WL2A 4JVJF 4DWGA 5CG6A 3V66A 3ACWA 1N20A 4RNQA 3MAVA 3KBKA 2DH4A 5B0MA 4LXWA 5IL3A 1WL3A 2E90A 4LZCA 4DHDA 5ILKA 4MC0A 2F94F 1UBXA 4KFAA 1YHLA 3N46F 4LZ3A 3VJDA 4LUUA 3LGKA 3WCBA 5IMIA 5JA0F 3KRAB 2P1CA 2E8UA 5IK0A 1PS1A 3EZ3A 4OMHA 4XQSF 1UBVA 1YYRA 5EATA 3Q1OA 1UBWA 2VF6A 2Z4XA 3P8RA 3Q30A 3N1WF 1N24A 3QQVA 4KQ5A 3ICKA 3PKOA 4H5CF 4KPDA 2AZKA 4H5DF 4RXDA 1RQJA 3W7FA 3ACYA 2QISA 5JUZF 3ADZA 5IK9A 2ZCRA 2RAHA 3ICMA 4KVDA 4EA1A 4LFVF 4NUAA 5B0KA 5EAUA 1KIYA 4LFGA 3VJ9A 3IBAA 3OABA 3ZL6A 3RBMA 4DWBA 2Z4ZA 3ZOUA 1WL1A 3KROA 3LVSA 3ZCDA 5HNAA 3LGZB 3OABB 3WCFA 3NPKA 2E94A 2Q9ZA 5IM1A 2OPMA 2PS7A 2ZY1A 4WK5A 5IK6A 2OGDA 1N21A 4LPHF 3M02A 3RMGA 4XQTF 1YYTA 3AQ0A 3N5HF 2OPNA 4F62A 3SDVA 4Q23A 2Z78A 2E8XA 3SDQA 4JZBA 3WCDA 3SDUA 4OKMA 5E8KA 3WEHA 3M0GA 2E8TA 5IKAA 4E1EA 3M9UA 3DYFA 3OYRA 2AZLA 4LLSA 4E9ZA 4GAXA 3KRPA 1YJ4A 2J1PA 4LTVA 4PVYF 2ONHA 4EA0A 1VG4A 3BNYA 5ER8A 1VG2A 4UMJA 2Q9YA 5KSXF 2Z50A 3VJ8A 4KVYA 4LOBA 5HN9A 1VG7A 3WCJA 3ACXA 3S9VA 1YHKA 4MC3A 4JZXA 3EGTA 3WEGA 3VJAA 3KRFA 4LLTA 2Z4VA 4KUXA 4NFIF 1WMWA 3WEKA 2F9KF 4NG6A 1YYSA 1VG3A 1HXAA 3LG5A 5DJPF 5A0KA 2F8CF 2J5CA 5IKHA 3Q2QA 4RXCA 5CG5A 2I19A 3OACA 2F89F 1WKZA 3N5JF 5B01A 4NKEA 1EZFA 4FJQA 4K10A 4RYPA 5IL8A 4FP4A 1V4KA 3WEFA 5B0JA 2OA6A 4OMGA 3RYEA 3WCEA 1N1BA 3AQCB 2ONGA 3TFVA 3G4FA 1HXCA 3S4JA 1DGPA 3QKCA 1N23A 3NRIA 5B03A 4GP1A 3ICNA 5IMNA 4ZQ8A 3WJNA 5DW7A 1FPSA 2F7MF 3IPIA 4XQRF 3WSBA 4F6VA 1HX9A 1RQIA 4HD1A 1N22A 3KB9A 3WCAA 3V1XA 1HM7A 4KVIA 4DI5A 2Q58A 2ZCSA 4GP2A 4LA6A 3AE0A 4PVXF 2E4OA 5B02A 3LOMA 3WEIA 3TS7A 2FTZA 3M01A 3LSNA 5EASA 5DGSF 3WEJA 5ILDA 4RXEA 3KROB 4EA2A 1V4IA 2F8ZF 3N1VF 2AETA 4KWDA 1YQ7A 4N1ZF 3G4DA 3LJIA 5B0LA 2E92A 5DHIA 1VG6A 3KRCA 3ICZA 2H8OA 4H5EF 5DJVF 4KKMA 4KPJA 3DYGA 3N49F 3APZA 3WC9A 1ZW5A 3SAEA 2ZEUA 5B0IA 5EROA 1JFGA 3N45F 5C05A 1YV5A 3SDTA 5AHUB 3TC1A 3MZVA 3PYBA 1DI1A 3BNXA 1YYUA 3RYWA 1KIZA 3N3LF 5E8HA 4N9UA 4KQUA 3ZMCA 1V4HA 5DHKA 2Z4WA 4MC8A 3WCGA 4JYXA 4P0WA 3KRPB 5I1UA 1HM4A 5B00A 4E9UA 5DGMF 3WSAA 2O1OA 2E91A 2E8VA 5JV0F 4NFJF 3SDRA 3P8LA 3LEEA 3V1VA 3NPRA 4LA5A 4GA3A 1V4JA 4QXSF 1N1ZA 3Q2ZA 3LZ9A 3KRFB 5JV1F 3LK5A 3KRAA 2Q80A 4LTZA 5ILIA 2E95A 2AEKA 3PDEA 4JXYA 1V4EA 5DZ2A 3WCCA 4LPGF 3WE9A 3AQBB 4DEMF 3ID0A 5DGNF 3P41A 4RXAA 3ASXA 3OACB 3WCIA 1YYQA 2PS4A 5ERNA 3WCMA 4QPFA 1WL0A 3TFPA 4DZWA 4DXJA 4P0XA 2ZCOA 3N0GA 2ZCQA 5A0JA 2J1OA 5E8LA 3CC9A 3NF2A 4NKFA 2ZEVA 3PYAA 1UBYA 5H9DA 3LLWA 2Z7IA 3N6KF 2Z7HA 5AYPA 5IMPA 1WY0A 1YHMA 2AELA 3WCHA 4LZ0A 3P5RA 5HN7A 5DJRF 2E8WA 4OGUA 3EFQA 3TFNA 3VJBA 5AFXA 5AELA 2F92F 5HN8A 3ZMBA 4KQSA 4P0VA 3CKEA 5ILHA 3VJEA 3LDWA 3WJKA 4KK2A 1JFAA 4JXNA 4LIXA 5IVGA 5A0IA 4F6XA 5ILZA 3M00A 5IN8A 3KRCB 1HXGA 3N0FA 4L2XF 3VJCA 5ERMA 4NFKF 1RTRA 2PS8A 3PH7A 3DYHA 5JV2F 2AZJA
chains in the Genus database with same CATH topology
5ILYA 2FORA 2E93A 3B7LA 4OKZA 5ILJA 5DIQF 2EWGA 3LMDA 2Z4YA 2Z52A 3WCLA 3N3DA 3CP6A 3P5PA 4KVWA 4LFEA 2PS5A 3WJOA 3UCAA 2PS6A 1WL2A 4JVJF 4DWGA 5CG6A 3V66A 3ACWA 1N20A 4RNQA 3MAVA 3KBKA 2DH4A 5B0MA 4LXWA 5IL3A 1WL3A 2E90A 4LZCA 4DHDA 5ILKA 4MC0A 2F94F 1UBXA 4KFAA 1YHLA 3N46F 4LZ3A 3VJDA 4LUUA 3LGKA 3WCBA 5IMIA 5JA0F 3KRAB 2P1CA 2E8UA 5IK0A 1PS1A 3EZ3A 4OMHA 4XQSF 1UBVA 1YYRA 5EATA 3Q1OA 1UBWA 2VF6A 2Z4XA 3P8RA 3Q30A 3N1WF 1N24A 3QQVA 4KQ5A 3ICKA 3PKOA 4H5CF 4KPDA 2AZKA 4H5DF 4RXDA 1RQJA 3W7FA 3ACYA 2QISA 5JUZF 3ADZA 5IK9A 2ZCRA 2RAHA 3ICMA 4KVDA 4EA1A 4LFVF 4NUAA 5B0KA 5EAUA 1KIYA 4LFGA 3VJ9A 3IBAA 3OABA 3ZL6A 3RBMA 4DWBA 2Z4ZA 3ZOUA 1WL1A 3KROA 3LVSA 3ZCDA 5HNAA 3LGZB 3OABB 3WCFA 3NPKA 2E94A 2Q9ZA 5IM1A 2OPMA 2PS7A 2ZY1A 4WK5A 5IK6A 2OGDA 1N21A 4LPHF 3M02A 3RMGA 4XQTF 1YYTA 3AQ0A 3N5HF 2OPNA 4F62A 3SDVA 4Q23A 2Z78A 2E8XA 3SDQA 4JZBA 3WCDA 3SDUA 4OKMA 5E8KA 3WEHA 3M0GA 2E8TA 5IKAA 4E1EA 3M9UA 3DYFA 3OYRA 2AZLA 4LLSA 4E9ZA 4GAXA 3KRPA 1YJ4A 2J1PA 4LTVA 4PVYF 2ONHA 4EA0A 1VG4A 3BNYA 5ER8A 1VG2A 4UMJA 2Q9YA 5KSXF 2Z50A 3VJ8A 4KVYA 4LOBA 5HN9A 1VG7A 3WCJA 3ACXA 3S9VA 1YHKA 4MC3A 4JZXA 3EGTA 3WEGA 3VJAA 3KRFA 4LLTA 2Z4VA 4KUXA 4NFIF 1WMWA 3WEKA 2F9KF 4NG6A 1YYSA 1VG3A 1HXAA 3LG5A 5DJPF 5A0KA 2F8CF 2J5CA 5IKHA 3Q2QA 4RXCA 5CG5A 2I19A 3OACA 2F89F 1WKZA 3N5JF 5B01A 4NKEA 1EZFA 4FJQA 4K10A 4RYPA 5IL8A 4FP4A 1V4KA 3WEFA 5B0JA 2OA6A 4OMGA 3RYEA 3WCEA 1N1BA 3AQCB 2ONGA 3TFVA 3G4FA 1HXCA 3S4JA 1DGPA 3QKCA 1N23A 3NRIA 5B03A 4GP1A 3ICNA 5IMNA 4ZQ8A 3WJNA 5DW7A 1FPSA 2F7MF 3IPIA 4XQRF 3WSBA 4F6VA 1HX9A 1RQIA 4HD1A 1N22A 3KB9A 3WCAA 3V1XA 1HM7A 4KVIA 4DI5A 2Q58A 2ZCSA 4GP2A 4LA6A 3AE0A 4PVXF 2E4OA 5B02A 3LOMA 3WEIA 3TS7A 2FTZA 3M01A 3LSNA 5EASA 5DGSF 3WEJA 5ILDA 4RXEA 3KROB 4EA2A 1V4IA 2F8ZF 3N1VF 2AETA 4KWDA 1YQ7A 4N1ZF 3G4DA 3LJIA 5B0LA 2E92A 5DHIA 1VG6A 3KRCA 3ICZA 2H8OA 4H5EF 5DJVF 4KKMA 4KPJA 3DYGA 3N49F 3APZA 3WC9A 1ZW5A 3SAEA 2ZEUA 5B0IA 5EROA 1JFGA 3N45F 5C05A 1YV5A 3SDTA 5AHUB 3TC1A 3MZVA 3PYBA 1DI1A 3BNXA 1YYUA 3RYWA 1KIZA 3N3LF 5E8HA 4N9UA 4KQUA 3ZMCA 1V4HA 5DHKA 2Z4WA 4MC8A 3WCGA 4JYXA 4P0WA 3KRPB 5I1UA 1HM4A 5B00A 4E9UA 5DGMF 3WSAA 2O1OA 2E91A 2E8VA 5JV0F 4NFJF 3SDRA 3P8LA 3LEEA 3V1VA 3NPRA 4LA5A 4GA3A 1V4JA 4QXSF 1N1ZA 3Q2ZA 3LZ9A 3KRFB 5JV1F 3LK5A 3KRAA 2Q80A 4LTZA 5ILIA 2E95A 2AEKA 3PDEA 4JXYA 1V4EA 5DZ2A 3WCCA 4LPGF 3WE9A 3AQBB 4DEMF 3ID0A 5DGNF 3P41A 4RXAA 3ASXA 3OACB 3WCIA 1YYQA 2PS4A 5ERNA 3WCMA 4QPFA 1WL0A 3TFPA 4DZWA 4DXJA 4P0XA 2ZCOA 3N0GA 2ZCQA 5A0JA 2J1OA 5E8LA 3CC9A 3NF2A 4NKFA 2ZEVA 3PYAA 1UBYA 5H9DA 3LLWA 2Z7IA 3N6KF 2Z7HA 5AYPA 5IMPA 1WY0A 1YHMA 2AELA 3WCHA 4LZ0A 3P5RA 5HN7A 5DJRF 2E8WA 4OGUA 3EFQA 3TFNA 3VJBA 5AFXA 5AELA 2F92F 5HN8A 3ZMBA 4KQSA 4P0VA 3CKEA 5ILHA 3VJEA 3LDWA 3WJKA 4KK2A 1JFAA 4JXNA 4LIXA 5IVGA 5A0IA 4F6XA 5ILZA 3M00A 5IN8A 3KRCB 1HXGA 3N0FA 4L2XF 3VJCA 5ERMA 4NFKF 1RTRA 2PS8A 3PH7A 3DYHA 5JV2F 2AZJA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5ILY A;  2FOR A;  2E93 A;  3B7L A;  4OKZ A;  5ILJ A;  5DIQ F;  2EWG A;  3LMD A;  2Z4Y A;  2Z52 A;  3WCL A;  3N3D A;  3CP6 A;  3P5P A;  4KVW A;  4LFE A;  2PS5 A;  3WJO A;  3UCA A;  2PS6 A;  1WL2 A;  4JVJ F;  4DWG A;  5CG6 A;  3V66 A;  3ACW A;  1N20 A;  4RNQ A;  3MAV A;  3KBK A;  2DH4 A;  5B0M A;  4LXW A;  5IL3 A;  1WL3 A;  2E90 A;  4LZC A;  4DHD A;  5ILK A;  4MC0 A;  2F94 F;  1UBX A;  4KFA A;  1YHL A;  3N46 F;  4LZ3 A;  3VJD A;  4LUU A;  3LGK A;  3WCB A;  5IMI A;  5JA0 F;  3KRA B;  2P1C A;  2E8U A;  5IK0 A;  1PS1 A;  3EZ3 A;  4OMH A;  4XQS F;  1UBV A;  1YYR A;  5EAT A;  3Q1O A;  1UBW A;  2VF6 A;  2Z4X A;  3P8R A;  3Q30 A;  3N1W F;  1N24 A;  3QQV A;  4KQ5 A;  3ICK A;  3PKO A;  4H5C F;  4KPD A;  2AZK A;  4H5D F;  4RXD A;  1RQJ A;  3W7F A;  3ACY A;  2QIS A;  5JUZ F;  3ADZ A;  5IK9 A;  2ZCR A;  2RAH A;  3ICM A;  4KVD A;  4EA1 A;  4LFV F;  4NUA A;  5B0K A;  5EAU A;  1KIY A;  4LFG A;  3VJ9 A;  3IBA A;  3OAB A;  3ZL6 A;  3RBM A;  4DWB A;  2Z4Z A;  3ZOU A;  1WL1 A;  3KRO A;  3LVS A;  3ZCD A;  5HNA A;  3LGZ B;  3OAB B;  3WCF A;  3NPK A;  2E94 A;  2Q9Z A;  5IM1 A;  2OPM A;  2PS7 A;  2ZY1 A;  4WK5 A;  5IK6 A;  2OGD A;  1N21 A;  4LPH F;  3M02 A;  3RMG A;  4XQT F;  1YYT A;  3AQ0 A;  3N5H F;  2OPN A;  4F62 A;  3SDV A;  4Q23 A;  2Z78 A;  2E8X A;  3SDQ A;  4JZB A;  3WCD A;  3SDU A;  4OKM A;  5E8K A;  3WEH A;  3M0G A;  2E8T A;  5IKA A;  4E1E A;  3M9U A;  3DYF A;  3OYR A;  2AZL A;  4LLS A;  4E9Z A;  4GAX A;  3KRP A;  1YJ4 A;  2J1P A;  4LTV A;  4PVY F;  2ONH A;  4EA0 A;  1VG4 A;  3BNY A;  5ER8 A;  1VG2 A;  4UMJ A;  2Q9Y A;  5KSX F;  2Z50 A;  3VJ8 A;  4KVY A;  4LOB A;  5HN9 A;  1VG7 A;  3WCJ A;  3ACX A;  3S9V A;  1YHK A;  4MC3 A;  4JZX A;  3EGT A;  3WEG A;  3VJA A;  3KRF A;  4LLT A;  2Z4V A;  4KUX A;  4NFI F;  1WMW A;  3WEK A;  2F9K F;  4NG6 A;  1YYS A;  1VG3 A;  1HXA A;  3LG5 A;  5DJP F;  5A0K A;  2F8C F;  2J5C A;  5IKH A;  3Q2Q A;  4RXC A;  5CG5 A;  2I19 A;  3OAC A;  2F89 F;  1WKZ A;  3N5J F;  5B01 A;  4NKE A;  1EZF A;  4FJQ A;  4K10 A;  4RYP A;  5IL8 A;  4FP4 A;  1V4K A;  3WEF A;  5B0J A;  2OA6 A;  4OMG A;  3RYE A;  3WCE A;  1N1B A;  3AQC B;  2ONG A;  3TFV A;  3G4F A;  1HXC A;  3S4J A;  1DGP A;  3QKC A;  1N23 A;  3NRI A;  5B03 A;  4GP1 A;  3ICN A;  5IMN A;  4ZQ8 A;  3WJN A;  5DW7 A;  1FPS A;  2F7M F;  3IPI A;  4XQR F;  3WSB A;  4F6V A;  1HX9 A;  1RQI A;  4HD1 A;  1N22 A;  3KB9 A;  3WCA A;  3V1X A;  1HM7 A;  4KVI A;  4DI5 A;  2Q58 A;  2ZCS A;  4GP2 A;  4LA6 A;  3AE0 A;  4PVX F;  2E4O A;  5B02 A;  3LOM A;  3WEI A;  3TS7 A;  2FTZ A;  3M01 A;  3LSN A;  5EAS A;  5DGS F;  3WEJ A;  5ILD A;  4RXE A;  3KRO B;  4EA2 A;  1V4I A;  2F8Z F;  3N1V F;  2AET A;  4KWD A;  1YQ7 A;  4N1Z F;  3G4D A;  3LJI A;  5B0L A;  2E92 A;  5DHI A;  1VG6 A;  3KRC A;  3ICZ A;  2H8O A;  4H5E F;  5DJV F;  4KKM A;  4KPJ A;  3DYG A;  3N49 F;  3APZ A;  3WC9 A;  1ZW5 A;  3SAE A;  2ZEU A;  5B0I A;  5ERO A;  1JFG A;  3N45 F;  5C05 A;  1YV5 A;  3SDT A;  5AHU B;  3TC1 A;  3MZV A;  3PYB A;  1DI1 A;  3BNX A;  1YYU A;  3RYW A;  1KIZ A;  3N3L F;  5E8H A;  4N9U A;  4KQU A;  3ZMC A;  1V4H A;  5DHK A;  2Z4W A;  4MC8 A;  3WCG A;  4JYX A;  4P0W A;  3KRP B;  5I1U A;  1HM4 A;  5B00 A;  4E9U A;  5DGM F;  3WSA A;  2O1O A;  2E91 A;  2E8V A;  5JV0 F;  4NFJ F;  3SDR A;  3P8L A;  3LEE A;  3V1V A;  3NPR A;  4LA5 A;  4GA3 A;  1V4J A;  4QXS F;  1N1Z A;  3Q2Z A;  3LZ9 A;  3KRF B;  5JV1 F;  3LK5 A;  3KRA A;  2Q80 A;  4LTZ A;  5ILI A;  2E95 A;  2AEK A;  3PDE A;  4JXY A;  1V4E A;  5DZ2 A;  3WCC A;  4LPG F;  3WE9 A;  3AQB B;  4DEM F;  3ID0 A;  5DGN F;  3P41 A;  4RXA A;  3ASX A;  3OAC B;  3WCI A;  1YYQ A;  2PS4 A;  5ERN A;  3WCM A;  4QPF A;  1WL0 A;  3TFP A;  4DZW A;  4DXJ A;  4P0X A;  2ZCO A;  3N0G A;  2ZCQ A;  5A0J A;  2J1O A;  5E8L A;  3CC9 A;  3NF2 A;  4NKF A;  2ZEV A;  3PYA A;  1UBY A;  5H9D A;  3LLW A;  2Z7I A;  3N6K F;  2Z7H A;  5AYP A;  5IMP A;  1WY0 A;  1YHM A;  2AEL A;  3WCH A;  4LZ0 A;  3P5R A;  5HN7 A;  5DJR F;  2E8W A;  4OGU A;  3EFQ A;  3TFN A;  3VJB A;  5AFX A;  5AEL A;  2F92 F;  5HN8 A;  3ZMB A;  4KQS A;  4P0V A;  3CKE A;  5ILH A;  3VJE A;  3LDW A;  3WJK A;  4KK2 A;  1JFA A;  4JXN A;  4LIX A;  5IVG A;  5A0I A;  4F6X A;  5ILZ A;  3M00 A;  5IN8 A;  3KRC B;  1HXG A;  3N0F A;  4L2X F;  3VJC A;  5ERM A;  4NFK F;  1RTR A;  2PS8 A;  3PH7 A;  3DYH A;  5JV2 F;  2AZJ A; 
#chains in the Genus database with same CATH topology
 5ILY A;  2FOR A;  2E93 A;  3B7L A;  4OKZ A;  5ILJ A;  5DIQ F;  2EWG A;  3LMD A;  2Z4Y A;  2Z52 A;  3WCL A;  3N3D A;  3CP6 A;  3P5P A;  4KVW A;  4LFE A;  2PS5 A;  3WJO A;  3UCA A;  2PS6 A;  1WL2 A;  4JVJ F;  4DWG A;  5CG6 A;  3V66 A;  3ACW A;  1N20 A;  4RNQ A;  3MAV A;  3KBK A;  2DH4 A;  5B0M A;  4LXW A;  5IL3 A;  1WL3 A;  2E90 A;  4LZC A;  4DHD A;  5ILK A;  4MC0 A;  2F94 F;  1UBX A;  4KFA A;  1YHL A;  3N46 F;  4LZ3 A;  3VJD A;  4LUU A;  3LGK A;  3WCB A;  5IMI A;  5JA0 F;  3KRA B;  2P1C A;  2E8U A;  5IK0 A;  1PS1 A;  3EZ3 A;  4OMH A;  4XQS F;  1UBV A;  1YYR A;  5EAT A;  3Q1O A;  1UBW A;  2VF6 A;  2Z4X A;  3P8R A;  3Q30 A;  3N1W F;  1N24 A;  3QQV A;  4KQ5 A;  3ICK A;  3PKO A;  4H5C F;  4KPD A;  2AZK A;  4H5D F;  4RXD A;  1RQJ A;  3W7F A;  3ACY A;  2QIS A;  5JUZ F;  3ADZ A;  5IK9 A;  2ZCR A;  2RAH A;  3ICM A;  4KVD A;  4EA1 A;  4LFV F;  4NUA A;  5B0K A;  5EAU A;  1KIY A;  4LFG A;  3VJ9 A;  3IBA A;  3OAB A;  3ZL6 A;  3RBM A;  4DWB A;  2Z4Z A;  3ZOU A;  1WL1 A;  3KRO A;  3LVS A;  3ZCD A;  5HNA A;  3LGZ B;  3OAB B;  3WCF A;  3NPK A;  2E94 A;  2Q9Z A;  5IM1 A;  2OPM A;  2PS7 A;  2ZY1 A;  4WK5 A;  5IK6 A;  2OGD A;  1N21 A;  4LPH F;  3M02 A;  3RMG A;  4XQT F;  1YYT A;  3AQ0 A;  3N5H F;  2OPN A;  4F62 A;  3SDV A;  4Q23 A;  2Z78 A;  2E8X A;  3SDQ A;  4JZB A;  3WCD A;  3SDU A;  4OKM A;  5E8K A;  3WEH A;  3M0G A;  2E8T A;  5IKA A;  4E1E A;  3M9U A;  3DYF A;  3OYR A;  2AZL A;  4LLS A;  4E9Z A;  4GAX A;  3KRP A;  1YJ4 A;  2J1P A;  4LTV A;  4PVY F;  2ONH A;  4EA0 A;  1VG4 A;  3BNY A;  5ER8 A;  1VG2 A;  4UMJ A;  2Q9Y A;  5KSX F;  2Z50 A;  3VJ8 A;  4KVY A;  4LOB A;  5HN9 A;  1VG7 A;  3WCJ A;  3ACX A;  3S9V A;  1YHK A;  4MC3 A;  4JZX A;  3EGT A;  3WEG A;  3VJA A;  3KRF A;  4LLT A;  2Z4V A;  4KUX A;  4NFI F;  1WMW A;  3WEK A;  2F9K F;  4NG6 A;  1YYS A;  1VG3 A;  1HXA A;  3LG5 A;  5DJP F;  5A0K A;  2F8C F;  2J5C A;  5IKH A;  3Q2Q A;  4RXC A;  5CG5 A;  2I19 A;  3OAC A;  2F89 F;  1WKZ A;  3N5J F;  5B01 A;  4NKE A;  1EZF A;  4FJQ A;  4K10 A;  4RYP A;  5IL8 A;  4FP4 A;  1V4K A;  3WEF A;  5B0J A;  2OA6 A;  4OMG A;  3RYE A;  3WCE A;  1N1B A;  3AQC B;  2ONG A;  3TFV A;  3G4F A;  1HXC A;  3S4J A;  1DGP A;  3QKC A;  1N23 A;  3NRI A;  5B03 A;  4GP1 A;  3ICN A;  5IMN A;  4ZQ8 A;  3WJN A;  5DW7 A;  1FPS A;  2F7M F;  3IPI A;  4XQR F;  3WSB A;  4F6V A;  1HX9 A;  1RQI A;  4HD1 A;  1N22 A;  3KB9 A;  3WCA A;  3V1X A;  1HM7 A;  4KVI A;  4DI5 A;  2Q58 A;  2ZCS A;  4GP2 A;  4LA6 A;  3AE0 A;  4PVX F;  2E4O A;  5B02 A;  3LOM A;  3WEI A;  3TS7 A;  2FTZ A;  3M01 A;  3LSN A;  5EAS A;  5DGS F;  3WEJ A;  5ILD A;  4RXE A;  3KRO B;  4EA2 A;  1V4I A;  2F8Z F;  3N1V F;  2AET A;  4KWD A;  1YQ7 A;  4N1Z F;  3G4D A;  3LJI A;  5B0L A;  2E92 A;  5DHI A;  1VG6 A;  3KRC A;  3ICZ A;  2H8O A;  4H5E F;  5DJV F;  4KKM A;  4KPJ A;  3DYG A;  3N49 F;  3APZ A;  3WC9 A;  1ZW5 A;  3SAE A;  2ZEU A;  5B0I A;  5ERO A;  1JFG A;  3N45 F;  5C05 A;  1YV5 A;  3SDT A;  5AHU B;  3TC1 A;  3MZV A;  3PYB A;  1DI1 A;  3BNX A;  1YYU A;  3RYW A;  1KIZ A;  3N3L F;  5E8H A;  4N9U A;  4KQU A;  3ZMC A;  1V4H A;  5DHK A;  2Z4W A;  4MC8 A;  3WCG A;  4JYX A;  4P0W A;  3KRP B;  5I1U A;  1HM4 A;  5B00 A;  4E9U A;  5DGM F;  3WSA A;  2O1O A;  2E91 A;  2E8V A;  5JV0 F;  4NFJ F;  3SDR A;  3P8L A;  3LEE A;  3V1V A;  3NPR A;  4LA5 A;  4GA3 A;  1V4J A;  4QXS F;  1N1Z A;  3Q2Z A;  3LZ9 A;  3KRF B;  5JV1 F;  3LK5 A;  3KRA A;  2Q80 A;  4LTZ A;  5ILI A;  2E95 A;  2AEK A;  3PDE A;  4JXY A;  1V4E A;  5DZ2 A;  3WCC A;  4LPG F;  3WE9 A;  3AQB B;  4DEM F;  3ID0 A;  5DGN F;  3P41 A;  4RXA A;  3ASX A;  3OAC B;  3WCI A;  1YYQ A;  2PS4 A;  5ERN A;  3WCM A;  4QPF A;  1WL0 A;  3TFP A;  4DZW A;  4DXJ A;  4P0X A;  2ZCO A;  3N0G A;  2ZCQ A;  5A0J A;  2J1O A;  5E8L A;  3CC9 A;  3NF2 A;  4NKF A;  2ZEV A;  3PYA A;  1UBY A;  5H9D A;  3LLW A;  2Z7I A;  3N6K F;  2Z7H A;  5AYP A;  5IMP A;  1WY0 A;  1YHM A;  2AEL A;  3WCH A;  4LZ0 A;  3P5R A;  5HN7 A;  5DJR F;  2E8W A;  4OGU A;  3EFQ A;  3TFN A;  3VJB A;  5AFX A;  5AEL A;  2F92 F;  5HN8 A;  3ZMB A;  4KQS A;  4P0V A;  3CKE A;  5ILH A;  3VJE A;  3LDW A;  3WJK A;  4KK2 A;  1JFA A;  4JXN A;  4LIX A;  5IVG A;  5A0I A;  4F6X A;  5ILZ A;  3M00 A;  5IN8 A;  3KRC B;  1HXG A;  3N0F A;  4L2X F;  3VJC A;  5ERM A;  4NFK F;  1RTR A;  2PS8 A;  3PH7 A;  3DYH A;  5JV2 F;  2AZJ A; 
#chains in the Genus database with same CATH homology
 5ILY A;  2FOR A;  2E93 A;  3B7L A;  4OKZ A;  5ILJ A;  5DIQ F;  2EWG A;  3LMD A;  2Z4Y A;  2Z52 A;  3WCL A;  3N3D A;  3CP6 A;  3P5P A;  4KVW A;  4LFE A;  2PS5 A;  3WJO A;  3UCA A;  2PS6 A;  1WL2 A;  4JVJ F;  4DWG A;  5CG6 A;  3V66 A;  3ACW A;  1N20 A;  4RNQ A;  3MAV A;  3KBK A;  2DH4 A;  5B0M A;  4LXW A;  5IL3 A;  1WL3 A;  2E90 A;  4LZC A;  4DHD A;  5ILK A;  4MC0 A;  2F94 F;  1UBX A;  4KFA A;  1YHL A;  3N46 F;  4LZ3 A;  3VJD A;  4LUU A;  3LGK A;  3WCB A;  5IMI A;  5JA0 F;  3KRA B;  2P1C A;  2E8U A;  5IK0 A;  1PS1 A;  3EZ3 A;  4OMH A;  4XQS F;  1UBV A;  1YYR A;  5EAT A;  3Q1O A;  1UBW A;  2VF6 A;  2Z4X A;  3P8R A;  3Q30 A;  3N1W F;  1N24 A;  3QQV A;  4KQ5 A;  3ICK A;  3PKO A;  4H5C F;  4KPD A;  2AZK A;  4H5D F;  4RXD A;  1RQJ A;  3W7F A;  3ACY A;  2QIS A;  5JUZ F;  3ADZ A;  5IK9 A;  2ZCR A;  2RAH A;  3ICM A;  4KVD A;  4EA1 A;  4LFV F;  4NUA A;  5B0K A;  5EAU A;  1KIY A;  4LFG A;  3VJ9 A;  3IBA A;  3OAB A;  3ZL6 A;  3RBM A;  4DWB A;  2Z4Z A;  3ZOU A;  1WL1 A;  3KRO A;  3LVS A;  3ZCD A;  5HNA A;  3LGZ B;  3OAB B;  3WCF A;  3NPK A;  2E94 A;  2Q9Z A;  5IM1 A;  2OPM A;  2PS7 A;  2ZY1 A;  4WK5 A;  5IK6 A;  2OGD A;  1N21 A;  4LPH F;  3M02 A;  3RMG A;  4XQT F;  1YYT A;  3AQ0 A;  3N5H F;  2OPN A;  4F62 A;  3SDV A;  4Q23 A;  2Z78 A;  2E8X A;  3SDQ A;  4JZB A;  3WCD A;  3SDU A;  4OKM A;  5E8K A;  3WEH A;  3M0G A;  2E8T A;  5IKA A;  4E1E A;  3M9U A;  3DYF A;  3OYR A;  2AZL A;  4LLS A;  4E9Z A;  4GAX A;  3KRP A;  1YJ4 A;  2J1P A;  4LTV A;  4PVY F;  2ONH A;  4EA0 A;  1VG4 A;  3BNY A;  5ER8 A;  1VG2 A;  4UMJ A;  2Q9Y A;  5KSX F;  2Z50 A;  3VJ8 A;  4KVY A;  4LOB A;  5HN9 A;  1VG7 A;  3WCJ A;  3ACX A;  3S9V A;  1YHK A;  4MC3 A;  4JZX A;  3EGT A;  3WEG A;  3VJA A;  3KRF A;  4LLT A;  2Z4V A;  4KUX A;  4NFI F;  1WMW A;  3WEK A;  2F9K F;  4NG6 A;  1YYS A;  1VG3 A;  1HXA A;  3LG5 A;  5DJP F;  5A0K A;  2F8C F;  2J5C A;  5IKH A;  3Q2Q A;  4RXC A;  5CG5 A;  2I19 A;  3OAC A;  2F89 F;  1WKZ A;  3N5J F;  5B01 A;  4NKE A;  1EZF A;  4FJQ A;  4K10 A;  4RYP A;  5IL8 A;  4FP4 A;  1V4K A;  3WEF A;  5B0J A;  2OA6 A;  4OMG A;  3RYE A;  3WCE A;  1N1B A;  3AQC B;  2ONG A;  3TFV A;  3G4F A;  1HXC A;  3S4J A;  1DGP A;  3QKC A;  1N23 A;  3NRI A;  5B03 A;  4GP1 A;  3ICN A;  5IMN A;  4ZQ8 A;  3WJN A;  5DW7 A;  1FPS A;  2F7M F;  3IPI A;  4XQR F;  3WSB A;  4F6V A;  1HX9 A;  1RQI A;  4HD1 A;  1N22 A;  3KB9 A;  3WCA A;  3V1X A;  1HM7 A;  4KVI A;  4DI5 A;  2Q58 A;  2ZCS A;  4GP2 A;  4LA6 A;  3AE0 A;  4PVX F;  2E4O A;  5B02 A;  3LOM A;  3WEI A;  3TS7 A;  2FTZ A;  3M01 A;  3LSN A;  5EAS A;  5DGS F;  3WEJ A;  5ILD A;  4RXE A;  3KRO B;  4EA2 A;  1V4I A;  2F8Z F;  3N1V F;  2AET A;  4KWD A;  1YQ7 A;  4N1Z F;  3G4D A;  3LJI A;  5B0L A;  2E92 A;  5DHI A;  1VG6 A;  3KRC A;  3ICZ A;  2H8O A;  4H5E F;  5DJV F;  4KKM A;  4KPJ A;  3DYG A;  3N49 F;  3APZ A;  3WC9 A;  1ZW5 A;  3SAE A;  2ZEU A;  5B0I A;  5ERO A;  1JFG A;  3N45 F;  5C05 A;  1YV5 A;  3SDT A;  5AHU B;  3TC1 A;  3MZV A;  3PYB A;  1DI1 A;  3BNX A;  1YYU A;  3RYW A;  1KIZ A;  3N3L F;  5E8H A;  4N9U A;  4KQU A;  3ZMC A;  1V4H A;  5DHK A;  2Z4W A;  4MC8 A;  3WCG A;  4JYX A;  4P0W A;  3KRP B;  5I1U A;  1HM4 A;  5B00 A;  4E9U A;  5DGM F;  3WSA A;  2O1O A;  2E91 A;  2E8V A;  5JV0 F;  4NFJ F;  3SDR A;  3P8L A;  3LEE A;  3V1V A;  3NPR A;  4LA5 A;  4GA3 A;  1V4J A;  4QXS F;  1N1Z A;  3Q2Z A;  3LZ9 A;  3KRF B;  5JV1 F;  3LK5 A;  3KRA A;  2Q80 A;  4LTZ A;  5ILI A;  2E95 A;  2AEK A;  3PDE A;  4JXY A;  1V4E A;  5DZ2 A;  3WCC A;  4LPG F;  3WE9 A;  3AQB B;  4DEM F;  3ID0 A;  5DGN F;  3P41 A;  4RXA A;  3ASX A;  3OAC B;  3WCI A;  1YYQ A;  2PS4 A;  5ERN A;  3WCM A;  4QPF A;  1WL0 A;  3TFP A;  4DZW A;  4DXJ A;  4P0X A;  2ZCO A;  3N0G A;  2ZCQ A;  5A0J A;  2J1O A;  5E8L A;  3CC9 A;  3NF2 A;  4NKF A;  2ZEV A;  3PYA A;  1UBY A;  5H9D A;  3LLW A;  2Z7I A;  3N6K F;  2Z7H A;  5AYP A;  5IMP A;  1WY0 A;  1YHM A;  2AEL A;  3WCH A;  4LZ0 A;  3P5R A;  5HN7 A;  5DJR F;  2E8W A;  4OGU A;  3EFQ A;  3TFN A;  3VJB A;  5AFX A;  5AEL A;  2F92 F;  5HN8 A;  3ZMB A;  4KQS A;  4P0V A;  3CKE A;  5ILH A;  3VJE A;  3LDW A;  3WJK A;  4KK2 A;  1JFA A;  4JXN A;  4LIX A;  5IVG A;  5A0I A;  4F6X A;  5ILZ A;  3M00 A;  5IN8 A;  3KRC B;  1HXG A;  3N0F A;  4L2X F;  3VJC A;  5ERM A;  4NFK F;  1RTR A;  2PS8 A;  3PH7 A;  3DYH A;  5JV2 F;  2AZJ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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