3WEIA

Crystal structure of the human squalene synthase y73a mutant in complex with presqualene pyrophosphate
Total Genus 140
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
140
sequence length
334
structure length
334
Chain Sequence
LSSSLKTCYKYLNQTSRSFAAVIQALDGEMRNAVCIFALVLRALDTLEDDMTISVEKKVPLLHNFHSFLYQPDWRFMESKEKDRQVLEDFPTISLEFRNLAEKYQTVIADICRRMGIGMAEFLDKHVTSEQEWDKYCHYVAGLVGIGLSRLFSASEFEDPLVGEDTERANSMGLFLQKTNIIRDYLEDQQGGREFWPQEVWSRYVKKLGDFAKPENIDLAVQCLNELITNALHHIPDVITYLSRLRNQSVFNFCAIPQVMAIATLAACYNNQQVFKGAVKIRKGQAVTLMMDATNMPAVKAIIYQYMEEIYHRIPDSDPSSSKTRQIISTIRTQ
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural insights into the catalytic mechanism of human squalene synthase
doi rcsb
molecule tags Transferase
source organism Homo sapiens
molecule keywords Squalene synthase
total genus 140
structure length 334
sequence length 334
ec nomenclature ec 2.5.1.21: Squalene synthase.
pdb deposition date 2013-07-07

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00494 SQS_PSY Squalene/phytoene synthase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.600.10 Mainly Alpha Orthogonal Bundle Farnesyl Diphosphate Synthase Farnesyl Diphosphate Synthase 3weiA00
3ICZA 3KRPB 4NG6A 3N3DA 1WL3A 1VG4A 3B7LA 2E8XA 4EA0A 4KVWA 3ZMBA 3ZOUA 5JUZF 2FTZA 5B00A 4LFGA 4RXEA 4P0XA 2F9KF 4HD1A 2Q9ZA 4F6XA 4L2XF 5DHKA 4LUUA 4QPFA 3QQVA 3VJAA 3WEJA 1UBXA 1WL2A 3DYHA 3WCHA 5IM1A 3WSBA 5B02A 5B01A 2Z78A 3Q1OA 4KQSA 3AQ0A 3WCBA 4JXYA 5AFXA 1VG2A 2J1OA 1V4IA 3CKEA 3V1VA 1YYUA 2RAHA 5ERNA 4JZXA 3KBKA 3LVSA 2Z4ZA 4DHDA 3ICKA 3WSAA 2FORA 3KRCA 4KWDA 4LLTA 3IBAA 2E93A 3VJDA 4NFIF 3VJBA 3OABB 2ZCOA 5IKHA 2J5CA 3VJEA 2F89F 2AZKA 5DJRF 3WCIA 5EAUA 5JV0F 1V4EA 3NPRA 3DYGA 4OKZA 5IK6A 4LZCA 3LMDA 3KRAA 2PS6A 5HN7A 3RMGA 1YV5A 4LZ0A 5IL3A 4LOBA 3LDWA 4KVYA 1N21A 2DH4A 1N1ZA 4EA1A 4MC3A 2H8OA 3ICNA 4LPGF 3WCJA 2OPMA 2Z52A 3WJNA 5A0IA 2E91A 2QISA 2ZCSA 4H5DF 3KRAB 3LJIA 2Z7IA 1V4HA 4E9ZA 1YYTA 3CC9A 3AQBB 1JFAA 4MC0A 4RXDA 5B0KA 5DW7A 4LPHF 1WKZA 4XQRF 4LA6A 1UBWA 4KQ5A 5DGNF 4FJQA 2Z50A 5B03A 2E8UA 3LGZB 4JYXA 5CG5A 5B0MA 3RBMA 5DIQF 4KUXA 3VJCA 2OPNA 1YYSA 5DZ2A 3P5RA 4OMHA 3LSNA 3ADZA 4H5CF 4XQTF 3KRFA 4GP2A 3ZMCA 3N0GA 4EA2A 2ONGA 1RQIA 2F8ZF 3WCLA 5IMIA 2PS7A 1KIYA 4OMGA 4E9UA 2ZEUA 3M9UA 1VG6A 5A0KA 4GP1A 5JV1F 2P1CA 4DWBA 4DWGA 2O1OA 3WCGA 3VJ9A 3ACWA 2ZEVA 3MAVA 2PS5A 2I19A 4LIXA 2F94F 3QKCA 4LZ3A 3M0GA 2AZLA 4RYPA 3WEHA 3AE0A 3EGTA 1YHLA 2PS4A 4KFAA 1UBYA 2F92F 3Q2ZA 5IMNA 4LA5A 4LFVF 5IL8A 4GAXA 5DJPF 5CG6A 3TFVA 3AQCB 3N49F 3P5PA 3W7FA 3N46F 3P8LA 5AHUB 1HX9A 3PKOA 3KROA 3Q30A 3M02A 1YHKA 4FP4A 3S4JA 4DI5A 4KPJA 5A0JA 3LEEA 4P0WA 3WCCA 2AZJA 4QXSF 3SDQA 4N9UA 1HM7A 2Z4XA 3PYAA 4N1ZF 1KIZA 4NUAA 1N20A 3S9VA 5E8HA 3WCDA 1DI1A 3KROB 3NPKA 3VJ8A 5ER8A 5B0JA 2E95A 3KRCB 3EFQA 2AETA 3LLWA 5HN9A 5ILZA 3M00A 4Q23A 3N5HF 5E8LA 1WL0A 3N45F 3LG5A 3G4DA 5AELA 4KPDA 1VG3A 3WCEA 3PH7A 1V4JA 3NF2A 5EROA 3WCFA 2F8CF 3TFNA 4OKMA 4KVDA 1HXGA 4GA3A 4KVIA 3WCAA 3NRIA 5KSXF 5ILJA 1WMWA 3N0FA 3LGKA 5ILYA 5EASA 4DZWA 2E8VA 3OACA 2VF6A 5H9DA 5ERMA 1YHMA 3ZCDA 1JFGA 4F62A 4DXJA 4K10A 4LXWA 2E4OA 3ZL6A 3KRPA 3P8RA 4LTVA 1N22A 2E94A 4NKEA 5HN8A 1N23A 1DGPA 3WJKA 3WEKA 4UMJA 5ILIA 1YYRA 5B0IA 2AELA 2OGDA 2ZCRA 1V4KA 3KRFB 3WEGA 3WE9A 5IK9A 3APZA 4F6VA 4RXCA 2E90A 1HXCA 1YQ7A 2Q9YA 5I1UA 4NKFA 3SDUA 2E8WA 3SDVA 4PVXF 4RXAA 3Q2QA 1EZFA 3SDTA 3TFPA 4JZBA 2PS8A 3WCMA 4XQSF 3LOMA 1N24A 3N5JF 2EWGA 3CP6A 2ZY1A 3OYRA 4NFKF 2F7MF 2ONHA 4ZQ8A 3EZ3A 4KQUA 3UCAA 5EATA 3RYEA 3OABA 1VG7A 2AEKA 4LLSA 2Z7HA 3WEIA 3N3LF 3N6KF 3LK5A 4KKMA 1RQJA 3ID0A 3ACYA 1FPSA 2Q80A 1WL1A 2Z4VA 3BNXA 5IN8A 5ILDA 3M01A 5JA0F 1PS1A 4RNQA 1N1BA 5DGSF 3ICMA 4H5EF 4LTZA 5AYPA 4JXNA 4KK2A 3V1XA 3DYFA 3IPIA 3N1VF 5ILHA 3WJOA 2OA6A 2E8TA 3V66A 1HXAA 3WEFA 4LFEA 3LZ9A 5JV2F 5B0LA 2ZCQA 4P0VA 4NFJF 3KB9A 4WK5A 3SAEA 4PVYF 2E92A 3WC9A 3N1WF 3ACXA 3PYBA 3G4FA 4JVJF 1YYQA 5DJVF 3ASXA 5IVGA 4E1EA 5ILKA 5C05A 4OGUA 3SDRA 5E8KA 5DHIA 3OACB 1RTRA 5IKAA 2Z4YA 2Z4WA 1YJ4A 5IK0A 1WY0A 2Q58A 3BNYA 5DGMF 3PDEA 4MC8A 5IMPA 1UBVA 3MZVA 1HM4A 3TS7A 4DEMF 5HNAA 1ZW5A 3P41A 3TC1A 3RYWA 2J1PA
chains in the Genus database with same CATH superfamily
3ICZA 3KRPB 4NG6A 3N3DA 1WL3A 1VG4A 3B7LA 2E8XA 4EA0A 4KVWA 3ZMBA 3ZOUA 5JUZF 2FTZA 5B00A 4LFGA 4RXEA 4P0XA 2F9KF 4HD1A 2Q9ZA 4F6XA 4L2XF 5DHKA 4LUUA 4QPFA 3QQVA 3VJAA 3WEJA 1UBXA 1WL2A 3DYHA 3WCHA 5IM1A 3WSBA 5B02A 5B01A 2Z78A 3Q1OA 4KQSA 3AQ0A 3WCBA 4JXYA 5AFXA 1VG2A 2J1OA 1V4IA 3CKEA 3V1VA 1YYUA 2RAHA 5ERNA 4JZXA 3KBKA 3LVSA 2Z4ZA 4DHDA 3ICKA 3WSAA 2FORA 3KRCA 4KWDA 4LLTA 3IBAA 2E93A 3VJDA 4NFIF 3VJBA 3OABB 2ZCOA 5IKHA 2J5CA 3VJEA 2F89F 2AZKA 5DJRF 3WCIA 5EAUA 5JV0F 1V4EA 3NPRA 3DYGA 4OKZA 5IK6A 4LZCA 3LMDA 3KRAA 2PS6A 5HN7A 3RMGA 1YV5A 4LZ0A 5IL3A 4LOBA 3LDWA 4KVYA 1N21A 2DH4A 1N1ZA 4EA1A 4MC3A 2H8OA 3ICNA 4LPGF 3WCJA 2OPMA 2Z52A 3WJNA 5A0IA 2E91A 2QISA 2ZCSA 4H5DF 3KRAB 3LJIA 2Z7IA 1V4HA 4E9ZA 1YYTA 3CC9A 3AQBB 1JFAA 4MC0A 4RXDA 5B0KA 5DW7A 4LPHF 1WKZA 4XQRF 4LA6A 1UBWA 4KQ5A 5DGNF 4FJQA 2Z50A 5B03A 2E8UA 3LGZB 4JYXA 5CG5A 5B0MA 3RBMA 5DIQF 4KUXA 3VJCA 2OPNA 1YYSA 5DZ2A 3P5RA 4OMHA 3LSNA 3ADZA 4H5CF 4XQTF 3KRFA 4GP2A 3ZMCA 3N0GA 4EA2A 2ONGA 1RQIA 2F8ZF 3WCLA 5IMIA 2PS7A 1KIYA 4OMGA 4E9UA 2ZEUA 3M9UA 1VG6A 5A0KA 4GP1A 5JV1F 2P1CA 4DWBA 4DWGA 2O1OA 3WCGA 3VJ9A 3ACWA 2ZEVA 3MAVA 2PS5A 2I19A 4LIXA 2F94F 3QKCA 4LZ3A 3M0GA 2AZLA 4RYPA 3WEHA 3AE0A 3EGTA 1YHLA 2PS4A 4KFAA 1UBYA 2F92F 3Q2ZA 5IMNA 4LA5A 4LFVF 5IL8A 4GAXA 5DJPF 5CG6A 3TFVA 3AQCB 3N49F 3P5PA 3W7FA 3N46F 3P8LA 5AHUB 1HX9A 3PKOA 3KROA 3Q30A 3M02A 1YHKA 4FP4A 3S4JA 4DI5A 4KPJA 5A0JA 3LEEA 4P0WA 3WCCA 2AZJA 4QXSF 3SDQA 4N9UA 1HM7A 2Z4XA 3PYAA 4N1ZF 1KIZA 4NUAA 1N20A 3S9VA 5E8HA 3WCDA 1DI1A 3KROB 3NPKA 3VJ8A 5ER8A 5B0JA 2E95A 3KRCB 3EFQA 2AETA 3LLWA 5HN9A 5ILZA 3M00A 4Q23A 3N5HF 5E8LA 1WL0A 3N45F 3LG5A 3G4DA 5AELA 4KPDA 1VG3A 3WCEA 3PH7A 1V4JA 3NF2A 5EROA 3WCFA 2F8CF 3TFNA 4OKMA 4KVDA 1HXGA 4GA3A 4KVIA 3WCAA 3NRIA 5KSXF 5ILJA 1WMWA 3N0FA 3LGKA 5ILYA 5EASA 4DZWA 2E8VA 3OACA 2VF6A 5H9DA 5ERMA 1YHMA 3ZCDA 1JFGA 4F62A 4DXJA 4K10A 4LXWA 2E4OA 3ZL6A 3KRPA 3P8RA 4LTVA 1N22A 2E94A 4NKEA 5HN8A 1N23A 1DGPA 3WJKA 3WEKA 4UMJA 5ILIA 1YYRA 5B0IA 2AELA 2OGDA 2ZCRA 1V4KA 3KRFB 3WEGA 3WE9A 5IK9A 3APZA 4F6VA 4RXCA 2E90A 1HXCA 1YQ7A 2Q9YA 5I1UA 4NKFA 3SDUA 2E8WA 3SDVA 4PVXF 4RXAA 3Q2QA 1EZFA 3SDTA 3TFPA 4JZBA 2PS8A 3WCMA 4XQSF 3LOMA 1N24A 3N5JF 2EWGA 3CP6A 2ZY1A 3OYRA 4NFKF 2F7MF 2ONHA 4ZQ8A 3EZ3A 4KQUA 3UCAA 5EATA 3RYEA 3OABA 1VG7A 2AEKA 4LLSA 2Z7HA 3WEIA 3N3LF 3N6KF 3LK5A 4KKMA 1RQJA 3ID0A 3ACYA 1FPSA 2Q80A 1WL1A 2Z4VA 3BNXA 5IN8A 5ILDA 3M01A 5JA0F 1PS1A 4RNQA 1N1BA 5DGSF 3ICMA 4H5EF 4LTZA 5AYPA 4JXNA 4KK2A 3V1XA 3DYFA 3IPIA 3N1VF 5ILHA 3WJOA 2OA6A 2E8TA 3V66A 1HXAA 3WEFA 4LFEA 3LZ9A 5JV2F 5B0LA 2ZCQA 4P0VA 4NFJF 3KB9A 4WK5A 3SAEA 4PVYF 2E92A 3WC9A 3N1WF 3ACXA 3PYBA 3G4FA 4JVJF 1YYQA 5DJVF 3ASXA 5IVGA 4E1EA 5ILKA 5C05A 4OGUA 3SDRA 5E8KA 5DHIA 3OACB 1RTRA 5IKAA 2Z4YA 2Z4WA 1YJ4A 5IK0A 1WY0A 2Q58A 3BNYA 5DGMF 3PDEA 4MC8A 5IMPA 1UBVA 3MZVA 1HM4A 3TS7A 4DEMF 5HNAA 1ZW5A 3P41A 3TC1A 3RYWA 2J1PA
chains in the Genus database with same CATH topology
3ICZA 3KRPB 4NG6A 3N3DA 1WL3A 1VG4A 3B7LA 2E8XA 4EA0A 4KVWA 3ZMBA 3ZOUA 5JUZF 2FTZA 5B00A 4LFGA 4RXEA 4P0XA 2F9KF 4HD1A 2Q9ZA 4F6XA 4L2XF 5DHKA 4LUUA 4QPFA 3QQVA 3VJAA 3WEJA 1UBXA 1WL2A 3DYHA 3WCHA 5IM1A 3WSBA 5B02A 5B01A 2Z78A 3Q1OA 4KQSA 3AQ0A 3WCBA 4JXYA 5AFXA 1VG2A 2J1OA 1V4IA 3CKEA 3V1VA 1YYUA 2RAHA 5ERNA 4JZXA 3KBKA 3LVSA 2Z4ZA 4DHDA 3ICKA 3WSAA 2FORA 3KRCA 4KWDA 4LLTA 3IBAA 2E93A 3VJDA 4NFIF 3VJBA 3OABB 2ZCOA 5IKHA 2J5CA 3VJEA 2F89F 2AZKA 5DJRF 3WCIA 5EAUA 5JV0F 1V4EA 3NPRA 3DYGA 4OKZA 5IK6A 4LZCA 3LMDA 3KRAA 2PS6A 5HN7A 3RMGA 1YV5A 4LZ0A 5IL3A 4LOBA 3LDWA 4KVYA 1N21A 2DH4A 1N1ZA 4EA1A 4MC3A 2H8OA 3ICNA 4LPGF 3WCJA 2OPMA 2Z52A 3WJNA 5A0IA 2E91A 2QISA 2ZCSA 4H5DF 3KRAB 3LJIA 2Z7IA 1V4HA 4E9ZA 1YYTA 3CC9A 3AQBB 1JFAA 4MC0A 4RXDA 5B0KA 5DW7A 4LPHF 1WKZA 4XQRF 4LA6A 1UBWA 4KQ5A 5DGNF 4FJQA 2Z50A 5B03A 2E8UA 3LGZB 4JYXA 5CG5A 5B0MA 3RBMA 5DIQF 4KUXA 3VJCA 2OPNA 1YYSA 5DZ2A 3P5RA 4OMHA 3LSNA 3ADZA 4H5CF 4XQTF 3KRFA 4GP2A 3ZMCA 3N0GA 4EA2A 2ONGA 1RQIA 2F8ZF 3WCLA 5IMIA 2PS7A 1KIYA 4OMGA 4E9UA 2ZEUA 3M9UA 1VG6A 5A0KA 4GP1A 5JV1F 2P1CA 4DWBA 4DWGA 2O1OA 3WCGA 3VJ9A 3ACWA 2ZEVA 3MAVA 2PS5A 2I19A 4LIXA 2F94F 3QKCA 4LZ3A 3M0GA 2AZLA 4RYPA 3WEHA 3AE0A 3EGTA 1YHLA 2PS4A 4KFAA 1UBYA 2F92F 3Q2ZA 5IMNA 4LA5A 4LFVF 5IL8A 4GAXA 5DJPF 5CG6A 3TFVA 3AQCB 3N49F 3P5PA 3W7FA 3N46F 3P8LA 5AHUB 1HX9A 3PKOA 3KROA 3Q30A 3M02A 1YHKA 4FP4A 3S4JA 4DI5A 4KPJA 5A0JA 3LEEA 4P0WA 3WCCA 2AZJA 4QXSF 3SDQA 4N9UA 1HM7A 2Z4XA 3PYAA 4N1ZF 1KIZA 4NUAA 1N20A 3S9VA 5E8HA 3WCDA 1DI1A 3KROB 3NPKA 3VJ8A 5ER8A 5B0JA 2E95A 3KRCB 3EFQA 2AETA 3LLWA 5HN9A 5ILZA 3M00A 4Q23A 3N5HF 5E8LA 1WL0A 3N45F 3LG5A 3G4DA 5AELA 4KPDA 1VG3A 3WCEA 3PH7A 1V4JA 3NF2A 5EROA 3WCFA 2F8CF 3TFNA 4OKMA 4KVDA 1HXGA 4GA3A 4KVIA 3WCAA 3NRIA 5KSXF 5ILJA 1WMWA 3N0FA 3LGKA 5ILYA 5EASA 4DZWA 2E8VA 3OACA 2VF6A 5H9DA 5ERMA 1YHMA 3ZCDA 1JFGA 4F62A 4DXJA 4K10A 4LXWA 2E4OA 3ZL6A 3KRPA 3P8RA 4LTVA 1N22A 2E94A 4NKEA 5HN8A 1N23A 1DGPA 3WJKA 3WEKA 4UMJA 5ILIA 1YYRA 5B0IA 2AELA 2OGDA 2ZCRA 1V4KA 3KRFB 3WEGA 3WE9A 5IK9A 3APZA 4F6VA 4RXCA 2E90A 1HXCA 1YQ7A 2Q9YA 5I1UA 4NKFA 3SDUA 2E8WA 3SDVA 4PVXF 4RXAA 3Q2QA 1EZFA 3SDTA 3TFPA 4JZBA 2PS8A 3WCMA 4XQSF 3LOMA 1N24A 3N5JF 2EWGA 3CP6A 2ZY1A 3OYRA 4NFKF 2F7MF 2ONHA 4ZQ8A 3EZ3A 4KQUA 3UCAA 5EATA 3RYEA 3OABA 1VG7A 2AEKA 4LLSA 2Z7HA 3WEIA 3N3LF 3N6KF 3LK5A 4KKMA 1RQJA 3ID0A 3ACYA 1FPSA 2Q80A 1WL1A 2Z4VA 3BNXA 5IN8A 5ILDA 3M01A 5JA0F 1PS1A 4RNQA 1N1BA 5DGSF 3ICMA 4H5EF 4LTZA 5AYPA 4JXNA 4KK2A 3V1XA 3DYFA 3IPIA 3N1VF 5ILHA 3WJOA 2OA6A 2E8TA 3V66A 1HXAA 3WEFA 4LFEA 3LZ9A 5JV2F 5B0LA 2ZCQA 4P0VA 4NFJF 3KB9A 4WK5A 3SAEA 4PVYF 2E92A 3WC9A 3N1WF 3ACXA 3PYBA 3G4FA 4JVJF 1YYQA 5DJVF 3ASXA 5IVGA 4E1EA 5ILKA 5C05A 4OGUA 3SDRA 5E8KA 5DHIA 3OACB 1RTRA 5IKAA 2Z4YA 2Z4WA 1YJ4A 5IK0A 1WY0A 2Q58A 3BNYA 5DGMF 3PDEA 4MC8A 5IMPA 1UBVA 3MZVA 1HM4A 3TS7A 4DEMF 5HNAA 1ZW5A 3P41A 3TC1A 3RYWA 2J1PA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3ICZ A;  3KRP B;  4NG6 A;  3N3D A;  1WL3 A;  1VG4 A;  3B7L A;  2E8X A;  4EA0 A;  4KVW A;  3ZMB A;  3ZOU A;  5JUZ F;  2FTZ A;  5B00 A;  4LFG A;  4RXE A;  4P0X A;  2F9K F;  4HD1 A;  2Q9Z A;  4F6X A;  4L2X F;  5DHK A;  4LUU A;  4QPF A;  3QQV A;  3VJA A;  3WEJ A;  1UBX A;  1WL2 A;  3DYH A;  3WCH A;  5IM1 A;  3WSB A;  5B02 A;  5B01 A;  2Z78 A;  3Q1O A;  4KQS A;  3AQ0 A;  3WCB A;  4JXY A;  5AFX A;  1VG2 A;  2J1O A;  1V4I A;  3CKE A;  3V1V A;  1YYU A;  2RAH A;  5ERN A;  4JZX A;  3KBK A;  3LVS A;  2Z4Z A;  4DHD A;  3ICK A;  3WSA A;  2FOR A;  3KRC A;  4KWD A;  4LLT A;  3IBA A;  2E93 A;  3VJD A;  4NFI F;  3VJB A;  3OAB B;  2ZCO A;  5IKH A;  2J5C A;  3VJE A;  2F89 F;  2AZK A;  5DJR F;  3WCI A;  5EAU A;  5JV0 F;  1V4E A;  3NPR A;  3DYG A;  4OKZ A;  5IK6 A;  4LZC A;  3LMD A;  3KRA A;  2PS6 A;  5HN7 A;  3RMG A;  1YV5 A;  4LZ0 A;  5IL3 A;  4LOB A;  3LDW A;  4KVY A;  1N21 A;  2DH4 A;  1N1Z A;  4EA1 A;  4MC3 A;  2H8O A;  3ICN A;  4LPG F;  3WCJ A;  2OPM A;  2Z52 A;  3WJN A;  5A0I A;  2E91 A;  2QIS A;  2ZCS A;  4H5D F;  3KRA B;  3LJI A;  2Z7I A;  1V4H A;  4E9Z A;  1YYT A;  3CC9 A;  3AQB B;  1JFA A;  4MC0 A;  4RXD A;  5B0K A;  5DW7 A;  4LPH F;  1WKZ A;  4XQR F;  4LA6 A;  1UBW A;  4KQ5 A;  5DGN F;  4FJQ A;  2Z50 A;  5B03 A;  2E8U A;  3LGZ B;  4JYX A;  5CG5 A;  5B0M A;  3RBM A;  5DIQ F;  4KUX A;  3VJC A;  2OPN A;  1YYS A;  5DZ2 A;  3P5R A;  4OMH A;  3LSN A;  3ADZ A;  4H5C F;  4XQT F;  3KRF A;  4GP2 A;  3ZMC A;  3N0G A;  4EA2 A;  2ONG A;  1RQI A;  2F8Z F;  3WCL A;  5IMI A;  2PS7 A;  1KIY A;  4OMG A;  4E9U A;  2ZEU A;  3M9U A;  1VG6 A;  5A0K A;  4GP1 A;  5JV1 F;  2P1C A;  4DWB A;  4DWG A;  2O1O A;  3WCG A;  3VJ9 A;  3ACW A;  2ZEV A;  3MAV A;  2PS5 A;  2I19 A;  4LIX A;  2F94 F;  3QKC A;  4LZ3 A;  3M0G A;  2AZL A;  4RYP A;  3WEH A;  3AE0 A;  3EGT A;  1YHL A;  2PS4 A;  4KFA A;  1UBY A;  2F92 F;  3Q2Z A;  5IMN A;  4LA5 A;  4LFV F;  5IL8 A;  4GAX A;  5DJP F;  5CG6 A;  3TFV A;  3AQC B;  3N49 F;  3P5P A;  3W7F A;  3N46 F;  3P8L A;  5AHU B;  1HX9 A;  3PKO A;  3KRO A;  3Q30 A;  3M02 A;  1YHK A;  4FP4 A;  3S4J A;  4DI5 A;  4KPJ A;  5A0J A;  3LEE A;  4P0W A;  3WCC A;  2AZJ A;  4QXS F;  3SDQ A;  4N9U A;  1HM7 A;  2Z4X A;  3PYA A;  4N1Z F;  1KIZ A;  4NUA A;  1N20 A;  3S9V A;  5E8H A;  3WCD A;  1DI1 A;  3KRO B;  3NPK A;  3VJ8 A;  5ER8 A;  5B0J A;  2E95 A;  3KRC B;  3EFQ A;  2AET A;  3LLW A;  5HN9 A;  5ILZ A;  3M00 A;  4Q23 A;  3N5H F;  5E8L A;  1WL0 A;  3N45 F;  3LG5 A;  3G4D A;  5AEL A;  4KPD A;  1VG3 A;  3WCE A;  3PH7 A;  1V4J A;  3NF2 A;  5ERO A;  3WCF A;  2F8C F;  3TFN A;  4OKM A;  4KVD A;  1HXG A;  4GA3 A;  4KVI A;  3WCA A;  3NRI A;  5KSX F;  5ILJ A;  1WMW A;  3N0F A;  3LGK A;  5ILY A;  5EAS A;  4DZW A;  2E8V A;  3OAC A;  2VF6 A;  5H9D A;  5ERM A;  1YHM A;  3ZCD A;  1JFG A;  4F62 A;  4DXJ A;  4K10 A;  4LXW A;  2E4O A;  3ZL6 A;  3KRP A;  3P8R A;  4LTV A;  1N22 A;  2E94 A;  4NKE A;  5HN8 A;  1N23 A;  1DGP A;  3WJK A;  3WEK A;  4UMJ A;  5ILI A;  1YYR A;  5B0I A;  2AEL A;  2OGD A;  2ZCR A;  1V4K A;  3KRF B;  3WEG A;  3WE9 A;  5IK9 A;  3APZ A;  4F6V A;  4RXC A;  2E90 A;  1HXC A;  1YQ7 A;  2Q9Y A;  5I1U A;  4NKF A;  3SDU A;  2E8W A;  3SDV A;  4PVX F;  4RXA A;  3Q2Q A;  1EZF A;  3SDT A;  3TFP A;  4JZB A;  2PS8 A;  3WCM A;  4XQS F;  3LOM A;  1N24 A;  3N5J F;  2EWG A;  3CP6 A;  2ZY1 A;  3OYR A;  4NFK F;  2F7M F;  2ONH A;  4ZQ8 A;  3EZ3 A;  4KQU A;  3UCA A;  5EAT A;  3RYE A;  3OAB A;  1VG7 A;  2AEK A;  4LLS A;  2Z7H A;  3WEI A;  3N3L F;  3N6K F;  3LK5 A;  4KKM A;  1RQJ A;  3ID0 A;  3ACY A;  1FPS A;  2Q80 A;  1WL1 A;  2Z4V A;  3BNX A;  5IN8 A;  5ILD A;  3M01 A;  5JA0 F;  1PS1 A;  4RNQ A;  1N1B A;  5DGS F;  3ICM A;  4H5E F;  4LTZ A;  5AYP A;  4JXN A;  4KK2 A;  3V1X A;  3DYF A;  3IPI A;  3N1V F;  5ILH A;  3WJO A;  2OA6 A;  2E8T A;  3V66 A;  1HXA A;  3WEF A;  4LFE A;  3LZ9 A;  5JV2 F;  5B0L A;  2ZCQ A;  4P0V A;  4NFJ F;  3KB9 A;  4WK5 A;  3SAE A;  4PVY F;  2E92 A;  3WC9 A;  3N1W F;  3ACX A;  3PYB A;  3G4F A;  4JVJ F;  1YYQ A;  5DJV F;  3ASX A;  5IVG A;  4E1E A;  5ILK A;  5C05 A;  4OGU A;  3SDR A;  5E8K A;  5DHI A;  3OAC B;  1RTR A;  5IKA A;  2Z4Y A;  2Z4W A;  1YJ4 A;  5IK0 A;  1WY0 A;  2Q58 A;  3BNY A;  5DGM F;  3PDE A;  4MC8 A;  5IMP A;  1UBV A;  3MZV A;  1HM4 A;  3TS7 A;  4DEM F;  5HNA A;  1ZW5 A;  3P41 A;  3TC1 A;  3RYW A;  2J1P A; 
#chains in the Genus database with same CATH topology
 3ICZ A;  3KRP B;  4NG6 A;  3N3D A;  1WL3 A;  1VG4 A;  3B7L A;  2E8X A;  4EA0 A;  4KVW A;  3ZMB A;  3ZOU A;  5JUZ F;  2FTZ A;  5B00 A;  4LFG A;  4RXE A;  4P0X A;  2F9K F;  4HD1 A;  2Q9Z A;  4F6X A;  4L2X F;  5DHK A;  4LUU A;  4QPF A;  3QQV A;  3VJA A;  3WEJ A;  1UBX A;  1WL2 A;  3DYH A;  3WCH A;  5IM1 A;  3WSB A;  5B02 A;  5B01 A;  2Z78 A;  3Q1O A;  4KQS A;  3AQ0 A;  3WCB A;  4JXY A;  5AFX A;  1VG2 A;  2J1O A;  1V4I A;  3CKE A;  3V1V A;  1YYU A;  2RAH A;  5ERN A;  4JZX A;  3KBK A;  3LVS A;  2Z4Z A;  4DHD A;  3ICK A;  3WSA A;  2FOR A;  3KRC A;  4KWD A;  4LLT A;  3IBA A;  2E93 A;  3VJD A;  4NFI F;  3VJB A;  3OAB B;  2ZCO A;  5IKH A;  2J5C A;  3VJE A;  2F89 F;  2AZK A;  5DJR F;  3WCI A;  5EAU A;  5JV0 F;  1V4E A;  3NPR A;  3DYG A;  4OKZ A;  5IK6 A;  4LZC A;  3LMD A;  3KRA A;  2PS6 A;  5HN7 A;  3RMG A;  1YV5 A;  4LZ0 A;  5IL3 A;  4LOB A;  3LDW A;  4KVY A;  1N21 A;  2DH4 A;  1N1Z A;  4EA1 A;  4MC3 A;  2H8O A;  3ICN A;  4LPG F;  3WCJ A;  2OPM A;  2Z52 A;  3WJN A;  5A0I A;  2E91 A;  2QIS A;  2ZCS A;  4H5D F;  3KRA B;  3LJI A;  2Z7I A;  1V4H A;  4E9Z A;  1YYT A;  3CC9 A;  3AQB B;  1JFA A;  4MC0 A;  4RXD A;  5B0K A;  5DW7 A;  4LPH F;  1WKZ A;  4XQR F;  4LA6 A;  1UBW A;  4KQ5 A;  5DGN F;  4FJQ A;  2Z50 A;  5B03 A;  2E8U A;  3LGZ B;  4JYX A;  5CG5 A;  5B0M A;  3RBM A;  5DIQ F;  4KUX A;  3VJC A;  2OPN A;  1YYS A;  5DZ2 A;  3P5R A;  4OMH A;  3LSN A;  3ADZ A;  4H5C F;  4XQT F;  3KRF A;  4GP2 A;  3ZMC A;  3N0G A;  4EA2 A;  2ONG A;  1RQI A;  2F8Z F;  3WCL A;  5IMI A;  2PS7 A;  1KIY A;  4OMG A;  4E9U A;  2ZEU A;  3M9U A;  1VG6 A;  5A0K A;  4GP1 A;  5JV1 F;  2P1C A;  4DWB A;  4DWG A;  2O1O A;  3WCG A;  3VJ9 A;  3ACW A;  2ZEV A;  3MAV A;  2PS5 A;  2I19 A;  4LIX A;  2F94 F;  3QKC A;  4LZ3 A;  3M0G A;  2AZL A;  4RYP A;  3WEH A;  3AE0 A;  3EGT A;  1YHL A;  2PS4 A;  4KFA A;  1UBY A;  2F92 F;  3Q2Z A;  5IMN A;  4LA5 A;  4LFV F;  5IL8 A;  4GAX A;  5DJP F;  5CG6 A;  3TFV A;  3AQC B;  3N49 F;  3P5P A;  3W7F A;  3N46 F;  3P8L A;  5AHU B;  1HX9 A;  3PKO A;  3KRO A;  3Q30 A;  3M02 A;  1YHK A;  4FP4 A;  3S4J A;  4DI5 A;  4KPJ A;  5A0J A;  3LEE A;  4P0W A;  3WCC A;  2AZJ A;  4QXS F;  3SDQ A;  4N9U A;  1HM7 A;  2Z4X A;  3PYA A;  4N1Z F;  1KIZ A;  4NUA A;  1N20 A;  3S9V A;  5E8H A;  3WCD A;  1DI1 A;  3KRO B;  3NPK A;  3VJ8 A;  5ER8 A;  5B0J A;  2E95 A;  3KRC B;  3EFQ A;  2AET A;  3LLW A;  5HN9 A;  5ILZ A;  3M00 A;  4Q23 A;  3N5H F;  5E8L A;  1WL0 A;  3N45 F;  3LG5 A;  3G4D A;  5AEL A;  4KPD A;  1VG3 A;  3WCE A;  3PH7 A;  1V4J A;  3NF2 A;  5ERO A;  3WCF A;  2F8C F;  3TFN A;  4OKM A;  4KVD A;  1HXG A;  4GA3 A;  4KVI A;  3WCA A;  3NRI A;  5KSX F;  5ILJ A;  1WMW A;  3N0F A;  3LGK A;  5ILY A;  5EAS A;  4DZW A;  2E8V A;  3OAC A;  2VF6 A;  5H9D A;  5ERM A;  1YHM A;  3ZCD A;  1JFG A;  4F62 A;  4DXJ A;  4K10 A;  4LXW A;  2E4O A;  3ZL6 A;  3KRP A;  3P8R A;  4LTV A;  1N22 A;  2E94 A;  4NKE A;  5HN8 A;  1N23 A;  1DGP A;  3WJK A;  3WEK A;  4UMJ A;  5ILI A;  1YYR A;  5B0I A;  2AEL A;  2OGD A;  2ZCR A;  1V4K A;  3KRF B;  3WEG A;  3WE9 A;  5IK9 A;  3APZ A;  4F6V A;  4RXC A;  2E90 A;  1HXC A;  1YQ7 A;  2Q9Y A;  5I1U A;  4NKF A;  3SDU A;  2E8W A;  3SDV A;  4PVX F;  4RXA A;  3Q2Q A;  1EZF A;  3SDT A;  3TFP A;  4JZB A;  2PS8 A;  3WCM A;  4XQS F;  3LOM A;  1N24 A;  3N5J F;  2EWG A;  3CP6 A;  2ZY1 A;  3OYR A;  4NFK F;  2F7M F;  2ONH A;  4ZQ8 A;  3EZ3 A;  4KQU A;  3UCA A;  5EAT A;  3RYE A;  3OAB A;  1VG7 A;  2AEK A;  4LLS A;  2Z7H A;  3WEI A;  3N3L F;  3N6K F;  3LK5 A;  4KKM A;  1RQJ A;  3ID0 A;  3ACY A;  1FPS A;  2Q80 A;  1WL1 A;  2Z4V A;  3BNX A;  5IN8 A;  5ILD A;  3M01 A;  5JA0 F;  1PS1 A;  4RNQ A;  1N1B A;  5DGS F;  3ICM A;  4H5E F;  4LTZ A;  5AYP A;  4JXN A;  4KK2 A;  3V1X A;  3DYF A;  3IPI A;  3N1V F;  5ILH A;  3WJO A;  2OA6 A;  2E8T A;  3V66 A;  1HXA A;  3WEF A;  4LFE A;  3LZ9 A;  5JV2 F;  5B0L A;  2ZCQ A;  4P0V A;  4NFJ F;  3KB9 A;  4WK5 A;  3SAE A;  4PVY F;  2E92 A;  3WC9 A;  3N1W F;  3ACX A;  3PYB A;  3G4F A;  4JVJ F;  1YYQ A;  5DJV F;  3ASX A;  5IVG A;  4E1E A;  5ILK A;  5C05 A;  4OGU A;  3SDR A;  5E8K A;  5DHI A;  3OAC B;  1RTR A;  5IKA A;  2Z4Y A;  2Z4W A;  1YJ4 A;  5IK0 A;  1WY0 A;  2Q58 A;  3BNY A;  5DGM F;  3PDE A;  4MC8 A;  5IMP A;  1UBV A;  3MZV A;  1HM4 A;  3TS7 A;  4DEM F;  5HNA A;  1ZW5 A;  3P41 A;  3TC1 A;  3RYW A;  2J1P A; 
#chains in the Genus database with same CATH homology
 3ICZ A;  3KRP B;  4NG6 A;  3N3D A;  1WL3 A;  1VG4 A;  3B7L A;  2E8X A;  4EA0 A;  4KVW A;  3ZMB A;  3ZOU A;  5JUZ F;  2FTZ A;  5B00 A;  4LFG A;  4RXE A;  4P0X A;  2F9K F;  4HD1 A;  2Q9Z A;  4F6X A;  4L2X F;  5DHK A;  4LUU A;  4QPF A;  3QQV A;  3VJA A;  3WEJ A;  1UBX A;  1WL2 A;  3DYH A;  3WCH A;  5IM1 A;  3WSB A;  5B02 A;  5B01 A;  2Z78 A;  3Q1O A;  4KQS A;  3AQ0 A;  3WCB A;  4JXY A;  5AFX A;  1VG2 A;  2J1O A;  1V4I A;  3CKE A;  3V1V A;  1YYU A;  2RAH A;  5ERN A;  4JZX A;  3KBK A;  3LVS A;  2Z4Z A;  4DHD A;  3ICK A;  3WSA A;  2FOR A;  3KRC A;  4KWD A;  4LLT A;  3IBA A;  2E93 A;  3VJD A;  4NFI F;  3VJB A;  3OAB B;  2ZCO A;  5IKH A;  2J5C A;  3VJE A;  2F89 F;  2AZK A;  5DJR F;  3WCI A;  5EAU A;  5JV0 F;  1V4E A;  3NPR A;  3DYG A;  4OKZ A;  5IK6 A;  4LZC A;  3LMD A;  3KRA A;  2PS6 A;  5HN7 A;  3RMG A;  1YV5 A;  4LZ0 A;  5IL3 A;  4LOB A;  3LDW A;  4KVY A;  1N21 A;  2DH4 A;  1N1Z A;  4EA1 A;  4MC3 A;  2H8O A;  3ICN A;  4LPG F;  3WCJ A;  2OPM A;  2Z52 A;  3WJN A;  5A0I A;  2E91 A;  2QIS A;  2ZCS A;  4H5D F;  3KRA B;  3LJI A;  2Z7I A;  1V4H A;  4E9Z A;  1YYT A;  3CC9 A;  3AQB B;  1JFA A;  4MC0 A;  4RXD A;  5B0K A;  5DW7 A;  4LPH F;  1WKZ A;  4XQR F;  4LA6 A;  1UBW A;  4KQ5 A;  5DGN F;  4FJQ A;  2Z50 A;  5B03 A;  2E8U A;  3LGZ B;  4JYX A;  5CG5 A;  5B0M A;  3RBM A;  5DIQ F;  4KUX A;  3VJC A;  2OPN A;  1YYS A;  5DZ2 A;  3P5R A;  4OMH A;  3LSN A;  3ADZ A;  4H5C F;  4XQT F;  3KRF A;  4GP2 A;  3ZMC A;  3N0G A;  4EA2 A;  2ONG A;  1RQI A;  2F8Z F;  3WCL A;  5IMI A;  2PS7 A;  1KIY A;  4OMG A;  4E9U A;  2ZEU A;  3M9U A;  1VG6 A;  5A0K A;  4GP1 A;  5JV1 F;  2P1C A;  4DWB A;  4DWG A;  2O1O A;  3WCG A;  3VJ9 A;  3ACW A;  2ZEV A;  3MAV A;  2PS5 A;  2I19 A;  4LIX A;  2F94 F;  3QKC A;  4LZ3 A;  3M0G A;  2AZL A;  4RYP A;  3WEH A;  3AE0 A;  3EGT A;  1YHL A;  2PS4 A;  4KFA A;  1UBY A;  2F92 F;  3Q2Z A;  5IMN A;  4LA5 A;  4LFV F;  5IL8 A;  4GAX A;  5DJP F;  5CG6 A;  3TFV A;  3AQC B;  3N49 F;  3P5P A;  3W7F A;  3N46 F;  3P8L A;  5AHU B;  1HX9 A;  3PKO A;  3KRO A;  3Q30 A;  3M02 A;  1YHK A;  4FP4 A;  3S4J A;  4DI5 A;  4KPJ A;  5A0J A;  3LEE A;  4P0W A;  3WCC A;  2AZJ A;  4QXS F;  3SDQ A;  4N9U A;  1HM7 A;  2Z4X A;  3PYA A;  4N1Z F;  1KIZ A;  4NUA A;  1N20 A;  3S9V A;  5E8H A;  3WCD A;  1DI1 A;  3KRO B;  3NPK A;  3VJ8 A;  5ER8 A;  5B0J A;  2E95 A;  3KRC B;  3EFQ A;  2AET A;  3LLW A;  5HN9 A;  5ILZ A;  3M00 A;  4Q23 A;  3N5H F;  5E8L A;  1WL0 A;  3N45 F;  3LG5 A;  3G4D A;  5AEL A;  4KPD A;  1VG3 A;  3WCE A;  3PH7 A;  1V4J A;  3NF2 A;  5ERO A;  3WCF A;  2F8C F;  3TFN A;  4OKM A;  4KVD A;  1HXG A;  4GA3 A;  4KVI A;  3WCA A;  3NRI A;  5KSX F;  5ILJ A;  1WMW A;  3N0F A;  3LGK A;  5ILY A;  5EAS A;  4DZW A;  2E8V A;  3OAC A;  2VF6 A;  5H9D A;  5ERM A;  1YHM A;  3ZCD A;  1JFG A;  4F62 A;  4DXJ A;  4K10 A;  4LXW A;  2E4O A;  3ZL6 A;  3KRP A;  3P8R A;  4LTV A;  1N22 A;  2E94 A;  4NKE A;  5HN8 A;  1N23 A;  1DGP A;  3WJK A;  3WEK A;  4UMJ A;  5ILI A;  1YYR A;  5B0I A;  2AEL A;  2OGD A;  2ZCR A;  1V4K A;  3KRF B;  3WEG A;  3WE9 A;  5IK9 A;  3APZ A;  4F6V A;  4RXC A;  2E90 A;  1HXC A;  1YQ7 A;  2Q9Y A;  5I1U A;  4NKF A;  3SDU A;  2E8W A;  3SDV A;  4PVX F;  4RXA A;  3Q2Q A;  1EZF A;  3SDT A;  3TFP A;  4JZB A;  2PS8 A;  3WCM A;  4XQS F;  3LOM A;  1N24 A;  3N5J F;  2EWG A;  3CP6 A;  2ZY1 A;  3OYR A;  4NFK F;  2F7M F;  2ONH A;  4ZQ8 A;  3EZ3 A;  4KQU A;  3UCA A;  5EAT A;  3RYE A;  3OAB A;  1VG7 A;  2AEK A;  4LLS A;  2Z7H A;  3WEI A;  3N3L F;  3N6K F;  3LK5 A;  4KKM A;  1RQJ A;  3ID0 A;  3ACY A;  1FPS A;  2Q80 A;  1WL1 A;  2Z4V A;  3BNX A;  5IN8 A;  5ILD A;  3M01 A;  5JA0 F;  1PS1 A;  4RNQ A;  1N1B A;  5DGS F;  3ICM A;  4H5E F;  4LTZ A;  5AYP A;  4JXN A;  4KK2 A;  3V1X A;  3DYF A;  3IPI A;  3N1V F;  5ILH A;  3WJO A;  2OA6 A;  2E8T A;  3V66 A;  1HXA A;  3WEF A;  4LFE A;  3LZ9 A;  5JV2 F;  5B0L A;  2ZCQ A;  4P0V A;  4NFJ F;  3KB9 A;  4WK5 A;  3SAE A;  4PVY F;  2E92 A;  3WC9 A;  3N1W F;  3ACX A;  3PYB A;  3G4F A;  4JVJ F;  1YYQ A;  5DJV F;  3ASX A;  5IVG A;  4E1E A;  5ILK A;  5C05 A;  4OGU A;  3SDR A;  5E8K A;  5DHI A;  3OAC B;  1RTR A;  5IKA A;  2Z4Y A;  2Z4W A;  1YJ4 A;  5IK0 A;  1WY0 A;  2Q58 A;  3BNY A;  5DGM F;  3PDE A;  4MC8 A;  5IMP A;  1UBV A;  3MZV A;  1HM4 A;  3TS7 A;  4DEM F;  5HNA A;  1ZW5 A;  3P41 A;  3TC1 A;  3RYW A;  2J1P A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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