3WSAA

The tuberculosis drug sq109 inhibits trypanosoma cruzi cell proliferation and acts synergistically with posaconazole
Total Genus 124
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
124
sequence length
334
structure length
329
Chain Sequence
LSSSLKTCYKYLNQTSRSFAAVIQALDGEMRNAVCIFYLVLRALDTLEDDMTISVEKKVPLLHNFHSFLYQPDWRFMESKEKDRQVLEDFPTISLEFRNLAEKYQTVIADICRRMGIGMAEFLDKHVTSEQEWDKYCHYVAGLVGIGLSRLFSASEFEDPLVGEDTERANSMGLFLQKTNIIRDYLEDQQGGREFWPQEVWSRYVKKLGDFALPENIDLAVQCLNELITNALHHIPDVITYLSRLRNQSVFNFCAIPQVMAIATLAACYNNQQVFKGAVLIVTLMMDATNMPAVKAIIYQYMEEIYHRIPDSNPSSSKTRQIISTIRTQ
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The Tuberculosis Drug SQ109 Inhibits Trypanosoma cruzi Cell Proliferation and acts Synergistically with Posaconazole
rcsb
molecule tags Transferase
source organism Homo sapiens
molecule keywords Squalene synthase
total genus 124
structure length 329
sequence length 334
chains with identical sequence B, C, D, E, F
ec nomenclature ec 2.5.1.21: Squalene synthase.
pdb deposition date 2014-03-05

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00494 SQS_PSY Squalene/phytoene synthase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.600.10 Mainly Alpha Orthogonal Bundle Farnesyl Diphosphate Synthase Farnesyl Diphosphate Synthase 3wsaA00
4DWBA 3ZL6A 2Z4VA 4QXSF 3N3DA 5AYPA 4E1EA 5B01A 4JVJF 3SAEA 3PH7A 1YV5A 4DI5A 3P5RA 4RNQA 5B0MA 1WKZA 4P0WA 5DZ2A 4RXAA 3AE0A 3IPIA 2Q9YA 3ICNA 2ZCOA 2OPNA 5AELA 1YYSA 4RYPA 3P5PA 3Q1OA 2FTZA 3W7FA 2Z50A 1VG7A 3SDVA 1ZW5A 2F9KF 3NF2A 5JV0F 3ICMA 2Q58A 3KRCB 4H5DF 5IM1A 3OYRA 3ZMCA 1VG2A 3ICKA 5E8HA 3UCAA 3N0GA 1RQIA 5CG5A 3LZ9A 2E8WA 5H9DA 3N1VF 4HD1A 2ZEVA 2AETA 3LOMA 3N3LF 4PVXF 4KQSA 1YJ4A 1RQJA 3PKOA 5E8KA 3QQVA 2PS4A 3NPKA 3AQBB 1HXGA 1V4KA 3SDQA 2H8OA 4LA5A 3RYEA 3PYBA 4XQSF 2AZLA 2DH4A 3DYGA 4NKFA 5IK0A 4EA2A 4E9UA 3N6KF 1YHLA 3ZCDA 4JZBA 5DW7A 2Z4YA 2O1OA 4NUAA 2E90A 2OA6A 3KRCA 4OKZA 2RAHA 4L2XF 5EASA 4H5EF 3VJDA 1YHMA 2Q9ZA 5HN7A 3EZ3A 5B0IA 1N24A 3LG5A 5IMPA 3AQCB 3N45F 3VJBA 3KRPB 3OABB 3SDUA 4F6XA 3KROA 4EA0A 5IKAA 2Z7HA 4XQRF 3Q2QA 4RXEA 2F89F 5DGSF 3KB9A 5B0LA 1RTRA 4NFKF 2F7MF 2F94F 3LGKA 4KPJA 4LA6A 5AFXA 3TFVA 3PDEA 3LDWA 4KKMA 4RXDA 5C05A 3TFNA 3WEKA 5IMNA 2E95A 4MC0A 5KSXF 3N46F 4JYXA 4DHDA 2AELA 1WMWA 4LFVF 3WCIA 3P41A 3M0GA 3ACWA 3OACB 3WCBA 3WCDA 3APZA 5I1UA 3LVSA 1N21A 5HN8A 5IL3A 5DGNF 1UBXA 3V66A 3WCGA 4P0XA 4NKEA 1JFGA 5JV2F 5B0JA 4FP4A 2ONHA 3KRFA 3KRPA 3LMDA 3OABA 5EROA 2OGDA 3DYHA 1VG3A 3SDTA 3ZOUA 5IK9A 1V4EA 3TS7A 3VJAA 5A0IA 2ONGA 2PS7A 4LZ0A 4KK2A 3WSBA 2E93A 3ASXA 2J1PA 4KVYA 1YYUA 3TC1A 5DGMF 1V4JA 2EWGA 1V4IA 2E92A 5ERNA 2AZJA 4RXCA 1YYTA 2F8CF 5B00A 4ZQ8A 1YYRA 3OACA 4KQ5A 2E8VA 3M02A 3ID0A 3WCLA 5IL8A 1N20A 2ZCSA 1VG6A 3MAVA 4JXNA 5IVGA 2E8UA 4MC3A 3WEIA 1DGPA 4OMGA 3TFPA 3WCCA 4KVIA 5JA0F 3AQ0A 4NFIF 3ACXA 4KUXA 2ZY1A 5DJPF 1EZFA 3WJKA 1YHKA 3M01A 3IBAA 2AEKA 5ILHA 2Q80A 3WCJA 5A0JA 4PVYF 1WY0A 3WJOA 1KIZA 1DI1A 5ER8A 3CP6A 3V1XA 3WE9A 1HXAA 5JUZF 5DHIA 3P8LA 3WEJA 3WEGA 5IMIA 2J5CA 3WJNA 1WL3A 3LSNA 5IK6A 2F92F 2QISA 2Z4XA 3DYFA 2OPMA 1HM7A 2F8ZF 1VG4A 3WSAA 5ERMA 1WL1A 2Z4WA 4K10A 4P0VA 2I19A 4LXWA 4GA3A 3VJ9A 3WCFA 5IKHA 4NFJF 5DJVF 4WK5A 5ILZA 4LPGF 4LTZA 2FORA 3N5JF 3G4DA 4E9ZA 1PS1A 1N23A 4F6VA 4KQUA 4LLTA 3LEEA 1YYQA 4DWGA 4GP1A 1WL2A 4LZCA 4DEMF 5EATA 1FPSA 2Z7IA 4NG6A 2PS8A 3MZVA 2ZEUA 2PS5A 3CKEA 4GP2A 4FJQA 2VF6A 3NPRA 3N5HF 5CG6A 5DJRF 5B03A 4N1ZF 5ILYA 5HNAA 4QPFA 3Q2ZA 4LFEA 2ZCQA 1UBYA 1V4HA 2J1OA 5E8LA 4N9UA 3KBKA 4LOBA 3WEFA 3ACYA 3S9VA 3RMGA 3PYAA 1N22A 3RBMA 4OGUA 3VJ8A 2E91A 1UBVA 4KPDA 4LZ3A 4LIXA 4XQTF 1YQ7A 3WEHA 5JV1F 5DHKA 4OKMA 3KRAB 1N1BA 3KROB 2PS6A 3LK5A 3Q30A 2Z52A 3CC9A 3WCHA 2E8XA 5IN8A 4Q23A 3VJEA 4LLSA 4DZWA 5DIQF 5ILJA 4LTVA 3M00A 3ZMBA 3N0FA 3V1VA 3BNYA 4DXJA 5AHUB 4LUUA 1HX9A 3LJIA 4EA1A 4MC8A 4LPHF 5B02A 3SDRA 3P8RA 3EGTA 3S4JA 3ICZA 3N1WF 4F62A 5HN9A 3WC9A 5B0KA 3LLWA 2AZKA 3ADZA 4JXYA 2E94A 1WL0A 3N49F 4OMHA 4LFGA 3WCMA 5EAUA 4KFAA 5ILIA 1JFAA 1HM4A 1N1ZA 4UMJA 4H5CF 3RYWA 1HXCA 3G4FA 3M9UA 2P1CA 3WCAA 3KRFB 3KRAA 4KVWA 4KWDA 2Z78A 3WCEA 1UBWA 4KVDA 2ZCRA 4GAXA 4JZXA 2Z4ZA 2E4OA 3BNXA 5A0KA 3EFQA 1KIYA 3B7LA 5ILKA 3NRIA 2E8TA 3VJCA 3QKCA 5ILDA 3LGZB
chains in the Genus database with same CATH superfamily
4DWBA 3ZL6A 2Z4VA 4QXSF 3N3DA 5AYPA 4E1EA 5B01A 4JVJF 3SAEA 3PH7A 1YV5A 4DI5A 3P5RA 4RNQA 5B0MA 1WKZA 4P0WA 5DZ2A 4RXAA 3AE0A 3IPIA 2Q9YA 3ICNA 2ZCOA 2OPNA 5AELA 1YYSA 4RYPA 3P5PA 3Q1OA 2FTZA 3W7FA 2Z50A 1VG7A 3SDVA 1ZW5A 2F9KF 3NF2A 5JV0F 3ICMA 2Q58A 3KRCB 4H5DF 5IM1A 3OYRA 3ZMCA 1VG2A 3ICKA 5E8HA 3UCAA 3N0GA 1RQIA 5CG5A 3LZ9A 2E8WA 5H9DA 3N1VF 4HD1A 2ZEVA 2AETA 3LOMA 3N3LF 4PVXF 4KQSA 1YJ4A 1RQJA 3PKOA 5E8KA 3QQVA 2PS4A 3NPKA 3AQBB 1HXGA 1V4KA 3SDQA 2H8OA 4LA5A 3RYEA 3PYBA 4XQSF 2AZLA 2DH4A 3DYGA 4NKFA 5IK0A 4EA2A 4E9UA 3N6KF 1YHLA 3ZCDA 4JZBA 5DW7A 2Z4YA 2O1OA 4NUAA 2E90A 2OA6A 3KRCA 4OKZA 2RAHA 4L2XF 5EASA 4H5EF 3VJDA 1YHMA 2Q9ZA 5HN7A 3EZ3A 5B0IA 1N24A 3LG5A 5IMPA 3AQCB 3N45F 3VJBA 3KRPB 3OABB 3SDUA 4F6XA 3KROA 4EA0A 5IKAA 2Z7HA 4XQRF 3Q2QA 4RXEA 2F89F 5DGSF 3KB9A 5B0LA 1RTRA 4NFKF 2F7MF 2F94F 3LGKA 4KPJA 4LA6A 5AFXA 3TFVA 3PDEA 3LDWA 4KKMA 4RXDA 5C05A 3TFNA 3WEKA 5IMNA 2E95A 4MC0A 5KSXF 3N46F 4JYXA 4DHDA 2AELA 1WMWA 4LFVF 3WCIA 3P41A 3M0GA 3ACWA 3OACB 3WCBA 3WCDA 3APZA 5I1UA 3LVSA 1N21A 5HN8A 5IL3A 5DGNF 1UBXA 3V66A 3WCGA 4P0XA 4NKEA 1JFGA 5JV2F 5B0JA 4FP4A 2ONHA 3KRFA 3KRPA 3LMDA 3OABA 5EROA 2OGDA 3DYHA 1VG3A 3SDTA 3ZOUA 5IK9A 1V4EA 3TS7A 3VJAA 5A0IA 2ONGA 2PS7A 4LZ0A 4KK2A 3WSBA 2E93A 3ASXA 2J1PA 4KVYA 1YYUA 3TC1A 5DGMF 1V4JA 2EWGA 1V4IA 2E92A 5ERNA 2AZJA 4RXCA 1YYTA 2F8CF 5B00A 4ZQ8A 1YYRA 3OACA 4KQ5A 2E8VA 3M02A 3ID0A 3WCLA 5IL8A 1N20A 2ZCSA 1VG6A 3MAVA 4JXNA 5IVGA 2E8UA 4MC3A 3WEIA 1DGPA 4OMGA 3TFPA 3WCCA 4KVIA 5JA0F 3AQ0A 4NFIF 3ACXA 4KUXA 2ZY1A 5DJPF 1EZFA 3WJKA 1YHKA 3M01A 3IBAA 2AEKA 5ILHA 2Q80A 3WCJA 5A0JA 4PVYF 1WY0A 3WJOA 1KIZA 1DI1A 5ER8A 3CP6A 3V1XA 3WE9A 1HXAA 5JUZF 5DHIA 3P8LA 3WEJA 3WEGA 5IMIA 2J5CA 3WJNA 1WL3A 3LSNA 5IK6A 2F92F 2QISA 2Z4XA 3DYFA 2OPMA 1HM7A 2F8ZF 1VG4A 3WSAA 5ERMA 1WL1A 2Z4WA 4K10A 4P0VA 2I19A 4LXWA 4GA3A 3VJ9A 3WCFA 5IKHA 4NFJF 5DJVF 4WK5A 5ILZA 4LPGF 4LTZA 2FORA 3N5JF 3G4DA 4E9ZA 1PS1A 1N23A 4F6VA 4KQUA 4LLTA 3LEEA 1YYQA 4DWGA 4GP1A 1WL2A 4LZCA 4DEMF 5EATA 1FPSA 2Z7IA 4NG6A 2PS8A 3MZVA 2ZEUA 2PS5A 3CKEA 4GP2A 4FJQA 2VF6A 3NPRA 3N5HF 5CG6A 5DJRF 5B03A 4N1ZF 5ILYA 5HNAA 4QPFA 3Q2ZA 4LFEA 2ZCQA 1UBYA 1V4HA 2J1OA 5E8LA 4N9UA 3KBKA 4LOBA 3WEFA 3ACYA 3S9VA 3RMGA 3PYAA 1N22A 3RBMA 4OGUA 3VJ8A 2E91A 1UBVA 4KPDA 4LZ3A 4LIXA 4XQTF 1YQ7A 3WEHA 5JV1F 5DHKA 4OKMA 3KRAB 1N1BA 3KROB 2PS6A 3LK5A 3Q30A 2Z52A 3CC9A 3WCHA 2E8XA 5IN8A 4Q23A 3VJEA 4LLSA 4DZWA 5DIQF 5ILJA 4LTVA 3M00A 3ZMBA 3N0FA 3V1VA 3BNYA 4DXJA 5AHUB 4LUUA 1HX9A 3LJIA 4EA1A 4MC8A 4LPHF 5B02A 3SDRA 3P8RA 3EGTA 3S4JA 3ICZA 3N1WF 4F62A 5HN9A 3WC9A 5B0KA 3LLWA 2AZKA 3ADZA 4JXYA 2E94A 1WL0A 3N49F 4OMHA 4LFGA 3WCMA 5EAUA 4KFAA 5ILIA 1JFAA 1HM4A 1N1ZA 4UMJA 4H5CF 3RYWA 1HXCA 3G4FA 3M9UA 2P1CA 3WCAA 3KRFB 3KRAA 4KVWA 4KWDA 2Z78A 3WCEA 1UBWA 4KVDA 2ZCRA 4GAXA 4JZXA 2Z4ZA 2E4OA 3BNXA 5A0KA 3EFQA 1KIYA 3B7LA 5ILKA 3NRIA 2E8TA 3VJCA 3QKCA 5ILDA 3LGZB
chains in the Genus database with same CATH topology
4DWBA 3ZL6A 2Z4VA 4QXSF 3N3DA 5AYPA 4E1EA 5B01A 4JVJF 3SAEA 3PH7A 1YV5A 4DI5A 3P5RA 4RNQA 5B0MA 1WKZA 4P0WA 5DZ2A 4RXAA 3AE0A 3IPIA 2Q9YA 3ICNA 2ZCOA 2OPNA 5AELA 1YYSA 4RYPA 3P5PA 3Q1OA 2FTZA 3W7FA 2Z50A 1VG7A 3SDVA 1ZW5A 2F9KF 3NF2A 5JV0F 3ICMA 2Q58A 3KRCB 4H5DF 5IM1A 3OYRA 3ZMCA 1VG2A 3ICKA 5E8HA 3UCAA 3N0GA 1RQIA 5CG5A 3LZ9A 2E8WA 5H9DA 3N1VF 4HD1A 2ZEVA 2AETA 3LOMA 3N3LF 4PVXF 4KQSA 1YJ4A 1RQJA 3PKOA 5E8KA 3QQVA 2PS4A 3NPKA 3AQBB 1HXGA 1V4KA 3SDQA 2H8OA 4LA5A 3RYEA 3PYBA 4XQSF 2AZLA 2DH4A 3DYGA 4NKFA 5IK0A 4EA2A 4E9UA 3N6KF 1YHLA 3ZCDA 4JZBA 5DW7A 2Z4YA 2O1OA 4NUAA 2E90A 2OA6A 3KRCA 4OKZA 2RAHA 4L2XF 5EASA 4H5EF 3VJDA 1YHMA 2Q9ZA 5HN7A 3EZ3A 5B0IA 1N24A 3LG5A 5IMPA 3AQCB 3N45F 3VJBA 3KRPB 3OABB 3SDUA 4F6XA 3KROA 4EA0A 5IKAA 2Z7HA 4XQRF 3Q2QA 4RXEA 2F89F 5DGSF 3KB9A 5B0LA 1RTRA 4NFKF 2F7MF 2F94F 3LGKA 4KPJA 4LA6A 5AFXA 3TFVA 3PDEA 3LDWA 4KKMA 4RXDA 5C05A 3TFNA 3WEKA 5IMNA 2E95A 4MC0A 5KSXF 3N46F 4JYXA 4DHDA 2AELA 1WMWA 4LFVF 3WCIA 3P41A 3M0GA 3ACWA 3OACB 3WCBA 3WCDA 3APZA 5I1UA 3LVSA 1N21A 5HN8A 5IL3A 5DGNF 1UBXA 3V66A 3WCGA 4P0XA 4NKEA 1JFGA 5JV2F 5B0JA 4FP4A 2ONHA 3KRFA 3KRPA 3LMDA 3OABA 5EROA 2OGDA 3DYHA 1VG3A 3SDTA 3ZOUA 5IK9A 1V4EA 3TS7A 3VJAA 5A0IA 2ONGA 2PS7A 4LZ0A 4KK2A 3WSBA 2E93A 3ASXA 2J1PA 4KVYA 1YYUA 3TC1A 5DGMF 1V4JA 2EWGA 1V4IA 2E92A 5ERNA 2AZJA 4RXCA 1YYTA 2F8CF 5B00A 4ZQ8A 1YYRA 3OACA 4KQ5A 2E8VA 3M02A 3ID0A 3WCLA 5IL8A 1N20A 2ZCSA 1VG6A 3MAVA 4JXNA 5IVGA 2E8UA 4MC3A 3WEIA 1DGPA 4OMGA 3TFPA 3WCCA 4KVIA 5JA0F 3AQ0A 4NFIF 3ACXA 4KUXA 2ZY1A 5DJPF 1EZFA 3WJKA 1YHKA 3M01A 3IBAA 2AEKA 5ILHA 2Q80A 3WCJA 5A0JA 4PVYF 1WY0A 3WJOA 1KIZA 1DI1A 5ER8A 3CP6A 3V1XA 3WE9A 1HXAA 5JUZF 5DHIA 3P8LA 3WEJA 3WEGA 5IMIA 2J5CA 3WJNA 1WL3A 3LSNA 5IK6A 2F92F 2QISA 2Z4XA 3DYFA 2OPMA 1HM7A 2F8ZF 1VG4A 3WSAA 5ERMA 1WL1A 2Z4WA 4K10A 4P0VA 2I19A 4LXWA 4GA3A 3VJ9A 3WCFA 5IKHA 4NFJF 5DJVF 4WK5A 5ILZA 4LPGF 4LTZA 2FORA 3N5JF 3G4DA 4E9ZA 1PS1A 1N23A 4F6VA 4KQUA 4LLTA 3LEEA 1YYQA 4DWGA 4GP1A 1WL2A 4LZCA 4DEMF 5EATA 1FPSA 2Z7IA 4NG6A 2PS8A 3MZVA 2ZEUA 2PS5A 3CKEA 4GP2A 4FJQA 2VF6A 3NPRA 3N5HF 5CG6A 5DJRF 5B03A 4N1ZF 5ILYA 5HNAA 4QPFA 3Q2ZA 4LFEA 2ZCQA 1UBYA 1V4HA 2J1OA 5E8LA 4N9UA 3KBKA 4LOBA 3WEFA 3ACYA 3S9VA 3RMGA 3PYAA 1N22A 3RBMA 4OGUA 3VJ8A 2E91A 1UBVA 4KPDA 4LZ3A 4LIXA 4XQTF 1YQ7A 3WEHA 5JV1F 5DHKA 4OKMA 3KRAB 1N1BA 3KROB 2PS6A 3LK5A 3Q30A 2Z52A 3CC9A 3WCHA 2E8XA 5IN8A 4Q23A 3VJEA 4LLSA 4DZWA 5DIQF 5ILJA 4LTVA 3M00A 3ZMBA 3N0FA 3V1VA 3BNYA 4DXJA 5AHUB 4LUUA 1HX9A 3LJIA 4EA1A 4MC8A 4LPHF 5B02A 3SDRA 3P8RA 3EGTA 3S4JA 3ICZA 3N1WF 4F62A 5HN9A 3WC9A 5B0KA 3LLWA 2AZKA 3ADZA 4JXYA 2E94A 1WL0A 3N49F 4OMHA 4LFGA 3WCMA 5EAUA 4KFAA 5ILIA 1JFAA 1HM4A 1N1ZA 4UMJA 4H5CF 3RYWA 1HXCA 3G4FA 3M9UA 2P1CA 3WCAA 3KRFB 3KRAA 4KVWA 4KWDA 2Z78A 3WCEA 1UBWA 4KVDA 2ZCRA 4GAXA 4JZXA 2Z4ZA 2E4OA 3BNXA 5A0KA 3EFQA 1KIYA 3B7LA 5ILKA 3NRIA 2E8TA 3VJCA 3QKCA 5ILDA 3LGZB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4DWB A;  3ZL6 A;  2Z4V A;  4QXS F;  3N3D A;  5AYP A;  4E1E A;  5B01 A;  4JVJ F;  3SAE A;  3PH7 A;  1YV5 A;  4DI5 A;  3P5R A;  4RNQ A;  5B0M A;  1WKZ A;  4P0W A;  5DZ2 A;  4RXA A;  3AE0 A;  3IPI A;  2Q9Y A;  3ICN A;  2ZCO A;  2OPN A;  5AEL A;  1YYS A;  4RYP A;  3P5P A;  3Q1O A;  2FTZ A;  3W7F A;  2Z50 A;  1VG7 A;  3SDV A;  1ZW5 A;  2F9K F;  3NF2 A;  5JV0 F;  3ICM A;  2Q58 A;  3KRC B;  4H5D F;  5IM1 A;  3OYR A;  3ZMC A;  1VG2 A;  3ICK A;  5E8H A;  3UCA A;  3N0G A;  1RQI A;  5CG5 A;  3LZ9 A;  2E8W A;  5H9D A;  3N1V F;  4HD1 A;  2ZEV A;  2AET A;  3LOM A;  3N3L F;  4PVX F;  4KQS A;  1YJ4 A;  1RQJ A;  3PKO A;  5E8K A;  3QQV A;  2PS4 A;  3NPK A;  3AQB B;  1HXG A;  1V4K A;  3SDQ A;  2H8O A;  4LA5 A;  3RYE A;  3PYB A;  4XQS F;  2AZL A;  2DH4 A;  3DYG A;  4NKF A;  5IK0 A;  4EA2 A;  4E9U A;  3N6K F;  1YHL A;  3ZCD A;  4JZB A;  5DW7 A;  2Z4Y A;  2O1O A;  4NUA A;  2E90 A;  2OA6 A;  3KRC A;  4OKZ A;  2RAH A;  4L2X F;  5EAS A;  4H5E F;  3VJD A;  1YHM A;  2Q9Z A;  5HN7 A;  3EZ3 A;  5B0I A;  1N24 A;  3LG5 A;  5IMP A;  3AQC B;  3N45 F;  3VJB A;  3KRP B;  3OAB B;  3SDU A;  4F6X A;  3KRO A;  4EA0 A;  5IKA A;  2Z7H A;  4XQR F;  3Q2Q A;  4RXE A;  2F89 F;  5DGS F;  3KB9 A;  5B0L A;  1RTR A;  4NFK F;  2F7M F;  2F94 F;  3LGK A;  4KPJ A;  4LA6 A;  5AFX A;  3TFV A;  3PDE A;  3LDW A;  4KKM A;  4RXD A;  5C05 A;  3TFN A;  3WEK A;  5IMN A;  2E95 A;  4MC0 A;  5KSX F;  3N46 F;  4JYX A;  4DHD A;  2AEL A;  1WMW A;  4LFV F;  3WCI A;  3P41 A;  3M0G A;  3ACW A;  3OAC B;  3WCB A;  3WCD A;  3APZ A;  5I1U A;  3LVS A;  1N21 A;  5HN8 A;  5IL3 A;  5DGN F;  1UBX A;  3V66 A;  3WCG A;  4P0X A;  4NKE A;  1JFG A;  5JV2 F;  5B0J A;  4FP4 A;  2ONH A;  3KRF A;  3KRP A;  3LMD A;  3OAB A;  5ERO A;  2OGD A;  3DYH A;  1VG3 A;  3SDT A;  3ZOU A;  5IK9 A;  1V4E A;  3TS7 A;  3VJA A;  5A0I A;  2ONG A;  2PS7 A;  4LZ0 A;  4KK2 A;  3WSB A;  2E93 A;  3ASX A;  2J1P A;  4KVY A;  1YYU A;  3TC1 A;  5DGM F;  1V4J A;  2EWG A;  1V4I A;  2E92 A;  5ERN A;  2AZJ A;  4RXC A;  1YYT A;  2F8C F;  5B00 A;  4ZQ8 A;  1YYR A;  3OAC A;  4KQ5 A;  2E8V A;  3M02 A;  3ID0 A;  3WCL A;  5IL8 A;  1N20 A;  2ZCS A;  1VG6 A;  3MAV A;  4JXN A;  5IVG A;  2E8U A;  4MC3 A;  3WEI A;  1DGP A;  4OMG A;  3TFP A;  3WCC A;  4KVI A;  5JA0 F;  3AQ0 A;  4NFI F;  3ACX A;  4KUX A;  2ZY1 A;  5DJP F;  1EZF A;  3WJK A;  1YHK A;  3M01 A;  3IBA A;  2AEK A;  5ILH A;  2Q80 A;  3WCJ A;  5A0J A;  4PVY F;  1WY0 A;  3WJO A;  1KIZ A;  1DI1 A;  5ER8 A;  3CP6 A;  3V1X A;  3WE9 A;  1HXA A;  5JUZ F;  5DHI A;  3P8L A;  3WEJ A;  3WEG A;  5IMI A;  2J5C A;  3WJN A;  1WL3 A;  3LSN A;  5IK6 A;  2F92 F;  2QIS A;  2Z4X A;  3DYF A;  2OPM A;  1HM7 A;  2F8Z F;  1VG4 A;  3WSA A;  5ERM A;  1WL1 A;  2Z4W A;  4K10 A;  4P0V A;  2I19 A;  4LXW A;  4GA3 A;  3VJ9 A;  3WCF A;  5IKH A;  4NFJ F;  5DJV F;  4WK5 A;  5ILZ A;  4LPG F;  4LTZ A;  2FOR A;  3N5J F;  3G4D A;  4E9Z A;  1PS1 A;  1N23 A;  4F6V A;  4KQU A;  4LLT A;  3LEE A;  1YYQ A;  4DWG A;  4GP1 A;  1WL2 A;  4LZC A;  4DEM F;  5EAT A;  1FPS A;  2Z7I A;  4NG6 A;  2PS8 A;  3MZV A;  2ZEU A;  2PS5 A;  3CKE A;  4GP2 A;  4FJQ A;  2VF6 A;  3NPR A;  3N5H F;  5CG6 A;  5DJR F;  5B03 A;  4N1Z F;  5ILY A;  5HNA A;  4QPF A;  3Q2Z A;  4LFE A;  2ZCQ A;  1UBY A;  1V4H A;  2J1O A;  5E8L A;  4N9U A;  3KBK A;  4LOB A;  3WEF A;  3ACY A;  3S9V A;  3RMG A;  3PYA A;  1N22 A;  3RBM A;  4OGU A;  3VJ8 A;  2E91 A;  1UBV A;  4KPD A;  4LZ3 A;  4LIX A;  4XQT F;  1YQ7 A;  3WEH A;  5JV1 F;  5DHK A;  4OKM A;  3KRA B;  1N1B A;  3KRO B;  2PS6 A;  3LK5 A;  3Q30 A;  2Z52 A;  3CC9 A;  3WCH A;  2E8X A;  5IN8 A;  4Q23 A;  3VJE A;  4LLS A;  4DZW A;  5DIQ F;  5ILJ A;  4LTV A;  3M00 A;  3ZMB A;  3N0F A;  3V1V A;  3BNY A;  4DXJ A;  5AHU B;  4LUU A;  1HX9 A;  3LJI A;  4EA1 A;  4MC8 A;  4LPH F;  5B02 A;  3SDR A;  3P8R A;  3EGT A;  3S4J A;  3ICZ A;  3N1W F;  4F62 A;  5HN9 A;  3WC9 A;  5B0K A;  3LLW A;  2AZK A;  3ADZ A;  4JXY A;  2E94 A;  1WL0 A;  3N49 F;  4OMH A;  4LFG A;  3WCM A;  5EAU A;  4KFA A;  5ILI A;  1JFA A;  1HM4 A;  1N1Z A;  4UMJ A;  4H5C F;  3RYW A;  1HXC A;  3G4F A;  3M9U A;  2P1C A;  3WCA A;  3KRF B;  3KRA A;  4KVW A;  4KWD A;  2Z78 A;  3WCE A;  1UBW A;  4KVD A;  2ZCR A;  4GAX A;  4JZX A;  2Z4Z A;  2E4O A;  3BNX A;  5A0K A;  3EFQ A;  1KIY A;  3B7L A;  5ILK A;  3NRI A;  2E8T A;  3VJC A;  3QKC A;  5ILD A;  3LGZ B; 
#chains in the Genus database with same CATH topology
 4DWB A;  3ZL6 A;  2Z4V A;  4QXS F;  3N3D A;  5AYP A;  4E1E A;  5B01 A;  4JVJ F;  3SAE A;  3PH7 A;  1YV5 A;  4DI5 A;  3P5R A;  4RNQ A;  5B0M A;  1WKZ A;  4P0W A;  5DZ2 A;  4RXA A;  3AE0 A;  3IPI A;  2Q9Y A;  3ICN A;  2ZCO A;  2OPN A;  5AEL A;  1YYS A;  4RYP A;  3P5P A;  3Q1O A;  2FTZ A;  3W7F A;  2Z50 A;  1VG7 A;  3SDV A;  1ZW5 A;  2F9K F;  3NF2 A;  5JV0 F;  3ICM A;  2Q58 A;  3KRC B;  4H5D F;  5IM1 A;  3OYR A;  3ZMC A;  1VG2 A;  3ICK A;  5E8H A;  3UCA A;  3N0G A;  1RQI A;  5CG5 A;  3LZ9 A;  2E8W A;  5H9D A;  3N1V F;  4HD1 A;  2ZEV A;  2AET A;  3LOM A;  3N3L F;  4PVX F;  4KQS A;  1YJ4 A;  1RQJ A;  3PKO A;  5E8K A;  3QQV A;  2PS4 A;  3NPK A;  3AQB B;  1HXG A;  1V4K A;  3SDQ A;  2H8O A;  4LA5 A;  3RYE A;  3PYB A;  4XQS F;  2AZL A;  2DH4 A;  3DYG A;  4NKF A;  5IK0 A;  4EA2 A;  4E9U A;  3N6K F;  1YHL A;  3ZCD A;  4JZB A;  5DW7 A;  2Z4Y A;  2O1O A;  4NUA A;  2E90 A;  2OA6 A;  3KRC A;  4OKZ A;  2RAH A;  4L2X F;  5EAS A;  4H5E F;  3VJD A;  1YHM A;  2Q9Z A;  5HN7 A;  3EZ3 A;  5B0I A;  1N24 A;  3LG5 A;  5IMP A;  3AQC B;  3N45 F;  3VJB A;  3KRP B;  3OAB B;  3SDU A;  4F6X A;  3KRO A;  4EA0 A;  5IKA A;  2Z7H A;  4XQR F;  3Q2Q A;  4RXE A;  2F89 F;  5DGS F;  3KB9 A;  5B0L A;  1RTR A;  4NFK F;  2F7M F;  2F94 F;  3LGK A;  4KPJ A;  4LA6 A;  5AFX A;  3TFV A;  3PDE A;  3LDW A;  4KKM A;  4RXD A;  5C05 A;  3TFN A;  3WEK A;  5IMN A;  2E95 A;  4MC0 A;  5KSX F;  3N46 F;  4JYX A;  4DHD A;  2AEL A;  1WMW A;  4LFV F;  3WCI A;  3P41 A;  3M0G A;  3ACW A;  3OAC B;  3WCB A;  3WCD A;  3APZ A;  5I1U A;  3LVS A;  1N21 A;  5HN8 A;  5IL3 A;  5DGN F;  1UBX A;  3V66 A;  3WCG A;  4P0X A;  4NKE A;  1JFG A;  5JV2 F;  5B0J A;  4FP4 A;  2ONH A;  3KRF A;  3KRP A;  3LMD A;  3OAB A;  5ERO A;  2OGD A;  3DYH A;  1VG3 A;  3SDT A;  3ZOU A;  5IK9 A;  1V4E A;  3TS7 A;  3VJA A;  5A0I A;  2ONG A;  2PS7 A;  4LZ0 A;  4KK2 A;  3WSB A;  2E93 A;  3ASX A;  2J1P A;  4KVY A;  1YYU A;  3TC1 A;  5DGM F;  1V4J A;  2EWG A;  1V4I A;  2E92 A;  5ERN A;  2AZJ A;  4RXC A;  1YYT A;  2F8C F;  5B00 A;  4ZQ8 A;  1YYR A;  3OAC A;  4KQ5 A;  2E8V A;  3M02 A;  3ID0 A;  3WCL A;  5IL8 A;  1N20 A;  2ZCS A;  1VG6 A;  3MAV A;  4JXN A;  5IVG A;  2E8U A;  4MC3 A;  3WEI A;  1DGP A;  4OMG A;  3TFP A;  3WCC A;  4KVI A;  5JA0 F;  3AQ0 A;  4NFI F;  3ACX A;  4KUX A;  2ZY1 A;  5DJP F;  1EZF A;  3WJK A;  1YHK A;  3M01 A;  3IBA A;  2AEK A;  5ILH A;  2Q80 A;  3WCJ A;  5A0J A;  4PVY F;  1WY0 A;  3WJO A;  1KIZ A;  1DI1 A;  5ER8 A;  3CP6 A;  3V1X A;  3WE9 A;  1HXA A;  5JUZ F;  5DHI A;  3P8L A;  3WEJ A;  3WEG A;  5IMI A;  2J5C A;  3WJN A;  1WL3 A;  3LSN A;  5IK6 A;  2F92 F;  2QIS A;  2Z4X A;  3DYF A;  2OPM A;  1HM7 A;  2F8Z F;  1VG4 A;  3WSA A;  5ERM A;  1WL1 A;  2Z4W A;  4K10 A;  4P0V A;  2I19 A;  4LXW A;  4GA3 A;  3VJ9 A;  3WCF A;  5IKH A;  4NFJ F;  5DJV F;  4WK5 A;  5ILZ A;  4LPG F;  4LTZ A;  2FOR A;  3N5J F;  3G4D A;  4E9Z A;  1PS1 A;  1N23 A;  4F6V A;  4KQU A;  4LLT A;  3LEE A;  1YYQ A;  4DWG A;  4GP1 A;  1WL2 A;  4LZC A;  4DEM F;  5EAT A;  1FPS A;  2Z7I A;  4NG6 A;  2PS8 A;  3MZV A;  2ZEU A;  2PS5 A;  3CKE A;  4GP2 A;  4FJQ A;  2VF6 A;  3NPR A;  3N5H F;  5CG6 A;  5DJR F;  5B03 A;  4N1Z F;  5ILY A;  5HNA A;  4QPF A;  3Q2Z A;  4LFE A;  2ZCQ A;  1UBY A;  1V4H A;  2J1O A;  5E8L A;  4N9U A;  3KBK A;  4LOB A;  3WEF A;  3ACY A;  3S9V A;  3RMG A;  3PYA A;  1N22 A;  3RBM A;  4OGU A;  3VJ8 A;  2E91 A;  1UBV A;  4KPD A;  4LZ3 A;  4LIX A;  4XQT F;  1YQ7 A;  3WEH A;  5JV1 F;  5DHK A;  4OKM A;  3KRA B;  1N1B A;  3KRO B;  2PS6 A;  3LK5 A;  3Q30 A;  2Z52 A;  3CC9 A;  3WCH A;  2E8X A;  5IN8 A;  4Q23 A;  3VJE A;  4LLS A;  4DZW A;  5DIQ F;  5ILJ A;  4LTV A;  3M00 A;  3ZMB A;  3N0F A;  3V1V A;  3BNY A;  4DXJ A;  5AHU B;  4LUU A;  1HX9 A;  3LJI A;  4EA1 A;  4MC8 A;  4LPH F;  5B02 A;  3SDR A;  3P8R A;  3EGT A;  3S4J A;  3ICZ A;  3N1W F;  4F62 A;  5HN9 A;  3WC9 A;  5B0K A;  3LLW A;  2AZK A;  3ADZ A;  4JXY A;  2E94 A;  1WL0 A;  3N49 F;  4OMH A;  4LFG A;  3WCM A;  5EAU A;  4KFA A;  5ILI A;  1JFA A;  1HM4 A;  1N1Z A;  4UMJ A;  4H5C F;  3RYW A;  1HXC A;  3G4F A;  3M9U A;  2P1C A;  3WCA A;  3KRF B;  3KRA A;  4KVW A;  4KWD A;  2Z78 A;  3WCE A;  1UBW A;  4KVD A;  2ZCR A;  4GAX A;  4JZX A;  2Z4Z A;  2E4O A;  3BNX A;  5A0K A;  3EFQ A;  1KIY A;  3B7L A;  5ILK A;  3NRI A;  2E8T A;  3VJC A;  3QKC A;  5ILD A;  3LGZ B; 
#chains in the Genus database with same CATH homology
 4DWB A;  3ZL6 A;  2Z4V A;  4QXS F;  3N3D A;  5AYP A;  4E1E A;  5B01 A;  4JVJ F;  3SAE A;  3PH7 A;  1YV5 A;  4DI5 A;  3P5R A;  4RNQ A;  5B0M A;  1WKZ A;  4P0W A;  5DZ2 A;  4RXA A;  3AE0 A;  3IPI A;  2Q9Y A;  3ICN A;  2ZCO A;  2OPN A;  5AEL A;  1YYS A;  4RYP A;  3P5P A;  3Q1O A;  2FTZ A;  3W7F A;  2Z50 A;  1VG7 A;  3SDV A;  1ZW5 A;  2F9K F;  3NF2 A;  5JV0 F;  3ICM A;  2Q58 A;  3KRC B;  4H5D F;  5IM1 A;  3OYR A;  3ZMC A;  1VG2 A;  3ICK A;  5E8H A;  3UCA A;  3N0G A;  1RQI A;  5CG5 A;  3LZ9 A;  2E8W A;  5H9D A;  3N1V F;  4HD1 A;  2ZEV A;  2AET A;  3LOM A;  3N3L F;  4PVX F;  4KQS A;  1YJ4 A;  1RQJ A;  3PKO A;  5E8K A;  3QQV A;  2PS4 A;  3NPK A;  3AQB B;  1HXG A;  1V4K A;  3SDQ A;  2H8O A;  4LA5 A;  3RYE A;  3PYB A;  4XQS F;  2AZL A;  2DH4 A;  3DYG A;  4NKF A;  5IK0 A;  4EA2 A;  4E9U A;  3N6K F;  1YHL A;  3ZCD A;  4JZB A;  5DW7 A;  2Z4Y A;  2O1O A;  4NUA A;  2E90 A;  2OA6 A;  3KRC A;  4OKZ A;  2RAH A;  4L2X F;  5EAS A;  4H5E F;  3VJD A;  1YHM A;  2Q9Z A;  5HN7 A;  3EZ3 A;  5B0I A;  1N24 A;  3LG5 A;  5IMP A;  3AQC B;  3N45 F;  3VJB A;  3KRP B;  3OAB B;  3SDU A;  4F6X A;  3KRO A;  4EA0 A;  5IKA A;  2Z7H A;  4XQR F;  3Q2Q A;  4RXE A;  2F89 F;  5DGS F;  3KB9 A;  5B0L A;  1RTR A;  4NFK F;  2F7M F;  2F94 F;  3LGK A;  4KPJ A;  4LA6 A;  5AFX A;  3TFV A;  3PDE A;  3LDW A;  4KKM A;  4RXD A;  5C05 A;  3TFN A;  3WEK A;  5IMN A;  2E95 A;  4MC0 A;  5KSX F;  3N46 F;  4JYX A;  4DHD A;  2AEL A;  1WMW A;  4LFV F;  3WCI A;  3P41 A;  3M0G A;  3ACW A;  3OAC B;  3WCB A;  3WCD A;  3APZ A;  5I1U A;  3LVS A;  1N21 A;  5HN8 A;  5IL3 A;  5DGN F;  1UBX A;  3V66 A;  3WCG A;  4P0X A;  4NKE A;  1JFG A;  5JV2 F;  5B0J A;  4FP4 A;  2ONH A;  3KRF A;  3KRP A;  3LMD A;  3OAB A;  5ERO A;  2OGD A;  3DYH A;  1VG3 A;  3SDT A;  3ZOU A;  5IK9 A;  1V4E A;  3TS7 A;  3VJA A;  5A0I A;  2ONG A;  2PS7 A;  4LZ0 A;  4KK2 A;  3WSB A;  2E93 A;  3ASX A;  2J1P A;  4KVY A;  1YYU A;  3TC1 A;  5DGM F;  1V4J A;  2EWG A;  1V4I A;  2E92 A;  5ERN A;  2AZJ A;  4RXC A;  1YYT A;  2F8C F;  5B00 A;  4ZQ8 A;  1YYR A;  3OAC A;  4KQ5 A;  2E8V A;  3M02 A;  3ID0 A;  3WCL A;  5IL8 A;  1N20 A;  2ZCS A;  1VG6 A;  3MAV A;  4JXN A;  5IVG A;  2E8U A;  4MC3 A;  3WEI A;  1DGP A;  4OMG A;  3TFP A;  3WCC A;  4KVI A;  5JA0 F;  3AQ0 A;  4NFI F;  3ACX A;  4KUX A;  2ZY1 A;  5DJP F;  1EZF A;  3WJK A;  1YHK A;  3M01 A;  3IBA A;  2AEK A;  5ILH A;  2Q80 A;  3WCJ A;  5A0J A;  4PVY F;  1WY0 A;  3WJO A;  1KIZ A;  1DI1 A;  5ER8 A;  3CP6 A;  3V1X A;  3WE9 A;  1HXA A;  5JUZ F;  5DHI A;  3P8L A;  3WEJ A;  3WEG A;  5IMI A;  2J5C A;  3WJN A;  1WL3 A;  3LSN A;  5IK6 A;  2F92 F;  2QIS A;  2Z4X A;  3DYF A;  2OPM A;  1HM7 A;  2F8Z F;  1VG4 A;  3WSA A;  5ERM A;  1WL1 A;  2Z4W A;  4K10 A;  4P0V A;  2I19 A;  4LXW A;  4GA3 A;  3VJ9 A;  3WCF A;  5IKH A;  4NFJ F;  5DJV F;  4WK5 A;  5ILZ A;  4LPG F;  4LTZ A;  2FOR A;  3N5J F;  3G4D A;  4E9Z A;  1PS1 A;  1N23 A;  4F6V A;  4KQU A;  4LLT A;  3LEE A;  1YYQ A;  4DWG A;  4GP1 A;  1WL2 A;  4LZC A;  4DEM F;  5EAT A;  1FPS A;  2Z7I A;  4NG6 A;  2PS8 A;  3MZV A;  2ZEU A;  2PS5 A;  3CKE A;  4GP2 A;  4FJQ A;  2VF6 A;  3NPR A;  3N5H F;  5CG6 A;  5DJR F;  5B03 A;  4N1Z F;  5ILY A;  5HNA A;  4QPF A;  3Q2Z A;  4LFE A;  2ZCQ A;  1UBY A;  1V4H A;  2J1O A;  5E8L A;  4N9U A;  3KBK A;  4LOB A;  3WEF A;  3ACY A;  3S9V A;  3RMG A;  3PYA A;  1N22 A;  3RBM A;  4OGU A;  3VJ8 A;  2E91 A;  1UBV A;  4KPD A;  4LZ3 A;  4LIX A;  4XQT F;  1YQ7 A;  3WEH A;  5JV1 F;  5DHK A;  4OKM A;  3KRA B;  1N1B A;  3KRO B;  2PS6 A;  3LK5 A;  3Q30 A;  2Z52 A;  3CC9 A;  3WCH A;  2E8X A;  5IN8 A;  4Q23 A;  3VJE A;  4LLS A;  4DZW A;  5DIQ F;  5ILJ A;  4LTV A;  3M00 A;  3ZMB A;  3N0F A;  3V1V A;  3BNY A;  4DXJ A;  5AHU B;  4LUU A;  1HX9 A;  3LJI A;  4EA1 A;  4MC8 A;  4LPH F;  5B02 A;  3SDR A;  3P8R A;  3EGT A;  3S4J A;  3ICZ A;  3N1W F;  4F62 A;  5HN9 A;  3WC9 A;  5B0K A;  3LLW A;  2AZK A;  3ADZ A;  4JXY A;  2E94 A;  1WL0 A;  3N49 F;  4OMH A;  4LFG A;  3WCM A;  5EAU A;  4KFA A;  5ILI A;  1JFA A;  1HM4 A;  1N1Z A;  4UMJ A;  4H5C F;  3RYW A;  1HXC A;  3G4F A;  3M9U A;  2P1C A;  3WCA A;  3KRF B;  3KRA A;  4KVW A;  4KWD A;  2Z78 A;  3WCE A;  1UBW A;  4KVD A;  2ZCR A;  4GAX A;  4JZX A;  2Z4Z A;  2E4O A;  3BNX A;  5A0K A;  3EFQ A;  1KIY A;  3B7L A;  5ILK A;  3NRI A;  2E8T A;  3VJC A;  3QKC A;  5ILD A;  3LGZ B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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