4DZWA

Crystal structure of trypanosome cruzi farnesyl diphosphate synthase in complex with [2-(cyclohexylamino)ethane-1,1-diyl]bisphosphonic acid and mg2+
Total Genus 138
50100150200250300350020406080100120140
Genus TraceResidueGenus

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
138
sequence length
359
structure length
359
Chain Sequence
ASMERFLSVYDEVQAFLLDQLQSKYEIDPNRARYLRIMMDTTCLGGKYFRGMTVVNVAEGFLAVTQHDEATKERILHDACVGGWMIEFLQAHYLVEDDIMDGSVMRRGKPCWYRFPGVTTQCAINDGIILKSWTQIMAWHYFADRPFLKDLLCLFQKVDYATAVGQMYDVTSMCDSNKLDPEVAQPMTTDFAEFTPAIYKRIVKYKTTFYTYLLPLVMGLFVSEAAASVEMNLVERVAHLIGEYFQVQDDVMDCFTPPEQLGKVGTDIEDAKCSWLAVTFLGKANAAQVAEFKANYGDKDPAKVAVVKRLYSEANLQADFAAYEAEVVREVESLIEQLKVKSPTFAESVAVVWEKTHKR
5010015020025030035035030025020015010050
020406080100120Genus Matrix

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
AH1 (2-26)AH3 (50-65)AH2 (30-44)AH5 (121-143)S1 (106-107)AH4 (70-102)TIV3 (143-146)AH6 (148-172)EMPTYS2 (110-111)TIV1 (106-109)AH9 (259-262)3H1 (113-115)TI1 (116-119)TIV2 (117-120)AH7 (197-223)TI8 (269-272)TI2 (172-175)3H2 (177-179)TI5 (192-195)TI4 (189-192)AH14 (344-359)TI6 (226-229)AH8 (232-255)TI7 (227-230)AH13 (317-341)TIV4 (267-270)TIV5 (268-271)TII1 (296-299)AH10 (276-283)AH12 (302-315)AH11 (287-295)TIV6 (341-344)TI3 (181-184)Updating...
connected with : NaN
molecule tags Transferase/transferase inhibitor
source organism Trypanosoma cruzi
publication title Design, synthesis, calorimetry, and crystallographic analysis of 2-alkylaminoethyl-1,1-bisphosphonates as inhibitors of Trypanosoma cruzi farnesyl diphosphate synthase.
pubmed doi rcsb
molecule keywords Farnesyl pyrophosphate synthase
total genus 138
structure length 359
sequence length 359
ec nomenclature ec 2.5.1.10: (2E,6E)-farnesyl diphosphate synthase.
pdb deposition date 2012-03-01

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00348 polyprenyl_synt Polyprenyl synthetase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.600.10 Mainly Alpha Orthogonal Bundle Farnesyl Diphosphate Synthase Farnesyl Diphosphate Synthase 4dzwA00
5DGNF 5AHUB 1UBYA 5DHIA 2AEKA 3APZA 4KPDA 3TFPA 4F6XA 2F7MF 3Q30A 2FORA 3VJEA 2F89F 4RXEA 4LA6A 3VJAA 5IN8A 5EATA 4E1EA 3N3LF 3MAVA 3AQ0A 3IPIA 4PVXF 4DHDA 3LMDA 1KIZA 3VJBA 2OPMA 3PYAA 5JV1F 5IK9A 5B02A 4XQRF 5JUZF 4KK2A 5DGSF 3WJOA 1N23A 1VG6A 3ACYA 3EGTA 2OA6A 2F9KF 4LLSA 2ZEUA 1RTRA 3P41A 3TC1A 1HX9A 4KQUA 1JFGA 5DW7A 1RQJA 2Q9ZA 3ID0A 2PS7A 4GA3A 3SDUA 2AZKA 4P0XA 2EWGA 3KRFA 4JVJF 4KVIA 3ZCDA 3ICZA 4NKFA 3BNXA 4KQSA 4LA5A 3P5RA 1YJ4A 2PS4A 4E9UA 5E8HA 2J1OA 5JV2F 3TFNA 5DZ2A 2Z4WA 3BNYA 5IKAA 4NFKF 3OYRA 3AE0A 5ERMA 3WJNA 4LOBA 2E92A 5KSXF 4MC0A 2AELA 5HNAA 2Q58A 2DH4A 3N5HF 4DWGA 1V4HA 5ILDA 5DJPF 3WCDA 4KFAA 3VJCA 4DZWA 4K10A 3ACWA 4MC3A 4P0WA 5B0MA 3WCCA 1N22A 3AQCB 1WMWA 1DGPA 3ASXA 2Z52A 3VJ8A 1YYSA 3N49F 4KVYA 2AZJA 5ILYA 4FJQA 3LOMA 3VJ9A 5AYPA 1V4IA 1VG2A 3WCBA 3LZ9A 1KIYA 3WCHA 3WEGA 5IL3A 3QKCA 4OMHA 3WEKA 4RXAA 2F8CF 4EA0A 2Q9YA 3RYEA 5DJRF 1VG4A 2F8ZF 3DYFA 1HXAA 1WL3A 1YYQA 3ICNA 3AQBB 3PH7A 5I1UA 1HM4A 3TFVA 3OACB 2E8WA 4H5CF 4N9UA 4P0VA 4LTZA 4KUXA 4KWDA 4WK5A 5AFXA 3DYHA 3WCFA 3OABA 2AZLA 3WSAA 3P8LA 1PS1A 3SDRA 3SAEA 3KRCA 1JFAA 3SDVA 2PS6A 5IK6A 5B0LA 3TS7A 1UBWA 2OGDA 2Z7IA 3M01A 3WCLA 1FPSA 4JXNA 2O1OA 3S9VA 1VG7A 5IK0A 2Q80A 4NG6A 5IL8A 2ONHA 1HXCA 4QXSF 3LGZB 3NF2A 4RXCA 2ONGA 3ZMBA 3KRPB 4JXYA 2E8TA 3WEJA 5EASA 1YHLA 4LZ0A 3P5PA 2E94A 5JA0F 3LK5A 3N6KF 1V4KA 5C05A 2E91A 1N24A 2QISA 3UCAA 3EZ3A 4LFVF 1UBXA 2F94F 4DXJA 4F62A 3ADZA 5ERNA 4LLTA 3KRPA 2Z4XA 5DJVF 5E8KA 4L2XF 3IBAA 3Q1OA 3KROB 3Q2ZA 3W7FA 4H5EF 3N0GA 4XQSF 4NKEA 3ICMA 4LFGA 3MZVA 3ACXA 3V66A 1YQ7A 3CP6A 3S4JA 1WKZA 3LEEA 4KQ5A 2H8OA 2J1PA 3KROA 2PS8A 3B7LA 5B01A 3WEFA 1YYRA 2AETA 2E4OA 4KKMA 1ZW5A 5ER8A 4LZCA 3QQVA 3LVSA 2Z50A 4E9ZA 1WL2A 5IMPA 2E8UA 1N20A 2P1CA 4JYXA 5HN8A 4NFIF 3N46F 4HD1A 1YHKA 2Z7HA 3RMGA 5JV0F 3N3DA 5ILKA 4GP2A 1V4EA 2ZCRA 1RQIA 5B0IA 3RYWA 3NPRA 3V1VA 3ZL6A 5CG5A 4ZQ8A 3ICKA 2E95A 2Z4YA 4JZBA 2E8XA 3WE9A 2PS5A 4DI5A 4F6VA 5B0KA 3KRAB 4LPHF 3DYGA 3M9UA 2ZEVA 3WCEA 4DWBA 3OACA 1N1ZA 5A0KA 3LJIA 2ZCOA 4GAXA 5HN7A 1N1BA 4UMJA 3WCMA 2E90A 4KVDA 3N45F 5B0JA 3V1XA 3KRAA 3LLWA 1HM7A 3N1VF 3LDWA 3LSNA 1YV5A 1V4JA 5B00A 1N21A 4MC8A 2Z4VA 3ZOUA 5E8LA 3LG5A 3CKEA 3P8RA 2ZCSA 4LZ3A 5ILJA 3WCJA 3WCAA 5A0JA 4OKZA 3LGKA 5DHKA 5EAUA 3CC9A 4LPGF 3KRFB 1WY0A 4DEMF 1DI1A 2Z4ZA 1HXGA 4LXWA 3WSBA 4EA1A 3SDQA 2ZY1A 3G4FA 4PVYF 3WJKA 3M0GA 2FTZA 2E93A 5DIQF 5IVGA 2F92F 5HN9A 4EA2A 2ZCQA 2OPNA 3G4DA 1WL1A 4OMGA 1WL0A 4JZXA 3NPKA 2RAHA 3VJDA 5B03A 5ILIA 5A0IA 4OKMA 5H9DA 4RXDA 5AELA 4XQTF 4OGUA 1YHMA 4QPFA 5CG6A 2J5CA 3M02A 4LUUA 1VG3A 3WEHA 3Q2QA 4NUAA 1EZFA 5EROA 4LFEA 4H5DF 3PDEA 4LTVA 1YYUA 2Z78A 4NFJF 5IM1A 3KBKA 3PYBA 5ILZA 3N1WF 1UBVA 3ZMCA 2I19A 5IMIA 3EFQA 4N1ZF 5DGMF 3OABB 4LIXA 2E8VA 1YYTA 3WEIA 2VF6A 3SDTA 3KB9A 4KPJA 3NRIA 3KRCB 3RBMA 5IKHA 3N5JF 4GP1A 3WCIA 3M00A 5IMNA 3WC9A 4FP4A 3WCGA 4KVWA 4RNQA 5ILHA 4Q23A 3N0FA 4RYPA 3PKOA
chains in the Genus database with same CATH superfamily
5DGNF 5AHUB 1UBYA 5DHIA 2AEKA 3APZA 4KPDA 3TFPA 4F6XA 2F7MF 3Q30A 2FORA 3VJEA 2F89F 4RXEA 4LA6A 3VJAA 5IN8A 5EATA 4E1EA 3N3LF 3MAVA 3AQ0A 3IPIA 4PVXF 4DHDA 3LMDA 1KIZA 3VJBA 2OPMA 3PYAA 5JV1F 5IK9A 5B02A 4XQRF 5JUZF 4KK2A 5DGSF 3WJOA 1N23A 1VG6A 3ACYA 3EGTA 2OA6A 2F9KF 4LLSA 2ZEUA 1RTRA 3P41A 3TC1A 1HX9A 4KQUA 1JFGA 5DW7A 1RQJA 2Q9ZA 3ID0A 2PS7A 4GA3A 3SDUA 2AZKA 4P0XA 2EWGA 3KRFA 4JVJF 4KVIA 3ZCDA 3ICZA 4NKFA 3BNXA 4KQSA 4LA5A 3P5RA 1YJ4A 2PS4A 4E9UA 5E8HA 2J1OA 5JV2F 3TFNA 5DZ2A 2Z4WA 3BNYA 5IKAA 4NFKF 3OYRA 3AE0A 5ERMA 3WJNA 4LOBA 2E92A 5KSXF 4MC0A 2AELA 5HNAA 2Q58A 2DH4A 3N5HF 4DWGA 1V4HA 5ILDA 5DJPF 3WCDA 4KFAA 3VJCA 4DZWA 4K10A 3ACWA 4MC3A 4P0WA 5B0MA 3WCCA 1N22A 3AQCB 1WMWA 1DGPA 3ASXA 2Z52A 3VJ8A 1YYSA 3N49F 4KVYA 2AZJA 5ILYA 4FJQA 3LOMA 3VJ9A 5AYPA 1V4IA 1VG2A 3WCBA 3LZ9A 1KIYA 3WCHA 3WEGA 5IL3A 3QKCA 4OMHA 3WEKA 4RXAA 2F8CF 4EA0A 2Q9YA 3RYEA 5DJRF 1VG4A 2F8ZF 3DYFA 1HXAA 1WL3A 1YYQA 3ICNA 3AQBB 3PH7A 5I1UA 1HM4A 3TFVA 3OACB 2E8WA 4H5CF 4N9UA 4P0VA 4LTZA 4KUXA 4KWDA 4WK5A 5AFXA 3DYHA 3WCFA 3OABA 2AZLA 3WSAA 3P8LA 1PS1A 3SDRA 3SAEA 3KRCA 1JFAA 3SDVA 2PS6A 5IK6A 5B0LA 3TS7A 1UBWA 2OGDA 2Z7IA 3M01A 3WCLA 1FPSA 4JXNA 2O1OA 3S9VA 1VG7A 5IK0A 2Q80A 4NG6A 5IL8A 2ONHA 1HXCA 4QXSF 3LGZB 3NF2A 4RXCA 2ONGA 3ZMBA 3KRPB 4JXYA 2E8TA 3WEJA 5EASA 1YHLA 4LZ0A 3P5PA 2E94A 5JA0F 3LK5A 3N6KF 1V4KA 5C05A 2E91A 1N24A 2QISA 3UCAA 3EZ3A 4LFVF 1UBXA 2F94F 4DXJA 4F62A 3ADZA 5ERNA 4LLTA 3KRPA 2Z4XA 5DJVF 5E8KA 4L2XF 3IBAA 3Q1OA 3KROB 3Q2ZA 3W7FA 4H5EF 3N0GA 4XQSF 4NKEA 3ICMA 4LFGA 3MZVA 3ACXA 3V66A 1YQ7A 3CP6A 3S4JA 1WKZA 3LEEA 4KQ5A 2H8OA 2J1PA 3KROA 2PS8A 3B7LA 5B01A 3WEFA 1YYRA 2AETA 2E4OA 4KKMA 1ZW5A 5ER8A 4LZCA 3QQVA 3LVSA 2Z50A 4E9ZA 1WL2A 5IMPA 2E8UA 1N20A 2P1CA 4JYXA 5HN8A 4NFIF 3N46F 4HD1A 1YHKA 2Z7HA 3RMGA 5JV0F 3N3DA 5ILKA 4GP2A 1V4EA 2ZCRA 1RQIA 5B0IA 3RYWA 3NPRA 3V1VA 3ZL6A 5CG5A 4ZQ8A 3ICKA 2E95A 2Z4YA 4JZBA 2E8XA 3WE9A 2PS5A 4DI5A 4F6VA 5B0KA 3KRAB 4LPHF 3DYGA 3M9UA 2ZEVA 3WCEA 4DWBA 3OACA 1N1ZA 5A0KA 3LJIA 2ZCOA 4GAXA 5HN7A 1N1BA 4UMJA 3WCMA 2E90A 4KVDA 3N45F 5B0JA 3V1XA 3KRAA 3LLWA 1HM7A 3N1VF 3LDWA 3LSNA 1YV5A 1V4JA 5B00A 1N21A 4MC8A 2Z4VA 3ZOUA 5E8LA 3LG5A 3CKEA 3P8RA 2ZCSA 4LZ3A 5ILJA 3WCJA 3WCAA 5A0JA 4OKZA 3LGKA 5DHKA 5EAUA 3CC9A 4LPGF 3KRFB 1WY0A 4DEMF 1DI1A 2Z4ZA 1HXGA 4LXWA 3WSBA 4EA1A 3SDQA 2ZY1A 3G4FA 4PVYF 3WJKA 3M0GA 2FTZA 2E93A 5DIQF 5IVGA 2F92F 5HN9A 4EA2A 2ZCQA 2OPNA 3G4DA 1WL1A 4OMGA 1WL0A 4JZXA 3NPKA 2RAHA 3VJDA 5B03A 5ILIA 5A0IA 4OKMA 5H9DA 4RXDA 5AELA 4XQTF 4OGUA 1YHMA 4QPFA 5CG6A 2J5CA 3M02A 4LUUA 1VG3A 3WEHA 3Q2QA 4NUAA 1EZFA 5EROA 4LFEA 4H5DF 3PDEA 4LTVA 1YYUA 2Z78A 4NFJF 5IM1A 3KBKA 3PYBA 5ILZA 3N1WF 1UBVA 3ZMCA 2I19A 5IMIA 3EFQA 4N1ZF 5DGMF 3OABB 4LIXA 2E8VA 1YYTA 3WEIA 2VF6A 3SDTA 3KB9A 4KPJA 3NRIA 3KRCB 3RBMA 5IKHA 3N5JF 4GP1A 3WCIA 3M00A 5IMNA 3WC9A 4FP4A 3WCGA 4KVWA 4RNQA 5ILHA 4Q23A 3N0FA 4RYPA 3PKOA
chains in the Genus database with same CATH topology
5DGNF 5AHUB 1UBYA 5DHIA 2AEKA 3APZA 4KPDA 3TFPA 4F6XA 2F7MF 3Q30A 2FORA 3VJEA 2F89F 4RXEA 4LA6A 3VJAA 5IN8A 5EATA 4E1EA 3N3LF 3MAVA 3AQ0A 3IPIA 4PVXF 4DHDA 3LMDA 1KIZA 3VJBA 2OPMA 3PYAA 5JV1F 5IK9A 5B02A 4XQRF 5JUZF 4KK2A 5DGSF 3WJOA 1N23A 1VG6A 3ACYA 3EGTA 2OA6A 2F9KF 4LLSA 2ZEUA 1RTRA 3P41A 3TC1A 1HX9A 4KQUA 1JFGA 5DW7A 1RQJA 2Q9ZA 3ID0A 2PS7A 4GA3A 3SDUA 2AZKA 4P0XA 2EWGA 3KRFA 4JVJF 4KVIA 3ZCDA 3ICZA 4NKFA 3BNXA 4KQSA 4LA5A 3P5RA 1YJ4A 2PS4A 4E9UA 5E8HA 2J1OA 5JV2F 3TFNA 5DZ2A 2Z4WA 3BNYA 5IKAA 4NFKF 3OYRA 3AE0A 5ERMA 3WJNA 4LOBA 2E92A 5KSXF 4MC0A 2AELA 5HNAA 2Q58A 2DH4A 3N5HF 4DWGA 1V4HA 5ILDA 5DJPF 3WCDA 4KFAA 3VJCA 4DZWA 4K10A 3ACWA 4MC3A 4P0WA 5B0MA 3WCCA 1N22A 3AQCB 1WMWA 1DGPA 3ASXA 2Z52A 3VJ8A 1YYSA 3N49F 4KVYA 2AZJA 5ILYA 4FJQA 3LOMA 3VJ9A 5AYPA 1V4IA 1VG2A 3WCBA 3LZ9A 1KIYA 3WCHA 3WEGA 5IL3A 3QKCA 4OMHA 3WEKA 4RXAA 2F8CF 4EA0A 2Q9YA 3RYEA 5DJRF 1VG4A 2F8ZF 3DYFA 1HXAA 1WL3A 1YYQA 3ICNA 3AQBB 3PH7A 5I1UA 1HM4A 3TFVA 3OACB 2E8WA 4H5CF 4N9UA 4P0VA 4LTZA 4KUXA 4KWDA 4WK5A 5AFXA 3DYHA 3WCFA 3OABA 2AZLA 3WSAA 3P8LA 1PS1A 3SDRA 3SAEA 3KRCA 1JFAA 3SDVA 2PS6A 5IK6A 5B0LA 3TS7A 1UBWA 2OGDA 2Z7IA 3M01A 3WCLA 1FPSA 4JXNA 2O1OA 3S9VA 1VG7A 5IK0A 2Q80A 4NG6A 5IL8A 2ONHA 1HXCA 4QXSF 3LGZB 3NF2A 4RXCA 2ONGA 3ZMBA 3KRPB 4JXYA 2E8TA 3WEJA 5EASA 1YHLA 4LZ0A 3P5PA 2E94A 5JA0F 3LK5A 3N6KF 1V4KA 5C05A 2E91A 1N24A 2QISA 3UCAA 3EZ3A 4LFVF 1UBXA 2F94F 4DXJA 4F62A 3ADZA 5ERNA 4LLTA 3KRPA 2Z4XA 5DJVF 5E8KA 4L2XF 3IBAA 3Q1OA 3KROB 3Q2ZA 3W7FA 4H5EF 3N0GA 4XQSF 4NKEA 3ICMA 4LFGA 3MZVA 3ACXA 3V66A 1YQ7A 3CP6A 3S4JA 1WKZA 3LEEA 4KQ5A 2H8OA 2J1PA 3KROA 2PS8A 3B7LA 5B01A 3WEFA 1YYRA 2AETA 2E4OA 4KKMA 1ZW5A 5ER8A 4LZCA 3QQVA 3LVSA 2Z50A 4E9ZA 1WL2A 5IMPA 2E8UA 1N20A 2P1CA 4JYXA 5HN8A 4NFIF 3N46F 4HD1A 1YHKA 2Z7HA 3RMGA 5JV0F 3N3DA 5ILKA 4GP2A 1V4EA 2ZCRA 1RQIA 5B0IA 3RYWA 3NPRA 3V1VA 3ZL6A 5CG5A 4ZQ8A 3ICKA 2E95A 2Z4YA 4JZBA 2E8XA 3WE9A 2PS5A 4DI5A 4F6VA 5B0KA 3KRAB 4LPHF 3DYGA 3M9UA 2ZEVA 3WCEA 4DWBA 3OACA 1N1ZA 5A0KA 3LJIA 2ZCOA 4GAXA 5HN7A 1N1BA 4UMJA 3WCMA 2E90A 4KVDA 3N45F 5B0JA 3V1XA 3KRAA 3LLWA 1HM7A 3N1VF 3LDWA 3LSNA 1YV5A 1V4JA 5B00A 1N21A 4MC8A 2Z4VA 3ZOUA 5E8LA 3LG5A 3CKEA 3P8RA 2ZCSA 4LZ3A 5ILJA 3WCJA 3WCAA 5A0JA 4OKZA 3LGKA 5DHKA 5EAUA 3CC9A 4LPGF 3KRFB 1WY0A 4DEMF 1DI1A 2Z4ZA 1HXGA 4LXWA 3WSBA 4EA1A 3SDQA 2ZY1A 3G4FA 4PVYF 3WJKA 3M0GA 2FTZA 2E93A 5DIQF 5IVGA 2F92F 5HN9A 4EA2A 2ZCQA 2OPNA 3G4DA 1WL1A 4OMGA 1WL0A 4JZXA 3NPKA 2RAHA 3VJDA 5B03A 5ILIA 5A0IA 4OKMA 5H9DA 4RXDA 5AELA 4XQTF 4OGUA 1YHMA 4QPFA 5CG6A 2J5CA 3M02A 4LUUA 1VG3A 3WEHA 3Q2QA 4NUAA 1EZFA 5EROA 4LFEA 4H5DF 3PDEA 4LTVA 1YYUA 2Z78A 4NFJF 5IM1A 3KBKA 3PYBA 5ILZA 3N1WF 1UBVA 3ZMCA 2I19A 5IMIA 3EFQA 4N1ZF 5DGMF 3OABB 4LIXA 2E8VA 1YYTA 3WEIA 2VF6A 3SDTA 3KB9A 4KPJA 3NRIA 3KRCB 3RBMA 5IKHA 3N5JF 4GP1A 3WCIA 3M00A 5IMNA 3WC9A 4FP4A 3WCGA 4KVWA 4RNQA 5ILHA 4Q23A 3N0FA 4RYPA 3PKOA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5DGN F;  5AHU B;  1UBY A;  5DHI A;  2AEK A;  3APZ A;  4KPD A;  3TFP A;  4F6X A;  2F7M F;  3Q30 A;  2FOR A;  3VJE A;  2F89 F;  4RXE A;  4LA6 A;  3VJA A;  5IN8 A;  5EAT A;  4E1E A;  3N3L F;  3MAV A;  3AQ0 A;  3IPI A;  4PVX F;  4DHD A;  3LMD A;  1KIZ A;  3VJB A;  2OPM A;  3PYA A;  5JV1 F;  5IK9 A;  5B02 A;  4XQR F;  5JUZ F;  4KK2 A;  5DGS F;  3WJO A;  1N23 A;  1VG6 A;  3ACY A;  3EGT A;  2OA6 A;  2F9K F;  4LLS A;  2ZEU A;  1RTR A;  3P41 A;  3TC1 A;  1HX9 A;  4KQU A;  1JFG A;  5DW7 A;  1RQJ A;  2Q9Z A;  3ID0 A;  2PS7 A;  4GA3 A;  3SDU A;  2AZK A;  4P0X A;  2EWG A;  3KRF A;  4JVJ F;  4KVI A;  3ZCD A;  3ICZ A;  4NKF A;  3BNX A;  4KQS A;  4LA5 A;  3P5R A;  1YJ4 A;  2PS4 A;  4E9U A;  5E8H A;  2J1O A;  5JV2 F;  3TFN A;  5DZ2 A;  2Z4W A;  3BNY A;  5IKA A;  4NFK F;  3OYR A;  3AE0 A;  5ERM A;  3WJN A;  4LOB A;  2E92 A;  5KSX F;  4MC0 A;  2AEL A;  5HNA A;  2Q58 A;  2DH4 A;  3N5H F;  4DWG A;  1V4H A;  5ILD A;  5DJP F;  3WCD A;  4KFA A;  3VJC A;  4DZW A;  4K10 A;  3ACW A;  4MC3 A;  4P0W A;  5B0M A;  3WCC A;  1N22 A;  3AQC B;  1WMW A;  1DGP A;  3ASX A;  2Z52 A;  3VJ8 A;  1YYS A;  3N49 F;  4KVY A;  2AZJ A;  5ILY A;  4FJQ A;  3LOM A;  3VJ9 A;  5AYP A;  1V4I A;  1VG2 A;  3WCB A;  3LZ9 A;  1KIY A;  3WCH A;  3WEG A;  5IL3 A;  3QKC A;  4OMH A;  3WEK A;  4RXA A;  2F8C F;  4EA0 A;  2Q9Y A;  3RYE A;  5DJR F;  1VG4 A;  2F8Z F;  3DYF A;  1HXA A;  1WL3 A;  1YYQ A;  3ICN A;  3AQB B;  3PH7 A;  5I1U A;  1HM4 A;  3TFV A;  3OAC B;  2E8W A;  4H5C F;  4N9U A;  4P0V A;  4LTZ A;  4KUX A;  4KWD A;  4WK5 A;  5AFX A;  3DYH A;  3WCF A;  3OAB A;  2AZL A;  3WSA A;  3P8L A;  1PS1 A;  3SDR A;  3SAE A;  3KRC A;  1JFA A;  3SDV A;  2PS6 A;  5IK6 A;  5B0L A;  3TS7 A;  1UBW A;  2OGD A;  2Z7I A;  3M01 A;  3WCL A;  1FPS A;  4JXN A;  2O1O A;  3S9V A;  1VG7 A;  5IK0 A;  2Q80 A;  4NG6 A;  5IL8 A;  2ONH A;  1HXC A;  4QXS F;  3LGZ B;  3NF2 A;  4RXC A;  2ONG A;  3ZMB A;  3KRP B;  4JXY A;  2E8T A;  3WEJ A;  5EAS A;  1YHL A;  4LZ0 A;  3P5P A;  2E94 A;  5JA0 F;  3LK5 A;  3N6K F;  1V4K A;  5C05 A;  2E91 A;  1N24 A;  2QIS A;  3UCA A;  3EZ3 A;  4LFV F;  1UBX A;  2F94 F;  4DXJ A;  4F62 A;  3ADZ A;  5ERN A;  4LLT A;  3KRP A;  2Z4X A;  5DJV F;  5E8K A;  4L2X F;  3IBA A;  3Q1O A;  3KRO B;  3Q2Z A;  3W7F A;  4H5E F;  3N0G A;  4XQS F;  4NKE A;  3ICM A;  4LFG A;  3MZV A;  3ACX A;  3V66 A;  1YQ7 A;  3CP6 A;  3S4J A;  1WKZ A;  3LEE A;  4KQ5 A;  2H8O A;  2J1P A;  3KRO A;  2PS8 A;  3B7L A;  5B01 A;  3WEF A;  1YYR A;  2AET A;  2E4O A;  4KKM A;  1ZW5 A;  5ER8 A;  4LZC A;  3QQV A;  3LVS A;  2Z50 A;  4E9Z A;  1WL2 A;  5IMP A;  2E8U A;  1N20 A;  2P1C A;  4JYX A;  5HN8 A;  4NFI F;  3N46 F;  4HD1 A;  1YHK A;  2Z7H A;  3RMG A;  5JV0 F;  3N3D A;  5ILK A;  4GP2 A;  1V4E A;  2ZCR A;  1RQI A;  5B0I A;  3RYW A;  3NPR A;  3V1V A;  3ZL6 A;  5CG5 A;  4ZQ8 A;  3ICK A;  2E95 A;  2Z4Y A;  4JZB A;  2E8X A;  3WE9 A;  2PS5 A;  4DI5 A;  4F6V A;  5B0K A;  3KRA B;  4LPH F;  3DYG A;  3M9U A;  2ZEV A;  3WCE A;  4DWB A;  3OAC A;  1N1Z A;  5A0K A;  3LJI A;  2ZCO A;  4GAX A;  5HN7 A;  1N1B A;  4UMJ A;  3WCM A;  2E90 A;  4KVD A;  3N45 F;  5B0J A;  3V1X A;  3KRA A;  3LLW A;  1HM7 A;  3N1V F;  3LDW A;  3LSN A;  1YV5 A;  1V4J A;  5B00 A;  1N21 A;  4MC8 A;  2Z4V A;  3ZOU A;  5E8L A;  3LG5 A;  3CKE A;  3P8R A;  2ZCS A;  4LZ3 A;  5ILJ A;  3WCJ A;  3WCA A;  5A0J A;  4OKZ A;  3LGK A;  5DHK A;  5EAU A;  3CC9 A;  4LPG F;  3KRF B;  1WY0 A;  4DEM F;  1DI1 A;  2Z4Z A;  1HXG A;  4LXW A;  3WSB A;  4EA1 A;  3SDQ A;  2ZY1 A;  3G4F A;  4PVY F;  3WJK A;  3M0G A;  2FTZ A;  2E93 A;  5DIQ F;  5IVG A;  2F92 F;  5HN9 A;  4EA2 A;  2ZCQ A;  2OPN A;  3G4D A;  1WL1 A;  4OMG A;  1WL0 A;  4JZX A;  3NPK A;  2RAH A;  3VJD A;  5B03 A;  5ILI A;  5A0I A;  4OKM A;  5H9D A;  4RXD A;  5AEL A;  4XQT F;  4OGU A;  1YHM A;  4QPF A;  5CG6 A;  2J5C A;  3M02 A;  4LUU A;  1VG3 A;  3WEH A;  3Q2Q A;  4NUA A;  1EZF A;  5ERO A;  4LFE A;  4H5D F;  3PDE A;  4LTV A;  1YYU A;  2Z78 A;  4NFJ F;  5IM1 A;  3KBK A;  3PYB A;  5ILZ A;  3N1W F;  1UBV A;  3ZMC A;  2I19 A;  5IMI A;  3EFQ A;  4N1Z F;  5DGM F;  3OAB B;  4LIX A;  2E8V A;  1YYT A;  3WEI A;  2VF6 A;  3SDT A;  3KB9 A;  4KPJ A;  3NRI A;  3KRC B;  3RBM A;  5IKH A;  3N5J F;  4GP1 A;  3WCI A;  3M00 A;  5IMN A;  3WC9 A;  4FP4 A;  3WCG A;  4KVW A;  4RNQ A;  5ILH A;  4Q23 A;  3N0F A;  4RYP A;  3PKO A; 
#chains in the Genus database with same CATH topology
 5DGN F;  5AHU B;  1UBY A;  5DHI A;  2AEK A;  3APZ A;  4KPD A;  3TFP A;  4F6X A;  2F7M F;  3Q30 A;  2FOR A;  3VJE A;  2F89 F;  4RXE A;  4LA6 A;  3VJA A;  5IN8 A;  5EAT A;  4E1E A;  3N3L F;  3MAV A;  3AQ0 A;  3IPI A;  4PVX F;  4DHD A;  3LMD A;  1KIZ A;  3VJB A;  2OPM A;  3PYA A;  5JV1 F;  5IK9 A;  5B02 A;  4XQR F;  5JUZ F;  4KK2 A;  5DGS F;  3WJO A;  1N23 A;  1VG6 A;  3ACY A;  3EGT A;  2OA6 A;  2F9K F;  4LLS A;  2ZEU A;  1RTR A;  3P41 A;  3TC1 A;  1HX9 A;  4KQU A;  1JFG A;  5DW7 A;  1RQJ A;  2Q9Z A;  3ID0 A;  2PS7 A;  4GA3 A;  3SDU A;  2AZK A;  4P0X A;  2EWG A;  3KRF A;  4JVJ F;  4KVI A;  3ZCD A;  3ICZ A;  4NKF A;  3BNX A;  4KQS A;  4LA5 A;  3P5R A;  1YJ4 A;  2PS4 A;  4E9U A;  5E8H A;  2J1O A;  5JV2 F;  3TFN A;  5DZ2 A;  2Z4W A;  3BNY A;  5IKA A;  4NFK F;  3OYR A;  3AE0 A;  5ERM A;  3WJN A;  4LOB A;  2E92 A;  5KSX F;  4MC0 A;  2AEL A;  5HNA A;  2Q58 A;  2DH4 A;  3N5H F;  4DWG A;  1V4H A;  5ILD A;  5DJP F;  3WCD A;  4KFA A;  3VJC A;  4DZW A;  4K10 A;  3ACW A;  4MC3 A;  4P0W A;  5B0M A;  3WCC A;  1N22 A;  3AQC B;  1WMW A;  1DGP A;  3ASX A;  2Z52 A;  3VJ8 A;  1YYS A;  3N49 F;  4KVY A;  2AZJ A;  5ILY A;  4FJQ A;  3LOM A;  3VJ9 A;  5AYP A;  1V4I A;  1VG2 A;  3WCB A;  3LZ9 A;  1KIY A;  3WCH A;  3WEG A;  5IL3 A;  3QKC A;  4OMH A;  3WEK A;  4RXA A;  2F8C F;  4EA0 A;  2Q9Y A;  3RYE A;  5DJR F;  1VG4 A;  2F8Z F;  3DYF A;  1HXA A;  1WL3 A;  1YYQ A;  3ICN A;  3AQB B;  3PH7 A;  5I1U A;  1HM4 A;  3TFV A;  3OAC B;  2E8W A;  4H5C F;  4N9U A;  4P0V A;  4LTZ A;  4KUX A;  4KWD A;  4WK5 A;  5AFX A;  3DYH A;  3WCF A;  3OAB A;  2AZL A;  3WSA A;  3P8L A;  1PS1 A;  3SDR A;  3SAE A;  3KRC A;  1JFA A;  3SDV A;  2PS6 A;  5IK6 A;  5B0L A;  3TS7 A;  1UBW A;  2OGD A;  2Z7I A;  3M01 A;  3WCL A;  1FPS A;  4JXN A;  2O1O A;  3S9V A;  1VG7 A;  5IK0 A;  2Q80 A;  4NG6 A;  5IL8 A;  2ONH A;  1HXC A;  4QXS F;  3LGZ B;  3NF2 A;  4RXC A;  2ONG A;  3ZMB A;  3KRP B;  4JXY A;  2E8T A;  3WEJ A;  5EAS A;  1YHL A;  4LZ0 A;  3P5P A;  2E94 A;  5JA0 F;  3LK5 A;  3N6K F;  1V4K A;  5C05 A;  2E91 A;  1N24 A;  2QIS A;  3UCA A;  3EZ3 A;  4LFV F;  1UBX A;  2F94 F;  4DXJ A;  4F62 A;  3ADZ A;  5ERN A;  4LLT A;  3KRP A;  2Z4X A;  5DJV F;  5E8K A;  4L2X F;  3IBA A;  3Q1O A;  3KRO B;  3Q2Z A;  3W7F A;  4H5E F;  3N0G A;  4XQS F;  4NKE A;  3ICM A;  4LFG A;  3MZV A;  3ACX A;  3V66 A;  1YQ7 A;  3CP6 A;  3S4J A;  1WKZ A;  3LEE A;  4KQ5 A;  2H8O A;  2J1P A;  3KRO A;  2PS8 A;  3B7L A;  5B01 A;  3WEF A;  1YYR A;  2AET A;  2E4O A;  4KKM A;  1ZW5 A;  5ER8 A;  4LZC A;  3QQV A;  3LVS A;  2Z50 A;  4E9Z A;  1WL2 A;  5IMP A;  2E8U A;  1N20 A;  2P1C A;  4JYX A;  5HN8 A;  4NFI F;  3N46 F;  4HD1 A;  1YHK A;  2Z7H A;  3RMG A;  5JV0 F;  3N3D A;  5ILK A;  4GP2 A;  1V4E A;  2ZCR A;  1RQI A;  5B0I A;  3RYW A;  3NPR A;  3V1V A;  3ZL6 A;  5CG5 A;  4ZQ8 A;  3ICK A;  2E95 A;  2Z4Y A;  4JZB A;  2E8X A;  3WE9 A;  2PS5 A;  4DI5 A;  4F6V A;  5B0K A;  3KRA B;  4LPH F;  3DYG A;  3M9U A;  2ZEV A;  3WCE A;  4DWB A;  3OAC A;  1N1Z A;  5A0K A;  3LJI A;  2ZCO A;  4GAX A;  5HN7 A;  1N1B A;  4UMJ A;  3WCM A;  2E90 A;  4KVD A;  3N45 F;  5B0J A;  3V1X A;  3KRA A;  3LLW A;  1HM7 A;  3N1V F;  3LDW A;  3LSN A;  1YV5 A;  1V4J A;  5B00 A;  1N21 A;  4MC8 A;  2Z4V A;  3ZOU A;  5E8L A;  3LG5 A;  3CKE A;  3P8R A;  2ZCS A;  4LZ3 A;  5ILJ A;  3WCJ A;  3WCA A;  5A0J A;  4OKZ A;  3LGK A;  5DHK A;  5EAU A;  3CC9 A;  4LPG F;  3KRF B;  1WY0 A;  4DEM F;  1DI1 A;  2Z4Z A;  1HXG A;  4LXW A;  3WSB A;  4EA1 A;  3SDQ A;  2ZY1 A;  3G4F A;  4PVY F;  3WJK A;  3M0G A;  2FTZ A;  2E93 A;  5DIQ F;  5IVG A;  2F92 F;  5HN9 A;  4EA2 A;  2ZCQ A;  2OPN A;  3G4D A;  1WL1 A;  4OMG A;  1WL0 A;  4JZX A;  3NPK A;  2RAH A;  3VJD A;  5B03 A;  5ILI A;  5A0I A;  4OKM A;  5H9D A;  4RXD A;  5AEL A;  4XQT F;  4OGU A;  1YHM A;  4QPF A;  5CG6 A;  2J5C A;  3M02 A;  4LUU A;  1VG3 A;  3WEH A;  3Q2Q A;  4NUA A;  1EZF A;  5ERO A;  4LFE A;  4H5D F;  3PDE A;  4LTV A;  1YYU A;  2Z78 A;  4NFJ F;  5IM1 A;  3KBK A;  3PYB A;  5ILZ A;  3N1W F;  1UBV A;  3ZMC A;  2I19 A;  5IMI A;  3EFQ A;  4N1Z F;  5DGM F;  3OAB B;  4LIX A;  2E8V A;  1YYT A;  3WEI A;  2VF6 A;  3SDT A;  3KB9 A;  4KPJ A;  3NRI A;  3KRC B;  3RBM A;  5IKH A;  3N5J F;  4GP1 A;  3WCI A;  3M00 A;  5IMN A;  3WC9 A;  4FP4 A;  3WCG A;  4KVW A;  4RNQ A;  5ILH A;  4Q23 A;  3N0F A;  4RYP A;  3PKO A; 
#chains in the Genus database with same CATH homology
 5DGN F;  5AHU B;  1UBY A;  5DHI A;  2AEK A;  3APZ A;  4KPD A;  3TFP A;  4F6X A;  2F7M F;  3Q30 A;  2FOR A;  3VJE A;  2F89 F;  4RXE A;  4LA6 A;  3VJA A;  5IN8 A;  5EAT A;  4E1E A;  3N3L F;  3MAV A;  3AQ0 A;  3IPI A;  4PVX F;  4DHD A;  3LMD A;  1KIZ A;  3VJB A;  2OPM A;  3PYA A;  5JV1 F;  5IK9 A;  5B02 A;  4XQR F;  5JUZ F;  4KK2 A;  5DGS F;  3WJO A;  1N23 A;  1VG6 A;  3ACY A;  3EGT A;  2OA6 A;  2F9K F;  4LLS A;  2ZEU A;  1RTR A;  3P41 A;  3TC1 A;  1HX9 A;  4KQU A;  1JFG A;  5DW7 A;  1RQJ A;  2Q9Z A;  3ID0 A;  2PS7 A;  4GA3 A;  3SDU A;  2AZK A;  4P0X A;  2EWG A;  3KRF A;  4JVJ F;  4KVI A;  3ZCD A;  3ICZ A;  4NKF A;  3BNX A;  4KQS A;  4LA5 A;  3P5R A;  1YJ4 A;  2PS4 A;  4E9U A;  5E8H A;  2J1O A;  5JV2 F;  3TFN A;  5DZ2 A;  2Z4W A;  3BNY A;  5IKA A;  4NFK F;  3OYR A;  3AE0 A;  5ERM A;  3WJN A;  4LOB A;  2E92 A;  5KSX F;  4MC0 A;  2AEL A;  5HNA A;  2Q58 A;  2DH4 A;  3N5H F;  4DWG A;  1V4H A;  5ILD A;  5DJP F;  3WCD A;  4KFA A;  3VJC A;  4DZW A;  4K10 A;  3ACW A;  4MC3 A;  4P0W A;  5B0M A;  3WCC A;  1N22 A;  3AQC B;  1WMW A;  1DGP A;  3ASX A;  2Z52 A;  3VJ8 A;  1YYS A;  3N49 F;  4KVY A;  2AZJ A;  5ILY A;  4FJQ A;  3LOM A;  3VJ9 A;  5AYP A;  1V4I A;  1VG2 A;  3WCB A;  3LZ9 A;  1KIY A;  3WCH A;  3WEG A;  5IL3 A;  3QKC A;  4OMH A;  3WEK A;  4RXA A;  2F8C F;  4EA0 A;  2Q9Y A;  3RYE A;  5DJR F;  1VG4 A;  2F8Z F;  3DYF A;  1HXA A;  1WL3 A;  1YYQ A;  3ICN A;  3AQB B;  3PH7 A;  5I1U A;  1HM4 A;  3TFV A;  3OAC B;  2E8W A;  4H5C F;  4N9U A;  4P0V A;  4LTZ A;  4KUX A;  4KWD A;  4WK5 A;  5AFX A;  3DYH A;  3WCF A;  3OAB A;  2AZL A;  3WSA A;  3P8L A;  1PS1 A;  3SDR A;  3SAE A;  3KRC A;  1JFA A;  3SDV A;  2PS6 A;  5IK6 A;  5B0L A;  3TS7 A;  1UBW A;  2OGD A;  2Z7I A;  3M01 A;  3WCL A;  1FPS A;  4JXN A;  2O1O A;  3S9V A;  1VG7 A;  5IK0 A;  2Q80 A;  4NG6 A;  5IL8 A;  2ONH A;  1HXC A;  4QXS F;  3LGZ B;  3NF2 A;  4RXC A;  2ONG A;  3ZMB A;  3KRP B;  4JXY A;  2E8T A;  3WEJ A;  5EAS A;  1YHL A;  4LZ0 A;  3P5P A;  2E94 A;  5JA0 F;  3LK5 A;  3N6K F;  1V4K A;  5C05 A;  2E91 A;  1N24 A;  2QIS A;  3UCA A;  3EZ3 A;  4LFV F;  1UBX A;  2F94 F;  4DXJ A;  4F62 A;  3ADZ A;  5ERN A;  4LLT A;  3KRP A;  2Z4X A;  5DJV F;  5E8K A;  4L2X F;  3IBA A;  3Q1O A;  3KRO B;  3Q2Z A;  3W7F A;  4H5E F;  3N0G A;  4XQS F;  4NKE A;  3ICM A;  4LFG A;  3MZV A;  3ACX A;  3V66 A;  1YQ7 A;  3CP6 A;  3S4J A;  1WKZ A;  3LEE A;  4KQ5 A;  2H8O A;  2J1P A;  3KRO A;  2PS8 A;  3B7L A;  5B01 A;  3WEF A;  1YYR A;  2AET A;  2E4O A;  4KKM A;  1ZW5 A;  5ER8 A;  4LZC A;  3QQV A;  3LVS A;  2Z50 A;  4E9Z A;  1WL2 A;  5IMP A;  2E8U A;  1N20 A;  2P1C A;  4JYX A;  5HN8 A;  4NFI F;  3N46 F;  4HD1 A;  1YHK A;  2Z7H A;  3RMG A;  5JV0 F;  3N3D A;  5ILK A;  4GP2 A;  1V4E A;  2ZCR A;  1RQI A;  5B0I A;  3RYW A;  3NPR A;  3V1V A;  3ZL6 A;  5CG5 A;  4ZQ8 A;  3ICK A;  2E95 A;  2Z4Y A;  4JZB A;  2E8X A;  3WE9 A;  2PS5 A;  4DI5 A;  4F6V A;  5B0K A;  3KRA B;  4LPH F;  3DYG A;  3M9U A;  2ZEV A;  3WCE A;  4DWB A;  3OAC A;  1N1Z A;  5A0K A;  3LJI A;  2ZCO A;  4GAX A;  5HN7 A;  1N1B A;  4UMJ A;  3WCM A;  2E90 A;  4KVD A;  3N45 F;  5B0J A;  3V1X A;  3KRA A;  3LLW A;  1HM7 A;  3N1V F;  3LDW A;  3LSN A;  1YV5 A;  1V4J A;  5B00 A;  1N21 A;  4MC8 A;  2Z4V A;  3ZOU A;  5E8L A;  3LG5 A;  3CKE A;  3P8R A;  2ZCS A;  4LZ3 A;  5ILJ A;  3WCJ A;  3WCA A;  5A0J A;  4OKZ A;  3LGK A;  5DHK A;  5EAU A;  3CC9 A;  4LPG F;  3KRF B;  1WY0 A;  4DEM F;  1DI1 A;  2Z4Z A;  1HXG A;  4LXW A;  3WSB A;  4EA1 A;  3SDQ A;  2ZY1 A;  3G4F A;  4PVY F;  3WJK A;  3M0G A;  2FTZ A;  2E93 A;  5DIQ F;  5IVG A;  2F92 F;  5HN9 A;  4EA2 A;  2ZCQ A;  2OPN A;  3G4D A;  1WL1 A;  4OMG A;  1WL0 A;  4JZX A;  3NPK A;  2RAH A;  3VJD A;  5B03 A;  5ILI A;  5A0I A;  4OKM A;  5H9D A;  4RXD A;  5AEL A;  4XQT F;  4OGU A;  1YHM A;  4QPF A;  5CG6 A;  2J5C A;  3M02 A;  4LUU A;  1VG3 A;  3WEH A;  3Q2Q A;  4NUA A;  1EZF A;  5ERO A;  4LFE A;  4H5D F;  3PDE A;  4LTV A;  1YYU A;  2Z78 A;  4NFJ F;  5IM1 A;  3KBK A;  3PYB A;  5ILZ A;  3N1W F;  1UBV A;  3ZMC A;  2I19 A;  5IMI A;  3EFQ A;  4N1Z F;  5DGM F;  3OAB B;  4LIX A;  2E8V A;  1YYT A;  3WEI A;  2VF6 A;  3SDT A;  3KB9 A;  4KPJ A;  3NRI A;  3KRC B;  3RBM A;  5IKH A;  3N5J F;  4GP1 A;  3WCI A;  3M00 A;  5IMN A;  3WC9 A;  4FP4 A;  3WCG A;  4KVW A;  4RNQ A;  5ILH A;  4Q23 A;  3N0F A;  4RYP A;  3PKO A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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