4JVJF

Crystal structure of human fpps in complex with magnesium, cl01131, and sulfate
Total Genus 130
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
130
sequence length
343
structure length
343
Chain Sequence
DVYAQEKQDFVQHFSQIVRVLTEDEMGHPEIGDAIARLKEVLEYNAIGGKYNRGLTVVVAFRELVEPRKQDADSLQRAWTVGWCVELLQAFFLVADDIMDSSLTRRGQICWYQKPGVGLDAINDANLLEACIYRLLKLYCREQPYYLNLIELFLQSSYQTEIGQTLDLLTAPQGNVDLVRFTEKRYKSIVKYKTAFYSFYLPIAAAMYMAGIDGEKEHANAKKILLEMGEFFQIQDDYLDLFGDPSVTGKIGTDIQDNKCSWLVVQCLQRATPEQYQILKENYGQKEAEKVARVKALYEELDLPAVFLQYEEDSYSHIMALIEQYAAPLPPAVFLGLARKIYK
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Transferase/transferase inhibitor
source organism Homo sapiens
publication title Thienopyrimidine Bisphosphonate (ThPBP) Inhibitors of the Human Farnesyl Pyrophosphate Synthase: Optimization and Characterization of the Mode of Inhibition.
pubmed doi rcsb
molecule keywords Farnesyl pyrophosphate synthase
total genus 130
structure length 343
sequence length 343
ec nomenclature ec 2.5.1.1: Dimethylallyltranstransferase.
pdb deposition date 2013-03-25

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
F PF00348 polyprenyl_synt Polyprenyl synthetase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.600.10 Mainly Alpha Orthogonal Bundle Farnesyl Diphosphate Synthase Farnesyl Diphosphate Synthase 4jvjF00
5IK9A 3OABB 1UBXA 3WCJA 1PS1A 1RTRA 1HXAA 5IKHA 1JFGA 3S9VA 4LTZA 3WCLA 3DYGA 2J1PA 4Q23A 3WEFA 2E8XA 3B7LA 4LOBA 3ASXA 3V1VA 5HN9A 5ILHA 3MAVA 3LMDA 4KVDA 3KBKA 3KRFB 3WEJA 2FORA 2I19A 4XQTF 3WCMA 3WC9A 3AQCB 3OYRA 1YYQA 3NF2A 4LFVF 3P8RA 5JV1F 4GA3A 3N5JF 3ICNA 5AHUB 2OA6A 4LTVA 3ADZA 5HN8A 3AQ0A 1V4EA 4F62A 5IM1A 3AQBB 5ER8A 3KROB 3LSNA 4JZBA 3WEHA 5E8LA 2AETA 5ERMA 2E93A 5AFXA 2ZEUA 4KUXA 1YJ4A 1VG6A 3VJEA 1UBVA 4KK2A 5DJRF 3TFVA 2RAHA 3OABA 3WE9A 4HD1A 4KQSA 1YHLA 3DYFA 3Q2ZA 3RYEA 5B0LA 3SAEA 3N49F 5C05A 5H9DA 1KIZA 3EFQA 1N24A 3WEGA 4H5EF 4NUAA 3M02A 2F7MF 4DWBA 5E8HA 5AELA 4JVJF 2OGDA 5A0JA 4RYPA 3SDRA 3AE0A 4LIXA 3BNYA 3PH7A 4LLSA 5I1UA 5B00A 4PVYF 3NPKA 4OKMA 2Z4VA 2DH4A 5IMIA 3V66A 5DHKA 4MC3A 4WK5A 3SDVA 3NPRA 3M9UA 2Z78A 4PVXF 2F9KF 1YYUA 5A0KA 5DIQF 3KROA 1RQJA 3N3LF 3ACXA 5DGSF 4NKEA 2ONGA 4MC0A 3VJDA 3N1WF 3APZA 4P0XA 5A0IA 2QISA 4FJQA 2F92F 2PS6A 4KKMA 4E9UA 2Z4WA 3CP6A 4UMJA 2ZCOA 4JZXA 3KRPB 1RQIA 3KRCB 3P5PA 5IMPA 5IK6A 2ZCSA 5B02A 3ICMA 3CKEA 3QKCA 3VJAA 4QPFA 3WCEA 3WEIA 4LZ3A 3ICKA 3N46F 3VJCA 2Z4XA 5IL3A 3LJIA 3IBAA 3N0GA 4KQ5A 5AYPA 1N21A 3G4FA 4QXSF 4LFEA 4LA6A 3DYHA 5EATA 2PS8A 3N45F 4EA1A 3TFNA 4KVYA 2E4OA 4KPDA 4DEMF 4GP2A 4OMGA 3OACA 5DJPF 3Q30A 1WL2A 3M01A 4F6VA 3N1VF 3S4JA 2FTZA 1VG3A 3P41A 2Z4YA 1VG7A 1YHMA 2J5CA 2PS5A 3LOMA 3LEEA 2F94F 3WJNA 4KFAA 3VJ9A 1V4HA 4JYXA 3LLWA 1HM4A 5EAUA 1N20A 2ONHA 3ZCDA 5CG5A 2AZJA 4KWDA 1HX9A 3KRPA 3ZL6A 3KRCA 4DWGA 3M0GA 2E90A 5IKAA 2F89F 3KRAB 4KQUA 3RBMA 1WL0A 4RXAA 1N23A 4NG6A 5HNAA 2PS7A 4ZQ8A 3EGTA 1YYSA 4FP4A 4GAXA 1UBYA 3KRFA 2ZCQA 4RXCA 3WCBA 5B0JA 3WSAA 5IL8A 3LVSA 5E8KA 5ILYA 1N1ZA 5IK0A 1N1BA 3SDUA 5B01A 2E8VA 3WSBA 2AELA 4XQRF 3ZMBA 2OPMA 4LA5A 4NFJF 2AEKA 3V1XA 3WJKA 3WCDA 3MZVA 1WY0A 5ILDA 5CG6A 5ILIA 3VJBA 2F8ZF 1WKZA 4F6XA 5JV0F 5DGNF 4P0WA 4E1EA 3N0FA 2Z4ZA 5EASA 5B03A 4DXJA 2Z50A 2ZEVA 1N22A 4EA0A 4LZ0A 5IVGA 3PYAA 2Q9YA 2E8UA 3PDEA 5ILJA 3BNXA 3WCHA 3ZMCA 1WL3A 4H5CF 2E8TA 1EZFA 3LDWA 4DI5A 2OPNA 1V4KA 3KRAA 3LZ9A 3P8LA 1V4JA 3N6KF 2E92A 3RMGA 4RNQA 2Q58A 4LUUA 2AZLA 3ACYA 5ILZA 3ACWA 4LPHF 5JUZF 4XQSF 5EROA 3VJ8A 1DI1A 3QQVA 3P5RA 1VG2A 1DGPA 5DGMF 4RXDA 1YHKA 1HXGA 2ZY1A 4N9UA 3Q1OA 3IPIA 3EZ3A 4DZWA 2J1OA 3LK5A 5DHIA 3SDQA 3WJOA 4RXEA 2AZKA 5HN7A 3G4DA 3WCFA 4L2XF 5KSXF 1YYTA 4NFKF 4JXNA 3LGKA 5JA0F 5B0IA 2Q80A 4K10A 3WCGA 4OMHA 1YYRA 4P0VA 4NFIF 1KIYA 1YV5A 4OGUA 4GP1A 3M00A 3ZOUA 3WCIA 1HM7A 2E95A 3TFPA 4KPJA 4MC8A 4DHDA 5DZ2A 1WL1A 4E9ZA 2PS4A 4N1ZF 4NKFA 5B0KA 3CC9A 3NRIA 2EWGA 1YQ7A 3N5HF 4LPGF 1UBWA 4OKZA 3Q2QA 3LGZB 3UCAA 1HXCA 5IMNA 1JFAA 3TS7A 5IN8A 2P1CA 3WCCA 2Z7IA 2E94A 2F8CF 1ZW5A 3RYWA 2Q9ZA 1WMWA 4EA2A 4LXWA 3N3DA 2Z7HA 5JV2F 2E91A 3LG5A 1V4IA 4LZCA 1VG4A 3ICZA 1FPSA 3TC1A 2VF6A 4H5DF 2Z52A 4LLTA 2E8WA 3OACB 5ILKA 2O1OA 3W7FA 3KB9A 5ERNA 3PKOA 2H8OA 3SDTA 2ZCRA 5B0MA 4JXYA 5DJVF 3WEKA 4KVIA 4KVWA 5DW7A 4LFGA 3WCAA 3PYBA 3ID0A
chains in the Genus database with same CATH superfamily
5IK9A 3OABB 1UBXA 3WCJA 1PS1A 1RTRA 1HXAA 5IKHA 1JFGA 3S9VA 4LTZA 3WCLA 3DYGA 2J1PA 4Q23A 3WEFA 2E8XA 3B7LA 4LOBA 3ASXA 3V1VA 5HN9A 5ILHA 3MAVA 3LMDA 4KVDA 3KBKA 3KRFB 3WEJA 2FORA 2I19A 4XQTF 3WCMA 3WC9A 3AQCB 3OYRA 1YYQA 3NF2A 4LFVF 3P8RA 5JV1F 4GA3A 3N5JF 3ICNA 5AHUB 2OA6A 4LTVA 3ADZA 5HN8A 3AQ0A 1V4EA 4F62A 5IM1A 3AQBB 5ER8A 3KROB 3LSNA 4JZBA 3WEHA 5E8LA 2AETA 5ERMA 2E93A 5AFXA 2ZEUA 4KUXA 1YJ4A 1VG6A 3VJEA 1UBVA 4KK2A 5DJRF 3TFVA 2RAHA 3OABA 3WE9A 4HD1A 4KQSA 1YHLA 3DYFA 3Q2ZA 3RYEA 5B0LA 3SAEA 3N49F 5C05A 5H9DA 1KIZA 3EFQA 1N24A 3WEGA 4H5EF 4NUAA 3M02A 2F7MF 4DWBA 5E8HA 5AELA 4JVJF 2OGDA 5A0JA 4RYPA 3SDRA 3AE0A 4LIXA 3BNYA 3PH7A 4LLSA 5I1UA 5B00A 4PVYF 3NPKA 4OKMA 2Z4VA 2DH4A 5IMIA 3V66A 5DHKA 4MC3A 4WK5A 3SDVA 3NPRA 3M9UA 2Z78A 4PVXF 2F9KF 1YYUA 5A0KA 5DIQF 3KROA 1RQJA 3N3LF 3ACXA 5DGSF 4NKEA 2ONGA 4MC0A 3VJDA 3N1WF 3APZA 4P0XA 5A0IA 2QISA 4FJQA 2F92F 2PS6A 4KKMA 4E9UA 2Z4WA 3CP6A 4UMJA 2ZCOA 4JZXA 3KRPB 1RQIA 3KRCB 3P5PA 5IMPA 5IK6A 2ZCSA 5B02A 3ICMA 3CKEA 3QKCA 3VJAA 4QPFA 3WCEA 3WEIA 4LZ3A 3ICKA 3N46F 3VJCA 2Z4XA 5IL3A 3LJIA 3IBAA 3N0GA 4KQ5A 5AYPA 1N21A 3G4FA 4QXSF 4LFEA 4LA6A 3DYHA 5EATA 2PS8A 3N45F 4EA1A 3TFNA 4KVYA 2E4OA 4KPDA 4DEMF 4GP2A 4OMGA 3OACA 5DJPF 3Q30A 1WL2A 3M01A 4F6VA 3N1VF 3S4JA 2FTZA 1VG3A 3P41A 2Z4YA 1VG7A 1YHMA 2J5CA 2PS5A 3LOMA 3LEEA 2F94F 3WJNA 4KFAA 3VJ9A 1V4HA 4JYXA 3LLWA 1HM4A 5EAUA 1N20A 2ONHA 3ZCDA 5CG5A 2AZJA 4KWDA 1HX9A 3KRPA 3ZL6A 3KRCA 4DWGA 3M0GA 2E90A 5IKAA 2F89F 3KRAB 4KQUA 3RBMA 1WL0A 4RXAA 1N23A 4NG6A 5HNAA 2PS7A 4ZQ8A 3EGTA 1YYSA 4FP4A 4GAXA 1UBYA 3KRFA 2ZCQA 4RXCA 3WCBA 5B0JA 3WSAA 5IL8A 3LVSA 5E8KA 5ILYA 1N1ZA 5IK0A 1N1BA 3SDUA 5B01A 2E8VA 3WSBA 2AELA 4XQRF 3ZMBA 2OPMA 4LA5A 4NFJF 2AEKA 3V1XA 3WJKA 3WCDA 3MZVA 1WY0A 5ILDA 5CG6A 5ILIA 3VJBA 2F8ZF 1WKZA 4F6XA 5JV0F 5DGNF 4P0WA 4E1EA 3N0FA 2Z4ZA 5EASA 5B03A 4DXJA 2Z50A 2ZEVA 1N22A 4EA0A 4LZ0A 5IVGA 3PYAA 2Q9YA 2E8UA 3PDEA 5ILJA 3BNXA 3WCHA 3ZMCA 1WL3A 4H5CF 2E8TA 1EZFA 3LDWA 4DI5A 2OPNA 1V4KA 3KRAA 3LZ9A 3P8LA 1V4JA 3N6KF 2E92A 3RMGA 4RNQA 2Q58A 4LUUA 2AZLA 3ACYA 5ILZA 3ACWA 4LPHF 5JUZF 4XQSF 5EROA 3VJ8A 1DI1A 3QQVA 3P5RA 1VG2A 1DGPA 5DGMF 4RXDA 1YHKA 1HXGA 2ZY1A 4N9UA 3Q1OA 3IPIA 3EZ3A 4DZWA 2J1OA 3LK5A 5DHIA 3SDQA 3WJOA 4RXEA 2AZKA 5HN7A 3G4DA 3WCFA 4L2XF 5KSXF 1YYTA 4NFKF 4JXNA 3LGKA 5JA0F 5B0IA 2Q80A 4K10A 3WCGA 4OMHA 1YYRA 4P0VA 4NFIF 1KIYA 1YV5A 4OGUA 4GP1A 3M00A 3ZOUA 3WCIA 1HM7A 2E95A 3TFPA 4KPJA 4MC8A 4DHDA 5DZ2A 1WL1A 4E9ZA 2PS4A 4N1ZF 4NKFA 5B0KA 3CC9A 3NRIA 2EWGA 1YQ7A 3N5HF 4LPGF 1UBWA 4OKZA 3Q2QA 3LGZB 3UCAA 1HXCA 5IMNA 1JFAA 3TS7A 5IN8A 2P1CA 3WCCA 2Z7IA 2E94A 2F8CF 1ZW5A 3RYWA 2Q9ZA 1WMWA 4EA2A 4LXWA 3N3DA 2Z7HA 5JV2F 2E91A 3LG5A 1V4IA 4LZCA 1VG4A 3ICZA 1FPSA 3TC1A 2VF6A 4H5DF 2Z52A 4LLTA 2E8WA 3OACB 5ILKA 2O1OA 3W7FA 3KB9A 5ERNA 3PKOA 2H8OA 3SDTA 2ZCRA 5B0MA 4JXYA 5DJVF 3WEKA 4KVIA 4KVWA 5DW7A 4LFGA 3WCAA 3PYBA 3ID0A
chains in the Genus database with same CATH topology
5IK9A 3OABB 1UBXA 3WCJA 1PS1A 1RTRA 1HXAA 5IKHA 1JFGA 3S9VA 4LTZA 3WCLA 3DYGA 2J1PA 4Q23A 3WEFA 2E8XA 3B7LA 4LOBA 3ASXA 3V1VA 5HN9A 5ILHA 3MAVA 3LMDA 4KVDA 3KBKA 3KRFB 3WEJA 2FORA 2I19A 4XQTF 3WCMA 3WC9A 3AQCB 3OYRA 1YYQA 3NF2A 4LFVF 3P8RA 5JV1F 4GA3A 3N5JF 3ICNA 5AHUB 2OA6A 4LTVA 3ADZA 5HN8A 3AQ0A 1V4EA 4F62A 5IM1A 3AQBB 5ER8A 3KROB 3LSNA 4JZBA 3WEHA 5E8LA 2AETA 5ERMA 2E93A 5AFXA 2ZEUA 4KUXA 1YJ4A 1VG6A 3VJEA 1UBVA 4KK2A 5DJRF 3TFVA 2RAHA 3OABA 3WE9A 4HD1A 4KQSA 1YHLA 3DYFA 3Q2ZA 3RYEA 5B0LA 3SAEA 3N49F 5C05A 5H9DA 1KIZA 3EFQA 1N24A 3WEGA 4H5EF 4NUAA 3M02A 2F7MF 4DWBA 5E8HA 5AELA 4JVJF 2OGDA 5A0JA 4RYPA 3SDRA 3AE0A 4LIXA 3BNYA 3PH7A 4LLSA 5I1UA 5B00A 4PVYF 3NPKA 4OKMA 2Z4VA 2DH4A 5IMIA 3V66A 5DHKA 4MC3A 4WK5A 3SDVA 3NPRA 3M9UA 2Z78A 4PVXF 2F9KF 1YYUA 5A0KA 5DIQF 3KROA 1RQJA 3N3LF 3ACXA 5DGSF 4NKEA 2ONGA 4MC0A 3VJDA 3N1WF 3APZA 4P0XA 5A0IA 2QISA 4FJQA 2F92F 2PS6A 4KKMA 4E9UA 2Z4WA 3CP6A 4UMJA 2ZCOA 4JZXA 3KRPB 1RQIA 3KRCB 3P5PA 5IMPA 5IK6A 2ZCSA 5B02A 3ICMA 3CKEA 3QKCA 3VJAA 4QPFA 3WCEA 3WEIA 4LZ3A 3ICKA 3N46F 3VJCA 2Z4XA 5IL3A 3LJIA 3IBAA 3N0GA 4KQ5A 5AYPA 1N21A 3G4FA 4QXSF 4LFEA 4LA6A 3DYHA 5EATA 2PS8A 3N45F 4EA1A 3TFNA 4KVYA 2E4OA 4KPDA 4DEMF 4GP2A 4OMGA 3OACA 5DJPF 3Q30A 1WL2A 3M01A 4F6VA 3N1VF 3S4JA 2FTZA 1VG3A 3P41A 2Z4YA 1VG7A 1YHMA 2J5CA 2PS5A 3LOMA 3LEEA 2F94F 3WJNA 4KFAA 3VJ9A 1V4HA 4JYXA 3LLWA 1HM4A 5EAUA 1N20A 2ONHA 3ZCDA 5CG5A 2AZJA 4KWDA 1HX9A 3KRPA 3ZL6A 3KRCA 4DWGA 3M0GA 2E90A 5IKAA 2F89F 3KRAB 4KQUA 3RBMA 1WL0A 4RXAA 1N23A 4NG6A 5HNAA 2PS7A 4ZQ8A 3EGTA 1YYSA 4FP4A 4GAXA 1UBYA 3KRFA 2ZCQA 4RXCA 3WCBA 5B0JA 3WSAA 5IL8A 3LVSA 5E8KA 5ILYA 1N1ZA 5IK0A 1N1BA 3SDUA 5B01A 2E8VA 3WSBA 2AELA 4XQRF 3ZMBA 2OPMA 4LA5A 4NFJF 2AEKA 3V1XA 3WJKA 3WCDA 3MZVA 1WY0A 5ILDA 5CG6A 5ILIA 3VJBA 2F8ZF 1WKZA 4F6XA 5JV0F 5DGNF 4P0WA 4E1EA 3N0FA 2Z4ZA 5EASA 5B03A 4DXJA 2Z50A 2ZEVA 1N22A 4EA0A 4LZ0A 5IVGA 3PYAA 2Q9YA 2E8UA 3PDEA 5ILJA 3BNXA 3WCHA 3ZMCA 1WL3A 4H5CF 2E8TA 1EZFA 3LDWA 4DI5A 2OPNA 1V4KA 3KRAA 3LZ9A 3P8LA 1V4JA 3N6KF 2E92A 3RMGA 4RNQA 2Q58A 4LUUA 2AZLA 3ACYA 5ILZA 3ACWA 4LPHF 5JUZF 4XQSF 5EROA 3VJ8A 1DI1A 3QQVA 3P5RA 1VG2A 1DGPA 5DGMF 4RXDA 1YHKA 1HXGA 2ZY1A 4N9UA 3Q1OA 3IPIA 3EZ3A 4DZWA 2J1OA 3LK5A 5DHIA 3SDQA 3WJOA 4RXEA 2AZKA 5HN7A 3G4DA 3WCFA 4L2XF 5KSXF 1YYTA 4NFKF 4JXNA 3LGKA 5JA0F 5B0IA 2Q80A 4K10A 3WCGA 4OMHA 1YYRA 4P0VA 4NFIF 1KIYA 1YV5A 4OGUA 4GP1A 3M00A 3ZOUA 3WCIA 1HM7A 2E95A 3TFPA 4KPJA 4MC8A 4DHDA 5DZ2A 1WL1A 4E9ZA 2PS4A 4N1ZF 4NKFA 5B0KA 3CC9A 3NRIA 2EWGA 1YQ7A 3N5HF 4LPGF 1UBWA 4OKZA 3Q2QA 3LGZB 3UCAA 1HXCA 5IMNA 1JFAA 3TS7A 5IN8A 2P1CA 3WCCA 2Z7IA 2E94A 2F8CF 1ZW5A 3RYWA 2Q9ZA 1WMWA 4EA2A 4LXWA 3N3DA 2Z7HA 5JV2F 2E91A 3LG5A 1V4IA 4LZCA 1VG4A 3ICZA 1FPSA 3TC1A 2VF6A 4H5DF 2Z52A 4LLTA 2E8WA 3OACB 5ILKA 2O1OA 3W7FA 3KB9A 5ERNA 3PKOA 2H8OA 3SDTA 2ZCRA 5B0MA 4JXYA 5DJVF 3WEKA 4KVIA 4KVWA 5DW7A 4LFGA 3WCAA 3PYBA 3ID0A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5IK9 A;  3OAB B;  1UBX A;  3WCJ A;  1PS1 A;  1RTR A;  1HXA A;  5IKH A;  1JFG A;  3S9V A;  4LTZ A;  3WCL A;  3DYG A;  2J1P A;  4Q23 A;  3WEF A;  2E8X A;  3B7L A;  4LOB A;  3ASX A;  3V1V A;  5HN9 A;  5ILH A;  3MAV A;  3LMD A;  4KVD A;  3KBK A;  3KRF B;  3WEJ A;  2FOR A;  2I19 A;  4XQT F;  3WCM A;  3WC9 A;  3AQC B;  3OYR A;  1YYQ A;  3NF2 A;  4LFV F;  3P8R A;  5JV1 F;  4GA3 A;  3N5J F;  3ICN A;  5AHU B;  2OA6 A;  4LTV A;  3ADZ A;  5HN8 A;  3AQ0 A;  1V4E A;  4F62 A;  5IM1 A;  3AQB B;  5ER8 A;  3KRO B;  3LSN A;  4JZB A;  3WEH A;  5E8L A;  2AET A;  5ERM A;  2E93 A;  5AFX A;  2ZEU A;  4KUX A;  1YJ4 A;  1VG6 A;  3VJE A;  1UBV A;  4KK2 A;  5DJR F;  3TFV A;  2RAH A;  3OAB A;  3WE9 A;  4HD1 A;  4KQS A;  1YHL A;  3DYF A;  3Q2Z A;  3RYE A;  5B0L A;  3SAE A;  3N49 F;  5C05 A;  5H9D A;  1KIZ A;  3EFQ A;  1N24 A;  3WEG A;  4H5E F;  4NUA A;  3M02 A;  2F7M F;  4DWB A;  5E8H A;  5AEL A;  4JVJ F;  2OGD A;  5A0J A;  4RYP A;  3SDR A;  3AE0 A;  4LIX A;  3BNY A;  3PH7 A;  4LLS A;  5I1U A;  5B00 A;  4PVY F;  3NPK A;  4OKM A;  2Z4V A;  2DH4 A;  5IMI A;  3V66 A;  5DHK A;  4MC3 A;  4WK5 A;  3SDV A;  3NPR A;  3M9U A;  2Z78 A;  4PVX F;  2F9K F;  1YYU A;  5A0K A;  5DIQ F;  3KRO A;  1RQJ A;  3N3L F;  3ACX A;  5DGS F;  4NKE A;  2ONG A;  4MC0 A;  3VJD A;  3N1W F;  3APZ A;  4P0X A;  5A0I A;  2QIS A;  4FJQ A;  2F92 F;  2PS6 A;  4KKM A;  4E9U A;  2Z4W A;  3CP6 A;  4UMJ A;  2ZCO A;  4JZX A;  3KRP B;  1RQI A;  3KRC B;  3P5P A;  5IMP A;  5IK6 A;  2ZCS A;  5B02 A;  3ICM A;  3CKE A;  3QKC A;  3VJA A;  4QPF A;  3WCE A;  3WEI A;  4LZ3 A;  3ICK A;  3N46 F;  3VJC A;  2Z4X A;  5IL3 A;  3LJI A;  3IBA A;  3N0G A;  4KQ5 A;  5AYP A;  1N21 A;  3G4F A;  4QXS F;  4LFE A;  4LA6 A;  3DYH A;  5EAT A;  2PS8 A;  3N45 F;  4EA1 A;  3TFN A;  4KVY A;  2E4O A;  4KPD A;  4DEM F;  4GP2 A;  4OMG A;  3OAC A;  5DJP F;  3Q30 A;  1WL2 A;  3M01 A;  4F6V A;  3N1V F;  3S4J A;  2FTZ A;  1VG3 A;  3P41 A;  2Z4Y A;  1VG7 A;  1YHM A;  2J5C A;  2PS5 A;  3LOM A;  3LEE A;  2F94 F;  3WJN A;  4KFA A;  3VJ9 A;  1V4H A;  4JYX A;  3LLW A;  1HM4 A;  5EAU A;  1N20 A;  2ONH A;  3ZCD A;  5CG5 A;  2AZJ A;  4KWD A;  1HX9 A;  3KRP A;  3ZL6 A;  3KRC A;  4DWG A;  3M0G A;  2E90 A;  5IKA A;  2F89 F;  3KRA B;  4KQU A;  3RBM A;  1WL0 A;  4RXA A;  1N23 A;  4NG6 A;  5HNA A;  2PS7 A;  4ZQ8 A;  3EGT A;  1YYS A;  4FP4 A;  4GAX A;  1UBY A;  3KRF A;  2ZCQ A;  4RXC A;  3WCB A;  5B0J A;  3WSA A;  5IL8 A;  3LVS A;  5E8K A;  5ILY A;  1N1Z A;  5IK0 A;  1N1B A;  3SDU A;  5B01 A;  2E8V A;  3WSB A;  2AEL A;  4XQR F;  3ZMB A;  2OPM A;  4LA5 A;  4NFJ F;  2AEK A;  3V1X A;  3WJK A;  3WCD A;  3MZV A;  1WY0 A;  5ILD A;  5CG6 A;  5ILI A;  3VJB A;  2F8Z F;  1WKZ A;  4F6X A;  5JV0 F;  5DGN F;  4P0W A;  4E1E A;  3N0F A;  2Z4Z A;  5EAS A;  5B03 A;  4DXJ A;  2Z50 A;  2ZEV A;  1N22 A;  4EA0 A;  4LZ0 A;  5IVG A;  3PYA A;  2Q9Y A;  2E8U A;  3PDE A;  5ILJ A;  3BNX A;  3WCH A;  3ZMC A;  1WL3 A;  4H5C F;  2E8T A;  1EZF A;  3LDW A;  4DI5 A;  2OPN A;  1V4K A;  3KRA A;  3LZ9 A;  3P8L A;  1V4J A;  3N6K F;  2E92 A;  3RMG A;  4RNQ A;  2Q58 A;  4LUU A;  2AZL A;  3ACY A;  5ILZ A;  3ACW A;  4LPH F;  5JUZ F;  4XQS F;  5ERO A;  3VJ8 A;  1DI1 A;  3QQV A;  3P5R A;  1VG2 A;  1DGP A;  5DGM F;  4RXD A;  1YHK A;  1HXG A;  2ZY1 A;  4N9U A;  3Q1O A;  3IPI A;  3EZ3 A;  4DZW A;  2J1O A;  3LK5 A;  5DHI A;  3SDQ A;  3WJO A;  4RXE A;  2AZK A;  5HN7 A;  3G4D A;  3WCF A;  4L2X F;  5KSX F;  1YYT A;  4NFK F;  4JXN A;  3LGK A;  5JA0 F;  5B0I A;  2Q80 A;  4K10 A;  3WCG A;  4OMH A;  1YYR A;  4P0V A;  4NFI F;  1KIY A;  1YV5 A;  4OGU A;  4GP1 A;  3M00 A;  3ZOU A;  3WCI A;  1HM7 A;  2E95 A;  3TFP A;  4KPJ A;  4MC8 A;  4DHD A;  5DZ2 A;  1WL1 A;  4E9Z A;  2PS4 A;  4N1Z F;  4NKF A;  5B0K A;  3CC9 A;  3NRI A;  2EWG A;  1YQ7 A;  3N5H F;  4LPG F;  1UBW A;  4OKZ A;  3Q2Q A;  3LGZ B;  3UCA A;  1HXC A;  5IMN A;  1JFA A;  3TS7 A;  5IN8 A;  2P1C A;  3WCC A;  2Z7I A;  2E94 A;  2F8C F;  1ZW5 A;  3RYW A;  2Q9Z A;  1WMW A;  4EA2 A;  4LXW A;  3N3D A;  2Z7H A;  5JV2 F;  2E91 A;  3LG5 A;  1V4I A;  4LZC A;  1VG4 A;  3ICZ A;  1FPS A;  3TC1 A;  2VF6 A;  4H5D F;  2Z52 A;  4LLT A;  2E8W A;  3OAC B;  5ILK A;  2O1O A;  3W7F A;  3KB9 A;  5ERN A;  3PKO A;  2H8O A;  3SDT A;  2ZCR A;  5B0M A;  4JXY A;  5DJV F;  3WEK A;  4KVI A;  4KVW A;  5DW7 A;  4LFG A;  3WCA A;  3PYB A;  3ID0 A; 
#chains in the Genus database with same CATH topology
 5IK9 A;  3OAB B;  1UBX A;  3WCJ A;  1PS1 A;  1RTR A;  1HXA A;  5IKH A;  1JFG A;  3S9V A;  4LTZ A;  3WCL A;  3DYG A;  2J1P A;  4Q23 A;  3WEF A;  2E8X A;  3B7L A;  4LOB A;  3ASX A;  3V1V A;  5HN9 A;  5ILH A;  3MAV A;  3LMD A;  4KVD A;  3KBK A;  3KRF B;  3WEJ A;  2FOR A;  2I19 A;  4XQT F;  3WCM A;  3WC9 A;  3AQC B;  3OYR A;  1YYQ A;  3NF2 A;  4LFV F;  3P8R A;  5JV1 F;  4GA3 A;  3N5J F;  3ICN A;  5AHU B;  2OA6 A;  4LTV A;  3ADZ A;  5HN8 A;  3AQ0 A;  1V4E A;  4F62 A;  5IM1 A;  3AQB B;  5ER8 A;  3KRO B;  3LSN A;  4JZB A;  3WEH A;  5E8L A;  2AET A;  5ERM A;  2E93 A;  5AFX A;  2ZEU A;  4KUX A;  1YJ4 A;  1VG6 A;  3VJE A;  1UBV A;  4KK2 A;  5DJR F;  3TFV A;  2RAH A;  3OAB A;  3WE9 A;  4HD1 A;  4KQS A;  1YHL A;  3DYF A;  3Q2Z A;  3RYE A;  5B0L A;  3SAE A;  3N49 F;  5C05 A;  5H9D A;  1KIZ A;  3EFQ A;  1N24 A;  3WEG A;  4H5E F;  4NUA A;  3M02 A;  2F7M F;  4DWB A;  5E8H A;  5AEL A;  4JVJ F;  2OGD A;  5A0J A;  4RYP A;  3SDR A;  3AE0 A;  4LIX A;  3BNY A;  3PH7 A;  4LLS A;  5I1U A;  5B00 A;  4PVY F;  3NPK A;  4OKM A;  2Z4V A;  2DH4 A;  5IMI A;  3V66 A;  5DHK A;  4MC3 A;  4WK5 A;  3SDV A;  3NPR A;  3M9U A;  2Z78 A;  4PVX F;  2F9K F;  1YYU A;  5A0K A;  5DIQ F;  3KRO A;  1RQJ A;  3N3L F;  3ACX A;  5DGS F;  4NKE A;  2ONG A;  4MC0 A;  3VJD A;  3N1W F;  3APZ A;  4P0X A;  5A0I A;  2QIS A;  4FJQ A;  2F92 F;  2PS6 A;  4KKM A;  4E9U A;  2Z4W A;  3CP6 A;  4UMJ A;  2ZCO A;  4JZX A;  3KRP B;  1RQI A;  3KRC B;  3P5P A;  5IMP A;  5IK6 A;  2ZCS A;  5B02 A;  3ICM A;  3CKE A;  3QKC A;  3VJA A;  4QPF A;  3WCE A;  3WEI A;  4LZ3 A;  3ICK A;  3N46 F;  3VJC A;  2Z4X A;  5IL3 A;  3LJI A;  3IBA A;  3N0G A;  4KQ5 A;  5AYP A;  1N21 A;  3G4F A;  4QXS F;  4LFE A;  4LA6 A;  3DYH A;  5EAT A;  2PS8 A;  3N45 F;  4EA1 A;  3TFN A;  4KVY A;  2E4O A;  4KPD A;  4DEM F;  4GP2 A;  4OMG A;  3OAC A;  5DJP F;  3Q30 A;  1WL2 A;  3M01 A;  4F6V A;  3N1V F;  3S4J A;  2FTZ A;  1VG3 A;  3P41 A;  2Z4Y A;  1VG7 A;  1YHM A;  2J5C A;  2PS5 A;  3LOM A;  3LEE A;  2F94 F;  3WJN A;  4KFA A;  3VJ9 A;  1V4H A;  4JYX A;  3LLW A;  1HM4 A;  5EAU A;  1N20 A;  2ONH A;  3ZCD A;  5CG5 A;  2AZJ A;  4KWD A;  1HX9 A;  3KRP A;  3ZL6 A;  3KRC A;  4DWG A;  3M0G A;  2E90 A;  5IKA A;  2F89 F;  3KRA B;  4KQU A;  3RBM A;  1WL0 A;  4RXA A;  1N23 A;  4NG6 A;  5HNA A;  2PS7 A;  4ZQ8 A;  3EGT A;  1YYS A;  4FP4 A;  4GAX A;  1UBY A;  3KRF A;  2ZCQ A;  4RXC A;  3WCB A;  5B0J A;  3WSA A;  5IL8 A;  3LVS A;  5E8K A;  5ILY A;  1N1Z A;  5IK0 A;  1N1B A;  3SDU A;  5B01 A;  2E8V A;  3WSB A;  2AEL A;  4XQR F;  3ZMB A;  2OPM A;  4LA5 A;  4NFJ F;  2AEK A;  3V1X A;  3WJK A;  3WCD A;  3MZV A;  1WY0 A;  5ILD A;  5CG6 A;  5ILI A;  3VJB A;  2F8Z F;  1WKZ A;  4F6X A;  5JV0 F;  5DGN F;  4P0W A;  4E1E A;  3N0F A;  2Z4Z A;  5EAS A;  5B03 A;  4DXJ A;  2Z50 A;  2ZEV A;  1N22 A;  4EA0 A;  4LZ0 A;  5IVG A;  3PYA A;  2Q9Y A;  2E8U A;  3PDE A;  5ILJ A;  3BNX A;  3WCH A;  3ZMC A;  1WL3 A;  4H5C F;  2E8T A;  1EZF A;  3LDW A;  4DI5 A;  2OPN A;  1V4K A;  3KRA A;  3LZ9 A;  3P8L A;  1V4J A;  3N6K F;  2E92 A;  3RMG A;  4RNQ A;  2Q58 A;  4LUU A;  2AZL A;  3ACY A;  5ILZ A;  3ACW A;  4LPH F;  5JUZ F;  4XQS F;  5ERO A;  3VJ8 A;  1DI1 A;  3QQV A;  3P5R A;  1VG2 A;  1DGP A;  5DGM F;  4RXD A;  1YHK A;  1HXG A;  2ZY1 A;  4N9U A;  3Q1O A;  3IPI A;  3EZ3 A;  4DZW A;  2J1O A;  3LK5 A;  5DHI A;  3SDQ A;  3WJO A;  4RXE A;  2AZK A;  5HN7 A;  3G4D A;  3WCF A;  4L2X F;  5KSX F;  1YYT A;  4NFK F;  4JXN A;  3LGK A;  5JA0 F;  5B0I A;  2Q80 A;  4K10 A;  3WCG A;  4OMH A;  1YYR A;  4P0V A;  4NFI F;  1KIY A;  1YV5 A;  4OGU A;  4GP1 A;  3M00 A;  3ZOU A;  3WCI A;  1HM7 A;  2E95 A;  3TFP A;  4KPJ A;  4MC8 A;  4DHD A;  5DZ2 A;  1WL1 A;  4E9Z A;  2PS4 A;  4N1Z F;  4NKF A;  5B0K A;  3CC9 A;  3NRI A;  2EWG A;  1YQ7 A;  3N5H F;  4LPG F;  1UBW A;  4OKZ A;  3Q2Q A;  3LGZ B;  3UCA A;  1HXC A;  5IMN A;  1JFA A;  3TS7 A;  5IN8 A;  2P1C A;  3WCC A;  2Z7I A;  2E94 A;  2F8C F;  1ZW5 A;  3RYW A;  2Q9Z A;  1WMW A;  4EA2 A;  4LXW A;  3N3D A;  2Z7H A;  5JV2 F;  2E91 A;  3LG5 A;  1V4I A;  4LZC A;  1VG4 A;  3ICZ A;  1FPS A;  3TC1 A;  2VF6 A;  4H5D F;  2Z52 A;  4LLT A;  2E8W A;  3OAC B;  5ILK A;  2O1O A;  3W7F A;  3KB9 A;  5ERN A;  3PKO A;  2H8O A;  3SDT A;  2ZCR A;  5B0M A;  4JXY A;  5DJV F;  3WEK A;  4KVI A;  4KVW A;  5DW7 A;  4LFG A;  3WCA A;  3PYB A;  3ID0 A; 
#chains in the Genus database with same CATH homology
 5IK9 A;  3OAB B;  1UBX A;  3WCJ A;  1PS1 A;  1RTR A;  1HXA A;  5IKH A;  1JFG A;  3S9V A;  4LTZ A;  3WCL A;  3DYG A;  2J1P A;  4Q23 A;  3WEF A;  2E8X A;  3B7L A;  4LOB A;  3ASX A;  3V1V A;  5HN9 A;  5ILH A;  3MAV A;  3LMD A;  4KVD A;  3KBK A;  3KRF B;  3WEJ A;  2FOR A;  2I19 A;  4XQT F;  3WCM A;  3WC9 A;  3AQC B;  3OYR A;  1YYQ A;  3NF2 A;  4LFV F;  3P8R A;  5JV1 F;  4GA3 A;  3N5J F;  3ICN A;  5AHU B;  2OA6 A;  4LTV A;  3ADZ A;  5HN8 A;  3AQ0 A;  1V4E A;  4F62 A;  5IM1 A;  3AQB B;  5ER8 A;  3KRO B;  3LSN A;  4JZB A;  3WEH A;  5E8L A;  2AET A;  5ERM A;  2E93 A;  5AFX A;  2ZEU A;  4KUX A;  1YJ4 A;  1VG6 A;  3VJE A;  1UBV A;  4KK2 A;  5DJR F;  3TFV A;  2RAH A;  3OAB A;  3WE9 A;  4HD1 A;  4KQS A;  1YHL A;  3DYF A;  3Q2Z A;  3RYE A;  5B0L A;  3SAE A;  3N49 F;  5C05 A;  5H9D A;  1KIZ A;  3EFQ A;  1N24 A;  3WEG A;  4H5E F;  4NUA A;  3M02 A;  2F7M F;  4DWB A;  5E8H A;  5AEL A;  4JVJ F;  2OGD A;  5A0J A;  4RYP A;  3SDR A;  3AE0 A;  4LIX A;  3BNY A;  3PH7 A;  4LLS A;  5I1U A;  5B00 A;  4PVY F;  3NPK A;  4OKM A;  2Z4V A;  2DH4 A;  5IMI A;  3V66 A;  5DHK A;  4MC3 A;  4WK5 A;  3SDV A;  3NPR A;  3M9U A;  2Z78 A;  4PVX F;  2F9K F;  1YYU A;  5A0K A;  5DIQ F;  3KRO A;  1RQJ A;  3N3L F;  3ACX A;  5DGS F;  4NKE A;  2ONG A;  4MC0 A;  3VJD A;  3N1W F;  3APZ A;  4P0X A;  5A0I A;  2QIS A;  4FJQ A;  2F92 F;  2PS6 A;  4KKM A;  4E9U A;  2Z4W A;  3CP6 A;  4UMJ A;  2ZCO A;  4JZX A;  3KRP B;  1RQI A;  3KRC B;  3P5P A;  5IMP A;  5IK6 A;  2ZCS A;  5B02 A;  3ICM A;  3CKE A;  3QKC A;  3VJA A;  4QPF A;  3WCE A;  3WEI A;  4LZ3 A;  3ICK A;  3N46 F;  3VJC A;  2Z4X A;  5IL3 A;  3LJI A;  3IBA A;  3N0G A;  4KQ5 A;  5AYP A;  1N21 A;  3G4F A;  4QXS F;  4LFE A;  4LA6 A;  3DYH A;  5EAT A;  2PS8 A;  3N45 F;  4EA1 A;  3TFN A;  4KVY A;  2E4O A;  4KPD A;  4DEM F;  4GP2 A;  4OMG A;  3OAC A;  5DJP F;  3Q30 A;  1WL2 A;  3M01 A;  4F6V A;  3N1V F;  3S4J A;  2FTZ A;  1VG3 A;  3P41 A;  2Z4Y A;  1VG7 A;  1YHM A;  2J5C A;  2PS5 A;  3LOM A;  3LEE A;  2F94 F;  3WJN A;  4KFA A;  3VJ9 A;  1V4H A;  4JYX A;  3LLW A;  1HM4 A;  5EAU A;  1N20 A;  2ONH A;  3ZCD A;  5CG5 A;  2AZJ A;  4KWD A;  1HX9 A;  3KRP A;  3ZL6 A;  3KRC A;  4DWG A;  3M0G A;  2E90 A;  5IKA A;  2F89 F;  3KRA B;  4KQU A;  3RBM A;  1WL0 A;  4RXA A;  1N23 A;  4NG6 A;  5HNA A;  2PS7 A;  4ZQ8 A;  3EGT A;  1YYS A;  4FP4 A;  4GAX A;  1UBY A;  3KRF A;  2ZCQ A;  4RXC A;  3WCB A;  5B0J A;  3WSA A;  5IL8 A;  3LVS A;  5E8K A;  5ILY A;  1N1Z A;  5IK0 A;  1N1B A;  3SDU A;  5B01 A;  2E8V A;  3WSB A;  2AEL A;  4XQR F;  3ZMB A;  2OPM A;  4LA5 A;  4NFJ F;  2AEK A;  3V1X A;  3WJK A;  3WCD A;  3MZV A;  1WY0 A;  5ILD A;  5CG6 A;  5ILI A;  3VJB A;  2F8Z F;  1WKZ A;  4F6X A;  5JV0 F;  5DGN F;  4P0W A;  4E1E A;  3N0F A;  2Z4Z A;  5EAS A;  5B03 A;  4DXJ A;  2Z50 A;  2ZEV A;  1N22 A;  4EA0 A;  4LZ0 A;  5IVG A;  3PYA A;  2Q9Y A;  2E8U A;  3PDE A;  5ILJ A;  3BNX A;  3WCH A;  3ZMC A;  1WL3 A;  4H5C F;  2E8T A;  1EZF A;  3LDW A;  4DI5 A;  2OPN A;  1V4K A;  3KRA A;  3LZ9 A;  3P8L A;  1V4J A;  3N6K F;  2E92 A;  3RMG A;  4RNQ A;  2Q58 A;  4LUU A;  2AZL A;  3ACY A;  5ILZ A;  3ACW A;  4LPH F;  5JUZ F;  4XQS F;  5ERO A;  3VJ8 A;  1DI1 A;  3QQV A;  3P5R A;  1VG2 A;  1DGP A;  5DGM F;  4RXD A;  1YHK A;  1HXG A;  2ZY1 A;  4N9U A;  3Q1O A;  3IPI A;  3EZ3 A;  4DZW A;  2J1O A;  3LK5 A;  5DHI A;  3SDQ A;  3WJO A;  4RXE A;  2AZK A;  5HN7 A;  3G4D A;  3WCF A;  4L2X F;  5KSX F;  1YYT A;  4NFK F;  4JXN A;  3LGK A;  5JA0 F;  5B0I A;  2Q80 A;  4K10 A;  3WCG A;  4OMH A;  1YYR A;  4P0V A;  4NFI F;  1KIY A;  1YV5 A;  4OGU A;  4GP1 A;  3M00 A;  3ZOU A;  3WCI A;  1HM7 A;  2E95 A;  3TFP A;  4KPJ A;  4MC8 A;  4DHD A;  5DZ2 A;  1WL1 A;  4E9Z A;  2PS4 A;  4N1Z F;  4NKF A;  5B0K A;  3CC9 A;  3NRI A;  2EWG A;  1YQ7 A;  3N5H F;  4LPG F;  1UBW A;  4OKZ A;  3Q2Q A;  3LGZ B;  3UCA A;  1HXC A;  5IMN A;  1JFA A;  3TS7 A;  5IN8 A;  2P1C A;  3WCC A;  2Z7I A;  2E94 A;  2F8C F;  1ZW5 A;  3RYW A;  2Q9Z A;  1WMW A;  4EA2 A;  4LXW A;  3N3D A;  2Z7H A;  5JV2 F;  2E91 A;  3LG5 A;  1V4I A;  4LZC A;  1VG4 A;  3ICZ A;  1FPS A;  3TC1 A;  2VF6 A;  4H5D F;  2Z52 A;  4LLT A;  2E8W A;  3OAC B;  5ILK A;  2O1O A;  3W7F A;  3KB9 A;  5ERN A;  3PKO A;  2H8O A;  3SDT A;  2ZCR A;  5B0M A;  4JXY A;  5DJV F;  3WEK A;  4KVI A;  4KVW A;  5DW7 A;  4LFG A;  3WCA A;  3PYB A;  3ID0 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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