4K10A

Crystal structure of leshmaniasis major farnesyl diphosphate synthase in complex with 3-fluoro-1-(2-hydroxy-2,2-diphosphonoethyl)pyridinium and mg2+
Total Genus 146
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
146
sequence length
361
structure length
358
Chain Sequence
MAHMERFQKVYEEVQEFLLGDAEKRFEMDVHRKGYLKSMMDTTCLGGKYNRGLCVVDVAEAMAKDTQMDAAAMERVLHDACVCGWMIEMLQAHFLVEDDIMDHSKTRRGKPCWYLHPGVTAQVAINDGLILLAWATQMALHYFADRPFLAEVLRVFHDVDLTTTIGQLYDVTSMVDSAKLDAKVAHANTTDYVEYTPFNHRRIVVYKTAYYTYWLPLVMGLLVSGTLEKVDKKATHKVAMVMGEYFQVQDDVMDCFTPPEKIGTDIEDAKCSWLAVTFLTTAPAEKVAEFKANYGSTDPAAVAVIKQLYTEQNLLARFEEYEKAVVAEVEQLIAALEAQNAAFAASVKVLWSKTYKRQ
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Transferase/transferase inhibitor
source organism Leishmania major
publication title Structural and thermodynamic basis of the inhibition of Leishmania major farnesyl diphosphate synthase by nitrogen-containing bisphosphonates.
pubmed doi rcsb
molecule keywords Farnesyl pyrophosphate synthase
total genus 146
structure length 358
sequence length 361
chains with identical sequence B, C, D
ec nomenclature ec 2.5.1.1: Dimethylallyltranstransferase.
pdb deposition date 2013-04-04

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00348 polyprenyl_synt Polyprenyl synthetase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.600.10 Mainly Alpha Orthogonal Bundle Farnesyl Diphosphate Synthase Farnesyl Diphosphate Synthase 4k10A00
4H5DF 4RNQA 3WE9A 3ZL6A 3LSNA 4RXCA 1KIZA 4JVJF 4LPGF 3LOMA 3ICKA 3KRAA 3WCHA 4DWGA 5B01A 4E1EA 3KRFA 3MAVA 3N5JF 2Z4WA 1HM4A 4RYPA 4OKMA 4NKEA 3OYRA 5HN9A 4P0XA 3SAEA 1N22A 4LZ3A 3PDEA 3SDRA 1YYTA 5JA0F 3WCDA 1VG6A 3V1VA 4K10A 3SDUA 3WEFA 3PYBA 3LMDA 1EZFA 3B7LA 4OMHA 2PS7A 3N5HF 3TFNA 3G4DA 2Z7HA 3N0FA 4KVWA 3RBMA 3WCMA 4EA2A 3LG5A 3WCFA 5A0KA 5DGNF 1RTRA 1VG2A 4DEMF 2Z4ZA 2VF6A 5JV1F 3OABB 5ILJA 2OA6A 1YYRA 3N49F 3SDQA 4H5EF 1UBVA 2ZCQA 1UBXA 4KPDA 3KRAB 5DIQF 3BNXA 5IL8A 4NFKF 3KRFB 1RQIA 4RXDA 5H9DA 3VJ8A 5AELA 4E9UA 3V1XA 4JXNA 3IPIA 1V4EA 1DGPA 2OGDA 2F94F 5B0LA 4P0VA 2ZY1A 5DGSF 3NF2A 5IK9A 5EROA 5IN8A 3OACB 5E8HA 3TC1A 3P5PA 2E4OA 3V66A 4E9ZA 4LLTA 3Q2ZA 2FTZA 3ADZA 2E93A 5ER8A 3CC9A 3APZA 3G4FA 3M00A 4ZQ8A 5JV0F 3KB9A 3Q2QA 3LVSA 3PKOA 1DI1A 1FPSA 1WY0A 4PVXF 4FJQA 3M9UA 1KIYA 5AFXA 2H8OA 1YYUA 3ACWA 3EGTA 5EATA 5IK0A 2AZJA 4DHDA 1PS1A 3ZMBA 4LIXA 2J1PA 3N45F 2Z7IA 4NKFA 1UBWA 4KPJA 3WSAA 3WEJA 5ILKA 3ACYA 4RXAA 1YJ4A 3VJAA 3WSBA 3WJOA 2AZKA 3WCCA 3DYFA 5B03A 3CKEA 3QQVA 1JFGA 1HXAA 2E8UA 2RAHA 5ILYA 1YHMA 3WEHA 3WCJA 2Z52A 5AHUB 4LPHF 1N20A 5AYPA 3SDVA 5HN8A 4JZBA 3Q30A 5ILHA 3LLWA 1V4IA 1HM7A 5KSXF 4QXSF 3N1WF 3RYEA 5IMIA 2E95A 5DZ2A 2Q9ZA 3N0GA 4EA1A 4NUAA 3OACA 1RQJA 3DYGA 3NPRA 1N21A 3AQ0A 3KRCA 5HN7A 3WEKA 1YHLA 5A0JA 3EZ3A 3RYWA 3N3LF 2F7MF 3AE0A 4KQUA 3Q1OA 1VG4A 3KRPA 4KK2A 1YYSA 4P0WA 3W7FA 5B02A 2AETA 3LGZB 4H5CF 4NFIF 4DZWA 3ICMA 4LFGA 5IMNA 4F62A 4LA6A 3WEIA 5IMPA 2PS4A 4KVDA 2F89F 2F8ZF 1HXCA 4LFVF 3RMGA 3VJCA 3DYHA 2J5CA 5CG5A 4LTZA 3ZMCA 4OMGA 3UCAA 3P41A 3KBKA 3CP6A 4DI5A 3ZCDA 4LUUA 2OPNA 5A0IA 3KRCB 2AELA 4LZCA 1N23A 4EA0A 3QKCA 4UMJA 5CG6A 5EASA 3WCEA 4JZXA 4PVYF 5DHIA 3KRPB 1YYQA 3EFQA 3WCIA 4DXJA 3M0GA 1ZW5A 2FORA 3LK5A 3NRIA 3LZ9A 4FP4A 3ICZA 3VJEA 2ZCRA 2ZEVA 3WJNA 2F9KF 3LGKA 4LTVA 1YHKA 4Q23A 4GP1A 1YV5A 3ZOUA 2ZEUA 5E8LA 3VJDA 1V4KA 2P1CA 3LDWA 1WMWA 4NG6A 4LLSA 5ILIA 5DJVF 1WL0A 5B00A 2J1OA 5C05A 2ZCSA 3TFPA 4GAXA 4JYXA 4F6XA 3BNYA 2PS8A 1UBYA 5IVGA 2E94A 5ERNA 5JUZF 4MC8A 4OKZA 3WC9A 5ILDA 1V4HA 3TFVA 2E90A 3KROA 2Z78A 3LEEA 1N24A 1JFAA 2O1OA 2Q9YA 5DGMF 1VG7A 1WL2A 1HXGA 4KKMA 4DWBA 4KQSA 4L2XF 5IKAA 3IBAA 2DH4A 4HD1A 4QPFA 3WJKA 5B0IA 1WKZA 2PS6A 4F6VA 5EAUA 5I1UA 3WCAA 3ICNA 3WCLA 2F8CF 5IM1A 5IK6A 4MC3A 4LZ0A 1WL1A 2ONGA 4RXEA 5B0KA 2Z4VA 3AQCB 3NPKA 4N1ZF 4WK5A 3P5RA 3SDTA 3WCGA 3VJ9A 5DJRF 5DW7A 3PH7A 3P8RA 2E8WA 2QISA 3ACXA 1N1BA 4MC0A 4XQTF 2E8VA 3KROB 5IL3A 2AEKA 3P8LA 4KWDA 4KVIA 4LFEA 2AZLA 2EWGA 4OGUA 3N3DA 2E91A 5DHKA 3N6KF 3VJBA 1HX9A 3N1VF 3ASXA 4GP2A 2E92A 3ID0A 3S9VA 4N9UA 1V4JA 3TS7A 5IKHA 2Z4XA 4LXWA 5HNAA 2ZCOA 3WCBA 1VG3A 2Z50A 4KFAA 3WEGA 3MZVA 2Q80A 5B0JA 3N46F 4KUXA 5ILZA 2F92F 3AQBB 5B0MA 5ERMA 4KVYA 4XQSF 3M02A 4GA3A 2E8TA 2PS5A 2I19A 3M01A 4NFJF 4XQRF 3LJIA 4JXYA 2OPMA 2Q58A 5E8KA 2Z4YA 5DJPF 3PYAA 4LOBA 5JV2F 1WL3A 3S4JA 4KQ5A 2ONHA 3OABA 4LA5A 1N1ZA 2E8XA 1YQ7A
chains in the Genus database with same CATH superfamily
4H5DF 4RNQA 3WE9A 3ZL6A 3LSNA 4RXCA 1KIZA 4JVJF 4LPGF 3LOMA 3ICKA 3KRAA 3WCHA 4DWGA 5B01A 4E1EA 3KRFA 3MAVA 3N5JF 2Z4WA 1HM4A 4RYPA 4OKMA 4NKEA 3OYRA 5HN9A 4P0XA 3SAEA 1N22A 4LZ3A 3PDEA 3SDRA 1YYTA 5JA0F 3WCDA 1VG6A 3V1VA 4K10A 3SDUA 3WEFA 3PYBA 3LMDA 1EZFA 3B7LA 4OMHA 2PS7A 3N5HF 3TFNA 3G4DA 2Z7HA 3N0FA 4KVWA 3RBMA 3WCMA 4EA2A 3LG5A 3WCFA 5A0KA 5DGNF 1RTRA 1VG2A 4DEMF 2Z4ZA 2VF6A 5JV1F 3OABB 5ILJA 2OA6A 1YYRA 3N49F 3SDQA 4H5EF 1UBVA 2ZCQA 1UBXA 4KPDA 3KRAB 5DIQF 3BNXA 5IL8A 4NFKF 3KRFB 1RQIA 4RXDA 5H9DA 3VJ8A 5AELA 4E9UA 3V1XA 4JXNA 3IPIA 1V4EA 1DGPA 2OGDA 2F94F 5B0LA 4P0VA 2ZY1A 5DGSF 3NF2A 5IK9A 5EROA 5IN8A 3OACB 5E8HA 3TC1A 3P5PA 2E4OA 3V66A 4E9ZA 4LLTA 3Q2ZA 2FTZA 3ADZA 2E93A 5ER8A 3CC9A 3APZA 3G4FA 3M00A 4ZQ8A 5JV0F 3KB9A 3Q2QA 3LVSA 3PKOA 1DI1A 1FPSA 1WY0A 4PVXF 4FJQA 3M9UA 1KIYA 5AFXA 2H8OA 1YYUA 3ACWA 3EGTA 5EATA 5IK0A 2AZJA 4DHDA 1PS1A 3ZMBA 4LIXA 2J1PA 3N45F 2Z7IA 4NKFA 1UBWA 4KPJA 3WSAA 3WEJA 5ILKA 3ACYA 4RXAA 1YJ4A 3VJAA 3WSBA 3WJOA 2AZKA 3WCCA 3DYFA 5B03A 3CKEA 3QQVA 1JFGA 1HXAA 2E8UA 2RAHA 5ILYA 1YHMA 3WEHA 3WCJA 2Z52A 5AHUB 4LPHF 1N20A 5AYPA 3SDVA 5HN8A 4JZBA 3Q30A 5ILHA 3LLWA 1V4IA 1HM7A 5KSXF 4QXSF 3N1WF 3RYEA 5IMIA 2E95A 5DZ2A 2Q9ZA 3N0GA 4EA1A 4NUAA 3OACA 1RQJA 3DYGA 3NPRA 1N21A 3AQ0A 3KRCA 5HN7A 3WEKA 1YHLA 5A0JA 3EZ3A 3RYWA 3N3LF 2F7MF 3AE0A 4KQUA 3Q1OA 1VG4A 3KRPA 4KK2A 1YYSA 4P0WA 3W7FA 5B02A 2AETA 3LGZB 4H5CF 4NFIF 4DZWA 3ICMA 4LFGA 5IMNA 4F62A 4LA6A 3WEIA 5IMPA 2PS4A 4KVDA 2F89F 2F8ZF 1HXCA 4LFVF 3RMGA 3VJCA 3DYHA 2J5CA 5CG5A 4LTZA 3ZMCA 4OMGA 3UCAA 3P41A 3KBKA 3CP6A 4DI5A 3ZCDA 4LUUA 2OPNA 5A0IA 3KRCB 2AELA 4LZCA 1N23A 4EA0A 3QKCA 4UMJA 5CG6A 5EASA 3WCEA 4JZXA 4PVYF 5DHIA 3KRPB 1YYQA 3EFQA 3WCIA 4DXJA 3M0GA 1ZW5A 2FORA 3LK5A 3NRIA 3LZ9A 4FP4A 3ICZA 3VJEA 2ZCRA 2ZEVA 3WJNA 2F9KF 3LGKA 4LTVA 1YHKA 4Q23A 4GP1A 1YV5A 3ZOUA 2ZEUA 5E8LA 3VJDA 1V4KA 2P1CA 3LDWA 1WMWA 4NG6A 4LLSA 5ILIA 5DJVF 1WL0A 5B00A 2J1OA 5C05A 2ZCSA 3TFPA 4GAXA 4JYXA 4F6XA 3BNYA 2PS8A 1UBYA 5IVGA 2E94A 5ERNA 5JUZF 4MC8A 4OKZA 3WC9A 5ILDA 1V4HA 3TFVA 2E90A 3KROA 2Z78A 3LEEA 1N24A 1JFAA 2O1OA 2Q9YA 5DGMF 1VG7A 1WL2A 1HXGA 4KKMA 4DWBA 4KQSA 4L2XF 5IKAA 3IBAA 2DH4A 4HD1A 4QPFA 3WJKA 5B0IA 1WKZA 2PS6A 4F6VA 5EAUA 5I1UA 3WCAA 3ICNA 3WCLA 2F8CF 5IM1A 5IK6A 4MC3A 4LZ0A 1WL1A 2ONGA 4RXEA 5B0KA 2Z4VA 3AQCB 3NPKA 4N1ZF 4WK5A 3P5RA 3SDTA 3WCGA 3VJ9A 5DJRF 5DW7A 3PH7A 3P8RA 2E8WA 2QISA 3ACXA 1N1BA 4MC0A 4XQTF 2E8VA 3KROB 5IL3A 2AEKA 3P8LA 4KWDA 4KVIA 4LFEA 2AZLA 2EWGA 4OGUA 3N3DA 2E91A 5DHKA 3N6KF 3VJBA 1HX9A 3N1VF 3ASXA 4GP2A 2E92A 3ID0A 3S9VA 4N9UA 1V4JA 3TS7A 5IKHA 2Z4XA 4LXWA 5HNAA 2ZCOA 3WCBA 1VG3A 2Z50A 4KFAA 3WEGA 3MZVA 2Q80A 5B0JA 3N46F 4KUXA 5ILZA 2F92F 3AQBB 5B0MA 5ERMA 4KVYA 4XQSF 3M02A 4GA3A 2E8TA 2PS5A 2I19A 3M01A 4NFJF 4XQRF 3LJIA 4JXYA 2OPMA 2Q58A 5E8KA 2Z4YA 5DJPF 3PYAA 4LOBA 5JV2F 1WL3A 3S4JA 4KQ5A 2ONHA 3OABA 4LA5A 1N1ZA 2E8XA 1YQ7A
chains in the Genus database with same CATH topology
4H5DF 4RNQA 3WE9A 3ZL6A 3LSNA 4RXCA 1KIZA 4JVJF 4LPGF 3LOMA 3ICKA 3KRAA 3WCHA 4DWGA 5B01A 4E1EA 3KRFA 3MAVA 3N5JF 2Z4WA 1HM4A 4RYPA 4OKMA 4NKEA 3OYRA 5HN9A 4P0XA 3SAEA 1N22A 4LZ3A 3PDEA 3SDRA 1YYTA 5JA0F 3WCDA 1VG6A 3V1VA 4K10A 3SDUA 3WEFA 3PYBA 3LMDA 1EZFA 3B7LA 4OMHA 2PS7A 3N5HF 3TFNA 3G4DA 2Z7HA 3N0FA 4KVWA 3RBMA 3WCMA 4EA2A 3LG5A 3WCFA 5A0KA 5DGNF 1RTRA 1VG2A 4DEMF 2Z4ZA 2VF6A 5JV1F 3OABB 5ILJA 2OA6A 1YYRA 3N49F 3SDQA 4H5EF 1UBVA 2ZCQA 1UBXA 4KPDA 3KRAB 5DIQF 3BNXA 5IL8A 4NFKF 3KRFB 1RQIA 4RXDA 5H9DA 3VJ8A 5AELA 4E9UA 3V1XA 4JXNA 3IPIA 1V4EA 1DGPA 2OGDA 2F94F 5B0LA 4P0VA 2ZY1A 5DGSF 3NF2A 5IK9A 5EROA 5IN8A 3OACB 5E8HA 3TC1A 3P5PA 2E4OA 3V66A 4E9ZA 4LLTA 3Q2ZA 2FTZA 3ADZA 2E93A 5ER8A 3CC9A 3APZA 3G4FA 3M00A 4ZQ8A 5JV0F 3KB9A 3Q2QA 3LVSA 3PKOA 1DI1A 1FPSA 1WY0A 4PVXF 4FJQA 3M9UA 1KIYA 5AFXA 2H8OA 1YYUA 3ACWA 3EGTA 5EATA 5IK0A 2AZJA 4DHDA 1PS1A 3ZMBA 4LIXA 2J1PA 3N45F 2Z7IA 4NKFA 1UBWA 4KPJA 3WSAA 3WEJA 5ILKA 3ACYA 4RXAA 1YJ4A 3VJAA 3WSBA 3WJOA 2AZKA 3WCCA 3DYFA 5B03A 3CKEA 3QQVA 1JFGA 1HXAA 2E8UA 2RAHA 5ILYA 1YHMA 3WEHA 3WCJA 2Z52A 5AHUB 4LPHF 1N20A 5AYPA 3SDVA 5HN8A 4JZBA 3Q30A 5ILHA 3LLWA 1V4IA 1HM7A 5KSXF 4QXSF 3N1WF 3RYEA 5IMIA 2E95A 5DZ2A 2Q9ZA 3N0GA 4EA1A 4NUAA 3OACA 1RQJA 3DYGA 3NPRA 1N21A 3AQ0A 3KRCA 5HN7A 3WEKA 1YHLA 5A0JA 3EZ3A 3RYWA 3N3LF 2F7MF 3AE0A 4KQUA 3Q1OA 1VG4A 3KRPA 4KK2A 1YYSA 4P0WA 3W7FA 5B02A 2AETA 3LGZB 4H5CF 4NFIF 4DZWA 3ICMA 4LFGA 5IMNA 4F62A 4LA6A 3WEIA 5IMPA 2PS4A 4KVDA 2F89F 2F8ZF 1HXCA 4LFVF 3RMGA 3VJCA 3DYHA 2J5CA 5CG5A 4LTZA 3ZMCA 4OMGA 3UCAA 3P41A 3KBKA 3CP6A 4DI5A 3ZCDA 4LUUA 2OPNA 5A0IA 3KRCB 2AELA 4LZCA 1N23A 4EA0A 3QKCA 4UMJA 5CG6A 5EASA 3WCEA 4JZXA 4PVYF 5DHIA 3KRPB 1YYQA 3EFQA 3WCIA 4DXJA 3M0GA 1ZW5A 2FORA 3LK5A 3NRIA 3LZ9A 4FP4A 3ICZA 3VJEA 2ZCRA 2ZEVA 3WJNA 2F9KF 3LGKA 4LTVA 1YHKA 4Q23A 4GP1A 1YV5A 3ZOUA 2ZEUA 5E8LA 3VJDA 1V4KA 2P1CA 3LDWA 1WMWA 4NG6A 4LLSA 5ILIA 5DJVF 1WL0A 5B00A 2J1OA 5C05A 2ZCSA 3TFPA 4GAXA 4JYXA 4F6XA 3BNYA 2PS8A 1UBYA 5IVGA 2E94A 5ERNA 5JUZF 4MC8A 4OKZA 3WC9A 5ILDA 1V4HA 3TFVA 2E90A 3KROA 2Z78A 3LEEA 1N24A 1JFAA 2O1OA 2Q9YA 5DGMF 1VG7A 1WL2A 1HXGA 4KKMA 4DWBA 4KQSA 4L2XF 5IKAA 3IBAA 2DH4A 4HD1A 4QPFA 3WJKA 5B0IA 1WKZA 2PS6A 4F6VA 5EAUA 5I1UA 3WCAA 3ICNA 3WCLA 2F8CF 5IM1A 5IK6A 4MC3A 4LZ0A 1WL1A 2ONGA 4RXEA 5B0KA 2Z4VA 3AQCB 3NPKA 4N1ZF 4WK5A 3P5RA 3SDTA 3WCGA 3VJ9A 5DJRF 5DW7A 3PH7A 3P8RA 2E8WA 2QISA 3ACXA 1N1BA 4MC0A 4XQTF 2E8VA 3KROB 5IL3A 2AEKA 3P8LA 4KWDA 4KVIA 4LFEA 2AZLA 2EWGA 4OGUA 3N3DA 2E91A 5DHKA 3N6KF 3VJBA 1HX9A 3N1VF 3ASXA 4GP2A 2E92A 3ID0A 3S9VA 4N9UA 1V4JA 3TS7A 5IKHA 2Z4XA 4LXWA 5HNAA 2ZCOA 3WCBA 1VG3A 2Z50A 4KFAA 3WEGA 3MZVA 2Q80A 5B0JA 3N46F 4KUXA 5ILZA 2F92F 3AQBB 5B0MA 5ERMA 4KVYA 4XQSF 3M02A 4GA3A 2E8TA 2PS5A 2I19A 3M01A 4NFJF 4XQRF 3LJIA 4JXYA 2OPMA 2Q58A 5E8KA 2Z4YA 5DJPF 3PYAA 4LOBA 5JV2F 1WL3A 3S4JA 4KQ5A 2ONHA 3OABA 4LA5A 1N1ZA 2E8XA 1YQ7A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4H5D F;  4RNQ A;  3WE9 A;  3ZL6 A;  3LSN A;  4RXC A;  1KIZ A;  4JVJ F;  4LPG F;  3LOM A;  3ICK A;  3KRA A;  3WCH A;  4DWG A;  5B01 A;  4E1E A;  3KRF A;  3MAV A;  3N5J F;  2Z4W A;  1HM4 A;  4RYP A;  4OKM A;  4NKE A;  3OYR A;  5HN9 A;  4P0X A;  3SAE A;  1N22 A;  4LZ3 A;  3PDE A;  3SDR A;  1YYT A;  5JA0 F;  3WCD A;  1VG6 A;  3V1V A;  4K10 A;  3SDU A;  3WEF A;  3PYB A;  3LMD A;  1EZF A;  3B7L A;  4OMH A;  2PS7 A;  3N5H F;  3TFN A;  3G4D A;  2Z7H A;  3N0F A;  4KVW A;  3RBM A;  3WCM A;  4EA2 A;  3LG5 A;  3WCF A;  5A0K A;  5DGN F;  1RTR A;  1VG2 A;  4DEM F;  2Z4Z A;  2VF6 A;  5JV1 F;  3OAB B;  5ILJ A;  2OA6 A;  1YYR A;  3N49 F;  3SDQ A;  4H5E F;  1UBV A;  2ZCQ A;  1UBX A;  4KPD A;  3KRA B;  5DIQ F;  3BNX A;  5IL8 A;  4NFK F;  3KRF B;  1RQI A;  4RXD A;  5H9D A;  3VJ8 A;  5AEL A;  4E9U A;  3V1X A;  4JXN A;  3IPI A;  1V4E A;  1DGP A;  2OGD A;  2F94 F;  5B0L A;  4P0V A;  2ZY1 A;  5DGS F;  3NF2 A;  5IK9 A;  5ERO A;  5IN8 A;  3OAC B;  5E8H A;  3TC1 A;  3P5P A;  2E4O A;  3V66 A;  4E9Z A;  4LLT A;  3Q2Z A;  2FTZ A;  3ADZ A;  2E93 A;  5ER8 A;  3CC9 A;  3APZ A;  3G4F A;  3M00 A;  4ZQ8 A;  5JV0 F;  3KB9 A;  3Q2Q A;  3LVS A;  3PKO A;  1DI1 A;  1FPS A;  1WY0 A;  4PVX F;  4FJQ A;  3M9U A;  1KIY A;  5AFX A;  2H8O A;  1YYU A;  3ACW A;  3EGT A;  5EAT A;  5IK0 A;  2AZJ A;  4DHD A;  1PS1 A;  3ZMB A;  4LIX A;  2J1P A;  3N45 F;  2Z7I A;  4NKF A;  1UBW A;  4KPJ A;  3WSA A;  3WEJ A;  5ILK A;  3ACY A;  4RXA A;  1YJ4 A;  3VJA A;  3WSB A;  3WJO A;  2AZK A;  3WCC A;  3DYF A;  5B03 A;  3CKE A;  3QQV A;  1JFG A;  1HXA A;  2E8U A;  2RAH A;  5ILY A;  1YHM A;  3WEH A;  3WCJ A;  2Z52 A;  5AHU B;  4LPH F;  1N20 A;  5AYP A;  3SDV A;  5HN8 A;  4JZB A;  3Q30 A;  5ILH A;  3LLW A;  1V4I A;  1HM7 A;  5KSX F;  4QXS F;  3N1W F;  3RYE A;  5IMI A;  2E95 A;  5DZ2 A;  2Q9Z A;  3N0G A;  4EA1 A;  4NUA A;  3OAC A;  1RQJ A;  3DYG A;  3NPR A;  1N21 A;  3AQ0 A;  3KRC A;  5HN7 A;  3WEK A;  1YHL A;  5A0J A;  3EZ3 A;  3RYW A;  3N3L F;  2F7M F;  3AE0 A;  4KQU A;  3Q1O A;  1VG4 A;  3KRP A;  4KK2 A;  1YYS A;  4P0W A;  3W7F A;  5B02 A;  2AET A;  3LGZ B;  4H5C F;  4NFI F;  4DZW A;  3ICM A;  4LFG A;  5IMN A;  4F62 A;  4LA6 A;  3WEI A;  5IMP A;  2PS4 A;  4KVD A;  2F89 F;  2F8Z F;  1HXC A;  4LFV F;  3RMG A;  3VJC A;  3DYH A;  2J5C A;  5CG5 A;  4LTZ A;  3ZMC A;  4OMG A;  3UCA A;  3P41 A;  3KBK A;  3CP6 A;  4DI5 A;  3ZCD A;  4LUU A;  2OPN A;  5A0I A;  3KRC B;  2AEL A;  4LZC A;  1N23 A;  4EA0 A;  3QKC A;  4UMJ A;  5CG6 A;  5EAS A;  3WCE A;  4JZX A;  4PVY F;  5DHI A;  3KRP B;  1YYQ A;  3EFQ A;  3WCI A;  4DXJ A;  3M0G A;  1ZW5 A;  2FOR A;  3LK5 A;  3NRI A;  3LZ9 A;  4FP4 A;  3ICZ A;  3VJE A;  2ZCR A;  2ZEV A;  3WJN A;  2F9K F;  3LGK A;  4LTV A;  1YHK A;  4Q23 A;  4GP1 A;  1YV5 A;  3ZOU A;  2ZEU A;  5E8L A;  3VJD A;  1V4K A;  2P1C A;  3LDW A;  1WMW A;  4NG6 A;  4LLS A;  5ILI A;  5DJV F;  1WL0 A;  5B00 A;  2J1O A;  5C05 A;  2ZCS A;  3TFP A;  4GAX A;  4JYX A;  4F6X A;  3BNY A;  2PS8 A;  1UBY A;  5IVG A;  2E94 A;  5ERN A;  5JUZ F;  4MC8 A;  4OKZ A;  3WC9 A;  5ILD A;  1V4H A;  3TFV A;  2E90 A;  3KRO A;  2Z78 A;  3LEE A;  1N24 A;  1JFA A;  2O1O A;  2Q9Y A;  5DGM F;  1VG7 A;  1WL2 A;  1HXG A;  4KKM A;  4DWB A;  4KQS A;  4L2X F;  5IKA A;  3IBA A;  2DH4 A;  4HD1 A;  4QPF A;  3WJK A;  5B0I A;  1WKZ A;  2PS6 A;  4F6V A;  5EAU A;  5I1U A;  3WCA A;  3ICN A;  3WCL A;  2F8C F;  5IM1 A;  5IK6 A;  4MC3 A;  4LZ0 A;  1WL1 A;  2ONG A;  4RXE A;  5B0K A;  2Z4V A;  3AQC B;  3NPK A;  4N1Z F;  4WK5 A;  3P5R A;  3SDT A;  3WCG A;  3VJ9 A;  5DJR F;  5DW7 A;  3PH7 A;  3P8R A;  2E8W A;  2QIS A;  3ACX A;  1N1B A;  4MC0 A;  4XQT F;  2E8V A;  3KRO B;  5IL3 A;  2AEK A;  3P8L A;  4KWD A;  4KVI A;  4LFE A;  2AZL A;  2EWG A;  4OGU A;  3N3D A;  2E91 A;  5DHK A;  3N6K F;  3VJB A;  1HX9 A;  3N1V F;  3ASX A;  4GP2 A;  2E92 A;  3ID0 A;  3S9V A;  4N9U A;  1V4J A;  3TS7 A;  5IKH A;  2Z4X A;  4LXW A;  5HNA A;  2ZCO A;  3WCB A;  1VG3 A;  2Z50 A;  4KFA A;  3WEG A;  3MZV A;  2Q80 A;  5B0J A;  3N46 F;  4KUX A;  5ILZ A;  2F92 F;  3AQB B;  5B0M A;  5ERM A;  4KVY A;  4XQS F;  3M02 A;  4GA3 A;  2E8T A;  2PS5 A;  2I19 A;  3M01 A;  4NFJ F;  4XQR F;  3LJI A;  4JXY A;  2OPM A;  2Q58 A;  5E8K A;  2Z4Y A;  5DJP F;  3PYA A;  4LOB A;  5JV2 F;  1WL3 A;  3S4J A;  4KQ5 A;  2ONH A;  3OAB A;  4LA5 A;  1N1Z A;  2E8X A;  1YQ7 A; 
#chains in the Genus database with same CATH topology
 4H5D F;  4RNQ A;  3WE9 A;  3ZL6 A;  3LSN A;  4RXC A;  1KIZ A;  4JVJ F;  4LPG F;  3LOM A;  3ICK A;  3KRA A;  3WCH A;  4DWG A;  5B01 A;  4E1E A;  3KRF A;  3MAV A;  3N5J F;  2Z4W A;  1HM4 A;  4RYP A;  4OKM A;  4NKE A;  3OYR A;  5HN9 A;  4P0X A;  3SAE A;  1N22 A;  4LZ3 A;  3PDE A;  3SDR A;  1YYT A;  5JA0 F;  3WCD A;  1VG6 A;  3V1V A;  4K10 A;  3SDU A;  3WEF A;  3PYB A;  3LMD A;  1EZF A;  3B7L A;  4OMH A;  2PS7 A;  3N5H F;  3TFN A;  3G4D A;  2Z7H A;  3N0F A;  4KVW A;  3RBM A;  3WCM A;  4EA2 A;  3LG5 A;  3WCF A;  5A0K A;  5DGN F;  1RTR A;  1VG2 A;  4DEM F;  2Z4Z A;  2VF6 A;  5JV1 F;  3OAB B;  5ILJ A;  2OA6 A;  1YYR A;  3N49 F;  3SDQ A;  4H5E F;  1UBV A;  2ZCQ A;  1UBX A;  4KPD A;  3KRA B;  5DIQ F;  3BNX A;  5IL8 A;  4NFK F;  3KRF B;  1RQI A;  4RXD A;  5H9D A;  3VJ8 A;  5AEL A;  4E9U A;  3V1X A;  4JXN A;  3IPI A;  1V4E A;  1DGP A;  2OGD A;  2F94 F;  5B0L A;  4P0V A;  2ZY1 A;  5DGS F;  3NF2 A;  5IK9 A;  5ERO A;  5IN8 A;  3OAC B;  5E8H A;  3TC1 A;  3P5P A;  2E4O A;  3V66 A;  4E9Z A;  4LLT A;  3Q2Z A;  2FTZ A;  3ADZ A;  2E93 A;  5ER8 A;  3CC9 A;  3APZ A;  3G4F A;  3M00 A;  4ZQ8 A;  5JV0 F;  3KB9 A;  3Q2Q A;  3LVS A;  3PKO A;  1DI1 A;  1FPS A;  1WY0 A;  4PVX F;  4FJQ A;  3M9U A;  1KIY A;  5AFX A;  2H8O A;  1YYU A;  3ACW A;  3EGT A;  5EAT A;  5IK0 A;  2AZJ A;  4DHD A;  1PS1 A;  3ZMB A;  4LIX A;  2J1P A;  3N45 F;  2Z7I A;  4NKF A;  1UBW A;  4KPJ A;  3WSA A;  3WEJ A;  5ILK A;  3ACY A;  4RXA A;  1YJ4 A;  3VJA A;  3WSB A;  3WJO A;  2AZK A;  3WCC A;  3DYF A;  5B03 A;  3CKE A;  3QQV A;  1JFG A;  1HXA A;  2E8U A;  2RAH A;  5ILY A;  1YHM A;  3WEH A;  3WCJ A;  2Z52 A;  5AHU B;  4LPH F;  1N20 A;  5AYP A;  3SDV A;  5HN8 A;  4JZB A;  3Q30 A;  5ILH A;  3LLW A;  1V4I A;  1HM7 A;  5KSX F;  4QXS F;  3N1W F;  3RYE A;  5IMI A;  2E95 A;  5DZ2 A;  2Q9Z A;  3N0G A;  4EA1 A;  4NUA A;  3OAC A;  1RQJ A;  3DYG A;  3NPR A;  1N21 A;  3AQ0 A;  3KRC A;  5HN7 A;  3WEK A;  1YHL A;  5A0J A;  3EZ3 A;  3RYW A;  3N3L F;  2F7M F;  3AE0 A;  4KQU A;  3Q1O A;  1VG4 A;  3KRP A;  4KK2 A;  1YYS A;  4P0W A;  3W7F A;  5B02 A;  2AET A;  3LGZ B;  4H5C F;  4NFI F;  4DZW A;  3ICM A;  4LFG A;  5IMN A;  4F62 A;  4LA6 A;  3WEI A;  5IMP A;  2PS4 A;  4KVD A;  2F89 F;  2F8Z F;  1HXC A;  4LFV F;  3RMG A;  3VJC A;  3DYH A;  2J5C A;  5CG5 A;  4LTZ A;  3ZMC A;  4OMG A;  3UCA A;  3P41 A;  3KBK A;  3CP6 A;  4DI5 A;  3ZCD A;  4LUU A;  2OPN A;  5A0I A;  3KRC B;  2AEL A;  4LZC A;  1N23 A;  4EA0 A;  3QKC A;  4UMJ A;  5CG6 A;  5EAS A;  3WCE A;  4JZX A;  4PVY F;  5DHI A;  3KRP B;  1YYQ A;  3EFQ A;  3WCI A;  4DXJ A;  3M0G A;  1ZW5 A;  2FOR A;  3LK5 A;  3NRI A;  3LZ9 A;  4FP4 A;  3ICZ A;  3VJE A;  2ZCR A;  2ZEV A;  3WJN A;  2F9K F;  3LGK A;  4LTV A;  1YHK A;  4Q23 A;  4GP1 A;  1YV5 A;  3ZOU A;  2ZEU A;  5E8L A;  3VJD A;  1V4K A;  2P1C A;  3LDW A;  1WMW A;  4NG6 A;  4LLS A;  5ILI A;  5DJV F;  1WL0 A;  5B00 A;  2J1O A;  5C05 A;  2ZCS A;  3TFP A;  4GAX A;  4JYX A;  4F6X A;  3BNY A;  2PS8 A;  1UBY A;  5IVG A;  2E94 A;  5ERN A;  5JUZ F;  4MC8 A;  4OKZ A;  3WC9 A;  5ILD A;  1V4H A;  3TFV A;  2E90 A;  3KRO A;  2Z78 A;  3LEE A;  1N24 A;  1JFA A;  2O1O A;  2Q9Y A;  5DGM F;  1VG7 A;  1WL2 A;  1HXG A;  4KKM A;  4DWB A;  4KQS A;  4L2X F;  5IKA A;  3IBA A;  2DH4 A;  4HD1 A;  4QPF A;  3WJK A;  5B0I A;  1WKZ A;  2PS6 A;  4F6V A;  5EAU A;  5I1U A;  3WCA A;  3ICN A;  3WCL A;  2F8C F;  5IM1 A;  5IK6 A;  4MC3 A;  4LZ0 A;  1WL1 A;  2ONG A;  4RXE A;  5B0K A;  2Z4V A;  3AQC B;  3NPK A;  4N1Z F;  4WK5 A;  3P5R A;  3SDT A;  3WCG A;  3VJ9 A;  5DJR F;  5DW7 A;  3PH7 A;  3P8R A;  2E8W A;  2QIS A;  3ACX A;  1N1B A;  4MC0 A;  4XQT F;  2E8V A;  3KRO B;  5IL3 A;  2AEK A;  3P8L A;  4KWD A;  4KVI A;  4LFE A;  2AZL A;  2EWG A;  4OGU A;  3N3D A;  2E91 A;  5DHK A;  3N6K F;  3VJB A;  1HX9 A;  3N1V F;  3ASX A;  4GP2 A;  2E92 A;  3ID0 A;  3S9V A;  4N9U A;  1V4J A;  3TS7 A;  5IKH A;  2Z4X A;  4LXW A;  5HNA A;  2ZCO A;  3WCB A;  1VG3 A;  2Z50 A;  4KFA A;  3WEG A;  3MZV A;  2Q80 A;  5B0J A;  3N46 F;  4KUX A;  5ILZ A;  2F92 F;  3AQB B;  5B0M A;  5ERM A;  4KVY A;  4XQS F;  3M02 A;  4GA3 A;  2E8T A;  2PS5 A;  2I19 A;  3M01 A;  4NFJ F;  4XQR F;  3LJI A;  4JXY A;  2OPM A;  2Q58 A;  5E8K A;  2Z4Y A;  5DJP F;  3PYA A;  4LOB A;  5JV2 F;  1WL3 A;  3S4J A;  4KQ5 A;  2ONH A;  3OAB A;  4LA5 A;  1N1Z A;  2E8X A;  1YQ7 A; 
#chains in the Genus database with same CATH homology
 4H5D F;  4RNQ A;  3WE9 A;  3ZL6 A;  3LSN A;  4RXC A;  1KIZ A;  4JVJ F;  4LPG F;  3LOM A;  3ICK A;  3KRA A;  3WCH A;  4DWG A;  5B01 A;  4E1E A;  3KRF A;  3MAV A;  3N5J F;  2Z4W A;  1HM4 A;  4RYP A;  4OKM A;  4NKE A;  3OYR A;  5HN9 A;  4P0X A;  3SAE A;  1N22 A;  4LZ3 A;  3PDE A;  3SDR A;  1YYT A;  5JA0 F;  3WCD A;  1VG6 A;  3V1V A;  4K10 A;  3SDU A;  3WEF A;  3PYB A;  3LMD A;  1EZF A;  3B7L A;  4OMH A;  2PS7 A;  3N5H F;  3TFN A;  3G4D A;  2Z7H A;  3N0F A;  4KVW A;  3RBM A;  3WCM A;  4EA2 A;  3LG5 A;  3WCF A;  5A0K A;  5DGN F;  1RTR A;  1VG2 A;  4DEM F;  2Z4Z A;  2VF6 A;  5JV1 F;  3OAB B;  5ILJ A;  2OA6 A;  1YYR A;  3N49 F;  3SDQ A;  4H5E F;  1UBV A;  2ZCQ A;  1UBX A;  4KPD A;  3KRA B;  5DIQ F;  3BNX A;  5IL8 A;  4NFK F;  3KRF B;  1RQI A;  4RXD A;  5H9D A;  3VJ8 A;  5AEL A;  4E9U A;  3V1X A;  4JXN A;  3IPI A;  1V4E A;  1DGP A;  2OGD A;  2F94 F;  5B0L A;  4P0V A;  2ZY1 A;  5DGS F;  3NF2 A;  5IK9 A;  5ERO A;  5IN8 A;  3OAC B;  5E8H A;  3TC1 A;  3P5P A;  2E4O A;  3V66 A;  4E9Z A;  4LLT A;  3Q2Z A;  2FTZ A;  3ADZ A;  2E93 A;  5ER8 A;  3CC9 A;  3APZ A;  3G4F A;  3M00 A;  4ZQ8 A;  5JV0 F;  3KB9 A;  3Q2Q A;  3LVS A;  3PKO A;  1DI1 A;  1FPS A;  1WY0 A;  4PVX F;  4FJQ A;  3M9U A;  1KIY A;  5AFX A;  2H8O A;  1YYU A;  3ACW A;  3EGT A;  5EAT A;  5IK0 A;  2AZJ A;  4DHD A;  1PS1 A;  3ZMB A;  4LIX A;  2J1P A;  3N45 F;  2Z7I A;  4NKF A;  1UBW A;  4KPJ A;  3WSA A;  3WEJ A;  5ILK A;  3ACY A;  4RXA A;  1YJ4 A;  3VJA A;  3WSB A;  3WJO A;  2AZK A;  3WCC A;  3DYF A;  5B03 A;  3CKE A;  3QQV A;  1JFG A;  1HXA A;  2E8U A;  2RAH A;  5ILY A;  1YHM A;  3WEH A;  3WCJ A;  2Z52 A;  5AHU B;  4LPH F;  1N20 A;  5AYP A;  3SDV A;  5HN8 A;  4JZB A;  3Q30 A;  5ILH A;  3LLW A;  1V4I A;  1HM7 A;  5KSX F;  4QXS F;  3N1W F;  3RYE A;  5IMI A;  2E95 A;  5DZ2 A;  2Q9Z A;  3N0G A;  4EA1 A;  4NUA A;  3OAC A;  1RQJ A;  3DYG A;  3NPR A;  1N21 A;  3AQ0 A;  3KRC A;  5HN7 A;  3WEK A;  1YHL A;  5A0J A;  3EZ3 A;  3RYW A;  3N3L F;  2F7M F;  3AE0 A;  4KQU A;  3Q1O A;  1VG4 A;  3KRP A;  4KK2 A;  1YYS A;  4P0W A;  3W7F A;  5B02 A;  2AET A;  3LGZ B;  4H5C F;  4NFI F;  4DZW A;  3ICM A;  4LFG A;  5IMN A;  4F62 A;  4LA6 A;  3WEI A;  5IMP A;  2PS4 A;  4KVD A;  2F89 F;  2F8Z F;  1HXC A;  4LFV F;  3RMG A;  3VJC A;  3DYH A;  2J5C A;  5CG5 A;  4LTZ A;  3ZMC A;  4OMG A;  3UCA A;  3P41 A;  3KBK A;  3CP6 A;  4DI5 A;  3ZCD A;  4LUU A;  2OPN A;  5A0I A;  3KRC B;  2AEL A;  4LZC A;  1N23 A;  4EA0 A;  3QKC A;  4UMJ A;  5CG6 A;  5EAS A;  3WCE A;  4JZX A;  4PVY F;  5DHI A;  3KRP B;  1YYQ A;  3EFQ A;  3WCI A;  4DXJ A;  3M0G A;  1ZW5 A;  2FOR A;  3LK5 A;  3NRI A;  3LZ9 A;  4FP4 A;  3ICZ A;  3VJE A;  2ZCR A;  2ZEV A;  3WJN A;  2F9K F;  3LGK A;  4LTV A;  1YHK A;  4Q23 A;  4GP1 A;  1YV5 A;  3ZOU A;  2ZEU A;  5E8L A;  3VJD A;  1V4K A;  2P1C A;  3LDW A;  1WMW A;  4NG6 A;  4LLS A;  5ILI A;  5DJV F;  1WL0 A;  5B00 A;  2J1O A;  5C05 A;  2ZCS A;  3TFP A;  4GAX A;  4JYX A;  4F6X A;  3BNY A;  2PS8 A;  1UBY A;  5IVG A;  2E94 A;  5ERN A;  5JUZ F;  4MC8 A;  4OKZ A;  3WC9 A;  5ILD A;  1V4H A;  3TFV A;  2E90 A;  3KRO A;  2Z78 A;  3LEE A;  1N24 A;  1JFA A;  2O1O A;  2Q9Y A;  5DGM F;  1VG7 A;  1WL2 A;  1HXG A;  4KKM A;  4DWB A;  4KQS A;  4L2X F;  5IKA A;  3IBA A;  2DH4 A;  4HD1 A;  4QPF A;  3WJK A;  5B0I A;  1WKZ A;  2PS6 A;  4F6V A;  5EAU A;  5I1U A;  3WCA A;  3ICN A;  3WCL A;  2F8C F;  5IM1 A;  5IK6 A;  4MC3 A;  4LZ0 A;  1WL1 A;  2ONG A;  4RXE A;  5B0K A;  2Z4V A;  3AQC B;  3NPK A;  4N1Z F;  4WK5 A;  3P5R A;  3SDT A;  3WCG A;  3VJ9 A;  5DJR F;  5DW7 A;  3PH7 A;  3P8R A;  2E8W A;  2QIS A;  3ACX A;  1N1B A;  4MC0 A;  4XQT F;  2E8V A;  3KRO B;  5IL3 A;  2AEK A;  3P8L A;  4KWD A;  4KVI A;  4LFE A;  2AZL A;  2EWG A;  4OGU A;  3N3D A;  2E91 A;  5DHK A;  3N6K F;  3VJB A;  1HX9 A;  3N1V F;  3ASX A;  4GP2 A;  2E92 A;  3ID0 A;  3S9V A;  4N9U A;  1V4J A;  3TS7 A;  5IKH A;  2Z4X A;  4LXW A;  5HNA A;  2ZCO A;  3WCB A;  1VG3 A;  2Z50 A;  4KFA A;  3WEG A;  3MZV A;  2Q80 A;  5B0J A;  3N46 F;  4KUX A;  5ILZ A;  2F92 F;  3AQB B;  5B0M A;  5ERM A;  4KVY A;  4XQS F;  3M02 A;  4GA3 A;  2E8T A;  2PS5 A;  2I19 A;  3M01 A;  4NFJ F;  4XQR F;  3LJI A;  4JXY A;  2OPM A;  2Q58 A;  5E8K A;  2Z4Y A;  5DJP F;  3PYA A;  4LOB A;  5JV2 F;  1WL3 A;  3S4J A;  4KQ5 A;  2ONH A;  3OAB A;  4LA5 A;  1N1Z A;  2E8X A;  1YQ7 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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