4KQUA

Crystal structure of farnesyl synthase mutant (y204a) complexed with mg, alendronate and isopentenyl pyrophosphate
Total Genus 130
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
130
sequence length
344
structure length
340
Chain Sequence
YAQEKQDFVQHFSQIVRVLTEHPEIGDAIARLKEVLEYNAIGGKYNRGLTVVVAFRELVEPRKQDADSLQRAWTVGWCVELLQAFFLVADDIMDSSLTRRGQICWYQKPGVGLDAINDANLLEACIYRLLKLYCREQPYYLNLIELFLQSSYQTEIGQTLDLLTAPQGNVDLVRFTEKRYKSIVKYKTAFASFYLPIAAAMYMAGIDGEKEHANAKKILLEMGEFFQIQDDYLDLFGDPSVTGKIGTDIQDNKCSWLVVQCLQRATPEQYQILKENYGQKEAEKVARVKALYEELDLPAVFLQYEEDSYSHIMALIEQYAAPLPPAVFLGLARKIYKRRK
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal Structure of Farnesyl Synthase Mutant (Y204A) Complexed with Mg, Alendronate and Isopentenyl Pyrophosphate
rcsb
molecule tags Transferase
source organism Homo sapiens
molecule keywords Farnesyl pyrophosphate synthase
total genus 130
structure length 340
sequence length 344
ec nomenclature ec 2.5.1.1: Dimethylallyltranstransferase.
pdb deposition date 2013-05-15

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00348 polyprenyl_synt Polyprenyl synthetase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.600.10 Mainly Alpha Orthogonal Bundle Farnesyl Diphosphate Synthase Farnesyl Diphosphate Synthase 4kquA00
4RXAA 4QPFA 4H5EF 1HXAA 4MC8A 3ACYA 2E4OA 1PS1A 1N1BA 4DHDA 1JFGA 4Q23A 4NFKF 5CG5A 1YYQA 1UBYA 1VG3A 3LLWA 1UBWA 1VG2A 3Q1OA 5IKAA 3KRPA 3KRFB 5IL3A 3ZL6A 4PVXF 5JV2F 5AFXA 3S4JA 4DXJA 1UBXA 2E91A 4HD1A 2E90A 1N24A 3DYHA 5B0IA 2PS6A 3N46F 3LJIA 5B00A 4KFAA 2QISA 1N1ZA 3WEJA 5JUZF 3ACXA 4OKMA 3EZ3A 5A0KA 4PVYF 2E8WA 2PS5A 2E94A 4DI5A 2PS8A 4K10A 4EA0A 5B0LA 3OABB 4E1EA 1N22A 3S9VA 2ZEVA 4LA5A 2F8ZF 4FJQA 1V4HA 3RBMA 1HXCA 3PKOA 5H9DA 5IK6A 5A0JA 3QKCA 4N9UA 1WL3A 2Z4VA 3IBAA 5IKHA 3P5RA 3TFPA 1EZFA 4JXYA 1YYTA 3WEFA 4LPHF 1WL2A 4LZCA 5C05A 3AQ0A 3Q2QA 4JZBA 3WCGA 2OGDA 5AYPA 3VJCA 3IPIA 2F89F 5ILHA 3MAVA 3ZMCA 2F7MF 5E8LA 3KRFA 3LK5A 2ZCOA 4E9UA 4LOBA 4NUAA 2J5CA 3ZCDA 5IL8A 3LGKA 3VJ9A 4LFGA 5IN8A 5JA0F 4LLTA 2ZY1A 4E9ZA 3LDWA 5IK0A 4DZWA 1DGPA 4QXSF 4H5DF 2Z50A 3N49F 3WCDA 4L2XF 4JVJF 5DW7A 4EA2A 1V4IA 3AE0A 5ILDA 4P0XA 3WCFA 3OABA 3KRAA 3DYGA 3AQCB 4JXNA 3TC1A 3ZOUA 5DGMF 3N6KF 2Z78A 4GA3A 4UMJA 3WCLA 5A0IA 4P0WA 2P1CA 1RTRA 4KVYA 4NFJF 3WJKA 2ZEUA 5DJVF 1WL0A 3VJ8A 4OMHA 4RYPA 1V4KA 1YYRA 5DHKA 3LVSA 3KBKA 2Z7HA 5I1UA 4JZXA 3WCBA 3PYBA 1YYSA 5JV0F 3OACB 5CG6A 5JV1F 4OGUA 4RXCA 3VJEA 3W7FA 4OKZA 3CC9A 3WEKA 5ERMA 2OA6A 2Z4ZA 3WEGA 5HN8A 5ILZA 3RYEA 3WCIA 3G4FA 5DJPF 3ZMBA 3ADZA 3WSBA 1N23A 1YV5A 5IM1A 2OPMA 3Q2ZA 4KVWA 3WC9A 4F62A 4NKFA 2Z4XA 1HM4A 3ICKA 4GAXA 2I19A 3G4DA 5ILJA 5HN9A 2DH4A 1N21A 3WCAA 3KRAB 1DI1A 2Z4WA 4KPJA 4XQSF 3V1XA 3CP6A 1ZW5A 4KWDA 3P41A 1N20A 4KVIA 3LG5A 2Q58A 3WCEA 3WJNA 5E8HA 4F6XA 2Q9ZA 3SDRA 5DGSF 3VJDA 3Q30A 2E8UA 3PYAA 3B7LA 4GP1A 4LZ3A 4XQTF 4NFIF 3TFVA 4NG6A 5DZ2A 5DJRF 3DYFA 2VF6A 5DIQF 2FORA 4ZQ8A 4JYXA 5IK9A 5B0JA 4LTVA 5DGNF 3NPKA 3ASXA 4LIXA 3KROA 3OACA 3TS7A 2PS4A 3WSAA 3N0FA 4DWBA 3SDUA 2RAHA 1WY0A 2ZCQA 4KK2A 2OPNA 3N1WF 1YHMA 4RXDA 3RMGA 1UBVA 2E92A 2EWGA 3ICMA 3V66A 3LOMA 4LFVF 3N3DA 3OYRA 1FPSA 2Q9YA 3WCCA 1RQIA 3TFNA 3M0GA 3KRCA 2AZKA 1VG4A 3ACWA 2Z7IA 3WE9A 4KUXA 4MC0A 3LSNA 1YJ4A 3LEEA 2AEKA 5DHIA 1WMWA 3ICNA 3PH7A 1YHKA 5AHUB 3N45F 2FTZA 3NF2A 3P5PA 2AZJA 3KROB 3M00A 1VG6A 3M9UA 3CKEA 3N0GA 3WCJA 3BNXA 5KSXF 3LZ9A 4N1ZF 2F8CF 3V1VA 2E95A 5ER8A 3NRIA 4LLSA 2ZCSA 2F92F 2AETA 2F94F 5B02A 2Q80A 1KIZA 3SDTA 1KIYA 4KVDA 4FP4A 3N3LF 3EFQA 3SDQA 5EROA 3NPRA 4EA1A 2E8VA 3LMDA 3SAEA 4RNQA 3KRCB 4LXWA 4RXEA 4KQSA 4LZ0A 1HXGA 3AQBB 5EAUA 2E8TA 1VG7A 4LPGF 3WCHA 3MZVA 5IVGA 5HN7A 3P8LA 4XQRF 5E8KA 3EGTA 2E8XA 4LUUA 1JFAA 1HM7A 4LTZA 4WK5A 5IMNA 4DEMF 3M02A 4LFEA 4KQ5A 4MC3A 1V4JA 3M01A 3RYWA 2F9KF 2ZCRA 1YQ7A 1V4EA 5HNAA 4DWGA 5ILYA 3UCAA 4H5CF 3WEHA 1RQJA 5B03A 3KRPB 1WL1A 2O1OA 3VJAA 1YHLA 5IMIA 1WKZA 2ONGA 3BNYA 3N1VF 4NKEA 4KQUA 3WJOA 2Z52A 5ILKA 1HX9A 3WCMA 3N5JF 5B0KA 3KB9A 3VJBA 3N5HF 2PS7A 3PDEA 4LA6A 5IMPA 4F6VA 2J1OA 4OMGA 3WEIA 2H8OA 2E93A 1YYUA 3LGZB 3P8RA 2ONHA 3ID0A 5ERNA 3SDVA 5AELA 2Z4YA 3APZA 5EATA 4P0VA 3QQVA 4KPDA 2AELA 4GP2A 4KKMA 2J1PA 2AZLA 5B01A 5EASA 3ICZA 5B0MA 5ILIA
chains in the Genus database with same CATH superfamily
4RXAA 4QPFA 4H5EF 1HXAA 4MC8A 3ACYA 2E4OA 1PS1A 1N1BA 4DHDA 1JFGA 4Q23A 4NFKF 5CG5A 1YYQA 1UBYA 1VG3A 3LLWA 1UBWA 1VG2A 3Q1OA 5IKAA 3KRPA 3KRFB 5IL3A 3ZL6A 4PVXF 5JV2F 5AFXA 3S4JA 4DXJA 1UBXA 2E91A 4HD1A 2E90A 1N24A 3DYHA 5B0IA 2PS6A 3N46F 3LJIA 5B00A 4KFAA 2QISA 1N1ZA 3WEJA 5JUZF 3ACXA 4OKMA 3EZ3A 5A0KA 4PVYF 2E8WA 2PS5A 2E94A 4DI5A 2PS8A 4K10A 4EA0A 5B0LA 3OABB 4E1EA 1N22A 3S9VA 2ZEVA 4LA5A 2F8ZF 4FJQA 1V4HA 3RBMA 1HXCA 3PKOA 5H9DA 5IK6A 5A0JA 3QKCA 4N9UA 1WL3A 2Z4VA 3IBAA 5IKHA 3P5RA 3TFPA 1EZFA 4JXYA 1YYTA 3WEFA 4LPHF 1WL2A 4LZCA 5C05A 3AQ0A 3Q2QA 4JZBA 3WCGA 2OGDA 5AYPA 3VJCA 3IPIA 2F89F 5ILHA 3MAVA 3ZMCA 2F7MF 5E8LA 3KRFA 3LK5A 2ZCOA 4E9UA 4LOBA 4NUAA 2J5CA 3ZCDA 5IL8A 3LGKA 3VJ9A 4LFGA 5IN8A 5JA0F 4LLTA 2ZY1A 4E9ZA 3LDWA 5IK0A 4DZWA 1DGPA 4QXSF 4H5DF 2Z50A 3N49F 3WCDA 4L2XF 4JVJF 5DW7A 4EA2A 1V4IA 3AE0A 5ILDA 4P0XA 3WCFA 3OABA 3KRAA 3DYGA 3AQCB 4JXNA 3TC1A 3ZOUA 5DGMF 3N6KF 2Z78A 4GA3A 4UMJA 3WCLA 5A0IA 4P0WA 2P1CA 1RTRA 4KVYA 4NFJF 3WJKA 2ZEUA 5DJVF 1WL0A 3VJ8A 4OMHA 4RYPA 1V4KA 1YYRA 5DHKA 3LVSA 3KBKA 2Z7HA 5I1UA 4JZXA 3WCBA 3PYBA 1YYSA 5JV0F 3OACB 5CG6A 5JV1F 4OGUA 4RXCA 3VJEA 3W7FA 4OKZA 3CC9A 3WEKA 5ERMA 2OA6A 2Z4ZA 3WEGA 5HN8A 5ILZA 3RYEA 3WCIA 3G4FA 5DJPF 3ZMBA 3ADZA 3WSBA 1N23A 1YV5A 5IM1A 2OPMA 3Q2ZA 4KVWA 3WC9A 4F62A 4NKFA 2Z4XA 1HM4A 3ICKA 4GAXA 2I19A 3G4DA 5ILJA 5HN9A 2DH4A 1N21A 3WCAA 3KRAB 1DI1A 2Z4WA 4KPJA 4XQSF 3V1XA 3CP6A 1ZW5A 4KWDA 3P41A 1N20A 4KVIA 3LG5A 2Q58A 3WCEA 3WJNA 5E8HA 4F6XA 2Q9ZA 3SDRA 5DGSF 3VJDA 3Q30A 2E8UA 3PYAA 3B7LA 4GP1A 4LZ3A 4XQTF 4NFIF 3TFVA 4NG6A 5DZ2A 5DJRF 3DYFA 2VF6A 5DIQF 2FORA 4ZQ8A 4JYXA 5IK9A 5B0JA 4LTVA 5DGNF 3NPKA 3ASXA 4LIXA 3KROA 3OACA 3TS7A 2PS4A 3WSAA 3N0FA 4DWBA 3SDUA 2RAHA 1WY0A 2ZCQA 4KK2A 2OPNA 3N1WF 1YHMA 4RXDA 3RMGA 1UBVA 2E92A 2EWGA 3ICMA 3V66A 3LOMA 4LFVF 3N3DA 3OYRA 1FPSA 2Q9YA 3WCCA 1RQIA 3TFNA 3M0GA 3KRCA 2AZKA 1VG4A 3ACWA 2Z7IA 3WE9A 4KUXA 4MC0A 3LSNA 1YJ4A 3LEEA 2AEKA 5DHIA 1WMWA 3ICNA 3PH7A 1YHKA 5AHUB 3N45F 2FTZA 3NF2A 3P5PA 2AZJA 3KROB 3M00A 1VG6A 3M9UA 3CKEA 3N0GA 3WCJA 3BNXA 5KSXF 3LZ9A 4N1ZF 2F8CF 3V1VA 2E95A 5ER8A 3NRIA 4LLSA 2ZCSA 2F92F 2AETA 2F94F 5B02A 2Q80A 1KIZA 3SDTA 1KIYA 4KVDA 4FP4A 3N3LF 3EFQA 3SDQA 5EROA 3NPRA 4EA1A 2E8VA 3LMDA 3SAEA 4RNQA 3KRCB 4LXWA 4RXEA 4KQSA 4LZ0A 1HXGA 3AQBB 5EAUA 2E8TA 1VG7A 4LPGF 3WCHA 3MZVA 5IVGA 5HN7A 3P8LA 4XQRF 5E8KA 3EGTA 2E8XA 4LUUA 1JFAA 1HM7A 4LTZA 4WK5A 5IMNA 4DEMF 3M02A 4LFEA 4KQ5A 4MC3A 1V4JA 3M01A 3RYWA 2F9KF 2ZCRA 1YQ7A 1V4EA 5HNAA 4DWGA 5ILYA 3UCAA 4H5CF 3WEHA 1RQJA 5B03A 3KRPB 1WL1A 2O1OA 3VJAA 1YHLA 5IMIA 1WKZA 2ONGA 3BNYA 3N1VF 4NKEA 4KQUA 3WJOA 2Z52A 5ILKA 1HX9A 3WCMA 3N5JF 5B0KA 3KB9A 3VJBA 3N5HF 2PS7A 3PDEA 4LA6A 5IMPA 4F6VA 2J1OA 4OMGA 3WEIA 2H8OA 2E93A 1YYUA 3LGZB 3P8RA 2ONHA 3ID0A 5ERNA 3SDVA 5AELA 2Z4YA 3APZA 5EATA 4P0VA 3QQVA 4KPDA 2AELA 4GP2A 4KKMA 2J1PA 2AZLA 5B01A 5EASA 3ICZA 5B0MA 5ILIA
chains in the Genus database with same CATH topology
4RXAA 4QPFA 4H5EF 1HXAA 4MC8A 3ACYA 2E4OA 1PS1A 1N1BA 4DHDA 1JFGA 4Q23A 4NFKF 5CG5A 1YYQA 1UBYA 1VG3A 3LLWA 1UBWA 1VG2A 3Q1OA 5IKAA 3KRPA 3KRFB 5IL3A 3ZL6A 4PVXF 5JV2F 5AFXA 3S4JA 4DXJA 1UBXA 2E91A 4HD1A 2E90A 1N24A 3DYHA 5B0IA 2PS6A 3N46F 3LJIA 5B00A 4KFAA 2QISA 1N1ZA 3WEJA 5JUZF 3ACXA 4OKMA 3EZ3A 5A0KA 4PVYF 2E8WA 2PS5A 2E94A 4DI5A 2PS8A 4K10A 4EA0A 5B0LA 3OABB 4E1EA 1N22A 3S9VA 2ZEVA 4LA5A 2F8ZF 4FJQA 1V4HA 3RBMA 1HXCA 3PKOA 5H9DA 5IK6A 5A0JA 3QKCA 4N9UA 1WL3A 2Z4VA 3IBAA 5IKHA 3P5RA 3TFPA 1EZFA 4JXYA 1YYTA 3WEFA 4LPHF 1WL2A 4LZCA 5C05A 3AQ0A 3Q2QA 4JZBA 3WCGA 2OGDA 5AYPA 3VJCA 3IPIA 2F89F 5ILHA 3MAVA 3ZMCA 2F7MF 5E8LA 3KRFA 3LK5A 2ZCOA 4E9UA 4LOBA 4NUAA 2J5CA 3ZCDA 5IL8A 3LGKA 3VJ9A 4LFGA 5IN8A 5JA0F 4LLTA 2ZY1A 4E9ZA 3LDWA 5IK0A 4DZWA 1DGPA 4QXSF 4H5DF 2Z50A 3N49F 3WCDA 4L2XF 4JVJF 5DW7A 4EA2A 1V4IA 3AE0A 5ILDA 4P0XA 3WCFA 3OABA 3KRAA 3DYGA 3AQCB 4JXNA 3TC1A 3ZOUA 5DGMF 3N6KF 2Z78A 4GA3A 4UMJA 3WCLA 5A0IA 4P0WA 2P1CA 1RTRA 4KVYA 4NFJF 3WJKA 2ZEUA 5DJVF 1WL0A 3VJ8A 4OMHA 4RYPA 1V4KA 1YYRA 5DHKA 3LVSA 3KBKA 2Z7HA 5I1UA 4JZXA 3WCBA 3PYBA 1YYSA 5JV0F 3OACB 5CG6A 5JV1F 4OGUA 4RXCA 3VJEA 3W7FA 4OKZA 3CC9A 3WEKA 5ERMA 2OA6A 2Z4ZA 3WEGA 5HN8A 5ILZA 3RYEA 3WCIA 3G4FA 5DJPF 3ZMBA 3ADZA 3WSBA 1N23A 1YV5A 5IM1A 2OPMA 3Q2ZA 4KVWA 3WC9A 4F62A 4NKFA 2Z4XA 1HM4A 3ICKA 4GAXA 2I19A 3G4DA 5ILJA 5HN9A 2DH4A 1N21A 3WCAA 3KRAB 1DI1A 2Z4WA 4KPJA 4XQSF 3V1XA 3CP6A 1ZW5A 4KWDA 3P41A 1N20A 4KVIA 3LG5A 2Q58A 3WCEA 3WJNA 5E8HA 4F6XA 2Q9ZA 3SDRA 5DGSF 3VJDA 3Q30A 2E8UA 3PYAA 3B7LA 4GP1A 4LZ3A 4XQTF 4NFIF 3TFVA 4NG6A 5DZ2A 5DJRF 3DYFA 2VF6A 5DIQF 2FORA 4ZQ8A 4JYXA 5IK9A 5B0JA 4LTVA 5DGNF 3NPKA 3ASXA 4LIXA 3KROA 3OACA 3TS7A 2PS4A 3WSAA 3N0FA 4DWBA 3SDUA 2RAHA 1WY0A 2ZCQA 4KK2A 2OPNA 3N1WF 1YHMA 4RXDA 3RMGA 1UBVA 2E92A 2EWGA 3ICMA 3V66A 3LOMA 4LFVF 3N3DA 3OYRA 1FPSA 2Q9YA 3WCCA 1RQIA 3TFNA 3M0GA 3KRCA 2AZKA 1VG4A 3ACWA 2Z7IA 3WE9A 4KUXA 4MC0A 3LSNA 1YJ4A 3LEEA 2AEKA 5DHIA 1WMWA 3ICNA 3PH7A 1YHKA 5AHUB 3N45F 2FTZA 3NF2A 3P5PA 2AZJA 3KROB 3M00A 1VG6A 3M9UA 3CKEA 3N0GA 3WCJA 3BNXA 5KSXF 3LZ9A 4N1ZF 2F8CF 3V1VA 2E95A 5ER8A 3NRIA 4LLSA 2ZCSA 2F92F 2AETA 2F94F 5B02A 2Q80A 1KIZA 3SDTA 1KIYA 4KVDA 4FP4A 3N3LF 3EFQA 3SDQA 5EROA 3NPRA 4EA1A 2E8VA 3LMDA 3SAEA 4RNQA 3KRCB 4LXWA 4RXEA 4KQSA 4LZ0A 1HXGA 3AQBB 5EAUA 2E8TA 1VG7A 4LPGF 3WCHA 3MZVA 5IVGA 5HN7A 3P8LA 4XQRF 5E8KA 3EGTA 2E8XA 4LUUA 1JFAA 1HM7A 4LTZA 4WK5A 5IMNA 4DEMF 3M02A 4LFEA 4KQ5A 4MC3A 1V4JA 3M01A 3RYWA 2F9KF 2ZCRA 1YQ7A 1V4EA 5HNAA 4DWGA 5ILYA 3UCAA 4H5CF 3WEHA 1RQJA 5B03A 3KRPB 1WL1A 2O1OA 3VJAA 1YHLA 5IMIA 1WKZA 2ONGA 3BNYA 3N1VF 4NKEA 4KQUA 3WJOA 2Z52A 5ILKA 1HX9A 3WCMA 3N5JF 5B0KA 3KB9A 3VJBA 3N5HF 2PS7A 3PDEA 4LA6A 5IMPA 4F6VA 2J1OA 4OMGA 3WEIA 2H8OA 2E93A 1YYUA 3LGZB 3P8RA 2ONHA 3ID0A 5ERNA 3SDVA 5AELA 2Z4YA 3APZA 5EATA 4P0VA 3QQVA 4KPDA 2AELA 4GP2A 4KKMA 2J1PA 2AZLA 5B01A 5EASA 3ICZA 5B0MA 5ILIA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4RXA A;  4QPF A;  4H5E F;  1HXA A;  4MC8 A;  3ACY A;  2E4O A;  1PS1 A;  1N1B A;  4DHD A;  1JFG A;  4Q23 A;  4NFK F;  5CG5 A;  1YYQ A;  1UBY A;  1VG3 A;  3LLW A;  1UBW A;  1VG2 A;  3Q1O A;  5IKA A;  3KRP A;  3KRF B;  5IL3 A;  3ZL6 A;  4PVX F;  5JV2 F;  5AFX A;  3S4J A;  4DXJ A;  1UBX A;  2E91 A;  4HD1 A;  2E90 A;  1N24 A;  3DYH A;  5B0I A;  2PS6 A;  3N46 F;  3LJI A;  5B00 A;  4KFA A;  2QIS A;  1N1Z A;  3WEJ A;  5JUZ F;  3ACX A;  4OKM A;  3EZ3 A;  5A0K A;  4PVY F;  2E8W A;  2PS5 A;  2E94 A;  4DI5 A;  2PS8 A;  4K10 A;  4EA0 A;  5B0L A;  3OAB B;  4E1E A;  1N22 A;  3S9V A;  2ZEV A;  4LA5 A;  2F8Z F;  4FJQ A;  1V4H A;  3RBM A;  1HXC A;  3PKO A;  5H9D A;  5IK6 A;  5A0J A;  3QKC A;  4N9U A;  1WL3 A;  2Z4V A;  3IBA A;  5IKH A;  3P5R A;  3TFP A;  1EZF A;  4JXY A;  1YYT A;  3WEF A;  4LPH F;  1WL2 A;  4LZC A;  5C05 A;  3AQ0 A;  3Q2Q A;  4JZB A;  3WCG A;  2OGD A;  5AYP A;  3VJC A;  3IPI A;  2F89 F;  5ILH A;  3MAV A;  3ZMC A;  2F7M F;  5E8L A;  3KRF A;  3LK5 A;  2ZCO A;  4E9U A;  4LOB A;  4NUA A;  2J5C A;  3ZCD A;  5IL8 A;  3LGK A;  3VJ9 A;  4LFG A;  5IN8 A;  5JA0 F;  4LLT A;  2ZY1 A;  4E9Z A;  3LDW A;  5IK0 A;  4DZW A;  1DGP A;  4QXS F;  4H5D F;  2Z50 A;  3N49 F;  3WCD A;  4L2X F;  4JVJ F;  5DW7 A;  4EA2 A;  1V4I A;  3AE0 A;  5ILD A;  4P0X A;  3WCF A;  3OAB A;  3KRA A;  3DYG A;  3AQC B;  4JXN A;  3TC1 A;  3ZOU A;  5DGM F;  3N6K F;  2Z78 A;  4GA3 A;  4UMJ A;  3WCL A;  5A0I A;  4P0W A;  2P1C A;  1RTR A;  4KVY A;  4NFJ F;  3WJK A;  2ZEU A;  5DJV F;  1WL0 A;  3VJ8 A;  4OMH A;  4RYP A;  1V4K A;  1YYR A;  5DHK A;  3LVS A;  3KBK A;  2Z7H A;  5I1U A;  4JZX A;  3WCB A;  3PYB A;  1YYS A;  5JV0 F;  3OAC B;  5CG6 A;  5JV1 F;  4OGU A;  4RXC A;  3VJE A;  3W7F A;  4OKZ A;  3CC9 A;  3WEK A;  5ERM A;  2OA6 A;  2Z4Z A;  3WEG A;  5HN8 A;  5ILZ A;  3RYE A;  3WCI A;  3G4F A;  5DJP F;  3ZMB A;  3ADZ A;  3WSB A;  1N23 A;  1YV5 A;  5IM1 A;  2OPM A;  3Q2Z A;  4KVW A;  3WC9 A;  4F62 A;  4NKF A;  2Z4X A;  1HM4 A;  3ICK A;  4GAX A;  2I19 A;  3G4D A;  5ILJ A;  5HN9 A;  2DH4 A;  1N21 A;  3WCA A;  3KRA B;  1DI1 A;  2Z4W A;  4KPJ A;  4XQS F;  3V1X A;  3CP6 A;  1ZW5 A;  4KWD A;  3P41 A;  1N20 A;  4KVI A;  3LG5 A;  2Q58 A;  3WCE A;  3WJN A;  5E8H A;  4F6X A;  2Q9Z A;  3SDR A;  5DGS F;  3VJD A;  3Q30 A;  2E8U A;  3PYA A;  3B7L A;  4GP1 A;  4LZ3 A;  4XQT F;  4NFI F;  3TFV A;  4NG6 A;  5DZ2 A;  5DJR F;  3DYF A;  2VF6 A;  5DIQ F;  2FOR A;  4ZQ8 A;  4JYX A;  5IK9 A;  5B0J A;  4LTV A;  5DGN F;  3NPK A;  3ASX A;  4LIX A;  3KRO A;  3OAC A;  3TS7 A;  2PS4 A;  3WSA A;  3N0F A;  4DWB A;  3SDU A;  2RAH A;  1WY0 A;  2ZCQ A;  4KK2 A;  2OPN A;  3N1W F;  1YHM A;  4RXD A;  3RMG A;  1UBV A;  2E92 A;  2EWG A;  3ICM A;  3V66 A;  3LOM A;  4LFV F;  3N3D A;  3OYR A;  1FPS A;  2Q9Y A;  3WCC A;  1RQI A;  3TFN A;  3M0G A;  3KRC A;  2AZK A;  1VG4 A;  3ACW A;  2Z7I A;  3WE9 A;  4KUX A;  4MC0 A;  3LSN A;  1YJ4 A;  3LEE A;  2AEK A;  5DHI A;  1WMW A;  3ICN A;  3PH7 A;  1YHK A;  5AHU B;  3N45 F;  2FTZ A;  3NF2 A;  3P5P A;  2AZJ A;  3KRO B;  3M00 A;  1VG6 A;  3M9U A;  3CKE A;  3N0G A;  3WCJ A;  3BNX A;  5KSX F;  3LZ9 A;  4N1Z F;  2F8C F;  3V1V A;  2E95 A;  5ER8 A;  3NRI A;  4LLS A;  2ZCS A;  2F92 F;  2AET A;  2F94 F;  5B02 A;  2Q80 A;  1KIZ A;  3SDT A;  1KIY A;  4KVD A;  4FP4 A;  3N3L F;  3EFQ A;  3SDQ A;  5ERO A;  3NPR A;  4EA1 A;  2E8V A;  3LMD A;  3SAE A;  4RNQ A;  3KRC B;  4LXW A;  4RXE A;  4KQS A;  4LZ0 A;  1HXG A;  3AQB B;  5EAU A;  2E8T A;  1VG7 A;  4LPG F;  3WCH A;  3MZV A;  5IVG A;  5HN7 A;  3P8L A;  4XQR F;  5E8K A;  3EGT A;  2E8X A;  4LUU A;  1JFA A;  1HM7 A;  4LTZ A;  4WK5 A;  5IMN A;  4DEM F;  3M02 A;  4LFE A;  4KQ5 A;  4MC3 A;  1V4J A;  3M01 A;  3RYW A;  2F9K F;  2ZCR A;  1YQ7 A;  1V4E A;  5HNA A;  4DWG A;  5ILY A;  3UCA A;  4H5C F;  3WEH A;  1RQJ A;  5B03 A;  3KRP B;  1WL1 A;  2O1O A;  3VJA A;  1YHL A;  5IMI A;  1WKZ A;  2ONG A;  3BNY A;  3N1V F;  4NKE A;  4KQU A;  3WJO A;  2Z52 A;  5ILK A;  1HX9 A;  3WCM A;  3N5J F;  5B0K A;  3KB9 A;  3VJB A;  3N5H F;  2PS7 A;  3PDE A;  4LA6 A;  5IMP A;  4F6V A;  2J1O A;  4OMG A;  3WEI A;  2H8O A;  2E93 A;  1YYU A;  3LGZ B;  3P8R A;  2ONH A;  3ID0 A;  5ERN A;  3SDV A;  5AEL A;  2Z4Y A;  3APZ A;  5EAT A;  4P0V A;  3QQV A;  4KPD A;  2AEL A;  4GP2 A;  4KKM A;  2J1P A;  2AZL A;  5B01 A;  5EAS A;  3ICZ A;  5B0M A;  5ILI A; 
#chains in the Genus database with same CATH topology
 4RXA A;  4QPF A;  4H5E F;  1HXA A;  4MC8 A;  3ACY A;  2E4O A;  1PS1 A;  1N1B A;  4DHD A;  1JFG A;  4Q23 A;  4NFK F;  5CG5 A;  1YYQ A;  1UBY A;  1VG3 A;  3LLW A;  1UBW A;  1VG2 A;  3Q1O A;  5IKA A;  3KRP A;  3KRF B;  5IL3 A;  3ZL6 A;  4PVX F;  5JV2 F;  5AFX A;  3S4J A;  4DXJ A;  1UBX A;  2E91 A;  4HD1 A;  2E90 A;  1N24 A;  3DYH A;  5B0I A;  2PS6 A;  3N46 F;  3LJI A;  5B00 A;  4KFA A;  2QIS A;  1N1Z A;  3WEJ A;  5JUZ F;  3ACX A;  4OKM A;  3EZ3 A;  5A0K A;  4PVY F;  2E8W A;  2PS5 A;  2E94 A;  4DI5 A;  2PS8 A;  4K10 A;  4EA0 A;  5B0L A;  3OAB B;  4E1E A;  1N22 A;  3S9V A;  2ZEV A;  4LA5 A;  2F8Z F;  4FJQ A;  1V4H A;  3RBM A;  1HXC A;  3PKO A;  5H9D A;  5IK6 A;  5A0J A;  3QKC A;  4N9U A;  1WL3 A;  2Z4V A;  3IBA A;  5IKH A;  3P5R A;  3TFP A;  1EZF A;  4JXY A;  1YYT A;  3WEF A;  4LPH F;  1WL2 A;  4LZC A;  5C05 A;  3AQ0 A;  3Q2Q A;  4JZB A;  3WCG A;  2OGD A;  5AYP A;  3VJC A;  3IPI A;  2F89 F;  5ILH A;  3MAV A;  3ZMC A;  2F7M F;  5E8L A;  3KRF A;  3LK5 A;  2ZCO A;  4E9U A;  4LOB A;  4NUA A;  2J5C A;  3ZCD A;  5IL8 A;  3LGK A;  3VJ9 A;  4LFG A;  5IN8 A;  5JA0 F;  4LLT A;  2ZY1 A;  4E9Z A;  3LDW A;  5IK0 A;  4DZW A;  1DGP A;  4QXS F;  4H5D F;  2Z50 A;  3N49 F;  3WCD A;  4L2X F;  4JVJ F;  5DW7 A;  4EA2 A;  1V4I A;  3AE0 A;  5ILD A;  4P0X A;  3WCF A;  3OAB A;  3KRA A;  3DYG A;  3AQC B;  4JXN A;  3TC1 A;  3ZOU A;  5DGM F;  3N6K F;  2Z78 A;  4GA3 A;  4UMJ A;  3WCL A;  5A0I A;  4P0W A;  2P1C A;  1RTR A;  4KVY A;  4NFJ F;  3WJK A;  2ZEU A;  5DJV F;  1WL0 A;  3VJ8 A;  4OMH A;  4RYP A;  1V4K A;  1YYR A;  5DHK A;  3LVS A;  3KBK A;  2Z7H A;  5I1U A;  4JZX A;  3WCB A;  3PYB A;  1YYS A;  5JV0 F;  3OAC B;  5CG6 A;  5JV1 F;  4OGU A;  4RXC A;  3VJE A;  3W7F A;  4OKZ A;  3CC9 A;  3WEK A;  5ERM A;  2OA6 A;  2Z4Z A;  3WEG A;  5HN8 A;  5ILZ A;  3RYE A;  3WCI A;  3G4F A;  5DJP F;  3ZMB A;  3ADZ A;  3WSB A;  1N23 A;  1YV5 A;  5IM1 A;  2OPM A;  3Q2Z A;  4KVW A;  3WC9 A;  4F62 A;  4NKF A;  2Z4X A;  1HM4 A;  3ICK A;  4GAX A;  2I19 A;  3G4D A;  5ILJ A;  5HN9 A;  2DH4 A;  1N21 A;  3WCA A;  3KRA B;  1DI1 A;  2Z4W A;  4KPJ A;  4XQS F;  3V1X A;  3CP6 A;  1ZW5 A;  4KWD A;  3P41 A;  1N20 A;  4KVI A;  3LG5 A;  2Q58 A;  3WCE A;  3WJN A;  5E8H A;  4F6X A;  2Q9Z A;  3SDR A;  5DGS F;  3VJD A;  3Q30 A;  2E8U A;  3PYA A;  3B7L A;  4GP1 A;  4LZ3 A;  4XQT F;  4NFI F;  3TFV A;  4NG6 A;  5DZ2 A;  5DJR F;  3DYF A;  2VF6 A;  5DIQ F;  2FOR A;  4ZQ8 A;  4JYX A;  5IK9 A;  5B0J A;  4LTV A;  5DGN F;  3NPK A;  3ASX A;  4LIX A;  3KRO A;  3OAC A;  3TS7 A;  2PS4 A;  3WSA A;  3N0F A;  4DWB A;  3SDU A;  2RAH A;  1WY0 A;  2ZCQ A;  4KK2 A;  2OPN A;  3N1W F;  1YHM A;  4RXD A;  3RMG A;  1UBV A;  2E92 A;  2EWG A;  3ICM A;  3V66 A;  3LOM A;  4LFV F;  3N3D A;  3OYR A;  1FPS A;  2Q9Y A;  3WCC A;  1RQI A;  3TFN A;  3M0G A;  3KRC A;  2AZK A;  1VG4 A;  3ACW A;  2Z7I A;  3WE9 A;  4KUX A;  4MC0 A;  3LSN A;  1YJ4 A;  3LEE A;  2AEK A;  5DHI A;  1WMW A;  3ICN A;  3PH7 A;  1YHK A;  5AHU B;  3N45 F;  2FTZ A;  3NF2 A;  3P5P A;  2AZJ A;  3KRO B;  3M00 A;  1VG6 A;  3M9U A;  3CKE A;  3N0G A;  3WCJ A;  3BNX A;  5KSX F;  3LZ9 A;  4N1Z F;  2F8C F;  3V1V A;  2E95 A;  5ER8 A;  3NRI A;  4LLS A;  2ZCS A;  2F92 F;  2AET A;  2F94 F;  5B02 A;  2Q80 A;  1KIZ A;  3SDT A;  1KIY A;  4KVD A;  4FP4 A;  3N3L F;  3EFQ A;  3SDQ A;  5ERO A;  3NPR A;  4EA1 A;  2E8V A;  3LMD A;  3SAE A;  4RNQ A;  3KRC B;  4LXW A;  4RXE A;  4KQS A;  4LZ0 A;  1HXG A;  3AQB B;  5EAU A;  2E8T A;  1VG7 A;  4LPG F;  3WCH A;  3MZV A;  5IVG A;  5HN7 A;  3P8L A;  4XQR F;  5E8K A;  3EGT A;  2E8X A;  4LUU A;  1JFA A;  1HM7 A;  4LTZ A;  4WK5 A;  5IMN A;  4DEM F;  3M02 A;  4LFE A;  4KQ5 A;  4MC3 A;  1V4J A;  3M01 A;  3RYW A;  2F9K F;  2ZCR A;  1YQ7 A;  1V4E A;  5HNA A;  4DWG A;  5ILY A;  3UCA A;  4H5C F;  3WEH A;  1RQJ A;  5B03 A;  3KRP B;  1WL1 A;  2O1O A;  3VJA A;  1YHL A;  5IMI A;  1WKZ A;  2ONG A;  3BNY A;  3N1V F;  4NKE A;  4KQU A;  3WJO A;  2Z52 A;  5ILK A;  1HX9 A;  3WCM A;  3N5J F;  5B0K A;  3KB9 A;  3VJB A;  3N5H F;  2PS7 A;  3PDE A;  4LA6 A;  5IMP A;  4F6V A;  2J1O A;  4OMG A;  3WEI A;  2H8O A;  2E93 A;  1YYU A;  3LGZ B;  3P8R A;  2ONH A;  3ID0 A;  5ERN A;  3SDV A;  5AEL A;  2Z4Y A;  3APZ A;  5EAT A;  4P0V A;  3QQV A;  4KPD A;  2AEL A;  4GP2 A;  4KKM A;  2J1P A;  2AZL A;  5B01 A;  5EAS A;  3ICZ A;  5B0M A;  5ILI A; 
#chains in the Genus database with same CATH homology
 4RXA A;  4QPF A;  4H5E F;  1HXA A;  4MC8 A;  3ACY A;  2E4O A;  1PS1 A;  1N1B A;  4DHD A;  1JFG A;  4Q23 A;  4NFK F;  5CG5 A;  1YYQ A;  1UBY A;  1VG3 A;  3LLW A;  1UBW A;  1VG2 A;  3Q1O A;  5IKA A;  3KRP A;  3KRF B;  5IL3 A;  3ZL6 A;  4PVX F;  5JV2 F;  5AFX A;  3S4J A;  4DXJ A;  1UBX A;  2E91 A;  4HD1 A;  2E90 A;  1N24 A;  3DYH A;  5B0I A;  2PS6 A;  3N46 F;  3LJI A;  5B00 A;  4KFA A;  2QIS A;  1N1Z A;  3WEJ A;  5JUZ F;  3ACX A;  4OKM A;  3EZ3 A;  5A0K A;  4PVY F;  2E8W A;  2PS5 A;  2E94 A;  4DI5 A;  2PS8 A;  4K10 A;  4EA0 A;  5B0L A;  3OAB B;  4E1E A;  1N22 A;  3S9V A;  2ZEV A;  4LA5 A;  2F8Z F;  4FJQ A;  1V4H A;  3RBM A;  1HXC A;  3PKO A;  5H9D A;  5IK6 A;  5A0J A;  3QKC A;  4N9U A;  1WL3 A;  2Z4V A;  3IBA A;  5IKH A;  3P5R A;  3TFP A;  1EZF A;  4JXY A;  1YYT A;  3WEF A;  4LPH F;  1WL2 A;  4LZC A;  5C05 A;  3AQ0 A;  3Q2Q A;  4JZB A;  3WCG A;  2OGD A;  5AYP A;  3VJC A;  3IPI A;  2F89 F;  5ILH A;  3MAV A;  3ZMC A;  2F7M F;  5E8L A;  3KRF A;  3LK5 A;  2ZCO A;  4E9U A;  4LOB A;  4NUA A;  2J5C A;  3ZCD A;  5IL8 A;  3LGK A;  3VJ9 A;  4LFG A;  5IN8 A;  5JA0 F;  4LLT A;  2ZY1 A;  4E9Z A;  3LDW A;  5IK0 A;  4DZW A;  1DGP A;  4QXS F;  4H5D F;  2Z50 A;  3N49 F;  3WCD A;  4L2X F;  4JVJ F;  5DW7 A;  4EA2 A;  1V4I A;  3AE0 A;  5ILD A;  4P0X A;  3WCF A;  3OAB A;  3KRA A;  3DYG A;  3AQC B;  4JXN A;  3TC1 A;  3ZOU A;  5DGM F;  3N6K F;  2Z78 A;  4GA3 A;  4UMJ A;  3WCL A;  5A0I A;  4P0W A;  2P1C A;  1RTR A;  4KVY A;  4NFJ F;  3WJK A;  2ZEU A;  5DJV F;  1WL0 A;  3VJ8 A;  4OMH A;  4RYP A;  1V4K A;  1YYR A;  5DHK A;  3LVS A;  3KBK A;  2Z7H A;  5I1U A;  4JZX A;  3WCB A;  3PYB A;  1YYS A;  5JV0 F;  3OAC B;  5CG6 A;  5JV1 F;  4OGU A;  4RXC A;  3VJE A;  3W7F A;  4OKZ A;  3CC9 A;  3WEK A;  5ERM A;  2OA6 A;  2Z4Z A;  3WEG A;  5HN8 A;  5ILZ A;  3RYE A;  3WCI A;  3G4F A;  5DJP F;  3ZMB A;  3ADZ A;  3WSB A;  1N23 A;  1YV5 A;  5IM1 A;  2OPM A;  3Q2Z A;  4KVW A;  3WC9 A;  4F62 A;  4NKF A;  2Z4X A;  1HM4 A;  3ICK A;  4GAX A;  2I19 A;  3G4D A;  5ILJ A;  5HN9 A;  2DH4 A;  1N21 A;  3WCA A;  3KRA B;  1DI1 A;  2Z4W A;  4KPJ A;  4XQS F;  3V1X A;  3CP6 A;  1ZW5 A;  4KWD A;  3P41 A;  1N20 A;  4KVI A;  3LG5 A;  2Q58 A;  3WCE A;  3WJN A;  5E8H A;  4F6X A;  2Q9Z A;  3SDR A;  5DGS F;  3VJD A;  3Q30 A;  2E8U A;  3PYA A;  3B7L A;  4GP1 A;  4LZ3 A;  4XQT F;  4NFI F;  3TFV A;  4NG6 A;  5DZ2 A;  5DJR F;  3DYF A;  2VF6 A;  5DIQ F;  2FOR A;  4ZQ8 A;  4JYX A;  5IK9 A;  5B0J A;  4LTV A;  5DGN F;  3NPK A;  3ASX A;  4LIX A;  3KRO A;  3OAC A;  3TS7 A;  2PS4 A;  3WSA A;  3N0F A;  4DWB A;  3SDU A;  2RAH A;  1WY0 A;  2ZCQ A;  4KK2 A;  2OPN A;  3N1W F;  1YHM A;  4RXD A;  3RMG A;  1UBV A;  2E92 A;  2EWG A;  3ICM A;  3V66 A;  3LOM A;  4LFV F;  3N3D A;  3OYR A;  1FPS A;  2Q9Y A;  3WCC A;  1RQI A;  3TFN A;  3M0G A;  3KRC A;  2AZK A;  1VG4 A;  3ACW A;  2Z7I A;  3WE9 A;  4KUX A;  4MC0 A;  3LSN A;  1YJ4 A;  3LEE A;  2AEK A;  5DHI A;  1WMW A;  3ICN A;  3PH7 A;  1YHK A;  5AHU B;  3N45 F;  2FTZ A;  3NF2 A;  3P5P A;  2AZJ A;  3KRO B;  3M00 A;  1VG6 A;  3M9U A;  3CKE A;  3N0G A;  3WCJ A;  3BNX A;  5KSX F;  3LZ9 A;  4N1Z F;  2F8C F;  3V1V A;  2E95 A;  5ER8 A;  3NRI A;  4LLS A;  2ZCS A;  2F92 F;  2AET A;  2F94 F;  5B02 A;  2Q80 A;  1KIZ A;  3SDT A;  1KIY A;  4KVD A;  4FP4 A;  3N3L F;  3EFQ A;  3SDQ A;  5ERO A;  3NPR A;  4EA1 A;  2E8V A;  3LMD A;  3SAE A;  4RNQ A;  3KRC B;  4LXW A;  4RXE A;  4KQS A;  4LZ0 A;  1HXG A;  3AQB B;  5EAU A;  2E8T A;  1VG7 A;  4LPG F;  3WCH A;  3MZV A;  5IVG A;  5HN7 A;  3P8L A;  4XQR F;  5E8K A;  3EGT A;  2E8X A;  4LUU A;  1JFA A;  1HM7 A;  4LTZ A;  4WK5 A;  5IMN A;  4DEM F;  3M02 A;  4LFE A;  4KQ5 A;  4MC3 A;  1V4J A;  3M01 A;  3RYW A;  2F9K F;  2ZCR A;  1YQ7 A;  1V4E A;  5HNA A;  4DWG A;  5ILY A;  3UCA A;  4H5C F;  3WEH A;  1RQJ A;  5B03 A;  3KRP B;  1WL1 A;  2O1O A;  3VJA A;  1YHL A;  5IMI A;  1WKZ A;  2ONG A;  3BNY A;  3N1V F;  4NKE A;  4KQU A;  3WJO A;  2Z52 A;  5ILK A;  1HX9 A;  3WCM A;  3N5J F;  5B0K A;  3KB9 A;  3VJB A;  3N5H F;  2PS7 A;  3PDE A;  4LA6 A;  5IMP A;  4F6V A;  2J1O A;  4OMG A;  3WEI A;  2H8O A;  2E93 A;  1YYU A;  3LGZ B;  3P8R A;  2ONH A;  3ID0 A;  5ERN A;  3SDV A;  5AEL A;  2Z4Y A;  3APZ A;  5EAT A;  4P0V A;  3QQV A;  4KPD A;  2AEL A;  4GP2 A;  4KKM A;  2J1P A;  2AZL A;  5B01 A;  5EAS A;  3ICZ A;  5B0M A;  5ILI A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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