4LXWA

L72v epi-isozizaene synthase: complex with mg, inorganic pyrophosphate and benzyl triethyl ammonium cation
Total Genus 150
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
150
sequence length
340
structure length
340
Chain Sequence
AVPPSLRLPVIEAAFPRQLHPYWPKLQETTRTWLLEKRLMPADKVEEYADGLCYTDVMAGYYLGAPDEVLQAIADYSAWFFVWDDRHDRDIVHGRAGAWRRLRGLLHTALDSPGDHLHHEDTLVAGFADSVRRLYAFLPATWNARFARHFHTVIEAYDREFHNRTRGIVPGVEEYLELRRLTFAHWIWTDLLEPSSGCELPDAVRKHPAYRRAALLSQEFAAWYNDLCSLPKEIAGDEVHNLGISLITHHSLTLEEAIGEVRRRVEECITEFLAVERDALRFADELADGTVRGKELSGAVRANVGNMRNWFSSVYWFHHESGRYMVDSWDDRSTPPYVNN
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Reprogramming the Chemodiversity of Terpenoid Cyclization by Remolding the Active Site Contour of epi-Isozizaene Synthase.
pubmed doi rcsb
molecule tags Lyase
source organism Streptomyces coelicolor
molecule keywords Epi-isozizaene synthase
total genus 150
structure length 340
sequence length 340
ec nomenclature ec 4.2.3.37: Epi-isozizaene synthase.
pdb deposition date 2013-07-30
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.600.10 Mainly Alpha Orthogonal Bundle Farnesyl Diphosphate Synthase Farnesyl Diphosphate Synthase 4lxwA00
3CKEA 3Q1OA 4KQSA 5DJPF 4NKEA 3SDRA 2RAHA 5B01A 1VG2A 4FP4A 3V1VA 2J1OA 3QKCA 4OKMA 3LG5A 3M01A 4GAXA 3WSAA 4DHDA 3RYWA 5IKHA 3SDTA 5AELA 3P5RA 3WCBA 3ICKA 2Z4VA 3NPKA 3WE9A 3WCAA 1YJ4A 1WKZA 4LTVA 3KRFA 3N3DA 4F6VA 3ACWA 4JXNA 4XQRF 2H8OA 5IKAA 4LFVF 2Z7IA 1HX9A 2Q9YA 1DI1A 3DYHA 3P8RA 3ZMBA 2ZCQA 4KFAA 4NFKF 5ERNA 4HD1A 1YHLA 4KWDA 2E90A 5JUZF 2F94F 4GP1A 5ER8A 2E8XA 3QQVA 2P1CA 3VJ9A 3LVSA 3PKOA 3N1VF 4LOBA 2ONHA 4OKZA 2ZCSA 5DGMF 2F9KF 4LLSA 3WEHA 4ZQ8A 5CG5A 4KVDA 3WEJA 2AETA 4NFIF 3KRAB 4H5CF 4F6XA 3WJOA 3B7LA 3DYGA 2PS7A 3EGTA 5IVGA 4NUAA 1N22A 4FJQA 2FTZA 5ILDA 4LA5A 3PYAA 1WL0A 2E93A 4KVWA 5IL3A 3TFNA 1YYQA 1V4EA 2E95A 4LXWA 4RXCA 5B0MA 4K10A 4EA1A 2OPNA 4KPJA 4DI5A 3LGZB 2AEKA 4RXEA 2Z78A 3KB9A 5EASA 3VJ8A 1HXGA 1N23A 3WC9A 1VG7A 3IPIA 2AZJA 5DHKA 1KIZA 2Q80A 3KRCB 3WJNA 2FORA 3LOMA 3BNYA 5IMPA 3SDQA 4E9UA 2PS6A 3AE0A 3LDWA 5IL8A 4P0VA 2PS5A 3M0GA 3KBKA 4RYPA 3N0GA 3M00A 3LGKA 1YHKA 3M02A 1RTRA 2Z50A 3IBAA 2QISA 3VJDA 3CC9A 5E8LA 1JFAA 5C05A 3WCCA 4RXAA 3EZ3A 5B03A 5DGNF 5AYPA 3KROB 4OMHA 4DWBA 5EAUA 3KRAA 3LLWA 1YYTA 3N6KF 3LMDA 4DXJA 3V1XA 2OA6A 3AQCB 5HN9A 3RBMA 3NPRA 3CP6A 3N1WF 3WCFA 2J5CA 2Q58A 3WEGA 4MC8A 5DHIA 5HNAA 5B0JA 3SAEA 3M9UA 3TC1A 1V4IA 2E92A 3ASXA 2Z7HA 3WCHA 5A0JA 3ZMCA 3UCAA 3N46F 2ZY1A 4H5EF 5B0IA 2E94A 2J1PA 5IMNA 4KKMA 2VF6A 5EROA 5JA0F 1JFGA 3VJBA 3RYEA 2E8TA 4KPDA 3PYBA 3KRCA 4LFGA 1N1ZA 2AZKA 5DJVF 5ILHA 4KUXA 2ZEVA 2PS8A 1RQJA 5IMIA 4MC3A 1UBWA 5HN8A 4NG6A 3WCJA 4RNQA 4QPFA 1N1BA 3LK5A 3S4JA 5IN8A 3N49F 3LZ9A 1UBYA 3SDVA 4JZBA 5IK9A 3WEKA 2AZLA 3NRIA 5B02A 3KROA 3WEFA 3WCLA 2DH4A 1YV5A 3TFPA 2Q9ZA 3LSNA 3Q2QA 1N20A 1UBXA 1V4HA 5B0KA 1VG6A 1N24A 1ZW5A 2E8UA 5DZ2A 5AHUB 1YYSA 3APZA 3G4FA 2OGDA 3P8LA 1YQ7A 3N45F 2E8VA 5DIQF 4OGUA 3WCIA 2ONGA 3Q30A 3VJEA 2Z4WA 4DZWA 4KK2A 3KRPB 4LTZA 3WCDA 1V4KA 2Z4XA 1WL3A 4Q23A 5ILIA 5B00A 4RXDA 5AFXA 4LZCA 1FPSA 2ZCRA 3ACXA 4KVYA 5DJRF 5ILYA 5IM1A 3WJKA 4JVJF 5A0KA 2PS4A 3MZVA 5JV0F 3OACB 4EA2A 3OABB 5ILKA 4N1ZF 3VJAA 4WK5A 4MC0A 4P0XA 4LLTA 2Z4YA 3W7FA 3N5JF 1HM4A 1WY0A 2I19A 5B0LA 3BNXA 4DWGA 2E91A 3S9VA 2ZEUA 1WL1A 5HN7A 3RMGA 4JXYA 3N3LF 4N9UA 3OYRA 1YYUA 3ICMA 2Z52A 5I1UA 5JV2F 4LUUA 3MAVA 3ZOUA 3WCEA 5JV1F 5IK6A 3EFQA 1N21A 5H9DA 1HXCA 4QXSF 1PS1A 3WEIA 3SDUA 4KVIA 4UMJA 4F62A 3ZL6A 3WSBA 4XQTF 4DEMF 4E1EA 2E4OA 3KRPA 4LFEA 3V66A 3ID0A 3ACYA 3PDEA 1UBVA 3AQ0A 4LIXA 5DW7A 4H5DF 1YYRA 4P0WA 3ICZA 3KRFB 4LZ3A 2F89F 4NKFA 4E9ZA 3N0FA 3AQBB 4PVXF 3WCGA 1KIYA 5A0IA 3Q2ZA 1V4JA 5ILZA 4PVYF 3OACA 1WMWA 2F8CF 3OABA 5E8HA 3WCMA 4L2XF 3TS7A 2E8WA 1VG3A 3TFVA 3DYFA 3P41A 1WL2A 4KQUA 2AELA 4OMGA 1HM7A 4LPGF 2O1OA 3N5HF 5CG6A 3ADZA 1HXAA 3G4DA 3LJIA 4LPHF 3ICNA 1RQIA 5DGSF 4LA6A 4EA0A 4LZ0A 2OPMA 4JYXA 1YHMA 5ILJA 1DGPA 2EWGA 3P5PA 2F8ZF 4GP2A 1EZFA 2F92F 3VJCA 5IK0A 5E8KA 4JZXA 3ZCDA 2Z4ZA 2ZCOA 3PH7A 4NFJF 4GA3A 3NF2A 5ERMA 4XQSF 4KQ5A 3LEEA 5KSXF 2F7MF 5EATA 1VG4A
chains in the Genus database with same CATH superfamily
3CKEA 3Q1OA 4KQSA 5DJPF 4NKEA 3SDRA 2RAHA 5B01A 1VG2A 4FP4A 3V1VA 2J1OA 3QKCA 4OKMA 3LG5A 3M01A 4GAXA 3WSAA 4DHDA 3RYWA 5IKHA 3SDTA 5AELA 3P5RA 3WCBA 3ICKA 2Z4VA 3NPKA 3WE9A 3WCAA 1YJ4A 1WKZA 4LTVA 3KRFA 3N3DA 4F6VA 3ACWA 4JXNA 4XQRF 2H8OA 5IKAA 4LFVF 2Z7IA 1HX9A 2Q9YA 1DI1A 3DYHA 3P8RA 3ZMBA 2ZCQA 4KFAA 4NFKF 5ERNA 4HD1A 1YHLA 4KWDA 2E90A 5JUZF 2F94F 4GP1A 5ER8A 2E8XA 3QQVA 2P1CA 3VJ9A 3LVSA 3PKOA 3N1VF 4LOBA 2ONHA 4OKZA 2ZCSA 5DGMF 2F9KF 4LLSA 3WEHA 4ZQ8A 5CG5A 4KVDA 3WEJA 2AETA 4NFIF 3KRAB 4H5CF 4F6XA 3WJOA 3B7LA 3DYGA 2PS7A 3EGTA 5IVGA 4NUAA 1N22A 4FJQA 2FTZA 5ILDA 4LA5A 3PYAA 1WL0A 2E93A 4KVWA 5IL3A 3TFNA 1YYQA 1V4EA 2E95A 4LXWA 4RXCA 5B0MA 4K10A 4EA1A 2OPNA 4KPJA 4DI5A 3LGZB 2AEKA 4RXEA 2Z78A 3KB9A 5EASA 3VJ8A 1HXGA 1N23A 3WC9A 1VG7A 3IPIA 2AZJA 5DHKA 1KIZA 2Q80A 3KRCB 3WJNA 2FORA 3LOMA 3BNYA 5IMPA 3SDQA 4E9UA 2PS6A 3AE0A 3LDWA 5IL8A 4P0VA 2PS5A 3M0GA 3KBKA 4RYPA 3N0GA 3M00A 3LGKA 1YHKA 3M02A 1RTRA 2Z50A 3IBAA 2QISA 3VJDA 3CC9A 5E8LA 1JFAA 5C05A 3WCCA 4RXAA 3EZ3A 5B03A 5DGNF 5AYPA 3KROB 4OMHA 4DWBA 5EAUA 3KRAA 3LLWA 1YYTA 3N6KF 3LMDA 4DXJA 3V1XA 2OA6A 3AQCB 5HN9A 3RBMA 3NPRA 3CP6A 3N1WF 3WCFA 2J5CA 2Q58A 3WEGA 4MC8A 5DHIA 5HNAA 5B0JA 3SAEA 3M9UA 3TC1A 1V4IA 2E92A 3ASXA 2Z7HA 3WCHA 5A0JA 3ZMCA 3UCAA 3N46F 2ZY1A 4H5EF 5B0IA 2E94A 2J1PA 5IMNA 4KKMA 2VF6A 5EROA 5JA0F 1JFGA 3VJBA 3RYEA 2E8TA 4KPDA 3PYBA 3KRCA 4LFGA 1N1ZA 2AZKA 5DJVF 5ILHA 4KUXA 2ZEVA 2PS8A 1RQJA 5IMIA 4MC3A 1UBWA 5HN8A 4NG6A 3WCJA 4RNQA 4QPFA 1N1BA 3LK5A 3S4JA 5IN8A 3N49F 3LZ9A 1UBYA 3SDVA 4JZBA 5IK9A 3WEKA 2AZLA 3NRIA 5B02A 3KROA 3WEFA 3WCLA 2DH4A 1YV5A 3TFPA 2Q9ZA 3LSNA 3Q2QA 1N20A 1UBXA 1V4HA 5B0KA 1VG6A 1N24A 1ZW5A 2E8UA 5DZ2A 5AHUB 1YYSA 3APZA 3G4FA 2OGDA 3P8LA 1YQ7A 3N45F 2E8VA 5DIQF 4OGUA 3WCIA 2ONGA 3Q30A 3VJEA 2Z4WA 4DZWA 4KK2A 3KRPB 4LTZA 3WCDA 1V4KA 2Z4XA 1WL3A 4Q23A 5ILIA 5B00A 4RXDA 5AFXA 4LZCA 1FPSA 2ZCRA 3ACXA 4KVYA 5DJRF 5ILYA 5IM1A 3WJKA 4JVJF 5A0KA 2PS4A 3MZVA 5JV0F 3OACB 4EA2A 3OABB 5ILKA 4N1ZF 3VJAA 4WK5A 4MC0A 4P0XA 4LLTA 2Z4YA 3W7FA 3N5JF 1HM4A 1WY0A 2I19A 5B0LA 3BNXA 4DWGA 2E91A 3S9VA 2ZEUA 1WL1A 5HN7A 3RMGA 4JXYA 3N3LF 4N9UA 3OYRA 1YYUA 3ICMA 2Z52A 5I1UA 5JV2F 4LUUA 3MAVA 3ZOUA 3WCEA 5JV1F 5IK6A 3EFQA 1N21A 5H9DA 1HXCA 4QXSF 1PS1A 3WEIA 3SDUA 4KVIA 4UMJA 4F62A 3ZL6A 3WSBA 4XQTF 4DEMF 4E1EA 2E4OA 3KRPA 4LFEA 3V66A 3ID0A 3ACYA 3PDEA 1UBVA 3AQ0A 4LIXA 5DW7A 4H5DF 1YYRA 4P0WA 3ICZA 3KRFB 4LZ3A 2F89F 4NKFA 4E9ZA 3N0FA 3AQBB 4PVXF 3WCGA 1KIYA 5A0IA 3Q2ZA 1V4JA 5ILZA 4PVYF 3OACA 1WMWA 2F8CF 3OABA 5E8HA 3WCMA 4L2XF 3TS7A 2E8WA 1VG3A 3TFVA 3DYFA 3P41A 1WL2A 4KQUA 2AELA 4OMGA 1HM7A 4LPGF 2O1OA 3N5HF 5CG6A 3ADZA 1HXAA 3G4DA 3LJIA 4LPHF 3ICNA 1RQIA 5DGSF 4LA6A 4EA0A 4LZ0A 2OPMA 4JYXA 1YHMA 5ILJA 1DGPA 2EWGA 3P5PA 2F8ZF 4GP2A 1EZFA 2F92F 3VJCA 5IK0A 5E8KA 4JZXA 3ZCDA 2Z4ZA 2ZCOA 3PH7A 4NFJF 4GA3A 3NF2A 5ERMA 4XQSF 4KQ5A 3LEEA 5KSXF 2F7MF 5EATA 1VG4A
chains in the Genus database with same CATH topology
3CKEA 3Q1OA 4KQSA 5DJPF 4NKEA 3SDRA 2RAHA 5B01A 1VG2A 4FP4A 3V1VA 2J1OA 3QKCA 4OKMA 3LG5A 3M01A 4GAXA 3WSAA 4DHDA 3RYWA 5IKHA 3SDTA 5AELA 3P5RA 3WCBA 3ICKA 2Z4VA 3NPKA 3WE9A 3WCAA 1YJ4A 1WKZA 4LTVA 3KRFA 3N3DA 4F6VA 3ACWA 4JXNA 4XQRF 2H8OA 5IKAA 4LFVF 2Z7IA 1HX9A 2Q9YA 1DI1A 3DYHA 3P8RA 3ZMBA 2ZCQA 4KFAA 4NFKF 5ERNA 4HD1A 1YHLA 4KWDA 2E90A 5JUZF 2F94F 4GP1A 5ER8A 2E8XA 3QQVA 2P1CA 3VJ9A 3LVSA 3PKOA 3N1VF 4LOBA 2ONHA 4OKZA 2ZCSA 5DGMF 2F9KF 4LLSA 3WEHA 4ZQ8A 5CG5A 4KVDA 3WEJA 2AETA 4NFIF 3KRAB 4H5CF 4F6XA 3WJOA 3B7LA 3DYGA 2PS7A 3EGTA 5IVGA 4NUAA 1N22A 4FJQA 2FTZA 5ILDA 4LA5A 3PYAA 1WL0A 2E93A 4KVWA 5IL3A 3TFNA 1YYQA 1V4EA 2E95A 4LXWA 4RXCA 5B0MA 4K10A 4EA1A 2OPNA 4KPJA 4DI5A 3LGZB 2AEKA 4RXEA 2Z78A 3KB9A 5EASA 3VJ8A 1HXGA 1N23A 3WC9A 1VG7A 3IPIA 2AZJA 5DHKA 1KIZA 2Q80A 3KRCB 3WJNA 2FORA 3LOMA 3BNYA 5IMPA 3SDQA 4E9UA 2PS6A 3AE0A 3LDWA 5IL8A 4P0VA 2PS5A 3M0GA 3KBKA 4RYPA 3N0GA 3M00A 3LGKA 1YHKA 3M02A 1RTRA 2Z50A 3IBAA 2QISA 3VJDA 3CC9A 5E8LA 1JFAA 5C05A 3WCCA 4RXAA 3EZ3A 5B03A 5DGNF 5AYPA 3KROB 4OMHA 4DWBA 5EAUA 3KRAA 3LLWA 1YYTA 3N6KF 3LMDA 4DXJA 3V1XA 2OA6A 3AQCB 5HN9A 3RBMA 3NPRA 3CP6A 3N1WF 3WCFA 2J5CA 2Q58A 3WEGA 4MC8A 5DHIA 5HNAA 5B0JA 3SAEA 3M9UA 3TC1A 1V4IA 2E92A 3ASXA 2Z7HA 3WCHA 5A0JA 3ZMCA 3UCAA 3N46F 2ZY1A 4H5EF 5B0IA 2E94A 2J1PA 5IMNA 4KKMA 2VF6A 5EROA 5JA0F 1JFGA 3VJBA 3RYEA 2E8TA 4KPDA 3PYBA 3KRCA 4LFGA 1N1ZA 2AZKA 5DJVF 5ILHA 4KUXA 2ZEVA 2PS8A 1RQJA 5IMIA 4MC3A 1UBWA 5HN8A 4NG6A 3WCJA 4RNQA 4QPFA 1N1BA 3LK5A 3S4JA 5IN8A 3N49F 3LZ9A 1UBYA 3SDVA 4JZBA 5IK9A 3WEKA 2AZLA 3NRIA 5B02A 3KROA 3WEFA 3WCLA 2DH4A 1YV5A 3TFPA 2Q9ZA 3LSNA 3Q2QA 1N20A 1UBXA 1V4HA 5B0KA 1VG6A 1N24A 1ZW5A 2E8UA 5DZ2A 5AHUB 1YYSA 3APZA 3G4FA 2OGDA 3P8LA 1YQ7A 3N45F 2E8VA 5DIQF 4OGUA 3WCIA 2ONGA 3Q30A 3VJEA 2Z4WA 4DZWA 4KK2A 3KRPB 4LTZA 3WCDA 1V4KA 2Z4XA 1WL3A 4Q23A 5ILIA 5B00A 4RXDA 5AFXA 4LZCA 1FPSA 2ZCRA 3ACXA 4KVYA 5DJRF 5ILYA 5IM1A 3WJKA 4JVJF 5A0KA 2PS4A 3MZVA 5JV0F 3OACB 4EA2A 3OABB 5ILKA 4N1ZF 3VJAA 4WK5A 4MC0A 4P0XA 4LLTA 2Z4YA 3W7FA 3N5JF 1HM4A 1WY0A 2I19A 5B0LA 3BNXA 4DWGA 2E91A 3S9VA 2ZEUA 1WL1A 5HN7A 3RMGA 4JXYA 3N3LF 4N9UA 3OYRA 1YYUA 3ICMA 2Z52A 5I1UA 5JV2F 4LUUA 3MAVA 3ZOUA 3WCEA 5JV1F 5IK6A 3EFQA 1N21A 5H9DA 1HXCA 4QXSF 1PS1A 3WEIA 3SDUA 4KVIA 4UMJA 4F62A 3ZL6A 3WSBA 4XQTF 4DEMF 4E1EA 2E4OA 3KRPA 4LFEA 3V66A 3ID0A 3ACYA 3PDEA 1UBVA 3AQ0A 4LIXA 5DW7A 4H5DF 1YYRA 4P0WA 3ICZA 3KRFB 4LZ3A 2F89F 4NKFA 4E9ZA 3N0FA 3AQBB 4PVXF 3WCGA 1KIYA 5A0IA 3Q2ZA 1V4JA 5ILZA 4PVYF 3OACA 1WMWA 2F8CF 3OABA 5E8HA 3WCMA 4L2XF 3TS7A 2E8WA 1VG3A 3TFVA 3DYFA 3P41A 1WL2A 4KQUA 2AELA 4OMGA 1HM7A 4LPGF 2O1OA 3N5HF 5CG6A 3ADZA 1HXAA 3G4DA 3LJIA 4LPHF 3ICNA 1RQIA 5DGSF 4LA6A 4EA0A 4LZ0A 2OPMA 4JYXA 1YHMA 5ILJA 1DGPA 2EWGA 3P5PA 2F8ZF 4GP2A 1EZFA 2F92F 3VJCA 5IK0A 5E8KA 4JZXA 3ZCDA 2Z4ZA 2ZCOA 3PH7A 4NFJF 4GA3A 3NF2A 5ERMA 4XQSF 4KQ5A 3LEEA 5KSXF 2F7MF 5EATA 1VG4A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3CKE A;  3Q1O A;  4KQS A;  5DJP F;  4NKE A;  3SDR A;  2RAH A;  5B01 A;  1VG2 A;  4FP4 A;  3V1V A;  2J1O A;  3QKC A;  4OKM A;  3LG5 A;  3M01 A;  4GAX A;  3WSA A;  4DHD A;  3RYW A;  5IKH A;  3SDT A;  5AEL A;  3P5R A;  3WCB A;  3ICK A;  2Z4V A;  3NPK A;  3WE9 A;  3WCA A;  1YJ4 A;  1WKZ A;  4LTV A;  3KRF A;  3N3D A;  4F6V A;  3ACW A;  4JXN A;  4XQR F;  2H8O A;  5IKA A;  4LFV F;  2Z7I A;  1HX9 A;  2Q9Y A;  1DI1 A;  3DYH A;  3P8R A;  3ZMB A;  2ZCQ A;  4KFA A;  4NFK F;  5ERN A;  4HD1 A;  1YHL A;  4KWD A;  2E90 A;  5JUZ F;  2F94 F;  4GP1 A;  5ER8 A;  2E8X A;  3QQV A;  2P1C A;  3VJ9 A;  3LVS A;  3PKO A;  3N1V F;  4LOB A;  2ONH A;  4OKZ A;  2ZCS A;  5DGM F;  2F9K F;  4LLS A;  3WEH A;  4ZQ8 A;  5CG5 A;  4KVD A;  3WEJ A;  2AET A;  4NFI F;  3KRA B;  4H5C F;  4F6X A;  3WJO A;  3B7L A;  3DYG A;  2PS7 A;  3EGT A;  5IVG A;  4NUA A;  1N22 A;  4FJQ A;  2FTZ A;  5ILD A;  4LA5 A;  3PYA A;  1WL0 A;  2E93 A;  4KVW A;  5IL3 A;  3TFN A;  1YYQ A;  1V4E A;  2E95 A;  4LXW A;  4RXC A;  5B0M A;  4K10 A;  4EA1 A;  2OPN A;  4KPJ A;  4DI5 A;  3LGZ B;  2AEK A;  4RXE A;  2Z78 A;  3KB9 A;  5EAS A;  3VJ8 A;  1HXG A;  1N23 A;  3WC9 A;  1VG7 A;  3IPI A;  2AZJ A;  5DHK A;  1KIZ A;  2Q80 A;  3KRC B;  3WJN A;  2FOR A;  3LOM A;  3BNY A;  5IMP A;  3SDQ A;  4E9U A;  2PS6 A;  3AE0 A;  3LDW A;  5IL8 A;  4P0V A;  2PS5 A;  3M0G A;  3KBK A;  4RYP A;  3N0G A;  3M00 A;  3LGK A;  1YHK A;  3M02 A;  1RTR A;  2Z50 A;  3IBA A;  2QIS A;  3VJD A;  3CC9 A;  5E8L A;  1JFA A;  5C05 A;  3WCC A;  4RXA A;  3EZ3 A;  5B03 A;  5DGN F;  5AYP A;  3KRO B;  4OMH A;  4DWB A;  5EAU A;  3KRA A;  3LLW A;  1YYT A;  3N6K F;  3LMD A;  4DXJ A;  3V1X A;  2OA6 A;  3AQC B;  5HN9 A;  3RBM A;  3NPR A;  3CP6 A;  3N1W F;  3WCF A;  2J5C A;  2Q58 A;  3WEG A;  4MC8 A;  5DHI A;  5HNA A;  5B0J A;  3SAE A;  3M9U A;  3TC1 A;  1V4I A;  2E92 A;  3ASX A;  2Z7H A;  3WCH A;  5A0J A;  3ZMC A;  3UCA A;  3N46 F;  2ZY1 A;  4H5E F;  5B0I A;  2E94 A;  2J1P A;  5IMN A;  4KKM A;  2VF6 A;  5ERO A;  5JA0 F;  1JFG A;  3VJB A;  3RYE A;  2E8T A;  4KPD A;  3PYB A;  3KRC A;  4LFG A;  1N1Z A;  2AZK A;  5DJV F;  5ILH A;  4KUX A;  2ZEV A;  2PS8 A;  1RQJ A;  5IMI A;  4MC3 A;  1UBW A;  5HN8 A;  4NG6 A;  3WCJ A;  4RNQ A;  4QPF A;  1N1B A;  3LK5 A;  3S4J A;  5IN8 A;  3N49 F;  3LZ9 A;  1UBY A;  3SDV A;  4JZB A;  5IK9 A;  3WEK A;  2AZL A;  3NRI A;  5B02 A;  3KRO A;  3WEF A;  3WCL A;  2DH4 A;  1YV5 A;  3TFP A;  2Q9Z A;  3LSN A;  3Q2Q A;  1N20 A;  1UBX A;  1V4H A;  5B0K A;  1VG6 A;  1N24 A;  1ZW5 A;  2E8U A;  5DZ2 A;  5AHU B;  1YYS A;  3APZ A;  3G4F A;  2OGD A;  3P8L A;  1YQ7 A;  3N45 F;  2E8V A;  5DIQ F;  4OGU A;  3WCI A;  2ONG A;  3Q30 A;  3VJE A;  2Z4W A;  4DZW A;  4KK2 A;  3KRP B;  4LTZ A;  3WCD A;  1V4K A;  2Z4X A;  1WL3 A;  4Q23 A;  5ILI A;  5B00 A;  4RXD A;  5AFX A;  4LZC A;  1FPS A;  2ZCR A;  3ACX A;  4KVY A;  5DJR F;  5ILY A;  5IM1 A;  3WJK A;  4JVJ F;  5A0K A;  2PS4 A;  3MZV A;  5JV0 F;  3OAC B;  4EA2 A;  3OAB B;  5ILK A;  4N1Z F;  3VJA A;  4WK5 A;  4MC0 A;  4P0X A;  4LLT A;  2Z4Y A;  3W7F A;  3N5J F;  1HM4 A;  1WY0 A;  2I19 A;  5B0L A;  3BNX A;  4DWG A;  2E91 A;  3S9V A;  2ZEU A;  1WL1 A;  5HN7 A;  3RMG A;  4JXY A;  3N3L F;  4N9U A;  3OYR A;  1YYU A;  3ICM A;  2Z52 A;  5I1U A;  5JV2 F;  4LUU A;  3MAV A;  3ZOU A;  3WCE A;  5JV1 F;  5IK6 A;  3EFQ A;  1N21 A;  5H9D A;  1HXC A;  4QXS F;  1PS1 A;  3WEI A;  3SDU A;  4KVI A;  4UMJ A;  4F62 A;  3ZL6 A;  3WSB A;  4XQT F;  4DEM F;  4E1E A;  2E4O A;  3KRP A;  4LFE A;  3V66 A;  3ID0 A;  3ACY A;  3PDE A;  1UBV A;  3AQ0 A;  4LIX A;  5DW7 A;  4H5D F;  1YYR A;  4P0W A;  3ICZ A;  3KRF B;  4LZ3 A;  2F89 F;  4NKF A;  4E9Z A;  3N0F A;  3AQB B;  4PVX F;  3WCG A;  1KIY A;  5A0I A;  3Q2Z A;  1V4J A;  5ILZ A;  4PVY F;  3OAC A;  1WMW A;  2F8C F;  3OAB A;  5E8H A;  3WCM A;  4L2X F;  3TS7 A;  2E8W A;  1VG3 A;  3TFV A;  3DYF A;  3P41 A;  1WL2 A;  4KQU A;  2AEL A;  4OMG A;  1HM7 A;  4LPG F;  2O1O A;  3N5H F;  5CG6 A;  3ADZ A;  1HXA A;  3G4D A;  3LJI A;  4LPH F;  3ICN A;  1RQI A;  5DGS F;  4LA6 A;  4EA0 A;  4LZ0 A;  2OPM A;  4JYX A;  1YHM A;  5ILJ A;  1DGP A;  2EWG A;  3P5P A;  2F8Z F;  4GP2 A;  1EZF A;  2F92 F;  3VJC A;  5IK0 A;  5E8K A;  4JZX A;  3ZCD A;  2Z4Z A;  2ZCO A;  3PH7 A;  4NFJ F;  4GA3 A;  3NF2 A;  5ERM A;  4XQS F;  4KQ5 A;  3LEE A;  5KSX F;  2F7M F;  5EAT A;  1VG4 A; 
#chains in the Genus database with same CATH topology
 3CKE A;  3Q1O A;  4KQS A;  5DJP F;  4NKE A;  3SDR A;  2RAH A;  5B01 A;  1VG2 A;  4FP4 A;  3V1V A;  2J1O A;  3QKC A;  4OKM A;  3LG5 A;  3M01 A;  4GAX A;  3WSA A;  4DHD A;  3RYW A;  5IKH A;  3SDT A;  5AEL A;  3P5R A;  3WCB A;  3ICK A;  2Z4V A;  3NPK A;  3WE9 A;  3WCA A;  1YJ4 A;  1WKZ A;  4LTV A;  3KRF A;  3N3D A;  4F6V A;  3ACW A;  4JXN A;  4XQR F;  2H8O A;  5IKA A;  4LFV F;  2Z7I A;  1HX9 A;  2Q9Y A;  1DI1 A;  3DYH A;  3P8R A;  3ZMB A;  2ZCQ A;  4KFA A;  4NFK F;  5ERN A;  4HD1 A;  1YHL A;  4KWD A;  2E90 A;  5JUZ F;  2F94 F;  4GP1 A;  5ER8 A;  2E8X A;  3QQV A;  2P1C A;  3VJ9 A;  3LVS A;  3PKO A;  3N1V F;  4LOB A;  2ONH A;  4OKZ A;  2ZCS A;  5DGM F;  2F9K F;  4LLS A;  3WEH A;  4ZQ8 A;  5CG5 A;  4KVD A;  3WEJ A;  2AET A;  4NFI F;  3KRA B;  4H5C F;  4F6X A;  3WJO A;  3B7L A;  3DYG A;  2PS7 A;  3EGT A;  5IVG A;  4NUA A;  1N22 A;  4FJQ A;  2FTZ A;  5ILD A;  4LA5 A;  3PYA A;  1WL0 A;  2E93 A;  4KVW A;  5IL3 A;  3TFN A;  1YYQ A;  1V4E A;  2E95 A;  4LXW A;  4RXC A;  5B0M A;  4K10 A;  4EA1 A;  2OPN A;  4KPJ A;  4DI5 A;  3LGZ B;  2AEK A;  4RXE A;  2Z78 A;  3KB9 A;  5EAS A;  3VJ8 A;  1HXG A;  1N23 A;  3WC9 A;  1VG7 A;  3IPI A;  2AZJ A;  5DHK A;  1KIZ A;  2Q80 A;  3KRC B;  3WJN A;  2FOR A;  3LOM A;  3BNY A;  5IMP A;  3SDQ A;  4E9U A;  2PS6 A;  3AE0 A;  3LDW A;  5IL8 A;  4P0V A;  2PS5 A;  3M0G A;  3KBK A;  4RYP A;  3N0G A;  3M00 A;  3LGK A;  1YHK A;  3M02 A;  1RTR A;  2Z50 A;  3IBA A;  2QIS A;  3VJD A;  3CC9 A;  5E8L A;  1JFA A;  5C05 A;  3WCC A;  4RXA A;  3EZ3 A;  5B03 A;  5DGN F;  5AYP A;  3KRO B;  4OMH A;  4DWB A;  5EAU A;  3KRA A;  3LLW A;  1YYT A;  3N6K F;  3LMD A;  4DXJ A;  3V1X A;  2OA6 A;  3AQC B;  5HN9 A;  3RBM A;  3NPR A;  3CP6 A;  3N1W F;  3WCF A;  2J5C A;  2Q58 A;  3WEG A;  4MC8 A;  5DHI A;  5HNA A;  5B0J A;  3SAE A;  3M9U A;  3TC1 A;  1V4I A;  2E92 A;  3ASX A;  2Z7H A;  3WCH A;  5A0J A;  3ZMC A;  3UCA A;  3N46 F;  2ZY1 A;  4H5E F;  5B0I A;  2E94 A;  2J1P A;  5IMN A;  4KKM A;  2VF6 A;  5ERO A;  5JA0 F;  1JFG A;  3VJB A;  3RYE A;  2E8T A;  4KPD A;  3PYB A;  3KRC A;  4LFG A;  1N1Z A;  2AZK A;  5DJV F;  5ILH A;  4KUX A;  2ZEV A;  2PS8 A;  1RQJ A;  5IMI A;  4MC3 A;  1UBW A;  5HN8 A;  4NG6 A;  3WCJ A;  4RNQ A;  4QPF A;  1N1B A;  3LK5 A;  3S4J A;  5IN8 A;  3N49 F;  3LZ9 A;  1UBY A;  3SDV A;  4JZB A;  5IK9 A;  3WEK A;  2AZL A;  3NRI A;  5B02 A;  3KRO A;  3WEF A;  3WCL A;  2DH4 A;  1YV5 A;  3TFP A;  2Q9Z A;  3LSN A;  3Q2Q A;  1N20 A;  1UBX A;  1V4H A;  5B0K A;  1VG6 A;  1N24 A;  1ZW5 A;  2E8U A;  5DZ2 A;  5AHU B;  1YYS A;  3APZ A;  3G4F A;  2OGD A;  3P8L A;  1YQ7 A;  3N45 F;  2E8V A;  5DIQ F;  4OGU A;  3WCI A;  2ONG A;  3Q30 A;  3VJE A;  2Z4W A;  4DZW A;  4KK2 A;  3KRP B;  4LTZ A;  3WCD A;  1V4K A;  2Z4X A;  1WL3 A;  4Q23 A;  5ILI A;  5B00 A;  4RXD A;  5AFX A;  4LZC A;  1FPS A;  2ZCR A;  3ACX A;  4KVY A;  5DJR F;  5ILY A;  5IM1 A;  3WJK A;  4JVJ F;  5A0K A;  2PS4 A;  3MZV A;  5JV0 F;  3OAC B;  4EA2 A;  3OAB B;  5ILK A;  4N1Z F;  3VJA A;  4WK5 A;  4MC0 A;  4P0X A;  4LLT A;  2Z4Y A;  3W7F A;  3N5J F;  1HM4 A;  1WY0 A;  2I19 A;  5B0L A;  3BNX A;  4DWG A;  2E91 A;  3S9V A;  2ZEU A;  1WL1 A;  5HN7 A;  3RMG A;  4JXY A;  3N3L F;  4N9U A;  3OYR A;  1YYU A;  3ICM A;  2Z52 A;  5I1U A;  5JV2 F;  4LUU A;  3MAV A;  3ZOU A;  3WCE A;  5JV1 F;  5IK6 A;  3EFQ A;  1N21 A;  5H9D A;  1HXC A;  4QXS F;  1PS1 A;  3WEI A;  3SDU A;  4KVI A;  4UMJ A;  4F62 A;  3ZL6 A;  3WSB A;  4XQT F;  4DEM F;  4E1E A;  2E4O A;  3KRP A;  4LFE A;  3V66 A;  3ID0 A;  3ACY A;  3PDE A;  1UBV A;  3AQ0 A;  4LIX A;  5DW7 A;  4H5D F;  1YYR A;  4P0W A;  3ICZ A;  3KRF B;  4LZ3 A;  2F89 F;  4NKF A;  4E9Z A;  3N0F A;  3AQB B;  4PVX F;  3WCG A;  1KIY A;  5A0I A;  3Q2Z A;  1V4J A;  5ILZ A;  4PVY F;  3OAC A;  1WMW A;  2F8C F;  3OAB A;  5E8H A;  3WCM A;  4L2X F;  3TS7 A;  2E8W A;  1VG3 A;  3TFV A;  3DYF A;  3P41 A;  1WL2 A;  4KQU A;  2AEL A;  4OMG A;  1HM7 A;  4LPG F;  2O1O A;  3N5H F;  5CG6 A;  3ADZ A;  1HXA A;  3G4D A;  3LJI A;  4LPH F;  3ICN A;  1RQI A;  5DGS F;  4LA6 A;  4EA0 A;  4LZ0 A;  2OPM A;  4JYX A;  1YHM A;  5ILJ A;  1DGP A;  2EWG A;  3P5P A;  2F8Z F;  4GP2 A;  1EZF A;  2F92 F;  3VJC A;  5IK0 A;  5E8K A;  4JZX A;  3ZCD A;  2Z4Z A;  2ZCO A;  3PH7 A;  4NFJ F;  4GA3 A;  3NF2 A;  5ERM A;  4XQS F;  4KQ5 A;  3LEE A;  5KSX F;  2F7M F;  5EAT A;  1VG4 A; 
#chains in the Genus database with same CATH homology
 3CKE A;  3Q1O A;  4KQS A;  5DJP F;  4NKE A;  3SDR A;  2RAH A;  5B01 A;  1VG2 A;  4FP4 A;  3V1V A;  2J1O A;  3QKC A;  4OKM A;  3LG5 A;  3M01 A;  4GAX A;  3WSA A;  4DHD A;  3RYW A;  5IKH A;  3SDT A;  5AEL A;  3P5R A;  3WCB A;  3ICK A;  2Z4V A;  3NPK A;  3WE9 A;  3WCA A;  1YJ4 A;  1WKZ A;  4LTV A;  3KRF A;  3N3D A;  4F6V A;  3ACW A;  4JXN A;  4XQR F;  2H8O A;  5IKA A;  4LFV F;  2Z7I A;  1HX9 A;  2Q9Y A;  1DI1 A;  3DYH A;  3P8R A;  3ZMB A;  2ZCQ A;  4KFA A;  4NFK F;  5ERN A;  4HD1 A;  1YHL A;  4KWD A;  2E90 A;  5JUZ F;  2F94 F;  4GP1 A;  5ER8 A;  2E8X A;  3QQV A;  2P1C A;  3VJ9 A;  3LVS A;  3PKO A;  3N1V F;  4LOB A;  2ONH A;  4OKZ A;  2ZCS A;  5DGM F;  2F9K F;  4LLS A;  3WEH A;  4ZQ8 A;  5CG5 A;  4KVD A;  3WEJ A;  2AET A;  4NFI F;  3KRA B;  4H5C F;  4F6X A;  3WJO A;  3B7L A;  3DYG A;  2PS7 A;  3EGT A;  5IVG A;  4NUA A;  1N22 A;  4FJQ A;  2FTZ A;  5ILD A;  4LA5 A;  3PYA A;  1WL0 A;  2E93 A;  4KVW A;  5IL3 A;  3TFN A;  1YYQ A;  1V4E A;  2E95 A;  4LXW A;  4RXC A;  5B0M A;  4K10 A;  4EA1 A;  2OPN A;  4KPJ A;  4DI5 A;  3LGZ B;  2AEK A;  4RXE A;  2Z78 A;  3KB9 A;  5EAS A;  3VJ8 A;  1HXG A;  1N23 A;  3WC9 A;  1VG7 A;  3IPI A;  2AZJ A;  5DHK A;  1KIZ A;  2Q80 A;  3KRC B;  3WJN A;  2FOR A;  3LOM A;  3BNY A;  5IMP A;  3SDQ A;  4E9U A;  2PS6 A;  3AE0 A;  3LDW A;  5IL8 A;  4P0V A;  2PS5 A;  3M0G A;  3KBK A;  4RYP A;  3N0G A;  3M00 A;  3LGK A;  1YHK A;  3M02 A;  1RTR A;  2Z50 A;  3IBA A;  2QIS A;  3VJD A;  3CC9 A;  5E8L A;  1JFA A;  5C05 A;  3WCC A;  4RXA A;  3EZ3 A;  5B03 A;  5DGN F;  5AYP A;  3KRO B;  4OMH A;  4DWB A;  5EAU A;  3KRA A;  3LLW A;  1YYT A;  3N6K F;  3LMD A;  4DXJ A;  3V1X A;  2OA6 A;  3AQC B;  5HN9 A;  3RBM A;  3NPR A;  3CP6 A;  3N1W F;  3WCF A;  2J5C A;  2Q58 A;  3WEG A;  4MC8 A;  5DHI A;  5HNA A;  5B0J A;  3SAE A;  3M9U A;  3TC1 A;  1V4I A;  2E92 A;  3ASX A;  2Z7H A;  3WCH A;  5A0J A;  3ZMC A;  3UCA A;  3N46 F;  2ZY1 A;  4H5E F;  5B0I A;  2E94 A;  2J1P A;  5IMN A;  4KKM A;  2VF6 A;  5ERO A;  5JA0 F;  1JFG A;  3VJB A;  3RYE A;  2E8T A;  4KPD A;  3PYB A;  3KRC A;  4LFG A;  1N1Z A;  2AZK A;  5DJV F;  5ILH A;  4KUX A;  2ZEV A;  2PS8 A;  1RQJ A;  5IMI A;  4MC3 A;  1UBW A;  5HN8 A;  4NG6 A;  3WCJ A;  4RNQ A;  4QPF A;  1N1B A;  3LK5 A;  3S4J A;  5IN8 A;  3N49 F;  3LZ9 A;  1UBY A;  3SDV A;  4JZB A;  5IK9 A;  3WEK A;  2AZL A;  3NRI A;  5B02 A;  3KRO A;  3WEF A;  3WCL A;  2DH4 A;  1YV5 A;  3TFP A;  2Q9Z A;  3LSN A;  3Q2Q A;  1N20 A;  1UBX A;  1V4H A;  5B0K A;  1VG6 A;  1N24 A;  1ZW5 A;  2E8U A;  5DZ2 A;  5AHU B;  1YYS A;  3APZ A;  3G4F A;  2OGD A;  3P8L A;  1YQ7 A;  3N45 F;  2E8V A;  5DIQ F;  4OGU A;  3WCI A;  2ONG A;  3Q30 A;  3VJE A;  2Z4W A;  4DZW A;  4KK2 A;  3KRP B;  4LTZ A;  3WCD A;  1V4K A;  2Z4X A;  1WL3 A;  4Q23 A;  5ILI A;  5B00 A;  4RXD A;  5AFX A;  4LZC A;  1FPS A;  2ZCR A;  3ACX A;  4KVY A;  5DJR F;  5ILY A;  5IM1 A;  3WJK A;  4JVJ F;  5A0K A;  2PS4 A;  3MZV A;  5JV0 F;  3OAC B;  4EA2 A;  3OAB B;  5ILK A;  4N1Z F;  3VJA A;  4WK5 A;  4MC0 A;  4P0X A;  4LLT A;  2Z4Y A;  3W7F A;  3N5J F;  1HM4 A;  1WY0 A;  2I19 A;  5B0L A;  3BNX A;  4DWG A;  2E91 A;  3S9V A;  2ZEU A;  1WL1 A;  5HN7 A;  3RMG A;  4JXY A;  3N3L F;  4N9U A;  3OYR A;  1YYU A;  3ICM A;  2Z52 A;  5I1U A;  5JV2 F;  4LUU A;  3MAV A;  3ZOU A;  3WCE A;  5JV1 F;  5IK6 A;  3EFQ A;  1N21 A;  5H9D A;  1HXC A;  4QXS F;  1PS1 A;  3WEI A;  3SDU A;  4KVI A;  4UMJ A;  4F62 A;  3ZL6 A;  3WSB A;  4XQT F;  4DEM F;  4E1E A;  2E4O A;  3KRP A;  4LFE A;  3V66 A;  3ID0 A;  3ACY A;  3PDE A;  1UBV A;  3AQ0 A;  4LIX A;  5DW7 A;  4H5D F;  1YYR A;  4P0W A;  3ICZ A;  3KRF B;  4LZ3 A;  2F89 F;  4NKF A;  4E9Z A;  3N0F A;  3AQB B;  4PVX F;  3WCG A;  1KIY A;  5A0I A;  3Q2Z A;  1V4J A;  5ILZ A;  4PVY F;  3OAC A;  1WMW A;  2F8C F;  3OAB A;  5E8H A;  3WCM A;  4L2X F;  3TS7 A;  2E8W A;  1VG3 A;  3TFV A;  3DYF A;  3P41 A;  1WL2 A;  4KQU A;  2AEL A;  4OMG A;  1HM7 A;  4LPG F;  2O1O A;  3N5H F;  5CG6 A;  3ADZ A;  1HXA A;  3G4D A;  3LJI A;  4LPH F;  3ICN A;  1RQI A;  5DGS F;  4LA6 A;  4EA0 A;  4LZ0 A;  2OPM A;  4JYX A;  1YHM A;  5ILJ A;  1DGP A;  2EWG A;  3P5P A;  2F8Z F;  4GP2 A;  1EZF A;  2F92 F;  3VJC A;  5IK0 A;  5E8K A;  4JZX A;  3ZCD A;  2Z4Z A;  2ZCO A;  3PH7 A;  4NFJ F;  4GA3 A;  3NF2 A;  5ERM A;  4XQS F;  4KQ5 A;  3LEE A;  5KSX F;  2F7M F;  5EAT A;  1VG4 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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