4N1ZF

Crystal structure of human farnesyl diphosphate synthase in complex with bph-1222
Total Genus 127
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
127
sequence length
340
structure length
333
Chain Sequence
VYAQEKQDFVQHFSQIVRVLTHPEIGDAIARLKEVLEYNAIGGKYNRGLTVVVAFRELVEPRKQDADSLQRAWTVGWCVELLQAFFLVADDIMDSSLTRRGQICWYQKPGVGLDAINDANLLEACIYRLLKLYCREQPYYLNLIELFLQSSYQTEIGQTLDLLTAPQGNLVRFTEKRYKSIVKYKTAFYSFYLPIAAAMYMAGIDGEKEHANAKKILLEMGEFFQIQDDYLDLFGDPSVTGKIGTDIQDNKCSWLVVQCLQRATPEQYQILKENYGQKEAEKVARVKALYEELDLPAVFLQYEEDSYSHIMALIEQYAAPLPPAVFLGLARKI
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title A combination therapy for KRAS-driven lung adenocarcinomas using lipophilic bisphosphonates and rapamycin.
pubmed doi rcsb
molecule tags Transferase
source organism Homo sapiens
molecule keywords Farnesyl pyrophosphate synthase
total genus 127
structure length 333
sequence length 340
ec nomenclature ec 2.5.1.1: Dimethylallyltranstransferase.
pdb deposition date 2013-10-04

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
F PF00348 polyprenyl_synt Polyprenyl synthetase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.600.10 Mainly Alpha Orthogonal Bundle Farnesyl Diphosphate Synthase Farnesyl Diphosphate Synthase 4n1zF00
5AYPA 3KRAA 4NKFA 1WKZA 3ICKA 4LFVF 4UMJA 4XQTF 5DGSF 1HXCA 3LSNA 4NKEA 5DHIA 2PS6A 2J1OA 1YJ4A 3VJ9A 5DGNF 4MC8A 4H5CF 4MC3A 4F6XA 2ONHA 2ONGA 4DZWA 4XQSF 5A0IA 4KFAA 2AZJA 5I1UA 1N1ZA 1YV5A 4LOBA 1VG6A 2E8UA 1YYQA 2PS4A 4JXNA 3WEHA 3LZ9A 5DIQF 3TS7A 3S4JA 5B02A 1V4IA 2E4OA 3OACB 4EA0A 3V1XA 4RXAA 2J5CA 3LEEA 4OKMA 4KVIA 4LZ3A 3WCFA 4P0VA 2E95A 2DH4A 2E93A 3N5HF 2H8OA 3N49F 3OABB 2I19A 4LXWA 3ACYA 1VG2A 3UCAA 4RYPA 2VF6A 3P41A 2ZCRA 1V4KA 3CC9A 4OMHA 2Z4VA 2ZY1A 3DYFA 4E9UA 5B01A 3G4DA 1KIYA 3SDUA 3V1VA 3WEJA 2FTZA 3N1VF 3WEGA 5E8LA 1N24A 1HM4A 3WCEA 3MAVA 2Q9ZA 2OPMA 1HXGA 4DEMF 4GA3A 2ZCSA 3TC1A 2RAHA 1YYUA 5ILDA 5ILHA 4GP1A 3N0GA 3PH7A 4JVJF 5EROA 2OGDA 1YYTA 3BNXA 3V66A 2J1PA 5KSXF 5AHUB 3WJNA 2ZEVA 4KQSA 4KQUA 3ZCDA 1JFAA 3KRAB 5DGMF 2F8CF 5E8HA 3LVSA 5EATA 3TFVA 4NG6A 5B03A 3NPKA 3KROB 2Z50A 3Q2ZA 4L2XF 3WSAA 3ZMCA 3ZL6A 4KVWA 5ER8A 5HN8A 3M02A 4RXDA 3TFNA 4F6VA 1UBVA 3P8LA 5ERNA 3G4FA 5JUZF 3WCCA 4XQRF 3N6KF 3WCGA 3N1WF 2E92A 5IMIA 3Q2QA 2PS7A 5E8KA 5B0KA 1YHLA 5IKAA 1RQIA 3CKEA 3SDQA 5B00A 3ZMBA 1UBXA 3WCAA 1HXAA 3AQBB 4E1EA 3LJIA 5C05A 2E90A 2AZKA 3QQVA 3KRCA 1DGPA 3ID0A 3RMGA 4KPDA 4LUUA 4JXYA 3ZOUA 4LPHF 3APZA 5IK0A 1WMWA 4KWDA 4QXSF 2PS5A 5B0JA 3W7FA 4DI5A 5B0IA 1KIZA 3N3DA 1V4EA 3IBAA 5H9DA 3VJAA 1FPSA 3WCHA 1N23A 4Q23A 3EFQA 5EAUA 3EZ3A 1YYRA 5IM1A 2E91A 3N5JF 5B0LA 4DXJA 4KKMA 2E8TA 1V4HA 4H5DF 2F9KF 3WC9A 1WL1A 5IMPA 2F92F 3S9VA 1HX9A 2E8XA 4E9ZA 3VJDA 1YQ7A 3VJBA 4ZQ8A 4EA2A 5HN9A 3BNYA 1VG3A 4JZBA 4LTVA 4LA5A 3WE9A 4DWBA 4OKZA 5ILKA 1RQJA 2Z4XA 3EGTA 4PVXF 5ILJA 2EWGA 3WCBA 3VJEA 1N20A 3ADZA 3SDRA 5JV2F 3WCDA 3ICMA 5JV0F 5ERMA 3WJOA 1YYSA 3KRFB 1N22A 4FJQA 5AELA 4EA1A 5IL8A 1ZW5A 4QPFA 3IPIA 4GP2A 4LTZA 3N46F 3WEFA 2E8VA 3DYHA 4LZ0A 5IL3A 3Q1OA 4RXCA 2Z4YA 4KUXA 5DHKA 3N0FA 3PYAA 2PS8A 5CG5A 4OMGA 3AQCB 3KRPA 5IVGA 4NFJF 5ILYA 4LA6A 5DJRF 5CG6A 4RNQA 2F89F 3SDVA 4OGUA 3PKOA 2QISA 3N3LF 2AZLA 3OYRA 5EASA 1WY0A 2Q58A 3WSBA 3NRIA 1UBYA 2Z52A 5IK9A 4MC0A 4KVYA 3KROA 5IMNA 1UBWA 3AE0A 5DJPF 3WJKA 2Z4ZA 5IK6A 2Z7HA 3KRCB 3WCLA 3P5RA 4LFEA 1N21A 3ASXA 3NF2A 1YHKA 1VG7A 2AEKA 1WL0A 3PYBA 3SAEA 3LK5A 3TFPA 1DI1A 3ACXA 5IN8A 2E94A 5JV1F 2OA6A 5IKHA 4DHDA 2O1OA 4LFGA 4N9UA 3WCIA 3SDTA 2AETA 4LPGF 3LOMA 2ZEUA 4K10A 5DW7A 2Q80A 3B7LA 1VG4A 3N45F 2OPNA 5ILZA 3OACA 3RYEA 1V4JA 5A0JA 5DZ2A 2F94F 3PDEA 3M01A 4N1ZF 2F8ZF 5ILIA 3WCMA 2ZCQA 3P8RA 4RXEA 2Z78A 1JFGA 3VJ8A 4KPJA 4NFIF 2FORA 2Z4WA 3KBKA 1RTRA 3LDWA 3QKCA 4LZCA 3OABA 4WK5A 3ICNA 3M0GA 3WCJA 3WEKA 2ZCOA 5HNAA 4LIXA 4JYXA 3KB9A 3AQ0A 4GAXA 4FP4A 3LGZB 1WL3A 4PVYF 1YHMA 4LLTA 3ICZA 4NUAA 3WEIA 1EZFA 1PS1A 1WL2A 3DYGA 4H5EF 3RBMA 4P0XA 5A0KA 4P0WA 3LMDA 3P5PA 5DJVF 4JZXA 4KK2A 1N1BA 2AELA 3M00A 4NFKF 2E8WA 2P1CA 3LGKA 4KVDA 4KQ5A 3VJCA 3MZVA 4HD1A 3LG5A 3M9UA 3NPRA 4DWGA 4F62A 2Q9YA 2Z7IA 3KRPB 3CP6A 5B0MA 4LLSA 3RYWA 2F7MF 3ACWA 3Q30A 3KRFA 5HN7A 1HM7A 3LLWA 5AFXA 5JA0F
chains in the Genus database with same CATH superfamily
5AYPA 3KRAA 4NKFA 1WKZA 3ICKA 4LFVF 4UMJA 4XQTF 5DGSF 1HXCA 3LSNA 4NKEA 5DHIA 2PS6A 2J1OA 1YJ4A 3VJ9A 5DGNF 4MC8A 4H5CF 4MC3A 4F6XA 2ONHA 2ONGA 4DZWA 4XQSF 5A0IA 4KFAA 2AZJA 5I1UA 1N1ZA 1YV5A 4LOBA 1VG6A 2E8UA 1YYQA 2PS4A 4JXNA 3WEHA 3LZ9A 5DIQF 3TS7A 3S4JA 5B02A 1V4IA 2E4OA 3OACB 4EA0A 3V1XA 4RXAA 2J5CA 3LEEA 4OKMA 4KVIA 4LZ3A 3WCFA 4P0VA 2E95A 2DH4A 2E93A 3N5HF 2H8OA 3N49F 3OABB 2I19A 4LXWA 3ACYA 1VG2A 3UCAA 4RYPA 2VF6A 3P41A 2ZCRA 1V4KA 3CC9A 4OMHA 2Z4VA 2ZY1A 3DYFA 4E9UA 5B01A 3G4DA 1KIYA 3SDUA 3V1VA 3WEJA 2FTZA 3N1VF 3WEGA 5E8LA 1N24A 1HM4A 3WCEA 3MAVA 2Q9ZA 2OPMA 1HXGA 4DEMF 4GA3A 2ZCSA 3TC1A 2RAHA 1YYUA 5ILDA 5ILHA 4GP1A 3N0GA 3PH7A 4JVJF 5EROA 2OGDA 1YYTA 3BNXA 3V66A 2J1PA 5KSXF 5AHUB 3WJNA 2ZEVA 4KQSA 4KQUA 3ZCDA 1JFAA 3KRAB 5DGMF 2F8CF 5E8HA 3LVSA 5EATA 3TFVA 4NG6A 5B03A 3NPKA 3KROB 2Z50A 3Q2ZA 4L2XF 3WSAA 3ZMCA 3ZL6A 4KVWA 5ER8A 5HN8A 3M02A 4RXDA 3TFNA 4F6VA 1UBVA 3P8LA 5ERNA 3G4FA 5JUZF 3WCCA 4XQRF 3N6KF 3WCGA 3N1WF 2E92A 5IMIA 3Q2QA 2PS7A 5E8KA 5B0KA 1YHLA 5IKAA 1RQIA 3CKEA 3SDQA 5B00A 3ZMBA 1UBXA 3WCAA 1HXAA 3AQBB 4E1EA 3LJIA 5C05A 2E90A 2AZKA 3QQVA 3KRCA 1DGPA 3ID0A 3RMGA 4KPDA 4LUUA 4JXYA 3ZOUA 4LPHF 3APZA 5IK0A 1WMWA 4KWDA 4QXSF 2PS5A 5B0JA 3W7FA 4DI5A 5B0IA 1KIZA 3N3DA 1V4EA 3IBAA 5H9DA 3VJAA 1FPSA 3WCHA 1N23A 4Q23A 3EFQA 5EAUA 3EZ3A 1YYRA 5IM1A 2E91A 3N5JF 5B0LA 4DXJA 4KKMA 2E8TA 1V4HA 4H5DF 2F9KF 3WC9A 1WL1A 5IMPA 2F92F 3S9VA 1HX9A 2E8XA 4E9ZA 3VJDA 1YQ7A 3VJBA 4ZQ8A 4EA2A 5HN9A 3BNYA 1VG3A 4JZBA 4LTVA 4LA5A 3WE9A 4DWBA 4OKZA 5ILKA 1RQJA 2Z4XA 3EGTA 4PVXF 5ILJA 2EWGA 3WCBA 3VJEA 1N20A 3ADZA 3SDRA 5JV2F 3WCDA 3ICMA 5JV0F 5ERMA 3WJOA 1YYSA 3KRFB 1N22A 4FJQA 5AELA 4EA1A 5IL8A 1ZW5A 4QPFA 3IPIA 4GP2A 4LTZA 3N46F 3WEFA 2E8VA 3DYHA 4LZ0A 5IL3A 3Q1OA 4RXCA 2Z4YA 4KUXA 5DHKA 3N0FA 3PYAA 2PS8A 5CG5A 4OMGA 3AQCB 3KRPA 5IVGA 4NFJF 5ILYA 4LA6A 5DJRF 5CG6A 4RNQA 2F89F 3SDVA 4OGUA 3PKOA 2QISA 3N3LF 2AZLA 3OYRA 5EASA 1WY0A 2Q58A 3WSBA 3NRIA 1UBYA 2Z52A 5IK9A 4MC0A 4KVYA 3KROA 5IMNA 1UBWA 3AE0A 5DJPF 3WJKA 2Z4ZA 5IK6A 2Z7HA 3KRCB 3WCLA 3P5RA 4LFEA 1N21A 3ASXA 3NF2A 1YHKA 1VG7A 2AEKA 1WL0A 3PYBA 3SAEA 3LK5A 3TFPA 1DI1A 3ACXA 5IN8A 2E94A 5JV1F 2OA6A 5IKHA 4DHDA 2O1OA 4LFGA 4N9UA 3WCIA 3SDTA 2AETA 4LPGF 3LOMA 2ZEUA 4K10A 5DW7A 2Q80A 3B7LA 1VG4A 3N45F 2OPNA 5ILZA 3OACA 3RYEA 1V4JA 5A0JA 5DZ2A 2F94F 3PDEA 3M01A 4N1ZF 2F8ZF 5ILIA 3WCMA 2ZCQA 3P8RA 4RXEA 2Z78A 1JFGA 3VJ8A 4KPJA 4NFIF 2FORA 2Z4WA 3KBKA 1RTRA 3LDWA 3QKCA 4LZCA 3OABA 4WK5A 3ICNA 3M0GA 3WCJA 3WEKA 2ZCOA 5HNAA 4LIXA 4JYXA 3KB9A 3AQ0A 4GAXA 4FP4A 3LGZB 1WL3A 4PVYF 1YHMA 4LLTA 3ICZA 4NUAA 3WEIA 1EZFA 1PS1A 1WL2A 3DYGA 4H5EF 3RBMA 4P0XA 5A0KA 4P0WA 3LMDA 3P5PA 5DJVF 4JZXA 4KK2A 1N1BA 2AELA 3M00A 4NFKF 2E8WA 2P1CA 3LGKA 4KVDA 4KQ5A 3VJCA 3MZVA 4HD1A 3LG5A 3M9UA 3NPRA 4DWGA 4F62A 2Q9YA 2Z7IA 3KRPB 3CP6A 5B0MA 4LLSA 3RYWA 2F7MF 3ACWA 3Q30A 3KRFA 5HN7A 1HM7A 3LLWA 5AFXA 5JA0F
chains in the Genus database with same CATH topology
5AYPA 3KRAA 4NKFA 1WKZA 3ICKA 4LFVF 4UMJA 4XQTF 5DGSF 1HXCA 3LSNA 4NKEA 5DHIA 2PS6A 2J1OA 1YJ4A 3VJ9A 5DGNF 4MC8A 4H5CF 4MC3A 4F6XA 2ONHA 2ONGA 4DZWA 4XQSF 5A0IA 4KFAA 2AZJA 5I1UA 1N1ZA 1YV5A 4LOBA 1VG6A 2E8UA 1YYQA 2PS4A 4JXNA 3WEHA 3LZ9A 5DIQF 3TS7A 3S4JA 5B02A 1V4IA 2E4OA 3OACB 4EA0A 3V1XA 4RXAA 2J5CA 3LEEA 4OKMA 4KVIA 4LZ3A 3WCFA 4P0VA 2E95A 2DH4A 2E93A 3N5HF 2H8OA 3N49F 3OABB 2I19A 4LXWA 3ACYA 1VG2A 3UCAA 4RYPA 2VF6A 3P41A 2ZCRA 1V4KA 3CC9A 4OMHA 2Z4VA 2ZY1A 3DYFA 4E9UA 5B01A 3G4DA 1KIYA 3SDUA 3V1VA 3WEJA 2FTZA 3N1VF 3WEGA 5E8LA 1N24A 1HM4A 3WCEA 3MAVA 2Q9ZA 2OPMA 1HXGA 4DEMF 4GA3A 2ZCSA 3TC1A 2RAHA 1YYUA 5ILDA 5ILHA 4GP1A 3N0GA 3PH7A 4JVJF 5EROA 2OGDA 1YYTA 3BNXA 3V66A 2J1PA 5KSXF 5AHUB 3WJNA 2ZEVA 4KQSA 4KQUA 3ZCDA 1JFAA 3KRAB 5DGMF 2F8CF 5E8HA 3LVSA 5EATA 3TFVA 4NG6A 5B03A 3NPKA 3KROB 2Z50A 3Q2ZA 4L2XF 3WSAA 3ZMCA 3ZL6A 4KVWA 5ER8A 5HN8A 3M02A 4RXDA 3TFNA 4F6VA 1UBVA 3P8LA 5ERNA 3G4FA 5JUZF 3WCCA 4XQRF 3N6KF 3WCGA 3N1WF 2E92A 5IMIA 3Q2QA 2PS7A 5E8KA 5B0KA 1YHLA 5IKAA 1RQIA 3CKEA 3SDQA 5B00A 3ZMBA 1UBXA 3WCAA 1HXAA 3AQBB 4E1EA 3LJIA 5C05A 2E90A 2AZKA 3QQVA 3KRCA 1DGPA 3ID0A 3RMGA 4KPDA 4LUUA 4JXYA 3ZOUA 4LPHF 3APZA 5IK0A 1WMWA 4KWDA 4QXSF 2PS5A 5B0JA 3W7FA 4DI5A 5B0IA 1KIZA 3N3DA 1V4EA 3IBAA 5H9DA 3VJAA 1FPSA 3WCHA 1N23A 4Q23A 3EFQA 5EAUA 3EZ3A 1YYRA 5IM1A 2E91A 3N5JF 5B0LA 4DXJA 4KKMA 2E8TA 1V4HA 4H5DF 2F9KF 3WC9A 1WL1A 5IMPA 2F92F 3S9VA 1HX9A 2E8XA 4E9ZA 3VJDA 1YQ7A 3VJBA 4ZQ8A 4EA2A 5HN9A 3BNYA 1VG3A 4JZBA 4LTVA 4LA5A 3WE9A 4DWBA 4OKZA 5ILKA 1RQJA 2Z4XA 3EGTA 4PVXF 5ILJA 2EWGA 3WCBA 3VJEA 1N20A 3ADZA 3SDRA 5JV2F 3WCDA 3ICMA 5JV0F 5ERMA 3WJOA 1YYSA 3KRFB 1N22A 4FJQA 5AELA 4EA1A 5IL8A 1ZW5A 4QPFA 3IPIA 4GP2A 4LTZA 3N46F 3WEFA 2E8VA 3DYHA 4LZ0A 5IL3A 3Q1OA 4RXCA 2Z4YA 4KUXA 5DHKA 3N0FA 3PYAA 2PS8A 5CG5A 4OMGA 3AQCB 3KRPA 5IVGA 4NFJF 5ILYA 4LA6A 5DJRF 5CG6A 4RNQA 2F89F 3SDVA 4OGUA 3PKOA 2QISA 3N3LF 2AZLA 3OYRA 5EASA 1WY0A 2Q58A 3WSBA 3NRIA 1UBYA 2Z52A 5IK9A 4MC0A 4KVYA 3KROA 5IMNA 1UBWA 3AE0A 5DJPF 3WJKA 2Z4ZA 5IK6A 2Z7HA 3KRCB 3WCLA 3P5RA 4LFEA 1N21A 3ASXA 3NF2A 1YHKA 1VG7A 2AEKA 1WL0A 3PYBA 3SAEA 3LK5A 3TFPA 1DI1A 3ACXA 5IN8A 2E94A 5JV1F 2OA6A 5IKHA 4DHDA 2O1OA 4LFGA 4N9UA 3WCIA 3SDTA 2AETA 4LPGF 3LOMA 2ZEUA 4K10A 5DW7A 2Q80A 3B7LA 1VG4A 3N45F 2OPNA 5ILZA 3OACA 3RYEA 1V4JA 5A0JA 5DZ2A 2F94F 3PDEA 3M01A 4N1ZF 2F8ZF 5ILIA 3WCMA 2ZCQA 3P8RA 4RXEA 2Z78A 1JFGA 3VJ8A 4KPJA 4NFIF 2FORA 2Z4WA 3KBKA 1RTRA 3LDWA 3QKCA 4LZCA 3OABA 4WK5A 3ICNA 3M0GA 3WCJA 3WEKA 2ZCOA 5HNAA 4LIXA 4JYXA 3KB9A 3AQ0A 4GAXA 4FP4A 3LGZB 1WL3A 4PVYF 1YHMA 4LLTA 3ICZA 4NUAA 3WEIA 1EZFA 1PS1A 1WL2A 3DYGA 4H5EF 3RBMA 4P0XA 5A0KA 4P0WA 3LMDA 3P5PA 5DJVF 4JZXA 4KK2A 1N1BA 2AELA 3M00A 4NFKF 2E8WA 2P1CA 3LGKA 4KVDA 4KQ5A 3VJCA 3MZVA 4HD1A 3LG5A 3M9UA 3NPRA 4DWGA 4F62A 2Q9YA 2Z7IA 3KRPB 3CP6A 5B0MA 4LLSA 3RYWA 2F7MF 3ACWA 3Q30A 3KRFA 5HN7A 1HM7A 3LLWA 5AFXA 5JA0F
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5AYP A;  3KRA A;  4NKF A;  1WKZ A;  3ICK A;  4LFV F;  4UMJ A;  4XQT F;  5DGS F;  1HXC A;  3LSN A;  4NKE A;  5DHI A;  2PS6 A;  2J1O A;  1YJ4 A;  3VJ9 A;  5DGN F;  4MC8 A;  4H5C F;  4MC3 A;  4F6X A;  2ONH A;  2ONG A;  4DZW A;  4XQS F;  5A0I A;  4KFA A;  2AZJ A;  5I1U A;  1N1Z A;  1YV5 A;  4LOB A;  1VG6 A;  2E8U A;  1YYQ A;  2PS4 A;  4JXN A;  3WEH A;  3LZ9 A;  5DIQ F;  3TS7 A;  3S4J A;  5B02 A;  1V4I A;  2E4O A;  3OAC B;  4EA0 A;  3V1X A;  4RXA A;  2J5C A;  3LEE A;  4OKM A;  4KVI A;  4LZ3 A;  3WCF A;  4P0V A;  2E95 A;  2DH4 A;  2E93 A;  3N5H F;  2H8O A;  3N49 F;  3OAB B;  2I19 A;  4LXW A;  3ACY A;  1VG2 A;  3UCA A;  4RYP A;  2VF6 A;  3P41 A;  2ZCR A;  1V4K A;  3CC9 A;  4OMH A;  2Z4V A;  2ZY1 A;  3DYF A;  4E9U A;  5B01 A;  3G4D A;  1KIY A;  3SDU A;  3V1V A;  3WEJ A;  2FTZ A;  3N1V F;  3WEG A;  5E8L A;  1N24 A;  1HM4 A;  3WCE A;  3MAV A;  2Q9Z A;  2OPM A;  1HXG A;  4DEM F;  4GA3 A;  2ZCS A;  3TC1 A;  2RAH A;  1YYU A;  5ILD A;  5ILH A;  4GP1 A;  3N0G A;  3PH7 A;  4JVJ F;  5ERO A;  2OGD A;  1YYT A;  3BNX A;  3V66 A;  2J1P A;  5KSX F;  5AHU B;  3WJN A;  2ZEV A;  4KQS A;  4KQU A;  3ZCD A;  1JFA A;  3KRA B;  5DGM F;  2F8C F;  5E8H A;  3LVS A;  5EAT A;  3TFV A;  4NG6 A;  5B03 A;  3NPK A;  3KRO B;  2Z50 A;  3Q2Z A;  4L2X F;  3WSA A;  3ZMC A;  3ZL6 A;  4KVW A;  5ER8 A;  5HN8 A;  3M02 A;  4RXD A;  3TFN A;  4F6V A;  1UBV A;  3P8L A;  5ERN A;  3G4F A;  5JUZ F;  3WCC A;  4XQR F;  3N6K F;  3WCG A;  3N1W F;  2E92 A;  5IMI A;  3Q2Q A;  2PS7 A;  5E8K A;  5B0K A;  1YHL A;  5IKA A;  1RQI A;  3CKE A;  3SDQ A;  5B00 A;  3ZMB A;  1UBX A;  3WCA A;  1HXA A;  3AQB B;  4E1E A;  3LJI A;  5C05 A;  2E90 A;  2AZK A;  3QQV A;  3KRC A;  1DGP A;  3ID0 A;  3RMG A;  4KPD A;  4LUU A;  4JXY A;  3ZOU A;  4LPH F;  3APZ A;  5IK0 A;  1WMW A;  4KWD A;  4QXS F;  2PS5 A;  5B0J A;  3W7F A;  4DI5 A;  5B0I A;  1KIZ A;  3N3D A;  1V4E A;  3IBA A;  5H9D A;  3VJA A;  1FPS A;  3WCH A;  1N23 A;  4Q23 A;  3EFQ A;  5EAU A;  3EZ3 A;  1YYR A;  5IM1 A;  2E91 A;  3N5J F;  5B0L A;  4DXJ A;  4KKM A;  2E8T A;  1V4H A;  4H5D F;  2F9K F;  3WC9 A;  1WL1 A;  5IMP A;  2F92 F;  3S9V A;  1HX9 A;  2E8X A;  4E9Z A;  3VJD A;  1YQ7 A;  3VJB A;  4ZQ8 A;  4EA2 A;  5HN9 A;  3BNY A;  1VG3 A;  4JZB A;  4LTV A;  4LA5 A;  3WE9 A;  4DWB A;  4OKZ A;  5ILK A;  1RQJ A;  2Z4X A;  3EGT A;  4PVX F;  5ILJ A;  2EWG A;  3WCB A;  3VJE A;  1N20 A;  3ADZ A;  3SDR A;  5JV2 F;  3WCD A;  3ICM A;  5JV0 F;  5ERM A;  3WJO A;  1YYS A;  3KRF B;  1N22 A;  4FJQ A;  5AEL A;  4EA1 A;  5IL8 A;  1ZW5 A;  4QPF A;  3IPI A;  4GP2 A;  4LTZ A;  3N46 F;  3WEF A;  2E8V A;  3DYH A;  4LZ0 A;  5IL3 A;  3Q1O A;  4RXC A;  2Z4Y A;  4KUX A;  5DHK A;  3N0F A;  3PYA A;  2PS8 A;  5CG5 A;  4OMG A;  3AQC B;  3KRP A;  5IVG A;  4NFJ F;  5ILY A;  4LA6 A;  5DJR F;  5CG6 A;  4RNQ A;  2F89 F;  3SDV A;  4OGU A;  3PKO A;  2QIS A;  3N3L F;  2AZL A;  3OYR A;  5EAS A;  1WY0 A;  2Q58 A;  3WSB A;  3NRI A;  1UBY A;  2Z52 A;  5IK9 A;  4MC0 A;  4KVY A;  3KRO A;  5IMN A;  1UBW A;  3AE0 A;  5DJP F;  3WJK A;  2Z4Z A;  5IK6 A;  2Z7H A;  3KRC B;  3WCL A;  3P5R A;  4LFE A;  1N21 A;  3ASX A;  3NF2 A;  1YHK A;  1VG7 A;  2AEK A;  1WL0 A;  3PYB A;  3SAE A;  3LK5 A;  3TFP A;  1DI1 A;  3ACX A;  5IN8 A;  2E94 A;  5JV1 F;  2OA6 A;  5IKH A;  4DHD A;  2O1O A;  4LFG A;  4N9U A;  3WCI A;  3SDT A;  2AET A;  4LPG F;  3LOM A;  2ZEU A;  4K10 A;  5DW7 A;  2Q80 A;  3B7L A;  1VG4 A;  3N45 F;  2OPN A;  5ILZ A;  3OAC A;  3RYE A;  1V4J A;  5A0J A;  5DZ2 A;  2F94 F;  3PDE A;  3M01 A;  4N1Z F;  2F8Z F;  5ILI A;  3WCM A;  2ZCQ A;  3P8R A;  4RXE A;  2Z78 A;  1JFG A;  3VJ8 A;  4KPJ A;  4NFI F;  2FOR A;  2Z4W A;  3KBK A;  1RTR A;  3LDW A;  3QKC A;  4LZC A;  3OAB A;  4WK5 A;  3ICN A;  3M0G A;  3WCJ A;  3WEK A;  2ZCO A;  5HNA A;  4LIX A;  4JYX A;  3KB9 A;  3AQ0 A;  4GAX A;  4FP4 A;  3LGZ B;  1WL3 A;  4PVY F;  1YHM A;  4LLT A;  3ICZ A;  4NUA A;  3WEI A;  1EZF A;  1PS1 A;  1WL2 A;  3DYG A;  4H5E F;  3RBM A;  4P0X A;  5A0K A;  4P0W A;  3LMD A;  3P5P A;  5DJV F;  4JZX A;  4KK2 A;  1N1B A;  2AEL A;  3M00 A;  4NFK F;  2E8W A;  2P1C A;  3LGK A;  4KVD A;  4KQ5 A;  3VJC A;  3MZV A;  4HD1 A;  3LG5 A;  3M9U A;  3NPR A;  4DWG A;  4F62 A;  2Q9Y A;  2Z7I A;  3KRP B;  3CP6 A;  5B0M A;  4LLS A;  3RYW A;  2F7M F;  3ACW A;  3Q30 A;  3KRF A;  5HN7 A;  1HM7 A;  3LLW A;  5AFX A;  5JA0 F; 
#chains in the Genus database with same CATH topology
 5AYP A;  3KRA A;  4NKF A;  1WKZ A;  3ICK A;  4LFV F;  4UMJ A;  4XQT F;  5DGS F;  1HXC A;  3LSN A;  4NKE A;  5DHI A;  2PS6 A;  2J1O A;  1YJ4 A;  3VJ9 A;  5DGN F;  4MC8 A;  4H5C F;  4MC3 A;  4F6X A;  2ONH A;  2ONG A;  4DZW A;  4XQS F;  5A0I A;  4KFA A;  2AZJ A;  5I1U A;  1N1Z A;  1YV5 A;  4LOB A;  1VG6 A;  2E8U A;  1YYQ A;  2PS4 A;  4JXN A;  3WEH A;  3LZ9 A;  5DIQ F;  3TS7 A;  3S4J A;  5B02 A;  1V4I A;  2E4O A;  3OAC B;  4EA0 A;  3V1X A;  4RXA A;  2J5C A;  3LEE A;  4OKM A;  4KVI A;  4LZ3 A;  3WCF A;  4P0V A;  2E95 A;  2DH4 A;  2E93 A;  3N5H F;  2H8O A;  3N49 F;  3OAB B;  2I19 A;  4LXW A;  3ACY A;  1VG2 A;  3UCA A;  4RYP A;  2VF6 A;  3P41 A;  2ZCR A;  1V4K A;  3CC9 A;  4OMH A;  2Z4V A;  2ZY1 A;  3DYF A;  4E9U A;  5B01 A;  3G4D A;  1KIY A;  3SDU A;  3V1V A;  3WEJ A;  2FTZ A;  3N1V F;  3WEG A;  5E8L A;  1N24 A;  1HM4 A;  3WCE A;  3MAV A;  2Q9Z A;  2OPM A;  1HXG A;  4DEM F;  4GA3 A;  2ZCS A;  3TC1 A;  2RAH A;  1YYU A;  5ILD A;  5ILH A;  4GP1 A;  3N0G A;  3PH7 A;  4JVJ F;  5ERO A;  2OGD A;  1YYT A;  3BNX A;  3V66 A;  2J1P A;  5KSX F;  5AHU B;  3WJN A;  2ZEV A;  4KQS A;  4KQU A;  3ZCD A;  1JFA A;  3KRA B;  5DGM F;  2F8C F;  5E8H A;  3LVS A;  5EAT A;  3TFV A;  4NG6 A;  5B03 A;  3NPK A;  3KRO B;  2Z50 A;  3Q2Z A;  4L2X F;  3WSA A;  3ZMC A;  3ZL6 A;  4KVW A;  5ER8 A;  5HN8 A;  3M02 A;  4RXD A;  3TFN A;  4F6V A;  1UBV A;  3P8L A;  5ERN A;  3G4F A;  5JUZ F;  3WCC A;  4XQR F;  3N6K F;  3WCG A;  3N1W F;  2E92 A;  5IMI A;  3Q2Q A;  2PS7 A;  5E8K A;  5B0K A;  1YHL A;  5IKA A;  1RQI A;  3CKE A;  3SDQ A;  5B00 A;  3ZMB A;  1UBX A;  3WCA A;  1HXA A;  3AQB B;  4E1E A;  3LJI A;  5C05 A;  2E90 A;  2AZK A;  3QQV A;  3KRC A;  1DGP A;  3ID0 A;  3RMG A;  4KPD A;  4LUU A;  4JXY A;  3ZOU A;  4LPH F;  3APZ A;  5IK0 A;  1WMW A;  4KWD A;  4QXS F;  2PS5 A;  5B0J A;  3W7F A;  4DI5 A;  5B0I A;  1KIZ A;  3N3D A;  1V4E A;  3IBA A;  5H9D A;  3VJA A;  1FPS A;  3WCH A;  1N23 A;  4Q23 A;  3EFQ A;  5EAU A;  3EZ3 A;  1YYR A;  5IM1 A;  2E91 A;  3N5J F;  5B0L A;  4DXJ A;  4KKM A;  2E8T A;  1V4H A;  4H5D F;  2F9K F;  3WC9 A;  1WL1 A;  5IMP A;  2F92 F;  3S9V A;  1HX9 A;  2E8X A;  4E9Z A;  3VJD A;  1YQ7 A;  3VJB A;  4ZQ8 A;  4EA2 A;  5HN9 A;  3BNY A;  1VG3 A;  4JZB A;  4LTV A;  4LA5 A;  3WE9 A;  4DWB A;  4OKZ A;  5ILK A;  1RQJ A;  2Z4X A;  3EGT A;  4PVX F;  5ILJ A;  2EWG A;  3WCB A;  3VJE A;  1N20 A;  3ADZ A;  3SDR A;  5JV2 F;  3WCD A;  3ICM A;  5JV0 F;  5ERM A;  3WJO A;  1YYS A;  3KRF B;  1N22 A;  4FJQ A;  5AEL A;  4EA1 A;  5IL8 A;  1ZW5 A;  4QPF A;  3IPI A;  4GP2 A;  4LTZ A;  3N46 F;  3WEF A;  2E8V A;  3DYH A;  4LZ0 A;  5IL3 A;  3Q1O A;  4RXC A;  2Z4Y A;  4KUX A;  5DHK A;  3N0F A;  3PYA A;  2PS8 A;  5CG5 A;  4OMG A;  3AQC B;  3KRP A;  5IVG A;  4NFJ F;  5ILY A;  4LA6 A;  5DJR F;  5CG6 A;  4RNQ A;  2F89 F;  3SDV A;  4OGU A;  3PKO A;  2QIS A;  3N3L F;  2AZL A;  3OYR A;  5EAS A;  1WY0 A;  2Q58 A;  3WSB A;  3NRI A;  1UBY A;  2Z52 A;  5IK9 A;  4MC0 A;  4KVY A;  3KRO A;  5IMN A;  1UBW A;  3AE0 A;  5DJP F;  3WJK A;  2Z4Z A;  5IK6 A;  2Z7H A;  3KRC B;  3WCL A;  3P5R A;  4LFE A;  1N21 A;  3ASX A;  3NF2 A;  1YHK A;  1VG7 A;  2AEK A;  1WL0 A;  3PYB A;  3SAE A;  3LK5 A;  3TFP A;  1DI1 A;  3ACX A;  5IN8 A;  2E94 A;  5JV1 F;  2OA6 A;  5IKH A;  4DHD A;  2O1O A;  4LFG A;  4N9U A;  3WCI A;  3SDT A;  2AET A;  4LPG F;  3LOM A;  2ZEU A;  4K10 A;  5DW7 A;  2Q80 A;  3B7L A;  1VG4 A;  3N45 F;  2OPN A;  5ILZ A;  3OAC A;  3RYE A;  1V4J A;  5A0J A;  5DZ2 A;  2F94 F;  3PDE A;  3M01 A;  4N1Z F;  2F8Z F;  5ILI A;  3WCM A;  2ZCQ A;  3P8R A;  4RXE A;  2Z78 A;  1JFG A;  3VJ8 A;  4KPJ A;  4NFI F;  2FOR A;  2Z4W A;  3KBK A;  1RTR A;  3LDW A;  3QKC A;  4LZC A;  3OAB A;  4WK5 A;  3ICN A;  3M0G A;  3WCJ A;  3WEK A;  2ZCO A;  5HNA A;  4LIX A;  4JYX A;  3KB9 A;  3AQ0 A;  4GAX A;  4FP4 A;  3LGZ B;  1WL3 A;  4PVY F;  1YHM A;  4LLT A;  3ICZ A;  4NUA A;  3WEI A;  1EZF A;  1PS1 A;  1WL2 A;  3DYG A;  4H5E F;  3RBM A;  4P0X A;  5A0K A;  4P0W A;  3LMD A;  3P5P A;  5DJV F;  4JZX A;  4KK2 A;  1N1B A;  2AEL A;  3M00 A;  4NFK F;  2E8W A;  2P1C A;  3LGK A;  4KVD A;  4KQ5 A;  3VJC A;  3MZV A;  4HD1 A;  3LG5 A;  3M9U A;  3NPR A;  4DWG A;  4F62 A;  2Q9Y A;  2Z7I A;  3KRP B;  3CP6 A;  5B0M A;  4LLS A;  3RYW A;  2F7M F;  3ACW A;  3Q30 A;  3KRF A;  5HN7 A;  1HM7 A;  3LLW A;  5AFX A;  5JA0 F; 
#chains in the Genus database with same CATH homology
 5AYP A;  3KRA A;  4NKF A;  1WKZ A;  3ICK A;  4LFV F;  4UMJ A;  4XQT F;  5DGS F;  1HXC A;  3LSN A;  4NKE A;  5DHI A;  2PS6 A;  2J1O A;  1YJ4 A;  3VJ9 A;  5DGN F;  4MC8 A;  4H5C F;  4MC3 A;  4F6X A;  2ONH A;  2ONG A;  4DZW A;  4XQS F;  5A0I A;  4KFA A;  2AZJ A;  5I1U A;  1N1Z A;  1YV5 A;  4LOB A;  1VG6 A;  2E8U A;  1YYQ A;  2PS4 A;  4JXN A;  3WEH A;  3LZ9 A;  5DIQ F;  3TS7 A;  3S4J A;  5B02 A;  1V4I A;  2E4O A;  3OAC B;  4EA0 A;  3V1X A;  4RXA A;  2J5C A;  3LEE A;  4OKM A;  4KVI A;  4LZ3 A;  3WCF A;  4P0V A;  2E95 A;  2DH4 A;  2E93 A;  3N5H F;  2H8O A;  3N49 F;  3OAB B;  2I19 A;  4LXW A;  3ACY A;  1VG2 A;  3UCA A;  4RYP A;  2VF6 A;  3P41 A;  2ZCR A;  1V4K A;  3CC9 A;  4OMH A;  2Z4V A;  2ZY1 A;  3DYF A;  4E9U A;  5B01 A;  3G4D A;  1KIY A;  3SDU A;  3V1V A;  3WEJ A;  2FTZ A;  3N1V F;  3WEG A;  5E8L A;  1N24 A;  1HM4 A;  3WCE A;  3MAV A;  2Q9Z A;  2OPM A;  1HXG A;  4DEM F;  4GA3 A;  2ZCS A;  3TC1 A;  2RAH A;  1YYU A;  5ILD A;  5ILH A;  4GP1 A;  3N0G A;  3PH7 A;  4JVJ F;  5ERO A;  2OGD A;  1YYT A;  3BNX A;  3V66 A;  2J1P A;  5KSX F;  5AHU B;  3WJN A;  2ZEV A;  4KQS A;  4KQU A;  3ZCD A;  1JFA A;  3KRA B;  5DGM F;  2F8C F;  5E8H A;  3LVS A;  5EAT A;  3TFV A;  4NG6 A;  5B03 A;  3NPK A;  3KRO B;  2Z50 A;  3Q2Z A;  4L2X F;  3WSA A;  3ZMC A;  3ZL6 A;  4KVW A;  5ER8 A;  5HN8 A;  3M02 A;  4RXD A;  3TFN A;  4F6V A;  1UBV A;  3P8L A;  5ERN A;  3G4F A;  5JUZ F;  3WCC A;  4XQR F;  3N6K F;  3WCG A;  3N1W F;  2E92 A;  5IMI A;  3Q2Q A;  2PS7 A;  5E8K A;  5B0K A;  1YHL A;  5IKA A;  1RQI A;  3CKE A;  3SDQ A;  5B00 A;  3ZMB A;  1UBX A;  3WCA A;  1HXA A;  3AQB B;  4E1E A;  3LJI A;  5C05 A;  2E90 A;  2AZK A;  3QQV A;  3KRC A;  1DGP A;  3ID0 A;  3RMG A;  4KPD A;  4LUU A;  4JXY A;  3ZOU A;  4LPH F;  3APZ A;  5IK0 A;  1WMW A;  4KWD A;  4QXS F;  2PS5 A;  5B0J A;  3W7F A;  4DI5 A;  5B0I A;  1KIZ A;  3N3D A;  1V4E A;  3IBA A;  5H9D A;  3VJA A;  1FPS A;  3WCH A;  1N23 A;  4Q23 A;  3EFQ A;  5EAU A;  3EZ3 A;  1YYR A;  5IM1 A;  2E91 A;  3N5J F;  5B0L A;  4DXJ A;  4KKM A;  2E8T A;  1V4H A;  4H5D F;  2F9K F;  3WC9 A;  1WL1 A;  5IMP A;  2F92 F;  3S9V A;  1HX9 A;  2E8X A;  4E9Z A;  3VJD A;  1YQ7 A;  3VJB A;  4ZQ8 A;  4EA2 A;  5HN9 A;  3BNY A;  1VG3 A;  4JZB A;  4LTV A;  4LA5 A;  3WE9 A;  4DWB A;  4OKZ A;  5ILK A;  1RQJ A;  2Z4X A;  3EGT A;  4PVX F;  5ILJ A;  2EWG A;  3WCB A;  3VJE A;  1N20 A;  3ADZ A;  3SDR A;  5JV2 F;  3WCD A;  3ICM A;  5JV0 F;  5ERM A;  3WJO A;  1YYS A;  3KRF B;  1N22 A;  4FJQ A;  5AEL A;  4EA1 A;  5IL8 A;  1ZW5 A;  4QPF A;  3IPI A;  4GP2 A;  4LTZ A;  3N46 F;  3WEF A;  2E8V A;  3DYH A;  4LZ0 A;  5IL3 A;  3Q1O A;  4RXC A;  2Z4Y A;  4KUX A;  5DHK A;  3N0F A;  3PYA A;  2PS8 A;  5CG5 A;  4OMG A;  3AQC B;  3KRP A;  5IVG A;  4NFJ F;  5ILY A;  4LA6 A;  5DJR F;  5CG6 A;  4RNQ A;  2F89 F;  3SDV A;  4OGU A;  3PKO A;  2QIS A;  3N3L F;  2AZL A;  3OYR A;  5EAS A;  1WY0 A;  2Q58 A;  3WSB A;  3NRI A;  1UBY A;  2Z52 A;  5IK9 A;  4MC0 A;  4KVY A;  3KRO A;  5IMN A;  1UBW A;  3AE0 A;  5DJP F;  3WJK A;  2Z4Z A;  5IK6 A;  2Z7H A;  3KRC B;  3WCL A;  3P5R A;  4LFE A;  1N21 A;  3ASX A;  3NF2 A;  1YHK A;  1VG7 A;  2AEK A;  1WL0 A;  3PYB A;  3SAE A;  3LK5 A;  3TFP A;  1DI1 A;  3ACX A;  5IN8 A;  2E94 A;  5JV1 F;  2OA6 A;  5IKH A;  4DHD A;  2O1O A;  4LFG A;  4N9U A;  3WCI A;  3SDT A;  2AET A;  4LPG F;  3LOM A;  2ZEU A;  4K10 A;  5DW7 A;  2Q80 A;  3B7L A;  1VG4 A;  3N45 F;  2OPN A;  5ILZ A;  3OAC A;  3RYE A;  1V4J A;  5A0J A;  5DZ2 A;  2F94 F;  3PDE A;  3M01 A;  4N1Z F;  2F8Z F;  5ILI A;  3WCM A;  2ZCQ A;  3P8R A;  4RXE A;  2Z78 A;  1JFG A;  3VJ8 A;  4KPJ A;  4NFI F;  2FOR A;  2Z4W A;  3KBK A;  1RTR A;  3LDW A;  3QKC A;  4LZC A;  3OAB A;  4WK5 A;  3ICN A;  3M0G A;  3WCJ A;  3WEK A;  2ZCO A;  5HNA A;  4LIX A;  4JYX A;  3KB9 A;  3AQ0 A;  4GAX A;  4FP4 A;  3LGZ B;  1WL3 A;  4PVY F;  1YHM A;  4LLT A;  3ICZ A;  4NUA A;  3WEI A;  1EZF A;  1PS1 A;  1WL2 A;  3DYG A;  4H5E F;  3RBM A;  4P0X A;  5A0K A;  4P0W A;  3LMD A;  3P5P A;  5DJV F;  4JZX A;  4KK2 A;  1N1B A;  2AEL A;  3M00 A;  4NFK F;  2E8W A;  2P1C A;  3LGK A;  4KVD A;  4KQ5 A;  3VJC A;  3MZV A;  4HD1 A;  3LG5 A;  3M9U A;  3NPR A;  4DWG A;  4F62 A;  2Q9Y A;  2Z7I A;  3KRP B;  3CP6 A;  5B0M A;  4LLS A;  3RYW A;  2F7M F;  3ACW A;  3Q30 A;  3KRF A;  5HN7 A;  1HM7 A;  3LLW A;  5AFX A;  5JA0 F; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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