4NG6A

The effects of lysine 200 and phenylalanine 239 farnesyl pyrophosphate synthase (fpps) mutations on the catalytic activity, crystal structure and inhibition by nitrogen containing bisphosphonates
Total Genus 131
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
131
sequence length
344
structure length
344
Chain Sequence
YAQEKQDFVQHFSQIVRVLTEDEMGHPEIGDAIARLKEVLEYNAIGGKYNRGLTVVVAFRELVEPRKQDADSLQRAWTVGWCVELLQAFFLVADDIMDSSLTRRGQICWYQKPGVGLDAINDANLLEACIYRLLKLYCREQPYYLNLIELFLQSSYQTEIGQTLDLLTAPQGNVDLVRFTEKRYKSIVKYLTAFYSFYLPIAAAMYMAGIDGEKEHANAKKILLEMGEFFQIQDDYLDLFGDPSVTGKIGTDIQDNKCSWLVVQCLQRATPEQYQILKENYGQKEAEKVARVKALYEELDLPAVFLQYEEDSYSHIMALIEQYAAPLPPAVFLGLARKIYKRRK
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The effects of Lysine 200 and Phenylalanine 239 Farnesyl Pyrophosphate Synthase (FPPS) mutations on the catalytic activity, crystal structure and inhibition by nitrogen containing bisphosphonates
rcsb
molecule tags Transferase
source organism Homo sapiens
molecule keywords Farnesyl pyrophosphate synthase
total genus 131
structure length 344
sequence length 344
ec nomenclature ec 2.5.1.1: Dimethylallyltranstransferase.
pdb deposition date 2013-11-01

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00348 polyprenyl_synt Polyprenyl synthetase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.600.10 Mainly Alpha Orthogonal Bundle Farnesyl Diphosphate Synthase Farnesyl Diphosphate Synthase 4ng6A00
3KB9A 5ILKA 5DHIA 3M9UA 5I1UA 3WCBA 3Q2QA 3KRPB 4ZQ8A 1DI1A 4LA5A 3ZOUA 5DJRF 4P0WA 1WL0A 2Z7IA 4LXWA 4KVWA 1N20A 3LSNA 1WMWA 4FP4A 2EWGA 3CP6A 2Q9ZA 3WCHA 3AQ0A 4NKFA 1N1BA 5HN8A 2FTZA 2ZCRA 4QXSF 3RYEA 3DYHA 2F94F 1RTRA 2E95A 3WCDA 5B0JA 2F89F 3OABB 3WJKA 4E9ZA 5IMPA 4DZWA 2Z78A 1HX9A 3Q1OA 4RXEA 5IVGA 5B0KA 1WKZA 1YQ7A 5DGNF 3WSAA 3BNYA 4KQ5A 4PVYF 3M01A 5AELA 3TFPA 3ZMBA 4KKMA 4LPGF 2ZEUA 5ILHA 2AETA 4N1ZF 3KRFA 4LLSA 4KVIA 3MAVA 3N6KF 5EAUA 4JYXA 4P0XA 2ONHA 3KRCA 5CG6A 3DYGA 4H5CF 4OGUA 1VG2A 2F92F 1YHKA 2AZKA 1HM7A 2H8OA 2PS8A 4LIXA 2OGDA 4DWGA 4E9UA 3V1VA 3WEFA 4XQTF 3N0GA 3ICZA 3N45F 3LEEA 2PS6A 2E8TA 4EA1A 3PYAA 3SAEA 4DEMF 3PH7A 1V4JA 3Q2ZA 5IL8A 3ZMCA 1V4IA 3RYWA 3G4FA 1N21A 3WEKA 5IK6A 1V4EA 5IK9A 3BNXA 3EFQA 5CG5A 3WE9A 3WCFA 3ACXA 4GP2A 3OYRA 5DHKA 3VJEA 3V1XA 4DXJA 2I19A 3S9VA 2ZCQA 5DJVF 4NFJF 3LDWA 1HXCA 3M02A 5IMNA 3WCJA 1YV5A 2E92A 2AZLA 4LFGA 3NF2A 3KRAB 2E8XA 3SDTA 2AELA 2OPMA 3EGTA 2QISA 3IBAA 5HN7A 5E8HA 1WL3A 3ID0A 1YHMA 5B03A 3KRFB 3P41A 3VJBA 5E8LA 1N22A 1YHLA 2Q58A 3LVSA 2F8CF 5HN9A 4PVXF 3SDUA 1YYTA 3KRCB 4H5EF 1JFAA 2OPNA 2Z50A 1WY0A 3WEIA 4KVYA 4Q23A 3VJ8A 3P8RA 5ILJA 3WCCA 3LJIA 2VF6A 4XQSF 2O1OA 5IMIA 5C05A 3NPKA 2DH4A 3LOMA 1PS1A 5JV1F 4L2XF 5B00A 2ZEVA 1V4KA 4LTVA 3TS7A 2AEKA 4N9UA 3LZ9A 2J5CA 3TFNA 4OKZA 1KIYA 2E8VA 5ERMA 3B7LA 4KQUA 1YYRA 4OMHA 3KRPA 5JUZF 3ICKA 5IM1A 3SDQA 1VG4A 3ICNA 3WJOA 5ILYA 5B0MA 3WCIA 5KSXF 3P8LA 1VG6A 2Z4XA 4OKMA 1UBWA 5H9DA 4LZCA 5AHUB 5B0IA 3P5PA 4GAXA 2Q80A 3N3DA 1VG7A 4LLTA 4LTZA 1DGPA 4EA0A 3KROA 3VJAA 3N1WF 5ILZA 5DGMF 5A0KA 3NPRA 2AZJA 2E91A 1UBYA 4KFAA 4UMJA 5AFXA 4NUAA 1WL1A 1WL2A 4JXYA 2E90A 5AYPA 5DGSF 2PS5A 3AQCB 3ACYA 3ICMA 3WCLA 3ACWA 4RXAA 4HD1A 5E8KA 4JVJF 5IN8A 4LUUA 3WCMA 4NFIF 1RQIA 5IKHA 3WEHA 3LGKA 5ER8A 2PS7A 2Q9YA 3ASXA 3AE0A 2Z7HA 3RBMA 4JXNA 2J1OA 4DHDA 3MZVA 4LFEA 3WJNA 3OACA 3ZCDA 4KQSA 4KPDA 3VJ9A 2F9KF 2PS4A 3G4DA 3N1VF 4MC8A 2Z4WA 4JZXA 5A0JA 1RQJA 4KK2A 5DIQF 3WCGA 4KWDA 5JA0F 1UBXA 5IKAA 4E1EA 5B0LA 1KIZA 2Z4VA 2E8UA 1ZW5A 2E8WA 1HXAA 5JV0F 3PDEA 5JV2F 1YJ4A 2J1PA 1JFGA 5IK0A 4P0VA 3LK5A 5EATA 4DWBA 5B02A 1YYSA 3EZ3A 3SDVA 4OMGA 3DYFA 3KROB 3WCEA 4KPJA 5A0IA 1HM4A 1YYUA 3W7FA 4F6XA 4RNQA 2ONGA 3WEJA 3WSBA 3M0GA 1N23A 3KRAA 5DW7A 1EZFA 3ZL6A 4LOBA 3RMGA 3N0FA 2F8ZF 3UCAA 3SDRA 4EA2A 4F62A 2Z52A 4XQRF 2ZY1A 3LGZB 3ADZA 5HNAA 4K10A 5B01A 3TC1A 5ERNA 3M00A 1V4HA 3N5JF 2ZCOA 4F6VA 3AQBB 5EASA 3NRIA 5DJPF 3CC9A 3N49F 3CKEA 3OABA 3IPIA 4LA6A 3S4JA 1UBVA 2E94A 4KUXA 3VJCA 3WCAA 1YYQA 3PKOA 4NG6A 3VJDA 3OACB 3KBKA 2P1CA 4MC3A 2Z4YA 2Z4ZA 3LLWA 4RXDA 4GP1A 1FPSA 4LPHF 4LZ3A 3N5HF 2E4OA 4NFKF 5EROA 1VG3A 4NKEA 4RXCA 5DZ2A 3LMDA 1N24A 2F7MF 4JZBA 1N1ZA 5ILIA 3N3LF 4QPFA 2RAHA 2OA6A 4WK5A 4DI5A 3N46F 4LFVF 5IL3A 3APZA 3PYBA 3WEGA 3V66A 4RYPA 3P5RA 3QKCA 3WC9A 3QQVA 4H5DF 5ILDA 2E93A 4LZ0A 4GA3A 4KVDA 3Q30A 4FJQA 1HXGA 2ZCSA 2FORA 4MC0A 3LG5A 3TFVA
chains in the Genus database with same CATH superfamily
3KB9A 5ILKA 5DHIA 3M9UA 5I1UA 3WCBA 3Q2QA 3KRPB 4ZQ8A 1DI1A 4LA5A 3ZOUA 5DJRF 4P0WA 1WL0A 2Z7IA 4LXWA 4KVWA 1N20A 3LSNA 1WMWA 4FP4A 2EWGA 3CP6A 2Q9ZA 3WCHA 3AQ0A 4NKFA 1N1BA 5HN8A 2FTZA 2ZCRA 4QXSF 3RYEA 3DYHA 2F94F 1RTRA 2E95A 3WCDA 5B0JA 2F89F 3OABB 3WJKA 4E9ZA 5IMPA 4DZWA 2Z78A 1HX9A 3Q1OA 4RXEA 5IVGA 5B0KA 1WKZA 1YQ7A 5DGNF 3WSAA 3BNYA 4KQ5A 4PVYF 3M01A 5AELA 3TFPA 3ZMBA 4KKMA 4LPGF 2ZEUA 5ILHA 2AETA 4N1ZF 3KRFA 4LLSA 4KVIA 3MAVA 3N6KF 5EAUA 4JYXA 4P0XA 2ONHA 3KRCA 5CG6A 3DYGA 4H5CF 4OGUA 1VG2A 2F92F 1YHKA 2AZKA 1HM7A 2H8OA 2PS8A 4LIXA 2OGDA 4DWGA 4E9UA 3V1VA 3WEFA 4XQTF 3N0GA 3ICZA 3N45F 3LEEA 2PS6A 2E8TA 4EA1A 3PYAA 3SAEA 4DEMF 3PH7A 1V4JA 3Q2ZA 5IL8A 3ZMCA 1V4IA 3RYWA 3G4FA 1N21A 3WEKA 5IK6A 1V4EA 5IK9A 3BNXA 3EFQA 5CG5A 3WE9A 3WCFA 3ACXA 4GP2A 3OYRA 5DHKA 3VJEA 3V1XA 4DXJA 2I19A 3S9VA 2ZCQA 5DJVF 4NFJF 3LDWA 1HXCA 3M02A 5IMNA 3WCJA 1YV5A 2E92A 2AZLA 4LFGA 3NF2A 3KRAB 2E8XA 3SDTA 2AELA 2OPMA 3EGTA 2QISA 3IBAA 5HN7A 5E8HA 1WL3A 3ID0A 1YHMA 5B03A 3KRFB 3P41A 3VJBA 5E8LA 1N22A 1YHLA 2Q58A 3LVSA 2F8CF 5HN9A 4PVXF 3SDUA 1YYTA 3KRCB 4H5EF 1JFAA 2OPNA 2Z50A 1WY0A 3WEIA 4KVYA 4Q23A 3VJ8A 3P8RA 5ILJA 3WCCA 3LJIA 2VF6A 4XQSF 2O1OA 5IMIA 5C05A 3NPKA 2DH4A 3LOMA 1PS1A 5JV1F 4L2XF 5B00A 2ZEVA 1V4KA 4LTVA 3TS7A 2AEKA 4N9UA 3LZ9A 2J5CA 3TFNA 4OKZA 1KIYA 2E8VA 5ERMA 3B7LA 4KQUA 1YYRA 4OMHA 3KRPA 5JUZF 3ICKA 5IM1A 3SDQA 1VG4A 3ICNA 3WJOA 5ILYA 5B0MA 3WCIA 5KSXF 3P8LA 1VG6A 2Z4XA 4OKMA 1UBWA 5H9DA 4LZCA 5AHUB 5B0IA 3P5PA 4GAXA 2Q80A 3N3DA 1VG7A 4LLTA 4LTZA 1DGPA 4EA0A 3KROA 3VJAA 3N1WF 5ILZA 5DGMF 5A0KA 3NPRA 2AZJA 2E91A 1UBYA 4KFAA 4UMJA 5AFXA 4NUAA 1WL1A 1WL2A 4JXYA 2E90A 5AYPA 5DGSF 2PS5A 3AQCB 3ACYA 3ICMA 3WCLA 3ACWA 4RXAA 4HD1A 5E8KA 4JVJF 5IN8A 4LUUA 3WCMA 4NFIF 1RQIA 5IKHA 3WEHA 3LGKA 5ER8A 2PS7A 2Q9YA 3ASXA 3AE0A 2Z7HA 3RBMA 4JXNA 2J1OA 4DHDA 3MZVA 4LFEA 3WJNA 3OACA 3ZCDA 4KQSA 4KPDA 3VJ9A 2F9KF 2PS4A 3G4DA 3N1VF 4MC8A 2Z4WA 4JZXA 5A0JA 1RQJA 4KK2A 5DIQF 3WCGA 4KWDA 5JA0F 1UBXA 5IKAA 4E1EA 5B0LA 1KIZA 2Z4VA 2E8UA 1ZW5A 2E8WA 1HXAA 5JV0F 3PDEA 5JV2F 1YJ4A 2J1PA 1JFGA 5IK0A 4P0VA 3LK5A 5EATA 4DWBA 5B02A 1YYSA 3EZ3A 3SDVA 4OMGA 3DYFA 3KROB 3WCEA 4KPJA 5A0IA 1HM4A 1YYUA 3W7FA 4F6XA 4RNQA 2ONGA 3WEJA 3WSBA 3M0GA 1N23A 3KRAA 5DW7A 1EZFA 3ZL6A 4LOBA 3RMGA 3N0FA 2F8ZF 3UCAA 3SDRA 4EA2A 4F62A 2Z52A 4XQRF 2ZY1A 3LGZB 3ADZA 5HNAA 4K10A 5B01A 3TC1A 5ERNA 3M00A 1V4HA 3N5JF 2ZCOA 4F6VA 3AQBB 5EASA 3NRIA 5DJPF 3CC9A 3N49F 3CKEA 3OABA 3IPIA 4LA6A 3S4JA 1UBVA 2E94A 4KUXA 3VJCA 3WCAA 1YYQA 3PKOA 4NG6A 3VJDA 3OACB 3KBKA 2P1CA 4MC3A 2Z4YA 2Z4ZA 3LLWA 4RXDA 4GP1A 1FPSA 4LPHF 4LZ3A 3N5HF 2E4OA 4NFKF 5EROA 1VG3A 4NKEA 4RXCA 5DZ2A 3LMDA 1N24A 2F7MF 4JZBA 1N1ZA 5ILIA 3N3LF 4QPFA 2RAHA 2OA6A 4WK5A 4DI5A 3N46F 4LFVF 5IL3A 3APZA 3PYBA 3WEGA 3V66A 4RYPA 3P5RA 3QKCA 3WC9A 3QQVA 4H5DF 5ILDA 2E93A 4LZ0A 4GA3A 4KVDA 3Q30A 4FJQA 1HXGA 2ZCSA 2FORA 4MC0A 3LG5A 3TFVA
chains in the Genus database with same CATH topology
3KB9A 5ILKA 5DHIA 3M9UA 5I1UA 3WCBA 3Q2QA 3KRPB 4ZQ8A 1DI1A 4LA5A 3ZOUA 5DJRF 4P0WA 1WL0A 2Z7IA 4LXWA 4KVWA 1N20A 3LSNA 1WMWA 4FP4A 2EWGA 3CP6A 2Q9ZA 3WCHA 3AQ0A 4NKFA 1N1BA 5HN8A 2FTZA 2ZCRA 4QXSF 3RYEA 3DYHA 2F94F 1RTRA 2E95A 3WCDA 5B0JA 2F89F 3OABB 3WJKA 4E9ZA 5IMPA 4DZWA 2Z78A 1HX9A 3Q1OA 4RXEA 5IVGA 5B0KA 1WKZA 1YQ7A 5DGNF 3WSAA 3BNYA 4KQ5A 4PVYF 3M01A 5AELA 3TFPA 3ZMBA 4KKMA 4LPGF 2ZEUA 5ILHA 2AETA 4N1ZF 3KRFA 4LLSA 4KVIA 3MAVA 3N6KF 5EAUA 4JYXA 4P0XA 2ONHA 3KRCA 5CG6A 3DYGA 4H5CF 4OGUA 1VG2A 2F92F 1YHKA 2AZKA 1HM7A 2H8OA 2PS8A 4LIXA 2OGDA 4DWGA 4E9UA 3V1VA 3WEFA 4XQTF 3N0GA 3ICZA 3N45F 3LEEA 2PS6A 2E8TA 4EA1A 3PYAA 3SAEA 4DEMF 3PH7A 1V4JA 3Q2ZA 5IL8A 3ZMCA 1V4IA 3RYWA 3G4FA 1N21A 3WEKA 5IK6A 1V4EA 5IK9A 3BNXA 3EFQA 5CG5A 3WE9A 3WCFA 3ACXA 4GP2A 3OYRA 5DHKA 3VJEA 3V1XA 4DXJA 2I19A 3S9VA 2ZCQA 5DJVF 4NFJF 3LDWA 1HXCA 3M02A 5IMNA 3WCJA 1YV5A 2E92A 2AZLA 4LFGA 3NF2A 3KRAB 2E8XA 3SDTA 2AELA 2OPMA 3EGTA 2QISA 3IBAA 5HN7A 5E8HA 1WL3A 3ID0A 1YHMA 5B03A 3KRFB 3P41A 3VJBA 5E8LA 1N22A 1YHLA 2Q58A 3LVSA 2F8CF 5HN9A 4PVXF 3SDUA 1YYTA 3KRCB 4H5EF 1JFAA 2OPNA 2Z50A 1WY0A 3WEIA 4KVYA 4Q23A 3VJ8A 3P8RA 5ILJA 3WCCA 3LJIA 2VF6A 4XQSF 2O1OA 5IMIA 5C05A 3NPKA 2DH4A 3LOMA 1PS1A 5JV1F 4L2XF 5B00A 2ZEVA 1V4KA 4LTVA 3TS7A 2AEKA 4N9UA 3LZ9A 2J5CA 3TFNA 4OKZA 1KIYA 2E8VA 5ERMA 3B7LA 4KQUA 1YYRA 4OMHA 3KRPA 5JUZF 3ICKA 5IM1A 3SDQA 1VG4A 3ICNA 3WJOA 5ILYA 5B0MA 3WCIA 5KSXF 3P8LA 1VG6A 2Z4XA 4OKMA 1UBWA 5H9DA 4LZCA 5AHUB 5B0IA 3P5PA 4GAXA 2Q80A 3N3DA 1VG7A 4LLTA 4LTZA 1DGPA 4EA0A 3KROA 3VJAA 3N1WF 5ILZA 5DGMF 5A0KA 3NPRA 2AZJA 2E91A 1UBYA 4KFAA 4UMJA 5AFXA 4NUAA 1WL1A 1WL2A 4JXYA 2E90A 5AYPA 5DGSF 2PS5A 3AQCB 3ACYA 3ICMA 3WCLA 3ACWA 4RXAA 4HD1A 5E8KA 4JVJF 5IN8A 4LUUA 3WCMA 4NFIF 1RQIA 5IKHA 3WEHA 3LGKA 5ER8A 2PS7A 2Q9YA 3ASXA 3AE0A 2Z7HA 3RBMA 4JXNA 2J1OA 4DHDA 3MZVA 4LFEA 3WJNA 3OACA 3ZCDA 4KQSA 4KPDA 3VJ9A 2F9KF 2PS4A 3G4DA 3N1VF 4MC8A 2Z4WA 4JZXA 5A0JA 1RQJA 4KK2A 5DIQF 3WCGA 4KWDA 5JA0F 1UBXA 5IKAA 4E1EA 5B0LA 1KIZA 2Z4VA 2E8UA 1ZW5A 2E8WA 1HXAA 5JV0F 3PDEA 5JV2F 1YJ4A 2J1PA 1JFGA 5IK0A 4P0VA 3LK5A 5EATA 4DWBA 5B02A 1YYSA 3EZ3A 3SDVA 4OMGA 3DYFA 3KROB 3WCEA 4KPJA 5A0IA 1HM4A 1YYUA 3W7FA 4F6XA 4RNQA 2ONGA 3WEJA 3WSBA 3M0GA 1N23A 3KRAA 5DW7A 1EZFA 3ZL6A 4LOBA 3RMGA 3N0FA 2F8ZF 3UCAA 3SDRA 4EA2A 4F62A 2Z52A 4XQRF 2ZY1A 3LGZB 3ADZA 5HNAA 4K10A 5B01A 3TC1A 5ERNA 3M00A 1V4HA 3N5JF 2ZCOA 4F6VA 3AQBB 5EASA 3NRIA 5DJPF 3CC9A 3N49F 3CKEA 3OABA 3IPIA 4LA6A 3S4JA 1UBVA 2E94A 4KUXA 3VJCA 3WCAA 1YYQA 3PKOA 4NG6A 3VJDA 3OACB 3KBKA 2P1CA 4MC3A 2Z4YA 2Z4ZA 3LLWA 4RXDA 4GP1A 1FPSA 4LPHF 4LZ3A 3N5HF 2E4OA 4NFKF 5EROA 1VG3A 4NKEA 4RXCA 5DZ2A 3LMDA 1N24A 2F7MF 4JZBA 1N1ZA 5ILIA 3N3LF 4QPFA 2RAHA 2OA6A 4WK5A 4DI5A 3N46F 4LFVF 5IL3A 3APZA 3PYBA 3WEGA 3V66A 4RYPA 3P5RA 3QKCA 3WC9A 3QQVA 4H5DF 5ILDA 2E93A 4LZ0A 4GA3A 4KVDA 3Q30A 4FJQA 1HXGA 2ZCSA 2FORA 4MC0A 3LG5A 3TFVA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3KB9 A;  5ILK A;  5DHI A;  3M9U A;  5I1U A;  3WCB A;  3Q2Q A;  3KRP B;  4ZQ8 A;  1DI1 A;  4LA5 A;  3ZOU A;  5DJR F;  4P0W A;  1WL0 A;  2Z7I A;  4LXW A;  4KVW A;  1N20 A;  3LSN A;  1WMW A;  4FP4 A;  2EWG A;  3CP6 A;  2Q9Z A;  3WCH A;  3AQ0 A;  4NKF A;  1N1B A;  5HN8 A;  2FTZ A;  2ZCR A;  4QXS F;  3RYE A;  3DYH A;  2F94 F;  1RTR A;  2E95 A;  3WCD A;  5B0J A;  2F89 F;  3OAB B;  3WJK A;  4E9Z A;  5IMP A;  4DZW A;  2Z78 A;  1HX9 A;  3Q1O A;  4RXE A;  5IVG A;  5B0K A;  1WKZ A;  1YQ7 A;  5DGN F;  3WSA A;  3BNY A;  4KQ5 A;  4PVY F;  3M01 A;  5AEL A;  3TFP A;  3ZMB A;  4KKM A;  4LPG F;  2ZEU A;  5ILH A;  2AET A;  4N1Z F;  3KRF A;  4LLS A;  4KVI A;  3MAV A;  3N6K F;  5EAU A;  4JYX A;  4P0X A;  2ONH A;  3KRC A;  5CG6 A;  3DYG A;  4H5C F;  4OGU A;  1VG2 A;  2F92 F;  1YHK A;  2AZK A;  1HM7 A;  2H8O A;  2PS8 A;  4LIX A;  2OGD A;  4DWG A;  4E9U A;  3V1V A;  3WEF A;  4XQT F;  3N0G A;  3ICZ A;  3N45 F;  3LEE A;  2PS6 A;  2E8T A;  4EA1 A;  3PYA A;  3SAE A;  4DEM F;  3PH7 A;  1V4J A;  3Q2Z A;  5IL8 A;  3ZMC A;  1V4I A;  3RYW A;  3G4F A;  1N21 A;  3WEK A;  5IK6 A;  1V4E A;  5IK9 A;  3BNX A;  3EFQ A;  5CG5 A;  3WE9 A;  3WCF A;  3ACX A;  4GP2 A;  3OYR A;  5DHK A;  3VJE A;  3V1X A;  4DXJ A;  2I19 A;  3S9V A;  2ZCQ A;  5DJV F;  4NFJ F;  3LDW A;  1HXC A;  3M02 A;  5IMN A;  3WCJ A;  1YV5 A;  2E92 A;  2AZL A;  4LFG A;  3NF2 A;  3KRA B;  2E8X A;  3SDT A;  2AEL A;  2OPM A;  3EGT A;  2QIS A;  3IBA A;  5HN7 A;  5E8H A;  1WL3 A;  3ID0 A;  1YHM A;  5B03 A;  3KRF B;  3P41 A;  3VJB A;  5E8L A;  1N22 A;  1YHL A;  2Q58 A;  3LVS A;  2F8C F;  5HN9 A;  4PVX F;  3SDU A;  1YYT A;  3KRC B;  4H5E F;  1JFA A;  2OPN A;  2Z50 A;  1WY0 A;  3WEI A;  4KVY A;  4Q23 A;  3VJ8 A;  3P8R A;  5ILJ A;  3WCC A;  3LJI A;  2VF6 A;  4XQS F;  2O1O A;  5IMI A;  5C05 A;  3NPK A;  2DH4 A;  3LOM A;  1PS1 A;  5JV1 F;  4L2X F;  5B00 A;  2ZEV A;  1V4K A;  4LTV A;  3TS7 A;  2AEK A;  4N9U A;  3LZ9 A;  2J5C A;  3TFN A;  4OKZ A;  1KIY A;  2E8V A;  5ERM A;  3B7L A;  4KQU A;  1YYR A;  4OMH A;  3KRP A;  5JUZ F;  3ICK A;  5IM1 A;  3SDQ A;  1VG4 A;  3ICN A;  3WJO A;  5ILY A;  5B0M A;  3WCI A;  5KSX F;  3P8L A;  1VG6 A;  2Z4X A;  4OKM A;  1UBW A;  5H9D A;  4LZC A;  5AHU B;  5B0I A;  3P5P A;  4GAX A;  2Q80 A;  3N3D A;  1VG7 A;  4LLT A;  4LTZ A;  1DGP A;  4EA0 A;  3KRO A;  3VJA A;  3N1W F;  5ILZ A;  5DGM F;  5A0K A;  3NPR A;  2AZJ A;  2E91 A;  1UBY A;  4KFA A;  4UMJ A;  5AFX A;  4NUA A;  1WL1 A;  1WL2 A;  4JXY A;  2E90 A;  5AYP A;  5DGS F;  2PS5 A;  3AQC B;  3ACY A;  3ICM A;  3WCL A;  3ACW A;  4RXA A;  4HD1 A;  5E8K A;  4JVJ F;  5IN8 A;  4LUU A;  3WCM A;  4NFI F;  1RQI A;  5IKH A;  3WEH A;  3LGK A;  5ER8 A;  2PS7 A;  2Q9Y A;  3ASX A;  3AE0 A;  2Z7H A;  3RBM A;  4JXN A;  2J1O A;  4DHD A;  3MZV A;  4LFE A;  3WJN A;  3OAC A;  3ZCD A;  4KQS A;  4KPD A;  3VJ9 A;  2F9K F;  2PS4 A;  3G4D A;  3N1V F;  4MC8 A;  2Z4W A;  4JZX A;  5A0J A;  1RQJ A;  4KK2 A;  5DIQ F;  3WCG A;  4KWD A;  5JA0 F;  1UBX A;  5IKA A;  4E1E A;  5B0L A;  1KIZ A;  2Z4V A;  2E8U A;  1ZW5 A;  2E8W A;  1HXA A;  5JV0 F;  3PDE A;  5JV2 F;  1YJ4 A;  2J1P A;  1JFG A;  5IK0 A;  4P0V A;  3LK5 A;  5EAT A;  4DWB A;  5B02 A;  1YYS A;  3EZ3 A;  3SDV A;  4OMG A;  3DYF A;  3KRO B;  3WCE A;  4KPJ A;  5A0I A;  1HM4 A;  1YYU A;  3W7F A;  4F6X A;  4RNQ A;  2ONG A;  3WEJ A;  3WSB A;  3M0G A;  1N23 A;  3KRA A;  5DW7 A;  1EZF A;  3ZL6 A;  4LOB A;  3RMG A;  3N0F A;  2F8Z F;  3UCA A;  3SDR A;  4EA2 A;  4F62 A;  2Z52 A;  4XQR F;  2ZY1 A;  3LGZ B;  3ADZ A;  5HNA A;  4K10 A;  5B01 A;  3TC1 A;  5ERN A;  3M00 A;  1V4H A;  3N5J F;  2ZCO A;  4F6V A;  3AQB B;  5EAS A;  3NRI A;  5DJP F;  3CC9 A;  3N49 F;  3CKE A;  3OAB A;  3IPI A;  4LA6 A;  3S4J A;  1UBV A;  2E94 A;  4KUX A;  3VJC A;  3WCA A;  1YYQ A;  3PKO A;  4NG6 A;  3VJD A;  3OAC B;  3KBK A;  2P1C A;  4MC3 A;  2Z4Y A;  2Z4Z A;  3LLW A;  4RXD A;  4GP1 A;  1FPS A;  4LPH F;  4LZ3 A;  3N5H F;  2E4O A;  4NFK F;  5ERO A;  1VG3 A;  4NKE A;  4RXC A;  5DZ2 A;  3LMD A;  1N24 A;  2F7M F;  4JZB A;  1N1Z A;  5ILI A;  3N3L F;  4QPF A;  2RAH A;  2OA6 A;  4WK5 A;  4DI5 A;  3N46 F;  4LFV F;  5IL3 A;  3APZ A;  3PYB A;  3WEG A;  3V66 A;  4RYP A;  3P5R A;  3QKC A;  3WC9 A;  3QQV A;  4H5D F;  5ILD A;  2E93 A;  4LZ0 A;  4GA3 A;  4KVD A;  3Q30 A;  4FJQ A;  1HXG A;  2ZCS A;  2FOR A;  4MC0 A;  3LG5 A;  3TFV A; 
#chains in the Genus database with same CATH topology
 3KB9 A;  5ILK A;  5DHI A;  3M9U A;  5I1U A;  3WCB A;  3Q2Q A;  3KRP B;  4ZQ8 A;  1DI1 A;  4LA5 A;  3ZOU A;  5DJR F;  4P0W A;  1WL0 A;  2Z7I A;  4LXW A;  4KVW A;  1N20 A;  3LSN A;  1WMW A;  4FP4 A;  2EWG A;  3CP6 A;  2Q9Z A;  3WCH A;  3AQ0 A;  4NKF A;  1N1B A;  5HN8 A;  2FTZ A;  2ZCR A;  4QXS F;  3RYE A;  3DYH A;  2F94 F;  1RTR A;  2E95 A;  3WCD A;  5B0J A;  2F89 F;  3OAB B;  3WJK A;  4E9Z A;  5IMP A;  4DZW A;  2Z78 A;  1HX9 A;  3Q1O A;  4RXE A;  5IVG A;  5B0K A;  1WKZ A;  1YQ7 A;  5DGN F;  3WSA A;  3BNY A;  4KQ5 A;  4PVY F;  3M01 A;  5AEL A;  3TFP A;  3ZMB A;  4KKM A;  4LPG F;  2ZEU A;  5ILH A;  2AET A;  4N1Z F;  3KRF A;  4LLS A;  4KVI A;  3MAV A;  3N6K F;  5EAU A;  4JYX A;  4P0X A;  2ONH A;  3KRC A;  5CG6 A;  3DYG A;  4H5C F;  4OGU A;  1VG2 A;  2F92 F;  1YHK A;  2AZK A;  1HM7 A;  2H8O A;  2PS8 A;  4LIX A;  2OGD A;  4DWG A;  4E9U A;  3V1V A;  3WEF A;  4XQT F;  3N0G A;  3ICZ A;  3N45 F;  3LEE A;  2PS6 A;  2E8T A;  4EA1 A;  3PYA A;  3SAE A;  4DEM F;  3PH7 A;  1V4J A;  3Q2Z A;  5IL8 A;  3ZMC A;  1V4I A;  3RYW A;  3G4F A;  1N21 A;  3WEK A;  5IK6 A;  1V4E A;  5IK9 A;  3BNX A;  3EFQ A;  5CG5 A;  3WE9 A;  3WCF A;  3ACX A;  4GP2 A;  3OYR A;  5DHK A;  3VJE A;  3V1X A;  4DXJ A;  2I19 A;  3S9V A;  2ZCQ A;  5DJV F;  4NFJ F;  3LDW A;  1HXC A;  3M02 A;  5IMN A;  3WCJ A;  1YV5 A;  2E92 A;  2AZL A;  4LFG A;  3NF2 A;  3KRA B;  2E8X A;  3SDT A;  2AEL A;  2OPM A;  3EGT A;  2QIS A;  3IBA A;  5HN7 A;  5E8H A;  1WL3 A;  3ID0 A;  1YHM A;  5B03 A;  3KRF B;  3P41 A;  3VJB A;  5E8L A;  1N22 A;  1YHL A;  2Q58 A;  3LVS A;  2F8C F;  5HN9 A;  4PVX F;  3SDU A;  1YYT A;  3KRC B;  4H5E F;  1JFA A;  2OPN A;  2Z50 A;  1WY0 A;  3WEI A;  4KVY A;  4Q23 A;  3VJ8 A;  3P8R A;  5ILJ A;  3WCC A;  3LJI A;  2VF6 A;  4XQS F;  2O1O A;  5IMI A;  5C05 A;  3NPK A;  2DH4 A;  3LOM A;  1PS1 A;  5JV1 F;  4L2X F;  5B00 A;  2ZEV A;  1V4K A;  4LTV A;  3TS7 A;  2AEK A;  4N9U A;  3LZ9 A;  2J5C A;  3TFN A;  4OKZ A;  1KIY A;  2E8V A;  5ERM A;  3B7L A;  4KQU A;  1YYR A;  4OMH A;  3KRP A;  5JUZ F;  3ICK A;  5IM1 A;  3SDQ A;  1VG4 A;  3ICN A;  3WJO A;  5ILY A;  5B0M A;  3WCI A;  5KSX F;  3P8L A;  1VG6 A;  2Z4X A;  4OKM A;  1UBW A;  5H9D A;  4LZC A;  5AHU B;  5B0I A;  3P5P A;  4GAX A;  2Q80 A;  3N3D A;  1VG7 A;  4LLT A;  4LTZ A;  1DGP A;  4EA0 A;  3KRO A;  3VJA A;  3N1W F;  5ILZ A;  5DGM F;  5A0K A;  3NPR A;  2AZJ A;  2E91 A;  1UBY A;  4KFA A;  4UMJ A;  5AFX A;  4NUA A;  1WL1 A;  1WL2 A;  4JXY A;  2E90 A;  5AYP A;  5DGS F;  2PS5 A;  3AQC B;  3ACY A;  3ICM A;  3WCL A;  3ACW A;  4RXA A;  4HD1 A;  5E8K A;  4JVJ F;  5IN8 A;  4LUU A;  3WCM A;  4NFI F;  1RQI A;  5IKH A;  3WEH A;  3LGK A;  5ER8 A;  2PS7 A;  2Q9Y A;  3ASX A;  3AE0 A;  2Z7H A;  3RBM A;  4JXN A;  2J1O A;  4DHD A;  3MZV A;  4LFE A;  3WJN A;  3OAC A;  3ZCD A;  4KQS A;  4KPD A;  3VJ9 A;  2F9K F;  2PS4 A;  3G4D A;  3N1V F;  4MC8 A;  2Z4W A;  4JZX A;  5A0J A;  1RQJ A;  4KK2 A;  5DIQ F;  3WCG A;  4KWD A;  5JA0 F;  1UBX A;  5IKA A;  4E1E A;  5B0L A;  1KIZ A;  2Z4V A;  2E8U A;  1ZW5 A;  2E8W A;  1HXA A;  5JV0 F;  3PDE A;  5JV2 F;  1YJ4 A;  2J1P A;  1JFG A;  5IK0 A;  4P0V A;  3LK5 A;  5EAT A;  4DWB A;  5B02 A;  1YYS A;  3EZ3 A;  3SDV A;  4OMG A;  3DYF A;  3KRO B;  3WCE A;  4KPJ A;  5A0I A;  1HM4 A;  1YYU A;  3W7F A;  4F6X A;  4RNQ A;  2ONG A;  3WEJ A;  3WSB A;  3M0G A;  1N23 A;  3KRA A;  5DW7 A;  1EZF A;  3ZL6 A;  4LOB A;  3RMG A;  3N0F A;  2F8Z F;  3UCA A;  3SDR A;  4EA2 A;  4F62 A;  2Z52 A;  4XQR F;  2ZY1 A;  3LGZ B;  3ADZ A;  5HNA A;  4K10 A;  5B01 A;  3TC1 A;  5ERN A;  3M00 A;  1V4H A;  3N5J F;  2ZCO A;  4F6V A;  3AQB B;  5EAS A;  3NRI A;  5DJP F;  3CC9 A;  3N49 F;  3CKE A;  3OAB A;  3IPI A;  4LA6 A;  3S4J A;  1UBV A;  2E94 A;  4KUX A;  3VJC A;  3WCA A;  1YYQ A;  3PKO A;  4NG6 A;  3VJD A;  3OAC B;  3KBK A;  2P1C A;  4MC3 A;  2Z4Y A;  2Z4Z A;  3LLW A;  4RXD A;  4GP1 A;  1FPS A;  4LPH F;  4LZ3 A;  3N5H F;  2E4O A;  4NFK F;  5ERO A;  1VG3 A;  4NKE A;  4RXC A;  5DZ2 A;  3LMD A;  1N24 A;  2F7M F;  4JZB A;  1N1Z A;  5ILI A;  3N3L F;  4QPF A;  2RAH A;  2OA6 A;  4WK5 A;  4DI5 A;  3N46 F;  4LFV F;  5IL3 A;  3APZ A;  3PYB A;  3WEG A;  3V66 A;  4RYP A;  3P5R A;  3QKC A;  3WC9 A;  3QQV A;  4H5D F;  5ILD A;  2E93 A;  4LZ0 A;  4GA3 A;  4KVD A;  3Q30 A;  4FJQ A;  1HXG A;  2ZCS A;  2FOR A;  4MC0 A;  3LG5 A;  3TFV A; 
#chains in the Genus database with same CATH homology
 3KB9 A;  5ILK A;  5DHI A;  3M9U A;  5I1U A;  3WCB A;  3Q2Q A;  3KRP B;  4ZQ8 A;  1DI1 A;  4LA5 A;  3ZOU A;  5DJR F;  4P0W A;  1WL0 A;  2Z7I A;  4LXW A;  4KVW A;  1N20 A;  3LSN A;  1WMW A;  4FP4 A;  2EWG A;  3CP6 A;  2Q9Z A;  3WCH A;  3AQ0 A;  4NKF A;  1N1B A;  5HN8 A;  2FTZ A;  2ZCR A;  4QXS F;  3RYE A;  3DYH A;  2F94 F;  1RTR A;  2E95 A;  3WCD A;  5B0J A;  2F89 F;  3OAB B;  3WJK A;  4E9Z A;  5IMP A;  4DZW A;  2Z78 A;  1HX9 A;  3Q1O A;  4RXE A;  5IVG A;  5B0K A;  1WKZ A;  1YQ7 A;  5DGN F;  3WSA A;  3BNY A;  4KQ5 A;  4PVY F;  3M01 A;  5AEL A;  3TFP A;  3ZMB A;  4KKM A;  4LPG F;  2ZEU A;  5ILH A;  2AET A;  4N1Z F;  3KRF A;  4LLS A;  4KVI A;  3MAV A;  3N6K F;  5EAU A;  4JYX A;  4P0X A;  2ONH A;  3KRC A;  5CG6 A;  3DYG A;  4H5C F;  4OGU A;  1VG2 A;  2F92 F;  1YHK A;  2AZK A;  1HM7 A;  2H8O A;  2PS8 A;  4LIX A;  2OGD A;  4DWG A;  4E9U A;  3V1V A;  3WEF A;  4XQT F;  3N0G A;  3ICZ A;  3N45 F;  3LEE A;  2PS6 A;  2E8T A;  4EA1 A;  3PYA A;  3SAE A;  4DEM F;  3PH7 A;  1V4J A;  3Q2Z A;  5IL8 A;  3ZMC A;  1V4I A;  3RYW A;  3G4F A;  1N21 A;  3WEK A;  5IK6 A;  1V4E A;  5IK9 A;  3BNX A;  3EFQ A;  5CG5 A;  3WE9 A;  3WCF A;  3ACX A;  4GP2 A;  3OYR A;  5DHK A;  3VJE A;  3V1X A;  4DXJ A;  2I19 A;  3S9V A;  2ZCQ A;  5DJV F;  4NFJ F;  3LDW A;  1HXC A;  3M02 A;  5IMN A;  3WCJ A;  1YV5 A;  2E92 A;  2AZL A;  4LFG A;  3NF2 A;  3KRA B;  2E8X A;  3SDT A;  2AEL A;  2OPM A;  3EGT A;  2QIS A;  3IBA A;  5HN7 A;  5E8H A;  1WL3 A;  3ID0 A;  1YHM A;  5B03 A;  3KRF B;  3P41 A;  3VJB A;  5E8L A;  1N22 A;  1YHL A;  2Q58 A;  3LVS A;  2F8C F;  5HN9 A;  4PVX F;  3SDU A;  1YYT A;  3KRC B;  4H5E F;  1JFA A;  2OPN A;  2Z50 A;  1WY0 A;  3WEI A;  4KVY A;  4Q23 A;  3VJ8 A;  3P8R A;  5ILJ A;  3WCC A;  3LJI A;  2VF6 A;  4XQS F;  2O1O A;  5IMI A;  5C05 A;  3NPK A;  2DH4 A;  3LOM A;  1PS1 A;  5JV1 F;  4L2X F;  5B00 A;  2ZEV A;  1V4K A;  4LTV A;  3TS7 A;  2AEK A;  4N9U A;  3LZ9 A;  2J5C A;  3TFN A;  4OKZ A;  1KIY A;  2E8V A;  5ERM A;  3B7L A;  4KQU A;  1YYR A;  4OMH A;  3KRP A;  5JUZ F;  3ICK A;  5IM1 A;  3SDQ A;  1VG4 A;  3ICN A;  3WJO A;  5ILY A;  5B0M A;  3WCI A;  5KSX F;  3P8L A;  1VG6 A;  2Z4X A;  4OKM A;  1UBW A;  5H9D A;  4LZC A;  5AHU B;  5B0I A;  3P5P A;  4GAX A;  2Q80 A;  3N3D A;  1VG7 A;  4LLT A;  4LTZ A;  1DGP A;  4EA0 A;  3KRO A;  3VJA A;  3N1W F;  5ILZ A;  5DGM F;  5A0K A;  3NPR A;  2AZJ A;  2E91 A;  1UBY A;  4KFA A;  4UMJ A;  5AFX A;  4NUA A;  1WL1 A;  1WL2 A;  4JXY A;  2E90 A;  5AYP A;  5DGS F;  2PS5 A;  3AQC B;  3ACY A;  3ICM A;  3WCL A;  3ACW A;  4RXA A;  4HD1 A;  5E8K A;  4JVJ F;  5IN8 A;  4LUU A;  3WCM A;  4NFI F;  1RQI A;  5IKH A;  3WEH A;  3LGK A;  5ER8 A;  2PS7 A;  2Q9Y A;  3ASX A;  3AE0 A;  2Z7H A;  3RBM A;  4JXN A;  2J1O A;  4DHD A;  3MZV A;  4LFE A;  3WJN A;  3OAC A;  3ZCD A;  4KQS A;  4KPD A;  3VJ9 A;  2F9K F;  2PS4 A;  3G4D A;  3N1V F;  4MC8 A;  2Z4W A;  4JZX A;  5A0J A;  1RQJ A;  4KK2 A;  5DIQ F;  3WCG A;  4KWD A;  5JA0 F;  1UBX A;  5IKA A;  4E1E A;  5B0L A;  1KIZ A;  2Z4V A;  2E8U A;  1ZW5 A;  2E8W A;  1HXA A;  5JV0 F;  3PDE A;  5JV2 F;  1YJ4 A;  2J1P A;  1JFG A;  5IK0 A;  4P0V A;  3LK5 A;  5EAT A;  4DWB A;  5B02 A;  1YYS A;  3EZ3 A;  3SDV A;  4OMG A;  3DYF A;  3KRO B;  3WCE A;  4KPJ A;  5A0I A;  1HM4 A;  1YYU A;  3W7F A;  4F6X A;  4RNQ A;  2ONG A;  3WEJ A;  3WSB A;  3M0G A;  1N23 A;  3KRA A;  5DW7 A;  1EZF A;  3ZL6 A;  4LOB A;  3RMG A;  3N0F A;  2F8Z F;  3UCA A;  3SDR A;  4EA2 A;  4F62 A;  2Z52 A;  4XQR F;  2ZY1 A;  3LGZ B;  3ADZ A;  5HNA A;  4K10 A;  5B01 A;  3TC1 A;  5ERN A;  3M00 A;  1V4H A;  3N5J F;  2ZCO A;  4F6V A;  3AQB B;  5EAS A;  3NRI A;  5DJP F;  3CC9 A;  3N49 F;  3CKE A;  3OAB A;  3IPI A;  4LA6 A;  3S4J A;  1UBV A;  2E94 A;  4KUX A;  3VJC A;  3WCA A;  1YYQ A;  3PKO A;  4NG6 A;  3VJD A;  3OAC B;  3KBK A;  2P1C A;  4MC3 A;  2Z4Y A;  2Z4Z A;  3LLW A;  4RXD A;  4GP1 A;  1FPS A;  4LPH F;  4LZ3 A;  3N5H F;  2E4O A;  4NFK F;  5ERO A;  1VG3 A;  4NKE A;  4RXC A;  5DZ2 A;  3LMD A;  1N24 A;  2F7M F;  4JZB A;  1N1Z A;  5ILI A;  3N3L F;  4QPF A;  2RAH A;  2OA6 A;  4WK5 A;  4DI5 A;  3N46 F;  4LFV F;  5IL3 A;  3APZ A;  3PYB A;  3WEG A;  3V66 A;  4RYP A;  3P5R A;  3QKC A;  3WC9 A;  3QQV A;  4H5D F;  5ILD A;  2E93 A;  4LZ0 A;  4GA3 A;  4KVD A;  3Q30 A;  4FJQ A;  1HXG A;  2ZCS A;  2FOR A;  4MC0 A;  3LG5 A;  3TFV A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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