4P0VA

Crystal structure of human farnesyl diphosphoate synthase in complex with zoledronate and taxodione
Total Genus 137
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
137
sequence length
346
structure length
346
Chain Sequence
DVYAQEKQDFVQHFSQIVRVLTEDEMGHPEIGDAIARLKEVLEYNAIGGKYNRGLTVVVAFRELVEPRKQDADSLQRAWTVGWCVELLQAFFLVADDIMDSSLTRRGQICWYQKPGVGLDAINDANLLEACIYRLLKLYCREQPYYLNLIELFLQSSYQTEIGQTLDLLTAPQGNVDLVRFTEKRYKSIVKYKTAFYSFYLPIAAAMYMAGIDGEKEHANAKKILLEMGEFFQIQDDYLDLFGDPSVTGKIGTDIQDNKCSWLVVQCLQRATPEQYQILKENYGQKEAEKVARVKALYEELDLPAVFLQYEEDSYSHIMALIEQYAAPLPPAVFLGLARKIYKRRK
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Transferase/transferase inhibitor
source organism Homo sapiens
publication title Taxodione and arenarone inhibit farnesyl diphosphate synthase by binding to the isopentenyl diphosphate site.
pubmed doi rcsb
molecule keywords Farnesyl pyrophosphate synthase
total genus 137
structure length 346
sequence length 346
ec nomenclature ec 2.5.1.1: Dimethylallyltranstransferase.
pdb deposition date 2014-02-23

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00348 polyprenyl_synt Polyprenyl synthetase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.600.10 Mainly Alpha Orthogonal Bundle Farnesyl Diphosphate Synthase Farnesyl Diphosphate Synthase 4p0vA00
4OMHA 4RXEA 3WEFA 2E8XA 3WEHA 4JXNA 3CKEA 1N21A 2F7MF 4OKMA 3WCBA 3PYBA 1RTRA 4MC0A 3KROB 3WCHA 4GAXA 3RYEA 4PVXF 5B01A 3V1XA 5H9DA 5KSXF 4GP2A 5IMIA 1V4HA 3Q30A 5HN9A 1JFGA 3TFVA 3VJCA 2E94A 5JV2F 5E8KA 3ADZA 2H8OA 1N24A 4OKZA 3B7LA 2AEKA 3RMGA 3WSBA 3NPRA 4DHDA 4KUXA 4KWDA 3IBAA 4H5EF 3SDRA 2PS4A 3G4DA 4P0XA 4LTZA 1VG4A 3Q1OA 4LA5A 4LPHF 4LLSA 1UBXA 3ACWA 5IK9A 2PS6A 4E9ZA 3KRFA 2PS8A 1WL1A 4LFEA 2J1OA 3ICNA 4F62A 3APZA 2ZCQA 5CG6A 1VG2A 5HN7A 5B0IA 3SDVA 1HM4A 2F94F 3ZMBA 2OPNA 3DYGA 5E8LA 4LZCA 1HXGA 4FP4A 2F89F 5DW7A 4OMGA 1YV5A 2J5CA 2E92A 4KQUA 5B0JA 5ILHA 2E8TA 1YYQA 1JFAA 5AHUB 4JZXA 1DGPA 5IMPA 4E9UA 5DJPF 5AFXA 3TC1A 4UMJA 4KK2A 2ONHA 2Z4WA 5I1UA 5B0MA 5ERNA 2QISA 2E8UA 3LSNA 2F92F 4WK5A 2FORA 3OACA 3BNYA 1YQ7A 5B0LA 3LDWA 4HD1A 1DI1A 4GA3A 3N49F 3G4FA 1WKZA 3N45F 1WL3A 3P5PA 3KB9A 4KVIA 3UCAA 1ZW5A 1UBWA 2ZY1A 3KRAB 2O1OA 2Q9ZA 3LG5A 5EASA 4F6VA 4H5DF 1YHKA 3PH7A 2AZLA 3N6KF 3QQVA 3CC9A 4LPGF 3KBKA 4RXDA 5AELA 3OABA 3KRCA 3SDQA 3S9VA 2Z4ZA 3MAVA 1HXCA 1V4IA 4RNQA 4MC8A 4P0VA 5ILIA 3M0GA 4LFVF 4JVJF 1N22A 4NG6A 5EATA 3OYRA 3WCGA 3VJ9A 4LUUA 4KQ5A 2PS5A 3N1VF 2E90A 4F6XA 2E91A 1YYUA 4JXYA 3WCLA 4P0WA 5JA0F 2E93A 1HX9A 4GP1A 1PS1A 2E8WA 4KFAA 1HM7A 4LZ3A 5IM1A 5HNAA 1VG3A 4QXSF 3N5HF 2AELA 3ZOUA 3TFNA 2ZEVA 3QKCA 2E4OA 3VJAA 1WL2A 4NKFA 3WCFA 3TS7A 4DZWA 3WCIA 3DYFA 4Q23A 3KRPA 5DGMF 3WCJA 3WCAA 5IK6A 3CP6A 3RYWA 5B02A 1N1BA 3N1WF 3WEGA 3WEKA 1YJ4A 4XQSF 4EA2A 3KROA 5DHKA 3N0GA 3P8LA 5ILKA 1EZFA 2RAHA 2OA6A 5IK0A 3Q2ZA 5CG5A 3N3DA 3LLWA 3WCEA 5ILDA 5IN8A 4RXCA 1N23A 2AETA 2P1CA 5A0JA 1YHLA 2Z7IA 5IMNA 5ILZA 2I19A 3WJNA 4EA1A 2Z4YA 3ACXA 2Z50A 3LJIA 3NF2A 4KVYA 4LOBA 1YYTA 2F9KF 2AZJA 4N9UA 3VJDA 4DWGA 5ILYA 5IKHA 5JUZF 3ACYA 3IPIA 2Q58A 3AQCB 3EGTA 4LA6A 5DJRF 3WJOA 4DI5A 3SDTA 3PDEA 5DZ2A 2OPMA 1WY0A 3WCMA 1FPSA 3WCCA 4FJQA 3V1VA 3M01A 3WJKA 2ZEUA 3WSAA 3LEEA 3ZL6A 3ICKA 1YYRA 2F8CF 3P41A 4NFKF 5JV0F 3BNXA 3V66A 3ASXA 5JV1F 3VJBA 3LGZB 3Q2QA 2VF6A 3S4JA 4H5CF 5DGNF 4KVDA 4LTVA 4L2XF 3LZ9A 3KRFB 5AYPA 4E1EA 3LMDA 4NKEA 2AZKA 4LZ0A 4PVYF 3LK5A 4OGUA 5DHIA 5IL8A 3N3LF 4NFJF 3SDUA 4DWBA 1WMWA 2Z52A 3VJ8A 5IL3A 2ZCOA 4K10A 4KKMA 1VG6A 4XQRF 2E95A 2Z4XA 3AQ0A 2EWGA 5A0KA 5ER8A 1V4JA 3M02A 3ID0A 3N5JF 3LVSA 5C05A 3EFQA 3P5RA 2Z7HA 3WCDA 1N20A 2Q80A 3LOMA 3LGKA 1N1ZA 3KRAA 3WEJA 5IKAA 2ZCSA 3M9UA 5EROA 5IVGA 4KPDA 4LIXA 3OACB 1UBVA 3P8RA 4ZQ8A 3MZVA 1VG7A 3ZMCA 2ZCRA 1HXAA 4KPJA 5DJVF 5B03A 1V4KA 4KVWA 3RBMA 2Z78A 5EAUA 4NFIF 1YHMA 5A0IA 2Q9YA 5DIQF 4DXJA 2FTZA 2OGDA 4N1ZF 4JYXA 4RXAA 4EA0A 4LFGA 3ICZA 5ILJA 5B0KA 1WL0A 2E8VA 3ICMA 4NUAA 3ZCDA 1YYSA 5E8HA 3SAEA 3NRIA 2J1PA 1RQIA 3OABB 4QPFA 4XQTF 3KRCB 3DYHA 2ONGA 5B00A 5ERMA 2DH4A 5HN8A 4DEMF 1KIYA 3M00A 1KIZA 3WE9A 3W7FA 1V4EA 4RYPA 4JZBA 4KQSA 3WC9A 3NPKA 1UBYA 4LXWA 1RQJA 2PS7A 2Z4VA 3TFPA 3AE0A 3VJEA 2F8ZF 3AQBB 4MC3A 3EZ3A 3PYAA 3WEIA 4LLTA 3PKOA 5DGSF 3N46F 3N0FA 3KRPB
chains in the Genus database with same CATH superfamily
4OMHA 4RXEA 3WEFA 2E8XA 3WEHA 4JXNA 3CKEA 1N21A 2F7MF 4OKMA 3WCBA 3PYBA 1RTRA 4MC0A 3KROB 3WCHA 4GAXA 3RYEA 4PVXF 5B01A 3V1XA 5H9DA 5KSXF 4GP2A 5IMIA 1V4HA 3Q30A 5HN9A 1JFGA 3TFVA 3VJCA 2E94A 5JV2F 5E8KA 3ADZA 2H8OA 1N24A 4OKZA 3B7LA 2AEKA 3RMGA 3WSBA 3NPRA 4DHDA 4KUXA 4KWDA 3IBAA 4H5EF 3SDRA 2PS4A 3G4DA 4P0XA 4LTZA 1VG4A 3Q1OA 4LA5A 4LPHF 4LLSA 1UBXA 3ACWA 5IK9A 2PS6A 4E9ZA 3KRFA 2PS8A 1WL1A 4LFEA 2J1OA 3ICNA 4F62A 3APZA 2ZCQA 5CG6A 1VG2A 5HN7A 5B0IA 3SDVA 1HM4A 2F94F 3ZMBA 2OPNA 3DYGA 5E8LA 4LZCA 1HXGA 4FP4A 2F89F 5DW7A 4OMGA 1YV5A 2J5CA 2E92A 4KQUA 5B0JA 5ILHA 2E8TA 1YYQA 1JFAA 5AHUB 4JZXA 1DGPA 5IMPA 4E9UA 5DJPF 5AFXA 3TC1A 4UMJA 4KK2A 2ONHA 2Z4WA 5I1UA 5B0MA 5ERNA 2QISA 2E8UA 3LSNA 2F92F 4WK5A 2FORA 3OACA 3BNYA 1YQ7A 5B0LA 3LDWA 4HD1A 1DI1A 4GA3A 3N49F 3G4FA 1WKZA 3N45F 1WL3A 3P5PA 3KB9A 4KVIA 3UCAA 1ZW5A 1UBWA 2ZY1A 3KRAB 2O1OA 2Q9ZA 3LG5A 5EASA 4F6VA 4H5DF 1YHKA 3PH7A 2AZLA 3N6KF 3QQVA 3CC9A 4LPGF 3KBKA 4RXDA 5AELA 3OABA 3KRCA 3SDQA 3S9VA 2Z4ZA 3MAVA 1HXCA 1V4IA 4RNQA 4MC8A 4P0VA 5ILIA 3M0GA 4LFVF 4JVJF 1N22A 4NG6A 5EATA 3OYRA 3WCGA 3VJ9A 4LUUA 4KQ5A 2PS5A 3N1VF 2E90A 4F6XA 2E91A 1YYUA 4JXYA 3WCLA 4P0WA 5JA0F 2E93A 1HX9A 4GP1A 1PS1A 2E8WA 4KFAA 1HM7A 4LZ3A 5IM1A 5HNAA 1VG3A 4QXSF 3N5HF 2AELA 3ZOUA 3TFNA 2ZEVA 3QKCA 2E4OA 3VJAA 1WL2A 4NKFA 3WCFA 3TS7A 4DZWA 3WCIA 3DYFA 4Q23A 3KRPA 5DGMF 3WCJA 3WCAA 5IK6A 3CP6A 3RYWA 5B02A 1N1BA 3N1WF 3WEGA 3WEKA 1YJ4A 4XQSF 4EA2A 3KROA 5DHKA 3N0GA 3P8LA 5ILKA 1EZFA 2RAHA 2OA6A 5IK0A 3Q2ZA 5CG5A 3N3DA 3LLWA 3WCEA 5ILDA 5IN8A 4RXCA 1N23A 2AETA 2P1CA 5A0JA 1YHLA 2Z7IA 5IMNA 5ILZA 2I19A 3WJNA 4EA1A 2Z4YA 3ACXA 2Z50A 3LJIA 3NF2A 4KVYA 4LOBA 1YYTA 2F9KF 2AZJA 4N9UA 3VJDA 4DWGA 5ILYA 5IKHA 5JUZF 3ACYA 3IPIA 2Q58A 3AQCB 3EGTA 4LA6A 5DJRF 3WJOA 4DI5A 3SDTA 3PDEA 5DZ2A 2OPMA 1WY0A 3WCMA 1FPSA 3WCCA 4FJQA 3V1VA 3M01A 3WJKA 2ZEUA 3WSAA 3LEEA 3ZL6A 3ICKA 1YYRA 2F8CF 3P41A 4NFKF 5JV0F 3BNXA 3V66A 3ASXA 5JV1F 3VJBA 3LGZB 3Q2QA 2VF6A 3S4JA 4H5CF 5DGNF 4KVDA 4LTVA 4L2XF 3LZ9A 3KRFB 5AYPA 4E1EA 3LMDA 4NKEA 2AZKA 4LZ0A 4PVYF 3LK5A 4OGUA 5DHIA 5IL8A 3N3LF 4NFJF 3SDUA 4DWBA 1WMWA 2Z52A 3VJ8A 5IL3A 2ZCOA 4K10A 4KKMA 1VG6A 4XQRF 2E95A 2Z4XA 3AQ0A 2EWGA 5A0KA 5ER8A 1V4JA 3M02A 3ID0A 3N5JF 3LVSA 5C05A 3EFQA 3P5RA 2Z7HA 3WCDA 1N20A 2Q80A 3LOMA 3LGKA 1N1ZA 3KRAA 3WEJA 5IKAA 2ZCSA 3M9UA 5EROA 5IVGA 4KPDA 4LIXA 3OACB 1UBVA 3P8RA 4ZQ8A 3MZVA 1VG7A 3ZMCA 2ZCRA 1HXAA 4KPJA 5DJVF 5B03A 1V4KA 4KVWA 3RBMA 2Z78A 5EAUA 4NFIF 1YHMA 5A0IA 2Q9YA 5DIQF 4DXJA 2FTZA 2OGDA 4N1ZF 4JYXA 4RXAA 4EA0A 4LFGA 3ICZA 5ILJA 5B0KA 1WL0A 2E8VA 3ICMA 4NUAA 3ZCDA 1YYSA 5E8HA 3SAEA 3NRIA 2J1PA 1RQIA 3OABB 4QPFA 4XQTF 3KRCB 3DYHA 2ONGA 5B00A 5ERMA 2DH4A 5HN8A 4DEMF 1KIYA 3M00A 1KIZA 3WE9A 3W7FA 1V4EA 4RYPA 4JZBA 4KQSA 3WC9A 3NPKA 1UBYA 4LXWA 1RQJA 2PS7A 2Z4VA 3TFPA 3AE0A 3VJEA 2F8ZF 3AQBB 4MC3A 3EZ3A 3PYAA 3WEIA 4LLTA 3PKOA 5DGSF 3N46F 3N0FA 3KRPB
chains in the Genus database with same CATH topology
4OMHA 4RXEA 3WEFA 2E8XA 3WEHA 4JXNA 3CKEA 1N21A 2F7MF 4OKMA 3WCBA 3PYBA 1RTRA 4MC0A 3KROB 3WCHA 4GAXA 3RYEA 4PVXF 5B01A 3V1XA 5H9DA 5KSXF 4GP2A 5IMIA 1V4HA 3Q30A 5HN9A 1JFGA 3TFVA 3VJCA 2E94A 5JV2F 5E8KA 3ADZA 2H8OA 1N24A 4OKZA 3B7LA 2AEKA 3RMGA 3WSBA 3NPRA 4DHDA 4KUXA 4KWDA 3IBAA 4H5EF 3SDRA 2PS4A 3G4DA 4P0XA 4LTZA 1VG4A 3Q1OA 4LA5A 4LPHF 4LLSA 1UBXA 3ACWA 5IK9A 2PS6A 4E9ZA 3KRFA 2PS8A 1WL1A 4LFEA 2J1OA 3ICNA 4F62A 3APZA 2ZCQA 5CG6A 1VG2A 5HN7A 5B0IA 3SDVA 1HM4A 2F94F 3ZMBA 2OPNA 3DYGA 5E8LA 4LZCA 1HXGA 4FP4A 2F89F 5DW7A 4OMGA 1YV5A 2J5CA 2E92A 4KQUA 5B0JA 5ILHA 2E8TA 1YYQA 1JFAA 5AHUB 4JZXA 1DGPA 5IMPA 4E9UA 5DJPF 5AFXA 3TC1A 4UMJA 4KK2A 2ONHA 2Z4WA 5I1UA 5B0MA 5ERNA 2QISA 2E8UA 3LSNA 2F92F 4WK5A 2FORA 3OACA 3BNYA 1YQ7A 5B0LA 3LDWA 4HD1A 1DI1A 4GA3A 3N49F 3G4FA 1WKZA 3N45F 1WL3A 3P5PA 3KB9A 4KVIA 3UCAA 1ZW5A 1UBWA 2ZY1A 3KRAB 2O1OA 2Q9ZA 3LG5A 5EASA 4F6VA 4H5DF 1YHKA 3PH7A 2AZLA 3N6KF 3QQVA 3CC9A 4LPGF 3KBKA 4RXDA 5AELA 3OABA 3KRCA 3SDQA 3S9VA 2Z4ZA 3MAVA 1HXCA 1V4IA 4RNQA 4MC8A 4P0VA 5ILIA 3M0GA 4LFVF 4JVJF 1N22A 4NG6A 5EATA 3OYRA 3WCGA 3VJ9A 4LUUA 4KQ5A 2PS5A 3N1VF 2E90A 4F6XA 2E91A 1YYUA 4JXYA 3WCLA 4P0WA 5JA0F 2E93A 1HX9A 4GP1A 1PS1A 2E8WA 4KFAA 1HM7A 4LZ3A 5IM1A 5HNAA 1VG3A 4QXSF 3N5HF 2AELA 3ZOUA 3TFNA 2ZEVA 3QKCA 2E4OA 3VJAA 1WL2A 4NKFA 3WCFA 3TS7A 4DZWA 3WCIA 3DYFA 4Q23A 3KRPA 5DGMF 3WCJA 3WCAA 5IK6A 3CP6A 3RYWA 5B02A 1N1BA 3N1WF 3WEGA 3WEKA 1YJ4A 4XQSF 4EA2A 3KROA 5DHKA 3N0GA 3P8LA 5ILKA 1EZFA 2RAHA 2OA6A 5IK0A 3Q2ZA 5CG5A 3N3DA 3LLWA 3WCEA 5ILDA 5IN8A 4RXCA 1N23A 2AETA 2P1CA 5A0JA 1YHLA 2Z7IA 5IMNA 5ILZA 2I19A 3WJNA 4EA1A 2Z4YA 3ACXA 2Z50A 3LJIA 3NF2A 4KVYA 4LOBA 1YYTA 2F9KF 2AZJA 4N9UA 3VJDA 4DWGA 5ILYA 5IKHA 5JUZF 3ACYA 3IPIA 2Q58A 3AQCB 3EGTA 4LA6A 5DJRF 3WJOA 4DI5A 3SDTA 3PDEA 5DZ2A 2OPMA 1WY0A 3WCMA 1FPSA 3WCCA 4FJQA 3V1VA 3M01A 3WJKA 2ZEUA 3WSAA 3LEEA 3ZL6A 3ICKA 1YYRA 2F8CF 3P41A 4NFKF 5JV0F 3BNXA 3V66A 3ASXA 5JV1F 3VJBA 3LGZB 3Q2QA 2VF6A 3S4JA 4H5CF 5DGNF 4KVDA 4LTVA 4L2XF 3LZ9A 3KRFB 5AYPA 4E1EA 3LMDA 4NKEA 2AZKA 4LZ0A 4PVYF 3LK5A 4OGUA 5DHIA 5IL8A 3N3LF 4NFJF 3SDUA 4DWBA 1WMWA 2Z52A 3VJ8A 5IL3A 2ZCOA 4K10A 4KKMA 1VG6A 4XQRF 2E95A 2Z4XA 3AQ0A 2EWGA 5A0KA 5ER8A 1V4JA 3M02A 3ID0A 3N5JF 3LVSA 5C05A 3EFQA 3P5RA 2Z7HA 3WCDA 1N20A 2Q80A 3LOMA 3LGKA 1N1ZA 3KRAA 3WEJA 5IKAA 2ZCSA 3M9UA 5EROA 5IVGA 4KPDA 4LIXA 3OACB 1UBVA 3P8RA 4ZQ8A 3MZVA 1VG7A 3ZMCA 2ZCRA 1HXAA 4KPJA 5DJVF 5B03A 1V4KA 4KVWA 3RBMA 2Z78A 5EAUA 4NFIF 1YHMA 5A0IA 2Q9YA 5DIQF 4DXJA 2FTZA 2OGDA 4N1ZF 4JYXA 4RXAA 4EA0A 4LFGA 3ICZA 5ILJA 5B0KA 1WL0A 2E8VA 3ICMA 4NUAA 3ZCDA 1YYSA 5E8HA 3SAEA 3NRIA 2J1PA 1RQIA 3OABB 4QPFA 4XQTF 3KRCB 3DYHA 2ONGA 5B00A 5ERMA 2DH4A 5HN8A 4DEMF 1KIYA 3M00A 1KIZA 3WE9A 3W7FA 1V4EA 4RYPA 4JZBA 4KQSA 3WC9A 3NPKA 1UBYA 4LXWA 1RQJA 2PS7A 2Z4VA 3TFPA 3AE0A 3VJEA 2F8ZF 3AQBB 4MC3A 3EZ3A 3PYAA 3WEIA 4LLTA 3PKOA 5DGSF 3N46F 3N0FA 3KRPB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4OMH A;  4RXE A;  3WEF A;  2E8X A;  3WEH A;  4JXN A;  3CKE A;  1N21 A;  2F7M F;  4OKM A;  3WCB A;  3PYB A;  1RTR A;  4MC0 A;  3KRO B;  3WCH A;  4GAX A;  3RYE A;  4PVX F;  5B01 A;  3V1X A;  5H9D A;  5KSX F;  4GP2 A;  5IMI A;  1V4H A;  3Q30 A;  5HN9 A;  1JFG A;  3TFV A;  3VJC A;  2E94 A;  5JV2 F;  5E8K A;  3ADZ A;  2H8O A;  1N24 A;  4OKZ A;  3B7L A;  2AEK A;  3RMG A;  3WSB A;  3NPR A;  4DHD A;  4KUX A;  4KWD A;  3IBA A;  4H5E F;  3SDR A;  2PS4 A;  3G4D A;  4P0X A;  4LTZ A;  1VG4 A;  3Q1O A;  4LA5 A;  4LPH F;  4LLS A;  1UBX A;  3ACW A;  5IK9 A;  2PS6 A;  4E9Z A;  3KRF A;  2PS8 A;  1WL1 A;  4LFE A;  2J1O A;  3ICN A;  4F62 A;  3APZ A;  2ZCQ A;  5CG6 A;  1VG2 A;  5HN7 A;  5B0I A;  3SDV A;  1HM4 A;  2F94 F;  3ZMB A;  2OPN A;  3DYG A;  5E8L A;  4LZC A;  1HXG A;  4FP4 A;  2F89 F;  5DW7 A;  4OMG A;  1YV5 A;  2J5C A;  2E92 A;  4KQU A;  5B0J A;  5ILH A;  2E8T A;  1YYQ A;  1JFA A;  5AHU B;  4JZX A;  1DGP A;  5IMP A;  4E9U A;  5DJP F;  5AFX A;  3TC1 A;  4UMJ A;  4KK2 A;  2ONH A;  2Z4W A;  5I1U A;  5B0M A;  5ERN A;  2QIS A;  2E8U A;  3LSN A;  2F92 F;  4WK5 A;  2FOR A;  3OAC A;  3BNY A;  1YQ7 A;  5B0L A;  3LDW A;  4HD1 A;  1DI1 A;  4GA3 A;  3N49 F;  3G4F A;  1WKZ A;  3N45 F;  1WL3 A;  3P5P A;  3KB9 A;  4KVI A;  3UCA A;  1ZW5 A;  1UBW A;  2ZY1 A;  3KRA B;  2O1O A;  2Q9Z A;  3LG5 A;  5EAS A;  4F6V A;  4H5D F;  1YHK A;  3PH7 A;  2AZL A;  3N6K F;  3QQV A;  3CC9 A;  4LPG F;  3KBK A;  4RXD A;  5AEL A;  3OAB A;  3KRC A;  3SDQ A;  3S9V A;  2Z4Z A;  3MAV A;  1HXC A;  1V4I A;  4RNQ A;  4MC8 A;  4P0V A;  5ILI A;  3M0G A;  4LFV F;  4JVJ F;  1N22 A;  4NG6 A;  5EAT A;  3OYR A;  3WCG A;  3VJ9 A;  4LUU A;  4KQ5 A;  2PS5 A;  3N1V F;  2E90 A;  4F6X A;  2E91 A;  1YYU A;  4JXY A;  3WCL A;  4P0W A;  5JA0 F;  2E93 A;  1HX9 A;  4GP1 A;  1PS1 A;  2E8W A;  4KFA A;  1HM7 A;  4LZ3 A;  5IM1 A;  5HNA A;  1VG3 A;  4QXS F;  3N5H F;  2AEL A;  3ZOU A;  3TFN A;  2ZEV A;  3QKC A;  2E4O A;  3VJA A;  1WL2 A;  4NKF A;  3WCF A;  3TS7 A;  4DZW A;  3WCI A;  3DYF A;  4Q23 A;  3KRP A;  5DGM F;  3WCJ A;  3WCA A;  5IK6 A;  3CP6 A;  3RYW A;  5B02 A;  1N1B A;  3N1W F;  3WEG A;  3WEK A;  1YJ4 A;  4XQS F;  4EA2 A;  3KRO A;  5DHK A;  3N0G A;  3P8L A;  5ILK A;  1EZF A;  2RAH A;  2OA6 A;  5IK0 A;  3Q2Z A;  5CG5 A;  3N3D A;  3LLW A;  3WCE A;  5ILD A;  5IN8 A;  4RXC A;  1N23 A;  2AET A;  2P1C A;  5A0J A;  1YHL A;  2Z7I A;  5IMN A;  5ILZ A;  2I19 A;  3WJN A;  4EA1 A;  2Z4Y A;  3ACX A;  2Z50 A;  3LJI A;  3NF2 A;  4KVY A;  4LOB A;  1YYT A;  2F9K F;  2AZJ A;  4N9U A;  3VJD A;  4DWG A;  5ILY A;  5IKH A;  5JUZ F;  3ACY A;  3IPI A;  2Q58 A;  3AQC B;  3EGT A;  4LA6 A;  5DJR F;  3WJO A;  4DI5 A;  3SDT A;  3PDE A;  5DZ2 A;  2OPM A;  1WY0 A;  3WCM A;  1FPS A;  3WCC A;  4FJQ A;  3V1V A;  3M01 A;  3WJK A;  2ZEU A;  3WSA A;  3LEE A;  3ZL6 A;  3ICK A;  1YYR A;  2F8C F;  3P41 A;  4NFK F;  5JV0 F;  3BNX A;  3V66 A;  3ASX A;  5JV1 F;  3VJB A;  3LGZ B;  3Q2Q A;  2VF6 A;  3S4J A;  4H5C F;  5DGN F;  4KVD A;  4LTV A;  4L2X F;  3LZ9 A;  3KRF B;  5AYP A;  4E1E A;  3LMD A;  4NKE A;  2AZK A;  4LZ0 A;  4PVY F;  3LK5 A;  4OGU A;  5DHI A;  5IL8 A;  3N3L F;  4NFJ F;  3SDU A;  4DWB A;  1WMW A;  2Z52 A;  3VJ8 A;  5IL3 A;  2ZCO A;  4K10 A;  4KKM A;  1VG6 A;  4XQR F;  2E95 A;  2Z4X A;  3AQ0 A;  2EWG A;  5A0K A;  5ER8 A;  1V4J A;  3M02 A;  3ID0 A;  3N5J F;  3LVS A;  5C05 A;  3EFQ A;  3P5R A;  2Z7H A;  3WCD A;  1N20 A;  2Q80 A;  3LOM A;  3LGK A;  1N1Z A;  3KRA A;  3WEJ A;  5IKA A;  2ZCS A;  3M9U A;  5ERO A;  5IVG A;  4KPD A;  4LIX A;  3OAC B;  1UBV A;  3P8R A;  4ZQ8 A;  3MZV A;  1VG7 A;  3ZMC A;  2ZCR A;  1HXA A;  4KPJ A;  5DJV F;  5B03 A;  1V4K A;  4KVW A;  3RBM A;  2Z78 A;  5EAU A;  4NFI F;  1YHM A;  5A0I A;  2Q9Y A;  5DIQ F;  4DXJ A;  2FTZ A;  2OGD A;  4N1Z F;  4JYX A;  4RXA A;  4EA0 A;  4LFG A;  3ICZ A;  5ILJ A;  5B0K A;  1WL0 A;  2E8V A;  3ICM A;  4NUA A;  3ZCD A;  1YYS A;  5E8H A;  3SAE A;  3NRI A;  2J1P A;  1RQI A;  3OAB B;  4QPF A;  4XQT F;  3KRC B;  3DYH A;  2ONG A;  5B00 A;  5ERM A;  2DH4 A;  5HN8 A;  4DEM F;  1KIY A;  3M00 A;  1KIZ A;  3WE9 A;  3W7F A;  1V4E A;  4RYP A;  4JZB A;  4KQS A;  3WC9 A;  3NPK A;  1UBY A;  4LXW A;  1RQJ A;  2PS7 A;  2Z4V A;  3TFP A;  3AE0 A;  3VJE A;  2F8Z F;  3AQB B;  4MC3 A;  3EZ3 A;  3PYA A;  3WEI A;  4LLT A;  3PKO A;  5DGS F;  3N46 F;  3N0F A;  3KRP B; 
#chains in the Genus database with same CATH topology
 4OMH A;  4RXE A;  3WEF A;  2E8X A;  3WEH A;  4JXN A;  3CKE A;  1N21 A;  2F7M F;  4OKM A;  3WCB A;  3PYB A;  1RTR A;  4MC0 A;  3KRO B;  3WCH A;  4GAX A;  3RYE A;  4PVX F;  5B01 A;  3V1X A;  5H9D A;  5KSX F;  4GP2 A;  5IMI A;  1V4H A;  3Q30 A;  5HN9 A;  1JFG A;  3TFV A;  3VJC A;  2E94 A;  5JV2 F;  5E8K A;  3ADZ A;  2H8O A;  1N24 A;  4OKZ A;  3B7L A;  2AEK A;  3RMG A;  3WSB A;  3NPR A;  4DHD A;  4KUX A;  4KWD A;  3IBA A;  4H5E F;  3SDR A;  2PS4 A;  3G4D A;  4P0X A;  4LTZ A;  1VG4 A;  3Q1O A;  4LA5 A;  4LPH F;  4LLS A;  1UBX A;  3ACW A;  5IK9 A;  2PS6 A;  4E9Z A;  3KRF A;  2PS8 A;  1WL1 A;  4LFE A;  2J1O A;  3ICN A;  4F62 A;  3APZ A;  2ZCQ A;  5CG6 A;  1VG2 A;  5HN7 A;  5B0I A;  3SDV A;  1HM4 A;  2F94 F;  3ZMB A;  2OPN A;  3DYG A;  5E8L A;  4LZC A;  1HXG A;  4FP4 A;  2F89 F;  5DW7 A;  4OMG A;  1YV5 A;  2J5C A;  2E92 A;  4KQU A;  5B0J A;  5ILH A;  2E8T A;  1YYQ A;  1JFA A;  5AHU B;  4JZX A;  1DGP A;  5IMP A;  4E9U A;  5DJP F;  5AFX A;  3TC1 A;  4UMJ A;  4KK2 A;  2ONH A;  2Z4W A;  5I1U A;  5B0M A;  5ERN A;  2QIS A;  2E8U A;  3LSN A;  2F92 F;  4WK5 A;  2FOR A;  3OAC A;  3BNY A;  1YQ7 A;  5B0L A;  3LDW A;  4HD1 A;  1DI1 A;  4GA3 A;  3N49 F;  3G4F A;  1WKZ A;  3N45 F;  1WL3 A;  3P5P A;  3KB9 A;  4KVI A;  3UCA A;  1ZW5 A;  1UBW A;  2ZY1 A;  3KRA B;  2O1O A;  2Q9Z A;  3LG5 A;  5EAS A;  4F6V A;  4H5D F;  1YHK A;  3PH7 A;  2AZL A;  3N6K F;  3QQV A;  3CC9 A;  4LPG F;  3KBK A;  4RXD A;  5AEL A;  3OAB A;  3KRC A;  3SDQ A;  3S9V A;  2Z4Z A;  3MAV A;  1HXC A;  1V4I A;  4RNQ A;  4MC8 A;  4P0V A;  5ILI A;  3M0G A;  4LFV F;  4JVJ F;  1N22 A;  4NG6 A;  5EAT A;  3OYR A;  3WCG A;  3VJ9 A;  4LUU A;  4KQ5 A;  2PS5 A;  3N1V F;  2E90 A;  4F6X A;  2E91 A;  1YYU A;  4JXY A;  3WCL A;  4P0W A;  5JA0 F;  2E93 A;  1HX9 A;  4GP1 A;  1PS1 A;  2E8W A;  4KFA A;  1HM7 A;  4LZ3 A;  5IM1 A;  5HNA A;  1VG3 A;  4QXS F;  3N5H F;  2AEL A;  3ZOU A;  3TFN A;  2ZEV A;  3QKC A;  2E4O A;  3VJA A;  1WL2 A;  4NKF A;  3WCF A;  3TS7 A;  4DZW A;  3WCI A;  3DYF A;  4Q23 A;  3KRP A;  5DGM F;  3WCJ A;  3WCA A;  5IK6 A;  3CP6 A;  3RYW A;  5B02 A;  1N1B A;  3N1W F;  3WEG A;  3WEK A;  1YJ4 A;  4XQS F;  4EA2 A;  3KRO A;  5DHK A;  3N0G A;  3P8L A;  5ILK A;  1EZF A;  2RAH A;  2OA6 A;  5IK0 A;  3Q2Z A;  5CG5 A;  3N3D A;  3LLW A;  3WCE A;  5ILD A;  5IN8 A;  4RXC A;  1N23 A;  2AET A;  2P1C A;  5A0J A;  1YHL A;  2Z7I A;  5IMN A;  5ILZ A;  2I19 A;  3WJN A;  4EA1 A;  2Z4Y A;  3ACX A;  2Z50 A;  3LJI A;  3NF2 A;  4KVY A;  4LOB A;  1YYT A;  2F9K F;  2AZJ A;  4N9U A;  3VJD A;  4DWG A;  5ILY A;  5IKH A;  5JUZ F;  3ACY A;  3IPI A;  2Q58 A;  3AQC B;  3EGT A;  4LA6 A;  5DJR F;  3WJO A;  4DI5 A;  3SDT A;  3PDE A;  5DZ2 A;  2OPM A;  1WY0 A;  3WCM A;  1FPS A;  3WCC A;  4FJQ A;  3V1V A;  3M01 A;  3WJK A;  2ZEU A;  3WSA A;  3LEE A;  3ZL6 A;  3ICK A;  1YYR A;  2F8C F;  3P41 A;  4NFK F;  5JV0 F;  3BNX A;  3V66 A;  3ASX A;  5JV1 F;  3VJB A;  3LGZ B;  3Q2Q A;  2VF6 A;  3S4J A;  4H5C F;  5DGN F;  4KVD A;  4LTV A;  4L2X F;  3LZ9 A;  3KRF B;  5AYP A;  4E1E A;  3LMD A;  4NKE A;  2AZK A;  4LZ0 A;  4PVY F;  3LK5 A;  4OGU A;  5DHI A;  5IL8 A;  3N3L F;  4NFJ F;  3SDU A;  4DWB A;  1WMW A;  2Z52 A;  3VJ8 A;  5IL3 A;  2ZCO A;  4K10 A;  4KKM A;  1VG6 A;  4XQR F;  2E95 A;  2Z4X A;  3AQ0 A;  2EWG A;  5A0K A;  5ER8 A;  1V4J A;  3M02 A;  3ID0 A;  3N5J F;  3LVS A;  5C05 A;  3EFQ A;  3P5R A;  2Z7H A;  3WCD A;  1N20 A;  2Q80 A;  3LOM A;  3LGK A;  1N1Z A;  3KRA A;  3WEJ A;  5IKA A;  2ZCS A;  3M9U A;  5ERO A;  5IVG A;  4KPD A;  4LIX A;  3OAC B;  1UBV A;  3P8R A;  4ZQ8 A;  3MZV A;  1VG7 A;  3ZMC A;  2ZCR A;  1HXA A;  4KPJ A;  5DJV F;  5B03 A;  1V4K A;  4KVW A;  3RBM A;  2Z78 A;  5EAU A;  4NFI F;  1YHM A;  5A0I A;  2Q9Y A;  5DIQ F;  4DXJ A;  2FTZ A;  2OGD A;  4N1Z F;  4JYX A;  4RXA A;  4EA0 A;  4LFG A;  3ICZ A;  5ILJ A;  5B0K A;  1WL0 A;  2E8V A;  3ICM A;  4NUA A;  3ZCD A;  1YYS A;  5E8H A;  3SAE A;  3NRI A;  2J1P A;  1RQI A;  3OAB B;  4QPF A;  4XQT F;  3KRC B;  3DYH A;  2ONG A;  5B00 A;  5ERM A;  2DH4 A;  5HN8 A;  4DEM F;  1KIY A;  3M00 A;  1KIZ A;  3WE9 A;  3W7F A;  1V4E A;  4RYP A;  4JZB A;  4KQS A;  3WC9 A;  3NPK A;  1UBY A;  4LXW A;  1RQJ A;  2PS7 A;  2Z4V A;  3TFP A;  3AE0 A;  3VJE A;  2F8Z F;  3AQB B;  4MC3 A;  3EZ3 A;  3PYA A;  3WEI A;  4LLT A;  3PKO A;  5DGS F;  3N46 F;  3N0F A;  3KRP B; 
#chains in the Genus database with same CATH homology
 4OMH A;  4RXE A;  3WEF A;  2E8X A;  3WEH A;  4JXN A;  3CKE A;  1N21 A;  2F7M F;  4OKM A;  3WCB A;  3PYB A;  1RTR A;  4MC0 A;  3KRO B;  3WCH A;  4GAX A;  3RYE A;  4PVX F;  5B01 A;  3V1X A;  5H9D A;  5KSX F;  4GP2 A;  5IMI A;  1V4H A;  3Q30 A;  5HN9 A;  1JFG A;  3TFV A;  3VJC A;  2E94 A;  5JV2 F;  5E8K A;  3ADZ A;  2H8O A;  1N24 A;  4OKZ A;  3B7L A;  2AEK A;  3RMG A;  3WSB A;  3NPR A;  4DHD A;  4KUX A;  4KWD A;  3IBA A;  4H5E F;  3SDR A;  2PS4 A;  3G4D A;  4P0X A;  4LTZ A;  1VG4 A;  3Q1O A;  4LA5 A;  4LPH F;  4LLS A;  1UBX A;  3ACW A;  5IK9 A;  2PS6 A;  4E9Z A;  3KRF A;  2PS8 A;  1WL1 A;  4LFE A;  2J1O A;  3ICN A;  4F62 A;  3APZ A;  2ZCQ A;  5CG6 A;  1VG2 A;  5HN7 A;  5B0I A;  3SDV A;  1HM4 A;  2F94 F;  3ZMB A;  2OPN A;  3DYG A;  5E8L A;  4LZC A;  1HXG A;  4FP4 A;  2F89 F;  5DW7 A;  4OMG A;  1YV5 A;  2J5C A;  2E92 A;  4KQU A;  5B0J A;  5ILH A;  2E8T A;  1YYQ A;  1JFA A;  5AHU B;  4JZX A;  1DGP A;  5IMP A;  4E9U A;  5DJP F;  5AFX A;  3TC1 A;  4UMJ A;  4KK2 A;  2ONH A;  2Z4W A;  5I1U A;  5B0M A;  5ERN A;  2QIS A;  2E8U A;  3LSN A;  2F92 F;  4WK5 A;  2FOR A;  3OAC A;  3BNY A;  1YQ7 A;  5B0L A;  3LDW A;  4HD1 A;  1DI1 A;  4GA3 A;  3N49 F;  3G4F A;  1WKZ A;  3N45 F;  1WL3 A;  3P5P A;  3KB9 A;  4KVI A;  3UCA A;  1ZW5 A;  1UBW A;  2ZY1 A;  3KRA B;  2O1O A;  2Q9Z A;  3LG5 A;  5EAS A;  4F6V A;  4H5D F;  1YHK A;  3PH7 A;  2AZL A;  3N6K F;  3QQV A;  3CC9 A;  4LPG F;  3KBK A;  4RXD A;  5AEL A;  3OAB A;  3KRC A;  3SDQ A;  3S9V A;  2Z4Z A;  3MAV A;  1HXC A;  1V4I A;  4RNQ A;  4MC8 A;  4P0V A;  5ILI A;  3M0G A;  4LFV F;  4JVJ F;  1N22 A;  4NG6 A;  5EAT A;  3OYR A;  3WCG A;  3VJ9 A;  4LUU A;  4KQ5 A;  2PS5 A;  3N1V F;  2E90 A;  4F6X A;  2E91 A;  1YYU A;  4JXY A;  3WCL A;  4P0W A;  5JA0 F;  2E93 A;  1HX9 A;  4GP1 A;  1PS1 A;  2E8W A;  4KFA A;  1HM7 A;  4LZ3 A;  5IM1 A;  5HNA A;  1VG3 A;  4QXS F;  3N5H F;  2AEL A;  3ZOU A;  3TFN A;  2ZEV A;  3QKC A;  2E4O A;  3VJA A;  1WL2 A;  4NKF A;  3WCF A;  3TS7 A;  4DZW A;  3WCI A;  3DYF A;  4Q23 A;  3KRP A;  5DGM F;  3WCJ A;  3WCA A;  5IK6 A;  3CP6 A;  3RYW A;  5B02 A;  1N1B A;  3N1W F;  3WEG A;  3WEK A;  1YJ4 A;  4XQS F;  4EA2 A;  3KRO A;  5DHK A;  3N0G A;  3P8L A;  5ILK A;  1EZF A;  2RAH A;  2OA6 A;  5IK0 A;  3Q2Z A;  5CG5 A;  3N3D A;  3LLW A;  3WCE A;  5ILD A;  5IN8 A;  4RXC A;  1N23 A;  2AET A;  2P1C A;  5A0J A;  1YHL A;  2Z7I A;  5IMN A;  5ILZ A;  2I19 A;  3WJN A;  4EA1 A;  2Z4Y A;  3ACX A;  2Z50 A;  3LJI A;  3NF2 A;  4KVY A;  4LOB A;  1YYT A;  2F9K F;  2AZJ A;  4N9U A;  3VJD A;  4DWG A;  5ILY A;  5IKH A;  5JUZ F;  3ACY A;  3IPI A;  2Q58 A;  3AQC B;  3EGT A;  4LA6 A;  5DJR F;  3WJO A;  4DI5 A;  3SDT A;  3PDE A;  5DZ2 A;  2OPM A;  1WY0 A;  3WCM A;  1FPS A;  3WCC A;  4FJQ A;  3V1V A;  3M01 A;  3WJK A;  2ZEU A;  3WSA A;  3LEE A;  3ZL6 A;  3ICK A;  1YYR A;  2F8C F;  3P41 A;  4NFK F;  5JV0 F;  3BNX A;  3V66 A;  3ASX A;  5JV1 F;  3VJB A;  3LGZ B;  3Q2Q A;  2VF6 A;  3S4J A;  4H5C F;  5DGN F;  4KVD A;  4LTV A;  4L2X F;  3LZ9 A;  3KRF B;  5AYP A;  4E1E A;  3LMD A;  4NKE A;  2AZK A;  4LZ0 A;  4PVY F;  3LK5 A;  4OGU A;  5DHI A;  5IL8 A;  3N3L F;  4NFJ F;  3SDU A;  4DWB A;  1WMW A;  2Z52 A;  3VJ8 A;  5IL3 A;  2ZCO A;  4K10 A;  4KKM A;  1VG6 A;  4XQR F;  2E95 A;  2Z4X A;  3AQ0 A;  2EWG A;  5A0K A;  5ER8 A;  1V4J A;  3M02 A;  3ID0 A;  3N5J F;  3LVS A;  5C05 A;  3EFQ A;  3P5R A;  2Z7H A;  3WCD A;  1N20 A;  2Q80 A;  3LOM A;  3LGK A;  1N1Z A;  3KRA A;  3WEJ A;  5IKA A;  2ZCS A;  3M9U A;  5ERO A;  5IVG A;  4KPD A;  4LIX A;  3OAC B;  1UBV A;  3P8R A;  4ZQ8 A;  3MZV A;  1VG7 A;  3ZMC A;  2ZCR A;  1HXA A;  4KPJ A;  5DJV F;  5B03 A;  1V4K A;  4KVW A;  3RBM A;  2Z78 A;  5EAU A;  4NFI F;  1YHM A;  5A0I A;  2Q9Y A;  5DIQ F;  4DXJ A;  2FTZ A;  2OGD A;  4N1Z F;  4JYX A;  4RXA A;  4EA0 A;  4LFG A;  3ICZ A;  5ILJ A;  5B0K A;  1WL0 A;  2E8V A;  3ICM A;  4NUA A;  3ZCD A;  1YYS A;  5E8H A;  3SAE A;  3NRI A;  2J1P A;  1RQI A;  3OAB B;  4QPF A;  4XQT F;  3KRC B;  3DYH A;  2ONG A;  5B00 A;  5ERM A;  2DH4 A;  5HN8 A;  4DEM F;  1KIY A;  3M00 A;  1KIZ A;  3WE9 A;  3W7F A;  1V4E A;  4RYP A;  4JZB A;  4KQS A;  3WC9 A;  3NPK A;  1UBY A;  4LXW A;  1RQJ A;  2PS7 A;  2Z4V A;  3TFP A;  3AE0 A;  3VJE A;  2F8Z F;  3AQB B;  4MC3 A;  3EZ3 A;  3PYA A;  3WEI A;  4LLT A;  3PKO A;  5DGS F;  3N46 F;  3N0F A;  3KRP B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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