4DWBA

Crystal structure of trypanosoma cruzi farnesyl diphosphate synthase in complex with [2-(n-pentylamino)ethane-1,1-diyl]bisphosphonic acid and mg2+
Total Genus 146
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
146
sequence length
361
structure length
361
Chain Sequence
MASMERFLSVYDEVQAFLLDQLQSKYEIDPNRARYLRIMMDTTCLGGKYFRGMTVVNVAEGFLAVTQHDEATKERILHDACVGGWMIEFLQAHYLVEDDIMDGSVMRRGKPCWYRFPGVTTQCAINDGIILKSWTQIMAWHYFADRPFLKDLLCLFQKVDYATAVGQMYDVTSMCDSNKLDPEVAQPMTTDFAEFTPAIYKRIVKYKTTFYTYLLPLVMGLFVSEAAASVEMNLVERVAHLIGEYFQVQDDVMDCFTPPEQLGKVGTDIEDAKCSWLAVTFLGKANAAQVAEFKANYGDKDPAKVAVVKRLYSEANLQADFAAYEAEVVREVESLIEQLKVKSPTFAESVAVVWEKTHKRK
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Transferase/transferase inhibitor
molecule keywords Farnesyl pyrophosphate synthase
publication title Design, synthesis, calorimetry, and crystallographic analysis of 2-alkylaminoethyl-1,1-bisphosphonates as inhibitors of Trypanosoma cruzi farnesyl diphosphate synthase.
pubmed doi rcsb
source organism Trypanosoma cruzi
total genus 146
structure length 361
sequence length 361
ec nomenclature ec 2.5.1.10: (2E,6E)-farnesyl diphosphate synthase.
pdb deposition date 2012-02-24

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00348 polyprenyl_synt Polyprenyl synthetase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.600.10 Mainly Alpha Orthogonal Bundle Farnesyl Diphosphate Synthase Farnesyl Diphosphate Synthase 4dwbA00
4LFVF 2F8ZF 4OMGA 4F62A 5ILJA 1RQJA 4OGUA 3LGKA 4H5CF 1PS1A 2PS6A 5A0JA 5ILHA 3PKOA 4EA2A 3DYGA 1VG3A 1WL2A 5B0MA 3WJOA 5B0JA 3WCGA 5DGSF 2ZEUA 3ASXA 3LVSA 3VJCA 3APZA 4LUUA 3WCIA 3ZMCA 3TC1A 2FTZA 4QPFA 4KK2A 2ZEVA 5IK9A 4PVYF 5AELA 3RYEA 3AQCB 1V4IA 4XQTF 3M9UA 4OMHA 5B02A 2E91A 5EASA 3WE9A 4DXJA 4LTVA 5E8LA 4KQUA 4NG6A 3N45F 3AE0A 3Q30A 4FJQA 5ER8A 4RXCA 2Q58A 2P1CA 1N22A 2RAHA 2ONGA 2VF6A 3MAVA 3NF2A 1YHMA 2Z4YA 4L2XF 4KUXA 3UCAA 2Z4ZA 3MZVA 4RXEA 5I1UA 3KRAA 3B7LA 4DHDA 3ACWA 2OGDA 4NUAA 4OKZA 2E4OA 3N0GA 3WEFA 3S9VA 2E8UA 1HM7A 1RTRA 4KKMA 2OPMA 4KQ5A 3NRIA 5B0KA 3N6KF 4MC3A 2AZJA 4XQSF 1V4JA 5HNAA 2Z7IA 4P0XA 4F6VA 4KVYA 2Z7HA 1YYTA 3CC9A 1N23A 5A0IA 3P5PA 3LG5A 5JV1F 4LPHF 4DI5A 4LOBA 4KVDA 2PS8A 3ZOUA 2ZCQA 4KPJA 3TFNA 4JYXA 4LFGA 2AEKA 5AYPA 2ZY1A 4JZXA 3WCDA 4HD1A 3WEGA 1V4KA 3LK5A 4JZBA 5ILYA 1DGPA 3N3LF 1JFAA 2I19A 4LA6A 2QISA 5AFXA 3QQVA 1JFGA 2Z4VA 4NKEA 4RXDA 1YYSA 5ERNA 5IL8A 5C05A 3LZ9A 3WEIA 3WEKA 3NPKA 4QXSF 3WCLA 5ILIA 5IM1A 5H9DA 3OACA 3OACB 2PS5A 3N49F 5IL3A 3Q1OA 3WSBA 2EWGA 2F7MF 2Z50A 4LFEA 2Q9ZA 5A0KA 3WEJA 3Q2QA 3ZMBA 1FPSA 4DEMF 3ID0A 5HN7A 4DWBA 5HN9A 3V1XA 5CG6A 1HXGA 3BNXA 4JXYA 3P8RA 2F9KF 4RNQA 5DIQF 5JA0F 3VJ9A 5E8KA 5EROA 3ICNA 3PYBA 1UBWA 4NFKF 1VG4A 4P0WA 3LJIA 3RYWA 3S4JA 2F8CF 3N5JF 4GP1A 3AQBB 4FP4A 5DGMF 5DJPF 3VJDA 4LZ0A 4RYPA 5E8HA 1DI1A 4JVJF 5DGNF 3OYRA 4UMJA 3M0GA 1HXAA 4WK5A 3WC9A 5IMIA 3WCCA 2Z4XA 5JV0F 3N1WF 3SDTA 4OKMA 4N1ZF 2AELA 4KVWA 2J1PA 1RQIA 2ZCRA 4LZCA 3M01A 3KRFB 1ZW5A 5IMNA 3PH7A 4RXAA 3CP6A 1VG7A 2F94F 3WCHA 3WJNA 2E93A 3AQ0A 3SDQA 5DZ2A 4H5DF 3LDWA 2ZCSA 3EFQA 1VG2A 3KRPB 3KRPA 2Z52A 1N1ZA 3NPRA 5ILKA 2E8WA 2J5CA 4DWGA 1UBVA 3VJEA 1V4HA 3LOMA 3G4DA 4E1EA 5EAUA 1YV5A 4P0VA 5DHKA 4MC8A 5AHUB 3M00A 2FORA 1N24A 4LLTA 1WL0A 2F89F 4XQRF 1YJ4A 3WEHA 4DZWA 3VJAA 4K10A 3VJ8A 5DJRF 1EZFA 4KQSA 2H8OA 5JV2F 5DW7A 3IPIA 3V66A 3CKEA 3PDEA 2PS4A 3VJBA 2Z78A 3DYFA 3WCAA 3N5HF 1HXCA 3N3DA 2AETA 3SDUA 3BNYA 1KIZA 4PVXF 3LMDA 3WSAA 2DH4A 3KRCA 3KRCB 1YHKA 1N20A 4MC0A 4E9UA 4EA0A 1HM4A 4LXWA 5JUZF 2E8TA 2PS7A 2E95A 3WCEA 5IVGA 1YHLA 1UBYA 1YYUA 5IKAA 4LTZA 4LA5A 3TFVA 3ZL6A 3M02A 3KROA 3KROB 4ZQ8A 3P41A 4LIXA 2OA6A 5KSXF 4N9UA 3ACXA 4F6XA 4NKFA 1N21A 2E90A 4NFJF 5DHIA 3KBKA 3EZ3A 3LSNA 3LEEA 5ERMA 3P8LA 3SDVA 2E92A 1WMWA 3P5RA 4GAXA 4KVIA 3WCMA 5B00A 2AZLA 1VG6A 2O1OA 3Q2ZA 5B03A 4H5EF 4GA3A 2E94A 1YQ7A 2F92F 3N0FA 5IKHA 2AZKA 3SDRA 3KB9A 4KWDA 5HN8A 5IMPA 1KIYA 4E9ZA 3WCJA 1YYQA 1HX9A 3RBMA 3ZCDA 3KRFA 3ICZA 3KRAB 5IK0A 3N46F 3QKCA 1N1BA 3IBAA 5B0LA 1WY0A 3OABA 3OABB 3W7FA 3TS7A 2Q80A 3WCFA 2ZCOA 2J1OA 3SAEA 3V1VA 5EATA 1UBXA 5CG5A 4LLSA 4LPGF 2OPNA 5IN8A 3TFPA 3G4FA 2ONHA 3ACYA 4EA1A 1WL3A 3LGZB 4LZ3A 1WL1A 4Q23A 2Z4WA 3RMGA 4KPDA 3LLWA 5B01A 3PYAA 1YYRA 2Q9YA 1WKZA 3ICKA 4JXNA 5ILDA 2E8XA 5DJVF 3ICMA 3ADZA 3WJKA 3DYHA 1V4EA 3WCBA 2E8VA 3N1VF 4NFIF 4KFAA 5B0IA 5ILZA 5IK6A 4GP2A 3EGTA
chains in the Genus database with same CATH superfamily
4LFVF 2F8ZF 4OMGA 4F62A 5ILJA 1RQJA 4OGUA 3LGKA 4H5CF 1PS1A 2PS6A 5A0JA 5ILHA 3PKOA 4EA2A 3DYGA 1VG3A 1WL2A 5B0MA 3WJOA 5B0JA 3WCGA 5DGSF 2ZEUA 3ASXA 3LVSA 3VJCA 3APZA 4LUUA 3WCIA 3ZMCA 3TC1A 2FTZA 4QPFA 4KK2A 2ZEVA 5IK9A 4PVYF 5AELA 3RYEA 3AQCB 1V4IA 4XQTF 3M9UA 4OMHA 5B02A 2E91A 5EASA 3WE9A 4DXJA 4LTVA 5E8LA 4KQUA 4NG6A 3N45F 3AE0A 3Q30A 4FJQA 5ER8A 4RXCA 2Q58A 2P1CA 1N22A 2RAHA 2ONGA 2VF6A 3MAVA 3NF2A 1YHMA 2Z4YA 4L2XF 4KUXA 3UCAA 2Z4ZA 3MZVA 4RXEA 5I1UA 3KRAA 3B7LA 4DHDA 3ACWA 2OGDA 4NUAA 4OKZA 2E4OA 3N0GA 3WEFA 3S9VA 2E8UA 1HM7A 1RTRA 4KKMA 2OPMA 4KQ5A 3NRIA 5B0KA 3N6KF 4MC3A 2AZJA 4XQSF 1V4JA 5HNAA 2Z7IA 4P0XA 4F6VA 4KVYA 2Z7HA 1YYTA 3CC9A 1N23A 5A0IA 3P5PA 3LG5A 5JV1F 4LPHF 4DI5A 4LOBA 4KVDA 2PS8A 3ZOUA 2ZCQA 4KPJA 3TFNA 4JYXA 4LFGA 2AEKA 5AYPA 2ZY1A 4JZXA 3WCDA 4HD1A 3WEGA 1V4KA 3LK5A 4JZBA 5ILYA 1DGPA 3N3LF 1JFAA 2I19A 4LA6A 2QISA 5AFXA 3QQVA 1JFGA 2Z4VA 4NKEA 4RXDA 1YYSA 5ERNA 5IL8A 5C05A 3LZ9A 3WEIA 3WEKA 3NPKA 4QXSF 3WCLA 5ILIA 5IM1A 5H9DA 3OACA 3OACB 2PS5A 3N49F 5IL3A 3Q1OA 3WSBA 2EWGA 2F7MF 2Z50A 4LFEA 2Q9ZA 5A0KA 3WEJA 3Q2QA 3ZMBA 1FPSA 4DEMF 3ID0A 5HN7A 4DWBA 5HN9A 3V1XA 5CG6A 1HXGA 3BNXA 4JXYA 3P8RA 2F9KF 4RNQA 5DIQF 5JA0F 3VJ9A 5E8KA 5EROA 3ICNA 3PYBA 1UBWA 4NFKF 1VG4A 4P0WA 3LJIA 3RYWA 3S4JA 2F8CF 3N5JF 4GP1A 3AQBB 4FP4A 5DGMF 5DJPF 3VJDA 4LZ0A 4RYPA 5E8HA 1DI1A 4JVJF 5DGNF 3OYRA 4UMJA 3M0GA 1HXAA 4WK5A 3WC9A 5IMIA 3WCCA 2Z4XA 5JV0F 3N1WF 3SDTA 4OKMA 4N1ZF 2AELA 4KVWA 2J1PA 1RQIA 2ZCRA 4LZCA 3M01A 3KRFB 1ZW5A 5IMNA 3PH7A 4RXAA 3CP6A 1VG7A 2F94F 3WCHA 3WJNA 2E93A 3AQ0A 3SDQA 5DZ2A 4H5DF 3LDWA 2ZCSA 3EFQA 1VG2A 3KRPB 3KRPA 2Z52A 1N1ZA 3NPRA 5ILKA 2E8WA 2J5CA 4DWGA 1UBVA 3VJEA 1V4HA 3LOMA 3G4DA 4E1EA 5EAUA 1YV5A 4P0VA 5DHKA 4MC8A 5AHUB 3M00A 2FORA 1N24A 4LLTA 1WL0A 2F89F 4XQRF 1YJ4A 3WEHA 4DZWA 3VJAA 4K10A 3VJ8A 5DJRF 1EZFA 4KQSA 2H8OA 5JV2F 5DW7A 3IPIA 3V66A 3CKEA 3PDEA 2PS4A 3VJBA 2Z78A 3DYFA 3WCAA 3N5HF 1HXCA 3N3DA 2AETA 3SDUA 3BNYA 1KIZA 4PVXF 3LMDA 3WSAA 2DH4A 3KRCA 3KRCB 1YHKA 1N20A 4MC0A 4E9UA 4EA0A 1HM4A 4LXWA 5JUZF 2E8TA 2PS7A 2E95A 3WCEA 5IVGA 1YHLA 1UBYA 1YYUA 5IKAA 4LTZA 4LA5A 3TFVA 3ZL6A 3M02A 3KROA 3KROB 4ZQ8A 3P41A 4LIXA 2OA6A 5KSXF 4N9UA 3ACXA 4F6XA 4NKFA 1N21A 2E90A 4NFJF 5DHIA 3KBKA 3EZ3A 3LSNA 3LEEA 5ERMA 3P8LA 3SDVA 2E92A 1WMWA 3P5RA 4GAXA 4KVIA 3WCMA 5B00A 2AZLA 1VG6A 2O1OA 3Q2ZA 5B03A 4H5EF 4GA3A 2E94A 1YQ7A 2F92F 3N0FA 5IKHA 2AZKA 3SDRA 3KB9A 4KWDA 5HN8A 5IMPA 1KIYA 4E9ZA 3WCJA 1YYQA 1HX9A 3RBMA 3ZCDA 3KRFA 3ICZA 3KRAB 5IK0A 3N46F 3QKCA 1N1BA 3IBAA 5B0LA 1WY0A 3OABA 3OABB 3W7FA 3TS7A 2Q80A 3WCFA 2ZCOA 2J1OA 3SAEA 3V1VA 5EATA 1UBXA 5CG5A 4LLSA 4LPGF 2OPNA 5IN8A 3TFPA 3G4FA 2ONHA 3ACYA 4EA1A 1WL3A 3LGZB 4LZ3A 1WL1A 4Q23A 2Z4WA 3RMGA 4KPDA 3LLWA 5B01A 3PYAA 1YYRA 2Q9YA 1WKZA 3ICKA 4JXNA 5ILDA 2E8XA 5DJVF 3ICMA 3ADZA 3WJKA 3DYHA 1V4EA 3WCBA 2E8VA 3N1VF 4NFIF 4KFAA 5B0IA 5ILZA 5IK6A 4GP2A 3EGTA
chains in the Genus database with same CATH topology
4LFVF 2F8ZF 4OMGA 4F62A 5ILJA 1RQJA 4OGUA 3LGKA 4H5CF 1PS1A 2PS6A 5A0JA 5ILHA 3PKOA 4EA2A 3DYGA 1VG3A 1WL2A 5B0MA 3WJOA 5B0JA 3WCGA 5DGSF 2ZEUA 3ASXA 3LVSA 3VJCA 3APZA 4LUUA 3WCIA 3ZMCA 3TC1A 2FTZA 4QPFA 4KK2A 2ZEVA 5IK9A 4PVYF 5AELA 3RYEA 3AQCB 1V4IA 4XQTF 3M9UA 4OMHA 5B02A 2E91A 5EASA 3WE9A 4DXJA 4LTVA 5E8LA 4KQUA 4NG6A 3N45F 3AE0A 3Q30A 4FJQA 5ER8A 4RXCA 2Q58A 2P1CA 1N22A 2RAHA 2ONGA 2VF6A 3MAVA 3NF2A 1YHMA 2Z4YA 4L2XF 4KUXA 3UCAA 2Z4ZA 3MZVA 4RXEA 5I1UA 3KRAA 3B7LA 4DHDA 3ACWA 2OGDA 4NUAA 4OKZA 2E4OA 3N0GA 3WEFA 3S9VA 2E8UA 1HM7A 1RTRA 4KKMA 2OPMA 4KQ5A 3NRIA 5B0KA 3N6KF 4MC3A 2AZJA 4XQSF 1V4JA 5HNAA 2Z7IA 4P0XA 4F6VA 4KVYA 2Z7HA 1YYTA 3CC9A 1N23A 5A0IA 3P5PA 3LG5A 5JV1F 4LPHF 4DI5A 4LOBA 4KVDA 2PS8A 3ZOUA 2ZCQA 4KPJA 3TFNA 4JYXA 4LFGA 2AEKA 5AYPA 2ZY1A 4JZXA 3WCDA 4HD1A 3WEGA 1V4KA 3LK5A 4JZBA 5ILYA 1DGPA 3N3LF 1JFAA 2I19A 4LA6A 2QISA 5AFXA 3QQVA 1JFGA 2Z4VA 4NKEA 4RXDA 1YYSA 5ERNA 5IL8A 5C05A 3LZ9A 3WEIA 3WEKA 3NPKA 4QXSF 3WCLA 5ILIA 5IM1A 5H9DA 3OACA 3OACB 2PS5A 3N49F 5IL3A 3Q1OA 3WSBA 2EWGA 2F7MF 2Z50A 4LFEA 2Q9ZA 5A0KA 3WEJA 3Q2QA 3ZMBA 1FPSA 4DEMF 3ID0A 5HN7A 4DWBA 5HN9A 3V1XA 5CG6A 1HXGA 3BNXA 4JXYA 3P8RA 2F9KF 4RNQA 5DIQF 5JA0F 3VJ9A 5E8KA 5EROA 3ICNA 3PYBA 1UBWA 4NFKF 1VG4A 4P0WA 3LJIA 3RYWA 3S4JA 2F8CF 3N5JF 4GP1A 3AQBB 4FP4A 5DGMF 5DJPF 3VJDA 4LZ0A 4RYPA 5E8HA 1DI1A 4JVJF 5DGNF 3OYRA 4UMJA 3M0GA 1HXAA 4WK5A 3WC9A 5IMIA 3WCCA 2Z4XA 5JV0F 3N1WF 3SDTA 4OKMA 4N1ZF 2AELA 4KVWA 2J1PA 1RQIA 2ZCRA 4LZCA 3M01A 3KRFB 1ZW5A 5IMNA 3PH7A 4RXAA 3CP6A 1VG7A 2F94F 3WCHA 3WJNA 2E93A 3AQ0A 3SDQA 5DZ2A 4H5DF 3LDWA 2ZCSA 3EFQA 1VG2A 3KRPB 3KRPA 2Z52A 1N1ZA 3NPRA 5ILKA 2E8WA 2J5CA 4DWGA 1UBVA 3VJEA 1V4HA 3LOMA 3G4DA 4E1EA 5EAUA 1YV5A 4P0VA 5DHKA 4MC8A 5AHUB 3M00A 2FORA 1N24A 4LLTA 1WL0A 2F89F 4XQRF 1YJ4A 3WEHA 4DZWA 3VJAA 4K10A 3VJ8A 5DJRF 1EZFA 4KQSA 2H8OA 5JV2F 5DW7A 3IPIA 3V66A 3CKEA 3PDEA 2PS4A 3VJBA 2Z78A 3DYFA 3WCAA 3N5HF 1HXCA 3N3DA 2AETA 3SDUA 3BNYA 1KIZA 4PVXF 3LMDA 3WSAA 2DH4A 3KRCA 3KRCB 1YHKA 1N20A 4MC0A 4E9UA 4EA0A 1HM4A 4LXWA 5JUZF 2E8TA 2PS7A 2E95A 3WCEA 5IVGA 1YHLA 1UBYA 1YYUA 5IKAA 4LTZA 4LA5A 3TFVA 3ZL6A 3M02A 3KROA 3KROB 4ZQ8A 3P41A 4LIXA 2OA6A 5KSXF 4N9UA 3ACXA 4F6XA 4NKFA 1N21A 2E90A 4NFJF 5DHIA 3KBKA 3EZ3A 3LSNA 3LEEA 5ERMA 3P8LA 3SDVA 2E92A 1WMWA 3P5RA 4GAXA 4KVIA 3WCMA 5B00A 2AZLA 1VG6A 2O1OA 3Q2ZA 5B03A 4H5EF 4GA3A 2E94A 1YQ7A 2F92F 3N0FA 5IKHA 2AZKA 3SDRA 3KB9A 4KWDA 5HN8A 5IMPA 1KIYA 4E9ZA 3WCJA 1YYQA 1HX9A 3RBMA 3ZCDA 3KRFA 3ICZA 3KRAB 5IK0A 3N46F 3QKCA 1N1BA 3IBAA 5B0LA 1WY0A 3OABA 3OABB 3W7FA 3TS7A 2Q80A 3WCFA 2ZCOA 2J1OA 3SAEA 3V1VA 5EATA 1UBXA 5CG5A 4LLSA 4LPGF 2OPNA 5IN8A 3TFPA 3G4FA 2ONHA 3ACYA 4EA1A 1WL3A 3LGZB 4LZ3A 1WL1A 4Q23A 2Z4WA 3RMGA 4KPDA 3LLWA 5B01A 3PYAA 1YYRA 2Q9YA 1WKZA 3ICKA 4JXNA 5ILDA 2E8XA 5DJVF 3ICMA 3ADZA 3WJKA 3DYHA 1V4EA 3WCBA 2E8VA 3N1VF 4NFIF 4KFAA 5B0IA 5ILZA 5IK6A 4GP2A 3EGTA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4LFV F;  2F8Z F;  4OMG A;  4F62 A;  5ILJ A;  1RQJ A;  4OGU A;  3LGK A;  4H5C F;  1PS1 A;  2PS6 A;  5A0J A;  5ILH A;  3PKO A;  4EA2 A;  3DYG A;  1VG3 A;  1WL2 A;  5B0M A;  3WJO A;  5B0J A;  3WCG A;  5DGS F;  2ZEU A;  3ASX A;  3LVS A;  3VJC A;  3APZ A;  4LUU A;  3WCI A;  3ZMC A;  3TC1 A;  2FTZ A;  4QPF A;  4KK2 A;  2ZEV A;  5IK9 A;  4PVY F;  5AEL A;  3RYE A;  3AQC B;  1V4I A;  4XQT F;  3M9U A;  4OMH A;  5B02 A;  2E91 A;  5EAS A;  3WE9 A;  4DXJ A;  4LTV A;  5E8L A;  4KQU A;  4NG6 A;  3N45 F;  3AE0 A;  3Q30 A;  4FJQ A;  5ER8 A;  4RXC A;  2Q58 A;  2P1C A;  1N22 A;  2RAH A;  2ONG A;  2VF6 A;  3MAV A;  3NF2 A;  1YHM A;  2Z4Y A;  4L2X F;  4KUX A;  3UCA A;  2Z4Z A;  3MZV A;  4RXE A;  5I1U A;  3KRA A;  3B7L A;  4DHD A;  3ACW A;  2OGD A;  4NUA A;  4OKZ A;  2E4O A;  3N0G A;  3WEF A;  3S9V A;  2E8U A;  1HM7 A;  1RTR A;  4KKM A;  2OPM A;  4KQ5 A;  3NRI A;  5B0K A;  3N6K F;  4MC3 A;  2AZJ A;  4XQS F;  1V4J A;  5HNA A;  2Z7I A;  4P0X A;  4F6V A;  4KVY A;  2Z7H A;  1YYT A;  3CC9 A;  1N23 A;  5A0I A;  3P5P A;  3LG5 A;  5JV1 F;  4LPH F;  4DI5 A;  4LOB A;  4KVD A;  2PS8 A;  3ZOU A;  2ZCQ A;  4KPJ A;  3TFN A;  4JYX A;  4LFG A;  2AEK A;  5AYP A;  2ZY1 A;  4JZX A;  3WCD A;  4HD1 A;  3WEG A;  1V4K A;  3LK5 A;  4JZB A;  5ILY A;  1DGP A;  3N3L F;  1JFA A;  2I19 A;  4LA6 A;  2QIS A;  5AFX A;  3QQV A;  1JFG A;  2Z4V A;  4NKE A;  4RXD A;  1YYS A;  5ERN A;  5IL8 A;  5C05 A;  3LZ9 A;  3WEI A;  3WEK A;  3NPK A;  4QXS F;  3WCL A;  5ILI A;  5IM1 A;  5H9D A;  3OAC A;  3OAC B;  2PS5 A;  3N49 F;  5IL3 A;  3Q1O A;  3WSB A;  2EWG A;  2F7M F;  2Z50 A;  4LFE A;  2Q9Z A;  5A0K A;  3WEJ A;  3Q2Q A;  3ZMB A;  1FPS A;  4DEM F;  3ID0 A;  5HN7 A;  4DWB A;  5HN9 A;  3V1X A;  5CG6 A;  1HXG A;  3BNX A;  4JXY A;  3P8R A;  2F9K F;  4RNQ A;  5DIQ F;  5JA0 F;  3VJ9 A;  5E8K A;  5ERO A;  3ICN A;  3PYB A;  1UBW A;  4NFK F;  1VG4 A;  4P0W A;  3LJI A;  3RYW A;  3S4J A;  2F8C F;  3N5J F;  4GP1 A;  3AQB B;  4FP4 A;  5DGM F;  5DJP F;  3VJD A;  4LZ0 A;  4RYP A;  5E8H A;  1DI1 A;  4JVJ F;  5DGN F;  3OYR A;  4UMJ A;  3M0G A;  1HXA A;  4WK5 A;  3WC9 A;  5IMI A;  3WCC A;  2Z4X A;  5JV0 F;  3N1W F;  3SDT A;  4OKM A;  4N1Z F;  2AEL A;  4KVW A;  2J1P A;  1RQI A;  2ZCR A;  4LZC A;  3M01 A;  3KRF B;  1ZW5 A;  5IMN A;  3PH7 A;  4RXA A;  3CP6 A;  1VG7 A;  2F94 F;  3WCH A;  3WJN A;  2E93 A;  3AQ0 A;  3SDQ A;  5DZ2 A;  4H5D F;  3LDW A;  2ZCS A;  3EFQ A;  1VG2 A;  3KRP B;  3KRP A;  2Z52 A;  1N1Z A;  3NPR A;  5ILK A;  2E8W A;  2J5C A;  4DWG A;  1UBV A;  3VJE A;  1V4H A;  3LOM A;  3G4D A;  4E1E A;  5EAU A;  1YV5 A;  4P0V A;  5DHK A;  4MC8 A;  5AHU B;  3M00 A;  2FOR A;  1N24 A;  4LLT A;  1WL0 A;  2F89 F;  4XQR F;  1YJ4 A;  3WEH A;  4DZW A;  3VJA A;  4K10 A;  3VJ8 A;  5DJR F;  1EZF A;  4KQS A;  2H8O A;  5JV2 F;  5DW7 A;  3IPI A;  3V66 A;  3CKE A;  3PDE A;  2PS4 A;  3VJB A;  2Z78 A;  3DYF A;  3WCA A;  3N5H F;  1HXC A;  3N3D A;  2AET A;  3SDU A;  3BNY A;  1KIZ A;  4PVX F;  3LMD A;  3WSA A;  2DH4 A;  3KRC A;  3KRC B;  1YHK A;  1N20 A;  4MC0 A;  4E9U A;  4EA0 A;  1HM4 A;  4LXW A;  5JUZ F;  2E8T A;  2PS7 A;  2E95 A;  3WCE A;  5IVG A;  1YHL A;  1UBY A;  1YYU A;  5IKA A;  4LTZ A;  4LA5 A;  3TFV A;  3ZL6 A;  3M02 A;  3KRO A;  3KRO B;  4ZQ8 A;  3P41 A;  4LIX A;  2OA6 A;  5KSX F;  4N9U A;  3ACX A;  4F6X A;  4NKF A;  1N21 A;  2E90 A;  4NFJ F;  5DHI A;  3KBK A;  3EZ3 A;  3LSN A;  3LEE A;  5ERM A;  3P8L A;  3SDV A;  2E92 A;  1WMW A;  3P5R A;  4GAX A;  4KVI A;  3WCM A;  5B00 A;  2AZL A;  1VG6 A;  2O1O A;  3Q2Z A;  5B03 A;  4H5E F;  4GA3 A;  2E94 A;  1YQ7 A;  2F92 F;  3N0F A;  5IKH A;  2AZK A;  3SDR A;  3KB9 A;  4KWD A;  5HN8 A;  5IMP A;  1KIY A;  4E9Z A;  3WCJ A;  1YYQ A;  1HX9 A;  3RBM A;  3ZCD A;  3KRF A;  3ICZ A;  3KRA B;  5IK0 A;  3N46 F;  3QKC A;  1N1B A;  3IBA A;  5B0L A;  1WY0 A;  3OAB A;  3OAB B;  3W7F A;  3TS7 A;  2Q80 A;  3WCF A;  2ZCO A;  2J1O A;  3SAE A;  3V1V A;  5EAT A;  1UBX A;  5CG5 A;  4LLS A;  4LPG F;  2OPN A;  5IN8 A;  3TFP A;  3G4F A;  2ONH A;  3ACY A;  4EA1 A;  1WL3 A;  3LGZ B;  4LZ3 A;  1WL1 A;  4Q23 A;  2Z4W A;  3RMG A;  4KPD A;  3LLW A;  5B01 A;  3PYA A;  1YYR A;  2Q9Y A;  1WKZ A;  3ICK A;  4JXN A;  5ILD A;  2E8X A;  5DJV F;  3ICM A;  3ADZ A;  3WJK A;  3DYH A;  1V4E A;  3WCB A;  2E8V A;  3N1V F;  4NFI F;  4KFA A;  5B0I A;  5ILZ A;  5IK6 A;  4GP2 A;  3EGT A; 
#chains in the Genus database with same CATH topology
 4LFV F;  2F8Z F;  4OMG A;  4F62 A;  5ILJ A;  1RQJ A;  4OGU A;  3LGK A;  4H5C F;  1PS1 A;  2PS6 A;  5A0J A;  5ILH A;  3PKO A;  4EA2 A;  3DYG A;  1VG3 A;  1WL2 A;  5B0M A;  3WJO A;  5B0J A;  3WCG A;  5DGS F;  2ZEU A;  3ASX A;  3LVS A;  3VJC A;  3APZ A;  4LUU A;  3WCI A;  3ZMC A;  3TC1 A;  2FTZ A;  4QPF A;  4KK2 A;  2ZEV A;  5IK9 A;  4PVY F;  5AEL A;  3RYE A;  3AQC B;  1V4I A;  4XQT F;  3M9U A;  4OMH A;  5B02 A;  2E91 A;  5EAS A;  3WE9 A;  4DXJ A;  4LTV A;  5E8L A;  4KQU A;  4NG6 A;  3N45 F;  3AE0 A;  3Q30 A;  4FJQ A;  5ER8 A;  4RXC A;  2Q58 A;  2P1C A;  1N22 A;  2RAH A;  2ONG A;  2VF6 A;  3MAV A;  3NF2 A;  1YHM A;  2Z4Y A;  4L2X F;  4KUX A;  3UCA A;  2Z4Z A;  3MZV A;  4RXE A;  5I1U A;  3KRA A;  3B7L A;  4DHD A;  3ACW A;  2OGD A;  4NUA A;  4OKZ A;  2E4O A;  3N0G A;  3WEF A;  3S9V A;  2E8U A;  1HM7 A;  1RTR A;  4KKM A;  2OPM A;  4KQ5 A;  3NRI A;  5B0K A;  3N6K F;  4MC3 A;  2AZJ A;  4XQS F;  1V4J A;  5HNA A;  2Z7I A;  4P0X A;  4F6V A;  4KVY A;  2Z7H A;  1YYT A;  3CC9 A;  1N23 A;  5A0I A;  3P5P A;  3LG5 A;  5JV1 F;  4LPH F;  4DI5 A;  4LOB A;  4KVD A;  2PS8 A;  3ZOU A;  2ZCQ A;  4KPJ A;  3TFN A;  4JYX A;  4LFG A;  2AEK A;  5AYP A;  2ZY1 A;  4JZX A;  3WCD A;  4HD1 A;  3WEG A;  1V4K A;  3LK5 A;  4JZB A;  5ILY A;  1DGP A;  3N3L F;  1JFA A;  2I19 A;  4LA6 A;  2QIS A;  5AFX A;  3QQV A;  1JFG A;  2Z4V A;  4NKE A;  4RXD A;  1YYS A;  5ERN A;  5IL8 A;  5C05 A;  3LZ9 A;  3WEI A;  3WEK A;  3NPK A;  4QXS F;  3WCL A;  5ILI A;  5IM1 A;  5H9D A;  3OAC A;  3OAC B;  2PS5 A;  3N49 F;  5IL3 A;  3Q1O A;  3WSB A;  2EWG A;  2F7M F;  2Z50 A;  4LFE A;  2Q9Z A;  5A0K A;  3WEJ A;  3Q2Q A;  3ZMB A;  1FPS A;  4DEM F;  3ID0 A;  5HN7 A;  4DWB A;  5HN9 A;  3V1X A;  5CG6 A;  1HXG A;  3BNX A;  4JXY A;  3P8R A;  2F9K F;  4RNQ A;  5DIQ F;  5JA0 F;  3VJ9 A;  5E8K A;  5ERO A;  3ICN A;  3PYB A;  1UBW A;  4NFK F;  1VG4 A;  4P0W A;  3LJI A;  3RYW A;  3S4J A;  2F8C F;  3N5J F;  4GP1 A;  3AQB B;  4FP4 A;  5DGM F;  5DJP F;  3VJD A;  4LZ0 A;  4RYP A;  5E8H A;  1DI1 A;  4JVJ F;  5DGN F;  3OYR A;  4UMJ A;  3M0G A;  1HXA A;  4WK5 A;  3WC9 A;  5IMI A;  3WCC A;  2Z4X A;  5JV0 F;  3N1W F;  3SDT A;  4OKM A;  4N1Z F;  2AEL A;  4KVW A;  2J1P A;  1RQI A;  2ZCR A;  4LZC A;  3M01 A;  3KRF B;  1ZW5 A;  5IMN A;  3PH7 A;  4RXA A;  3CP6 A;  1VG7 A;  2F94 F;  3WCH A;  3WJN A;  2E93 A;  3AQ0 A;  3SDQ A;  5DZ2 A;  4H5D F;  3LDW A;  2ZCS A;  3EFQ A;  1VG2 A;  3KRP B;  3KRP A;  2Z52 A;  1N1Z A;  3NPR A;  5ILK A;  2E8W A;  2J5C A;  4DWG A;  1UBV A;  3VJE A;  1V4H A;  3LOM A;  3G4D A;  4E1E A;  5EAU A;  1YV5 A;  4P0V A;  5DHK A;  4MC8 A;  5AHU B;  3M00 A;  2FOR A;  1N24 A;  4LLT A;  1WL0 A;  2F89 F;  4XQR F;  1YJ4 A;  3WEH A;  4DZW A;  3VJA A;  4K10 A;  3VJ8 A;  5DJR F;  1EZF A;  4KQS A;  2H8O A;  5JV2 F;  5DW7 A;  3IPI A;  3V66 A;  3CKE A;  3PDE A;  2PS4 A;  3VJB A;  2Z78 A;  3DYF A;  3WCA A;  3N5H F;  1HXC A;  3N3D A;  2AET A;  3SDU A;  3BNY A;  1KIZ A;  4PVX F;  3LMD A;  3WSA A;  2DH4 A;  3KRC A;  3KRC B;  1YHK A;  1N20 A;  4MC0 A;  4E9U A;  4EA0 A;  1HM4 A;  4LXW A;  5JUZ F;  2E8T A;  2PS7 A;  2E95 A;  3WCE A;  5IVG A;  1YHL A;  1UBY A;  1YYU A;  5IKA A;  4LTZ A;  4LA5 A;  3TFV A;  3ZL6 A;  3M02 A;  3KRO A;  3KRO B;  4ZQ8 A;  3P41 A;  4LIX A;  2OA6 A;  5KSX F;  4N9U A;  3ACX A;  4F6X A;  4NKF A;  1N21 A;  2E90 A;  4NFJ F;  5DHI A;  3KBK A;  3EZ3 A;  3LSN A;  3LEE A;  5ERM A;  3P8L A;  3SDV A;  2E92 A;  1WMW A;  3P5R A;  4GAX A;  4KVI A;  3WCM A;  5B00 A;  2AZL A;  1VG6 A;  2O1O A;  3Q2Z A;  5B03 A;  4H5E F;  4GA3 A;  2E94 A;  1YQ7 A;  2F92 F;  3N0F A;  5IKH A;  2AZK A;  3SDR A;  3KB9 A;  4KWD A;  5HN8 A;  5IMP A;  1KIY A;  4E9Z A;  3WCJ A;  1YYQ A;  1HX9 A;  3RBM A;  3ZCD A;  3KRF A;  3ICZ A;  3KRA B;  5IK0 A;  3N46 F;  3QKC A;  1N1B A;  3IBA A;  5B0L A;  1WY0 A;  3OAB A;  3OAB B;  3W7F A;  3TS7 A;  2Q80 A;  3WCF A;  2ZCO A;  2J1O A;  3SAE A;  3V1V A;  5EAT A;  1UBX A;  5CG5 A;  4LLS A;  4LPG F;  2OPN A;  5IN8 A;  3TFP A;  3G4F A;  2ONH A;  3ACY A;  4EA1 A;  1WL3 A;  3LGZ B;  4LZ3 A;  1WL1 A;  4Q23 A;  2Z4W A;  3RMG A;  4KPD A;  3LLW A;  5B01 A;  3PYA A;  1YYR A;  2Q9Y A;  1WKZ A;  3ICK A;  4JXN A;  5ILD A;  2E8X A;  5DJV F;  3ICM A;  3ADZ A;  3WJK A;  3DYH A;  1V4E A;  3WCB A;  2E8V A;  3N1V F;  4NFI F;  4KFA A;  5B0I A;  5ILZ A;  5IK6 A;  4GP2 A;  3EGT A; 
#chains in the Genus database with same CATH homology
 4LFV F;  2F8Z F;  4OMG A;  4F62 A;  5ILJ A;  1RQJ A;  4OGU A;  3LGK A;  4H5C F;  1PS1 A;  2PS6 A;  5A0J A;  5ILH A;  3PKO A;  4EA2 A;  3DYG A;  1VG3 A;  1WL2 A;  5B0M A;  3WJO A;  5B0J A;  3WCG A;  5DGS F;  2ZEU A;  3ASX A;  3LVS A;  3VJC A;  3APZ A;  4LUU A;  3WCI A;  3ZMC A;  3TC1 A;  2FTZ A;  4QPF A;  4KK2 A;  2ZEV A;  5IK9 A;  4PVY F;  5AEL A;  3RYE A;  3AQC B;  1V4I A;  4XQT F;  3M9U A;  4OMH A;  5B02 A;  2E91 A;  5EAS A;  3WE9 A;  4DXJ A;  4LTV A;  5E8L A;  4KQU A;  4NG6 A;  3N45 F;  3AE0 A;  3Q30 A;  4FJQ A;  5ER8 A;  4RXC A;  2Q58 A;  2P1C A;  1N22 A;  2RAH A;  2ONG A;  2VF6 A;  3MAV A;  3NF2 A;  1YHM A;  2Z4Y A;  4L2X F;  4KUX A;  3UCA A;  2Z4Z A;  3MZV A;  4RXE A;  5I1U A;  3KRA A;  3B7L A;  4DHD A;  3ACW A;  2OGD A;  4NUA A;  4OKZ A;  2E4O A;  3N0G A;  3WEF A;  3S9V A;  2E8U A;  1HM7 A;  1RTR A;  4KKM A;  2OPM A;  4KQ5 A;  3NRI A;  5B0K A;  3N6K F;  4MC3 A;  2AZJ A;  4XQS F;  1V4J A;  5HNA A;  2Z7I A;  4P0X A;  4F6V A;  4KVY A;  2Z7H A;  1YYT A;  3CC9 A;  1N23 A;  5A0I A;  3P5P A;  3LG5 A;  5JV1 F;  4LPH F;  4DI5 A;  4LOB A;  4KVD A;  2PS8 A;  3ZOU A;  2ZCQ A;  4KPJ A;  3TFN A;  4JYX A;  4LFG A;  2AEK A;  5AYP A;  2ZY1 A;  4JZX A;  3WCD A;  4HD1 A;  3WEG A;  1V4K A;  3LK5 A;  4JZB A;  5ILY A;  1DGP A;  3N3L F;  1JFA A;  2I19 A;  4LA6 A;  2QIS A;  5AFX A;  3QQV A;  1JFG A;  2Z4V A;  4NKE A;  4RXD A;  1YYS A;  5ERN A;  5IL8 A;  5C05 A;  3LZ9 A;  3WEI A;  3WEK A;  3NPK A;  4QXS F;  3WCL A;  5ILI A;  5IM1 A;  5H9D A;  3OAC A;  3OAC B;  2PS5 A;  3N49 F;  5IL3 A;  3Q1O A;  3WSB A;  2EWG A;  2F7M F;  2Z50 A;  4LFE A;  2Q9Z A;  5A0K A;  3WEJ A;  3Q2Q A;  3ZMB A;  1FPS A;  4DEM F;  3ID0 A;  5HN7 A;  4DWB A;  5HN9 A;  3V1X A;  5CG6 A;  1HXG A;  3BNX A;  4JXY A;  3P8R A;  2F9K F;  4RNQ A;  5DIQ F;  5JA0 F;  3VJ9 A;  5E8K A;  5ERO A;  3ICN A;  3PYB A;  1UBW A;  4NFK F;  1VG4 A;  4P0W A;  3LJI A;  3RYW A;  3S4J A;  2F8C F;  3N5J F;  4GP1 A;  3AQB B;  4FP4 A;  5DGM F;  5DJP F;  3VJD A;  4LZ0 A;  4RYP A;  5E8H A;  1DI1 A;  4JVJ F;  5DGN F;  3OYR A;  4UMJ A;  3M0G A;  1HXA A;  4WK5 A;  3WC9 A;  5IMI A;  3WCC A;  2Z4X A;  5JV0 F;  3N1W F;  3SDT A;  4OKM A;  4N1Z F;  2AEL A;  4KVW A;  2J1P A;  1RQI A;  2ZCR A;  4LZC A;  3M01 A;  3KRF B;  1ZW5 A;  5IMN A;  3PH7 A;  4RXA A;  3CP6 A;  1VG7 A;  2F94 F;  3WCH A;  3WJN A;  2E93 A;  3AQ0 A;  3SDQ A;  5DZ2 A;  4H5D F;  3LDW A;  2ZCS A;  3EFQ A;  1VG2 A;  3KRP B;  3KRP A;  2Z52 A;  1N1Z A;  3NPR A;  5ILK A;  2E8W A;  2J5C A;  4DWG A;  1UBV A;  3VJE A;  1V4H A;  3LOM A;  3G4D A;  4E1E A;  5EAU A;  1YV5 A;  4P0V A;  5DHK A;  4MC8 A;  5AHU B;  3M00 A;  2FOR A;  1N24 A;  4LLT A;  1WL0 A;  2F89 F;  4XQR F;  1YJ4 A;  3WEH A;  4DZW A;  3VJA A;  4K10 A;  3VJ8 A;  5DJR F;  1EZF A;  4KQS A;  2H8O A;  5JV2 F;  5DW7 A;  3IPI A;  3V66 A;  3CKE A;  3PDE A;  2PS4 A;  3VJB A;  2Z78 A;  3DYF A;  3WCA A;  3N5H F;  1HXC A;  3N3D A;  2AET A;  3SDU A;  3BNY A;  1KIZ A;  4PVX F;  3LMD A;  3WSA A;  2DH4 A;  3KRC A;  3KRC B;  1YHK A;  1N20 A;  4MC0 A;  4E9U A;  4EA0 A;  1HM4 A;  4LXW A;  5JUZ F;  2E8T A;  2PS7 A;  2E95 A;  3WCE A;  5IVG A;  1YHL A;  1UBY A;  1YYU A;  5IKA A;  4LTZ A;  4LA5 A;  3TFV A;  3ZL6 A;  3M02 A;  3KRO A;  3KRO B;  4ZQ8 A;  3P41 A;  4LIX A;  2OA6 A;  5KSX F;  4N9U A;  3ACX A;  4F6X A;  4NKF A;  1N21 A;  2E90 A;  4NFJ F;  5DHI A;  3KBK A;  3EZ3 A;  3LSN A;  3LEE A;  5ERM A;  3P8L A;  3SDV A;  2E92 A;  1WMW A;  3P5R A;  4GAX A;  4KVI A;  3WCM A;  5B00 A;  2AZL A;  1VG6 A;  2O1O A;  3Q2Z A;  5B03 A;  4H5E F;  4GA3 A;  2E94 A;  1YQ7 A;  2F92 F;  3N0F A;  5IKH A;  2AZK A;  3SDR A;  3KB9 A;  4KWD A;  5HN8 A;  5IMP A;  1KIY A;  4E9Z A;  3WCJ A;  1YYQ A;  1HX9 A;  3RBM A;  3ZCD A;  3KRF A;  3ICZ A;  3KRA B;  5IK0 A;  3N46 F;  3QKC A;  1N1B A;  3IBA A;  5B0L A;  1WY0 A;  3OAB A;  3OAB B;  3W7F A;  3TS7 A;  2Q80 A;  3WCF A;  2ZCO A;  2J1O A;  3SAE A;  3V1V A;  5EAT A;  1UBX A;  5CG5 A;  4LLS A;  4LPG F;  2OPN A;  5IN8 A;  3TFP A;  3G4F A;  2ONH A;  3ACY A;  4EA1 A;  1WL3 A;  3LGZ B;  4LZ3 A;  1WL1 A;  4Q23 A;  2Z4W A;  3RMG A;  4KPD A;  3LLW A;  5B01 A;  3PYA A;  1YYR A;  2Q9Y A;  1WKZ A;  3ICK A;  4JXN A;  5ILD A;  2E8X A;  5DJV F;  3ICM A;  3ADZ A;  3WJK A;  3DYH A;  1V4E A;  3WCB A;  2E8V A;  3N1V F;  4NFI F;  4KFA A;  5B0I A;  5ILZ A;  5IK6 A;  4GP2 A;  3EGT A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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