4DWGA

Crystal structure of trypanosome cruzi farnesyl diphosphate synthase in complex with [2-(n-heptylamino)ethane-1,1-diyl]bisphosphonic acid and mg2+
Total Genus 150
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
150
sequence length
361
structure length
361
Chain Sequence
MASMERFLSVYDEVQAFLLDQLQSKYEIDPNRARYLRIMMDTTCLGGKYFRGMTVVNVAEGFLAVTQHDEATKERILHDACVGGWMIEFLQAHYLVEDDIMDGSVMRRGKPCWYRFPGVTTQCAINDGIILKSWTQIMAWHYFADRPFLKDLLCLFQKVDYATAVGQMYDVTSMCDSNKLDPEVAQPMTTDFAEFTPAIYKRIVKYKTTFYTYLLPLVMGLFVSEAAASVEMNLVERVAHLIGEYFQVQDDVMDCFTPPEQLGKVGTDIEDAKCSWLAVTFLGKANAAQVAEFKANYGDKDPAKVAVVKRLYSEANLQADFAAYEAEVVREVESLIEQLKVKSPTFAESVAVVWEKTHKRK
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title Design, synthesis, calorimetry, and crystallographic analysis of 2-alkylaminoethyl-1,1-bisphosphonates as inhibitors of Trypanosoma cruzi farnesyl diphosphate synthase.
pubmed doi rcsb
molecule tags Transferase/transferase inhibitor
source organism Trypanosoma cruzi
molecule keywords Farnesyl pyrophosphate synthase
total genus 150
structure length 361
sequence length 361
ec nomenclature ec 2.5.1.10: (2E,6E)-farnesyl diphosphate synthase.
pdb deposition date 2012-02-24

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00348 polyprenyl_synt Polyprenyl synthetase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.600.10 Mainly Alpha Orthogonal Bundle Farnesyl Diphosphate Synthase Farnesyl Diphosphate Synthase 4dwgA00
5AELA 3ASXA 2FORA 4E9UA 3PYBA 4N1ZF 5JUZF 3WEFA 4QPFA 4LPGF 3WCJA 4KQ5A 3LMDA 3WCIA 5IKAA 4LPHF 3WSBA 4Q23A 4MC3A 4OMGA 3AQ0A 5IK6A 5DGSF 3VJDA 4MC8A 3ZMCA 2PS5A 3LGKA 3PDEA 4LLTA 3WCEA 3Q1OA 3VJ8A 1YQ7A 1YHLA 2ZCRA 5B02A 3LOMA 2PS8A 3MAVA 3NPRA 3QKCA 5IK0A 3CC9A 3KRPA 3TFVA 2Z7IA 3APZA 3WEHA 2E92A 4MC0A 4DZWA 4F6XA 3WCFA 1HX9A 1YJ4A 3SDRA 2E94A 2J5CA 2ZCSA 3WJKA 1YHKA 4JXYA 2AELA 3M9UA 3OACB 2FTZA 3PKOA 3ID0A 4KVIA 3ICNA 4DXJA 2F8ZF 5DJVF 3KRCB 2DH4A 3CKEA 1WY0A 4RXCA 2E93A 1VG4A 4UMJA 1HM7A 3N5JF 5DZ2A 3ICMA 1N22A 4GP2A 5E8KA 3RBMA 3N6KF 4EA2A 4QXSF 2ONGA 3QQVA 4LZ0A 5IL8A 5EAUA 3TFPA 3ZL6A 5B0KA 4DHDA 5E8LA 1V4JA 5DIQF 4LZ3A 1N1ZA 5EASA 3KBKA 2O1OA 3LSNA 2AZJA 2QISA 2Z4ZA 5B0MA 3VJCA 4OKMA 3N1VF 4LA6A 5ILHA 4RYPA 1EZFA 1N20A 3KRAA 3WEJA 1YYUA 2J1PA 3N5HF 3LJIA 4JVJF 1JFGA 2OGDA 4P0WA 4LTZA 2ZEVA 3Q30A 3BNYA 2OPMA 2H8OA 2E8WA 1WMWA 5B0JA 1FPSA 5JA0F 3ACXA 3ZOUA 2EWGA 4FJQA 4JZXA 4K10A 2E8VA 5IVGA 5IMPA 5IK9A 5EROA 3VJAA 3TS7A 3Q2ZA 4JZBA 4RXAA 2PS4A 4PVYF 5B00A 4XQSF 5A0KA 3N49F 2Z4YA 3LLWA 4DWBA 1VG7A 3RMGA 3N0GA 3P8RA 3WE9A 4NFIF 3ZMBA 3MZVA 3SDTA 1DI1A 3M0GA 3LEEA 1WL3A 3KROA 2OA6A 5ILKA 3DYFA 4LUUA 3LDWA 2E95A 3ICKA 2ONHA 5I1UA 1N1BA 5IM1A 3P5PA 2Z7HA 4DWGA 3W7FA 5C05A 3IPIA 4LZCA 1VG2A 2PS6A 3AE0A 3S4JA 3KRPB 4NFKF 1YYQA 4LXWA 3WEKA 4P0XA 3WJOA 3WCMA 4LOBA 4LFGA 3N1WF 4DEMF 5DHKA 3WEGA 5AHUB 3VJBA 4LFVF 3CP6A 4OGUA 4ZQ8A 2VF6A 4LIXA 1PS1A 2AZKA 3SDVA 3KRFA 2F9KF 4KUXA 5CG5A 2PS7A 4H5CF 3WCHA 1HXAA 2F92F 3N3DA 3OABA 5HN9A 5ILYA 2I19A 4KKMA 3WEIA 2F7MF 3LZ9A 4KQSA 5IMIA 4RNQA 4KQUA 5B01A 4NUAA 2E8XA 4OKZA 2ZCOA 4XQTF 1YYTA 1HM4A 3BNXA 2Z4XA 3G4FA 1VG6A 3ZCDA 2Q80A 4H5EF 4GP1A 3P8LA 3OYRA 3KRAB 2F89F 1UBVA 3M01A 1WKZA 4L2XF 1KIZA 2P1CA 1KIYA 3EGTA 1JFAA 2ZEUA 4F6VA 4NKFA 4LTVA 3EZ3A 5AYPA 5KSXF 2E91A 5HN8A 3PYAA 3RYEA 3TFNA 3S9VA 4KFAA 5AFXA 1UBXA 4EA0A 3M00A 3NF2A 3LGZB 1YYSA 5IKHA 4WK5A 5ILJA 1N24A 3LG5A 1WL2A 3EFQA 3KROB 4OMHA 3V1VA 5CG6A 4KVDA 3ADZA 4LLSA 3N0FA 3V66A 3WCGA 1ZW5A 1N23A 2Q9ZA 1RQIA 3LK5A 3WCDA 2AZLA 3WCBA 1WL0A 3ICZA 5B0LA 3WJNA 5EATA 1V4IA 3VJ9A 4JYXA 2E4OA 4PVXF 5ILDA 3WC9A 5JV0F 1N21A 3TC1A 2AETA 2E90A 2J1OA 3IBAA 3VJEA 1WL1A 5JV1F 3M02A 4FP4A 3SDUA 5A0IA 1DGPA 2F94F 5DJRF 5IN8A 4EA1A 3WCLA 5B03A 2Q9YA 4H5DF 3AQCB 3WCAA 3AQBB 2E8TA 3KRFB 4LA5A 2ZY1A 5DHIA 3ACYA 3OACA 2E8UA 2Z4WA 3PH7A 4DI5A 4KK2A 5H9DA 4E9ZA 4XQRF 1RQJA 4KPJA 5HN7A 2Z4VA 3OABB 1HXGA 3KRCA 3V1XA 4GA3A 3WSAA 4JXNA 3RYWA 5B0IA 3DYHA 5DJPF 5JV2F 5DGMF 3N3LF 3NPKA 3WCCA 5DW7A 2AEKA 5ER8A 4NFJF 3SDQA 4KWDA 5A0JA 4LFEA 5ERMA 4GAXA 2Q58A 1RTRA 3NRIA 1HXCA 3DYGA 4NKEA 1V4KA 4F62A 5ILZA 3SAEA 1VG3A 1YV5A 3N45F 5IL3A 1V4HA 4P0VA 4KVYA 2RAHA 4HD1A 1UBYA 3KB9A 4KPDA 2Z52A 3N46F 2Z78A 2ZCQA 1YYRA 5DGNF 5IMNA 3Q2QA 4KVWA 5ILIA 4NG6A 4RXEA 4N9UA 2OPNA 4E1EA 3UCAA 3G4DA 5ERNA 1YHMA 3ACWA 3B7LA 3LVSA 3P5RA 5HNAA 2F8CF 5E8HA 1UBWA 1V4EA 3P41A 2Z50A 4RXDA
chains in the Genus database with same CATH superfamily
5AELA 3ASXA 2FORA 4E9UA 3PYBA 4N1ZF 5JUZF 3WEFA 4QPFA 4LPGF 3WCJA 4KQ5A 3LMDA 3WCIA 5IKAA 4LPHF 3WSBA 4Q23A 4MC3A 4OMGA 3AQ0A 5IK6A 5DGSF 3VJDA 4MC8A 3ZMCA 2PS5A 3LGKA 3PDEA 4LLTA 3WCEA 3Q1OA 3VJ8A 1YQ7A 1YHLA 2ZCRA 5B02A 3LOMA 2PS8A 3MAVA 3NPRA 3QKCA 5IK0A 3CC9A 3KRPA 3TFVA 2Z7IA 3APZA 3WEHA 2E92A 4MC0A 4DZWA 4F6XA 3WCFA 1HX9A 1YJ4A 3SDRA 2E94A 2J5CA 2ZCSA 3WJKA 1YHKA 4JXYA 2AELA 3M9UA 3OACB 2FTZA 3PKOA 3ID0A 4KVIA 3ICNA 4DXJA 2F8ZF 5DJVF 3KRCB 2DH4A 3CKEA 1WY0A 4RXCA 2E93A 1VG4A 4UMJA 1HM7A 3N5JF 5DZ2A 3ICMA 1N22A 4GP2A 5E8KA 3RBMA 3N6KF 4EA2A 4QXSF 2ONGA 3QQVA 4LZ0A 5IL8A 5EAUA 3TFPA 3ZL6A 5B0KA 4DHDA 5E8LA 1V4JA 5DIQF 4LZ3A 1N1ZA 5EASA 3KBKA 2O1OA 3LSNA 2AZJA 2QISA 2Z4ZA 5B0MA 3VJCA 4OKMA 3N1VF 4LA6A 5ILHA 4RYPA 1EZFA 1N20A 3KRAA 3WEJA 1YYUA 2J1PA 3N5HF 3LJIA 4JVJF 1JFGA 2OGDA 4P0WA 4LTZA 2ZEVA 3Q30A 3BNYA 2OPMA 2H8OA 2E8WA 1WMWA 5B0JA 1FPSA 5JA0F 3ACXA 3ZOUA 2EWGA 4FJQA 4JZXA 4K10A 2E8VA 5IVGA 5IMPA 5IK9A 5EROA 3VJAA 3TS7A 3Q2ZA 4JZBA 4RXAA 2PS4A 4PVYF 5B00A 4XQSF 5A0KA 3N49F 2Z4YA 3LLWA 4DWBA 1VG7A 3RMGA 3N0GA 3P8RA 3WE9A 4NFIF 3ZMBA 3MZVA 3SDTA 1DI1A 3M0GA 3LEEA 1WL3A 3KROA 2OA6A 5ILKA 3DYFA 4LUUA 3LDWA 2E95A 3ICKA 2ONHA 5I1UA 1N1BA 5IM1A 3P5PA 2Z7HA 4DWGA 3W7FA 5C05A 3IPIA 4LZCA 1VG2A 2PS6A 3AE0A 3S4JA 3KRPB 4NFKF 1YYQA 4LXWA 3WEKA 4P0XA 3WJOA 3WCMA 4LOBA 4LFGA 3N1WF 4DEMF 5DHKA 3WEGA 5AHUB 3VJBA 4LFVF 3CP6A 4OGUA 4ZQ8A 2VF6A 4LIXA 1PS1A 2AZKA 3SDVA 3KRFA 2F9KF 4KUXA 5CG5A 2PS7A 4H5CF 3WCHA 1HXAA 2F92F 3N3DA 3OABA 5HN9A 5ILYA 2I19A 4KKMA 3WEIA 2F7MF 3LZ9A 4KQSA 5IMIA 4RNQA 4KQUA 5B01A 4NUAA 2E8XA 4OKZA 2ZCOA 4XQTF 1YYTA 1HM4A 3BNXA 2Z4XA 3G4FA 1VG6A 3ZCDA 2Q80A 4H5EF 4GP1A 3P8LA 3OYRA 3KRAB 2F89F 1UBVA 3M01A 1WKZA 4L2XF 1KIZA 2P1CA 1KIYA 3EGTA 1JFAA 2ZEUA 4F6VA 4NKFA 4LTVA 3EZ3A 5AYPA 5KSXF 2E91A 5HN8A 3PYAA 3RYEA 3TFNA 3S9VA 4KFAA 5AFXA 1UBXA 4EA0A 3M00A 3NF2A 3LGZB 1YYSA 5IKHA 4WK5A 5ILJA 1N24A 3LG5A 1WL2A 3EFQA 3KROB 4OMHA 3V1VA 5CG6A 4KVDA 3ADZA 4LLSA 3N0FA 3V66A 3WCGA 1ZW5A 1N23A 2Q9ZA 1RQIA 3LK5A 3WCDA 2AZLA 3WCBA 1WL0A 3ICZA 5B0LA 3WJNA 5EATA 1V4IA 3VJ9A 4JYXA 2E4OA 4PVXF 5ILDA 3WC9A 5JV0F 1N21A 3TC1A 2AETA 2E90A 2J1OA 3IBAA 3VJEA 1WL1A 5JV1F 3M02A 4FP4A 3SDUA 5A0IA 1DGPA 2F94F 5DJRF 5IN8A 4EA1A 3WCLA 5B03A 2Q9YA 4H5DF 3AQCB 3WCAA 3AQBB 2E8TA 3KRFB 4LA5A 2ZY1A 5DHIA 3ACYA 3OACA 2E8UA 2Z4WA 3PH7A 4DI5A 4KK2A 5H9DA 4E9ZA 4XQRF 1RQJA 4KPJA 5HN7A 2Z4VA 3OABB 1HXGA 3KRCA 3V1XA 4GA3A 3WSAA 4JXNA 3RYWA 5B0IA 3DYHA 5DJPF 5JV2F 5DGMF 3N3LF 3NPKA 3WCCA 5DW7A 2AEKA 5ER8A 4NFJF 3SDQA 4KWDA 5A0JA 4LFEA 5ERMA 4GAXA 2Q58A 1RTRA 3NRIA 1HXCA 3DYGA 4NKEA 1V4KA 4F62A 5ILZA 3SAEA 1VG3A 1YV5A 3N45F 5IL3A 1V4HA 4P0VA 4KVYA 2RAHA 4HD1A 1UBYA 3KB9A 4KPDA 2Z52A 3N46F 2Z78A 2ZCQA 1YYRA 5DGNF 5IMNA 3Q2QA 4KVWA 5ILIA 4NG6A 4RXEA 4N9UA 2OPNA 4E1EA 3UCAA 3G4DA 5ERNA 1YHMA 3ACWA 3B7LA 3LVSA 3P5RA 5HNAA 2F8CF 5E8HA 1UBWA 1V4EA 3P41A 2Z50A 4RXDA
chains in the Genus database with same CATH topology
5AELA 3ASXA 2FORA 4E9UA 3PYBA 4N1ZF 5JUZF 3WEFA 4QPFA 4LPGF 3WCJA 4KQ5A 3LMDA 3WCIA 5IKAA 4LPHF 3WSBA 4Q23A 4MC3A 4OMGA 3AQ0A 5IK6A 5DGSF 3VJDA 4MC8A 3ZMCA 2PS5A 3LGKA 3PDEA 4LLTA 3WCEA 3Q1OA 3VJ8A 1YQ7A 1YHLA 2ZCRA 5B02A 3LOMA 2PS8A 3MAVA 3NPRA 3QKCA 5IK0A 3CC9A 3KRPA 3TFVA 2Z7IA 3APZA 3WEHA 2E92A 4MC0A 4DZWA 4F6XA 3WCFA 1HX9A 1YJ4A 3SDRA 2E94A 2J5CA 2ZCSA 3WJKA 1YHKA 4JXYA 2AELA 3M9UA 3OACB 2FTZA 3PKOA 3ID0A 4KVIA 3ICNA 4DXJA 2F8ZF 5DJVF 3KRCB 2DH4A 3CKEA 1WY0A 4RXCA 2E93A 1VG4A 4UMJA 1HM7A 3N5JF 5DZ2A 3ICMA 1N22A 4GP2A 5E8KA 3RBMA 3N6KF 4EA2A 4QXSF 2ONGA 3QQVA 4LZ0A 5IL8A 5EAUA 3TFPA 3ZL6A 5B0KA 4DHDA 5E8LA 1V4JA 5DIQF 4LZ3A 1N1ZA 5EASA 3KBKA 2O1OA 3LSNA 2AZJA 2QISA 2Z4ZA 5B0MA 3VJCA 4OKMA 3N1VF 4LA6A 5ILHA 4RYPA 1EZFA 1N20A 3KRAA 3WEJA 1YYUA 2J1PA 3N5HF 3LJIA 4JVJF 1JFGA 2OGDA 4P0WA 4LTZA 2ZEVA 3Q30A 3BNYA 2OPMA 2H8OA 2E8WA 1WMWA 5B0JA 1FPSA 5JA0F 3ACXA 3ZOUA 2EWGA 4FJQA 4JZXA 4K10A 2E8VA 5IVGA 5IMPA 5IK9A 5EROA 3VJAA 3TS7A 3Q2ZA 4JZBA 4RXAA 2PS4A 4PVYF 5B00A 4XQSF 5A0KA 3N49F 2Z4YA 3LLWA 4DWBA 1VG7A 3RMGA 3N0GA 3P8RA 3WE9A 4NFIF 3ZMBA 3MZVA 3SDTA 1DI1A 3M0GA 3LEEA 1WL3A 3KROA 2OA6A 5ILKA 3DYFA 4LUUA 3LDWA 2E95A 3ICKA 2ONHA 5I1UA 1N1BA 5IM1A 3P5PA 2Z7HA 4DWGA 3W7FA 5C05A 3IPIA 4LZCA 1VG2A 2PS6A 3AE0A 3S4JA 3KRPB 4NFKF 1YYQA 4LXWA 3WEKA 4P0XA 3WJOA 3WCMA 4LOBA 4LFGA 3N1WF 4DEMF 5DHKA 3WEGA 5AHUB 3VJBA 4LFVF 3CP6A 4OGUA 4ZQ8A 2VF6A 4LIXA 1PS1A 2AZKA 3SDVA 3KRFA 2F9KF 4KUXA 5CG5A 2PS7A 4H5CF 3WCHA 1HXAA 2F92F 3N3DA 3OABA 5HN9A 5ILYA 2I19A 4KKMA 3WEIA 2F7MF 3LZ9A 4KQSA 5IMIA 4RNQA 4KQUA 5B01A 4NUAA 2E8XA 4OKZA 2ZCOA 4XQTF 1YYTA 1HM4A 3BNXA 2Z4XA 3G4FA 1VG6A 3ZCDA 2Q80A 4H5EF 4GP1A 3P8LA 3OYRA 3KRAB 2F89F 1UBVA 3M01A 1WKZA 4L2XF 1KIZA 2P1CA 1KIYA 3EGTA 1JFAA 2ZEUA 4F6VA 4NKFA 4LTVA 3EZ3A 5AYPA 5KSXF 2E91A 5HN8A 3PYAA 3RYEA 3TFNA 3S9VA 4KFAA 5AFXA 1UBXA 4EA0A 3M00A 3NF2A 3LGZB 1YYSA 5IKHA 4WK5A 5ILJA 1N24A 3LG5A 1WL2A 3EFQA 3KROB 4OMHA 3V1VA 5CG6A 4KVDA 3ADZA 4LLSA 3N0FA 3V66A 3WCGA 1ZW5A 1N23A 2Q9ZA 1RQIA 3LK5A 3WCDA 2AZLA 3WCBA 1WL0A 3ICZA 5B0LA 3WJNA 5EATA 1V4IA 3VJ9A 4JYXA 2E4OA 4PVXF 5ILDA 3WC9A 5JV0F 1N21A 3TC1A 2AETA 2E90A 2J1OA 3IBAA 3VJEA 1WL1A 5JV1F 3M02A 4FP4A 3SDUA 5A0IA 1DGPA 2F94F 5DJRF 5IN8A 4EA1A 3WCLA 5B03A 2Q9YA 4H5DF 3AQCB 3WCAA 3AQBB 2E8TA 3KRFB 4LA5A 2ZY1A 5DHIA 3ACYA 3OACA 2E8UA 2Z4WA 3PH7A 4DI5A 4KK2A 5H9DA 4E9ZA 4XQRF 1RQJA 4KPJA 5HN7A 2Z4VA 3OABB 1HXGA 3KRCA 3V1XA 4GA3A 3WSAA 4JXNA 3RYWA 5B0IA 3DYHA 5DJPF 5JV2F 5DGMF 3N3LF 3NPKA 3WCCA 5DW7A 2AEKA 5ER8A 4NFJF 3SDQA 4KWDA 5A0JA 4LFEA 5ERMA 4GAXA 2Q58A 1RTRA 3NRIA 1HXCA 3DYGA 4NKEA 1V4KA 4F62A 5ILZA 3SAEA 1VG3A 1YV5A 3N45F 5IL3A 1V4HA 4P0VA 4KVYA 2RAHA 4HD1A 1UBYA 3KB9A 4KPDA 2Z52A 3N46F 2Z78A 2ZCQA 1YYRA 5DGNF 5IMNA 3Q2QA 4KVWA 5ILIA 4NG6A 4RXEA 4N9UA 2OPNA 4E1EA 3UCAA 3G4DA 5ERNA 1YHMA 3ACWA 3B7LA 3LVSA 3P5RA 5HNAA 2F8CF 5E8HA 1UBWA 1V4EA 3P41A 2Z50A 4RXDA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5AEL A;  3ASX A;  2FOR A;  4E9U A;  3PYB A;  4N1Z F;  5JUZ F;  3WEF A;  4QPF A;  4LPG F;  3WCJ A;  4KQ5 A;  3LMD A;  3WCI A;  5IKA A;  4LPH F;  3WSB A;  4Q23 A;  4MC3 A;  4OMG A;  3AQ0 A;  5IK6 A;  5DGS F;  3VJD A;  4MC8 A;  3ZMC A;  2PS5 A;  3LGK A;  3PDE A;  4LLT A;  3WCE A;  3Q1O A;  3VJ8 A;  1YQ7 A;  1YHL A;  2ZCR A;  5B02 A;  3LOM A;  2PS8 A;  3MAV A;  3NPR A;  3QKC A;  5IK0 A;  3CC9 A;  3KRP A;  3TFV A;  2Z7I A;  3APZ A;  3WEH A;  2E92 A;  4MC0 A;  4DZW A;  4F6X A;  3WCF A;  1HX9 A;  1YJ4 A;  3SDR A;  2E94 A;  2J5C A;  2ZCS A;  3WJK A;  1YHK A;  4JXY A;  2AEL A;  3M9U A;  3OAC B;  2FTZ A;  3PKO A;  3ID0 A;  4KVI A;  3ICN A;  4DXJ A;  2F8Z F;  5DJV F;  3KRC B;  2DH4 A;  3CKE A;  1WY0 A;  4RXC A;  2E93 A;  1VG4 A;  4UMJ A;  1HM7 A;  3N5J F;  5DZ2 A;  3ICM A;  1N22 A;  4GP2 A;  5E8K A;  3RBM A;  3N6K F;  4EA2 A;  4QXS F;  2ONG A;  3QQV A;  4LZ0 A;  5IL8 A;  5EAU A;  3TFP A;  3ZL6 A;  5B0K A;  4DHD A;  5E8L A;  1V4J A;  5DIQ F;  4LZ3 A;  1N1Z A;  5EAS A;  3KBK A;  2O1O A;  3LSN A;  2AZJ A;  2QIS A;  2Z4Z A;  5B0M A;  3VJC A;  4OKM A;  3N1V F;  4LA6 A;  5ILH A;  4RYP A;  1EZF A;  1N20 A;  3KRA A;  3WEJ A;  1YYU A;  2J1P A;  3N5H F;  3LJI A;  4JVJ F;  1JFG A;  2OGD A;  4P0W A;  4LTZ A;  2ZEV A;  3Q30 A;  3BNY A;  2OPM A;  2H8O A;  2E8W A;  1WMW A;  5B0J A;  1FPS A;  5JA0 F;  3ACX A;  3ZOU A;  2EWG A;  4FJQ A;  4JZX A;  4K10 A;  2E8V A;  5IVG A;  5IMP A;  5IK9 A;  5ERO A;  3VJA A;  3TS7 A;  3Q2Z A;  4JZB A;  4RXA A;  2PS4 A;  4PVY F;  5B00 A;  4XQS F;  5A0K A;  3N49 F;  2Z4Y A;  3LLW A;  4DWB A;  1VG7 A;  3RMG A;  3N0G A;  3P8R A;  3WE9 A;  4NFI F;  3ZMB A;  3MZV A;  3SDT A;  1DI1 A;  3M0G A;  3LEE A;  1WL3 A;  3KRO A;  2OA6 A;  5ILK A;  3DYF A;  4LUU A;  3LDW A;  2E95 A;  3ICK A;  2ONH A;  5I1U A;  1N1B A;  5IM1 A;  3P5P A;  2Z7H A;  4DWG A;  3W7F A;  5C05 A;  3IPI A;  4LZC A;  1VG2 A;  2PS6 A;  3AE0 A;  3S4J A;  3KRP B;  4NFK F;  1YYQ A;  4LXW A;  3WEK A;  4P0X A;  3WJO A;  3WCM A;  4LOB A;  4LFG A;  3N1W F;  4DEM F;  5DHK A;  3WEG A;  5AHU B;  3VJB A;  4LFV F;  3CP6 A;  4OGU A;  4ZQ8 A;  2VF6 A;  4LIX A;  1PS1 A;  2AZK A;  3SDV A;  3KRF A;  2F9K F;  4KUX A;  5CG5 A;  2PS7 A;  4H5C F;  3WCH A;  1HXA A;  2F92 F;  3N3D A;  3OAB A;  5HN9 A;  5ILY A;  2I19 A;  4KKM A;  3WEI A;  2F7M F;  3LZ9 A;  4KQS A;  5IMI A;  4RNQ A;  4KQU A;  5B01 A;  4NUA A;  2E8X A;  4OKZ A;  2ZCO A;  4XQT F;  1YYT A;  1HM4 A;  3BNX A;  2Z4X A;  3G4F A;  1VG6 A;  3ZCD A;  2Q80 A;  4H5E F;  4GP1 A;  3P8L A;  3OYR A;  3KRA B;  2F89 F;  1UBV A;  3M01 A;  1WKZ A;  4L2X F;  1KIZ A;  2P1C A;  1KIY A;  3EGT A;  1JFA A;  2ZEU A;  4F6V A;  4NKF A;  4LTV A;  3EZ3 A;  5AYP A;  5KSX F;  2E91 A;  5HN8 A;  3PYA A;  3RYE A;  3TFN A;  3S9V A;  4KFA A;  5AFX A;  1UBX A;  4EA0 A;  3M00 A;  3NF2 A;  3LGZ B;  1YYS A;  5IKH A;  4WK5 A;  5ILJ A;  1N24 A;  3LG5 A;  1WL2 A;  3EFQ A;  3KRO B;  4OMH A;  3V1V A;  5CG6 A;  4KVD A;  3ADZ A;  4LLS A;  3N0F A;  3V66 A;  3WCG A;  1ZW5 A;  1N23 A;  2Q9Z A;  1RQI A;  3LK5 A;  3WCD A;  2AZL A;  3WCB A;  1WL0 A;  3ICZ A;  5B0L A;  3WJN A;  5EAT A;  1V4I A;  3VJ9 A;  4JYX A;  2E4O A;  4PVX F;  5ILD A;  3WC9 A;  5JV0 F;  1N21 A;  3TC1 A;  2AET A;  2E90 A;  2J1O A;  3IBA A;  3VJE A;  1WL1 A;  5JV1 F;  3M02 A;  4FP4 A;  3SDU A;  5A0I A;  1DGP A;  2F94 F;  5DJR F;  5IN8 A;  4EA1 A;  3WCL A;  5B03 A;  2Q9Y A;  4H5D F;  3AQC B;  3WCA A;  3AQB B;  2E8T A;  3KRF B;  4LA5 A;  2ZY1 A;  5DHI A;  3ACY A;  3OAC A;  2E8U A;  2Z4W A;  3PH7 A;  4DI5 A;  4KK2 A;  5H9D A;  4E9Z A;  4XQR F;  1RQJ A;  4KPJ A;  5HN7 A;  2Z4V A;  3OAB B;  1HXG A;  3KRC A;  3V1X A;  4GA3 A;  3WSA A;  4JXN A;  3RYW A;  5B0I A;  3DYH A;  5DJP F;  5JV2 F;  5DGM F;  3N3L F;  3NPK A;  3WCC A;  5DW7 A;  2AEK A;  5ER8 A;  4NFJ F;  3SDQ A;  4KWD A;  5A0J A;  4LFE A;  5ERM A;  4GAX A;  2Q58 A;  1RTR A;  3NRI A;  1HXC A;  3DYG A;  4NKE A;  1V4K A;  4F62 A;  5ILZ A;  3SAE A;  1VG3 A;  1YV5 A;  3N45 F;  5IL3 A;  1V4H A;  4P0V A;  4KVY A;  2RAH A;  4HD1 A;  1UBY A;  3KB9 A;  4KPD A;  2Z52 A;  3N46 F;  2Z78 A;  2ZCQ A;  1YYR A;  5DGN F;  5IMN A;  3Q2Q A;  4KVW A;  5ILI A;  4NG6 A;  4RXE A;  4N9U A;  2OPN A;  4E1E A;  3UCA A;  3G4D A;  5ERN A;  1YHM A;  3ACW A;  3B7L A;  3LVS A;  3P5R A;  5HNA A;  2F8C F;  5E8H A;  1UBW A;  1V4E A;  3P41 A;  2Z50 A;  4RXD A; 
#chains in the Genus database with same CATH topology
 5AEL A;  3ASX A;  2FOR A;  4E9U A;  3PYB A;  4N1Z F;  5JUZ F;  3WEF A;  4QPF A;  4LPG F;  3WCJ A;  4KQ5 A;  3LMD A;  3WCI A;  5IKA A;  4LPH F;  3WSB A;  4Q23 A;  4MC3 A;  4OMG A;  3AQ0 A;  5IK6 A;  5DGS F;  3VJD A;  4MC8 A;  3ZMC A;  2PS5 A;  3LGK A;  3PDE A;  4LLT A;  3WCE A;  3Q1O A;  3VJ8 A;  1YQ7 A;  1YHL A;  2ZCR A;  5B02 A;  3LOM A;  2PS8 A;  3MAV A;  3NPR A;  3QKC A;  5IK0 A;  3CC9 A;  3KRP A;  3TFV A;  2Z7I A;  3APZ A;  3WEH A;  2E92 A;  4MC0 A;  4DZW A;  4F6X A;  3WCF A;  1HX9 A;  1YJ4 A;  3SDR A;  2E94 A;  2J5C A;  2ZCS A;  3WJK A;  1YHK A;  4JXY A;  2AEL A;  3M9U A;  3OAC B;  2FTZ A;  3PKO A;  3ID0 A;  4KVI A;  3ICN A;  4DXJ A;  2F8Z F;  5DJV F;  3KRC B;  2DH4 A;  3CKE A;  1WY0 A;  4RXC A;  2E93 A;  1VG4 A;  4UMJ A;  1HM7 A;  3N5J F;  5DZ2 A;  3ICM A;  1N22 A;  4GP2 A;  5E8K A;  3RBM A;  3N6K F;  4EA2 A;  4QXS F;  2ONG A;  3QQV A;  4LZ0 A;  5IL8 A;  5EAU A;  3TFP A;  3ZL6 A;  5B0K A;  4DHD A;  5E8L A;  1V4J A;  5DIQ F;  4LZ3 A;  1N1Z A;  5EAS A;  3KBK A;  2O1O A;  3LSN A;  2AZJ A;  2QIS A;  2Z4Z A;  5B0M A;  3VJC A;  4OKM A;  3N1V F;  4LA6 A;  5ILH A;  4RYP A;  1EZF A;  1N20 A;  3KRA A;  3WEJ A;  1YYU A;  2J1P A;  3N5H F;  3LJI A;  4JVJ F;  1JFG A;  2OGD A;  4P0W A;  4LTZ A;  2ZEV A;  3Q30 A;  3BNY A;  2OPM A;  2H8O A;  2E8W A;  1WMW A;  5B0J A;  1FPS A;  5JA0 F;  3ACX A;  3ZOU A;  2EWG A;  4FJQ A;  4JZX A;  4K10 A;  2E8V A;  5IVG A;  5IMP A;  5IK9 A;  5ERO A;  3VJA A;  3TS7 A;  3Q2Z A;  4JZB A;  4RXA A;  2PS4 A;  4PVY F;  5B00 A;  4XQS F;  5A0K A;  3N49 F;  2Z4Y A;  3LLW A;  4DWB A;  1VG7 A;  3RMG A;  3N0G A;  3P8R A;  3WE9 A;  4NFI F;  3ZMB A;  3MZV A;  3SDT A;  1DI1 A;  3M0G A;  3LEE A;  1WL3 A;  3KRO A;  2OA6 A;  5ILK A;  3DYF A;  4LUU A;  3LDW A;  2E95 A;  3ICK A;  2ONH A;  5I1U A;  1N1B A;  5IM1 A;  3P5P A;  2Z7H A;  4DWG A;  3W7F A;  5C05 A;  3IPI A;  4LZC A;  1VG2 A;  2PS6 A;  3AE0 A;  3S4J A;  3KRP B;  4NFK F;  1YYQ A;  4LXW A;  3WEK A;  4P0X A;  3WJO A;  3WCM A;  4LOB A;  4LFG A;  3N1W F;  4DEM F;  5DHK A;  3WEG A;  5AHU B;  3VJB A;  4LFV F;  3CP6 A;  4OGU A;  4ZQ8 A;  2VF6 A;  4LIX A;  1PS1 A;  2AZK A;  3SDV A;  3KRF A;  2F9K F;  4KUX A;  5CG5 A;  2PS7 A;  4H5C F;  3WCH A;  1HXA A;  2F92 F;  3N3D A;  3OAB A;  5HN9 A;  5ILY A;  2I19 A;  4KKM A;  3WEI A;  2F7M F;  3LZ9 A;  4KQS A;  5IMI A;  4RNQ A;  4KQU A;  5B01 A;  4NUA A;  2E8X A;  4OKZ A;  2ZCO A;  4XQT F;  1YYT A;  1HM4 A;  3BNX A;  2Z4X A;  3G4F A;  1VG6 A;  3ZCD A;  2Q80 A;  4H5E F;  4GP1 A;  3P8L A;  3OYR A;  3KRA B;  2F89 F;  1UBV A;  3M01 A;  1WKZ A;  4L2X F;  1KIZ A;  2P1C A;  1KIY A;  3EGT A;  1JFA A;  2ZEU A;  4F6V A;  4NKF A;  4LTV A;  3EZ3 A;  5AYP A;  5KSX F;  2E91 A;  5HN8 A;  3PYA A;  3RYE A;  3TFN A;  3S9V A;  4KFA A;  5AFX A;  1UBX A;  4EA0 A;  3M00 A;  3NF2 A;  3LGZ B;  1YYS A;  5IKH A;  4WK5 A;  5ILJ A;  1N24 A;  3LG5 A;  1WL2 A;  3EFQ A;  3KRO B;  4OMH A;  3V1V A;  5CG6 A;  4KVD A;  3ADZ A;  4LLS A;  3N0F A;  3V66 A;  3WCG A;  1ZW5 A;  1N23 A;  2Q9Z A;  1RQI A;  3LK5 A;  3WCD A;  2AZL A;  3WCB A;  1WL0 A;  3ICZ A;  5B0L A;  3WJN A;  5EAT A;  1V4I A;  3VJ9 A;  4JYX A;  2E4O A;  4PVX F;  5ILD A;  3WC9 A;  5JV0 F;  1N21 A;  3TC1 A;  2AET A;  2E90 A;  2J1O A;  3IBA A;  3VJE A;  1WL1 A;  5JV1 F;  3M02 A;  4FP4 A;  3SDU A;  5A0I A;  1DGP A;  2F94 F;  5DJR F;  5IN8 A;  4EA1 A;  3WCL A;  5B03 A;  2Q9Y A;  4H5D F;  3AQC B;  3WCA A;  3AQB B;  2E8T A;  3KRF B;  4LA5 A;  2ZY1 A;  5DHI A;  3ACY A;  3OAC A;  2E8U A;  2Z4W A;  3PH7 A;  4DI5 A;  4KK2 A;  5H9D A;  4E9Z A;  4XQR F;  1RQJ A;  4KPJ A;  5HN7 A;  2Z4V A;  3OAB B;  1HXG A;  3KRC A;  3V1X A;  4GA3 A;  3WSA A;  4JXN A;  3RYW A;  5B0I A;  3DYH A;  5DJP F;  5JV2 F;  5DGM F;  3N3L F;  3NPK A;  3WCC A;  5DW7 A;  2AEK A;  5ER8 A;  4NFJ F;  3SDQ A;  4KWD A;  5A0J A;  4LFE A;  5ERM A;  4GAX A;  2Q58 A;  1RTR A;  3NRI A;  1HXC A;  3DYG A;  4NKE A;  1V4K A;  4F62 A;  5ILZ A;  3SAE A;  1VG3 A;  1YV5 A;  3N45 F;  5IL3 A;  1V4H A;  4P0V A;  4KVY A;  2RAH A;  4HD1 A;  1UBY A;  3KB9 A;  4KPD A;  2Z52 A;  3N46 F;  2Z78 A;  2ZCQ A;  1YYR A;  5DGN F;  5IMN A;  3Q2Q A;  4KVW A;  5ILI A;  4NG6 A;  4RXE A;  4N9U A;  2OPN A;  4E1E A;  3UCA A;  3G4D A;  5ERN A;  1YHM A;  3ACW A;  3B7L A;  3LVS A;  3P5R A;  5HNA A;  2F8C F;  5E8H A;  1UBW A;  1V4E A;  3P41 A;  2Z50 A;  4RXD A; 
#chains in the Genus database with same CATH homology
 5AEL A;  3ASX A;  2FOR A;  4E9U A;  3PYB A;  4N1Z F;  5JUZ F;  3WEF A;  4QPF A;  4LPG F;  3WCJ A;  4KQ5 A;  3LMD A;  3WCI A;  5IKA A;  4LPH F;  3WSB A;  4Q23 A;  4MC3 A;  4OMG A;  3AQ0 A;  5IK6 A;  5DGS F;  3VJD A;  4MC8 A;  3ZMC A;  2PS5 A;  3LGK A;  3PDE A;  4LLT A;  3WCE A;  3Q1O A;  3VJ8 A;  1YQ7 A;  1YHL A;  2ZCR A;  5B02 A;  3LOM A;  2PS8 A;  3MAV A;  3NPR A;  3QKC A;  5IK0 A;  3CC9 A;  3KRP A;  3TFV A;  2Z7I A;  3APZ A;  3WEH A;  2E92 A;  4MC0 A;  4DZW A;  4F6X A;  3WCF A;  1HX9 A;  1YJ4 A;  3SDR A;  2E94 A;  2J5C A;  2ZCS A;  3WJK A;  1YHK A;  4JXY A;  2AEL A;  3M9U A;  3OAC B;  2FTZ A;  3PKO A;  3ID0 A;  4KVI A;  3ICN A;  4DXJ A;  2F8Z F;  5DJV F;  3KRC B;  2DH4 A;  3CKE A;  1WY0 A;  4RXC A;  2E93 A;  1VG4 A;  4UMJ A;  1HM7 A;  3N5J F;  5DZ2 A;  3ICM A;  1N22 A;  4GP2 A;  5E8K A;  3RBM A;  3N6K F;  4EA2 A;  4QXS F;  2ONG A;  3QQV A;  4LZ0 A;  5IL8 A;  5EAU A;  3TFP A;  3ZL6 A;  5B0K A;  4DHD A;  5E8L A;  1V4J A;  5DIQ F;  4LZ3 A;  1N1Z A;  5EAS A;  3KBK A;  2O1O A;  3LSN A;  2AZJ A;  2QIS A;  2Z4Z A;  5B0M A;  3VJC A;  4OKM A;  3N1V F;  4LA6 A;  5ILH A;  4RYP A;  1EZF A;  1N20 A;  3KRA A;  3WEJ A;  1YYU A;  2J1P A;  3N5H F;  3LJI A;  4JVJ F;  1JFG A;  2OGD A;  4P0W A;  4LTZ A;  2ZEV A;  3Q30 A;  3BNY A;  2OPM A;  2H8O A;  2E8W A;  1WMW A;  5B0J A;  1FPS A;  5JA0 F;  3ACX A;  3ZOU A;  2EWG A;  4FJQ A;  4JZX A;  4K10 A;  2E8V A;  5IVG A;  5IMP A;  5IK9 A;  5ERO A;  3VJA A;  3TS7 A;  3Q2Z A;  4JZB A;  4RXA A;  2PS4 A;  4PVY F;  5B00 A;  4XQS F;  5A0K A;  3N49 F;  2Z4Y A;  3LLW A;  4DWB A;  1VG7 A;  3RMG A;  3N0G A;  3P8R A;  3WE9 A;  4NFI F;  3ZMB A;  3MZV A;  3SDT A;  1DI1 A;  3M0G A;  3LEE A;  1WL3 A;  3KRO A;  2OA6 A;  5ILK A;  3DYF A;  4LUU A;  3LDW A;  2E95 A;  3ICK A;  2ONH A;  5I1U A;  1N1B A;  5IM1 A;  3P5P A;  2Z7H A;  4DWG A;  3W7F A;  5C05 A;  3IPI A;  4LZC A;  1VG2 A;  2PS6 A;  3AE0 A;  3S4J A;  3KRP B;  4NFK F;  1YYQ A;  4LXW A;  3WEK A;  4P0X A;  3WJO A;  3WCM A;  4LOB A;  4LFG A;  3N1W F;  4DEM F;  5DHK A;  3WEG A;  5AHU B;  3VJB A;  4LFV F;  3CP6 A;  4OGU A;  4ZQ8 A;  2VF6 A;  4LIX A;  1PS1 A;  2AZK A;  3SDV A;  3KRF A;  2F9K F;  4KUX A;  5CG5 A;  2PS7 A;  4H5C F;  3WCH A;  1HXA A;  2F92 F;  3N3D A;  3OAB A;  5HN9 A;  5ILY A;  2I19 A;  4KKM A;  3WEI A;  2F7M F;  3LZ9 A;  4KQS A;  5IMI A;  4RNQ A;  4KQU A;  5B01 A;  4NUA A;  2E8X A;  4OKZ A;  2ZCO A;  4XQT F;  1YYT A;  1HM4 A;  3BNX A;  2Z4X A;  3G4F A;  1VG6 A;  3ZCD A;  2Q80 A;  4H5E F;  4GP1 A;  3P8L A;  3OYR A;  3KRA B;  2F89 F;  1UBV A;  3M01 A;  1WKZ A;  4L2X F;  1KIZ A;  2P1C A;  1KIY A;  3EGT A;  1JFA A;  2ZEU A;  4F6V A;  4NKF A;  4LTV A;  3EZ3 A;  5AYP A;  5KSX F;  2E91 A;  5HN8 A;  3PYA A;  3RYE A;  3TFN A;  3S9V A;  4KFA A;  5AFX A;  1UBX A;  4EA0 A;  3M00 A;  3NF2 A;  3LGZ B;  1YYS A;  5IKH A;  4WK5 A;  5ILJ A;  1N24 A;  3LG5 A;  1WL2 A;  3EFQ A;  3KRO B;  4OMH A;  3V1V A;  5CG6 A;  4KVD A;  3ADZ A;  4LLS A;  3N0F A;  3V66 A;  3WCG A;  1ZW5 A;  1N23 A;  2Q9Z A;  1RQI A;  3LK5 A;  3WCD A;  2AZL A;  3WCB A;  1WL0 A;  3ICZ A;  5B0L A;  3WJN A;  5EAT A;  1V4I A;  3VJ9 A;  4JYX A;  2E4O A;  4PVX F;  5ILD A;  3WC9 A;  5JV0 F;  1N21 A;  3TC1 A;  2AET A;  2E90 A;  2J1O A;  3IBA A;  3VJE A;  1WL1 A;  5JV1 F;  3M02 A;  4FP4 A;  3SDU A;  5A0I A;  1DGP A;  2F94 F;  5DJR F;  5IN8 A;  4EA1 A;  3WCL A;  5B03 A;  2Q9Y A;  4H5D F;  3AQC B;  3WCA A;  3AQB B;  2E8T A;  3KRF B;  4LA5 A;  2ZY1 A;  5DHI A;  3ACY A;  3OAC A;  2E8U A;  2Z4W A;  3PH7 A;  4DI5 A;  4KK2 A;  5H9D A;  4E9Z A;  4XQR F;  1RQJ A;  4KPJ A;  5HN7 A;  2Z4V A;  3OAB B;  1HXG A;  3KRC A;  3V1X A;  4GA3 A;  3WSA A;  4JXN A;  3RYW A;  5B0I A;  3DYH A;  5DJP F;  5JV2 F;  5DGM F;  3N3L F;  3NPK A;  3WCC A;  5DW7 A;  2AEK A;  5ER8 A;  4NFJ F;  3SDQ A;  4KWD A;  5A0J A;  4LFE A;  5ERM A;  4GAX A;  2Q58 A;  1RTR A;  3NRI A;  1HXC A;  3DYG A;  4NKE A;  1V4K A;  4F62 A;  5ILZ A;  3SAE A;  1VG3 A;  1YV5 A;  3N45 F;  5IL3 A;  1V4H A;  4P0V A;  4KVY A;  2RAH A;  4HD1 A;  1UBY A;  3KB9 A;  4KPD A;  2Z52 A;  3N46 F;  2Z78 A;  2ZCQ A;  1YYR A;  5DGN F;  5IMN A;  3Q2Q A;  4KVW A;  5ILI A;  4NG6 A;  4RXE A;  4N9U A;  2OPN A;  4E1E A;  3UCA A;  3G4D A;  5ERN A;  1YHM A;  3ACW A;  3B7L A;  3LVS A;  3P5R A;  5HNA A;  2F8C F;  5E8H A;  1UBW A;  1V4E A;  3P41 A;  2Z50 A;  4RXD A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...