4DZWA

Crystal structure of trypanosome cruzi farnesyl diphosphate synthase in complex with [2-(cyclohexylamino)ethane-1,1-diyl]bisphosphonic acid and mg2+
Total Genus 138
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
138
sequence length
359
structure length
359
Chain Sequence
ASMERFLSVYDEVQAFLLDQLQSKYEIDPNRARYLRIMMDTTCLGGKYFRGMTVVNVAEGFLAVTQHDEATKERILHDACVGGWMIEFLQAHYLVEDDIMDGSVMRRGKPCWYRFPGVTTQCAINDGIILKSWTQIMAWHYFADRPFLKDLLCLFQKVDYATAVGQMYDVTSMCDSNKLDPEVAQPMTTDFAEFTPAIYKRIVKYKTTFYTYLLPLVMGLFVSEAAASVEMNLVERVAHLIGEYFQVQDDVMDCFTPPEQLGKVGTDIEDAKCSWLAVTFLGKANAAQVAEFKANYGDKDPAKVAVVKRLYSEANLQADFAAYEAEVVREVESLIEQLKVKSPTFAESVAVVWEKTHKR
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Transferase/transferase inhibitor
molecule keywords Farnesyl pyrophosphate synthase
publication title Design, synthesis, calorimetry, and crystallographic analysis of 2-alkylaminoethyl-1,1-bisphosphonates as inhibitors of Trypanosoma cruzi farnesyl diphosphate synthase.
pubmed doi rcsb
source organism Trypanosoma cruzi
total genus 138
structure length 359
sequence length 359
ec nomenclature ec 2.5.1.10: (2E,6E)-farnesyl diphosphate synthase.
pdb deposition date 2012-03-01

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00348 polyprenyl_synt Polyprenyl synthetase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.600.10 Mainly Alpha Orthogonal Bundle Farnesyl Diphosphate Synthase Farnesyl Diphosphate Synthase 4dzwA00
5E8KA 3N3LF 4RYPA 3BNYA 2Z4ZA 3M01A 3P41A 5AELA 1RTRA 3SDTA 4KPJA 4PVXF 1YYUA 4GP2A 2QISA 1UBYA 3WCJA 3WSAA 3V1VA 2VF6A 4NFIF 2ONGA 3IBAA 5IK0A 1ZW5A 1WL2A 4LZCA 2DH4A 2Z50A 3APZA 3WJOA 3ACWA 5ILIA 5H9DA 2E8TA 2AETA 3W7FA 1N24A 2P1CA 5IMNA 3N5JF 5CG6A 3SDRA 2RAHA 5EAUA 5EASA 1UBVA 3P8RA 3DYGA 4KK2A 5DGMF 4LA6A 3SDVA 3SAEA 4EA2A 4EA0A 2E4OA 5HN8A 4XQTF 3QKCA 3S4JA 5HNAA 5ILKA 4N1ZF 5DGSF 2E94A 2Z4XA 3NF2A 2ZY1A 1WL0A 1YYQA 3OACA 4FP4A 3ACYA 3WEIA 5JV0F 4LXWA 4DHDA 2AZKA 2F94F 2J5CA 4NUAA 2F8ZF 3LVSA 3WJKA 5EROA 3OACB 1JFAA 4LFEA 5DHIA 2E8WA 5ILDA 3WCCA 4RXDA 3LK5A 5IN8A 4LPGF 3N6KF 1N21A 3WCHA 3M9UA 1WMWA 4WK5A 4EA1A 3RMGA 1N1ZA 1N1BA 1PS1A 4KKMA 3VJDA 3M02A 4GP1A 5IKAA 4H5DF 2E8UA 3V1XA 5EATA 3S9VA 3QQVA 5ERMA 2ZEUA 4P0VA 3WEGA 5C05A 2E8XA 3CKEA 4OGUA 3BNXA 4KVIA 2Z4YA 3LSNA 5IVGA 3RBMA 3VJCA 5IL3A 5HN9A 2AEKA 5IK9A 3RYEA 4K10A 2E8VA 3KBKA 1VG6A 5ILYA 3ADZA 4XQSF 4JXNA 1YHKA 1N20A 4LA5A 2AELA 3EZ3A 4LZ0A 1HXGA 4LTVA 5ILHA 4DEMF 4KPDA 3LOMA 3Q2ZA 3KRPA 5B0MA 1VG4A 2Q9YA 5B0IA 2E91A 5DJVF 4E9ZA 3KRPB 4L2XF 1DGPA 5B01A 5JA0F 1N23A 3VJ8A 4KQ5A 5B00A 3AQ0A 3TC1A 3TFNA 3WEHA 2Z7IA 5ERNA 2F7MF 3N5HF 4JZXA 4PVYF 3N1WF 1YHLA 1VG7A 2PS7A 4LLTA 3KRFA 3LGKA 5JV2F 3ZMBA 4DXJA 3N46F 2Z7HA 5DJRF 3KROA 3N45F 4XQRF 1V4HA 3AQBB 3KRFB 3P5RA 4KQSA 1FPSA 5ER8A 5IKHA 5A0KA 3ASXA 2I19A 3KROB 3M0GA 4KQUA 4NKEA 1UBWA 3ICZA 4E1EA 5I1UA 3TFPA 3KRAA 2ZCOA 3MZVA 3N0FA 2Q80A 1HM4A 3UCAA 4KVDA 2AZJA 4RXAA 3WEKA 4OKMA 2FTZA 3KRAB 2E93A 3PDEA 1WL3A 1YYSA 4JZBA 4NFJF 1EZFA 4MC0A 4LLSA 2FORA 5AYPA 1YV5A 4LFGA 4DWGA 3DYFA 5DHKA 1HXAA 3SDQA 3ZOUA 3IPIA 3WCMA 3Q1OA 4GAXA 5ILJA 3V66A 5DZ2A 1V4IA 3KRCA 4QXSF 4LUUA 4LTZA 1WKZA 1YHMA 5AHUB 3P8LA 2Q9ZA 3KB9A 3ACXA 3KRCB 3LLWA 5HN7A 5IMPA 3VJ9A 3ICMA 4KVWA 2OPMA 5KSXF 3WSBA 4NG6A 4NFKF 5B02A 1HM7A 3G4FA 3AE0A 4F6XA 1YYTA 3PKOA 4RXEA 1DI1A 3NPKA 3MAVA 4HD1A 4P0WA 3G4DA 5DJPF 1HXCA 2PS5A 2ZCQA 3OYRA 3EGTA 4LPHF 4MC3A 4KUXA 3OABA 1YQ7A 4JXYA 2F89F 3WCEA 5ILZA 3SDUA 4MC8A 5IL8A 4LZ3A 4GA3A 3LEEA 3OABB 3PYAA 4OKZA 4Q23A 2PS4A 3P5PA 4JVJF 2OA6A 3LG5A 3RYWA 4LIXA 1HX9A 4DI5A 1V4KA 2F8CF 2EWGA 3WCIA 2OPNA 3ZMCA 1VG3A 1YYRA 3B7LA 4UMJA 2E95A 1RQIA 5E8HA 1KIZA 3LZ9A 1WY0A 5B0KA 5DIQF 2Z4WA 1N22A 3ICNA 4RNQA 3N3DA 5B0JA 5DGNF 3PYBA 1JFGA 3ICKA 3LJIA 5DW7A 3ID0A 4N9UA 3LGZB 5IK6A 4QPFA 2O1OA 1WL1A 3ZL6A 2Z52A 2ZCRA 1KIYA 3NPRA 5A0IA 2AZLA 4FJQA 3TS7A 3WCFA 4OMGA 2J1OA 3M00A 4H5CF 3PH7A 3VJEA 3N0GA 3Q2QA 3N1VF 2E92A 4JYXA 2ZCSA 4KVYA 2Z4VA 3WEFA 2Q58A 2PS6A 3WCDA 4KWDA 4LFVF 4F6VA 5IM1A 3LDWA 3WC9A 3N49F 2Z78A 3WEJA 3AQCB 5E8LA 4DWBA 1RQJA 2OGDA 5AFXA 5B0LA 4P0XA 3DYHA 2H8OA 2J1PA 3WJNA 4DZWA 2PS8A 3CC9A 1VG2A 3WCGA 3CP6A 1V4EA 3TFVA 4RXCA 4E9UA 3LMDA 5B03A 3NRIA 1UBXA 3WCLA 2E90A 2F9KF 2ZEVA 4OMHA 3VJBA 4F62A 5IMIA 3ZCDA 4H5EF 1V4JA 1YJ4A 4KFAA 3VJAA 3EFQA 3Q30A 2ONHA 5JUZF 5A0JA 2F92F 4NKFA 5CG5A 5JV1F 3WCAA 4LOBA 3WE9A 3WCBA 4ZQ8A
chains in the Genus database with same CATH superfamily
5E8KA 3N3LF 4RYPA 3BNYA 2Z4ZA 3M01A 3P41A 5AELA 1RTRA 3SDTA 4KPJA 4PVXF 1YYUA 4GP2A 2QISA 1UBYA 3WCJA 3WSAA 3V1VA 2VF6A 4NFIF 2ONGA 3IBAA 5IK0A 1ZW5A 1WL2A 4LZCA 2DH4A 2Z50A 3APZA 3WJOA 3ACWA 5ILIA 5H9DA 2E8TA 2AETA 3W7FA 1N24A 2P1CA 5IMNA 3N5JF 5CG6A 3SDRA 2RAHA 5EAUA 5EASA 1UBVA 3P8RA 3DYGA 4KK2A 5DGMF 4LA6A 3SDVA 3SAEA 4EA2A 4EA0A 2E4OA 5HN8A 4XQTF 3QKCA 3S4JA 5HNAA 5ILKA 4N1ZF 5DGSF 2E94A 2Z4XA 3NF2A 2ZY1A 1WL0A 1YYQA 3OACA 4FP4A 3ACYA 3WEIA 5JV0F 4LXWA 4DHDA 2AZKA 2F94F 2J5CA 4NUAA 2F8ZF 3LVSA 3WJKA 5EROA 3OACB 1JFAA 4LFEA 5DHIA 2E8WA 5ILDA 3WCCA 4RXDA 3LK5A 5IN8A 4LPGF 3N6KF 1N21A 3WCHA 3M9UA 1WMWA 4WK5A 4EA1A 3RMGA 1N1ZA 1N1BA 1PS1A 4KKMA 3VJDA 3M02A 4GP1A 5IKAA 4H5DF 2E8UA 3V1XA 5EATA 3S9VA 3QQVA 5ERMA 2ZEUA 4P0VA 3WEGA 5C05A 2E8XA 3CKEA 4OGUA 3BNXA 4KVIA 2Z4YA 3LSNA 5IVGA 3RBMA 3VJCA 5IL3A 5HN9A 2AEKA 5IK9A 3RYEA 4K10A 2E8VA 3KBKA 1VG6A 5ILYA 3ADZA 4XQSF 4JXNA 1YHKA 1N20A 4LA5A 2AELA 3EZ3A 4LZ0A 1HXGA 4LTVA 5ILHA 4DEMF 4KPDA 3LOMA 3Q2ZA 3KRPA 5B0MA 1VG4A 2Q9YA 5B0IA 2E91A 5DJVF 4E9ZA 3KRPB 4L2XF 1DGPA 5B01A 5JA0F 1N23A 3VJ8A 4KQ5A 5B00A 3AQ0A 3TC1A 3TFNA 3WEHA 2Z7IA 5ERNA 2F7MF 3N5HF 4JZXA 4PVYF 3N1WF 1YHLA 1VG7A 2PS7A 4LLTA 3KRFA 3LGKA 5JV2F 3ZMBA 4DXJA 3N46F 2Z7HA 5DJRF 3KROA 3N45F 4XQRF 1V4HA 3AQBB 3KRFB 3P5RA 4KQSA 1FPSA 5ER8A 5IKHA 5A0KA 3ASXA 2I19A 3KROB 3M0GA 4KQUA 4NKEA 1UBWA 3ICZA 4E1EA 5I1UA 3TFPA 3KRAA 2ZCOA 3MZVA 3N0FA 2Q80A 1HM4A 3UCAA 4KVDA 2AZJA 4RXAA 3WEKA 4OKMA 2FTZA 3KRAB 2E93A 3PDEA 1WL3A 1YYSA 4JZBA 4NFJF 1EZFA 4MC0A 4LLSA 2FORA 5AYPA 1YV5A 4LFGA 4DWGA 3DYFA 5DHKA 1HXAA 3SDQA 3ZOUA 3IPIA 3WCMA 3Q1OA 4GAXA 5ILJA 3V66A 5DZ2A 1V4IA 3KRCA 4QXSF 4LUUA 4LTZA 1WKZA 1YHMA 5AHUB 3P8LA 2Q9ZA 3KB9A 3ACXA 3KRCB 3LLWA 5HN7A 5IMPA 3VJ9A 3ICMA 4KVWA 2OPMA 5KSXF 3WSBA 4NG6A 4NFKF 5B02A 1HM7A 3G4FA 3AE0A 4F6XA 1YYTA 3PKOA 4RXEA 1DI1A 3NPKA 3MAVA 4HD1A 4P0WA 3G4DA 5DJPF 1HXCA 2PS5A 2ZCQA 3OYRA 3EGTA 4LPHF 4MC3A 4KUXA 3OABA 1YQ7A 4JXYA 2F89F 3WCEA 5ILZA 3SDUA 4MC8A 5IL8A 4LZ3A 4GA3A 3LEEA 3OABB 3PYAA 4OKZA 4Q23A 2PS4A 3P5PA 4JVJF 2OA6A 3LG5A 3RYWA 4LIXA 1HX9A 4DI5A 1V4KA 2F8CF 2EWGA 3WCIA 2OPNA 3ZMCA 1VG3A 1YYRA 3B7LA 4UMJA 2E95A 1RQIA 5E8HA 1KIZA 3LZ9A 1WY0A 5B0KA 5DIQF 2Z4WA 1N22A 3ICNA 4RNQA 3N3DA 5B0JA 5DGNF 3PYBA 1JFGA 3ICKA 3LJIA 5DW7A 3ID0A 4N9UA 3LGZB 5IK6A 4QPFA 2O1OA 1WL1A 3ZL6A 2Z52A 2ZCRA 1KIYA 3NPRA 5A0IA 2AZLA 4FJQA 3TS7A 3WCFA 4OMGA 2J1OA 3M00A 4H5CF 3PH7A 3VJEA 3N0GA 3Q2QA 3N1VF 2E92A 4JYXA 2ZCSA 4KVYA 2Z4VA 3WEFA 2Q58A 2PS6A 3WCDA 4KWDA 4LFVF 4F6VA 5IM1A 3LDWA 3WC9A 3N49F 2Z78A 3WEJA 3AQCB 5E8LA 4DWBA 1RQJA 2OGDA 5AFXA 5B0LA 4P0XA 3DYHA 2H8OA 2J1PA 3WJNA 4DZWA 2PS8A 3CC9A 1VG2A 3WCGA 3CP6A 1V4EA 3TFVA 4RXCA 4E9UA 3LMDA 5B03A 3NRIA 1UBXA 3WCLA 2E90A 2F9KF 2ZEVA 4OMHA 3VJBA 4F62A 5IMIA 3ZCDA 4H5EF 1V4JA 1YJ4A 4KFAA 3VJAA 3EFQA 3Q30A 2ONHA 5JUZF 5A0JA 2F92F 4NKFA 5CG5A 5JV1F 3WCAA 4LOBA 3WE9A 3WCBA 4ZQ8A
chains in the Genus database with same CATH topology
5E8KA 3N3LF 4RYPA 3BNYA 2Z4ZA 3M01A 3P41A 5AELA 1RTRA 3SDTA 4KPJA 4PVXF 1YYUA 4GP2A 2QISA 1UBYA 3WCJA 3WSAA 3V1VA 2VF6A 4NFIF 2ONGA 3IBAA 5IK0A 1ZW5A 1WL2A 4LZCA 2DH4A 2Z50A 3APZA 3WJOA 3ACWA 5ILIA 5H9DA 2E8TA 2AETA 3W7FA 1N24A 2P1CA 5IMNA 3N5JF 5CG6A 3SDRA 2RAHA 5EAUA 5EASA 1UBVA 3P8RA 3DYGA 4KK2A 5DGMF 4LA6A 3SDVA 3SAEA 4EA2A 4EA0A 2E4OA 5HN8A 4XQTF 3QKCA 3S4JA 5HNAA 5ILKA 4N1ZF 5DGSF 2E94A 2Z4XA 3NF2A 2ZY1A 1WL0A 1YYQA 3OACA 4FP4A 3ACYA 3WEIA 5JV0F 4LXWA 4DHDA 2AZKA 2F94F 2J5CA 4NUAA 2F8ZF 3LVSA 3WJKA 5EROA 3OACB 1JFAA 4LFEA 5DHIA 2E8WA 5ILDA 3WCCA 4RXDA 3LK5A 5IN8A 4LPGF 3N6KF 1N21A 3WCHA 3M9UA 1WMWA 4WK5A 4EA1A 3RMGA 1N1ZA 1N1BA 1PS1A 4KKMA 3VJDA 3M02A 4GP1A 5IKAA 4H5DF 2E8UA 3V1XA 5EATA 3S9VA 3QQVA 5ERMA 2ZEUA 4P0VA 3WEGA 5C05A 2E8XA 3CKEA 4OGUA 3BNXA 4KVIA 2Z4YA 3LSNA 5IVGA 3RBMA 3VJCA 5IL3A 5HN9A 2AEKA 5IK9A 3RYEA 4K10A 2E8VA 3KBKA 1VG6A 5ILYA 3ADZA 4XQSF 4JXNA 1YHKA 1N20A 4LA5A 2AELA 3EZ3A 4LZ0A 1HXGA 4LTVA 5ILHA 4DEMF 4KPDA 3LOMA 3Q2ZA 3KRPA 5B0MA 1VG4A 2Q9YA 5B0IA 2E91A 5DJVF 4E9ZA 3KRPB 4L2XF 1DGPA 5B01A 5JA0F 1N23A 3VJ8A 4KQ5A 5B00A 3AQ0A 3TC1A 3TFNA 3WEHA 2Z7IA 5ERNA 2F7MF 3N5HF 4JZXA 4PVYF 3N1WF 1YHLA 1VG7A 2PS7A 4LLTA 3KRFA 3LGKA 5JV2F 3ZMBA 4DXJA 3N46F 2Z7HA 5DJRF 3KROA 3N45F 4XQRF 1V4HA 3AQBB 3KRFB 3P5RA 4KQSA 1FPSA 5ER8A 5IKHA 5A0KA 3ASXA 2I19A 3KROB 3M0GA 4KQUA 4NKEA 1UBWA 3ICZA 4E1EA 5I1UA 3TFPA 3KRAA 2ZCOA 3MZVA 3N0FA 2Q80A 1HM4A 3UCAA 4KVDA 2AZJA 4RXAA 3WEKA 4OKMA 2FTZA 3KRAB 2E93A 3PDEA 1WL3A 1YYSA 4JZBA 4NFJF 1EZFA 4MC0A 4LLSA 2FORA 5AYPA 1YV5A 4LFGA 4DWGA 3DYFA 5DHKA 1HXAA 3SDQA 3ZOUA 3IPIA 3WCMA 3Q1OA 4GAXA 5ILJA 3V66A 5DZ2A 1V4IA 3KRCA 4QXSF 4LUUA 4LTZA 1WKZA 1YHMA 5AHUB 3P8LA 2Q9ZA 3KB9A 3ACXA 3KRCB 3LLWA 5HN7A 5IMPA 3VJ9A 3ICMA 4KVWA 2OPMA 5KSXF 3WSBA 4NG6A 4NFKF 5B02A 1HM7A 3G4FA 3AE0A 4F6XA 1YYTA 3PKOA 4RXEA 1DI1A 3NPKA 3MAVA 4HD1A 4P0WA 3G4DA 5DJPF 1HXCA 2PS5A 2ZCQA 3OYRA 3EGTA 4LPHF 4MC3A 4KUXA 3OABA 1YQ7A 4JXYA 2F89F 3WCEA 5ILZA 3SDUA 4MC8A 5IL8A 4LZ3A 4GA3A 3LEEA 3OABB 3PYAA 4OKZA 4Q23A 2PS4A 3P5PA 4JVJF 2OA6A 3LG5A 3RYWA 4LIXA 1HX9A 4DI5A 1V4KA 2F8CF 2EWGA 3WCIA 2OPNA 3ZMCA 1VG3A 1YYRA 3B7LA 4UMJA 2E95A 1RQIA 5E8HA 1KIZA 3LZ9A 1WY0A 5B0KA 5DIQF 2Z4WA 1N22A 3ICNA 4RNQA 3N3DA 5B0JA 5DGNF 3PYBA 1JFGA 3ICKA 3LJIA 5DW7A 3ID0A 4N9UA 3LGZB 5IK6A 4QPFA 2O1OA 1WL1A 3ZL6A 2Z52A 2ZCRA 1KIYA 3NPRA 5A0IA 2AZLA 4FJQA 3TS7A 3WCFA 4OMGA 2J1OA 3M00A 4H5CF 3PH7A 3VJEA 3N0GA 3Q2QA 3N1VF 2E92A 4JYXA 2ZCSA 4KVYA 2Z4VA 3WEFA 2Q58A 2PS6A 3WCDA 4KWDA 4LFVF 4F6VA 5IM1A 3LDWA 3WC9A 3N49F 2Z78A 3WEJA 3AQCB 5E8LA 4DWBA 1RQJA 2OGDA 5AFXA 5B0LA 4P0XA 3DYHA 2H8OA 2J1PA 3WJNA 4DZWA 2PS8A 3CC9A 1VG2A 3WCGA 3CP6A 1V4EA 3TFVA 4RXCA 4E9UA 3LMDA 5B03A 3NRIA 1UBXA 3WCLA 2E90A 2F9KF 2ZEVA 4OMHA 3VJBA 4F62A 5IMIA 3ZCDA 4H5EF 1V4JA 1YJ4A 4KFAA 3VJAA 3EFQA 3Q30A 2ONHA 5JUZF 5A0JA 2F92F 4NKFA 5CG5A 5JV1F 3WCAA 4LOBA 3WE9A 3WCBA 4ZQ8A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5E8K A;  3N3L F;  4RYP A;  3BNY A;  2Z4Z A;  3M01 A;  3P41 A;  5AEL A;  1RTR A;  3SDT A;  4KPJ A;  4PVX F;  1YYU A;  4GP2 A;  2QIS A;  1UBY A;  3WCJ A;  3WSA A;  3V1V A;  2VF6 A;  4NFI F;  2ONG A;  3IBA A;  5IK0 A;  1ZW5 A;  1WL2 A;  4LZC A;  2DH4 A;  2Z50 A;  3APZ A;  3WJO A;  3ACW A;  5ILI A;  5H9D A;  2E8T A;  2AET A;  3W7F A;  1N24 A;  2P1C A;  5IMN A;  3N5J F;  5CG6 A;  3SDR A;  2RAH A;  5EAU A;  5EAS A;  1UBV A;  3P8R A;  3DYG A;  4KK2 A;  5DGM F;  4LA6 A;  3SDV A;  3SAE A;  4EA2 A;  4EA0 A;  2E4O A;  5HN8 A;  4XQT F;  3QKC A;  3S4J A;  5HNA A;  5ILK A;  4N1Z F;  5DGS F;  2E94 A;  2Z4X A;  3NF2 A;  2ZY1 A;  1WL0 A;  1YYQ A;  3OAC A;  4FP4 A;  3ACY A;  3WEI A;  5JV0 F;  4LXW A;  4DHD A;  2AZK A;  2F94 F;  2J5C A;  4NUA A;  2F8Z F;  3LVS A;  3WJK A;  5ERO A;  3OAC B;  1JFA A;  4LFE A;  5DHI A;  2E8W A;  5ILD A;  3WCC A;  4RXD A;  3LK5 A;  5IN8 A;  4LPG F;  3N6K F;  1N21 A;  3WCH A;  3M9U A;  1WMW A;  4WK5 A;  4EA1 A;  3RMG A;  1N1Z A;  1N1B A;  1PS1 A;  4KKM A;  3VJD A;  3M02 A;  4GP1 A;  5IKA A;  4H5D F;  2E8U A;  3V1X A;  5EAT A;  3S9V A;  3QQV A;  5ERM A;  2ZEU A;  4P0V A;  3WEG A;  5C05 A;  2E8X A;  3CKE A;  4OGU A;  3BNX A;  4KVI A;  2Z4Y A;  3LSN A;  5IVG A;  3RBM A;  3VJC A;  5IL3 A;  5HN9 A;  2AEK A;  5IK9 A;  3RYE A;  4K10 A;  2E8V A;  3KBK A;  1VG6 A;  5ILY A;  3ADZ A;  4XQS F;  4JXN A;  1YHK A;  1N20 A;  4LA5 A;  2AEL A;  3EZ3 A;  4LZ0 A;  1HXG A;  4LTV A;  5ILH A;  4DEM F;  4KPD A;  3LOM A;  3Q2Z A;  3KRP A;  5B0M A;  1VG4 A;  2Q9Y A;  5B0I A;  2E91 A;  5DJV F;  4E9Z A;  3KRP B;  4L2X F;  1DGP A;  5B01 A;  5JA0 F;  1N23 A;  3VJ8 A;  4KQ5 A;  5B00 A;  3AQ0 A;  3TC1 A;  3TFN A;  3WEH A;  2Z7I A;  5ERN A;  2F7M F;  3N5H F;  4JZX A;  4PVY F;  3N1W F;  1YHL A;  1VG7 A;  2PS7 A;  4LLT A;  3KRF A;  3LGK A;  5JV2 F;  3ZMB A;  4DXJ A;  3N46 F;  2Z7H A;  5DJR F;  3KRO A;  3N45 F;  4XQR F;  1V4H A;  3AQB B;  3KRF B;  3P5R A;  4KQS A;  1FPS A;  5ER8 A;  5IKH A;  5A0K A;  3ASX A;  2I19 A;  3KRO B;  3M0G A;  4KQU A;  4NKE A;  1UBW A;  3ICZ A;  4E1E A;  5I1U A;  3TFP A;  3KRA A;  2ZCO A;  3MZV A;  3N0F A;  2Q80 A;  1HM4 A;  3UCA A;  4KVD A;  2AZJ A;  4RXA A;  3WEK A;  4OKM A;  2FTZ A;  3KRA B;  2E93 A;  3PDE A;  1WL3 A;  1YYS A;  4JZB A;  4NFJ F;  1EZF A;  4MC0 A;  4LLS A;  2FOR A;  5AYP A;  1YV5 A;  4LFG A;  4DWG A;  3DYF A;  5DHK A;  1HXA A;  3SDQ A;  3ZOU A;  3IPI A;  3WCM A;  3Q1O A;  4GAX A;  5ILJ A;  3V66 A;  5DZ2 A;  1V4I A;  3KRC A;  4QXS F;  4LUU A;  4LTZ A;  1WKZ A;  1YHM A;  5AHU B;  3P8L A;  2Q9Z A;  3KB9 A;  3ACX A;  3KRC B;  3LLW A;  5HN7 A;  5IMP A;  3VJ9 A;  3ICM A;  4KVW A;  2OPM A;  5KSX F;  3WSB A;  4NG6 A;  4NFK F;  5B02 A;  1HM7 A;  3G4F A;  3AE0 A;  4F6X A;  1YYT A;  3PKO A;  4RXE A;  1DI1 A;  3NPK A;  3MAV A;  4HD1 A;  4P0W A;  3G4D A;  5DJP F;  1HXC A;  2PS5 A;  2ZCQ A;  3OYR A;  3EGT A;  4LPH F;  4MC3 A;  4KUX A;  3OAB A;  1YQ7 A;  4JXY A;  2F89 F;  3WCE A;  5ILZ A;  3SDU A;  4MC8 A;  5IL8 A;  4LZ3 A;  4GA3 A;  3LEE A;  3OAB B;  3PYA A;  4OKZ A;  4Q23 A;  2PS4 A;  3P5P A;  4JVJ F;  2OA6 A;  3LG5 A;  3RYW A;  4LIX A;  1HX9 A;  4DI5 A;  1V4K A;  2F8C F;  2EWG A;  3WCI A;  2OPN A;  3ZMC A;  1VG3 A;  1YYR A;  3B7L A;  4UMJ A;  2E95 A;  1RQI A;  5E8H A;  1KIZ A;  3LZ9 A;  1WY0 A;  5B0K A;  5DIQ F;  2Z4W A;  1N22 A;  3ICN A;  4RNQ A;  3N3D A;  5B0J A;  5DGN F;  3PYB A;  1JFG A;  3ICK A;  3LJI A;  5DW7 A;  3ID0 A;  4N9U A;  3LGZ B;  5IK6 A;  4QPF A;  2O1O A;  1WL1 A;  3ZL6 A;  2Z52 A;  2ZCR A;  1KIY A;  3NPR A;  5A0I A;  2AZL A;  4FJQ A;  3TS7 A;  3WCF A;  4OMG A;  2J1O A;  3M00 A;  4H5C F;  3PH7 A;  3VJE A;  3N0G A;  3Q2Q A;  3N1V F;  2E92 A;  4JYX A;  2ZCS A;  4KVY A;  2Z4V A;  3WEF A;  2Q58 A;  2PS6 A;  3WCD A;  4KWD A;  4LFV F;  4F6V A;  5IM1 A;  3LDW A;  3WC9 A;  3N49 F;  2Z78 A;  3WEJ A;  3AQC B;  5E8L A;  4DWB A;  1RQJ A;  2OGD A;  5AFX A;  5B0L A;  4P0X A;  3DYH A;  2H8O A;  2J1P A;  3WJN A;  4DZW A;  2PS8 A;  3CC9 A;  1VG2 A;  3WCG A;  3CP6 A;  1V4E A;  3TFV A;  4RXC A;  4E9U A;  3LMD A;  5B03 A;  3NRI A;  1UBX A;  3WCL A;  2E90 A;  2F9K F;  2ZEV A;  4OMH A;  3VJB A;  4F62 A;  5IMI A;  3ZCD A;  4H5E F;  1V4J A;  1YJ4 A;  4KFA A;  3VJA A;  3EFQ A;  3Q30 A;  2ONH A;  5JUZ F;  5A0J A;  2F92 F;  4NKF A;  5CG5 A;  5JV1 F;  3WCA A;  4LOB A;  3WE9 A;  3WCB A;  4ZQ8 A; 
#chains in the Genus database with same CATH topology
 5E8K A;  3N3L F;  4RYP A;  3BNY A;  2Z4Z A;  3M01 A;  3P41 A;  5AEL A;  1RTR A;  3SDT A;  4KPJ A;  4PVX F;  1YYU A;  4GP2 A;  2QIS A;  1UBY A;  3WCJ A;  3WSA A;  3V1V A;  2VF6 A;  4NFI F;  2ONG A;  3IBA A;  5IK0 A;  1ZW5 A;  1WL2 A;  4LZC A;  2DH4 A;  2Z50 A;  3APZ A;  3WJO A;  3ACW A;  5ILI A;  5H9D A;  2E8T A;  2AET A;  3W7F A;  1N24 A;  2P1C A;  5IMN A;  3N5J F;  5CG6 A;  3SDR A;  2RAH A;  5EAU A;  5EAS A;  1UBV A;  3P8R A;  3DYG A;  4KK2 A;  5DGM F;  4LA6 A;  3SDV A;  3SAE A;  4EA2 A;  4EA0 A;  2E4O A;  5HN8 A;  4XQT F;  3QKC A;  3S4J A;  5HNA A;  5ILK A;  4N1Z F;  5DGS F;  2E94 A;  2Z4X A;  3NF2 A;  2ZY1 A;  1WL0 A;  1YYQ A;  3OAC A;  4FP4 A;  3ACY A;  3WEI A;  5JV0 F;  4LXW A;  4DHD A;  2AZK A;  2F94 F;  2J5C A;  4NUA A;  2F8Z F;  3LVS A;  3WJK A;  5ERO A;  3OAC B;  1JFA A;  4LFE A;  5DHI A;  2E8W A;  5ILD A;  3WCC A;  4RXD A;  3LK5 A;  5IN8 A;  4LPG F;  3N6K F;  1N21 A;  3WCH A;  3M9U A;  1WMW A;  4WK5 A;  4EA1 A;  3RMG A;  1N1Z A;  1N1B A;  1PS1 A;  4KKM A;  3VJD A;  3M02 A;  4GP1 A;  5IKA A;  4H5D F;  2E8U A;  3V1X A;  5EAT A;  3S9V A;  3QQV A;  5ERM A;  2ZEU A;  4P0V A;  3WEG A;  5C05 A;  2E8X A;  3CKE A;  4OGU A;  3BNX A;  4KVI A;  2Z4Y A;  3LSN A;  5IVG A;  3RBM A;  3VJC A;  5IL3 A;  5HN9 A;  2AEK A;  5IK9 A;  3RYE A;  4K10 A;  2E8V A;  3KBK A;  1VG6 A;  5ILY A;  3ADZ A;  4XQS F;  4JXN A;  1YHK A;  1N20 A;  4LA5 A;  2AEL A;  3EZ3 A;  4LZ0 A;  1HXG A;  4LTV A;  5ILH A;  4DEM F;  4KPD A;  3LOM A;  3Q2Z A;  3KRP A;  5B0M A;  1VG4 A;  2Q9Y A;  5B0I A;  2E91 A;  5DJV F;  4E9Z A;  3KRP B;  4L2X F;  1DGP A;  5B01 A;  5JA0 F;  1N23 A;  3VJ8 A;  4KQ5 A;  5B00 A;  3AQ0 A;  3TC1 A;  3TFN A;  3WEH A;  2Z7I A;  5ERN A;  2F7M F;  3N5H F;  4JZX A;  4PVY F;  3N1W F;  1YHL A;  1VG7 A;  2PS7 A;  4LLT A;  3KRF A;  3LGK A;  5JV2 F;  3ZMB A;  4DXJ A;  3N46 F;  2Z7H A;  5DJR F;  3KRO A;  3N45 F;  4XQR F;  1V4H A;  3AQB B;  3KRF B;  3P5R A;  4KQS A;  1FPS A;  5ER8 A;  5IKH A;  5A0K A;  3ASX A;  2I19 A;  3KRO B;  3M0G A;  4KQU A;  4NKE A;  1UBW A;  3ICZ A;  4E1E A;  5I1U A;  3TFP A;  3KRA A;  2ZCO A;  3MZV A;  3N0F A;  2Q80 A;  1HM4 A;  3UCA A;  4KVD A;  2AZJ A;  4RXA A;  3WEK A;  4OKM A;  2FTZ A;  3KRA B;  2E93 A;  3PDE A;  1WL3 A;  1YYS A;  4JZB A;  4NFJ F;  1EZF A;  4MC0 A;  4LLS A;  2FOR A;  5AYP A;  1YV5 A;  4LFG A;  4DWG A;  3DYF A;  5DHK A;  1HXA A;  3SDQ A;  3ZOU A;  3IPI A;  3WCM A;  3Q1O A;  4GAX A;  5ILJ A;  3V66 A;  5DZ2 A;  1V4I A;  3KRC A;  4QXS F;  4LUU A;  4LTZ A;  1WKZ A;  1YHM A;  5AHU B;  3P8L A;  2Q9Z A;  3KB9 A;  3ACX A;  3KRC B;  3LLW A;  5HN7 A;  5IMP A;  3VJ9 A;  3ICM A;  4KVW A;  2OPM A;  5KSX F;  3WSB A;  4NG6 A;  4NFK F;  5B02 A;  1HM7 A;  3G4F A;  3AE0 A;  4F6X A;  1YYT A;  3PKO A;  4RXE A;  1DI1 A;  3NPK A;  3MAV A;  4HD1 A;  4P0W A;  3G4D A;  5DJP F;  1HXC A;  2PS5 A;  2ZCQ A;  3OYR A;  3EGT A;  4LPH F;  4MC3 A;  4KUX A;  3OAB A;  1YQ7 A;  4JXY A;  2F89 F;  3WCE A;  5ILZ A;  3SDU A;  4MC8 A;  5IL8 A;  4LZ3 A;  4GA3 A;  3LEE A;  3OAB B;  3PYA A;  4OKZ A;  4Q23 A;  2PS4 A;  3P5P A;  4JVJ F;  2OA6 A;  3LG5 A;  3RYW A;  4LIX A;  1HX9 A;  4DI5 A;  1V4K A;  2F8C F;  2EWG A;  3WCI A;  2OPN A;  3ZMC A;  1VG3 A;  1YYR A;  3B7L A;  4UMJ A;  2E95 A;  1RQI A;  5E8H A;  1KIZ A;  3LZ9 A;  1WY0 A;  5B0K A;  5DIQ F;  2Z4W A;  1N22 A;  3ICN A;  4RNQ A;  3N3D A;  5B0J A;  5DGN F;  3PYB A;  1JFG A;  3ICK A;  3LJI A;  5DW7 A;  3ID0 A;  4N9U A;  3LGZ B;  5IK6 A;  4QPF A;  2O1O A;  1WL1 A;  3ZL6 A;  2Z52 A;  2ZCR A;  1KIY A;  3NPR A;  5A0I A;  2AZL A;  4FJQ A;  3TS7 A;  3WCF A;  4OMG A;  2J1O A;  3M00 A;  4H5C F;  3PH7 A;  3VJE A;  3N0G A;  3Q2Q A;  3N1V F;  2E92 A;  4JYX A;  2ZCS A;  4KVY A;  2Z4V A;  3WEF A;  2Q58 A;  2PS6 A;  3WCD A;  4KWD A;  4LFV F;  4F6V A;  5IM1 A;  3LDW A;  3WC9 A;  3N49 F;  2Z78 A;  3WEJ A;  3AQC B;  5E8L A;  4DWB A;  1RQJ A;  2OGD A;  5AFX A;  5B0L A;  4P0X A;  3DYH A;  2H8O A;  2J1P A;  3WJN A;  4DZW A;  2PS8 A;  3CC9 A;  1VG2 A;  3WCG A;  3CP6 A;  1V4E A;  3TFV A;  4RXC A;  4E9U A;  3LMD A;  5B03 A;  3NRI A;  1UBX A;  3WCL A;  2E90 A;  2F9K F;  2ZEV A;  4OMH A;  3VJB A;  4F62 A;  5IMI A;  3ZCD A;  4H5E F;  1V4J A;  1YJ4 A;  4KFA A;  3VJA A;  3EFQ A;  3Q30 A;  2ONH A;  5JUZ F;  5A0J A;  2F92 F;  4NKF A;  5CG5 A;  5JV1 F;  3WCA A;  4LOB A;  3WE9 A;  3WCB A;  4ZQ8 A; 
#chains in the Genus database with same CATH homology
 5E8K A;  3N3L F;  4RYP A;  3BNY A;  2Z4Z A;  3M01 A;  3P41 A;  5AEL A;  1RTR A;  3SDT A;  4KPJ A;  4PVX F;  1YYU A;  4GP2 A;  2QIS A;  1UBY A;  3WCJ A;  3WSA A;  3V1V A;  2VF6 A;  4NFI F;  2ONG A;  3IBA A;  5IK0 A;  1ZW5 A;  1WL2 A;  4LZC A;  2DH4 A;  2Z50 A;  3APZ A;  3WJO A;  3ACW A;  5ILI A;  5H9D A;  2E8T A;  2AET A;  3W7F A;  1N24 A;  2P1C A;  5IMN A;  3N5J F;  5CG6 A;  3SDR A;  2RAH A;  5EAU A;  5EAS A;  1UBV A;  3P8R A;  3DYG A;  4KK2 A;  5DGM F;  4LA6 A;  3SDV A;  3SAE A;  4EA2 A;  4EA0 A;  2E4O A;  5HN8 A;  4XQT F;  3QKC A;  3S4J A;  5HNA A;  5ILK A;  4N1Z F;  5DGS F;  2E94 A;  2Z4X A;  3NF2 A;  2ZY1 A;  1WL0 A;  1YYQ A;  3OAC A;  4FP4 A;  3ACY A;  3WEI A;  5JV0 F;  4LXW A;  4DHD A;  2AZK A;  2F94 F;  2J5C A;  4NUA A;  2F8Z F;  3LVS A;  3WJK A;  5ERO A;  3OAC B;  1JFA A;  4LFE A;  5DHI A;  2E8W A;  5ILD A;  3WCC A;  4RXD A;  3LK5 A;  5IN8 A;  4LPG F;  3N6K F;  1N21 A;  3WCH A;  3M9U A;  1WMW A;  4WK5 A;  4EA1 A;  3RMG A;  1N1Z A;  1N1B A;  1PS1 A;  4KKM A;  3VJD A;  3M02 A;  4GP1 A;  5IKA A;  4H5D F;  2E8U A;  3V1X A;  5EAT A;  3S9V A;  3QQV A;  5ERM A;  2ZEU A;  4P0V A;  3WEG A;  5C05 A;  2E8X A;  3CKE A;  4OGU A;  3BNX A;  4KVI A;  2Z4Y A;  3LSN A;  5IVG A;  3RBM A;  3VJC A;  5IL3 A;  5HN9 A;  2AEK A;  5IK9 A;  3RYE A;  4K10 A;  2E8V A;  3KBK A;  1VG6 A;  5ILY A;  3ADZ A;  4XQS F;  4JXN A;  1YHK A;  1N20 A;  4LA5 A;  2AEL A;  3EZ3 A;  4LZ0 A;  1HXG A;  4LTV A;  5ILH A;  4DEM F;  4KPD A;  3LOM A;  3Q2Z A;  3KRP A;  5B0M A;  1VG4 A;  2Q9Y A;  5B0I A;  2E91 A;  5DJV F;  4E9Z A;  3KRP B;  4L2X F;  1DGP A;  5B01 A;  5JA0 F;  1N23 A;  3VJ8 A;  4KQ5 A;  5B00 A;  3AQ0 A;  3TC1 A;  3TFN A;  3WEH A;  2Z7I A;  5ERN A;  2F7M F;  3N5H F;  4JZX A;  4PVY F;  3N1W F;  1YHL A;  1VG7 A;  2PS7 A;  4LLT A;  3KRF A;  3LGK A;  5JV2 F;  3ZMB A;  4DXJ A;  3N46 F;  2Z7H A;  5DJR F;  3KRO A;  3N45 F;  4XQR F;  1V4H A;  3AQB B;  3KRF B;  3P5R A;  4KQS A;  1FPS A;  5ER8 A;  5IKH A;  5A0K A;  3ASX A;  2I19 A;  3KRO B;  3M0G A;  4KQU A;  4NKE A;  1UBW A;  3ICZ A;  4E1E A;  5I1U A;  3TFP A;  3KRA A;  2ZCO A;  3MZV A;  3N0F A;  2Q80 A;  1HM4 A;  3UCA A;  4KVD A;  2AZJ A;  4RXA A;  3WEK A;  4OKM A;  2FTZ A;  3KRA B;  2E93 A;  3PDE A;  1WL3 A;  1YYS A;  4JZB A;  4NFJ F;  1EZF A;  4MC0 A;  4LLS A;  2FOR A;  5AYP A;  1YV5 A;  4LFG A;  4DWG A;  3DYF A;  5DHK A;  1HXA A;  3SDQ A;  3ZOU A;  3IPI A;  3WCM A;  3Q1O A;  4GAX A;  5ILJ A;  3V66 A;  5DZ2 A;  1V4I A;  3KRC A;  4QXS F;  4LUU A;  4LTZ A;  1WKZ A;  1YHM A;  5AHU B;  3P8L A;  2Q9Z A;  3KB9 A;  3ACX A;  3KRC B;  3LLW A;  5HN7 A;  5IMP A;  3VJ9 A;  3ICM A;  4KVW A;  2OPM A;  5KSX F;  3WSB A;  4NG6 A;  4NFK F;  5B02 A;  1HM7 A;  3G4F A;  3AE0 A;  4F6X A;  1YYT A;  3PKO A;  4RXE A;  1DI1 A;  3NPK A;  3MAV A;  4HD1 A;  4P0W A;  3G4D A;  5DJP F;  1HXC A;  2PS5 A;  2ZCQ A;  3OYR A;  3EGT A;  4LPH F;  4MC3 A;  4KUX A;  3OAB A;  1YQ7 A;  4JXY A;  2F89 F;  3WCE A;  5ILZ A;  3SDU A;  4MC8 A;  5IL8 A;  4LZ3 A;  4GA3 A;  3LEE A;  3OAB B;  3PYA A;  4OKZ A;  4Q23 A;  2PS4 A;  3P5P A;  4JVJ F;  2OA6 A;  3LG5 A;  3RYW A;  4LIX A;  1HX9 A;  4DI5 A;  1V4K A;  2F8C F;  2EWG A;  3WCI A;  2OPN A;  3ZMC A;  1VG3 A;  1YYR A;  3B7L A;  4UMJ A;  2E95 A;  1RQI A;  5E8H A;  1KIZ A;  3LZ9 A;  1WY0 A;  5B0K A;  5DIQ F;  2Z4W A;  1N22 A;  3ICN A;  4RNQ A;  3N3D A;  5B0J A;  5DGN F;  3PYB A;  1JFG A;  3ICK A;  3LJI A;  5DW7 A;  3ID0 A;  4N9U A;  3LGZ B;  5IK6 A;  4QPF A;  2O1O A;  1WL1 A;  3ZL6 A;  2Z52 A;  2ZCR A;  1KIY A;  3NPR A;  5A0I A;  2AZL A;  4FJQ A;  3TS7 A;  3WCF A;  4OMG A;  2J1O A;  3M00 A;  4H5C F;  3PH7 A;  3VJE A;  3N0G A;  3Q2Q A;  3N1V F;  2E92 A;  4JYX A;  2ZCS A;  4KVY A;  2Z4V A;  3WEF A;  2Q58 A;  2PS6 A;  3WCD A;  4KWD A;  4LFV F;  4F6V A;  5IM1 A;  3LDW A;  3WC9 A;  3N49 F;  2Z78 A;  3WEJ A;  3AQC B;  5E8L A;  4DWB A;  1RQJ A;  2OGD A;  5AFX A;  5B0L A;  4P0X A;  3DYH A;  2H8O A;  2J1P A;  3WJN A;  4DZW A;  2PS8 A;  3CC9 A;  1VG2 A;  3WCG A;  3CP6 A;  1V4E A;  3TFV A;  4RXC A;  4E9U A;  3LMD A;  5B03 A;  3NRI A;  1UBX A;  3WCL A;  2E90 A;  2F9K F;  2ZEV A;  4OMH A;  3VJB A;  4F62 A;  5IMI A;  3ZCD A;  4H5E F;  1V4J A;  1YJ4 A;  4KFA A;  3VJA A;  3EFQ A;  3Q30 A;  2ONH A;  5JUZ F;  5A0J A;  2F92 F;  4NKF A;  5CG5 A;  5JV1 F;  3WCA A;  4LOB A;  3WE9 A;  3WCB A;  4ZQ8 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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