4F6XA

Crystal structure of dehydrosqualene synthase (crtm) from s. aureus complexed with bph-1112
Total Genus 113
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
113
sequence length
284
structure length
281
Chain Sequence
MTMMDMNFKYCHKIMKKHSKSFSYAFDLLPEDQRKAVWAIYAVCRKIDDSIDDIQFLNQIKEDIQSIEKYPYEYHHFQSDRRIMMALQHVAQHKNIAFQSFYNLIDTVYKDQHFTMFETDAELFGYCYGVAGTVGEVLTPILSDHETHQTYDVARRLGESLQLINILRDVGEDFENERIYFSKQRLKQYEVDIAEVYQNGVNNHYIDLWEYYAAIAEKDFRDVMDQIKVFSIEAQPIIELAARIYIEILDEVRQANYTLHERVFVEKRKKAKLFHEINSKY
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Transferase/transferase inhibitor
source organism Staphylococcus aureus
publication title HIV-1 Integrase Inhibitor-Inspired Antibacterials Targeting Isoprenoid Biosynthesis.
pubmed doi rcsb
molecule keywords Dehydrosqualene synthase
total genus 113
structure length 281
sequence length 284
ec nomenclature ec 2.5.1.96: 4,4'-diapophytoene synthase.
pdb deposition date 2012-05-15

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00494 SQS_PSY Squalene/phytoene synthase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.600.10 Mainly Alpha Orthogonal Bundle Farnesyl Diphosphate Synthase Farnesyl Diphosphate Synthase 4f6xA00
4LPHF 5ILZA 3RYEA 1UBXA 4JXYA 3QQVA 5B02A 3ZCDA 5A0IA 5IMIA 5A0KA 3RMGA 4KVIA 3ICKA 4JZXA 2E8TA 4N1ZF 4KK2A 4LUUA 4MC0A 3WEGA 4LTVA 3SDQA 3LMDA 5EAUA 4DZWA 4KVDA 4RXEA 3KRAB 5ILIA 4KQUA 1VG6A 3IPIA 3P41A 2AETA 2F8ZF 5ILDA 1YHKA 4H5DF 3WEHA 4NFJF 4LLSA 1WMWA 3WJOA 3P8LA 3P5RA 4WK5A 5IK6A 5B0JA 5IN8A 4RNQA 3CC9A 4GA3A 3KRAA 5IMPA 4JZBA 3Q2ZA 4NKFA 3P5PA 4NUAA 3OYRA 5I1UA 5JV2F 3ZMCA 3NPRA 1JFAA 3APZA 3Q2QA 4KQ5A 5E8LA 3UCAA 4F6VA 4MC8A 4XQRF 1WL1A 5ERMA 1YV5A 1EZFA 2AEKA 4DEMF 2FTZA 3V66A 4OKMA 4E9UA 1DGPA 2Z78A 4GP2A 3AQCB 1N22A 5AFXA 2F94F 3CP6A 3M01A 3WCBA 3LLWA 5IMNA 4LPGF 2EWGA 1V4HA 3KRFB 1WKZA 3ADZA 4XQTF 2RAHA 5ERNA 3SDRA 2ZCRA 5ILHA 4P0WA 2H8OA 5B01A 4KWDA 1ZW5A 5IL3A 4KUXA 1V4EA 4F6XA 2DH4A 3TS7A 4KPJA 5IKAA 3LEEA 3DYGA 1UBYA 5JUZF 3MZVA 3WC9A 3NPKA 3LZ9A 2F89F 5EROA 4LXWA 4QPFA 5IK0A 3KRFA 5ILYA 4OGUA 3VJ8A 3ICMA 4KVWA 3RYWA 2PS5A 4OMGA 2E8XA 4RXAA 1PS1A 2OGDA 4F62A 3WCJA 2QISA 4E9ZA 3WJNA 2J1OA 3KBKA 2E94A 3Q1OA 2OPMA 3N0FA 3WCLA 4LA6A 2Z52A 4KPDA 3OABA 1YHMA 3AE0A 1HX9A 3N45F 3TC1A 4LLTA 4DWBA 5DGNF 5A0JA 2Z4VA 4KQSA 3WEIA 1N20A 4H5CF 3KB9A 5JV0F 4KVYA 3OACA 5JA0F 5CG5A 3WCCA 3Q30A 2AZJA 1V4IA 5HN8A 3WCIA 3N6KF 3TFNA 5EASA 2AELA 3WJKA 4QXSF 1HM4A 5E8HA 4XQSF 2ZY1A 3PYBA 3S9VA 1WL3A 5B0MA 3WCEA 3V1VA 4PVYF 4LFVF 3S4JA 3NRIA 3SDVA 3N3LF 4DWGA 4LOBA 1HXGA 3VJCA 4N9UA 1V4JA 4E1EA 3NF2A 5IK9A 1KIYA 2VF6A 3KROB 3N3DA 5IL8A 3G4FA 5DJRF 2Z7HA 3PDEA 1N1ZA 1N24A 5HN9A 2E91A 3LGZB 4PVXF 5KSXF 2O1OA 5DZ2A 3N0GA 3TFVA 3G4DA 1VG3A 4RYPA 2Z4WA 2ZCOA 3M9UA 2Z7IA 3LGKA 3M0GA 1N23A 4P0VA 3VJAA 3KROA 2Q80A 2PS6A 5B0IA 2PS7A 4H5EF 5AHUB 3LVSA 3WCFA 2Z4XA 3WSAA 2ONHA 2E8WA 3ICNA 5C05A 3CKEA 3VJBA 1RQJA 2P1CA 4JVJF 5DJVF 3ZMBA 3WCHA 5DIQF 3BNXA 5IM1A 3ACXA 3M02A 3LJIA 3M00A 3DYHA 5DGSF 1YHLA 1HM7A 5IKHA 5E8KA 1WL0A 3N1WF 5B0KA 4DI5A 5CG6A 3KRCB 3ZL6A 2AZKA 4LZCA 3V1XA 3EFQA 5DJPF 4UMJA 2E95A 3IBAA 2OA6A 3VJDA 3N5HF 4LTZA 3WCMA 1YYQA 4EA0A 3W7FA 3LOMA 3N1VF 5ER8A 1VG2A 3SAEA 3WEJA 1YYRA 3PYAA 1JFGA 2PS8A 3WEFA 3KRCA 3ACYA 3P8RA 3N49F 4P0XA 4FJQA 5B0LA 4LFEA 3BNYA 3WCAA 4KKMA 3PH7A 2F9KF 5AYPA 3KRPB 1HXAA 5HN7A 4KFAA 5DHKA 3N5JF 3VJEA 1YQ7A 3VJ9A 3AQ0A 5ILKA 4GAXA 2E4OA 2E93A 1DI1A 2ZCSA 3DYFA 4NKEA 3ACWA 1YYTA 4EA1A 4RXDA 3KRPA 3ICZA 1HXCA 2F8CF 3B7LA 4JXNA 1VG4A 2ONGA 1RQIA 3PKOA 3ZOUA 2E8UA 5AELA 1YYSA 1N21A 5IVGA 3ASXA 2ZCQA 4OKZA 4L2XF 4JYXA 3LDWA 3WEKA 5DW7A 3QKCA 2OPNA 5DGMF 2E90A 2ZEUA 2F7MF 5HNAA 3LK5A 1YYUA 2FORA 2Z50A 2Q9ZA 1VG7A 4LZ3A 1V4KA 4LA5A 4RXCA 3WCDA 2F92F 2AZLA 3WCGA 4DXJA 2E8VA 4HD1A 3MAVA 2Q9YA 4FP4A 2E92A 5B00A 3EGTA 4NG6A 4Q23A 4ZQ8A 2ZEVA 1WY0A 5EATA 5DHIA 3WE9A 3N46F 3TFPA 4EA2A 1UBVA 1N1BA 1RTRA 4LIXA 4NFKF 3LSNA 3SDTA 2J5CA 1KIZA 4LZ0A 3AQBB 5B03A 2PS4A 4K10A 3RBMA 1YJ4A 1WL2A 2I19A 5ILJA 2Z4ZA 5JV1F 3OABB 4DHDA 3ID0A 2J1PA 2Z4YA 4LFGA 1FPSA 3SDUA 3WSBA 1UBWA 4NFIF 2Q58A 3LG5A 4GP1A 4OMHA 5H9DA 4MC3A 3EZ3A 3OACB
chains in the Genus database with same CATH superfamily
4LPHF 5ILZA 3RYEA 1UBXA 4JXYA 3QQVA 5B02A 3ZCDA 5A0IA 5IMIA 5A0KA 3RMGA 4KVIA 3ICKA 4JZXA 2E8TA 4N1ZF 4KK2A 4LUUA 4MC0A 3WEGA 4LTVA 3SDQA 3LMDA 5EAUA 4DZWA 4KVDA 4RXEA 3KRAB 5ILIA 4KQUA 1VG6A 3IPIA 3P41A 2AETA 2F8ZF 5ILDA 1YHKA 4H5DF 3WEHA 4NFJF 4LLSA 1WMWA 3WJOA 3P8LA 3P5RA 4WK5A 5IK6A 5B0JA 5IN8A 4RNQA 3CC9A 4GA3A 3KRAA 5IMPA 4JZBA 3Q2ZA 4NKFA 3P5PA 4NUAA 3OYRA 5I1UA 5JV2F 3ZMCA 3NPRA 1JFAA 3APZA 3Q2QA 4KQ5A 5E8LA 3UCAA 4F6VA 4MC8A 4XQRF 1WL1A 5ERMA 1YV5A 1EZFA 2AEKA 4DEMF 2FTZA 3V66A 4OKMA 4E9UA 1DGPA 2Z78A 4GP2A 3AQCB 1N22A 5AFXA 2F94F 3CP6A 3M01A 3WCBA 3LLWA 5IMNA 4LPGF 2EWGA 1V4HA 3KRFB 1WKZA 3ADZA 4XQTF 2RAHA 5ERNA 3SDRA 2ZCRA 5ILHA 4P0WA 2H8OA 5B01A 4KWDA 1ZW5A 5IL3A 4KUXA 1V4EA 4F6XA 2DH4A 3TS7A 4KPJA 5IKAA 3LEEA 3DYGA 1UBYA 5JUZF 3MZVA 3WC9A 3NPKA 3LZ9A 2F89F 5EROA 4LXWA 4QPFA 5IK0A 3KRFA 5ILYA 4OGUA 3VJ8A 3ICMA 4KVWA 3RYWA 2PS5A 4OMGA 2E8XA 4RXAA 1PS1A 2OGDA 4F62A 3WCJA 2QISA 4E9ZA 3WJNA 2J1OA 3KBKA 2E94A 3Q1OA 2OPMA 3N0FA 3WCLA 4LA6A 2Z52A 4KPDA 3OABA 1YHMA 3AE0A 1HX9A 3N45F 3TC1A 4LLTA 4DWBA 5DGNF 5A0JA 2Z4VA 4KQSA 3WEIA 1N20A 4H5CF 3KB9A 5JV0F 4KVYA 3OACA 5JA0F 5CG5A 3WCCA 3Q30A 2AZJA 1V4IA 5HN8A 3WCIA 3N6KF 3TFNA 5EASA 2AELA 3WJKA 4QXSF 1HM4A 5E8HA 4XQSF 2ZY1A 3PYBA 3S9VA 1WL3A 5B0MA 3WCEA 3V1VA 4PVYF 4LFVF 3S4JA 3NRIA 3SDVA 3N3LF 4DWGA 4LOBA 1HXGA 3VJCA 4N9UA 1V4JA 4E1EA 3NF2A 5IK9A 1KIYA 2VF6A 3KROB 3N3DA 5IL8A 3G4FA 5DJRF 2Z7HA 3PDEA 1N1ZA 1N24A 5HN9A 2E91A 3LGZB 4PVXF 5KSXF 2O1OA 5DZ2A 3N0GA 3TFVA 3G4DA 1VG3A 4RYPA 2Z4WA 2ZCOA 3M9UA 2Z7IA 3LGKA 3M0GA 1N23A 4P0VA 3VJAA 3KROA 2Q80A 2PS6A 5B0IA 2PS7A 4H5EF 5AHUB 3LVSA 3WCFA 2Z4XA 3WSAA 2ONHA 2E8WA 3ICNA 5C05A 3CKEA 3VJBA 1RQJA 2P1CA 4JVJF 5DJVF 3ZMBA 3WCHA 5DIQF 3BNXA 5IM1A 3ACXA 3M02A 3LJIA 3M00A 3DYHA 5DGSF 1YHLA 1HM7A 5IKHA 5E8KA 1WL0A 3N1WF 5B0KA 4DI5A 5CG6A 3KRCB 3ZL6A 2AZKA 4LZCA 3V1XA 3EFQA 5DJPF 4UMJA 2E95A 3IBAA 2OA6A 3VJDA 3N5HF 4LTZA 3WCMA 1YYQA 4EA0A 3W7FA 3LOMA 3N1VF 5ER8A 1VG2A 3SAEA 3WEJA 1YYRA 3PYAA 1JFGA 2PS8A 3WEFA 3KRCA 3ACYA 3P8RA 3N49F 4P0XA 4FJQA 5B0LA 4LFEA 3BNYA 3WCAA 4KKMA 3PH7A 2F9KF 5AYPA 3KRPB 1HXAA 5HN7A 4KFAA 5DHKA 3N5JF 3VJEA 1YQ7A 3VJ9A 3AQ0A 5ILKA 4GAXA 2E4OA 2E93A 1DI1A 2ZCSA 3DYFA 4NKEA 3ACWA 1YYTA 4EA1A 4RXDA 3KRPA 3ICZA 1HXCA 2F8CF 3B7LA 4JXNA 1VG4A 2ONGA 1RQIA 3PKOA 3ZOUA 2E8UA 5AELA 1YYSA 1N21A 5IVGA 3ASXA 2ZCQA 4OKZA 4L2XF 4JYXA 3LDWA 3WEKA 5DW7A 3QKCA 2OPNA 5DGMF 2E90A 2ZEUA 2F7MF 5HNAA 3LK5A 1YYUA 2FORA 2Z50A 2Q9ZA 1VG7A 4LZ3A 1V4KA 4LA5A 4RXCA 3WCDA 2F92F 2AZLA 3WCGA 4DXJA 2E8VA 4HD1A 3MAVA 2Q9YA 4FP4A 2E92A 5B00A 3EGTA 4NG6A 4Q23A 4ZQ8A 2ZEVA 1WY0A 5EATA 5DHIA 3WE9A 3N46F 3TFPA 4EA2A 1UBVA 1N1BA 1RTRA 4LIXA 4NFKF 3LSNA 3SDTA 2J5CA 1KIZA 4LZ0A 3AQBB 5B03A 2PS4A 4K10A 3RBMA 1YJ4A 1WL2A 2I19A 5ILJA 2Z4ZA 5JV1F 3OABB 4DHDA 3ID0A 2J1PA 2Z4YA 4LFGA 1FPSA 3SDUA 3WSBA 1UBWA 4NFIF 2Q58A 3LG5A 4GP1A 4OMHA 5H9DA 4MC3A 3EZ3A 3OACB
chains in the Genus database with same CATH topology
4LPHF 5ILZA 3RYEA 1UBXA 4JXYA 3QQVA 5B02A 3ZCDA 5A0IA 5IMIA 5A0KA 3RMGA 4KVIA 3ICKA 4JZXA 2E8TA 4N1ZF 4KK2A 4LUUA 4MC0A 3WEGA 4LTVA 3SDQA 3LMDA 5EAUA 4DZWA 4KVDA 4RXEA 3KRAB 5ILIA 4KQUA 1VG6A 3IPIA 3P41A 2AETA 2F8ZF 5ILDA 1YHKA 4H5DF 3WEHA 4NFJF 4LLSA 1WMWA 3WJOA 3P8LA 3P5RA 4WK5A 5IK6A 5B0JA 5IN8A 4RNQA 3CC9A 4GA3A 3KRAA 5IMPA 4JZBA 3Q2ZA 4NKFA 3P5PA 4NUAA 3OYRA 5I1UA 5JV2F 3ZMCA 3NPRA 1JFAA 3APZA 3Q2QA 4KQ5A 5E8LA 3UCAA 4F6VA 4MC8A 4XQRF 1WL1A 5ERMA 1YV5A 1EZFA 2AEKA 4DEMF 2FTZA 3V66A 4OKMA 4E9UA 1DGPA 2Z78A 4GP2A 3AQCB 1N22A 5AFXA 2F94F 3CP6A 3M01A 3WCBA 3LLWA 5IMNA 4LPGF 2EWGA 1V4HA 3KRFB 1WKZA 3ADZA 4XQTF 2RAHA 5ERNA 3SDRA 2ZCRA 5ILHA 4P0WA 2H8OA 5B01A 4KWDA 1ZW5A 5IL3A 4KUXA 1V4EA 4F6XA 2DH4A 3TS7A 4KPJA 5IKAA 3LEEA 3DYGA 1UBYA 5JUZF 3MZVA 3WC9A 3NPKA 3LZ9A 2F89F 5EROA 4LXWA 4QPFA 5IK0A 3KRFA 5ILYA 4OGUA 3VJ8A 3ICMA 4KVWA 3RYWA 2PS5A 4OMGA 2E8XA 4RXAA 1PS1A 2OGDA 4F62A 3WCJA 2QISA 4E9ZA 3WJNA 2J1OA 3KBKA 2E94A 3Q1OA 2OPMA 3N0FA 3WCLA 4LA6A 2Z52A 4KPDA 3OABA 1YHMA 3AE0A 1HX9A 3N45F 3TC1A 4LLTA 4DWBA 5DGNF 5A0JA 2Z4VA 4KQSA 3WEIA 1N20A 4H5CF 3KB9A 5JV0F 4KVYA 3OACA 5JA0F 5CG5A 3WCCA 3Q30A 2AZJA 1V4IA 5HN8A 3WCIA 3N6KF 3TFNA 5EASA 2AELA 3WJKA 4QXSF 1HM4A 5E8HA 4XQSF 2ZY1A 3PYBA 3S9VA 1WL3A 5B0MA 3WCEA 3V1VA 4PVYF 4LFVF 3S4JA 3NRIA 3SDVA 3N3LF 4DWGA 4LOBA 1HXGA 3VJCA 4N9UA 1V4JA 4E1EA 3NF2A 5IK9A 1KIYA 2VF6A 3KROB 3N3DA 5IL8A 3G4FA 5DJRF 2Z7HA 3PDEA 1N1ZA 1N24A 5HN9A 2E91A 3LGZB 4PVXF 5KSXF 2O1OA 5DZ2A 3N0GA 3TFVA 3G4DA 1VG3A 4RYPA 2Z4WA 2ZCOA 3M9UA 2Z7IA 3LGKA 3M0GA 1N23A 4P0VA 3VJAA 3KROA 2Q80A 2PS6A 5B0IA 2PS7A 4H5EF 5AHUB 3LVSA 3WCFA 2Z4XA 3WSAA 2ONHA 2E8WA 3ICNA 5C05A 3CKEA 3VJBA 1RQJA 2P1CA 4JVJF 5DJVF 3ZMBA 3WCHA 5DIQF 3BNXA 5IM1A 3ACXA 3M02A 3LJIA 3M00A 3DYHA 5DGSF 1YHLA 1HM7A 5IKHA 5E8KA 1WL0A 3N1WF 5B0KA 4DI5A 5CG6A 3KRCB 3ZL6A 2AZKA 4LZCA 3V1XA 3EFQA 5DJPF 4UMJA 2E95A 3IBAA 2OA6A 3VJDA 3N5HF 4LTZA 3WCMA 1YYQA 4EA0A 3W7FA 3LOMA 3N1VF 5ER8A 1VG2A 3SAEA 3WEJA 1YYRA 3PYAA 1JFGA 2PS8A 3WEFA 3KRCA 3ACYA 3P8RA 3N49F 4P0XA 4FJQA 5B0LA 4LFEA 3BNYA 3WCAA 4KKMA 3PH7A 2F9KF 5AYPA 3KRPB 1HXAA 5HN7A 4KFAA 5DHKA 3N5JF 3VJEA 1YQ7A 3VJ9A 3AQ0A 5ILKA 4GAXA 2E4OA 2E93A 1DI1A 2ZCSA 3DYFA 4NKEA 3ACWA 1YYTA 4EA1A 4RXDA 3KRPA 3ICZA 1HXCA 2F8CF 3B7LA 4JXNA 1VG4A 2ONGA 1RQIA 3PKOA 3ZOUA 2E8UA 5AELA 1YYSA 1N21A 5IVGA 3ASXA 2ZCQA 4OKZA 4L2XF 4JYXA 3LDWA 3WEKA 5DW7A 3QKCA 2OPNA 5DGMF 2E90A 2ZEUA 2F7MF 5HNAA 3LK5A 1YYUA 2FORA 2Z50A 2Q9ZA 1VG7A 4LZ3A 1V4KA 4LA5A 4RXCA 3WCDA 2F92F 2AZLA 3WCGA 4DXJA 2E8VA 4HD1A 3MAVA 2Q9YA 4FP4A 2E92A 5B00A 3EGTA 4NG6A 4Q23A 4ZQ8A 2ZEVA 1WY0A 5EATA 5DHIA 3WE9A 3N46F 3TFPA 4EA2A 1UBVA 1N1BA 1RTRA 4LIXA 4NFKF 3LSNA 3SDTA 2J5CA 1KIZA 4LZ0A 3AQBB 5B03A 2PS4A 4K10A 3RBMA 1YJ4A 1WL2A 2I19A 5ILJA 2Z4ZA 5JV1F 3OABB 4DHDA 3ID0A 2J1PA 2Z4YA 4LFGA 1FPSA 3SDUA 3WSBA 1UBWA 4NFIF 2Q58A 3LG5A 4GP1A 4OMHA 5H9DA 4MC3A 3EZ3A 3OACB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4LPH F;  5ILZ A;  3RYE A;  1UBX A;  4JXY A;  3QQV A;  5B02 A;  3ZCD A;  5A0I A;  5IMI A;  5A0K A;  3RMG A;  4KVI A;  3ICK A;  4JZX A;  2E8T A;  4N1Z F;  4KK2 A;  4LUU A;  4MC0 A;  3WEG A;  4LTV A;  3SDQ A;  3LMD A;  5EAU A;  4DZW A;  4KVD A;  4RXE A;  3KRA B;  5ILI A;  4KQU A;  1VG6 A;  3IPI A;  3P41 A;  2AET A;  2F8Z F;  5ILD A;  1YHK A;  4H5D F;  3WEH A;  4NFJ F;  4LLS A;  1WMW A;  3WJO A;  3P8L A;  3P5R A;  4WK5 A;  5IK6 A;  5B0J A;  5IN8 A;  4RNQ A;  3CC9 A;  4GA3 A;  3KRA A;  5IMP A;  4JZB A;  3Q2Z A;  4NKF A;  3P5P A;  4NUA A;  3OYR A;  5I1U A;  5JV2 F;  3ZMC A;  3NPR A;  1JFA A;  3APZ A;  3Q2Q A;  4KQ5 A;  5E8L A;  3UCA A;  4F6V A;  4MC8 A;  4XQR F;  1WL1 A;  5ERM A;  1YV5 A;  1EZF A;  2AEK A;  4DEM F;  2FTZ A;  3V66 A;  4OKM A;  4E9U A;  1DGP A;  2Z78 A;  4GP2 A;  3AQC B;  1N22 A;  5AFX A;  2F94 F;  3CP6 A;  3M01 A;  3WCB A;  3LLW A;  5IMN A;  4LPG F;  2EWG A;  1V4H A;  3KRF B;  1WKZ A;  3ADZ A;  4XQT F;  2RAH A;  5ERN A;  3SDR A;  2ZCR A;  5ILH A;  4P0W A;  2H8O A;  5B01 A;  4KWD A;  1ZW5 A;  5IL3 A;  4KUX A;  1V4E A;  4F6X A;  2DH4 A;  3TS7 A;  4KPJ A;  5IKA A;  3LEE A;  3DYG A;  1UBY A;  5JUZ F;  3MZV A;  3WC9 A;  3NPK A;  3LZ9 A;  2F89 F;  5ERO A;  4LXW A;  4QPF A;  5IK0 A;  3KRF A;  5ILY A;  4OGU A;  3VJ8 A;  3ICM A;  4KVW A;  3RYW A;  2PS5 A;  4OMG A;  2E8X A;  4RXA A;  1PS1 A;  2OGD A;  4F62 A;  3WCJ A;  2QIS A;  4E9Z A;  3WJN A;  2J1O A;  3KBK A;  2E94 A;  3Q1O A;  2OPM A;  3N0F A;  3WCL A;  4LA6 A;  2Z52 A;  4KPD A;  3OAB A;  1YHM A;  3AE0 A;  1HX9 A;  3N45 F;  3TC1 A;  4LLT A;  4DWB A;  5DGN F;  5A0J A;  2Z4V A;  4KQS A;  3WEI A;  1N20 A;  4H5C F;  3KB9 A;  5JV0 F;  4KVY A;  3OAC A;  5JA0 F;  5CG5 A;  3WCC A;  3Q30 A;  2AZJ A;  1V4I A;  5HN8 A;  3WCI A;  3N6K F;  3TFN A;  5EAS A;  2AEL A;  3WJK A;  4QXS F;  1HM4 A;  5E8H A;  4XQS F;  2ZY1 A;  3PYB A;  3S9V A;  1WL3 A;  5B0M A;  3WCE A;  3V1V A;  4PVY F;  4LFV F;  3S4J A;  3NRI A;  3SDV A;  3N3L F;  4DWG A;  4LOB A;  1HXG A;  3VJC A;  4N9U A;  1V4J A;  4E1E A;  3NF2 A;  5IK9 A;  1KIY A;  2VF6 A;  3KRO B;  3N3D A;  5IL8 A;  3G4F A;  5DJR F;  2Z7H A;  3PDE A;  1N1Z A;  1N24 A;  5HN9 A;  2E91 A;  3LGZ B;  4PVX F;  5KSX F;  2O1O A;  5DZ2 A;  3N0G A;  3TFV A;  3G4D A;  1VG3 A;  4RYP A;  2Z4W A;  2ZCO A;  3M9U A;  2Z7I A;  3LGK A;  3M0G A;  1N23 A;  4P0V A;  3VJA A;  3KRO A;  2Q80 A;  2PS6 A;  5B0I A;  2PS7 A;  4H5E F;  5AHU B;  3LVS A;  3WCF A;  2Z4X A;  3WSA A;  2ONH A;  2E8W A;  3ICN A;  5C05 A;  3CKE A;  3VJB A;  1RQJ A;  2P1C A;  4JVJ F;  5DJV F;  3ZMB A;  3WCH A;  5DIQ F;  3BNX A;  5IM1 A;  3ACX A;  3M02 A;  3LJI A;  3M00 A;  3DYH A;  5DGS F;  1YHL A;  1HM7 A;  5IKH A;  5E8K A;  1WL0 A;  3N1W F;  5B0K A;  4DI5 A;  5CG6 A;  3KRC B;  3ZL6 A;  2AZK A;  4LZC A;  3V1X A;  3EFQ A;  5DJP F;  4UMJ A;  2E95 A;  3IBA A;  2OA6 A;  3VJD A;  3N5H F;  4LTZ A;  3WCM A;  1YYQ A;  4EA0 A;  3W7F A;  3LOM A;  3N1V F;  5ER8 A;  1VG2 A;  3SAE A;  3WEJ A;  1YYR A;  3PYA A;  1JFG A;  2PS8 A;  3WEF A;  3KRC A;  3ACY A;  3P8R A;  3N49 F;  4P0X A;  4FJQ A;  5B0L A;  4LFE A;  3BNY A;  3WCA A;  4KKM A;  3PH7 A;  2F9K F;  5AYP A;  3KRP B;  1HXA A;  5HN7 A;  4KFA A;  5DHK A;  3N5J F;  3VJE A;  1YQ7 A;  3VJ9 A;  3AQ0 A;  5ILK A;  4GAX A;  2E4O A;  2E93 A;  1DI1 A;  2ZCS A;  3DYF A;  4NKE A;  3ACW A;  1YYT A;  4EA1 A;  4RXD A;  3KRP A;  3ICZ A;  1HXC A;  2F8C F;  3B7L A;  4JXN A;  1VG4 A;  2ONG A;  1RQI A;  3PKO A;  3ZOU A;  2E8U A;  5AEL A;  1YYS A;  1N21 A;  5IVG A;  3ASX A;  2ZCQ A;  4OKZ A;  4L2X F;  4JYX A;  3LDW A;  3WEK A;  5DW7 A;  3QKC A;  2OPN A;  5DGM F;  2E90 A;  2ZEU A;  2F7M F;  5HNA A;  3LK5 A;  1YYU A;  2FOR A;  2Z50 A;  2Q9Z A;  1VG7 A;  4LZ3 A;  1V4K A;  4LA5 A;  4RXC A;  3WCD A;  2F92 F;  2AZL A;  3WCG A;  4DXJ A;  2E8V A;  4HD1 A;  3MAV A;  2Q9Y A;  4FP4 A;  2E92 A;  5B00 A;  3EGT A;  4NG6 A;  4Q23 A;  4ZQ8 A;  2ZEV A;  1WY0 A;  5EAT A;  5DHI A;  3WE9 A;  3N46 F;  3TFP A;  4EA2 A;  1UBV A;  1N1B A;  1RTR A;  4LIX A;  4NFK F;  3LSN A;  3SDT A;  2J5C A;  1KIZ A;  4LZ0 A;  3AQB B;  5B03 A;  2PS4 A;  4K10 A;  3RBM A;  1YJ4 A;  1WL2 A;  2I19 A;  5ILJ A;  2Z4Z A;  5JV1 F;  3OAB B;  4DHD A;  3ID0 A;  2J1P A;  2Z4Y A;  4LFG A;  1FPS A;  3SDU A;  3WSB A;  1UBW A;  4NFI F;  2Q58 A;  3LG5 A;  4GP1 A;  4OMH A;  5H9D A;  4MC3 A;  3EZ3 A;  3OAC B; 
#chains in the Genus database with same CATH topology
 4LPH F;  5ILZ A;  3RYE A;  1UBX A;  4JXY A;  3QQV A;  5B02 A;  3ZCD A;  5A0I A;  5IMI A;  5A0K A;  3RMG A;  4KVI A;  3ICK A;  4JZX A;  2E8T A;  4N1Z F;  4KK2 A;  4LUU A;  4MC0 A;  3WEG A;  4LTV A;  3SDQ A;  3LMD A;  5EAU A;  4DZW A;  4KVD A;  4RXE A;  3KRA B;  5ILI A;  4KQU A;  1VG6 A;  3IPI A;  3P41 A;  2AET A;  2F8Z F;  5ILD A;  1YHK A;  4H5D F;  3WEH A;  4NFJ F;  4LLS A;  1WMW A;  3WJO A;  3P8L A;  3P5R A;  4WK5 A;  5IK6 A;  5B0J A;  5IN8 A;  4RNQ A;  3CC9 A;  4GA3 A;  3KRA A;  5IMP A;  4JZB A;  3Q2Z A;  4NKF A;  3P5P A;  4NUA A;  3OYR A;  5I1U A;  5JV2 F;  3ZMC A;  3NPR A;  1JFA A;  3APZ A;  3Q2Q A;  4KQ5 A;  5E8L A;  3UCA A;  4F6V A;  4MC8 A;  4XQR F;  1WL1 A;  5ERM A;  1YV5 A;  1EZF A;  2AEK A;  4DEM F;  2FTZ A;  3V66 A;  4OKM A;  4E9U A;  1DGP A;  2Z78 A;  4GP2 A;  3AQC B;  1N22 A;  5AFX A;  2F94 F;  3CP6 A;  3M01 A;  3WCB A;  3LLW A;  5IMN A;  4LPG F;  2EWG A;  1V4H A;  3KRF B;  1WKZ A;  3ADZ A;  4XQT F;  2RAH A;  5ERN A;  3SDR A;  2ZCR A;  5ILH A;  4P0W A;  2H8O A;  5B01 A;  4KWD A;  1ZW5 A;  5IL3 A;  4KUX A;  1V4E A;  4F6X A;  2DH4 A;  3TS7 A;  4KPJ A;  5IKA A;  3LEE A;  3DYG A;  1UBY A;  5JUZ F;  3MZV A;  3WC9 A;  3NPK A;  3LZ9 A;  2F89 F;  5ERO A;  4LXW A;  4QPF A;  5IK0 A;  3KRF A;  5ILY A;  4OGU A;  3VJ8 A;  3ICM A;  4KVW A;  3RYW A;  2PS5 A;  4OMG A;  2E8X A;  4RXA A;  1PS1 A;  2OGD A;  4F62 A;  3WCJ A;  2QIS A;  4E9Z A;  3WJN A;  2J1O A;  3KBK A;  2E94 A;  3Q1O A;  2OPM A;  3N0F A;  3WCL A;  4LA6 A;  2Z52 A;  4KPD A;  3OAB A;  1YHM A;  3AE0 A;  1HX9 A;  3N45 F;  3TC1 A;  4LLT A;  4DWB A;  5DGN F;  5A0J A;  2Z4V A;  4KQS A;  3WEI A;  1N20 A;  4H5C F;  3KB9 A;  5JV0 F;  4KVY A;  3OAC A;  5JA0 F;  5CG5 A;  3WCC A;  3Q30 A;  2AZJ A;  1V4I A;  5HN8 A;  3WCI A;  3N6K F;  3TFN A;  5EAS A;  2AEL A;  3WJK A;  4QXS F;  1HM4 A;  5E8H A;  4XQS F;  2ZY1 A;  3PYB A;  3S9V A;  1WL3 A;  5B0M A;  3WCE A;  3V1V A;  4PVY F;  4LFV F;  3S4J A;  3NRI A;  3SDV A;  3N3L F;  4DWG A;  4LOB A;  1HXG A;  3VJC A;  4N9U A;  1V4J A;  4E1E A;  3NF2 A;  5IK9 A;  1KIY A;  2VF6 A;  3KRO B;  3N3D A;  5IL8 A;  3G4F A;  5DJR F;  2Z7H A;  3PDE A;  1N1Z A;  1N24 A;  5HN9 A;  2E91 A;  3LGZ B;  4PVX F;  5KSX F;  2O1O A;  5DZ2 A;  3N0G A;  3TFV A;  3G4D A;  1VG3 A;  4RYP A;  2Z4W A;  2ZCO A;  3M9U A;  2Z7I A;  3LGK A;  3M0G A;  1N23 A;  4P0V A;  3VJA A;  3KRO A;  2Q80 A;  2PS6 A;  5B0I A;  2PS7 A;  4H5E F;  5AHU B;  3LVS A;  3WCF A;  2Z4X A;  3WSA A;  2ONH A;  2E8W A;  3ICN A;  5C05 A;  3CKE A;  3VJB A;  1RQJ A;  2P1C A;  4JVJ F;  5DJV F;  3ZMB A;  3WCH A;  5DIQ F;  3BNX A;  5IM1 A;  3ACX A;  3M02 A;  3LJI A;  3M00 A;  3DYH A;  5DGS F;  1YHL A;  1HM7 A;  5IKH A;  5E8K A;  1WL0 A;  3N1W F;  5B0K A;  4DI5 A;  5CG6 A;  3KRC B;  3ZL6 A;  2AZK A;  4LZC A;  3V1X A;  3EFQ A;  5DJP F;  4UMJ A;  2E95 A;  3IBA A;  2OA6 A;  3VJD A;  3N5H F;  4LTZ A;  3WCM A;  1YYQ A;  4EA0 A;  3W7F A;  3LOM A;  3N1V F;  5ER8 A;  1VG2 A;  3SAE A;  3WEJ A;  1YYR A;  3PYA A;  1JFG A;  2PS8 A;  3WEF A;  3KRC A;  3ACY A;  3P8R A;  3N49 F;  4P0X A;  4FJQ A;  5B0L A;  4LFE A;  3BNY A;  3WCA A;  4KKM A;  3PH7 A;  2F9K F;  5AYP A;  3KRP B;  1HXA A;  5HN7 A;  4KFA A;  5DHK A;  3N5J F;  3VJE A;  1YQ7 A;  3VJ9 A;  3AQ0 A;  5ILK A;  4GAX A;  2E4O A;  2E93 A;  1DI1 A;  2ZCS A;  3DYF A;  4NKE A;  3ACW A;  1YYT A;  4EA1 A;  4RXD A;  3KRP A;  3ICZ A;  1HXC A;  2F8C F;  3B7L A;  4JXN A;  1VG4 A;  2ONG A;  1RQI A;  3PKO A;  3ZOU A;  2E8U A;  5AEL A;  1YYS A;  1N21 A;  5IVG A;  3ASX A;  2ZCQ A;  4OKZ A;  4L2X F;  4JYX A;  3LDW A;  3WEK A;  5DW7 A;  3QKC A;  2OPN A;  5DGM F;  2E90 A;  2ZEU A;  2F7M F;  5HNA A;  3LK5 A;  1YYU A;  2FOR A;  2Z50 A;  2Q9Z A;  1VG7 A;  4LZ3 A;  1V4K A;  4LA5 A;  4RXC A;  3WCD A;  2F92 F;  2AZL A;  3WCG A;  4DXJ A;  2E8V A;  4HD1 A;  3MAV A;  2Q9Y A;  4FP4 A;  2E92 A;  5B00 A;  3EGT A;  4NG6 A;  4Q23 A;  4ZQ8 A;  2ZEV A;  1WY0 A;  5EAT A;  5DHI A;  3WE9 A;  3N46 F;  3TFP A;  4EA2 A;  1UBV A;  1N1B A;  1RTR A;  4LIX A;  4NFK F;  3LSN A;  3SDT A;  2J5C A;  1KIZ A;  4LZ0 A;  3AQB B;  5B03 A;  2PS4 A;  4K10 A;  3RBM A;  1YJ4 A;  1WL2 A;  2I19 A;  5ILJ A;  2Z4Z A;  5JV1 F;  3OAB B;  4DHD A;  3ID0 A;  2J1P A;  2Z4Y A;  4LFG A;  1FPS A;  3SDU A;  3WSB A;  1UBW A;  4NFI F;  2Q58 A;  3LG5 A;  4GP1 A;  4OMH A;  5H9D A;  4MC3 A;  3EZ3 A;  3OAC B; 
#chains in the Genus database with same CATH homology
 4LPH F;  5ILZ A;  3RYE A;  1UBX A;  4JXY A;  3QQV A;  5B02 A;  3ZCD A;  5A0I A;  5IMI A;  5A0K A;  3RMG A;  4KVI A;  3ICK A;  4JZX A;  2E8T A;  4N1Z F;  4KK2 A;  4LUU A;  4MC0 A;  3WEG A;  4LTV A;  3SDQ A;  3LMD A;  5EAU A;  4DZW A;  4KVD A;  4RXE A;  3KRA B;  5ILI A;  4KQU A;  1VG6 A;  3IPI A;  3P41 A;  2AET A;  2F8Z F;  5ILD A;  1YHK A;  4H5D F;  3WEH A;  4NFJ F;  4LLS A;  1WMW A;  3WJO A;  3P8L A;  3P5R A;  4WK5 A;  5IK6 A;  5B0J A;  5IN8 A;  4RNQ A;  3CC9 A;  4GA3 A;  3KRA A;  5IMP A;  4JZB A;  3Q2Z A;  4NKF A;  3P5P A;  4NUA A;  3OYR A;  5I1U A;  5JV2 F;  3ZMC A;  3NPR A;  1JFA A;  3APZ A;  3Q2Q A;  4KQ5 A;  5E8L A;  3UCA A;  4F6V A;  4MC8 A;  4XQR F;  1WL1 A;  5ERM A;  1YV5 A;  1EZF A;  2AEK A;  4DEM F;  2FTZ A;  3V66 A;  4OKM A;  4E9U A;  1DGP A;  2Z78 A;  4GP2 A;  3AQC B;  1N22 A;  5AFX A;  2F94 F;  3CP6 A;  3M01 A;  3WCB A;  3LLW A;  5IMN A;  4LPG F;  2EWG A;  1V4H A;  3KRF B;  1WKZ A;  3ADZ A;  4XQT F;  2RAH A;  5ERN A;  3SDR A;  2ZCR A;  5ILH A;  4P0W A;  2H8O A;  5B01 A;  4KWD A;  1ZW5 A;  5IL3 A;  4KUX A;  1V4E A;  4F6X A;  2DH4 A;  3TS7 A;  4KPJ A;  5IKA A;  3LEE A;  3DYG A;  1UBY A;  5JUZ F;  3MZV A;  3WC9 A;  3NPK A;  3LZ9 A;  2F89 F;  5ERO A;  4LXW A;  4QPF A;  5IK0 A;  3KRF A;  5ILY A;  4OGU A;  3VJ8 A;  3ICM A;  4KVW A;  3RYW A;  2PS5 A;  4OMG A;  2E8X A;  4RXA A;  1PS1 A;  2OGD A;  4F62 A;  3WCJ A;  2QIS A;  4E9Z A;  3WJN A;  2J1O A;  3KBK A;  2E94 A;  3Q1O A;  2OPM A;  3N0F A;  3WCL A;  4LA6 A;  2Z52 A;  4KPD A;  3OAB A;  1YHM A;  3AE0 A;  1HX9 A;  3N45 F;  3TC1 A;  4LLT A;  4DWB A;  5DGN F;  5A0J A;  2Z4V A;  4KQS A;  3WEI A;  1N20 A;  4H5C F;  3KB9 A;  5JV0 F;  4KVY A;  3OAC A;  5JA0 F;  5CG5 A;  3WCC A;  3Q30 A;  2AZJ A;  1V4I A;  5HN8 A;  3WCI A;  3N6K F;  3TFN A;  5EAS A;  2AEL A;  3WJK A;  4QXS F;  1HM4 A;  5E8H A;  4XQS F;  2ZY1 A;  3PYB A;  3S9V A;  1WL3 A;  5B0M A;  3WCE A;  3V1V A;  4PVY F;  4LFV F;  3S4J A;  3NRI A;  3SDV A;  3N3L F;  4DWG A;  4LOB A;  1HXG A;  3VJC A;  4N9U A;  1V4J A;  4E1E A;  3NF2 A;  5IK9 A;  1KIY A;  2VF6 A;  3KRO B;  3N3D A;  5IL8 A;  3G4F A;  5DJR F;  2Z7H A;  3PDE A;  1N1Z A;  1N24 A;  5HN9 A;  2E91 A;  3LGZ B;  4PVX F;  5KSX F;  2O1O A;  5DZ2 A;  3N0G A;  3TFV A;  3G4D A;  1VG3 A;  4RYP A;  2Z4W A;  2ZCO A;  3M9U A;  2Z7I A;  3LGK A;  3M0G A;  1N23 A;  4P0V A;  3VJA A;  3KRO A;  2Q80 A;  2PS6 A;  5B0I A;  2PS7 A;  4H5E F;  5AHU B;  3LVS A;  3WCF A;  2Z4X A;  3WSA A;  2ONH A;  2E8W A;  3ICN A;  5C05 A;  3CKE A;  3VJB A;  1RQJ A;  2P1C A;  4JVJ F;  5DJV F;  3ZMB A;  3WCH A;  5DIQ F;  3BNX A;  5IM1 A;  3ACX A;  3M02 A;  3LJI A;  3M00 A;  3DYH A;  5DGS F;  1YHL A;  1HM7 A;  5IKH A;  5E8K A;  1WL0 A;  3N1W F;  5B0K A;  4DI5 A;  5CG6 A;  3KRC B;  3ZL6 A;  2AZK A;  4LZC A;  3V1X A;  3EFQ A;  5DJP F;  4UMJ A;  2E95 A;  3IBA A;  2OA6 A;  3VJD A;  3N5H F;  4LTZ A;  3WCM A;  1YYQ A;  4EA0 A;  3W7F A;  3LOM A;  3N1V F;  5ER8 A;  1VG2 A;  3SAE A;  3WEJ A;  1YYR A;  3PYA A;  1JFG A;  2PS8 A;  3WEF A;  3KRC A;  3ACY A;  3P8R A;  3N49 F;  4P0X A;  4FJQ A;  5B0L A;  4LFE A;  3BNY A;  3WCA A;  4KKM A;  3PH7 A;  2F9K F;  5AYP A;  3KRP B;  1HXA A;  5HN7 A;  4KFA A;  5DHK A;  3N5J F;  3VJE A;  1YQ7 A;  3VJ9 A;  3AQ0 A;  5ILK A;  4GAX A;  2E4O A;  2E93 A;  1DI1 A;  2ZCS A;  3DYF A;  4NKE A;  3ACW A;  1YYT A;  4EA1 A;  4RXD A;  3KRP A;  3ICZ A;  1HXC A;  2F8C F;  3B7L A;  4JXN A;  1VG4 A;  2ONG A;  1RQI A;  3PKO A;  3ZOU A;  2E8U A;  5AEL A;  1YYS A;  1N21 A;  5IVG A;  3ASX A;  2ZCQ A;  4OKZ A;  4L2X F;  4JYX A;  3LDW A;  3WEK A;  5DW7 A;  3QKC A;  2OPN A;  5DGM F;  2E90 A;  2ZEU A;  2F7M F;  5HNA A;  3LK5 A;  1YYU A;  2FOR A;  2Z50 A;  2Q9Z A;  1VG7 A;  4LZ3 A;  1V4K A;  4LA5 A;  4RXC A;  3WCD A;  2F92 F;  2AZL A;  3WCG A;  4DXJ A;  2E8V A;  4HD1 A;  3MAV A;  2Q9Y A;  4FP4 A;  2E92 A;  5B00 A;  3EGT A;  4NG6 A;  4Q23 A;  4ZQ8 A;  2ZEV A;  1WY0 A;  5EAT A;  5DHI A;  3WE9 A;  3N46 F;  3TFP A;  4EA2 A;  1UBV A;  1N1B A;  1RTR A;  4LIX A;  4NFK F;  3LSN A;  3SDT A;  2J5C A;  1KIZ A;  4LZ0 A;  3AQB B;  5B03 A;  2PS4 A;  4K10 A;  3RBM A;  1YJ4 A;  1WL2 A;  2I19 A;  5ILJ A;  2Z4Z A;  5JV1 F;  3OAB B;  4DHD A;  3ID0 A;  2J1P A;  2Z4Y A;  4LFG A;  1FPS A;  3SDU A;  3WSB A;  1UBW A;  4NFI F;  2Q58 A;  3LG5 A;  4GP1 A;  4OMH A;  5H9D A;  4MC3 A;  3EZ3 A;  3OAC B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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