4KVIA

Crystal structure of aspergillus terreus aristolochene synthase complexed with (4as,7s)-4a-methyl-7-(prop-1-en-2-yl)-2,3,4,4a,5,6,7,8-octahydroquinolin-1-ium
Total Genus 133
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
133
sequence length
304
structure length
304
Chain Sequence
LEPPPSTFQPLCHPLVEEVSKEVDGYFLQHWNFPNEKARKKFVAAGFSRVTCLYFPKALDDRIHFACRLLTVLFLIDDLLEYMSFEEGSAYNEKLIPISRGDVLPDRSIPVEYIIYDLWESMRAHDREMADEILEPVFLFMRAQTDRTRARPMGLGGYLEYRERDVGKELLAALMRFSMGLKLSPSELQRVREIDANCSKHLSVVNDIYSYEKELYTSKTAHSEGGILCTSVQILAQEADVTAEAAKRVLFVMCREWELRHQLLVARLSAEGLETPGLAAYVEGLEYQMSGNELWSQTTLRYSV
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Mechanistic insights from the binding of substrate and carbocation intermediate analogues to aristolochene synthase.
pubmed doi rcsb
molecule tags Lyase/lyase inhibitor
source organism Aspergillus terreus
molecule keywords Aristolochene synthase
total genus 133
structure length 304
sequence length 304
chains with identical sequence B, C, D
ec nomenclature ec 4.2.3.9: Aristolochene synthase.
pdb deposition date 2013-05-22
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.600.10 Mainly Alpha Orthogonal Bundle Farnesyl Diphosphate Synthase Farnesyl Diphosphate Synthase 4kviA00
2ZCQA 4OMGA 3M02A 3M9UA 4N9UA 5AELA 3KROB 3LG5A 4LA6A 4KVDA 4NFJF 5B0JA 4OKZA 5A0JA 3ID0A 5EAUA 1YJ4A 1KIZA 4LXWA 3PDEA 5IMNA 5IK6A 2Z4ZA 3V66A 1YHLA 2E8XA 3BNXA 2Z4YA 2AZJA 3WEIA 3OABA 3P5RA 1YYUA 2VF6A 3WJNA 5EROA 4RXEA 3AQBB 3LEEA 3G4FA 4GP1A 3WEKA 2OA6A 4RYPA 3KBKA 1YYSA 2PS6A 3N5JF 5DGSF 3SAEA 3ICNA 4MC0A 2F94F 4LFVF 3IPIA 5DHKA 2O1OA 1PS1A 1N1ZA 5AHUB 5ILZA 3VJ8A 2ONGA 3KRPA 1EZFA 2PS7A 2E92A 5HN9A 4E1EA 4KQSA 3PYBA 1YQ7A 4LTVA 3LGKA 3WCCA 4RNQA 3AE0A 1VG2A 4LPGF 4LTZA 3CKEA 3KRCA 5HNAA 5HN8A 4ZQ8A 2Z78A 5AFXA 3RYEA 1JFGA 2E90A 5JA0F 5DGMF 2E8VA 4MC8A 3P41A 4GAXA 3WCBA 3WCGA 3V1XA 1UBYA 3LGZB 3KROA 4JVJF 1ZW5A 5IVGA 4LZ0A 3UCAA 1HXAA 3W7FA 3NPKA 5DIQF 4KFAA 3Q2ZA 4DXJA 3WSBA 5HN7A 3S9VA 3N49F 3TC1A 1N20A 2ZCSA 5B0LA 3AQCB 3P5PA 2E8TA 3BNYA 2Q58A 3ACYA 2Z4XA 5CG5A 4L2XF 4RXDA 3G4DA 2F92F 4DZWA 5ILIA 1YHMA 2P1CA 3LK5A 5DHIA 2F8CF 3Q1OA 3TS7A 3KRAB 4DI5A 5B0IA 2J5CA 3WEJA 1YHKA 2Z7IA 2AZKA 1N23A 3ZMBA 5ILKA 5ERNA 2ONHA 3S4JA 2FTZA 1VG4A 4EA1A 4DEMF 1DGPA 3APZA 1FPSA 5B0KA 3WC9A 4OMHA 3NF2A 3CP6A 3LZ9A 3VJDA 2J1OA 4E9ZA 5KSXF 2F9KF 1WL0A 3N3LF 3KRFB 2Z4WA 2Z4VA 4LZCA 3ACXA 3N1WF 4LZ3A 3SDRA 2OPMA 5EASA 2EWGA 3QKCA 3LJIA 4JYXA 2F7MF 3ZMCA 1N21A 3WJOA 4K10A 4P0WA 1HXCA 4F6XA 3WEGA 4RXCA 3WSAA 1VG6A 1UBXA 1YYTA 4PVXF 1UBVA 5ILYA 1HXGA 2ZEVA 5DJRF 5IK9A 5C05A 2E8WA 4Q23A 1RQJA 3KB9A 3DYFA 5ERMA 3ICKA 4XQTF 3SDVA 2PS5A 1VG7A 3LMDA 4KPDA 2QISA 3KRAA 3VJCA 1HX9A 4JXYA 3N0GA 2ZEUA 1WL1A 3LLWA 1YYRA 3N45F 3P8RA 2AELA 4GP2A 4LUUA 5E8HA 2ZCRA 3VJEA 4FJQA 4LA5A 3ASXA 2E91A 5EATA 3N3DA 4N1ZF 3ZOUA 5CG6A 1YV5A 2E94A 5B01A 4KWDA 4P0XA 1YYQA 3RBMA 5IN8A 3Q2QA 4LFGA 2J1PA 4H5EF 3KRFA 5IL8A 4KK2A 5E8LA 3N6KF 2Q80A 4JXNA 3KRPB 5I1UA 1JFAA 5DJPF 2RAHA 1V4IA 4H5CF 4HD1A 5B02A 2I19A 2AEKA 2PS4A 1V4JA 4NFIF 3M01A 5IMIA 5AYPA 5B0MA 3ADZA 3WCAA 3DYHA 5A0KA 5DZ2A 3OYRA 2ZCOA 3LVSA 4NG6A 4UMJA 4MC3A 2AZLA 2AETA 1V4EA 2Z50A 3N1VF 1KIYA 3LSNA 3VJBA 5DJVF 1V4HA 3MZVA 4OGUA 3WCDA 1V4KA 3ICZA 5IK0A 3LOMA 3OACB 3QQVA 4KQUA 5DW7A 1N24A 2PS8A 1HM4A 4LFEA 1WL2A 5B00A 4QXSF 3PH7A 3SDQA 3NPRA 1HM7A 3SDUA 3PYAA 3WCFA 4H5DF 4XQSF 3ZCDA 4PVYF 3TFVA 1WY0A 1N22A 2FORA 2DH4A 3TFPA 2Z52A 3RYWA 3WCMA 5IKAA 4LIXA 3ACWA 4DWGA 4DHDA 3N5HF 5IL3A 4NKEA 3SDTA 3MAVA 3ZL6A 5ILDA 2Q9ZA 4KQ5A 4NFKF 3WCIA 3WCHA 4KVWA 4LOBA 3IBAA 3N0FA 2OPNA 4LLSA 3WCJA 4LPHF 1WMWA 1RTRA 1RQIA 4GA3A 1VG3A 3EZ3A 4WK5A 4FP4A 1WL3A 3M0GA 4P0VA 4KVIA 3OABB 4JZXA 5DGNF 3DYGA 3ICMA 1N1BA 4XQRF 3WEFA 5JUZF 5JV1F 3CC9A 4NUAA 4RXAA 5IKHA 3LDWA 2E4OA 2Q9YA 4F6VA 2F89F 4EA2A 3OACA 4OKMA 3VJ9A 3N46F 1UBWA 5ILJA 3AQ0A 5E8KA 4KKMA 4KPJA 2ZY1A 4NKFA 5B03A 5ILHA 3RMGA 2OGDA 2E95A 5JV0F 3EGTA 4JZBA 5IMPA 4KVYA 3WE9A 3WEHA 3VJAA 3WJKA 5IM1A 3PKOA 4E9UA 2E8UA 4KUXA 4LLTA 2Z7HA 3M00A 1DI1A 3B7LA 3P8LA 3EFQA 5H9DA 3WCLA 3KRCB 3V1VA 3TFNA 4EA0A 3Q30A 4DWBA 5JV2F 2F8ZF 2E93A 5A0IA 1WKZA 4F62A 3WCEA 3NRIA 2H8OA 4QPFA 5ER8A
chains in the Genus database with same CATH superfamily
2ZCQA 4OMGA 3M02A 3M9UA 4N9UA 5AELA 3KROB 3LG5A 4LA6A 4KVDA 4NFJF 5B0JA 4OKZA 5A0JA 3ID0A 5EAUA 1YJ4A 1KIZA 4LXWA 3PDEA 5IMNA 5IK6A 2Z4ZA 3V66A 1YHLA 2E8XA 3BNXA 2Z4YA 2AZJA 3WEIA 3OABA 3P5RA 1YYUA 2VF6A 3WJNA 5EROA 4RXEA 3AQBB 3LEEA 3G4FA 4GP1A 3WEKA 2OA6A 4RYPA 3KBKA 1YYSA 2PS6A 3N5JF 5DGSF 3SAEA 3ICNA 4MC0A 2F94F 4LFVF 3IPIA 5DHKA 2O1OA 1PS1A 1N1ZA 5AHUB 5ILZA 3VJ8A 2ONGA 3KRPA 1EZFA 2PS7A 2E92A 5HN9A 4E1EA 4KQSA 3PYBA 1YQ7A 4LTVA 3LGKA 3WCCA 4RNQA 3AE0A 1VG2A 4LPGF 4LTZA 3CKEA 3KRCA 5HNAA 5HN8A 4ZQ8A 2Z78A 5AFXA 3RYEA 1JFGA 2E90A 5JA0F 5DGMF 2E8VA 4MC8A 3P41A 4GAXA 3WCBA 3WCGA 3V1XA 1UBYA 3LGZB 3KROA 4JVJF 1ZW5A 5IVGA 4LZ0A 3UCAA 1HXAA 3W7FA 3NPKA 5DIQF 4KFAA 3Q2ZA 4DXJA 3WSBA 5HN7A 3S9VA 3N49F 3TC1A 1N20A 2ZCSA 5B0LA 3AQCB 3P5PA 2E8TA 3BNYA 2Q58A 3ACYA 2Z4XA 5CG5A 4L2XF 4RXDA 3G4DA 2F92F 4DZWA 5ILIA 1YHMA 2P1CA 3LK5A 5DHIA 2F8CF 3Q1OA 3TS7A 3KRAB 4DI5A 5B0IA 2J5CA 3WEJA 1YHKA 2Z7IA 2AZKA 1N23A 3ZMBA 5ILKA 5ERNA 2ONHA 3S4JA 2FTZA 1VG4A 4EA1A 4DEMF 1DGPA 3APZA 1FPSA 5B0KA 3WC9A 4OMHA 3NF2A 3CP6A 3LZ9A 3VJDA 2J1OA 4E9ZA 5KSXF 2F9KF 1WL0A 3N3LF 3KRFB 2Z4WA 2Z4VA 4LZCA 3ACXA 3N1WF 4LZ3A 3SDRA 2OPMA 5EASA 2EWGA 3QKCA 3LJIA 4JYXA 2F7MF 3ZMCA 1N21A 3WJOA 4K10A 4P0WA 1HXCA 4F6XA 3WEGA 4RXCA 3WSAA 1VG6A 1UBXA 1YYTA 4PVXF 1UBVA 5ILYA 1HXGA 2ZEVA 5DJRF 5IK9A 5C05A 2E8WA 4Q23A 1RQJA 3KB9A 3DYFA 5ERMA 3ICKA 4XQTF 3SDVA 2PS5A 1VG7A 3LMDA 4KPDA 2QISA 3KRAA 3VJCA 1HX9A 4JXYA 3N0GA 2ZEUA 1WL1A 3LLWA 1YYRA 3N45F 3P8RA 2AELA 4GP2A 4LUUA 5E8HA 2ZCRA 3VJEA 4FJQA 4LA5A 3ASXA 2E91A 5EATA 3N3DA 4N1ZF 3ZOUA 5CG6A 1YV5A 2E94A 5B01A 4KWDA 4P0XA 1YYQA 3RBMA 5IN8A 3Q2QA 4LFGA 2J1PA 4H5EF 3KRFA 5IL8A 4KK2A 5E8LA 3N6KF 2Q80A 4JXNA 3KRPB 5I1UA 1JFAA 5DJPF 2RAHA 1V4IA 4H5CF 4HD1A 5B02A 2I19A 2AEKA 2PS4A 1V4JA 4NFIF 3M01A 5IMIA 5AYPA 5B0MA 3ADZA 3WCAA 3DYHA 5A0KA 5DZ2A 3OYRA 2ZCOA 3LVSA 4NG6A 4UMJA 4MC3A 2AZLA 2AETA 1V4EA 2Z50A 3N1VF 1KIYA 3LSNA 3VJBA 5DJVF 1V4HA 3MZVA 4OGUA 3WCDA 1V4KA 3ICZA 5IK0A 3LOMA 3OACB 3QQVA 4KQUA 5DW7A 1N24A 2PS8A 1HM4A 4LFEA 1WL2A 5B00A 4QXSF 3PH7A 3SDQA 3NPRA 1HM7A 3SDUA 3PYAA 3WCFA 4H5DF 4XQSF 3ZCDA 4PVYF 3TFVA 1WY0A 1N22A 2FORA 2DH4A 3TFPA 2Z52A 3RYWA 3WCMA 5IKAA 4LIXA 3ACWA 4DWGA 4DHDA 3N5HF 5IL3A 4NKEA 3SDTA 3MAVA 3ZL6A 5ILDA 2Q9ZA 4KQ5A 4NFKF 3WCIA 3WCHA 4KVWA 4LOBA 3IBAA 3N0FA 2OPNA 4LLSA 3WCJA 4LPHF 1WMWA 1RTRA 1RQIA 4GA3A 1VG3A 3EZ3A 4WK5A 4FP4A 1WL3A 3M0GA 4P0VA 4KVIA 3OABB 4JZXA 5DGNF 3DYGA 3ICMA 1N1BA 4XQRF 3WEFA 5JUZF 5JV1F 3CC9A 4NUAA 4RXAA 5IKHA 3LDWA 2E4OA 2Q9YA 4F6VA 2F89F 4EA2A 3OACA 4OKMA 3VJ9A 3N46F 1UBWA 5ILJA 3AQ0A 5E8KA 4KKMA 4KPJA 2ZY1A 4NKFA 5B03A 5ILHA 3RMGA 2OGDA 2E95A 5JV0F 3EGTA 4JZBA 5IMPA 4KVYA 3WE9A 3WEHA 3VJAA 3WJKA 5IM1A 3PKOA 4E9UA 2E8UA 4KUXA 4LLTA 2Z7HA 3M00A 1DI1A 3B7LA 3P8LA 3EFQA 5H9DA 3WCLA 3KRCB 3V1VA 3TFNA 4EA0A 3Q30A 4DWBA 5JV2F 2F8ZF 2E93A 5A0IA 1WKZA 4F62A 3WCEA 3NRIA 2H8OA 4QPFA 5ER8A
chains in the Genus database with same CATH topology
2ZCQA 4OMGA 3M02A 3M9UA 4N9UA 5AELA 3KROB 3LG5A 4LA6A 4KVDA 4NFJF 5B0JA 4OKZA 5A0JA 3ID0A 5EAUA 1YJ4A 1KIZA 4LXWA 3PDEA 5IMNA 5IK6A 2Z4ZA 3V66A 1YHLA 2E8XA 3BNXA 2Z4YA 2AZJA 3WEIA 3OABA 3P5RA 1YYUA 2VF6A 3WJNA 5EROA 4RXEA 3AQBB 3LEEA 3G4FA 4GP1A 3WEKA 2OA6A 4RYPA 3KBKA 1YYSA 2PS6A 3N5JF 5DGSF 3SAEA 3ICNA 4MC0A 2F94F 4LFVF 3IPIA 5DHKA 2O1OA 1PS1A 1N1ZA 5AHUB 5ILZA 3VJ8A 2ONGA 3KRPA 1EZFA 2PS7A 2E92A 5HN9A 4E1EA 4KQSA 3PYBA 1YQ7A 4LTVA 3LGKA 3WCCA 4RNQA 3AE0A 1VG2A 4LPGF 4LTZA 3CKEA 3KRCA 5HNAA 5HN8A 4ZQ8A 2Z78A 5AFXA 3RYEA 1JFGA 2E90A 5JA0F 5DGMF 2E8VA 4MC8A 3P41A 4GAXA 3WCBA 3WCGA 3V1XA 1UBYA 3LGZB 3KROA 4JVJF 1ZW5A 5IVGA 4LZ0A 3UCAA 1HXAA 3W7FA 3NPKA 5DIQF 4KFAA 3Q2ZA 4DXJA 3WSBA 5HN7A 3S9VA 3N49F 3TC1A 1N20A 2ZCSA 5B0LA 3AQCB 3P5PA 2E8TA 3BNYA 2Q58A 3ACYA 2Z4XA 5CG5A 4L2XF 4RXDA 3G4DA 2F92F 4DZWA 5ILIA 1YHMA 2P1CA 3LK5A 5DHIA 2F8CF 3Q1OA 3TS7A 3KRAB 4DI5A 5B0IA 2J5CA 3WEJA 1YHKA 2Z7IA 2AZKA 1N23A 3ZMBA 5ILKA 5ERNA 2ONHA 3S4JA 2FTZA 1VG4A 4EA1A 4DEMF 1DGPA 3APZA 1FPSA 5B0KA 3WC9A 4OMHA 3NF2A 3CP6A 3LZ9A 3VJDA 2J1OA 4E9ZA 5KSXF 2F9KF 1WL0A 3N3LF 3KRFB 2Z4WA 2Z4VA 4LZCA 3ACXA 3N1WF 4LZ3A 3SDRA 2OPMA 5EASA 2EWGA 3QKCA 3LJIA 4JYXA 2F7MF 3ZMCA 1N21A 3WJOA 4K10A 4P0WA 1HXCA 4F6XA 3WEGA 4RXCA 3WSAA 1VG6A 1UBXA 1YYTA 4PVXF 1UBVA 5ILYA 1HXGA 2ZEVA 5DJRF 5IK9A 5C05A 2E8WA 4Q23A 1RQJA 3KB9A 3DYFA 5ERMA 3ICKA 4XQTF 3SDVA 2PS5A 1VG7A 3LMDA 4KPDA 2QISA 3KRAA 3VJCA 1HX9A 4JXYA 3N0GA 2ZEUA 1WL1A 3LLWA 1YYRA 3N45F 3P8RA 2AELA 4GP2A 4LUUA 5E8HA 2ZCRA 3VJEA 4FJQA 4LA5A 3ASXA 2E91A 5EATA 3N3DA 4N1ZF 3ZOUA 5CG6A 1YV5A 2E94A 5B01A 4KWDA 4P0XA 1YYQA 3RBMA 5IN8A 3Q2QA 4LFGA 2J1PA 4H5EF 3KRFA 5IL8A 4KK2A 5E8LA 3N6KF 2Q80A 4JXNA 3KRPB 5I1UA 1JFAA 5DJPF 2RAHA 1V4IA 4H5CF 4HD1A 5B02A 2I19A 2AEKA 2PS4A 1V4JA 4NFIF 3M01A 5IMIA 5AYPA 5B0MA 3ADZA 3WCAA 3DYHA 5A0KA 5DZ2A 3OYRA 2ZCOA 3LVSA 4NG6A 4UMJA 4MC3A 2AZLA 2AETA 1V4EA 2Z50A 3N1VF 1KIYA 3LSNA 3VJBA 5DJVF 1V4HA 3MZVA 4OGUA 3WCDA 1V4KA 3ICZA 5IK0A 3LOMA 3OACB 3QQVA 4KQUA 5DW7A 1N24A 2PS8A 1HM4A 4LFEA 1WL2A 5B00A 4QXSF 3PH7A 3SDQA 3NPRA 1HM7A 3SDUA 3PYAA 3WCFA 4H5DF 4XQSF 3ZCDA 4PVYF 3TFVA 1WY0A 1N22A 2FORA 2DH4A 3TFPA 2Z52A 3RYWA 3WCMA 5IKAA 4LIXA 3ACWA 4DWGA 4DHDA 3N5HF 5IL3A 4NKEA 3SDTA 3MAVA 3ZL6A 5ILDA 2Q9ZA 4KQ5A 4NFKF 3WCIA 3WCHA 4KVWA 4LOBA 3IBAA 3N0FA 2OPNA 4LLSA 3WCJA 4LPHF 1WMWA 1RTRA 1RQIA 4GA3A 1VG3A 3EZ3A 4WK5A 4FP4A 1WL3A 3M0GA 4P0VA 4KVIA 3OABB 4JZXA 5DGNF 3DYGA 3ICMA 1N1BA 4XQRF 3WEFA 5JUZF 5JV1F 3CC9A 4NUAA 4RXAA 5IKHA 3LDWA 2E4OA 2Q9YA 4F6VA 2F89F 4EA2A 3OACA 4OKMA 3VJ9A 3N46F 1UBWA 5ILJA 3AQ0A 5E8KA 4KKMA 4KPJA 2ZY1A 4NKFA 5B03A 5ILHA 3RMGA 2OGDA 2E95A 5JV0F 3EGTA 4JZBA 5IMPA 4KVYA 3WE9A 3WEHA 3VJAA 3WJKA 5IM1A 3PKOA 4E9UA 2E8UA 4KUXA 4LLTA 2Z7HA 3M00A 1DI1A 3B7LA 3P8LA 3EFQA 5H9DA 3WCLA 3KRCB 3V1VA 3TFNA 4EA0A 3Q30A 4DWBA 5JV2F 2F8ZF 2E93A 5A0IA 1WKZA 4F62A 3WCEA 3NRIA 2H8OA 4QPFA 5ER8A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2ZCQ A;  4OMG A;  3M02 A;  3M9U A;  4N9U A;  5AEL A;  3KRO B;  3LG5 A;  4LA6 A;  4KVD A;  4NFJ F;  5B0J A;  4OKZ A;  5A0J A;  3ID0 A;  5EAU A;  1YJ4 A;  1KIZ A;  4LXW A;  3PDE A;  5IMN A;  5IK6 A;  2Z4Z A;  3V66 A;  1YHL A;  2E8X A;  3BNX A;  2Z4Y A;  2AZJ A;  3WEI A;  3OAB A;  3P5R A;  1YYU A;  2VF6 A;  3WJN A;  5ERO A;  4RXE A;  3AQB B;  3LEE A;  3G4F A;  4GP1 A;  3WEK A;  2OA6 A;  4RYP A;  3KBK A;  1YYS A;  2PS6 A;  3N5J F;  5DGS F;  3SAE A;  3ICN A;  4MC0 A;  2F94 F;  4LFV F;  3IPI A;  5DHK A;  2O1O A;  1PS1 A;  1N1Z A;  5AHU B;  5ILZ A;  3VJ8 A;  2ONG A;  3KRP A;  1EZF A;  2PS7 A;  2E92 A;  5HN9 A;  4E1E A;  4KQS A;  3PYB A;  1YQ7 A;  4LTV A;  3LGK A;  3WCC A;  4RNQ A;  3AE0 A;  1VG2 A;  4LPG F;  4LTZ A;  3CKE A;  3KRC A;  5HNA A;  5HN8 A;  4ZQ8 A;  2Z78 A;  5AFX A;  3RYE A;  1JFG A;  2E90 A;  5JA0 F;  5DGM F;  2E8V A;  4MC8 A;  3P41 A;  4GAX A;  3WCB A;  3WCG A;  3V1X A;  1UBY A;  3LGZ B;  3KRO A;  4JVJ F;  1ZW5 A;  5IVG A;  4LZ0 A;  3UCA A;  1HXA A;  3W7F A;  3NPK A;  5DIQ F;  4KFA A;  3Q2Z A;  4DXJ A;  3WSB A;  5HN7 A;  3S9V A;  3N49 F;  3TC1 A;  1N20 A;  2ZCS A;  5B0L A;  3AQC B;  3P5P A;  2E8T A;  3BNY A;  2Q58 A;  3ACY A;  2Z4X A;  5CG5 A;  4L2X F;  4RXD A;  3G4D A;  2F92 F;  4DZW A;  5ILI A;  1YHM A;  2P1C A;  3LK5 A;  5DHI A;  2F8C F;  3Q1O A;  3TS7 A;  3KRA B;  4DI5 A;  5B0I A;  2J5C A;  3WEJ A;  1YHK A;  2Z7I A;  2AZK A;  1N23 A;  3ZMB A;  5ILK A;  5ERN A;  2ONH A;  3S4J A;  2FTZ A;  1VG4 A;  4EA1 A;  4DEM F;  1DGP A;  3APZ A;  1FPS A;  5B0K A;  3WC9 A;  4OMH A;  3NF2 A;  3CP6 A;  3LZ9 A;  3VJD A;  2J1O A;  4E9Z A;  5KSX F;  2F9K F;  1WL0 A;  3N3L F;  3KRF B;  2Z4W A;  2Z4V A;  4LZC A;  3ACX A;  3N1W F;  4LZ3 A;  3SDR A;  2OPM A;  5EAS A;  2EWG A;  3QKC A;  3LJI A;  4JYX A;  2F7M F;  3ZMC A;  1N21 A;  3WJO A;  4K10 A;  4P0W A;  1HXC A;  4F6X A;  3WEG A;  4RXC A;  3WSA A;  1VG6 A;  1UBX A;  1YYT A;  4PVX F;  1UBV A;  5ILY A;  1HXG A;  2ZEV A;  5DJR F;  5IK9 A;  5C05 A;  2E8W A;  4Q23 A;  1RQJ A;  3KB9 A;  3DYF A;  5ERM A;  3ICK A;  4XQT F;  3SDV A;  2PS5 A;  1VG7 A;  3LMD A;  4KPD A;  2QIS A;  3KRA A;  3VJC A;  1HX9 A;  4JXY A;  3N0G A;  2ZEU A;  1WL1 A;  3LLW A;  1YYR A;  3N45 F;  3P8R A;  2AEL A;  4GP2 A;  4LUU A;  5E8H A;  2ZCR A;  3VJE A;  4FJQ A;  4LA5 A;  3ASX A;  2E91 A;  5EAT A;  3N3D A;  4N1Z F;  3ZOU A;  5CG6 A;  1YV5 A;  2E94 A;  5B01 A;  4KWD A;  4P0X A;  1YYQ A;  3RBM A;  5IN8 A;  3Q2Q A;  4LFG A;  2J1P A;  4H5E F;  3KRF A;  5IL8 A;  4KK2 A;  5E8L A;  3N6K F;  2Q80 A;  4JXN A;  3KRP B;  5I1U A;  1JFA A;  5DJP F;  2RAH A;  1V4I A;  4H5C F;  4HD1 A;  5B02 A;  2I19 A;  2AEK A;  2PS4 A;  1V4J A;  4NFI F;  3M01 A;  5IMI A;  5AYP A;  5B0M A;  3ADZ A;  3WCA A;  3DYH A;  5A0K A;  5DZ2 A;  3OYR A;  2ZCO A;  3LVS A;  4NG6 A;  4UMJ A;  4MC3 A;  2AZL A;  2AET A;  1V4E A;  2Z50 A;  3N1V F;  1KIY A;  3LSN A;  3VJB A;  5DJV F;  1V4H A;  3MZV A;  4OGU A;  3WCD A;  1V4K A;  3ICZ A;  5IK0 A;  3LOM A;  3OAC B;  3QQV A;  4KQU A;  5DW7 A;  1N24 A;  2PS8 A;  1HM4 A;  4LFE A;  1WL2 A;  5B00 A;  4QXS F;  3PH7 A;  3SDQ A;  3NPR A;  1HM7 A;  3SDU A;  3PYA A;  3WCF A;  4H5D F;  4XQS F;  3ZCD A;  4PVY F;  3TFV A;  1WY0 A;  1N22 A;  2FOR A;  2DH4 A;  3TFP A;  2Z52 A;  3RYW A;  3WCM A;  5IKA A;  4LIX A;  3ACW A;  4DWG A;  4DHD A;  3N5H F;  5IL3 A;  4NKE A;  3SDT A;  3MAV A;  3ZL6 A;  5ILD A;  2Q9Z A;  4KQ5 A;  4NFK F;  3WCI A;  3WCH A;  4KVW A;  4LOB A;  3IBA A;  3N0F A;  2OPN A;  4LLS A;  3WCJ A;  4LPH F;  1WMW A;  1RTR A;  1RQI A;  4GA3 A;  1VG3 A;  3EZ3 A;  4WK5 A;  4FP4 A;  1WL3 A;  3M0G A;  4P0V A;  4KVI A;  3OAB B;  4JZX A;  5DGN F;  3DYG A;  3ICM A;  1N1B A;  4XQR F;  3WEF A;  5JUZ F;  5JV1 F;  3CC9 A;  4NUA A;  4RXA A;  5IKH A;  3LDW A;  2E4O A;  2Q9Y A;  4F6V A;  2F89 F;  4EA2 A;  3OAC A;  4OKM A;  3VJ9 A;  3N46 F;  1UBW A;  5ILJ A;  3AQ0 A;  5E8K A;  4KKM A;  4KPJ A;  2ZY1 A;  4NKF A;  5B03 A;  5ILH A;  3RMG A;  2OGD A;  2E95 A;  5JV0 F;  3EGT A;  4JZB A;  5IMP A;  4KVY A;  3WE9 A;  3WEH A;  3VJA A;  3WJK A;  5IM1 A;  3PKO A;  4E9U A;  2E8U A;  4KUX A;  4LLT A;  2Z7H A;  3M00 A;  1DI1 A;  3B7L A;  3P8L A;  3EFQ A;  5H9D A;  3WCL A;  3KRC B;  3V1V A;  3TFN A;  4EA0 A;  3Q30 A;  4DWB A;  5JV2 F;  2F8Z F;  2E93 A;  5A0I A;  1WKZ A;  4F62 A;  3WCE A;  3NRI A;  2H8O A;  4QPF A;  5ER8 A; 
#chains in the Genus database with same CATH topology
 2ZCQ A;  4OMG A;  3M02 A;  3M9U A;  4N9U A;  5AEL A;  3KRO B;  3LG5 A;  4LA6 A;  4KVD A;  4NFJ F;  5B0J A;  4OKZ A;  5A0J A;  3ID0 A;  5EAU A;  1YJ4 A;  1KIZ A;  4LXW A;  3PDE A;  5IMN A;  5IK6 A;  2Z4Z A;  3V66 A;  1YHL A;  2E8X A;  3BNX A;  2Z4Y A;  2AZJ A;  3WEI A;  3OAB A;  3P5R A;  1YYU A;  2VF6 A;  3WJN A;  5ERO A;  4RXE A;  3AQB B;  3LEE A;  3G4F A;  4GP1 A;  3WEK A;  2OA6 A;  4RYP A;  3KBK A;  1YYS A;  2PS6 A;  3N5J F;  5DGS F;  3SAE A;  3ICN A;  4MC0 A;  2F94 F;  4LFV F;  3IPI A;  5DHK A;  2O1O A;  1PS1 A;  1N1Z A;  5AHU B;  5ILZ A;  3VJ8 A;  2ONG A;  3KRP A;  1EZF A;  2PS7 A;  2E92 A;  5HN9 A;  4E1E A;  4KQS A;  3PYB A;  1YQ7 A;  4LTV A;  3LGK A;  3WCC A;  4RNQ A;  3AE0 A;  1VG2 A;  4LPG F;  4LTZ A;  3CKE A;  3KRC A;  5HNA A;  5HN8 A;  4ZQ8 A;  2Z78 A;  5AFX A;  3RYE A;  1JFG A;  2E90 A;  5JA0 F;  5DGM F;  2E8V A;  4MC8 A;  3P41 A;  4GAX A;  3WCB A;  3WCG A;  3V1X A;  1UBY A;  3LGZ B;  3KRO A;  4JVJ F;  1ZW5 A;  5IVG A;  4LZ0 A;  3UCA A;  1HXA A;  3W7F A;  3NPK A;  5DIQ F;  4KFA A;  3Q2Z A;  4DXJ A;  3WSB A;  5HN7 A;  3S9V A;  3N49 F;  3TC1 A;  1N20 A;  2ZCS A;  5B0L A;  3AQC B;  3P5P A;  2E8T A;  3BNY A;  2Q58 A;  3ACY A;  2Z4X A;  5CG5 A;  4L2X F;  4RXD A;  3G4D A;  2F92 F;  4DZW A;  5ILI A;  1YHM A;  2P1C A;  3LK5 A;  5DHI A;  2F8C F;  3Q1O A;  3TS7 A;  3KRA B;  4DI5 A;  5B0I A;  2J5C A;  3WEJ A;  1YHK A;  2Z7I A;  2AZK A;  1N23 A;  3ZMB A;  5ILK A;  5ERN A;  2ONH A;  3S4J A;  2FTZ A;  1VG4 A;  4EA1 A;  4DEM F;  1DGP A;  3APZ A;  1FPS A;  5B0K A;  3WC9 A;  4OMH A;  3NF2 A;  3CP6 A;  3LZ9 A;  3VJD A;  2J1O A;  4E9Z A;  5KSX F;  2F9K F;  1WL0 A;  3N3L F;  3KRF B;  2Z4W A;  2Z4V A;  4LZC A;  3ACX A;  3N1W F;  4LZ3 A;  3SDR A;  2OPM A;  5EAS A;  2EWG A;  3QKC A;  3LJI A;  4JYX A;  2F7M F;  3ZMC A;  1N21 A;  3WJO A;  4K10 A;  4P0W A;  1HXC A;  4F6X A;  3WEG A;  4RXC A;  3WSA A;  1VG6 A;  1UBX A;  1YYT A;  4PVX F;  1UBV A;  5ILY A;  1HXG A;  2ZEV A;  5DJR F;  5IK9 A;  5C05 A;  2E8W A;  4Q23 A;  1RQJ A;  3KB9 A;  3DYF A;  5ERM A;  3ICK A;  4XQT F;  3SDV A;  2PS5 A;  1VG7 A;  3LMD A;  4KPD A;  2QIS A;  3KRA A;  3VJC A;  1HX9 A;  4JXY A;  3N0G A;  2ZEU A;  1WL1 A;  3LLW A;  1YYR A;  3N45 F;  3P8R A;  2AEL A;  4GP2 A;  4LUU A;  5E8H A;  2ZCR A;  3VJE A;  4FJQ A;  4LA5 A;  3ASX A;  2E91 A;  5EAT A;  3N3D A;  4N1Z F;  3ZOU A;  5CG6 A;  1YV5 A;  2E94 A;  5B01 A;  4KWD A;  4P0X A;  1YYQ A;  3RBM A;  5IN8 A;  3Q2Q A;  4LFG A;  2J1P A;  4H5E F;  3KRF A;  5IL8 A;  4KK2 A;  5E8L A;  3N6K F;  2Q80 A;  4JXN A;  3KRP B;  5I1U A;  1JFA A;  5DJP F;  2RAH A;  1V4I A;  4H5C F;  4HD1 A;  5B02 A;  2I19 A;  2AEK A;  2PS4 A;  1V4J A;  4NFI F;  3M01 A;  5IMI A;  5AYP A;  5B0M A;  3ADZ A;  3WCA A;  3DYH A;  5A0K A;  5DZ2 A;  3OYR A;  2ZCO A;  3LVS A;  4NG6 A;  4UMJ A;  4MC3 A;  2AZL A;  2AET A;  1V4E A;  2Z50 A;  3N1V F;  1KIY A;  3LSN A;  3VJB A;  5DJV F;  1V4H A;  3MZV A;  4OGU A;  3WCD A;  1V4K A;  3ICZ A;  5IK0 A;  3LOM A;  3OAC B;  3QQV A;  4KQU A;  5DW7 A;  1N24 A;  2PS8 A;  1HM4 A;  4LFE A;  1WL2 A;  5B00 A;  4QXS F;  3PH7 A;  3SDQ A;  3NPR A;  1HM7 A;  3SDU A;  3PYA A;  3WCF A;  4H5D F;  4XQS F;  3ZCD A;  4PVY F;  3TFV A;  1WY0 A;  1N22 A;  2FOR A;  2DH4 A;  3TFP A;  2Z52 A;  3RYW A;  3WCM A;  5IKA A;  4LIX A;  3ACW A;  4DWG A;  4DHD A;  3N5H F;  5IL3 A;  4NKE A;  3SDT A;  3MAV A;  3ZL6 A;  5ILD A;  2Q9Z A;  4KQ5 A;  4NFK F;  3WCI A;  3WCH A;  4KVW A;  4LOB A;  3IBA A;  3N0F A;  2OPN A;  4LLS A;  3WCJ A;  4LPH F;  1WMW A;  1RTR A;  1RQI A;  4GA3 A;  1VG3 A;  3EZ3 A;  4WK5 A;  4FP4 A;  1WL3 A;  3M0G A;  4P0V A;  4KVI A;  3OAB B;  4JZX A;  5DGN F;  3DYG A;  3ICM A;  1N1B A;  4XQR F;  3WEF A;  5JUZ F;  5JV1 F;  3CC9 A;  4NUA A;  4RXA A;  5IKH A;  3LDW A;  2E4O A;  2Q9Y A;  4F6V A;  2F89 F;  4EA2 A;  3OAC A;  4OKM A;  3VJ9 A;  3N46 F;  1UBW A;  5ILJ A;  3AQ0 A;  5E8K A;  4KKM A;  4KPJ A;  2ZY1 A;  4NKF A;  5B03 A;  5ILH A;  3RMG A;  2OGD A;  2E95 A;  5JV0 F;  3EGT A;  4JZB A;  5IMP A;  4KVY A;  3WE9 A;  3WEH A;  3VJA A;  3WJK A;  5IM1 A;  3PKO A;  4E9U A;  2E8U A;  4KUX A;  4LLT A;  2Z7H A;  3M00 A;  1DI1 A;  3B7L A;  3P8L A;  3EFQ A;  5H9D A;  3WCL A;  3KRC B;  3V1V A;  3TFN A;  4EA0 A;  3Q30 A;  4DWB A;  5JV2 F;  2F8Z F;  2E93 A;  5A0I A;  1WKZ A;  4F62 A;  3WCE A;  3NRI A;  2H8O A;  4QPF A;  5ER8 A; 
#chains in the Genus database with same CATH homology
 2ZCQ A;  4OMG A;  3M02 A;  3M9U A;  4N9U A;  5AEL A;  3KRO B;  3LG5 A;  4LA6 A;  4KVD A;  4NFJ F;  5B0J A;  4OKZ A;  5A0J A;  3ID0 A;  5EAU A;  1YJ4 A;  1KIZ A;  4LXW A;  3PDE A;  5IMN A;  5IK6 A;  2Z4Z A;  3V66 A;  1YHL A;  2E8X A;  3BNX A;  2Z4Y A;  2AZJ A;  3WEI A;  3OAB A;  3P5R A;  1YYU A;  2VF6 A;  3WJN A;  5ERO A;  4RXE A;  3AQB B;  3LEE A;  3G4F A;  4GP1 A;  3WEK A;  2OA6 A;  4RYP A;  3KBK A;  1YYS A;  2PS6 A;  3N5J F;  5DGS F;  3SAE A;  3ICN A;  4MC0 A;  2F94 F;  4LFV F;  3IPI A;  5DHK A;  2O1O A;  1PS1 A;  1N1Z A;  5AHU B;  5ILZ A;  3VJ8 A;  2ONG A;  3KRP A;  1EZF A;  2PS7 A;  2E92 A;  5HN9 A;  4E1E A;  4KQS A;  3PYB A;  1YQ7 A;  4LTV A;  3LGK A;  3WCC A;  4RNQ A;  3AE0 A;  1VG2 A;  4LPG F;  4LTZ A;  3CKE A;  3KRC A;  5HNA A;  5HN8 A;  4ZQ8 A;  2Z78 A;  5AFX A;  3RYE A;  1JFG A;  2E90 A;  5JA0 F;  5DGM F;  2E8V A;  4MC8 A;  3P41 A;  4GAX A;  3WCB A;  3WCG A;  3V1X A;  1UBY A;  3LGZ B;  3KRO A;  4JVJ F;  1ZW5 A;  5IVG A;  4LZ0 A;  3UCA A;  1HXA A;  3W7F A;  3NPK A;  5DIQ F;  4KFA A;  3Q2Z A;  4DXJ A;  3WSB A;  5HN7 A;  3S9V A;  3N49 F;  3TC1 A;  1N20 A;  2ZCS A;  5B0L A;  3AQC B;  3P5P A;  2E8T A;  3BNY A;  2Q58 A;  3ACY A;  2Z4X A;  5CG5 A;  4L2X F;  4RXD A;  3G4D A;  2F92 F;  4DZW A;  5ILI A;  1YHM A;  2P1C A;  3LK5 A;  5DHI A;  2F8C F;  3Q1O A;  3TS7 A;  3KRA B;  4DI5 A;  5B0I A;  2J5C A;  3WEJ A;  1YHK A;  2Z7I A;  2AZK A;  1N23 A;  3ZMB A;  5ILK A;  5ERN A;  2ONH A;  3S4J A;  2FTZ A;  1VG4 A;  4EA1 A;  4DEM F;  1DGP A;  3APZ A;  1FPS A;  5B0K A;  3WC9 A;  4OMH A;  3NF2 A;  3CP6 A;  3LZ9 A;  3VJD A;  2J1O A;  4E9Z A;  5KSX F;  2F9K F;  1WL0 A;  3N3L F;  3KRF B;  2Z4W A;  2Z4V A;  4LZC A;  3ACX A;  3N1W F;  4LZ3 A;  3SDR A;  2OPM A;  5EAS A;  2EWG A;  3QKC A;  3LJI A;  4JYX A;  2F7M F;  3ZMC A;  1N21 A;  3WJO A;  4K10 A;  4P0W A;  1HXC A;  4F6X A;  3WEG A;  4RXC A;  3WSA A;  1VG6 A;  1UBX A;  1YYT A;  4PVX F;  1UBV A;  5ILY A;  1HXG A;  2ZEV A;  5DJR F;  5IK9 A;  5C05 A;  2E8W A;  4Q23 A;  1RQJ A;  3KB9 A;  3DYF A;  5ERM A;  3ICK A;  4XQT F;  3SDV A;  2PS5 A;  1VG7 A;  3LMD A;  4KPD A;  2QIS A;  3KRA A;  3VJC A;  1HX9 A;  4JXY A;  3N0G A;  2ZEU A;  1WL1 A;  3LLW A;  1YYR A;  3N45 F;  3P8R A;  2AEL A;  4GP2 A;  4LUU A;  5E8H A;  2ZCR A;  3VJE A;  4FJQ A;  4LA5 A;  3ASX A;  2E91 A;  5EAT A;  3N3D A;  4N1Z F;  3ZOU A;  5CG6 A;  1YV5 A;  2E94 A;  5B01 A;  4KWD A;  4P0X A;  1YYQ A;  3RBM A;  5IN8 A;  3Q2Q A;  4LFG A;  2J1P A;  4H5E F;  3KRF A;  5IL8 A;  4KK2 A;  5E8L A;  3N6K F;  2Q80 A;  4JXN A;  3KRP B;  5I1U A;  1JFA A;  5DJP F;  2RAH A;  1V4I A;  4H5C F;  4HD1 A;  5B02 A;  2I19 A;  2AEK A;  2PS4 A;  1V4J A;  4NFI F;  3M01 A;  5IMI A;  5AYP A;  5B0M A;  3ADZ A;  3WCA A;  3DYH A;  5A0K A;  5DZ2 A;  3OYR A;  2ZCO A;  3LVS A;  4NG6 A;  4UMJ A;  4MC3 A;  2AZL A;  2AET A;  1V4E A;  2Z50 A;  3N1V F;  1KIY A;  3LSN A;  3VJB A;  5DJV F;  1V4H A;  3MZV A;  4OGU A;  3WCD A;  1V4K A;  3ICZ A;  5IK0 A;  3LOM A;  3OAC B;  3QQV A;  4KQU A;  5DW7 A;  1N24 A;  2PS8 A;  1HM4 A;  4LFE A;  1WL2 A;  5B00 A;  4QXS F;  3PH7 A;  3SDQ A;  3NPR A;  1HM7 A;  3SDU A;  3PYA A;  3WCF A;  4H5D F;  4XQS F;  3ZCD A;  4PVY F;  3TFV A;  1WY0 A;  1N22 A;  2FOR A;  2DH4 A;  3TFP A;  2Z52 A;  3RYW A;  3WCM A;  5IKA A;  4LIX A;  3ACW A;  4DWG A;  4DHD A;  3N5H F;  5IL3 A;  4NKE A;  3SDT A;  3MAV A;  3ZL6 A;  5ILD A;  2Q9Z A;  4KQ5 A;  4NFK F;  3WCI A;  3WCH A;  4KVW A;  4LOB A;  3IBA A;  3N0F A;  2OPN A;  4LLS A;  3WCJ A;  4LPH F;  1WMW A;  1RTR A;  1RQI A;  4GA3 A;  1VG3 A;  3EZ3 A;  4WK5 A;  4FP4 A;  1WL3 A;  3M0G A;  4P0V A;  4KVI A;  3OAB B;  4JZX A;  5DGN F;  3DYG A;  3ICM A;  1N1B A;  4XQR F;  3WEF A;  5JUZ F;  5JV1 F;  3CC9 A;  4NUA A;  4RXA A;  5IKH A;  3LDW A;  2E4O A;  2Q9Y A;  4F6V A;  2F89 F;  4EA2 A;  3OAC A;  4OKM A;  3VJ9 A;  3N46 F;  1UBW A;  5ILJ A;  3AQ0 A;  5E8K A;  4KKM A;  4KPJ A;  2ZY1 A;  4NKF A;  5B03 A;  5ILH A;  3RMG A;  2OGD A;  2E95 A;  5JV0 F;  3EGT A;  4JZB A;  5IMP A;  4KVY A;  3WE9 A;  3WEH A;  3VJA A;  3WJK A;  5IM1 A;  3PKO A;  4E9U A;  2E8U A;  4KUX A;  4LLT A;  2Z7H A;  3M00 A;  1DI1 A;  3B7L A;  3P8L A;  3EFQ A;  5H9D A;  3WCL A;  3KRC B;  3V1V A;  3TFN A;  4EA0 A;  3Q30 A;  4DWB A;  5JV2 F;  2F8Z F;  2E93 A;  5A0I A;  1WKZ A;  4F62 A;  3WCE A;  3NRI A;  2H8O A;  4QPF A;  5ER8 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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