4KVWA

Crystal structure of aspergillus terreus aristolochene synthase complexed with (3r,6r,9ar)-6,9a-dimethyl-3-(prop-1-en-2-yl)decahydroquinolizin-5-ium
Total Genus 132
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
132
sequence length
304
structure length
304
Chain Sequence
LEPPPSTFQPLCHPLVEEVSKEVDGYFLQHWNFPNEKARKKFVAAGFSRVTCLYFPKALDDRIHFACRLLTVLFLIDDLLEYMSFEEGSAYNEKLIPISRGDVLPDRSIPVEYIIYDLWESMRAHDREMADEILEPVFLFMRAQTDRTRARPMGLGGYLEYRERDVGKELLAALMRFSMGLKLSPSELQRVREIDANCSKHLSVVNDIYSYEKELYTSKTAHSEGGILCTSVQILAQEADVTAEAAKRVLFVMCREWELRHQLLVARLSAEGLETPGLAAYVEGLEYQMSGNELWSQTTLRYSV
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Mechanistic insights from the binding of substrate and carbocation intermediate analogues to aristolochene synthase.
pubmed doi rcsb
molecule tags Lyase/lyase inhibitor
source organism Aspergillus terreus
molecule keywords Aristolochene synthase
total genus 132
structure length 304
sequence length 304
chains with identical sequence B, C, D
ec nomenclature ec 4.2.3.9: Aristolochene synthase.
pdb deposition date 2013-05-23
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.600.10 Mainly Alpha Orthogonal Bundle Farnesyl Diphosphate Synthase Farnesyl Diphosphate Synthase 4kvwA00
4RXEA 5EASA 1EZFA 2PS7A 5B0IA 1UBVA 2Z50A 3PKOA 5IKAA 2VF6A 4NFJF 4P0XA 5AYPA 3WCHA 1KIYA 1N21A 4XQRF 1WL2A 4KVYA 5IL3A 1RQJA 3N1WF 3KBKA 3NRIA 2F92F 2OPMA 4KUXA 4PVYF 3ASXA 3CP6A 4MC0A 4EA1A 2Q9ZA 5B02A 4EA2A 2FTZA 4LZ0A 3KRCA 3ACYA 3EZ3A 1WKZA 5JV0F 3SDQA 5DJPF 3ZMBA 3LDWA 5A0KA 2RAHA 3V1XA 3KROB 2E94A 3N46F 4KQSA 4N9UA 4LLTA 1WMWA 3LSNA 4QPFA 5I1UA 3ZMCA 3N0FA 2FORA 2PS8A 2ZCRA 3LZ9A 3WEJA 3N5JF 5E8HA 5DGSF 1YYRA 2J5CA 3Q2ZA 4KFAA 5IKHA 3P8RA 4OKMA 5AHUB 3OABB 1HM4A 3OACA 2QISA 4K10A 4KQ5A 3G4FA 1UBXA 2ZEVA 3IPIA 4WK5A 1WY0A 1JFAA 3NF2A 2F8ZF 5E8LA 3WE9A 3N3LF 4LTVA 1YYSA 4KPDA 5ILDA 2Z78A 4DI5A 4JXNA 3RMGA 1WL3A 3ID0A 2E8VA 5IMPA 3TS7A 5DJVF 4GA3A 5DHKA 3TFVA 5HN8A 4MC3A 4DHDA 4NUAA 2DH4A 4NFKF 1HXAA 2ZY1A 4OKZA 3NPRA 4LFEA 3SDTA 4P0VA 3WCDA 3Q2QA 4KPJA 5B03A 5IK9A 3DYHA 1V4JA 3LK5A 5JV1F 3CC9A 1DGPA 3EGTA 3VJAA 4EA0A 4KWDA 3PYAA 3KRAA 4L2XF 2PS5A 3WJNA 3S9VA 5B0KA 2E95A 2Z4VA 4P0WA 5IMNA 1VG7A 2OA6A 5IK6A 1YJ4A 5KSXF 4RYPA 4DWBA 3ZL6A 4FJQA 3WJKA 4LA5A 3N0GA 3DYFA 1V4IA 2Q80A 3WCBA 3KRFB 5A0IA 2J1PA 3ICNA 5IMIA 2Q9YA 4JVJF 1YQ7A 3N6KF 3Q1OA 5CG5A 4LPGF 3B7LA 5DGMF 4LOBA 5EATA 5ILKA 3BNYA 3WSAA 4XQSF 5E8KA 5JUZF 3ACXA 4KVIA 5IM1A 4E9UA 2Z7HA 5B0JA 3WCLA 4ZQ8A 3W7FA 4RNQA 4H5CF 1YYTA 3KRPA 5IK0A 3VJ9A 4LPHF 1N23A 1YYUA 3N49F 4LLSA 3KB9A 1N24A 3AQCB 2AZJA 5IN8A 4KK2A 5HN9A 4LUUA 3OYRA 4OGUA 1V4EA 5B01A 3N45F 1WL0A 3M01A 2E91A 4HD1A 3LGZB 2Z4WA 4E9ZA 3KRFA 3PH7A 2PS6A 1DI1A 4DXJA 1N1ZA 2E8WA 3VJBA 2OPNA 3WCIA 1KIZA 4OMHA 3RBMA 3ADZA 4LTZA 2EWGA 2Z4XA 1YYQA 1N22A 5ILZA 3Q30A 3N1VF 4GP1A 3V66A 3LLWA 3ICKA 4NKFA 2E4OA 2OGDA 5DGNF 4RXAA 4DZWA 2J1OA 3KROA 4GP2A 3M02A 1V4HA 5DHIA 3AQBB 2H8OA 5EROA 4XQTF 2AETA 3KRCB 5DJRF 3APZA 4LFGA 5IL8A 2AELA 3LVSA 3N3DA 1ZW5A 4LXWA 2I19A 3SDVA 2E93A 1HX9A 5ILJA 3WEFA 4LIXA 5ER8A 5JA0F 3RYWA 3WEIA 2ZCSA 3LGKA 3AE0A 3OABA 1UBWA 3TC1A 5IVGA 3VJEA 3BNXA 4QXSF 2E92A 3UCAA 3WSBA 2E8TA 5ERMA 3PDEA 3P41A 3LEEA 1VG2A 2AZLA 2Z7IA 2ZCQA 4NFIF 3WCGA 5AFXA 3OACB 4NKEA 3MZVA 2ZCOA 3WCJA 2Z52A 3TFNA 3G4DA 1HXGA 1HXCA 1VG6A 5DIQF 3ICZA 5B0MA 4GAXA 4KVWA 3IBAA 4JZXA 4RXCA 3SAEA 3PYBA 3MAVA 1YV5A 4LZCA 3P5PA 5B0LA 1PS1A 3ZCDA 4E1EA 3P8LA 3NPKA 3WCCA 5HN7A 3WCFA 3M9UA 3SDUA 4H5EF 3WJOA 2Z4YA 5B00A 3WEGA 3LG5A 2ZEUA 4DEMF 3WCEA 4JZBA 3DYGA 4KQUA 2P1CA 2ONHA 4KKMA 1YHMA 1UBYA 1FPSA 3WC9A 3M00A 5ERNA 4F62A 2E90A 5HNAA 2PS4A 4PVXF 3KRAB 3WCAA 1VG3A 3WEKA 4LA6A 3ACWA 4LZ3A 4OMGA 4UMJA 5H9DA 2ONGA 1HM7A 2F89F 5JV2F 2E8UA 3SDRA 4H5DF 3M0GA 1V4KA 1YHKA 3WCMA 5A0JA 2F7MF 3CKEA 3VJDA 3N5HF 5ILYA 3P5RA 4F6XA 1VG4A 3V1VA 5ILHA 3QQVA 5EAUA 4KVDA 4LFVF 2F9KF 4NG6A 2O1OA 2Q58A 2AEKA 4JXYA 4JYXA 4MC8A 4Q23A 3RYEA 3S4JA 1YHLA 5DW7A 3WEHA 3LMDA 3LJIA 4DWGA 1RQIA 4FP4A 2Z4ZA 3ZOUA 5C05A 1N1BA 2F8CF 2E8XA 3ICMA 3KRPB 3VJ8A 3VJCA 1WL1A 2AZKA 5AELA 5DZ2A 3TFPA 3LOMA 5ILIA 4RXDA 1N20A 5CG6A 1JFGA 1RTRA 3QKCA 4N1ZF 3AQ0A 4F6VA 3EFQA 2F94F
chains in the Genus database with same CATH superfamily
4RXEA 5EASA 1EZFA 2PS7A 5B0IA 1UBVA 2Z50A 3PKOA 5IKAA 2VF6A 4NFJF 4P0XA 5AYPA 3WCHA 1KIYA 1N21A 4XQRF 1WL2A 4KVYA 5IL3A 1RQJA 3N1WF 3KBKA 3NRIA 2F92F 2OPMA 4KUXA 4PVYF 3ASXA 3CP6A 4MC0A 4EA1A 2Q9ZA 5B02A 4EA2A 2FTZA 4LZ0A 3KRCA 3ACYA 3EZ3A 1WKZA 5JV0F 3SDQA 5DJPF 3ZMBA 3LDWA 5A0KA 2RAHA 3V1XA 3KROB 2E94A 3N46F 4KQSA 4N9UA 4LLTA 1WMWA 3LSNA 4QPFA 5I1UA 3ZMCA 3N0FA 2FORA 2PS8A 2ZCRA 3LZ9A 3WEJA 3N5JF 5E8HA 5DGSF 1YYRA 2J5CA 3Q2ZA 4KFAA 5IKHA 3P8RA 4OKMA 5AHUB 3OABB 1HM4A 3OACA 2QISA 4K10A 4KQ5A 3G4FA 1UBXA 2ZEVA 3IPIA 4WK5A 1WY0A 1JFAA 3NF2A 2F8ZF 5E8LA 3WE9A 3N3LF 4LTVA 1YYSA 4KPDA 5ILDA 2Z78A 4DI5A 4JXNA 3RMGA 1WL3A 3ID0A 2E8VA 5IMPA 3TS7A 5DJVF 4GA3A 5DHKA 3TFVA 5HN8A 4MC3A 4DHDA 4NUAA 2DH4A 4NFKF 1HXAA 2ZY1A 4OKZA 3NPRA 4LFEA 3SDTA 4P0VA 3WCDA 3Q2QA 4KPJA 5B03A 5IK9A 3DYHA 1V4JA 3LK5A 5JV1F 3CC9A 1DGPA 3EGTA 3VJAA 4EA0A 4KWDA 3PYAA 3KRAA 4L2XF 2PS5A 3WJNA 3S9VA 5B0KA 2E95A 2Z4VA 4P0WA 5IMNA 1VG7A 2OA6A 5IK6A 1YJ4A 5KSXF 4RYPA 4DWBA 3ZL6A 4FJQA 3WJKA 4LA5A 3N0GA 3DYFA 1V4IA 2Q80A 3WCBA 3KRFB 5A0IA 2J1PA 3ICNA 5IMIA 2Q9YA 4JVJF 1YQ7A 3N6KF 3Q1OA 5CG5A 4LPGF 3B7LA 5DGMF 4LOBA 5EATA 5ILKA 3BNYA 3WSAA 4XQSF 5E8KA 5JUZF 3ACXA 4KVIA 5IM1A 4E9UA 2Z7HA 5B0JA 3WCLA 4ZQ8A 3W7FA 4RNQA 4H5CF 1YYTA 3KRPA 5IK0A 3VJ9A 4LPHF 1N23A 1YYUA 3N49F 4LLSA 3KB9A 1N24A 3AQCB 2AZJA 5IN8A 4KK2A 5HN9A 4LUUA 3OYRA 4OGUA 1V4EA 5B01A 3N45F 1WL0A 3M01A 2E91A 4HD1A 3LGZB 2Z4WA 4E9ZA 3KRFA 3PH7A 2PS6A 1DI1A 4DXJA 1N1ZA 2E8WA 3VJBA 2OPNA 3WCIA 1KIZA 4OMHA 3RBMA 3ADZA 4LTZA 2EWGA 2Z4XA 1YYQA 1N22A 5ILZA 3Q30A 3N1VF 4GP1A 3V66A 3LLWA 3ICKA 4NKFA 2E4OA 2OGDA 5DGNF 4RXAA 4DZWA 2J1OA 3KROA 4GP2A 3M02A 1V4HA 5DHIA 3AQBB 2H8OA 5EROA 4XQTF 2AETA 3KRCB 5DJRF 3APZA 4LFGA 5IL8A 2AELA 3LVSA 3N3DA 1ZW5A 4LXWA 2I19A 3SDVA 2E93A 1HX9A 5ILJA 3WEFA 4LIXA 5ER8A 5JA0F 3RYWA 3WEIA 2ZCSA 3LGKA 3AE0A 3OABA 1UBWA 3TC1A 5IVGA 3VJEA 3BNXA 4QXSF 2E92A 3UCAA 3WSBA 2E8TA 5ERMA 3PDEA 3P41A 3LEEA 1VG2A 2AZLA 2Z7IA 2ZCQA 4NFIF 3WCGA 5AFXA 3OACB 4NKEA 3MZVA 2ZCOA 3WCJA 2Z52A 3TFNA 3G4DA 1HXGA 1HXCA 1VG6A 5DIQF 3ICZA 5B0MA 4GAXA 4KVWA 3IBAA 4JZXA 4RXCA 3SAEA 3PYBA 3MAVA 1YV5A 4LZCA 3P5PA 5B0LA 1PS1A 3ZCDA 4E1EA 3P8LA 3NPKA 3WCCA 5HN7A 3WCFA 3M9UA 3SDUA 4H5EF 3WJOA 2Z4YA 5B00A 3WEGA 3LG5A 2ZEUA 4DEMF 3WCEA 4JZBA 3DYGA 4KQUA 2P1CA 2ONHA 4KKMA 1YHMA 1UBYA 1FPSA 3WC9A 3M00A 5ERNA 4F62A 2E90A 5HNAA 2PS4A 4PVXF 3KRAB 3WCAA 1VG3A 3WEKA 4LA6A 3ACWA 4LZ3A 4OMGA 4UMJA 5H9DA 2ONGA 1HM7A 2F89F 5JV2F 2E8UA 3SDRA 4H5DF 3M0GA 1V4KA 1YHKA 3WCMA 5A0JA 2F7MF 3CKEA 3VJDA 3N5HF 5ILYA 3P5RA 4F6XA 1VG4A 3V1VA 5ILHA 3QQVA 5EAUA 4KVDA 4LFVF 2F9KF 4NG6A 2O1OA 2Q58A 2AEKA 4JXYA 4JYXA 4MC8A 4Q23A 3RYEA 3S4JA 1YHLA 5DW7A 3WEHA 3LMDA 3LJIA 4DWGA 1RQIA 4FP4A 2Z4ZA 3ZOUA 5C05A 1N1BA 2F8CF 2E8XA 3ICMA 3KRPB 3VJ8A 3VJCA 1WL1A 2AZKA 5AELA 5DZ2A 3TFPA 3LOMA 5ILIA 4RXDA 1N20A 5CG6A 1JFGA 1RTRA 3QKCA 4N1ZF 3AQ0A 4F6VA 3EFQA 2F94F
chains in the Genus database with same CATH topology
4RXEA 5EASA 1EZFA 2PS7A 5B0IA 1UBVA 2Z50A 3PKOA 5IKAA 2VF6A 4NFJF 4P0XA 5AYPA 3WCHA 1KIYA 1N21A 4XQRF 1WL2A 4KVYA 5IL3A 1RQJA 3N1WF 3KBKA 3NRIA 2F92F 2OPMA 4KUXA 4PVYF 3ASXA 3CP6A 4MC0A 4EA1A 2Q9ZA 5B02A 4EA2A 2FTZA 4LZ0A 3KRCA 3ACYA 3EZ3A 1WKZA 5JV0F 3SDQA 5DJPF 3ZMBA 3LDWA 5A0KA 2RAHA 3V1XA 3KROB 2E94A 3N46F 4KQSA 4N9UA 4LLTA 1WMWA 3LSNA 4QPFA 5I1UA 3ZMCA 3N0FA 2FORA 2PS8A 2ZCRA 3LZ9A 3WEJA 3N5JF 5E8HA 5DGSF 1YYRA 2J5CA 3Q2ZA 4KFAA 5IKHA 3P8RA 4OKMA 5AHUB 3OABB 1HM4A 3OACA 2QISA 4K10A 4KQ5A 3G4FA 1UBXA 2ZEVA 3IPIA 4WK5A 1WY0A 1JFAA 3NF2A 2F8ZF 5E8LA 3WE9A 3N3LF 4LTVA 1YYSA 4KPDA 5ILDA 2Z78A 4DI5A 4JXNA 3RMGA 1WL3A 3ID0A 2E8VA 5IMPA 3TS7A 5DJVF 4GA3A 5DHKA 3TFVA 5HN8A 4MC3A 4DHDA 4NUAA 2DH4A 4NFKF 1HXAA 2ZY1A 4OKZA 3NPRA 4LFEA 3SDTA 4P0VA 3WCDA 3Q2QA 4KPJA 5B03A 5IK9A 3DYHA 1V4JA 3LK5A 5JV1F 3CC9A 1DGPA 3EGTA 3VJAA 4EA0A 4KWDA 3PYAA 3KRAA 4L2XF 2PS5A 3WJNA 3S9VA 5B0KA 2E95A 2Z4VA 4P0WA 5IMNA 1VG7A 2OA6A 5IK6A 1YJ4A 5KSXF 4RYPA 4DWBA 3ZL6A 4FJQA 3WJKA 4LA5A 3N0GA 3DYFA 1V4IA 2Q80A 3WCBA 3KRFB 5A0IA 2J1PA 3ICNA 5IMIA 2Q9YA 4JVJF 1YQ7A 3N6KF 3Q1OA 5CG5A 4LPGF 3B7LA 5DGMF 4LOBA 5EATA 5ILKA 3BNYA 3WSAA 4XQSF 5E8KA 5JUZF 3ACXA 4KVIA 5IM1A 4E9UA 2Z7HA 5B0JA 3WCLA 4ZQ8A 3W7FA 4RNQA 4H5CF 1YYTA 3KRPA 5IK0A 3VJ9A 4LPHF 1N23A 1YYUA 3N49F 4LLSA 3KB9A 1N24A 3AQCB 2AZJA 5IN8A 4KK2A 5HN9A 4LUUA 3OYRA 4OGUA 1V4EA 5B01A 3N45F 1WL0A 3M01A 2E91A 4HD1A 3LGZB 2Z4WA 4E9ZA 3KRFA 3PH7A 2PS6A 1DI1A 4DXJA 1N1ZA 2E8WA 3VJBA 2OPNA 3WCIA 1KIZA 4OMHA 3RBMA 3ADZA 4LTZA 2EWGA 2Z4XA 1YYQA 1N22A 5ILZA 3Q30A 3N1VF 4GP1A 3V66A 3LLWA 3ICKA 4NKFA 2E4OA 2OGDA 5DGNF 4RXAA 4DZWA 2J1OA 3KROA 4GP2A 3M02A 1V4HA 5DHIA 3AQBB 2H8OA 5EROA 4XQTF 2AETA 3KRCB 5DJRF 3APZA 4LFGA 5IL8A 2AELA 3LVSA 3N3DA 1ZW5A 4LXWA 2I19A 3SDVA 2E93A 1HX9A 5ILJA 3WEFA 4LIXA 5ER8A 5JA0F 3RYWA 3WEIA 2ZCSA 3LGKA 3AE0A 3OABA 1UBWA 3TC1A 5IVGA 3VJEA 3BNXA 4QXSF 2E92A 3UCAA 3WSBA 2E8TA 5ERMA 3PDEA 3P41A 3LEEA 1VG2A 2AZLA 2Z7IA 2ZCQA 4NFIF 3WCGA 5AFXA 3OACB 4NKEA 3MZVA 2ZCOA 3WCJA 2Z52A 3TFNA 3G4DA 1HXGA 1HXCA 1VG6A 5DIQF 3ICZA 5B0MA 4GAXA 4KVWA 3IBAA 4JZXA 4RXCA 3SAEA 3PYBA 3MAVA 1YV5A 4LZCA 3P5PA 5B0LA 1PS1A 3ZCDA 4E1EA 3P8LA 3NPKA 3WCCA 5HN7A 3WCFA 3M9UA 3SDUA 4H5EF 3WJOA 2Z4YA 5B00A 3WEGA 3LG5A 2ZEUA 4DEMF 3WCEA 4JZBA 3DYGA 4KQUA 2P1CA 2ONHA 4KKMA 1YHMA 1UBYA 1FPSA 3WC9A 3M00A 5ERNA 4F62A 2E90A 5HNAA 2PS4A 4PVXF 3KRAB 3WCAA 1VG3A 3WEKA 4LA6A 3ACWA 4LZ3A 4OMGA 4UMJA 5H9DA 2ONGA 1HM7A 2F89F 5JV2F 2E8UA 3SDRA 4H5DF 3M0GA 1V4KA 1YHKA 3WCMA 5A0JA 2F7MF 3CKEA 3VJDA 3N5HF 5ILYA 3P5RA 4F6XA 1VG4A 3V1VA 5ILHA 3QQVA 5EAUA 4KVDA 4LFVF 2F9KF 4NG6A 2O1OA 2Q58A 2AEKA 4JXYA 4JYXA 4MC8A 4Q23A 3RYEA 3S4JA 1YHLA 5DW7A 3WEHA 3LMDA 3LJIA 4DWGA 1RQIA 4FP4A 2Z4ZA 3ZOUA 5C05A 1N1BA 2F8CF 2E8XA 3ICMA 3KRPB 3VJ8A 3VJCA 1WL1A 2AZKA 5AELA 5DZ2A 3TFPA 3LOMA 5ILIA 4RXDA 1N20A 5CG6A 1JFGA 1RTRA 3QKCA 4N1ZF 3AQ0A 4F6VA 3EFQA 2F94F
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4RXE A;  5EAS A;  1EZF A;  2PS7 A;  5B0I A;  1UBV A;  2Z50 A;  3PKO A;  5IKA A;  2VF6 A;  4NFJ F;  4P0X A;  5AYP A;  3WCH A;  1KIY A;  1N21 A;  4XQR F;  1WL2 A;  4KVY A;  5IL3 A;  1RQJ A;  3N1W F;  3KBK A;  3NRI A;  2F92 F;  2OPM A;  4KUX A;  4PVY F;  3ASX A;  3CP6 A;  4MC0 A;  4EA1 A;  2Q9Z A;  5B02 A;  4EA2 A;  2FTZ A;  4LZ0 A;  3KRC A;  3ACY A;  3EZ3 A;  1WKZ A;  5JV0 F;  3SDQ A;  5DJP F;  3ZMB A;  3LDW A;  5A0K A;  2RAH A;  3V1X A;  3KRO B;  2E94 A;  3N46 F;  4KQS A;  4N9U A;  4LLT A;  1WMW A;  3LSN A;  4QPF A;  5I1U A;  3ZMC A;  3N0F A;  2FOR A;  2PS8 A;  2ZCR A;  3LZ9 A;  3WEJ A;  3N5J F;  5E8H A;  5DGS F;  1YYR A;  2J5C A;  3Q2Z A;  4KFA A;  5IKH A;  3P8R A;  4OKM A;  5AHU B;  3OAB B;  1HM4 A;  3OAC A;  2QIS A;  4K10 A;  4KQ5 A;  3G4F A;  1UBX A;  2ZEV A;  3IPI A;  4WK5 A;  1WY0 A;  1JFA A;  3NF2 A;  2F8Z F;  5E8L A;  3WE9 A;  3N3L F;  4LTV A;  1YYS A;  4KPD A;  5ILD A;  2Z78 A;  4DI5 A;  4JXN A;  3RMG A;  1WL3 A;  3ID0 A;  2E8V A;  5IMP A;  3TS7 A;  5DJV F;  4GA3 A;  5DHK A;  3TFV A;  5HN8 A;  4MC3 A;  4DHD A;  4NUA A;  2DH4 A;  4NFK F;  1HXA A;  2ZY1 A;  4OKZ A;  3NPR A;  4LFE A;  3SDT A;  4P0V A;  3WCD A;  3Q2Q A;  4KPJ A;  5B03 A;  5IK9 A;  3DYH A;  1V4J A;  3LK5 A;  5JV1 F;  3CC9 A;  1DGP A;  3EGT A;  3VJA A;  4EA0 A;  4KWD A;  3PYA A;  3KRA A;  4L2X F;  2PS5 A;  3WJN A;  3S9V A;  5B0K A;  2E95 A;  2Z4V A;  4P0W A;  5IMN A;  1VG7 A;  2OA6 A;  5IK6 A;  1YJ4 A;  5KSX F;  4RYP A;  4DWB A;  3ZL6 A;  4FJQ A;  3WJK A;  4LA5 A;  3N0G A;  3DYF A;  1V4I A;  2Q80 A;  3WCB A;  3KRF B;  5A0I A;  2J1P A;  3ICN A;  5IMI A;  2Q9Y A;  4JVJ F;  1YQ7 A;  3N6K F;  3Q1O A;  5CG5 A;  4LPG F;  3B7L A;  5DGM F;  4LOB A;  5EAT A;  5ILK A;  3BNY A;  3WSA A;  4XQS F;  5E8K A;  5JUZ F;  3ACX A;  4KVI A;  5IM1 A;  4E9U A;  2Z7H A;  5B0J A;  3WCL A;  4ZQ8 A;  3W7F A;  4RNQ A;  4H5C F;  1YYT A;  3KRP A;  5IK0 A;  3VJ9 A;  4LPH F;  1N23 A;  1YYU A;  3N49 F;  4LLS A;  3KB9 A;  1N24 A;  3AQC B;  2AZJ A;  5IN8 A;  4KK2 A;  5HN9 A;  4LUU A;  3OYR A;  4OGU A;  1V4E A;  5B01 A;  3N45 F;  1WL0 A;  3M01 A;  2E91 A;  4HD1 A;  3LGZ B;  2Z4W A;  4E9Z A;  3KRF A;  3PH7 A;  2PS6 A;  1DI1 A;  4DXJ A;  1N1Z A;  2E8W A;  3VJB A;  2OPN A;  3WCI A;  1KIZ A;  4OMH A;  3RBM A;  3ADZ A;  4LTZ A;  2EWG A;  2Z4X A;  1YYQ A;  1N22 A;  5ILZ A;  3Q30 A;  3N1V F;  4GP1 A;  3V66 A;  3LLW A;  3ICK A;  4NKF A;  2E4O A;  2OGD A;  5DGN F;  4RXA A;  4DZW A;  2J1O A;  3KRO A;  4GP2 A;  3M02 A;  1V4H A;  5DHI A;  3AQB B;  2H8O A;  5ERO A;  4XQT F;  2AET A;  3KRC B;  5DJR F;  3APZ A;  4LFG A;  5IL8 A;  2AEL A;  3LVS A;  3N3D A;  1ZW5 A;  4LXW A;  2I19 A;  3SDV A;  2E93 A;  1HX9 A;  5ILJ A;  3WEF A;  4LIX A;  5ER8 A;  5JA0 F;  3RYW A;  3WEI A;  2ZCS A;  3LGK A;  3AE0 A;  3OAB A;  1UBW A;  3TC1 A;  5IVG A;  3VJE A;  3BNX A;  4QXS F;  2E92 A;  3UCA A;  3WSB A;  2E8T A;  5ERM A;  3PDE A;  3P41 A;  3LEE A;  1VG2 A;  2AZL A;  2Z7I A;  2ZCQ A;  4NFI F;  3WCG A;  5AFX A;  3OAC B;  4NKE A;  3MZV A;  2ZCO A;  3WCJ A;  2Z52 A;  3TFN A;  3G4D A;  1HXG A;  1HXC A;  1VG6 A;  5DIQ F;  3ICZ A;  5B0M A;  4GAX A;  4KVW A;  3IBA A;  4JZX A;  4RXC A;  3SAE A;  3PYB A;  3MAV A;  1YV5 A;  4LZC A;  3P5P A;  5B0L A;  1PS1 A;  3ZCD A;  4E1E A;  3P8L A;  3NPK A;  3WCC A;  5HN7 A;  3WCF A;  3M9U A;  3SDU A;  4H5E F;  3WJO A;  2Z4Y A;  5B00 A;  3WEG A;  3LG5 A;  2ZEU A;  4DEM F;  3WCE A;  4JZB A;  3DYG A;  4KQU A;  2P1C A;  2ONH A;  4KKM A;  1YHM A;  1UBY A;  1FPS A;  3WC9 A;  3M00 A;  5ERN A;  4F62 A;  2E90 A;  5HNA A;  2PS4 A;  4PVX F;  3KRA B;  3WCA A;  1VG3 A;  3WEK A;  4LA6 A;  3ACW A;  4LZ3 A;  4OMG A;  4UMJ A;  5H9D A;  2ONG A;  1HM7 A;  2F89 F;  5JV2 F;  2E8U A;  3SDR A;  4H5D F;  3M0G A;  1V4K A;  1YHK A;  3WCM A;  5A0J A;  2F7M F;  3CKE A;  3VJD A;  3N5H F;  5ILY A;  3P5R A;  4F6X A;  1VG4 A;  3V1V A;  5ILH A;  3QQV A;  5EAU A;  4KVD A;  4LFV F;  2F9K F;  4NG6 A;  2O1O A;  2Q58 A;  2AEK A;  4JXY A;  4JYX A;  4MC8 A;  4Q23 A;  3RYE A;  3S4J A;  1YHL A;  5DW7 A;  3WEH A;  3LMD A;  3LJI A;  4DWG A;  1RQI A;  4FP4 A;  2Z4Z A;  3ZOU A;  5C05 A;  1N1B A;  2F8C F;  2E8X A;  3ICM A;  3KRP B;  3VJ8 A;  3VJC A;  1WL1 A;  2AZK A;  5AEL A;  5DZ2 A;  3TFP A;  3LOM A;  5ILI A;  4RXD A;  1N20 A;  5CG6 A;  1JFG A;  1RTR A;  3QKC A;  4N1Z F;  3AQ0 A;  4F6V A;  3EFQ A;  2F94 F; 
#chains in the Genus database with same CATH topology
 4RXE A;  5EAS A;  1EZF A;  2PS7 A;  5B0I A;  1UBV A;  2Z50 A;  3PKO A;  5IKA A;  2VF6 A;  4NFJ F;  4P0X A;  5AYP A;  3WCH A;  1KIY A;  1N21 A;  4XQR F;  1WL2 A;  4KVY A;  5IL3 A;  1RQJ A;  3N1W F;  3KBK A;  3NRI A;  2F92 F;  2OPM A;  4KUX A;  4PVY F;  3ASX A;  3CP6 A;  4MC0 A;  4EA1 A;  2Q9Z A;  5B02 A;  4EA2 A;  2FTZ A;  4LZ0 A;  3KRC A;  3ACY A;  3EZ3 A;  1WKZ A;  5JV0 F;  3SDQ A;  5DJP F;  3ZMB A;  3LDW A;  5A0K A;  2RAH A;  3V1X A;  3KRO B;  2E94 A;  3N46 F;  4KQS A;  4N9U A;  4LLT A;  1WMW A;  3LSN A;  4QPF A;  5I1U A;  3ZMC A;  3N0F A;  2FOR A;  2PS8 A;  2ZCR A;  3LZ9 A;  3WEJ A;  3N5J F;  5E8H A;  5DGS F;  1YYR A;  2J5C A;  3Q2Z A;  4KFA A;  5IKH A;  3P8R A;  4OKM A;  5AHU B;  3OAB B;  1HM4 A;  3OAC A;  2QIS A;  4K10 A;  4KQ5 A;  3G4F A;  1UBX A;  2ZEV A;  3IPI A;  4WK5 A;  1WY0 A;  1JFA A;  3NF2 A;  2F8Z F;  5E8L A;  3WE9 A;  3N3L F;  4LTV A;  1YYS A;  4KPD A;  5ILD A;  2Z78 A;  4DI5 A;  4JXN A;  3RMG A;  1WL3 A;  3ID0 A;  2E8V A;  5IMP A;  3TS7 A;  5DJV F;  4GA3 A;  5DHK A;  3TFV A;  5HN8 A;  4MC3 A;  4DHD A;  4NUA A;  2DH4 A;  4NFK F;  1HXA A;  2ZY1 A;  4OKZ A;  3NPR A;  4LFE A;  3SDT A;  4P0V A;  3WCD A;  3Q2Q A;  4KPJ A;  5B03 A;  5IK9 A;  3DYH A;  1V4J A;  3LK5 A;  5JV1 F;  3CC9 A;  1DGP A;  3EGT A;  3VJA A;  4EA0 A;  4KWD A;  3PYA A;  3KRA A;  4L2X F;  2PS5 A;  3WJN A;  3S9V A;  5B0K A;  2E95 A;  2Z4V A;  4P0W A;  5IMN A;  1VG7 A;  2OA6 A;  5IK6 A;  1YJ4 A;  5KSX F;  4RYP A;  4DWB A;  3ZL6 A;  4FJQ A;  3WJK A;  4LA5 A;  3N0G A;  3DYF A;  1V4I A;  2Q80 A;  3WCB A;  3KRF B;  5A0I A;  2J1P A;  3ICN A;  5IMI A;  2Q9Y A;  4JVJ F;  1YQ7 A;  3N6K F;  3Q1O A;  5CG5 A;  4LPG F;  3B7L A;  5DGM F;  4LOB A;  5EAT A;  5ILK A;  3BNY A;  3WSA A;  4XQS F;  5E8K A;  5JUZ F;  3ACX A;  4KVI A;  5IM1 A;  4E9U A;  2Z7H A;  5B0J A;  3WCL A;  4ZQ8 A;  3W7F A;  4RNQ A;  4H5C F;  1YYT A;  3KRP A;  5IK0 A;  3VJ9 A;  4LPH F;  1N23 A;  1YYU A;  3N49 F;  4LLS A;  3KB9 A;  1N24 A;  3AQC B;  2AZJ A;  5IN8 A;  4KK2 A;  5HN9 A;  4LUU A;  3OYR A;  4OGU A;  1V4E A;  5B01 A;  3N45 F;  1WL0 A;  3M01 A;  2E91 A;  4HD1 A;  3LGZ B;  2Z4W A;  4E9Z A;  3KRF A;  3PH7 A;  2PS6 A;  1DI1 A;  4DXJ A;  1N1Z A;  2E8W A;  3VJB A;  2OPN A;  3WCI A;  1KIZ A;  4OMH A;  3RBM A;  3ADZ A;  4LTZ A;  2EWG A;  2Z4X A;  1YYQ A;  1N22 A;  5ILZ A;  3Q30 A;  3N1V F;  4GP1 A;  3V66 A;  3LLW A;  3ICK A;  4NKF A;  2E4O A;  2OGD A;  5DGN F;  4RXA A;  4DZW A;  2J1O A;  3KRO A;  4GP2 A;  3M02 A;  1V4H A;  5DHI A;  3AQB B;  2H8O A;  5ERO A;  4XQT F;  2AET A;  3KRC B;  5DJR F;  3APZ A;  4LFG A;  5IL8 A;  2AEL A;  3LVS A;  3N3D A;  1ZW5 A;  4LXW A;  2I19 A;  3SDV A;  2E93 A;  1HX9 A;  5ILJ A;  3WEF A;  4LIX A;  5ER8 A;  5JA0 F;  3RYW A;  3WEI A;  2ZCS A;  3LGK A;  3AE0 A;  3OAB A;  1UBW A;  3TC1 A;  5IVG A;  3VJE A;  3BNX A;  4QXS F;  2E92 A;  3UCA A;  3WSB A;  2E8T A;  5ERM A;  3PDE A;  3P41 A;  3LEE A;  1VG2 A;  2AZL A;  2Z7I A;  2ZCQ A;  4NFI F;  3WCG A;  5AFX A;  3OAC B;  4NKE A;  3MZV A;  2ZCO A;  3WCJ A;  2Z52 A;  3TFN A;  3G4D A;  1HXG A;  1HXC A;  1VG6 A;  5DIQ F;  3ICZ A;  5B0M A;  4GAX A;  4KVW A;  3IBA A;  4JZX A;  4RXC A;  3SAE A;  3PYB A;  3MAV A;  1YV5 A;  4LZC A;  3P5P A;  5B0L A;  1PS1 A;  3ZCD A;  4E1E A;  3P8L A;  3NPK A;  3WCC A;  5HN7 A;  3WCF A;  3M9U A;  3SDU A;  4H5E F;  3WJO A;  2Z4Y A;  5B00 A;  3WEG A;  3LG5 A;  2ZEU A;  4DEM F;  3WCE A;  4JZB A;  3DYG A;  4KQU A;  2P1C A;  2ONH A;  4KKM A;  1YHM A;  1UBY A;  1FPS A;  3WC9 A;  3M00 A;  5ERN A;  4F62 A;  2E90 A;  5HNA A;  2PS4 A;  4PVX F;  3KRA B;  3WCA A;  1VG3 A;  3WEK A;  4LA6 A;  3ACW A;  4LZ3 A;  4OMG A;  4UMJ A;  5H9D A;  2ONG A;  1HM7 A;  2F89 F;  5JV2 F;  2E8U A;  3SDR A;  4H5D F;  3M0G A;  1V4K A;  1YHK A;  3WCM A;  5A0J A;  2F7M F;  3CKE A;  3VJD A;  3N5H F;  5ILY A;  3P5R A;  4F6X A;  1VG4 A;  3V1V A;  5ILH A;  3QQV A;  5EAU A;  4KVD A;  4LFV F;  2F9K F;  4NG6 A;  2O1O A;  2Q58 A;  2AEK A;  4JXY A;  4JYX A;  4MC8 A;  4Q23 A;  3RYE A;  3S4J A;  1YHL A;  5DW7 A;  3WEH A;  3LMD A;  3LJI A;  4DWG A;  1RQI A;  4FP4 A;  2Z4Z A;  3ZOU A;  5C05 A;  1N1B A;  2F8C F;  2E8X A;  3ICM A;  3KRP B;  3VJ8 A;  3VJC A;  1WL1 A;  2AZK A;  5AEL A;  5DZ2 A;  3TFP A;  3LOM A;  5ILI A;  4RXD A;  1N20 A;  5CG6 A;  1JFG A;  1RTR A;  3QKC A;  4N1Z F;  3AQ0 A;  4F6V A;  3EFQ A;  2F94 F; 
#chains in the Genus database with same CATH homology
 4RXE A;  5EAS A;  1EZF A;  2PS7 A;  5B0I A;  1UBV A;  2Z50 A;  3PKO A;  5IKA A;  2VF6 A;  4NFJ F;  4P0X A;  5AYP A;  3WCH A;  1KIY A;  1N21 A;  4XQR F;  1WL2 A;  4KVY A;  5IL3 A;  1RQJ A;  3N1W F;  3KBK A;  3NRI A;  2F92 F;  2OPM A;  4KUX A;  4PVY F;  3ASX A;  3CP6 A;  4MC0 A;  4EA1 A;  2Q9Z A;  5B02 A;  4EA2 A;  2FTZ A;  4LZ0 A;  3KRC A;  3ACY A;  3EZ3 A;  1WKZ A;  5JV0 F;  3SDQ A;  5DJP F;  3ZMB A;  3LDW A;  5A0K A;  2RAH A;  3V1X A;  3KRO B;  2E94 A;  3N46 F;  4KQS A;  4N9U A;  4LLT A;  1WMW A;  3LSN A;  4QPF A;  5I1U A;  3ZMC A;  3N0F A;  2FOR A;  2PS8 A;  2ZCR A;  3LZ9 A;  3WEJ A;  3N5J F;  5E8H A;  5DGS F;  1YYR A;  2J5C A;  3Q2Z A;  4KFA A;  5IKH A;  3P8R A;  4OKM A;  5AHU B;  3OAB B;  1HM4 A;  3OAC A;  2QIS A;  4K10 A;  4KQ5 A;  3G4F A;  1UBX A;  2ZEV A;  3IPI A;  4WK5 A;  1WY0 A;  1JFA A;  3NF2 A;  2F8Z F;  5E8L A;  3WE9 A;  3N3L F;  4LTV A;  1YYS A;  4KPD A;  5ILD A;  2Z78 A;  4DI5 A;  4JXN A;  3RMG A;  1WL3 A;  3ID0 A;  2E8V A;  5IMP A;  3TS7 A;  5DJV F;  4GA3 A;  5DHK A;  3TFV A;  5HN8 A;  4MC3 A;  4DHD A;  4NUA A;  2DH4 A;  4NFK F;  1HXA A;  2ZY1 A;  4OKZ A;  3NPR A;  4LFE A;  3SDT A;  4P0V A;  3WCD A;  3Q2Q A;  4KPJ A;  5B03 A;  5IK9 A;  3DYH A;  1V4J A;  3LK5 A;  5JV1 F;  3CC9 A;  1DGP A;  3EGT A;  3VJA A;  4EA0 A;  4KWD A;  3PYA A;  3KRA A;  4L2X F;  2PS5 A;  3WJN A;  3S9V A;  5B0K A;  2E95 A;  2Z4V A;  4P0W A;  5IMN A;  1VG7 A;  2OA6 A;  5IK6 A;  1YJ4 A;  5KSX F;  4RYP A;  4DWB A;  3ZL6 A;  4FJQ A;  3WJK A;  4LA5 A;  3N0G A;  3DYF A;  1V4I A;  2Q80 A;  3WCB A;  3KRF B;  5A0I A;  2J1P A;  3ICN A;  5IMI A;  2Q9Y A;  4JVJ F;  1YQ7 A;  3N6K F;  3Q1O A;  5CG5 A;  4LPG F;  3B7L A;  5DGM F;  4LOB A;  5EAT A;  5ILK A;  3BNY A;  3WSA A;  4XQS F;  5E8K A;  5JUZ F;  3ACX A;  4KVI A;  5IM1 A;  4E9U A;  2Z7H A;  5B0J A;  3WCL A;  4ZQ8 A;  3W7F A;  4RNQ A;  4H5C F;  1YYT A;  3KRP A;  5IK0 A;  3VJ9 A;  4LPH F;  1N23 A;  1YYU A;  3N49 F;  4LLS A;  3KB9 A;  1N24 A;  3AQC B;  2AZJ A;  5IN8 A;  4KK2 A;  5HN9 A;  4LUU A;  3OYR A;  4OGU A;  1V4E A;  5B01 A;  3N45 F;  1WL0 A;  3M01 A;  2E91 A;  4HD1 A;  3LGZ B;  2Z4W A;  4E9Z A;  3KRF A;  3PH7 A;  2PS6 A;  1DI1 A;  4DXJ A;  1N1Z A;  2E8W A;  3VJB A;  2OPN A;  3WCI A;  1KIZ A;  4OMH A;  3RBM A;  3ADZ A;  4LTZ A;  2EWG A;  2Z4X A;  1YYQ A;  1N22 A;  5ILZ A;  3Q30 A;  3N1V F;  4GP1 A;  3V66 A;  3LLW A;  3ICK A;  4NKF A;  2E4O A;  2OGD A;  5DGN F;  4RXA A;  4DZW A;  2J1O A;  3KRO A;  4GP2 A;  3M02 A;  1V4H A;  5DHI A;  3AQB B;  2H8O A;  5ERO A;  4XQT F;  2AET A;  3KRC B;  5DJR F;  3APZ A;  4LFG A;  5IL8 A;  2AEL A;  3LVS A;  3N3D A;  1ZW5 A;  4LXW A;  2I19 A;  3SDV A;  2E93 A;  1HX9 A;  5ILJ A;  3WEF A;  4LIX A;  5ER8 A;  5JA0 F;  3RYW A;  3WEI A;  2ZCS A;  3LGK A;  3AE0 A;  3OAB A;  1UBW A;  3TC1 A;  5IVG A;  3VJE A;  3BNX A;  4QXS F;  2E92 A;  3UCA A;  3WSB A;  2E8T A;  5ERM A;  3PDE A;  3P41 A;  3LEE A;  1VG2 A;  2AZL A;  2Z7I A;  2ZCQ A;  4NFI F;  3WCG A;  5AFX A;  3OAC B;  4NKE A;  3MZV A;  2ZCO A;  3WCJ A;  2Z52 A;  3TFN A;  3G4D A;  1HXG A;  1HXC A;  1VG6 A;  5DIQ F;  3ICZ A;  5B0M A;  4GAX A;  4KVW A;  3IBA A;  4JZX A;  4RXC A;  3SAE A;  3PYB A;  3MAV A;  1YV5 A;  4LZC A;  3P5P A;  5B0L A;  1PS1 A;  3ZCD A;  4E1E A;  3P8L A;  3NPK A;  3WCC A;  5HN7 A;  3WCF A;  3M9U A;  3SDU A;  4H5E F;  3WJO A;  2Z4Y A;  5B00 A;  3WEG A;  3LG5 A;  2ZEU A;  4DEM F;  3WCE A;  4JZB A;  3DYG A;  4KQU A;  2P1C A;  2ONH A;  4KKM A;  1YHM A;  1UBY A;  1FPS A;  3WC9 A;  3M00 A;  5ERN A;  4F62 A;  2E90 A;  5HNA A;  2PS4 A;  4PVX F;  3KRA B;  3WCA A;  1VG3 A;  3WEK A;  4LA6 A;  3ACW A;  4LZ3 A;  4OMG A;  4UMJ A;  5H9D A;  2ONG A;  1HM7 A;  2F89 F;  5JV2 F;  2E8U A;  3SDR A;  4H5D F;  3M0G A;  1V4K A;  1YHK A;  3WCM A;  5A0J A;  2F7M F;  3CKE A;  3VJD A;  3N5H F;  5ILY A;  3P5R A;  4F6X A;  1VG4 A;  3V1V A;  5ILH A;  3QQV A;  5EAU A;  4KVD A;  4LFV F;  2F9K F;  4NG6 A;  2O1O A;  2Q58 A;  2AEK A;  4JXY A;  4JYX A;  4MC8 A;  4Q23 A;  3RYE A;  3S4J A;  1YHL A;  5DW7 A;  3WEH A;  3LMD A;  3LJI A;  4DWG A;  1RQI A;  4FP4 A;  2Z4Z A;  3ZOU A;  5C05 A;  1N1B A;  2F8C F;  2E8X A;  3ICM A;  3KRP B;  3VJ8 A;  3VJC A;  1WL1 A;  2AZK A;  5AEL A;  5DZ2 A;  3TFP A;  3LOM A;  5ILI A;  4RXD A;  1N20 A;  5CG6 A;  1JFG A;  1RTR A;  3QKC A;  4N1Z F;  3AQ0 A;  4F6V A;  3EFQ A;  2F94 F; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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