4KWDA

Crystal structure of aspergillus terreus aristolochene synthase complexed with (1r,8r,9as)-1,9a-dimethyl-8-(prop-1-en-2-yl)decahydroquinolizin-5-ium
Total Genus 132
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
132
sequence length
304
structure length
304
Chain Sequence
LEPPPSTFQPLCHPLVEEVSKEVDGYFLQHWNFPNEKARKKFVAAGFSRVTCLYFPKALDDRIHFACRLLTVLFLIDDLLEYMSFEEGSAYNEKLIPISRGDVLPDRSIPVEYIIYDLWESMRAHDREMADEILEPVFLFMRAQTDRTRARPMGLGGYLEYRERDVGKELLAALMRFSMGLKLSPSELQRVREIDANCSKHLSVVNDIYSYEKELYTSKTAHSEGGILCTSVQILAQEADVTAEAAKRVLFVMCREWELRHQLLVARLSAEGLETPGLAAYVEGLEYQMSGNELWSQTTLRYSV
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.


  Genus data interpretation
Chord Diagram
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publication title Mechanistic insights from the binding of substrate and carbocation intermediate analogues to aristolochene synthase.
pubmed doi rcsb
molecule tags Lyase/lyase inhibitor
source organism Aspergillus terreus
molecule keywords Aristolochene synthase
total genus 132
structure length 304
sequence length 304
chains with identical sequence B, C, D
ec nomenclature ec 4.2.3.9: Aristolochene synthase.
pdb deposition date 2013-05-23
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.600.10 Mainly Alpha Orthogonal Bundle Farnesyl Diphosphate Synthase Farnesyl Diphosphate Synthase 4kwdA00
5JV2F 1HXGA 4LZ0A 1YQ7A 3B7LA 4KWDA 3S9VA 5E8HA 4F6XA 2QISA 2VF6A 3M0GA 4MC0A 3N0GA 3AQBB 3EGTA 4JXYA 3ACYA 3P41A 4NKEA 4LZCA 4LIXA 4DWGA 1HX9A 5DHKA 3QKCA 1N23A 3LZ9A 5AFXA 5HN7A 2E92A 4GAXA 4LFVF 2E8UA 1WKZA 3N5HF 3WCLA 3G4FA 4LXWA 4DWBA 1YHKA 5E8LA 4P0XA 1UBYA 1WL0A 2ONHA 3ZMBA 4PVXF 3SDQA 3AQ0A 3LK5A 3KRFA 3QQVA 3IBAA 3P8LA 5IVGA 3DYGA 3Q1OA 5ILZA 4FP4A 3SDTA 2ZCQA 3WEIA 3N5JF 3KRPB 1V4KA 3MZVA 3WCEA 2ZCSA 3APZA 3WEKA 3LEEA 3KRPA 3WEJA 3LGKA 2ZCRA 3OABA 3N1VF 5B0KA 3ADZA 3ID0A 4OGUA 4LTZA 5IL3A 3ACWA 2Z7IA 5H9DA 4H5EF 3PDEA 1YV5A 2H8OA 3DYHA 3M00A 3WJOA 4RYPA 2F94F 3NRIA 5JV1F 1VG7A 4GP2A 4LUUA 3LVSA 4KKMA 4QPFA 3WJKA 3ZL6A 3SAEA 2O1OA 3OACB 2E94A 5IMNA 5B0JA 3CC9A 5DW7A 4F62A 2AELA 4LLSA 3S4JA 3OACA 3WJNA 4JVJF 5EASA 4LZ3A 3ICNA 3ICMA 3TFVA 3N49F 1N20A 4KVIA 4DHDA 3WCIA 1WL2A 3PYBA 3M9UA 5ILYA 4LA5A 2J5CA 3KBKA 3N0FA 3M02A 1RQJA 2E8WA 4H5DF 3WSBA 2Z4WA 3KROA 3WCHA 5CG5A 5JV0F 3N6KF 5B00A 3ICZA 4OKZA 5AYPA 4PVYF 4LOBA 3CKEA 1V4HA 1RTRA 2OPMA 3WCGA 2EWGA 1V4IA 4NFIF 1JFGA 4XQSF 4ZQ8A 2ZEUA 1KIYA 4EA2A 3VJEA 4P0WA 5DZ2A 3OYRA 3N46F 1WY0A 4XQRF 3WCFA 4RXDA 4KPDA 2Z4VA 5B03A 2J1OA 3WCJA 3ZCDA 2Z7HA 2E4OA 2PS8A 3BNXA 3SDRA 1YHMA 3VJAA 2OGDA 1JFAA 3PKOA 2PS6A 5I1UA 3WE9A 3WCCA 1DI1A 5HN9A 3Q2QA 4UMJA 1HXAA 2Z78A 1WL1A 5JUZF 4LPGF 3N3LF 5IKHA 3G4DA 5IMIA 1UBVA 2PS7A 3EFQA 3P5PA 3RYWA 1N1BA 4MC8A 2AZKA 4LFEA 4P0VA 3VJCA 4KQUA 3UCAA 2E8TA 2ZY1A 4LFGA 3N3DA 3PYAA 3NF2A 1YYQA 5ERNA 5C05A 2AZJA 4NG6A 1YYTA 5ILHA 5DJRF 3WEGA 4RXAA 4HD1A 2OPNA 5ER8A 2E95A 3ACXA 3NPKA 3PH7A 4XQTF 4E9ZA 1FPSA 4E1EA 4JZXA 3WCAA 3WC9A 1V4JA 4GP1A 5HN8A 4DI5A 5ILDA 1ZW5A 3MAVA 1YHLA 3M01A 5ERMA 5A0IA 3ICKA 4WK5A 2E8VA 3VJ9A 4Q23A 4OMGA 5B0MA 1VG2A 1N22A 5IK9A 3KRCB 4GA3A 3WEHA 2Q58A 3Q30A 4NFKF 5DHIA 5DGMF 4FJQA 3V1XA 4KQSA 3KRCA 5B0IA 2F89F 2F8ZF 3KRAB 4LA6A 4EA1A 5IL8A 2E93A 4JXNA 5EAUA 5AHUB 4N9UA 2AETA 2Q80A 3P8RA 2RAHA 5AELA 2OA6A 1HXCA 3KRAA 4KVWA 1YYSA 2DH4A 2ONGA 5ILJA 3RYEA 1VG6A 2PS5A 1N24A 5IKAA 1N1ZA 4RXCA 4JZBA 2E8XA 5ILIA 3KB9A 2P1CA 5A0JA 4JYXA 5B02A 2Z52A 2Z50A 5IMPA 3LOMA 3RBMA 1V4EA 4KVYA 3LMDA 2E91A 3W7FA 3AE0A 5IK6A 3P5RA 3RMGA 3LLWA 2E90A 4QXSF 5CG6A 1HM7A 3SDVA 3LDWA 1HM4A 4KPJA 2FTZA 4KQ5A 2ZEVA 2Z4YA 3KRFB 5JA0F 3DYFA 5DGSF 3TFNA 3ZOUA 2F7MF 3VJDA 3TC1A 5DJVF 3LGZB 1UBXA 2Z4XA 3TFPA 4L2XF 4NFJF 5IN8A 3ASXA 2F9KF 3N45F 3WCDA 5E8KA 3OABB 4RXEA 4KFAA 3V66A 3VJBA 3LJIA 1VG4A 2Q9YA 3V1VA 1VG3A 3WCBA 2J1PA 4NKFA 3SDUA 3VJ8A 3Q2ZA 2F92F 4LLTA 1YYUA 5EATA 4E9UA 4OMHA 3TS7A 3BNYA 2ZCOA 2PS4A 4K10A 5DIQF 4RNQA 1UBWA 3WSAA 4OKMA 3CP6A 1PS1A 2FORA 1DGPA 4LPHF 1EZFA 4MC3A 4NUAA 2Q9ZA 4DEMF 4F6VA 2F8CF 1KIZA 2Z4ZA 4DXJA 5DGNF 5IK0A 4DZWA 3NPRA 5IM1A 3ZMCA 1YYRA 1N21A 4EA0A 5KSXF 3N1WF 3WEFA 3LSNA 4KVDA 5HNAA 4LTVA 3LG5A 4KUXA 2AZLA 2I19A 3KROB 5ILKA 4KK2A 5B01A 5B0LA 1RQIA 1WL3A 4H5CF 3WCMA 2AEKA 3IPIA 3EZ3A 1WMWA 3AQCB 5EROA 5A0KA 1YJ4A 4N1ZF 5DJPF
chains in the Genus database with same CATH superfamily
5JV2F 1HXGA 4LZ0A 1YQ7A 3B7LA 4KWDA 3S9VA 5E8HA 4F6XA 2QISA 2VF6A 3M0GA 4MC0A 3N0GA 3AQBB 3EGTA 4JXYA 3ACYA 3P41A 4NKEA 4LZCA 4LIXA 4DWGA 1HX9A 5DHKA 3QKCA 1N23A 3LZ9A 5AFXA 5HN7A 2E92A 4GAXA 4LFVF 2E8UA 1WKZA 3N5HF 3WCLA 3G4FA 4LXWA 4DWBA 1YHKA 5E8LA 4P0XA 1UBYA 1WL0A 2ONHA 3ZMBA 4PVXF 3SDQA 3AQ0A 3LK5A 3KRFA 3QQVA 3IBAA 3P8LA 5IVGA 3DYGA 3Q1OA 5ILZA 4FP4A 3SDTA 2ZCQA 3WEIA 3N5JF 3KRPB 1V4KA 3MZVA 3WCEA 2ZCSA 3APZA 3WEKA 3LEEA 3KRPA 3WEJA 3LGKA 2ZCRA 3OABA 3N1VF 5B0KA 3ADZA 3ID0A 4OGUA 4LTZA 5IL3A 3ACWA 2Z7IA 5H9DA 4H5EF 3PDEA 1YV5A 2H8OA 3DYHA 3M00A 3WJOA 4RYPA 2F94F 3NRIA 5JV1F 1VG7A 4GP2A 4LUUA 3LVSA 4KKMA 4QPFA 3WJKA 3ZL6A 3SAEA 2O1OA 3OACB 2E94A 5IMNA 5B0JA 3CC9A 5DW7A 4F62A 2AELA 4LLSA 3S4JA 3OACA 3WJNA 4JVJF 5EASA 4LZ3A 3ICNA 3ICMA 3TFVA 3N49F 1N20A 4KVIA 4DHDA 3WCIA 1WL2A 3PYBA 3M9UA 5ILYA 4LA5A 2J5CA 3KBKA 3N0FA 3M02A 1RQJA 2E8WA 4H5DF 3WSBA 2Z4WA 3KROA 3WCHA 5CG5A 5JV0F 3N6KF 5B00A 3ICZA 4OKZA 5AYPA 4PVYF 4LOBA 3CKEA 1V4HA 1RTRA 2OPMA 3WCGA 2EWGA 1V4IA 4NFIF 1JFGA 4XQSF 4ZQ8A 2ZEUA 1KIYA 4EA2A 3VJEA 4P0WA 5DZ2A 3OYRA 3N46F 1WY0A 4XQRF 3WCFA 4RXDA 4KPDA 2Z4VA 5B03A 2J1OA 3WCJA 3ZCDA 2Z7HA 2E4OA 2PS8A 3BNXA 3SDRA 1YHMA 3VJAA 2OGDA 1JFAA 3PKOA 2PS6A 5I1UA 3WE9A 3WCCA 1DI1A 5HN9A 3Q2QA 4UMJA 1HXAA 2Z78A 1WL1A 5JUZF 4LPGF 3N3LF 5IKHA 3G4DA 5IMIA 1UBVA 2PS7A 3EFQA 3P5PA 3RYWA 1N1BA 4MC8A 2AZKA 4LFEA 4P0VA 3VJCA 4KQUA 3UCAA 2E8TA 2ZY1A 4LFGA 3N3DA 3PYAA 3NF2A 1YYQA 5ERNA 5C05A 2AZJA 4NG6A 1YYTA 5ILHA 5DJRF 3WEGA 4RXAA 4HD1A 2OPNA 5ER8A 2E95A 3ACXA 3NPKA 3PH7A 4XQTF 4E9ZA 1FPSA 4E1EA 4JZXA 3WCAA 3WC9A 1V4JA 4GP1A 5HN8A 4DI5A 5ILDA 1ZW5A 3MAVA 1YHLA 3M01A 5ERMA 5A0IA 3ICKA 4WK5A 2E8VA 3VJ9A 4Q23A 4OMGA 5B0MA 1VG2A 1N22A 5IK9A 3KRCB 4GA3A 3WEHA 2Q58A 3Q30A 4NFKF 5DHIA 5DGMF 4FJQA 3V1XA 4KQSA 3KRCA 5B0IA 2F89F 2F8ZF 3KRAB 4LA6A 4EA1A 5IL8A 2E93A 4JXNA 5EAUA 5AHUB 4N9UA 2AETA 2Q80A 3P8RA 2RAHA 5AELA 2OA6A 1HXCA 3KRAA 4KVWA 1YYSA 2DH4A 2ONGA 5ILJA 3RYEA 1VG6A 2PS5A 1N24A 5IKAA 1N1ZA 4RXCA 4JZBA 2E8XA 5ILIA 3KB9A 2P1CA 5A0JA 4JYXA 5B02A 2Z52A 2Z50A 5IMPA 3LOMA 3RBMA 1V4EA 4KVYA 3LMDA 2E91A 3W7FA 3AE0A 5IK6A 3P5RA 3RMGA 3LLWA 2E90A 4QXSF 5CG6A 1HM7A 3SDVA 3LDWA 1HM4A 4KPJA 2FTZA 4KQ5A 2ZEVA 2Z4YA 3KRFB 5JA0F 3DYFA 5DGSF 3TFNA 3ZOUA 2F7MF 3VJDA 3TC1A 5DJVF 3LGZB 1UBXA 2Z4XA 3TFPA 4L2XF 4NFJF 5IN8A 3ASXA 2F9KF 3N45F 3WCDA 5E8KA 3OABB 4RXEA 4KFAA 3V66A 3VJBA 3LJIA 1VG4A 2Q9YA 3V1VA 1VG3A 3WCBA 2J1PA 4NKFA 3SDUA 3VJ8A 3Q2ZA 2F92F 4LLTA 1YYUA 5EATA 4E9UA 4OMHA 3TS7A 3BNYA 2ZCOA 2PS4A 4K10A 5DIQF 4RNQA 1UBWA 3WSAA 4OKMA 3CP6A 1PS1A 2FORA 1DGPA 4LPHF 1EZFA 4MC3A 4NUAA 2Q9ZA 4DEMF 4F6VA 2F8CF 1KIZA 2Z4ZA 4DXJA 5DGNF 5IK0A 4DZWA 3NPRA 5IM1A 3ZMCA 1YYRA 1N21A 4EA0A 5KSXF 3N1WF 3WEFA 3LSNA 4KVDA 5HNAA 4LTVA 3LG5A 4KUXA 2AZLA 2I19A 3KROB 5ILKA 4KK2A 5B01A 5B0LA 1RQIA 1WL3A 4H5CF 3WCMA 2AEKA 3IPIA 3EZ3A 1WMWA 3AQCB 5EROA 5A0KA 1YJ4A 4N1ZF 5DJPF
chains in the Genus database with same CATH topology
5JV2F 1HXGA 4LZ0A 1YQ7A 3B7LA 4KWDA 3S9VA 5E8HA 4F6XA 2QISA 2VF6A 3M0GA 4MC0A 3N0GA 3AQBB 3EGTA 4JXYA 3ACYA 3P41A 4NKEA 4LZCA 4LIXA 4DWGA 1HX9A 5DHKA 3QKCA 1N23A 3LZ9A 5AFXA 5HN7A 2E92A 4GAXA 4LFVF 2E8UA 1WKZA 3N5HF 3WCLA 3G4FA 4LXWA 4DWBA 1YHKA 5E8LA 4P0XA 1UBYA 1WL0A 2ONHA 3ZMBA 4PVXF 3SDQA 3AQ0A 3LK5A 3KRFA 3QQVA 3IBAA 3P8LA 5IVGA 3DYGA 3Q1OA 5ILZA 4FP4A 3SDTA 2ZCQA 3WEIA 3N5JF 3KRPB 1V4KA 3MZVA 3WCEA 2ZCSA 3APZA 3WEKA 3LEEA 3KRPA 3WEJA 3LGKA 2ZCRA 3OABA 3N1VF 5B0KA 3ADZA 3ID0A 4OGUA 4LTZA 5IL3A 3ACWA 2Z7IA 5H9DA 4H5EF 3PDEA 1YV5A 2H8OA 3DYHA 3M00A 3WJOA 4RYPA 2F94F 3NRIA 5JV1F 1VG7A 4GP2A 4LUUA 3LVSA 4KKMA 4QPFA 3WJKA 3ZL6A 3SAEA 2O1OA 3OACB 2E94A 5IMNA 5B0JA 3CC9A 5DW7A 4F62A 2AELA 4LLSA 3S4JA 3OACA 3WJNA 4JVJF 5EASA 4LZ3A 3ICNA 3ICMA 3TFVA 3N49F 1N20A 4KVIA 4DHDA 3WCIA 1WL2A 3PYBA 3M9UA 5ILYA 4LA5A 2J5CA 3KBKA 3N0FA 3M02A 1RQJA 2E8WA 4H5DF 3WSBA 2Z4WA 3KROA 3WCHA 5CG5A 5JV0F 3N6KF 5B00A 3ICZA 4OKZA 5AYPA 4PVYF 4LOBA 3CKEA 1V4HA 1RTRA 2OPMA 3WCGA 2EWGA 1V4IA 4NFIF 1JFGA 4XQSF 4ZQ8A 2ZEUA 1KIYA 4EA2A 3VJEA 4P0WA 5DZ2A 3OYRA 3N46F 1WY0A 4XQRF 3WCFA 4RXDA 4KPDA 2Z4VA 5B03A 2J1OA 3WCJA 3ZCDA 2Z7HA 2E4OA 2PS8A 3BNXA 3SDRA 1YHMA 3VJAA 2OGDA 1JFAA 3PKOA 2PS6A 5I1UA 3WE9A 3WCCA 1DI1A 5HN9A 3Q2QA 4UMJA 1HXAA 2Z78A 1WL1A 5JUZF 4LPGF 3N3LF 5IKHA 3G4DA 5IMIA 1UBVA 2PS7A 3EFQA 3P5PA 3RYWA 1N1BA 4MC8A 2AZKA 4LFEA 4P0VA 3VJCA 4KQUA 3UCAA 2E8TA 2ZY1A 4LFGA 3N3DA 3PYAA 3NF2A 1YYQA 5ERNA 5C05A 2AZJA 4NG6A 1YYTA 5ILHA 5DJRF 3WEGA 4RXAA 4HD1A 2OPNA 5ER8A 2E95A 3ACXA 3NPKA 3PH7A 4XQTF 4E9ZA 1FPSA 4E1EA 4JZXA 3WCAA 3WC9A 1V4JA 4GP1A 5HN8A 4DI5A 5ILDA 1ZW5A 3MAVA 1YHLA 3M01A 5ERMA 5A0IA 3ICKA 4WK5A 2E8VA 3VJ9A 4Q23A 4OMGA 5B0MA 1VG2A 1N22A 5IK9A 3KRCB 4GA3A 3WEHA 2Q58A 3Q30A 4NFKF 5DHIA 5DGMF 4FJQA 3V1XA 4KQSA 3KRCA 5B0IA 2F89F 2F8ZF 3KRAB 4LA6A 4EA1A 5IL8A 2E93A 4JXNA 5EAUA 5AHUB 4N9UA 2AETA 2Q80A 3P8RA 2RAHA 5AELA 2OA6A 1HXCA 3KRAA 4KVWA 1YYSA 2DH4A 2ONGA 5ILJA 3RYEA 1VG6A 2PS5A 1N24A 5IKAA 1N1ZA 4RXCA 4JZBA 2E8XA 5ILIA 3KB9A 2P1CA 5A0JA 4JYXA 5B02A 2Z52A 2Z50A 5IMPA 3LOMA 3RBMA 1V4EA 4KVYA 3LMDA 2E91A 3W7FA 3AE0A 5IK6A 3P5RA 3RMGA 3LLWA 2E90A 4QXSF 5CG6A 1HM7A 3SDVA 3LDWA 1HM4A 4KPJA 2FTZA 4KQ5A 2ZEVA 2Z4YA 3KRFB 5JA0F 3DYFA 5DGSF 3TFNA 3ZOUA 2F7MF 3VJDA 3TC1A 5DJVF 3LGZB 1UBXA 2Z4XA 3TFPA 4L2XF 4NFJF 5IN8A 3ASXA 2F9KF 3N45F 3WCDA 5E8KA 3OABB 4RXEA 4KFAA 3V66A 3VJBA 3LJIA 1VG4A 2Q9YA 3V1VA 1VG3A 3WCBA 2J1PA 4NKFA 3SDUA 3VJ8A 3Q2ZA 2F92F 4LLTA 1YYUA 5EATA 4E9UA 4OMHA 3TS7A 3BNYA 2ZCOA 2PS4A 4K10A 5DIQF 4RNQA 1UBWA 3WSAA 4OKMA 3CP6A 1PS1A 2FORA 1DGPA 4LPHF 1EZFA 4MC3A 4NUAA 2Q9ZA 4DEMF 4F6VA 2F8CF 1KIZA 2Z4ZA 4DXJA 5DGNF 5IK0A 4DZWA 3NPRA 5IM1A 3ZMCA 1YYRA 1N21A 4EA0A 5KSXF 3N1WF 3WEFA 3LSNA 4KVDA 5HNAA 4LTVA 3LG5A 4KUXA 2AZLA 2I19A 3KROB 5ILKA 4KK2A 5B01A 5B0LA 1RQIA 1WL3A 4H5CF 3WCMA 2AEKA 3IPIA 3EZ3A 1WMWA 3AQCB 5EROA 5A0KA 1YJ4A 4N1ZF 5DJPF
chains in the Genus database with same CATH homology

  
#chains in the Genus database with same CATH superfamily
 5JV2 F;  1HXG A;  4LZ0 A;  1YQ7 A;  3B7L A;  4KWD A;  3S9V A;  5E8H A;  4F6X A;  2QIS A;  2VF6 A;  3M0G A;  4MC0 A;  3N0G A;  3AQB B;  3EGT A;  4JXY A;  3ACY A;  3P41 A;  4NKE A;  4LZC A;  4LIX A;  4DWG A;  1HX9 A;  5DHK A;  3QKC A;  1N23 A;  3LZ9 A;  5AFX A;  5HN7 A;  2E92 A;  4GAX A;  4LFV F;  2E8U A;  1WKZ A;  3N5H F;  3WCL A;  3G4F A;  4LXW A;  4DWB A;  1YHK A;  5E8L A;  4P0X A;  1UBY A;  1WL0 A;  2ONH A;  3ZMB A;  4PVX F;  3SDQ A;  3AQ0 A;  3LK5 A;  3KRF A;  3QQV A;  3IBA A;  3P8L A;  5IVG A;  3DYG A;  3Q1O A;  5ILZ A;  4FP4 A;  3SDT A;  2ZCQ A;  3WEI A;  3N5J F;  3KRP B;  1V4K A;  3MZV A;  3WCE A;  2ZCS A;  3APZ A;  3WEK A;  3LEE A;  3KRP A;  3WEJ A;  3LGK A;  2ZCR A;  3OAB A;  3N1V F;  5B0K A;  3ADZ A;  3ID0 A;  4OGU A;  4LTZ A;  5IL3 A;  3ACW A;  2Z7I A;  5H9D A;  4H5E F;  3PDE A;  1YV5 A;  2H8O A;  3DYH A;  3M00 A;  3WJO A;  4RYP A;  2F94 F;  3NRI A;  5JV1 F;  1VG7 A;  4GP2 A;  4LUU A;  3LVS A;  4KKM A;  4QPF A;  3WJK A;  3ZL6 A;  3SAE A;  2O1O A;  3OAC B;  2E94 A;  5IMN A;  5B0J A;  3CC9 A;  5DW7 A;  4F62 A;  2AEL A;  4LLS A;  3S4J A;  3OAC A;  3WJN A;  4JVJ F;  5EAS A;  4LZ3 A;  3ICN A;  3ICM A;  3TFV A;  3N49 F;  1N20 A;  4KVI A;  4DHD A;  3WCI A;  1WL2 A;  3PYB A;  3M9U A;  5ILY A;  4LA5 A;  2J5C A;  3KBK A;  3N0F A;  3M02 A;  1RQJ A;  2E8W A;  4H5D F;  3WSB A;  2Z4W A;  3KRO A;  3WCH A;  5CG5 A;  5JV0 F;  3N6K F;  5B00 A;  3ICZ A;  4OKZ A;  5AYP A;  4PVY F;  4LOB A;  3CKE A;  1V4H A;  1RTR A;  2OPM A;  3WCG A;  2EWG A;  1V4I A;  4NFI F;  1JFG A;  4XQS F;  4ZQ8 A;  2ZEU A;  1KIY A;  4EA2 A;  3VJE A;  4P0W A;  5DZ2 A;  3OYR A;  3N46 F;  1WY0 A;  4XQR F;  3WCF A;  4RXD A;  4KPD A;  2Z4V A;  5B03 A;  2J1O A;  3WCJ A;  3ZCD A;  2Z7H A;  2E4O A;  2PS8 A;  3BNX A;  3SDR A;  1YHM A;  3VJA A;  2OGD A;  1JFA A;  3PKO A;  2PS6 A;  5I1U A;  3WE9 A;  3WCC A;  1DI1 A;  5HN9 A;  3Q2Q A;  4UMJ A;  1HXA A;  2Z78 A;  1WL1 A;  5JUZ F;  4LPG F;  3N3L F;  5IKH A;  3G4D A;  5IMI A;  1UBV A;  2PS7 A;  3EFQ A;  3P5P A;  3RYW A;  1N1B A;  4MC8 A;  2AZK A;  4LFE A;  4P0V A;  3VJC A;  4KQU A;  3UCA A;  2E8T A;  2ZY1 A;  4LFG A;  3N3D A;  3PYA A;  3NF2 A;  1YYQ A;  5ERN A;  5C05 A;  2AZJ A;  4NG6 A;  1YYT A;  5ILH A;  5DJR F;  3WEG A;  4RXA A;  4HD1 A;  2OPN A;  5ER8 A;  2E95 A;  3ACX A;  3NPK A;  3PH7 A;  4XQT F;  4E9Z A;  1FPS A;  4E1E A;  4JZX A;  3WCA A;  3WC9 A;  1V4J A;  4GP1 A;  5HN8 A;  4DI5 A;  5ILD A;  1ZW5 A;  3MAV A;  1YHL A;  3M01 A;  5ERM A;  5A0I A;  3ICK A;  4WK5 A;  2E8V A;  3VJ9 A;  4Q23 A;  4OMG A;  5B0M A;  1VG2 A;  1N22 A;  5IK9 A;  3KRC B;  4GA3 A;  3WEH A;  2Q58 A;  3Q30 A;  4NFK F;  5DHI A;  5DGM F;  4FJQ A;  3V1X A;  4KQS A;  3KRC A;  5B0I A;  2F89 F;  2F8Z F;  3KRA B;  4LA6 A;  4EA1 A;  5IL8 A;  2E93 A;  4JXN A;  5EAU A;  5AHU B;  4N9U A;  2AET A;  2Q80 A;  3P8R A;  2RAH A;  5AEL A;  2OA6 A;  1HXC A;  3KRA A;  4KVW A;  1YYS A;  2DH4 A;  2ONG A;  5ILJ A;  3RYE A;  1VG6 A;  2PS5 A;  1N24 A;  5IKA A;  1N1Z A;  4RXC A;  4JZB A;  2E8X A;  5ILI A;  3KB9 A;  2P1C A;  5A0J A;  4JYX A;  5B02 A;  2Z52 A;  2Z50 A;  5IMP A;  3LOM A;  3RBM A;  1V4E A;  4KVY A;  3LMD A;  2E91 A;  3W7F A;  3AE0 A;  5IK6 A;  3P5R A;  3RMG A;  3LLW A;  2E90 A;  4QXS F;  5CG6 A;  1HM7 A;  3SDV A;  3LDW A;  1HM4 A;  4KPJ A;  2FTZ A;  4KQ5 A;  2ZEV A;  2Z4Y A;  3KRF B;  5JA0 F;  3DYF A;  5DGS F;  3TFN A;  3ZOU A;  2F7M F;  3VJD A;  3TC1 A;  5DJV F;  3LGZ B;  1UBX A;  2Z4X A;  3TFP A;  4L2X F;  4NFJ F;  5IN8 A;  3ASX A;  2F9K F;  3N45 F;  3WCD A;  5E8K A;  3OAB B;  4RXE A;  4KFA A;  3V66 A;  3VJB A;  3LJI A;  1VG4 A;  2Q9Y A;  3V1V A;  1VG3 A;  3WCB A;  2J1P A;  4NKF A;  3SDU A;  3VJ8 A;  3Q2Z A;  2F92 F;  4LLT A;  1YYU A;  5EAT A;  4E9U A;  4OMH A;  3TS7 A;  3BNY A;  2ZCO A;  2PS4 A;  4K10 A;  5DIQ F;  4RNQ A;  1UBW A;  3WSA A;  4OKM A;  3CP6 A;  1PS1 A;  2FOR A;  1DGP A;  4LPH F;  1EZF A;  4MC3 A;  4NUA A;  2Q9Z A;  4DEM F;  4F6V A;  2F8C F;  1KIZ A;  2Z4Z A;  4DXJ A;  5DGN F;  5IK0 A;  4DZW A;  3NPR A;  5IM1 A;  3ZMC A;  1YYR A;  1N21 A;  4EA0 A;  5KSX F;  3N1W F;  3WEF A;  3LSN A;  4KVD A;  5HNA A;  4LTV A;  3LG5 A;  4KUX A;  2AZL A;  2I19 A;  3KRO B;  5ILK A;  4KK2 A;  5B01 A;  5B0L A;  1RQI A;  1WL3 A;  4H5C F;  3WCM A;  2AEK A;  3IPI A;  3EZ3 A;  1WMW A;  3AQC B;  5ERO A;  5A0K A;  1YJ4 A;  4N1Z F;  5DJP F; 
#chains in the Genus database with same CATH topology
 5JV2 F;  1HXG A;  4LZ0 A;  1YQ7 A;  3B7L A;  4KWD A;  3S9V A;  5E8H A;  4F6X A;  2QIS A;  2VF6 A;  3M0G A;  4MC0 A;  3N0G A;  3AQB B;  3EGT A;  4JXY A;  3ACY A;  3P41 A;  4NKE A;  4LZC A;  4LIX A;  4DWG A;  1HX9 A;  5DHK A;  3QKC A;  1N23 A;  3LZ9 A;  5AFX A;  5HN7 A;  2E92 A;  4GAX A;  4LFV F;  2E8U A;  1WKZ A;  3N5H F;  3WCL A;  3G4F A;  4LXW A;  4DWB A;  1YHK A;  5E8L A;  4P0X A;  1UBY A;  1WL0 A;  2ONH A;  3ZMB A;  4PVX F;  3SDQ A;  3AQ0 A;  3LK5 A;  3KRF A;  3QQV A;  3IBA A;  3P8L A;  5IVG A;  3DYG A;  3Q1O A;  5ILZ A;  4FP4 A;  3SDT A;  2ZCQ A;  3WEI A;  3N5J F;  3KRP B;  1V4K A;  3MZV A;  3WCE A;  2ZCS A;  3APZ A;  3WEK A;  3LEE A;  3KRP A;  3WEJ A;  3LGK A;  2ZCR A;  3OAB A;  3N1V F;  5B0K A;  3ADZ A;  3ID0 A;  4OGU A;  4LTZ A;  5IL3 A;  3ACW A;  2Z7I A;  5H9D A;  4H5E F;  3PDE A;  1YV5 A;  2H8O A;  3DYH A;  3M00 A;  3WJO A;  4RYP A;  2F94 F;  3NRI A;  5JV1 F;  1VG7 A;  4GP2 A;  4LUU A;  3LVS A;  4KKM A;  4QPF A;  3WJK A;  3ZL6 A;  3SAE A;  2O1O A;  3OAC B;  2E94 A;  5IMN A;  5B0J A;  3CC9 A;  5DW7 A;  4F62 A;  2AEL A;  4LLS A;  3S4J A;  3OAC A;  3WJN A;  4JVJ F;  5EAS A;  4LZ3 A;  3ICN A;  3ICM A;  3TFV A;  3N49 F;  1N20 A;  4KVI A;  4DHD A;  3WCI A;  1WL2 A;  3PYB A;  3M9U A;  5ILY A;  4LA5 A;  2J5C A;  3KBK A;  3N0F A;  3M02 A;  1RQJ A;  2E8W A;  4H5D F;  3WSB A;  2Z4W A;  3KRO A;  3WCH A;  5CG5 A;  5JV0 F;  3N6K F;  5B00 A;  3ICZ A;  4OKZ A;  5AYP A;  4PVY F;  4LOB A;  3CKE A;  1V4H A;  1RTR A;  2OPM A;  3WCG A;  2EWG A;  1V4I A;  4NFI F;  1JFG A;  4XQS F;  4ZQ8 A;  2ZEU A;  1KIY A;  4EA2 A;  3VJE A;  4P0W A;  5DZ2 A;  3OYR A;  3N46 F;  1WY0 A;  4XQR F;  3WCF A;  4RXD A;  4KPD A;  2Z4V A;  5B03 A;  2J1O A;  3WCJ A;  3ZCD A;  2Z7H A;  2E4O A;  2PS8 A;  3BNX A;  3SDR A;  1YHM A;  3VJA A;  2OGD A;  1JFA A;  3PKO A;  2PS6 A;  5I1U A;  3WE9 A;  3WCC A;  1DI1 A;  5HN9 A;  3Q2Q A;  4UMJ A;  1HXA A;  2Z78 A;  1WL1 A;  5JUZ F;  4LPG F;  3N3L F;  5IKH A;  3G4D A;  5IMI A;  1UBV A;  2PS7 A;  3EFQ A;  3P5P A;  3RYW A;  1N1B A;  4MC8 A;  2AZK A;  4LFE A;  4P0V A;  3VJC A;  4KQU A;  3UCA A;  2E8T A;  2ZY1 A;  4LFG A;  3N3D A;  3PYA A;  3NF2 A;  1YYQ A;  5ERN A;  5C05 A;  2AZJ A;  4NG6 A;  1YYT A;  5ILH A;  5DJR F;  3WEG A;  4RXA A;  4HD1 A;  2OPN A;  5ER8 A;  2E95 A;  3ACX A;  3NPK A;  3PH7 A;  4XQT F;  4E9Z A;  1FPS A;  4E1E A;  4JZX A;  3WCA A;  3WC9 A;  1V4J A;  4GP1 A;  5HN8 A;  4DI5 A;  5ILD A;  1ZW5 A;  3MAV A;  1YHL A;  3M01 A;  5ERM A;  5A0I A;  3ICK A;  4WK5 A;  2E8V A;  3VJ9 A;  4Q23 A;  4OMG A;  5B0M A;  1VG2 A;  1N22 A;  5IK9 A;  3KRC B;  4GA3 A;  3WEH A;  2Q58 A;  3Q30 A;  4NFK F;  5DHI A;  5DGM F;  4FJQ A;  3V1X A;  4KQS A;  3KRC A;  5B0I A;  2F89 F;  2F8Z F;  3KRA B;  4LA6 A;  4EA1 A;  5IL8 A;  2E93 A;  4JXN A;  5EAU A;  5AHU B;  4N9U A;  2AET A;  2Q80 A;  3P8R A;  2RAH A;  5AEL A;  2OA6 A;  1HXC A;  3KRA A;  4KVW A;  1YYS A;  2DH4 A;  2ONG A;  5ILJ A;  3RYE A;  1VG6 A;  2PS5 A;  1N24 A;  5IKA A;  1N1Z A;  4RXC A;  4JZB A;  2E8X A;  5ILI A;  3KB9 A;  2P1C A;  5A0J A;  4JYX A;  5B02 A;  2Z52 A;  2Z50 A;  5IMP A;  3LOM A;  3RBM A;  1V4E A;  4KVY A;  3LMD A;  2E91 A;  3W7F A;  3AE0 A;  5IK6 A;  3P5R A;  3RMG A;  3LLW A;  2E90 A;  4QXS F;  5CG6 A;  1HM7 A;  3SDV A;  3LDW A;  1HM4 A;  4KPJ A;  2FTZ A;  4KQ5 A;  2ZEV A;  2Z4Y A;  3KRF B;  5JA0 F;  3DYF A;  5DGS F;  3TFN A;  3ZOU A;  2F7M F;  3VJD A;  3TC1 A;  5DJV F;  3LGZ B;  1UBX A;  2Z4X A;  3TFP A;  4L2X F;  4NFJ F;  5IN8 A;  3ASX A;  2F9K F;  3N45 F;  3WCD A;  5E8K A;  3OAB B;  4RXE A;  4KFA A;  3V66 A;  3VJB A;  3LJI A;  1VG4 A;  2Q9Y A;  3V1V A;  1VG3 A;  3WCB A;  2J1P A;  4NKF A;  3SDU A;  3VJ8 A;  3Q2Z A;  2F92 F;  4LLT A;  1YYU A;  5EAT A;  4E9U A;  4OMH A;  3TS7 A;  3BNY A;  2ZCO A;  2PS4 A;  4K10 A;  5DIQ F;  4RNQ A;  1UBW A;  3WSA A;  4OKM A;  3CP6 A;  1PS1 A;  2FOR A;  1DGP A;  4LPH F;  1EZF A;  4MC3 A;  4NUA A;  2Q9Z A;  4DEM F;  4F6V A;  2F8C F;  1KIZ A;  2Z4Z A;  4DXJ A;  5DGN F;  5IK0 A;  4DZW A;  3NPR A;  5IM1 A;  3ZMC A;  1YYR A;  1N21 A;  4EA0 A;  5KSX F;  3N1W F;  3WEF A;  3LSN A;  4KVD A;  5HNA A;  4LTV A;  3LG5 A;  4KUX A;  2AZL A;  2I19 A;  3KRO B;  5ILK A;  4KK2 A;  5B01 A;  5B0L A;  1RQI A;  1WL3 A;  4H5C F;  3WCM A;  2AEK A;  3IPI A;  3EZ3 A;  1WMW A;  3AQC B;  5ERO A;  5A0K A;  1YJ4 A;  4N1Z F;  5DJP F; 
#chains in the Genus database with same CATH homology
 5JV2 F;  1HXG A;  4LZ0 A;  1YQ7 A;  3B7L A;  4KWD A;  3S9V A;  5E8H A;  4F6X A;  2QIS A;  2VF6 A;  3M0G A;  4MC0 A;  3N0G A;  3AQB B;  3EGT A;  4JXY A;  3ACY A;  3P41 A;  4NKE A;  4LZC A;  4LIX A;  4DWG A;  1HX9 A;  5DHK A;  3QKC A;  1N23 A;  3LZ9 A;  5AFX A;  5HN7 A;  2E92 A;  4GAX A;  4LFV F;  2E8U A;  1WKZ A;  3N5H F;  3WCL A;  3G4F A;  4LXW A;  4DWB A;  1YHK A;  5E8L A;  4P0X A;  1UBY A;  1WL0 A;  2ONH A;  3ZMB A;  4PVX F;  3SDQ A;  3AQ0 A;  3LK5 A;  3KRF A;  3QQV A;  3IBA A;  3P8L A;  5IVG A;  3DYG A;  3Q1O A;  5ILZ A;  4FP4 A;  3SDT A;  2ZCQ A;  3WEI A;  3N5J F;  3KRP B;  1V4K A;  3MZV A;  3WCE A;  2ZCS A;  3APZ A;  3WEK A;  3LEE A;  3KRP A;  3WEJ A;  3LGK A;  2ZCR A;  3OAB A;  3N1V F;  5B0K A;  3ADZ A;  3ID0 A;  4OGU A;  4LTZ A;  5IL3 A;  3ACW A;  2Z7I A;  5H9D A;  4H5E F;  3PDE A;  1YV5 A;  2H8O A;  3DYH A;  3M00 A;  3WJO A;  4RYP A;  2F94 F;  3NRI A;  5JV1 F;  1VG7 A;  4GP2 A;  4LUU A;  3LVS A;  4KKM A;  4QPF A;  3WJK A;  3ZL6 A;  3SAE A;  2O1O A;  3OAC B;  2E94 A;  5IMN A;  5B0J A;  3CC9 A;  5DW7 A;  4F62 A;  2AEL A;  4LLS A;  3S4J A;  3OAC A;  3WJN A;  4JVJ F;  5EAS A;  4LZ3 A;  3ICN A;  3ICM A;  3TFV A;  3N49 F;  1N20 A;  4KVI A;  4DHD A;  3WCI A;  1WL2 A;  3PYB A;  3M9U A;  5ILY A;  4LA5 A;  2J5C A;  3KBK A;  3N0F A;  3M02 A;  1RQJ A;  2E8W A;  4H5D F;  3WSB A;  2Z4W A;  3KRO A;  3WCH A;  5CG5 A;  5JV0 F;  3N6K F;  5B00 A;  3ICZ A;  4OKZ A;  5AYP A;  4PVY F;  4LOB A;  3CKE A;  1V4H A;  1RTR A;  2OPM A;  3WCG A;  2EWG A;  1V4I A;  4NFI F;  1JFG A;  4XQS F;  4ZQ8 A;  2ZEU A;  1KIY A;  4EA2 A;  3VJE A;  4P0W A;  5DZ2 A;  3OYR A;  3N46 F;  1WY0 A;  4XQR F;  3WCF A;  4RXD A;  4KPD A;  2Z4V A;  5B03 A;  2J1O A;  3WCJ A;  3ZCD A;  2Z7H A;  2E4O A;  2PS8 A;  3BNX A;  3SDR A;  1YHM A;  3VJA A;  2OGD A;  1JFA A;  3PKO A;  2PS6 A;  5I1U A;  3WE9 A;  3WCC A;  1DI1 A;  5HN9 A;  3Q2Q A;  4UMJ A;  1HXA A;  2Z78 A;  1WL1 A;  5JUZ F;  4LPG F;  3N3L F;  5IKH A;  3G4D A;  5IMI A;  1UBV A;  2PS7 A;  3EFQ A;  3P5P A;  3RYW A;  1N1B A;  4MC8 A;  2AZK A;  4LFE A;  4P0V A;  3VJC A;  4KQU A;  3UCA A;  2E8T A;  2ZY1 A;  4LFG A;  3N3D A;  3PYA A;  3NF2 A;  1YYQ A;  5ERN A;  5C05 A;  2AZJ A;  4NG6 A;  1YYT A;  5ILH A;  5DJR F;  3WEG A;  4RXA A;  4HD1 A;  2OPN A;  5ER8 A;  2E95 A;  3ACX A;  3NPK A;  3PH7 A;  4XQT F;  4E9Z A;  1FPS A;  4E1E A;  4JZX A;  3WCA A;  3WC9 A;  1V4J A;  4GP1 A;  5HN8 A;  4DI5 A;  5ILD A;  1ZW5 A;  3MAV A;  1YHL A;  3M01 A;  5ERM A;  5A0I A;  3ICK A;  4WK5 A;  2E8V A;  3VJ9 A;  4Q23 A;  4OMG A;  5B0M A;  1VG2 A;  1N22 A;  5IK9 A;  3KRC B;  4GA3 A;  3WEH A;  2Q58 A;  3Q30 A;  4NFK F;  5DHI A;  5DGM F;  4FJQ A;  3V1X A;  4KQS A;  3KRC A;  5B0I A;  2F89 F;  2F8Z F;  3KRA B;  4LA6 A;  4EA1 A;  5IL8 A;  2E93 A;  4JXN A;  5EAU A;  5AHU B;  4N9U A;  2AET A;  2Q80 A;  3P8R A;  2RAH A;  5AEL A;  2OA6 A;  1HXC A;  3KRA A;  4KVW A;  1YYS A;  2DH4 A;  2ONG A;  5ILJ A;  3RYE A;  1VG6 A;  2PS5 A;  1N24 A;  5IKA A;  1N1Z A;  4RXC A;  4JZB A;  2E8X A;  5ILI A;  3KB9 A;  2P1C A;  5A0J A;  4JYX A;  5B02 A;  2Z52 A;  2Z50 A;  5IMP A;  3LOM A;  3RBM A;  1V4E A;  4KVY A;  3LMD A;  2E91 A;  3W7F A;  3AE0 A;  5IK6 A;  3P5R A;  3RMG A;  3LLW A;  2E90 A;  4QXS F;  5CG6 A;  1HM7 A;  3SDV A;  3LDW A;  1HM4 A;  4KPJ A;  2FTZ A;  4KQ5 A;  2ZEV A;  2Z4Y A;  3KRF B;  5JA0 F;  3DYF A;  5DGS F;  3TFN A;  3ZOU A;  2F7M F;  3VJD A;  3TC1 A;  5DJV F;  3LGZ B;  1UBX A;  2Z4X A;  3TFP A;  4L2X F;  4NFJ F;  5IN8 A;  3ASX A;  2F9K F;  3N45 F;  3WCD A;  5E8K A;  3OAB B;  4RXE A;  4KFA A;  3V66 A;  3VJB A;  3LJI A;  1VG4 A;  2Q9Y A;  3V1V A;  1VG3 A;  3WCB A;  2J1P A;  4NKF A;  3SDU A;  3VJ8 A;  3Q2Z A;  2F92 F;  4LLT A;  1YYU A;  5EAT A;  4E9U A;  4OMH A;  3TS7 A;  3BNY A;  2ZCO A;  2PS4 A;  4K10 A;  5DIQ F;  4RNQ A;  1UBW A;  3WSA A;  4OKM A;  3CP6 A;  1PS1 A;  2FOR A;  1DGP A;  4LPH F;  1EZF A;  4MC3 A;  4NUA A;  2Q9Z A;  4DEM F;  4F6V A;  2F8C F;  1KIZ A;  2Z4Z A;  4DXJ A;  5DGN F;  5IK0 A;  4DZW A;  3NPR A;  5IM1 A;  3ZMC A;  1YYR A;  1N21 A;  4EA0 A;  5KSX F;  3N1W F;  3WEF A;  3LSN A;  4KVD A;  5HNA A;  4LTV A;  3LG5 A;  4KUX A;  2AZL A;  2I19 A;  3KRO B;  5ILK A;  4KK2 A;  5B01 A;  5B0L A;  1RQI A;  1WL3 A;  4H5C F;  3WCM A;  2AEK A;  3IPI A;  3EZ3 A;  1WMW A;  3AQC B;  5ERO A;  5A0K A;  1YJ4 A;  4N1Z F;  5DJP F;
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

  
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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