4LXWA

L72v epi-isozizaene synthase: complex with mg, inorganic pyrophosphate and benzyl triethyl ammonium cation
Total Genus 150
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
150
sequence length
340
structure length
340
Chain Sequence
AVPPSLRLPVIEAAFPRQLHPYWPKLQETTRTWLLEKRLMPADKVEEYADGLCYTDVMAGYYLGAPDEVLQAIADYSAWFFVWDDRHDRDIVHGRAGAWRRLRGLLHTALDSPGDHLHHEDTLVAGFADSVRRLYAFLPATWNARFARHFHTVIEAYDREFHNRTRGIVPGVEEYLELRRLTFAHWIWTDLLEPSSGCELPDAVRKHPAYRRAALLSQEFAAWYNDLCSLPKEIAGDEVHNLGISLITHHSLTLEEAIGEVRRRVEECITEFLAVERDALRFADELADGTVRGKELSGAVRANVGNMRNWFSSVYWFHHESGRYMVDSWDDRSTPPYVNN
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Reprogramming the Chemodiversity of Terpenoid Cyclization by Remolding the Active Site Contour of epi-Isozizaene Synthase.
pubmed doi rcsb
molecule tags Lyase
source organism Streptomyces coelicolor
molecule keywords Epi-isozizaene synthase
total genus 150
structure length 340
sequence length 340
ec nomenclature ec 4.2.3.37: Epi-isozizaene synthase.
pdb deposition date 2013-07-30
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.600.10 Mainly Alpha Orthogonal Bundle Farnesyl Diphosphate Synthase Farnesyl Diphosphate Synthase 4lxwA00
4KKMA 5KSXF 4LPHF 2P1CA 2Q9ZA 5IMNA 4OKMA 1RQIA 2E8WA 1VG6A 3CKEA 2E8TA 4KVWA 4LLTA 2AZKA 4JXYA 3V1VA 4KFAA 5E8HA 3N0GA 3OACB 3DYFA 3KRPB 2Z50A 4F62A 1RQJA 5DW7A 5AHUB 2ZCRA 1YHKA 2J1PA 3VJEA 3WEIA 2PS7A 4LTVA 5ERNA 5B0KA 4LOBA 3G4DA 2VF6A 4KPJA 3CC9A 5B01A 5ILYA 4N1ZF 3ICMA 4LXWA 4OMHA 3TS7A 4JZBA 4K10A 4LZ3A 2AZLA 5JA0F 3LK5A 1WY0A 3KROB 3WEKA 3WEGA 5A0IA 5IK9A 2AETA 3Q2ZA 2F9KF 3PYBA 3TFNA 3P41A 3G4FA 2F94F 3RYWA 1N1ZA 3BNYA 3OACA 2F8ZF 3BNXA 3WCGA 3WCJA 3NF2A 1N1BA 3KRPA 4E9UA 3LMDA 4QPFA 4DXJA 3EZ3A 5DJVF 4XQTF 4DWBA 4NFIF 3M02A 5IN8A 4KVYA 3PYAA 2I19A 3ZOUA 2ZY1A 3APZA 3ZL6A 5AYPA 3M00A 3OYRA 2ONHA 1YHMA 5ILHA 5ILZA 3N6KF 3WE9A 4F6VA 4XQSF 3RBMA 1WKZA 4JYXA 2QISA 3SDUA 2EWGA 1JFGA 2J1OA 3VJDA 2H8OA 4PVYF 2E8VA 3AQCB 3LJIA 5IL3A 5B0IA 5IM1A 5A0KA 3P5RA 4KQ5A 3ACYA 3ICZA 4NG6A 1HM7A 4LA6A 4E9ZA 2E8XA 4DZWA 4FP4A 1VG7A 3WC9A 4JXNA 4RYPA 2DH4A 3RMGA 1YYRA 3N1WF 1ZW5A 5IKHA 3WCEA 2ZEVA 3WSBA 5ERMA 4DEMF 3WCIA 1RTRA 2ZEUA 3NRIA 5B02A 1UBWA 3N3DA 5ILDA 4GA3A 2PS6A 3VJAA 1UBVA 5DJPF 1KIYA 5JV0F 1N22A 3LEEA 3IPIA 2E91A 5HN8A 3SAEA 4QXSF 1N21A 3M0GA 4KQUA 3TFVA 3LOMA 4JZXA 3LGKA 2Z78A 4EA0A 1PS1A 3V66A 3ACWA 3WEFA 4KPDA 3DYHA 5H9DA 2AZJA 3Q2QA 1N23A 3N5JF 3N0FA 1WL3A 5IK0A 1WL2A 2F92F 3N3LF 4GP1A 2E94A 4LFEA 3TFPA 3NPRA 3WEHA 3WJNA 3P5PA 3MAVA 2AEKA 1HX9A 3LDWA 4KK2A 2Z52A 4LZ0A 3WCMA 2Z4VA 4ZQ8A 5EAUA 3ZMBA 3NPKA 4KUXA 5IMPA 4DWGA 3WCLA 5DGSF 3IBAA 4LUUA 3QQVA 4RXDA 5CG5A 3TC1A 5I1UA 5JV1F 5DGNF 3MZVA 3WCBA 3WJOA 3PDEA 5E8LA 4Q23A 4NFKF 4KWDA 4JVJF 4L2XF 2OPNA 1YYQA 3WJKA 4LLSA 3VJ9A 5ILKA 1N20A 2ZCQA 3Q30A 3LZ9A 2FORA 3OABB 3N45F 3KBKA 1VG3A 4LFGA 5DHIA 1V4KA 5ILJA 3PKOA 2J5CA 2Z4YA 3WCDA 1EZFA 1WMWA 3WCFA 5ER8A 5B0MA 1HXAA 4RXCA 2ZCSA 1VG2A 3P8RA 4EA1A 3AQ0A 3CP6A 5IVGA 3ASXA 3M01A 4OMGA 5B00A 4LPGF 5C05A 5DJRF 4LFVF 5DIQF 5IK6A 1YYTA 3N1VF 3WEJA 3ZMCA 5EATA 4RXAA 4GAXA 3N46F 2Z4WA 3WCAA 4MC3A 3KRFA 4FJQA 4KVIA 3VJ8A 2ONGA 3KB9A 3DYGA 3P8LA 4DHDA 3OABA 4P0XA 5IMIA 4E1EA 3B7LA 2PS5A 3KRCB 4LA5A 2Q58A 2Z7IA 4MC8A 4NUAA 2F89F 1DGPA 5EASA 4DI5A 2Z4XA 4PVXF 2OA6A 5IL8A 3SDTA 4H5DF 5AFXA 4HD1A 4P0VA 3EGTA 5B0LA 2OGDA 3PH7A 4H5CF 1YQ7A 1YYUA 4KVDA 3ICKA 1WL1A 3VJCA 4OGUA 5HNAA 3M9UA 4KQSA 3RYEA 5ILIA 1KIZA 4RXEA 3Q1OA 5DZ2A 3ADZA 2PS4A 1YHLA 3AE0A 3UCAA 4GP2A 4H5EF 2E95A 3KRCA 4RNQA 4LIXA 2ZCOA 2Q80A 5E8KA 2FTZA 3KRAB 1WL0A 3QKCA 4LZCA 5DHKA 2E90A 1UBXA 3ACXA 2F7MF 1FPSA 1V4HA 3S9VA 2OPMA 2E92A 3KRFB 4XQRF 5DGMF 3SDRA 4NFJF 4LTZA 3SDQA 3WCCA 3V1XA 2PS8A 4MC0A 5B03A 5B0JA 3LGZB 4WK5A 1N24A 5A0JA 4NKFA 5AELA 1YV5A 3LSNA 1HXCA 2F8CF 4OKZA 2E93A 4N9UA 1JFAA 5EROA 2E4OA 1V4JA 3WSAA 2Q9YA 3KROA 3VJBA 1DI1A 1HXGA 3LLWA 3KRAA 1YJ4A 3EFQA 3ID0A 3LG5A 3N5HF 5JV2F 3SDVA 3AQBB 2RAHA 3ICNA 1V4EA 1V4IA 1YYSA 3N49F 3LVSA 2AELA 5IKAA 5HN7A 4P0WA 1VG4A 5CG6A 3W7FA 2E8UA 2O1OA 5JUZF 3S4JA 1UBYA 3WCHA 4NKEA 4UMJA 3ZCDA 2Z4ZA 1HM4A 2Z7HA 4F6XA 5HN9A 4EA2A
chains in the Genus database with same CATH superfamily
4KKMA 5KSXF 4LPHF 2P1CA 2Q9ZA 5IMNA 4OKMA 1RQIA 2E8WA 1VG6A 3CKEA 2E8TA 4KVWA 4LLTA 2AZKA 4JXYA 3V1VA 4KFAA 5E8HA 3N0GA 3OACB 3DYFA 3KRPB 2Z50A 4F62A 1RQJA 5DW7A 5AHUB 2ZCRA 1YHKA 2J1PA 3VJEA 3WEIA 2PS7A 4LTVA 5ERNA 5B0KA 4LOBA 3G4DA 2VF6A 4KPJA 3CC9A 5B01A 5ILYA 4N1ZF 3ICMA 4LXWA 4OMHA 3TS7A 4JZBA 4K10A 4LZ3A 2AZLA 5JA0F 3LK5A 1WY0A 3KROB 3WEKA 3WEGA 5A0IA 5IK9A 2AETA 3Q2ZA 2F9KF 3PYBA 3TFNA 3P41A 3G4FA 2F94F 3RYWA 1N1ZA 3BNYA 3OACA 2F8ZF 3BNXA 3WCGA 3WCJA 3NF2A 1N1BA 3KRPA 4E9UA 3LMDA 4QPFA 4DXJA 3EZ3A 5DJVF 4XQTF 4DWBA 4NFIF 3M02A 5IN8A 4KVYA 3PYAA 2I19A 3ZOUA 2ZY1A 3APZA 3ZL6A 5AYPA 3M00A 3OYRA 2ONHA 1YHMA 5ILHA 5ILZA 3N6KF 3WE9A 4F6VA 4XQSF 3RBMA 1WKZA 4JYXA 2QISA 3SDUA 2EWGA 1JFGA 2J1OA 3VJDA 2H8OA 4PVYF 2E8VA 3AQCB 3LJIA 5IL3A 5B0IA 5IM1A 5A0KA 3P5RA 4KQ5A 3ACYA 3ICZA 4NG6A 1HM7A 4LA6A 4E9ZA 2E8XA 4DZWA 4FP4A 1VG7A 3WC9A 4JXNA 4RYPA 2DH4A 3RMGA 1YYRA 3N1WF 1ZW5A 5IKHA 3WCEA 2ZEVA 3WSBA 5ERMA 4DEMF 3WCIA 1RTRA 2ZEUA 3NRIA 5B02A 1UBWA 3N3DA 5ILDA 4GA3A 2PS6A 3VJAA 1UBVA 5DJPF 1KIYA 5JV0F 1N22A 3LEEA 3IPIA 2E91A 5HN8A 3SAEA 4QXSF 1N21A 3M0GA 4KQUA 3TFVA 3LOMA 4JZXA 3LGKA 2Z78A 4EA0A 1PS1A 3V66A 3ACWA 3WEFA 4KPDA 3DYHA 5H9DA 2AZJA 3Q2QA 1N23A 3N5JF 3N0FA 1WL3A 5IK0A 1WL2A 2F92F 3N3LF 4GP1A 2E94A 4LFEA 3TFPA 3NPRA 3WEHA 3WJNA 3P5PA 3MAVA 2AEKA 1HX9A 3LDWA 4KK2A 2Z52A 4LZ0A 3WCMA 2Z4VA 4ZQ8A 5EAUA 3ZMBA 3NPKA 4KUXA 5IMPA 4DWGA 3WCLA 5DGSF 3IBAA 4LUUA 3QQVA 4RXDA 5CG5A 3TC1A 5I1UA 5JV1F 5DGNF 3MZVA 3WCBA 3WJOA 3PDEA 5E8LA 4Q23A 4NFKF 4KWDA 4JVJF 4L2XF 2OPNA 1YYQA 3WJKA 4LLSA 3VJ9A 5ILKA 1N20A 2ZCQA 3Q30A 3LZ9A 2FORA 3OABB 3N45F 3KBKA 1VG3A 4LFGA 5DHIA 1V4KA 5ILJA 3PKOA 2J5CA 2Z4YA 3WCDA 1EZFA 1WMWA 3WCFA 5ER8A 5B0MA 1HXAA 4RXCA 2ZCSA 1VG2A 3P8RA 4EA1A 3AQ0A 3CP6A 5IVGA 3ASXA 3M01A 4OMGA 5B00A 4LPGF 5C05A 5DJRF 4LFVF 5DIQF 5IK6A 1YYTA 3N1VF 3WEJA 3ZMCA 5EATA 4RXAA 4GAXA 3N46F 2Z4WA 3WCAA 4MC3A 3KRFA 4FJQA 4KVIA 3VJ8A 2ONGA 3KB9A 3DYGA 3P8LA 4DHDA 3OABA 4P0XA 5IMIA 4E1EA 3B7LA 2PS5A 3KRCB 4LA5A 2Q58A 2Z7IA 4MC8A 4NUAA 2F89F 1DGPA 5EASA 4DI5A 2Z4XA 4PVXF 2OA6A 5IL8A 3SDTA 4H5DF 5AFXA 4HD1A 4P0VA 3EGTA 5B0LA 2OGDA 3PH7A 4H5CF 1YQ7A 1YYUA 4KVDA 3ICKA 1WL1A 3VJCA 4OGUA 5HNAA 3M9UA 4KQSA 3RYEA 5ILIA 1KIZA 4RXEA 3Q1OA 5DZ2A 3ADZA 2PS4A 1YHLA 3AE0A 3UCAA 4GP2A 4H5EF 2E95A 3KRCA 4RNQA 4LIXA 2ZCOA 2Q80A 5E8KA 2FTZA 3KRAB 1WL0A 3QKCA 4LZCA 5DHKA 2E90A 1UBXA 3ACXA 2F7MF 1FPSA 1V4HA 3S9VA 2OPMA 2E92A 3KRFB 4XQRF 5DGMF 3SDRA 4NFJF 4LTZA 3SDQA 3WCCA 3V1XA 2PS8A 4MC0A 5B03A 5B0JA 3LGZB 4WK5A 1N24A 5A0JA 4NKFA 5AELA 1YV5A 3LSNA 1HXCA 2F8CF 4OKZA 2E93A 4N9UA 1JFAA 5EROA 2E4OA 1V4JA 3WSAA 2Q9YA 3KROA 3VJBA 1DI1A 1HXGA 3LLWA 3KRAA 1YJ4A 3EFQA 3ID0A 3LG5A 3N5HF 5JV2F 3SDVA 3AQBB 2RAHA 3ICNA 1V4EA 1V4IA 1YYSA 3N49F 3LVSA 2AELA 5IKAA 5HN7A 4P0WA 1VG4A 5CG6A 3W7FA 2E8UA 2O1OA 5JUZF 3S4JA 1UBYA 3WCHA 4NKEA 4UMJA 3ZCDA 2Z4ZA 1HM4A 2Z7HA 4F6XA 5HN9A 4EA2A
chains in the Genus database with same CATH topology
4KKMA 5KSXF 4LPHF 2P1CA 2Q9ZA 5IMNA 4OKMA 1RQIA 2E8WA 1VG6A 3CKEA 2E8TA 4KVWA 4LLTA 2AZKA 4JXYA 3V1VA 4KFAA 5E8HA 3N0GA 3OACB 3DYFA 3KRPB 2Z50A 4F62A 1RQJA 5DW7A 5AHUB 2ZCRA 1YHKA 2J1PA 3VJEA 3WEIA 2PS7A 4LTVA 5ERNA 5B0KA 4LOBA 3G4DA 2VF6A 4KPJA 3CC9A 5B01A 5ILYA 4N1ZF 3ICMA 4LXWA 4OMHA 3TS7A 4JZBA 4K10A 4LZ3A 2AZLA 5JA0F 3LK5A 1WY0A 3KROB 3WEKA 3WEGA 5A0IA 5IK9A 2AETA 3Q2ZA 2F9KF 3PYBA 3TFNA 3P41A 3G4FA 2F94F 3RYWA 1N1ZA 3BNYA 3OACA 2F8ZF 3BNXA 3WCGA 3WCJA 3NF2A 1N1BA 3KRPA 4E9UA 3LMDA 4QPFA 4DXJA 3EZ3A 5DJVF 4XQTF 4DWBA 4NFIF 3M02A 5IN8A 4KVYA 3PYAA 2I19A 3ZOUA 2ZY1A 3APZA 3ZL6A 5AYPA 3M00A 3OYRA 2ONHA 1YHMA 5ILHA 5ILZA 3N6KF 3WE9A 4F6VA 4XQSF 3RBMA 1WKZA 4JYXA 2QISA 3SDUA 2EWGA 1JFGA 2J1OA 3VJDA 2H8OA 4PVYF 2E8VA 3AQCB 3LJIA 5IL3A 5B0IA 5IM1A 5A0KA 3P5RA 4KQ5A 3ACYA 3ICZA 4NG6A 1HM7A 4LA6A 4E9ZA 2E8XA 4DZWA 4FP4A 1VG7A 3WC9A 4JXNA 4RYPA 2DH4A 3RMGA 1YYRA 3N1WF 1ZW5A 5IKHA 3WCEA 2ZEVA 3WSBA 5ERMA 4DEMF 3WCIA 1RTRA 2ZEUA 3NRIA 5B02A 1UBWA 3N3DA 5ILDA 4GA3A 2PS6A 3VJAA 1UBVA 5DJPF 1KIYA 5JV0F 1N22A 3LEEA 3IPIA 2E91A 5HN8A 3SAEA 4QXSF 1N21A 3M0GA 4KQUA 3TFVA 3LOMA 4JZXA 3LGKA 2Z78A 4EA0A 1PS1A 3V66A 3ACWA 3WEFA 4KPDA 3DYHA 5H9DA 2AZJA 3Q2QA 1N23A 3N5JF 3N0FA 1WL3A 5IK0A 1WL2A 2F92F 3N3LF 4GP1A 2E94A 4LFEA 3TFPA 3NPRA 3WEHA 3WJNA 3P5PA 3MAVA 2AEKA 1HX9A 3LDWA 4KK2A 2Z52A 4LZ0A 3WCMA 2Z4VA 4ZQ8A 5EAUA 3ZMBA 3NPKA 4KUXA 5IMPA 4DWGA 3WCLA 5DGSF 3IBAA 4LUUA 3QQVA 4RXDA 5CG5A 3TC1A 5I1UA 5JV1F 5DGNF 3MZVA 3WCBA 3WJOA 3PDEA 5E8LA 4Q23A 4NFKF 4KWDA 4JVJF 4L2XF 2OPNA 1YYQA 3WJKA 4LLSA 3VJ9A 5ILKA 1N20A 2ZCQA 3Q30A 3LZ9A 2FORA 3OABB 3N45F 3KBKA 1VG3A 4LFGA 5DHIA 1V4KA 5ILJA 3PKOA 2J5CA 2Z4YA 3WCDA 1EZFA 1WMWA 3WCFA 5ER8A 5B0MA 1HXAA 4RXCA 2ZCSA 1VG2A 3P8RA 4EA1A 3AQ0A 3CP6A 5IVGA 3ASXA 3M01A 4OMGA 5B00A 4LPGF 5C05A 5DJRF 4LFVF 5DIQF 5IK6A 1YYTA 3N1VF 3WEJA 3ZMCA 5EATA 4RXAA 4GAXA 3N46F 2Z4WA 3WCAA 4MC3A 3KRFA 4FJQA 4KVIA 3VJ8A 2ONGA 3KB9A 3DYGA 3P8LA 4DHDA 3OABA 4P0XA 5IMIA 4E1EA 3B7LA 2PS5A 3KRCB 4LA5A 2Q58A 2Z7IA 4MC8A 4NUAA 2F89F 1DGPA 5EASA 4DI5A 2Z4XA 4PVXF 2OA6A 5IL8A 3SDTA 4H5DF 5AFXA 4HD1A 4P0VA 3EGTA 5B0LA 2OGDA 3PH7A 4H5CF 1YQ7A 1YYUA 4KVDA 3ICKA 1WL1A 3VJCA 4OGUA 5HNAA 3M9UA 4KQSA 3RYEA 5ILIA 1KIZA 4RXEA 3Q1OA 5DZ2A 3ADZA 2PS4A 1YHLA 3AE0A 3UCAA 4GP2A 4H5EF 2E95A 3KRCA 4RNQA 4LIXA 2ZCOA 2Q80A 5E8KA 2FTZA 3KRAB 1WL0A 3QKCA 4LZCA 5DHKA 2E90A 1UBXA 3ACXA 2F7MF 1FPSA 1V4HA 3S9VA 2OPMA 2E92A 3KRFB 4XQRF 5DGMF 3SDRA 4NFJF 4LTZA 3SDQA 3WCCA 3V1XA 2PS8A 4MC0A 5B03A 5B0JA 3LGZB 4WK5A 1N24A 5A0JA 4NKFA 5AELA 1YV5A 3LSNA 1HXCA 2F8CF 4OKZA 2E93A 4N9UA 1JFAA 5EROA 2E4OA 1V4JA 3WSAA 2Q9YA 3KROA 3VJBA 1DI1A 1HXGA 3LLWA 3KRAA 1YJ4A 3EFQA 3ID0A 3LG5A 3N5HF 5JV2F 3SDVA 3AQBB 2RAHA 3ICNA 1V4EA 1V4IA 1YYSA 3N49F 3LVSA 2AELA 5IKAA 5HN7A 4P0WA 1VG4A 5CG6A 3W7FA 2E8UA 2O1OA 5JUZF 3S4JA 1UBYA 3WCHA 4NKEA 4UMJA 3ZCDA 2Z4ZA 1HM4A 2Z7HA 4F6XA 5HN9A 4EA2A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4KKM A;  5KSX F;  4LPH F;  2P1C A;  2Q9Z A;  5IMN A;  4OKM A;  1RQI A;  2E8W A;  1VG6 A;  3CKE A;  2E8T A;  4KVW A;  4LLT A;  2AZK A;  4JXY A;  3V1V A;  4KFA A;  5E8H A;  3N0G A;  3OAC B;  3DYF A;  3KRP B;  2Z50 A;  4F62 A;  1RQJ A;  5DW7 A;  5AHU B;  2ZCR A;  1YHK A;  2J1P A;  3VJE A;  3WEI A;  2PS7 A;  4LTV A;  5ERN A;  5B0K A;  4LOB A;  3G4D A;  2VF6 A;  4KPJ A;  3CC9 A;  5B01 A;  5ILY A;  4N1Z F;  3ICM A;  4LXW A;  4OMH A;  3TS7 A;  4JZB A;  4K10 A;  4LZ3 A;  2AZL A;  5JA0 F;  3LK5 A;  1WY0 A;  3KRO B;  3WEK A;  3WEG A;  5A0I A;  5IK9 A;  2AET A;  3Q2Z A;  2F9K F;  3PYB A;  3TFN A;  3P41 A;  3G4F A;  2F94 F;  3RYW A;  1N1Z A;  3BNY A;  3OAC A;  2F8Z F;  3BNX A;  3WCG A;  3WCJ A;  3NF2 A;  1N1B A;  3KRP A;  4E9U A;  3LMD A;  4QPF A;  4DXJ A;  3EZ3 A;  5DJV F;  4XQT F;  4DWB A;  4NFI F;  3M02 A;  5IN8 A;  4KVY A;  3PYA A;  2I19 A;  3ZOU A;  2ZY1 A;  3APZ A;  3ZL6 A;  5AYP A;  3M00 A;  3OYR A;  2ONH A;  1YHM A;  5ILH A;  5ILZ A;  3N6K F;  3WE9 A;  4F6V A;  4XQS F;  3RBM A;  1WKZ A;  4JYX A;  2QIS A;  3SDU A;  2EWG A;  1JFG A;  2J1O A;  3VJD A;  2H8O A;  4PVY F;  2E8V A;  3AQC B;  3LJI A;  5IL3 A;  5B0I A;  5IM1 A;  5A0K A;  3P5R A;  4KQ5 A;  3ACY A;  3ICZ A;  4NG6 A;  1HM7 A;  4LA6 A;  4E9Z A;  2E8X A;  4DZW A;  4FP4 A;  1VG7 A;  3WC9 A;  4JXN A;  4RYP A;  2DH4 A;  3RMG A;  1YYR A;  3N1W F;  1ZW5 A;  5IKH A;  3WCE A;  2ZEV A;  3WSB A;  5ERM A;  4DEM F;  3WCI A;  1RTR A;  2ZEU A;  3NRI A;  5B02 A;  1UBW A;  3N3D A;  5ILD A;  4GA3 A;  2PS6 A;  3VJA A;  1UBV A;  5DJP F;  1KIY A;  5JV0 F;  1N22 A;  3LEE A;  3IPI A;  2E91 A;  5HN8 A;  3SAE A;  4QXS F;  1N21 A;  3M0G A;  4KQU A;  3TFV A;  3LOM A;  4JZX A;  3LGK A;  2Z78 A;  4EA0 A;  1PS1 A;  3V66 A;  3ACW A;  3WEF A;  4KPD A;  3DYH A;  5H9D A;  2AZJ A;  3Q2Q A;  1N23 A;  3N5J F;  3N0F A;  1WL3 A;  5IK0 A;  1WL2 A;  2F92 F;  3N3L F;  4GP1 A;  2E94 A;  4LFE A;  3TFP A;  3NPR A;  3WEH A;  3WJN A;  3P5P A;  3MAV A;  2AEK A;  1HX9 A;  3LDW A;  4KK2 A;  2Z52 A;  4LZ0 A;  3WCM A;  2Z4V A;  4ZQ8 A;  5EAU A;  3ZMB A;  3NPK A;  4KUX A;  5IMP A;  4DWG A;  3WCL A;  5DGS F;  3IBA A;  4LUU A;  3QQV A;  4RXD A;  5CG5 A;  3TC1 A;  5I1U A;  5JV1 F;  5DGN F;  3MZV A;  3WCB A;  3WJO A;  3PDE A;  5E8L A;  4Q23 A;  4NFK F;  4KWD A;  4JVJ F;  4L2X F;  2OPN A;  1YYQ A;  3WJK A;  4LLS A;  3VJ9 A;  5ILK A;  1N20 A;  2ZCQ A;  3Q30 A;  3LZ9 A;  2FOR A;  3OAB B;  3N45 F;  3KBK A;  1VG3 A;  4LFG A;  5DHI A;  1V4K A;  5ILJ A;  3PKO A;  2J5C A;  2Z4Y A;  3WCD A;  1EZF A;  1WMW A;  3WCF A;  5ER8 A;  5B0M A;  1HXA A;  4RXC A;  2ZCS A;  1VG2 A;  3P8R A;  4EA1 A;  3AQ0 A;  3CP6 A;  5IVG A;  3ASX A;  3M01 A;  4OMG A;  5B00 A;  4LPG F;  5C05 A;  5DJR F;  4LFV F;  5DIQ F;  5IK6 A;  1YYT A;  3N1V F;  3WEJ A;  3ZMC A;  5EAT A;  4RXA A;  4GAX A;  3N46 F;  2Z4W A;  3WCA A;  4MC3 A;  3KRF A;  4FJQ A;  4KVI A;  3VJ8 A;  2ONG A;  3KB9 A;  3DYG A;  3P8L A;  4DHD A;  3OAB A;  4P0X A;  5IMI A;  4E1E A;  3B7L A;  2PS5 A;  3KRC B;  4LA5 A;  2Q58 A;  2Z7I A;  4MC8 A;  4NUA A;  2F89 F;  1DGP A;  5EAS A;  4DI5 A;  2Z4X A;  4PVX F;  2OA6 A;  5IL8 A;  3SDT A;  4H5D F;  5AFX A;  4HD1 A;  4P0V A;  3EGT A;  5B0L A;  2OGD A;  3PH7 A;  4H5C F;  1YQ7 A;  1YYU A;  4KVD A;  3ICK A;  1WL1 A;  3VJC A;  4OGU A;  5HNA A;  3M9U A;  4KQS A;  3RYE A;  5ILI A;  1KIZ A;  4RXE A;  3Q1O A;  5DZ2 A;  3ADZ A;  2PS4 A;  1YHL A;  3AE0 A;  3UCA A;  4GP2 A;  4H5E F;  2E95 A;  3KRC A;  4RNQ A;  4LIX A;  2ZCO A;  2Q80 A;  5E8K A;  2FTZ A;  3KRA B;  1WL0 A;  3QKC A;  4LZC A;  5DHK A;  2E90 A;  1UBX A;  3ACX A;  2F7M F;  1FPS A;  1V4H A;  3S9V A;  2OPM A;  2E92 A;  3KRF B;  4XQR F;  5DGM F;  3SDR A;  4NFJ F;  4LTZ A;  3SDQ A;  3WCC A;  3V1X A;  2PS8 A;  4MC0 A;  5B03 A;  5B0J A;  3LGZ B;  4WK5 A;  1N24 A;  5A0J A;  4NKF A;  5AEL A;  1YV5 A;  3LSN A;  1HXC A;  2F8C F;  4OKZ A;  2E93 A;  4N9U A;  1JFA A;  5ERO A;  2E4O A;  1V4J A;  3WSA A;  2Q9Y A;  3KRO A;  3VJB A;  1DI1 A;  1HXG A;  3LLW A;  3KRA A;  1YJ4 A;  3EFQ A;  3ID0 A;  3LG5 A;  3N5H F;  5JV2 F;  3SDV A;  3AQB B;  2RAH A;  3ICN A;  1V4E A;  1V4I A;  1YYS A;  3N49 F;  3LVS A;  2AEL A;  5IKA A;  5HN7 A;  4P0W A;  1VG4 A;  5CG6 A;  3W7F A;  2E8U A;  2O1O A;  5JUZ F;  3S4J A;  1UBY A;  3WCH A;  4NKE A;  4UMJ A;  3ZCD A;  2Z4Z A;  1HM4 A;  2Z7H A;  4F6X A;  5HN9 A;  4EA2 A; 
#chains in the Genus database with same CATH topology
 4KKM A;  5KSX F;  4LPH F;  2P1C A;  2Q9Z A;  5IMN A;  4OKM A;  1RQI A;  2E8W A;  1VG6 A;  3CKE A;  2E8T A;  4KVW A;  4LLT A;  2AZK A;  4JXY A;  3V1V A;  4KFA A;  5E8H A;  3N0G A;  3OAC B;  3DYF A;  3KRP B;  2Z50 A;  4F62 A;  1RQJ A;  5DW7 A;  5AHU B;  2ZCR A;  1YHK A;  2J1P A;  3VJE A;  3WEI A;  2PS7 A;  4LTV A;  5ERN A;  5B0K A;  4LOB A;  3G4D A;  2VF6 A;  4KPJ A;  3CC9 A;  5B01 A;  5ILY A;  4N1Z F;  3ICM A;  4LXW A;  4OMH A;  3TS7 A;  4JZB A;  4K10 A;  4LZ3 A;  2AZL A;  5JA0 F;  3LK5 A;  1WY0 A;  3KRO B;  3WEK A;  3WEG A;  5A0I A;  5IK9 A;  2AET A;  3Q2Z A;  2F9K F;  3PYB A;  3TFN A;  3P41 A;  3G4F A;  2F94 F;  3RYW A;  1N1Z A;  3BNY A;  3OAC A;  2F8Z F;  3BNX A;  3WCG A;  3WCJ A;  3NF2 A;  1N1B A;  3KRP A;  4E9U A;  3LMD A;  4QPF A;  4DXJ A;  3EZ3 A;  5DJV F;  4XQT F;  4DWB A;  4NFI F;  3M02 A;  5IN8 A;  4KVY A;  3PYA A;  2I19 A;  3ZOU A;  2ZY1 A;  3APZ A;  3ZL6 A;  5AYP A;  3M00 A;  3OYR A;  2ONH A;  1YHM A;  5ILH A;  5ILZ A;  3N6K F;  3WE9 A;  4F6V A;  4XQS F;  3RBM A;  1WKZ A;  4JYX A;  2QIS A;  3SDU A;  2EWG A;  1JFG A;  2J1O A;  3VJD A;  2H8O A;  4PVY F;  2E8V A;  3AQC B;  3LJI A;  5IL3 A;  5B0I A;  5IM1 A;  5A0K A;  3P5R A;  4KQ5 A;  3ACY A;  3ICZ A;  4NG6 A;  1HM7 A;  4LA6 A;  4E9Z A;  2E8X A;  4DZW A;  4FP4 A;  1VG7 A;  3WC9 A;  4JXN A;  4RYP A;  2DH4 A;  3RMG A;  1YYR A;  3N1W F;  1ZW5 A;  5IKH A;  3WCE A;  2ZEV A;  3WSB A;  5ERM A;  4DEM F;  3WCI A;  1RTR A;  2ZEU A;  3NRI A;  5B02 A;  1UBW A;  3N3D A;  5ILD A;  4GA3 A;  2PS6 A;  3VJA A;  1UBV A;  5DJP F;  1KIY A;  5JV0 F;  1N22 A;  3LEE A;  3IPI A;  2E91 A;  5HN8 A;  3SAE A;  4QXS F;  1N21 A;  3M0G A;  4KQU A;  3TFV A;  3LOM A;  4JZX A;  3LGK A;  2Z78 A;  4EA0 A;  1PS1 A;  3V66 A;  3ACW A;  3WEF A;  4KPD A;  3DYH A;  5H9D A;  2AZJ A;  3Q2Q A;  1N23 A;  3N5J F;  3N0F A;  1WL3 A;  5IK0 A;  1WL2 A;  2F92 F;  3N3L F;  4GP1 A;  2E94 A;  4LFE A;  3TFP A;  3NPR A;  3WEH A;  3WJN A;  3P5P A;  3MAV A;  2AEK A;  1HX9 A;  3LDW A;  4KK2 A;  2Z52 A;  4LZ0 A;  3WCM A;  2Z4V A;  4ZQ8 A;  5EAU A;  3ZMB A;  3NPK A;  4KUX A;  5IMP A;  4DWG A;  3WCL A;  5DGS F;  3IBA A;  4LUU A;  3QQV A;  4RXD A;  5CG5 A;  3TC1 A;  5I1U A;  5JV1 F;  5DGN F;  3MZV A;  3WCB A;  3WJO A;  3PDE A;  5E8L A;  4Q23 A;  4NFK F;  4KWD A;  4JVJ F;  4L2X F;  2OPN A;  1YYQ A;  3WJK A;  4LLS A;  3VJ9 A;  5ILK A;  1N20 A;  2ZCQ A;  3Q30 A;  3LZ9 A;  2FOR A;  3OAB B;  3N45 F;  3KBK A;  1VG3 A;  4LFG A;  5DHI A;  1V4K A;  5ILJ A;  3PKO A;  2J5C A;  2Z4Y A;  3WCD A;  1EZF A;  1WMW A;  3WCF A;  5ER8 A;  5B0M A;  1HXA A;  4RXC A;  2ZCS A;  1VG2 A;  3P8R A;  4EA1 A;  3AQ0 A;  3CP6 A;  5IVG A;  3ASX A;  3M01 A;  4OMG A;  5B00 A;  4LPG F;  5C05 A;  5DJR F;  4LFV F;  5DIQ F;  5IK6 A;  1YYT A;  3N1V F;  3WEJ A;  3ZMC A;  5EAT A;  4RXA A;  4GAX A;  3N46 F;  2Z4W A;  3WCA A;  4MC3 A;  3KRF A;  4FJQ A;  4KVI A;  3VJ8 A;  2ONG A;  3KB9 A;  3DYG A;  3P8L A;  4DHD A;  3OAB A;  4P0X A;  5IMI A;  4E1E A;  3B7L A;  2PS5 A;  3KRC B;  4LA5 A;  2Q58 A;  2Z7I A;  4MC8 A;  4NUA A;  2F89 F;  1DGP A;  5EAS A;  4DI5 A;  2Z4X A;  4PVX F;  2OA6 A;  5IL8 A;  3SDT A;  4H5D F;  5AFX A;  4HD1 A;  4P0V A;  3EGT A;  5B0L A;  2OGD A;  3PH7 A;  4H5C F;  1YQ7 A;  1YYU A;  4KVD A;  3ICK A;  1WL1 A;  3VJC A;  4OGU A;  5HNA A;  3M9U A;  4KQS A;  3RYE A;  5ILI A;  1KIZ A;  4RXE A;  3Q1O A;  5DZ2 A;  3ADZ A;  2PS4 A;  1YHL A;  3AE0 A;  3UCA A;  4GP2 A;  4H5E F;  2E95 A;  3KRC A;  4RNQ A;  4LIX A;  2ZCO A;  2Q80 A;  5E8K A;  2FTZ A;  3KRA B;  1WL0 A;  3QKC A;  4LZC A;  5DHK A;  2E90 A;  1UBX A;  3ACX A;  2F7M F;  1FPS A;  1V4H A;  3S9V A;  2OPM A;  2E92 A;  3KRF B;  4XQR F;  5DGM F;  3SDR A;  4NFJ F;  4LTZ A;  3SDQ A;  3WCC A;  3V1X A;  2PS8 A;  4MC0 A;  5B03 A;  5B0J A;  3LGZ B;  4WK5 A;  1N24 A;  5A0J A;  4NKF A;  5AEL A;  1YV5 A;  3LSN A;  1HXC A;  2F8C F;  4OKZ A;  2E93 A;  4N9U A;  1JFA A;  5ERO A;  2E4O A;  1V4J A;  3WSA A;  2Q9Y A;  3KRO A;  3VJB A;  1DI1 A;  1HXG A;  3LLW A;  3KRA A;  1YJ4 A;  3EFQ A;  3ID0 A;  3LG5 A;  3N5H F;  5JV2 F;  3SDV A;  3AQB B;  2RAH A;  3ICN A;  1V4E A;  1V4I A;  1YYS A;  3N49 F;  3LVS A;  2AEL A;  5IKA A;  5HN7 A;  4P0W A;  1VG4 A;  5CG6 A;  3W7F A;  2E8U A;  2O1O A;  5JUZ F;  3S4J A;  1UBY A;  3WCH A;  4NKE A;  4UMJ A;  3ZCD A;  2Z4Z A;  1HM4 A;  2Z7H A;  4F6X A;  5HN9 A;  4EA2 A; 
#chains in the Genus database with same CATH homology
 4KKM A;  5KSX F;  4LPH F;  2P1C A;  2Q9Z A;  5IMN A;  4OKM A;  1RQI A;  2E8W A;  1VG6 A;  3CKE A;  2E8T A;  4KVW A;  4LLT A;  2AZK A;  4JXY A;  3V1V A;  4KFA A;  5E8H A;  3N0G A;  3OAC B;  3DYF A;  3KRP B;  2Z50 A;  4F62 A;  1RQJ A;  5DW7 A;  5AHU B;  2ZCR A;  1YHK A;  2J1P A;  3VJE A;  3WEI A;  2PS7 A;  4LTV A;  5ERN A;  5B0K A;  4LOB A;  3G4D A;  2VF6 A;  4KPJ A;  3CC9 A;  5B01 A;  5ILY A;  4N1Z F;  3ICM A;  4LXW A;  4OMH A;  3TS7 A;  4JZB A;  4K10 A;  4LZ3 A;  2AZL A;  5JA0 F;  3LK5 A;  1WY0 A;  3KRO B;  3WEK A;  3WEG A;  5A0I A;  5IK9 A;  2AET A;  3Q2Z A;  2F9K F;  3PYB A;  3TFN A;  3P41 A;  3G4F A;  2F94 F;  3RYW A;  1N1Z A;  3BNY A;  3OAC A;  2F8Z F;  3BNX A;  3WCG A;  3WCJ A;  3NF2 A;  1N1B A;  3KRP A;  4E9U A;  3LMD A;  4QPF A;  4DXJ A;  3EZ3 A;  5DJV F;  4XQT F;  4DWB A;  4NFI F;  3M02 A;  5IN8 A;  4KVY A;  3PYA A;  2I19 A;  3ZOU A;  2ZY1 A;  3APZ A;  3ZL6 A;  5AYP A;  3M00 A;  3OYR A;  2ONH A;  1YHM A;  5ILH A;  5ILZ A;  3N6K F;  3WE9 A;  4F6V A;  4XQS F;  3RBM A;  1WKZ A;  4JYX A;  2QIS A;  3SDU A;  2EWG A;  1JFG A;  2J1O A;  3VJD A;  2H8O A;  4PVY F;  2E8V A;  3AQC B;  3LJI A;  5IL3 A;  5B0I A;  5IM1 A;  5A0K A;  3P5R A;  4KQ5 A;  3ACY A;  3ICZ A;  4NG6 A;  1HM7 A;  4LA6 A;  4E9Z A;  2E8X A;  4DZW A;  4FP4 A;  1VG7 A;  3WC9 A;  4JXN A;  4RYP A;  2DH4 A;  3RMG A;  1YYR A;  3N1W F;  1ZW5 A;  5IKH A;  3WCE A;  2ZEV A;  3WSB A;  5ERM A;  4DEM F;  3WCI A;  1RTR A;  2ZEU A;  3NRI A;  5B02 A;  1UBW A;  3N3D A;  5ILD A;  4GA3 A;  2PS6 A;  3VJA A;  1UBV A;  5DJP F;  1KIY A;  5JV0 F;  1N22 A;  3LEE A;  3IPI A;  2E91 A;  5HN8 A;  3SAE A;  4QXS F;  1N21 A;  3M0G A;  4KQU A;  3TFV A;  3LOM A;  4JZX A;  3LGK A;  2Z78 A;  4EA0 A;  1PS1 A;  3V66 A;  3ACW A;  3WEF A;  4KPD A;  3DYH A;  5H9D A;  2AZJ A;  3Q2Q A;  1N23 A;  3N5J F;  3N0F A;  1WL3 A;  5IK0 A;  1WL2 A;  2F92 F;  3N3L F;  4GP1 A;  2E94 A;  4LFE A;  3TFP A;  3NPR A;  3WEH A;  3WJN A;  3P5P A;  3MAV A;  2AEK A;  1HX9 A;  3LDW A;  4KK2 A;  2Z52 A;  4LZ0 A;  3WCM A;  2Z4V A;  4ZQ8 A;  5EAU A;  3ZMB A;  3NPK A;  4KUX A;  5IMP A;  4DWG A;  3WCL A;  5DGS F;  3IBA A;  4LUU A;  3QQV A;  4RXD A;  5CG5 A;  3TC1 A;  5I1U A;  5JV1 F;  5DGN F;  3MZV A;  3WCB A;  3WJO A;  3PDE A;  5E8L A;  4Q23 A;  4NFK F;  4KWD A;  4JVJ F;  4L2X F;  2OPN A;  1YYQ A;  3WJK A;  4LLS A;  3VJ9 A;  5ILK A;  1N20 A;  2ZCQ A;  3Q30 A;  3LZ9 A;  2FOR A;  3OAB B;  3N45 F;  3KBK A;  1VG3 A;  4LFG A;  5DHI A;  1V4K A;  5ILJ A;  3PKO A;  2J5C A;  2Z4Y A;  3WCD A;  1EZF A;  1WMW A;  3WCF A;  5ER8 A;  5B0M A;  1HXA A;  4RXC A;  2ZCS A;  1VG2 A;  3P8R A;  4EA1 A;  3AQ0 A;  3CP6 A;  5IVG A;  3ASX A;  3M01 A;  4OMG A;  5B00 A;  4LPG F;  5C05 A;  5DJR F;  4LFV F;  5DIQ F;  5IK6 A;  1YYT A;  3N1V F;  3WEJ A;  3ZMC A;  5EAT A;  4RXA A;  4GAX A;  3N46 F;  2Z4W A;  3WCA A;  4MC3 A;  3KRF A;  4FJQ A;  4KVI A;  3VJ8 A;  2ONG A;  3KB9 A;  3DYG A;  3P8L A;  4DHD A;  3OAB A;  4P0X A;  5IMI A;  4E1E A;  3B7L A;  2PS5 A;  3KRC B;  4LA5 A;  2Q58 A;  2Z7I A;  4MC8 A;  4NUA A;  2F89 F;  1DGP A;  5EAS A;  4DI5 A;  2Z4X A;  4PVX F;  2OA6 A;  5IL8 A;  3SDT A;  4H5D F;  5AFX A;  4HD1 A;  4P0V A;  3EGT A;  5B0L A;  2OGD A;  3PH7 A;  4H5C F;  1YQ7 A;  1YYU A;  4KVD A;  3ICK A;  1WL1 A;  3VJC A;  4OGU A;  5HNA A;  3M9U A;  4KQS A;  3RYE A;  5ILI A;  1KIZ A;  4RXE A;  3Q1O A;  5DZ2 A;  3ADZ A;  2PS4 A;  1YHL A;  3AE0 A;  3UCA A;  4GP2 A;  4H5E F;  2E95 A;  3KRC A;  4RNQ A;  4LIX A;  2ZCO A;  2Q80 A;  5E8K A;  2FTZ A;  3KRA B;  1WL0 A;  3QKC A;  4LZC A;  5DHK A;  2E90 A;  1UBX A;  3ACX A;  2F7M F;  1FPS A;  1V4H A;  3S9V A;  2OPM A;  2E92 A;  3KRF B;  4XQR F;  5DGM F;  3SDR A;  4NFJ F;  4LTZ A;  3SDQ A;  3WCC A;  3V1X A;  2PS8 A;  4MC0 A;  5B03 A;  5B0J A;  3LGZ B;  4WK5 A;  1N24 A;  5A0J A;  4NKF A;  5AEL A;  1YV5 A;  3LSN A;  1HXC A;  2F8C F;  4OKZ A;  2E93 A;  4N9U A;  1JFA A;  5ERO A;  2E4O A;  1V4J A;  3WSA A;  2Q9Y A;  3KRO A;  3VJB A;  1DI1 A;  1HXG A;  3LLW A;  3KRA A;  1YJ4 A;  3EFQ A;  3ID0 A;  3LG5 A;  3N5H F;  5JV2 F;  3SDV A;  3AQB B;  2RAH A;  3ICN A;  1V4E A;  1V4I A;  1YYS A;  3N49 F;  3LVS A;  2AEL A;  5IKA A;  5HN7 A;  4P0W A;  1VG4 A;  5CG6 A;  3W7F A;  2E8U A;  2O1O A;  5JUZ F;  3S4J A;  1UBY A;  3WCH A;  4NKE A;  4UMJ A;  3ZCD A;  2Z4Z A;  1HM4 A;  2Z7H A;  4F6X A;  5HN9 A;  4EA2 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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