4RXEA

T. brucei farnesyl diphosphate synthase complexed with bisphosphonate bph-14
Total Genus 151
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
151
sequence length
367
structure length
358
Chain Sequence
MPMQMFMQVYDEIQMFLLEELELKFDMDPNRVRYLRKMMDTTCLGGKYNRGLTVIDVAESLLSLDGARRKRVLHDACVCGWMIEFLQAHYLVEDDIMDNSVTRRGKPCWYRHPDVTVQCAINDGLLLKSWTHMMAMHFFADRPFLQDLLCRFNRVDYTTAVGQLYDVTSMFDSNKLDPDVSQPTTTDFAEFTLSNYKRIVKYKTAYYTYLLPLVMGLIVSEALPTVDMGVTEELAMLMGEYFQVQDDVMDCFTPPERLGKVGTDIQDAKCSWLAVTFLAKASSAQVAEFKANYGSGDSEKVATVRRLYEEADLQGDYVAYEAAVAEQVKELIEKLRLCSPGFAASVETLWGKTYKRQK
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Farnesyl diphosphate synthase inhibitors with unique ligand-binding geometries.
pubmed doi rcsb
molecule tags Transferase/transferase inhibitor
source organism Trypanosoma brucei
molecule keywords Farnesyl pyrophosphate synthase
total genus 151
structure length 358
sequence length 367
chains with identical sequence B
ec nomenclature
pdb deposition date 2014-12-10

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00348 polyprenyl_synt Polyprenyl synthetase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.600.10 Mainly Alpha Orthogonal Bundle Farnesyl Diphosphate Synthase Farnesyl Diphosphate Synthase 4rxeA00
2E93A 3ICZA 2F8ZF 3RYWA 3S9VA 1HXAA 4Q23A 3WEFA 2E90A 5B0IA 5B03A 2E91A 5DGMF 3SDTA 4XQSF 5H9DA 3S4JA 3WCGA 3P8LA 3WSAA 2VF6A 3KB9A 1WKZA 5I1UA 2Z4XA 3MAVA 3NPRA 1PS1A 2E92A 3RBMA 2DH4A 3WCFA 4DWGA 5CG5A 5DJVF 2PS8A 5HN8A 3KRFA 4KQ5A 3LDWA 4LPGF 4EA1A 5JV1F 3WEHA 2Q80A 2ZEVA 3ZCDA 1WY0A 3CC9A 3NPKA 4MC8A 1DI1A 1WL0A 4NKFA 3EZ3A 1WL2A 5A0JA 5ILKA 3KRCA 1V4JA 2F7MF 3WCCA 4JZXA 4GA3A 5DZ2A 4KFAA 4F6XA 4KKMA 3LVSA 5B0KA 1UBYA 1JFAA 4H5CF 5IL3A 3OYRA 2Z52A 1UBVA 3LK5A 3N3LF 5B0JA 5B0MA 5IKAA 5IN8A 5HNAA 5B0LA 1HX9A 3VJ8A 4PVXF 2EWGA 3WE9A 2Q9YA 3KRFB 5KSXF 3EFQA 2Z4VA 4KPJA 3KROB 3DYHA 4LA6A 4ZQ8A 4JVJF 3ACWA 4GP2A 5E8LA 2Z4WA 5DJRF 3N46F 1YHMA 3IBAA 3ICKA 3WEGA 5DGSF 5JA0F 4RXCA 4DWBA 2O1OA 4RXEA 3RYEA 1YQ7A 2FORA 5IMPA 3WJOA 3NRIA 5DJPF 3N1WF 4MC3A 2E4OA 2FTZA 3B7LA 3LJIA 3AE0A 4DI5A 4JXNA 3ASXA 4GAXA 2AEKA 3DYGA 3TS7A 1WL1A 4LZ3A 1N1ZA 4N1ZF 2PS5A 3CP6A 1VG3A 5JV0F 4LTZA 3ZL6A 5HN9A 3LOMA 5ILDA 3ICMA 5AELA 4P0XA 3LZ9A 1ZW5A 3N49F 3P41A 1WL3A 2F92F 3M02A 3SDRA 1YYSA 3PYBA 2PS6A 4JZBA 1RQJA 4NG6A 4F62A 5IL8A 4LTVA 3Q1OA 3Q30A 3V1VA 5EAUA 3ICNA 1HM4A 5DIQF 4EA0A 1HXCA 3WCIA 3V66A 3WCDA 4DHDA 5JUZF 1N21A 3N6KF 1HM7A 2E95A 4H5EF 3ADZA 5IMIA 1DGPA 3AQCB 3KRPA 5DW7A 5EASA 2I19A 2OPNA 4LFGA 1V4KA 5EATA 3WCHA 4OMGA 4LOBA 3MZVA 4NUAA 3WCBA 2ZCQA 5ER8A 1VG2A 3Q2QA 1YYRA 4KUXA 1VG6A 4DXJA 3LEEA 5E8HA 5DGNF 4LA5A 5AFXA 3Q2ZA 2Z4YA 3N45F 1YV5A 3ACXA 2E94A 3LSNA 4NFIF 4KVIA 2Z7IA 1VG7A 2AZKA 2J1OA 2Z4ZA 2E8WA 4XQRF 3LLWA 3OABA 2RAHA 4H5DF 3RMGA 4LFVF 3KRAA 3WSBA 1V4IA 4P0WA 3WCMA 3WJKA 3N0FA 2ZCRA 3PYAA 4OMHA 4NKEA 4E9ZA 5ILJA 3M9UA 3P5PA 2Z50A 3KRPB 1YYQA 2E8UA 3OACA 1YYTA 3ZMBA 4DZWA 3VJDA 5IKHA 4HD1A 2ZCSA 3N5JF 2AETA 4XQTF 1KIYA 3KRCB 2AELA 5DHIA 5CG6A 2Q58A 4OKMA 3QQVA 2ZY1A 2ZEUA 4JXYA 4LZCA 1YYUA 4MC0A 3BNXA 3IPIA 3VJBA 3SDQA 5ILYA 4PVYF 2OPMA 2AZJA 2E8XA 4RNQA 1YJ4A 2E8TA 4OKZA 1RTRA 2J1PA 4GP1A 4EA2A 3OABB 3PDEA 3VJEA 3KRAB 5AYPA 3TFNA 4LPHF 1N23A 1VG4A 3VJ9A 3TC1A 1UBWA 2F8CF 5DHKA 3TFVA 3TFPA 3N3DA 3OACB 1V4EA 5A0KA 4KQSA 3SDVA 1N22A 4DEMF 5C05A 2H8OA 3V1XA 4NFKF 3DYFA 3WJNA 4FJQA 3WCAA 1FPSA 3WCEA 5ERNA 3M0GA 2J5CA 4LIXA 3N5HF 3WEIA 4OGUA 3LMDA 3BNYA 4RXAA 3ID0A 3M00A 4KPDA 4L2XF 4KVYA 1KIZA 5IK0A 2E8VA 3LGZB 5A0IA 3N1VF 3LG5A 3VJAA 4K10A 3SAEA 3KROA 3PH7A 2Q9ZA 2ONGA 4KWDA 4WK5A 2OA6A 5JV2F 3WC9A 5EROA 2F9KF 3WEKA 3ZOUA 5IK6A 3AQBB 4P0VA 2AZLA 3NF2A 1EZFA 4LLSA 4KQUA 5B02A 1UBXA 3N0GA 5ILHA 2QISA 4JYXA 4FP4A 3EGTA 4LUUA 5IMNA 4KK2A 2PS7A 2F89F 4NFJF 3AQ0A 3WCJA 3WEJA 3P8RA 3QKCA 4RYPA 3WCLA 2PS4A 3G4DA 3PKOA 3LGKA 3UCAA 5ILZA 3APZA 5B00A 1JFGA 4QXSF 5IM1A 3SDUA 3M01A 2OGDA 5B01A 4LXWA 3CKEA 1WMWA 4E9UA 1YHLA 5IVGA 4QPFA 4LFEA 4N9UA 1N20A 3G4FA 3VJCA 2P1CA 1N24A 4KVDA 2ONHA 3W7FA 5ILIA 4LZ0A 5E8KA 4F6VA 4UMJA 2Z7HA 2ZCOA 4RXDA 4E1EA 5HN7A 4LLTA 2F94F 3ZMCA 1HXGA 3KBKA 4KVWA 1RQIA 5AHUB 2Z78A 3P5RA 5IK9A 5ERMA 1V4HA 1YHKA 1N1BA 3ACYA
chains in the Genus database with same CATH superfamily
2E93A 3ICZA 2F8ZF 3RYWA 3S9VA 1HXAA 4Q23A 3WEFA 2E90A 5B0IA 5B03A 2E91A 5DGMF 3SDTA 4XQSF 5H9DA 3S4JA 3WCGA 3P8LA 3WSAA 2VF6A 3KB9A 1WKZA 5I1UA 2Z4XA 3MAVA 3NPRA 1PS1A 2E92A 3RBMA 2DH4A 3WCFA 4DWGA 5CG5A 5DJVF 2PS8A 5HN8A 3KRFA 4KQ5A 3LDWA 4LPGF 4EA1A 5JV1F 3WEHA 2Q80A 2ZEVA 3ZCDA 1WY0A 3CC9A 3NPKA 4MC8A 1DI1A 1WL0A 4NKFA 3EZ3A 1WL2A 5A0JA 5ILKA 3KRCA 1V4JA 2F7MF 3WCCA 4JZXA 4GA3A 5DZ2A 4KFAA 4F6XA 4KKMA 3LVSA 5B0KA 1UBYA 1JFAA 4H5CF 5IL3A 3OYRA 2Z52A 1UBVA 3LK5A 3N3LF 5B0JA 5B0MA 5IKAA 5IN8A 5HNAA 5B0LA 1HX9A 3VJ8A 4PVXF 2EWGA 3WE9A 2Q9YA 3KRFB 5KSXF 3EFQA 2Z4VA 4KPJA 3KROB 3DYHA 4LA6A 4ZQ8A 4JVJF 3ACWA 4GP2A 5E8LA 2Z4WA 5DJRF 3N46F 1YHMA 3IBAA 3ICKA 3WEGA 5DGSF 5JA0F 4RXCA 4DWBA 2O1OA 4RXEA 3RYEA 1YQ7A 2FORA 5IMPA 3WJOA 3NRIA 5DJPF 3N1WF 4MC3A 2E4OA 2FTZA 3B7LA 3LJIA 3AE0A 4DI5A 4JXNA 3ASXA 4GAXA 2AEKA 3DYGA 3TS7A 1WL1A 4LZ3A 1N1ZA 4N1ZF 2PS5A 3CP6A 1VG3A 5JV0F 4LTZA 3ZL6A 5HN9A 3LOMA 5ILDA 3ICMA 5AELA 4P0XA 3LZ9A 1ZW5A 3N49F 3P41A 1WL3A 2F92F 3M02A 3SDRA 1YYSA 3PYBA 2PS6A 4JZBA 1RQJA 4NG6A 4F62A 5IL8A 4LTVA 3Q1OA 3Q30A 3V1VA 5EAUA 3ICNA 1HM4A 5DIQF 4EA0A 1HXCA 3WCIA 3V66A 3WCDA 4DHDA 5JUZF 1N21A 3N6KF 1HM7A 2E95A 4H5EF 3ADZA 5IMIA 1DGPA 3AQCB 3KRPA 5DW7A 5EASA 2I19A 2OPNA 4LFGA 1V4KA 5EATA 3WCHA 4OMGA 4LOBA 3MZVA 4NUAA 3WCBA 2ZCQA 5ER8A 1VG2A 3Q2QA 1YYRA 4KUXA 1VG6A 4DXJA 3LEEA 5E8HA 5DGNF 4LA5A 5AFXA 3Q2ZA 2Z4YA 3N45F 1YV5A 3ACXA 2E94A 3LSNA 4NFIF 4KVIA 2Z7IA 1VG7A 2AZKA 2J1OA 2Z4ZA 2E8WA 4XQRF 3LLWA 3OABA 2RAHA 4H5DF 3RMGA 4LFVF 3KRAA 3WSBA 1V4IA 4P0WA 3WCMA 3WJKA 3N0FA 2ZCRA 3PYAA 4OMHA 4NKEA 4E9ZA 5ILJA 3M9UA 3P5PA 2Z50A 3KRPB 1YYQA 2E8UA 3OACA 1YYTA 3ZMBA 4DZWA 3VJDA 5IKHA 4HD1A 2ZCSA 3N5JF 2AETA 4XQTF 1KIYA 3KRCB 2AELA 5DHIA 5CG6A 2Q58A 4OKMA 3QQVA 2ZY1A 2ZEUA 4JXYA 4LZCA 1YYUA 4MC0A 3BNXA 3IPIA 3VJBA 3SDQA 5ILYA 4PVYF 2OPMA 2AZJA 2E8XA 4RNQA 1YJ4A 2E8TA 4OKZA 1RTRA 2J1PA 4GP1A 4EA2A 3OABB 3PDEA 3VJEA 3KRAB 5AYPA 3TFNA 4LPHF 1N23A 1VG4A 3VJ9A 3TC1A 1UBWA 2F8CF 5DHKA 3TFVA 3TFPA 3N3DA 3OACB 1V4EA 5A0KA 4KQSA 3SDVA 1N22A 4DEMF 5C05A 2H8OA 3V1XA 4NFKF 3DYFA 3WJNA 4FJQA 3WCAA 1FPSA 3WCEA 5ERNA 3M0GA 2J5CA 4LIXA 3N5HF 3WEIA 4OGUA 3LMDA 3BNYA 4RXAA 3ID0A 3M00A 4KPDA 4L2XF 4KVYA 1KIZA 5IK0A 2E8VA 3LGZB 5A0IA 3N1VF 3LG5A 3VJAA 4K10A 3SAEA 3KROA 3PH7A 2Q9ZA 2ONGA 4KWDA 4WK5A 2OA6A 5JV2F 3WC9A 5EROA 2F9KF 3WEKA 3ZOUA 5IK6A 3AQBB 4P0VA 2AZLA 3NF2A 1EZFA 4LLSA 4KQUA 5B02A 1UBXA 3N0GA 5ILHA 2QISA 4JYXA 4FP4A 3EGTA 4LUUA 5IMNA 4KK2A 2PS7A 2F89F 4NFJF 3AQ0A 3WCJA 3WEJA 3P8RA 3QKCA 4RYPA 3WCLA 2PS4A 3G4DA 3PKOA 3LGKA 3UCAA 5ILZA 3APZA 5B00A 1JFGA 4QXSF 5IM1A 3SDUA 3M01A 2OGDA 5B01A 4LXWA 3CKEA 1WMWA 4E9UA 1YHLA 5IVGA 4QPFA 4LFEA 4N9UA 1N20A 3G4FA 3VJCA 2P1CA 1N24A 4KVDA 2ONHA 3W7FA 5ILIA 4LZ0A 5E8KA 4F6VA 4UMJA 2Z7HA 2ZCOA 4RXDA 4E1EA 5HN7A 4LLTA 2F94F 3ZMCA 1HXGA 3KBKA 4KVWA 1RQIA 5AHUB 2Z78A 3P5RA 5IK9A 5ERMA 1V4HA 1YHKA 1N1BA 3ACYA
chains in the Genus database with same CATH topology
2E93A 3ICZA 2F8ZF 3RYWA 3S9VA 1HXAA 4Q23A 3WEFA 2E90A 5B0IA 5B03A 2E91A 5DGMF 3SDTA 4XQSF 5H9DA 3S4JA 3WCGA 3P8LA 3WSAA 2VF6A 3KB9A 1WKZA 5I1UA 2Z4XA 3MAVA 3NPRA 1PS1A 2E92A 3RBMA 2DH4A 3WCFA 4DWGA 5CG5A 5DJVF 2PS8A 5HN8A 3KRFA 4KQ5A 3LDWA 4LPGF 4EA1A 5JV1F 3WEHA 2Q80A 2ZEVA 3ZCDA 1WY0A 3CC9A 3NPKA 4MC8A 1DI1A 1WL0A 4NKFA 3EZ3A 1WL2A 5A0JA 5ILKA 3KRCA 1V4JA 2F7MF 3WCCA 4JZXA 4GA3A 5DZ2A 4KFAA 4F6XA 4KKMA 3LVSA 5B0KA 1UBYA 1JFAA 4H5CF 5IL3A 3OYRA 2Z52A 1UBVA 3LK5A 3N3LF 5B0JA 5B0MA 5IKAA 5IN8A 5HNAA 5B0LA 1HX9A 3VJ8A 4PVXF 2EWGA 3WE9A 2Q9YA 3KRFB 5KSXF 3EFQA 2Z4VA 4KPJA 3KROB 3DYHA 4LA6A 4ZQ8A 4JVJF 3ACWA 4GP2A 5E8LA 2Z4WA 5DJRF 3N46F 1YHMA 3IBAA 3ICKA 3WEGA 5DGSF 5JA0F 4RXCA 4DWBA 2O1OA 4RXEA 3RYEA 1YQ7A 2FORA 5IMPA 3WJOA 3NRIA 5DJPF 3N1WF 4MC3A 2E4OA 2FTZA 3B7LA 3LJIA 3AE0A 4DI5A 4JXNA 3ASXA 4GAXA 2AEKA 3DYGA 3TS7A 1WL1A 4LZ3A 1N1ZA 4N1ZF 2PS5A 3CP6A 1VG3A 5JV0F 4LTZA 3ZL6A 5HN9A 3LOMA 5ILDA 3ICMA 5AELA 4P0XA 3LZ9A 1ZW5A 3N49F 3P41A 1WL3A 2F92F 3M02A 3SDRA 1YYSA 3PYBA 2PS6A 4JZBA 1RQJA 4NG6A 4F62A 5IL8A 4LTVA 3Q1OA 3Q30A 3V1VA 5EAUA 3ICNA 1HM4A 5DIQF 4EA0A 1HXCA 3WCIA 3V66A 3WCDA 4DHDA 5JUZF 1N21A 3N6KF 1HM7A 2E95A 4H5EF 3ADZA 5IMIA 1DGPA 3AQCB 3KRPA 5DW7A 5EASA 2I19A 2OPNA 4LFGA 1V4KA 5EATA 3WCHA 4OMGA 4LOBA 3MZVA 4NUAA 3WCBA 2ZCQA 5ER8A 1VG2A 3Q2QA 1YYRA 4KUXA 1VG6A 4DXJA 3LEEA 5E8HA 5DGNF 4LA5A 5AFXA 3Q2ZA 2Z4YA 3N45F 1YV5A 3ACXA 2E94A 3LSNA 4NFIF 4KVIA 2Z7IA 1VG7A 2AZKA 2J1OA 2Z4ZA 2E8WA 4XQRF 3LLWA 3OABA 2RAHA 4H5DF 3RMGA 4LFVF 3KRAA 3WSBA 1V4IA 4P0WA 3WCMA 3WJKA 3N0FA 2ZCRA 3PYAA 4OMHA 4NKEA 4E9ZA 5ILJA 3M9UA 3P5PA 2Z50A 3KRPB 1YYQA 2E8UA 3OACA 1YYTA 3ZMBA 4DZWA 3VJDA 5IKHA 4HD1A 2ZCSA 3N5JF 2AETA 4XQTF 1KIYA 3KRCB 2AELA 5DHIA 5CG6A 2Q58A 4OKMA 3QQVA 2ZY1A 2ZEUA 4JXYA 4LZCA 1YYUA 4MC0A 3BNXA 3IPIA 3VJBA 3SDQA 5ILYA 4PVYF 2OPMA 2AZJA 2E8XA 4RNQA 1YJ4A 2E8TA 4OKZA 1RTRA 2J1PA 4GP1A 4EA2A 3OABB 3PDEA 3VJEA 3KRAB 5AYPA 3TFNA 4LPHF 1N23A 1VG4A 3VJ9A 3TC1A 1UBWA 2F8CF 5DHKA 3TFVA 3TFPA 3N3DA 3OACB 1V4EA 5A0KA 4KQSA 3SDVA 1N22A 4DEMF 5C05A 2H8OA 3V1XA 4NFKF 3DYFA 3WJNA 4FJQA 3WCAA 1FPSA 3WCEA 5ERNA 3M0GA 2J5CA 4LIXA 3N5HF 3WEIA 4OGUA 3LMDA 3BNYA 4RXAA 3ID0A 3M00A 4KPDA 4L2XF 4KVYA 1KIZA 5IK0A 2E8VA 3LGZB 5A0IA 3N1VF 3LG5A 3VJAA 4K10A 3SAEA 3KROA 3PH7A 2Q9ZA 2ONGA 4KWDA 4WK5A 2OA6A 5JV2F 3WC9A 5EROA 2F9KF 3WEKA 3ZOUA 5IK6A 3AQBB 4P0VA 2AZLA 3NF2A 1EZFA 4LLSA 4KQUA 5B02A 1UBXA 3N0GA 5ILHA 2QISA 4JYXA 4FP4A 3EGTA 4LUUA 5IMNA 4KK2A 2PS7A 2F89F 4NFJF 3AQ0A 3WCJA 3WEJA 3P8RA 3QKCA 4RYPA 3WCLA 2PS4A 3G4DA 3PKOA 3LGKA 3UCAA 5ILZA 3APZA 5B00A 1JFGA 4QXSF 5IM1A 3SDUA 3M01A 2OGDA 5B01A 4LXWA 3CKEA 1WMWA 4E9UA 1YHLA 5IVGA 4QPFA 4LFEA 4N9UA 1N20A 3G4FA 3VJCA 2P1CA 1N24A 4KVDA 2ONHA 3W7FA 5ILIA 4LZ0A 5E8KA 4F6VA 4UMJA 2Z7HA 2ZCOA 4RXDA 4E1EA 5HN7A 4LLTA 2F94F 3ZMCA 1HXGA 3KBKA 4KVWA 1RQIA 5AHUB 2Z78A 3P5RA 5IK9A 5ERMA 1V4HA 1YHKA 1N1BA 3ACYA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2E93 A;  3ICZ A;  2F8Z F;  3RYW A;  3S9V A;  1HXA A;  4Q23 A;  3WEF A;  2E90 A;  5B0I A;  5B03 A;  2E91 A;  5DGM F;  3SDT A;  4XQS F;  5H9D A;  3S4J A;  3WCG A;  3P8L A;  3WSA A;  2VF6 A;  3KB9 A;  1WKZ A;  5I1U A;  2Z4X A;  3MAV A;  3NPR A;  1PS1 A;  2E92 A;  3RBM A;  2DH4 A;  3WCF A;  4DWG A;  5CG5 A;  5DJV F;  2PS8 A;  5HN8 A;  3KRF A;  4KQ5 A;  3LDW A;  4LPG F;  4EA1 A;  5JV1 F;  3WEH A;  2Q80 A;  2ZEV A;  3ZCD A;  1WY0 A;  3CC9 A;  3NPK A;  4MC8 A;  1DI1 A;  1WL0 A;  4NKF A;  3EZ3 A;  1WL2 A;  5A0J A;  5ILK A;  3KRC A;  1V4J A;  2F7M F;  3WCC A;  4JZX A;  4GA3 A;  5DZ2 A;  4KFA A;  4F6X A;  4KKM A;  3LVS A;  5B0K A;  1UBY A;  1JFA A;  4H5C F;  5IL3 A;  3OYR A;  2Z52 A;  1UBV A;  3LK5 A;  3N3L F;  5B0J A;  5B0M A;  5IKA A;  5IN8 A;  5HNA A;  5B0L A;  1HX9 A;  3VJ8 A;  4PVX F;  2EWG A;  3WE9 A;  2Q9Y A;  3KRF B;  5KSX F;  3EFQ A;  2Z4V A;  4KPJ A;  3KRO B;  3DYH A;  4LA6 A;  4ZQ8 A;  4JVJ F;  3ACW A;  4GP2 A;  5E8L A;  2Z4W A;  5DJR F;  3N46 F;  1YHM A;  3IBA A;  3ICK A;  3WEG A;  5DGS F;  5JA0 F;  4RXC A;  4DWB A;  2O1O A;  4RXE A;  3RYE A;  1YQ7 A;  2FOR A;  5IMP A;  3WJO A;  3NRI A;  5DJP F;  3N1W F;  4MC3 A;  2E4O A;  2FTZ A;  3B7L A;  3LJI A;  3AE0 A;  4DI5 A;  4JXN A;  3ASX A;  4GAX A;  2AEK A;  3DYG A;  3TS7 A;  1WL1 A;  4LZ3 A;  1N1Z A;  4N1Z F;  2PS5 A;  3CP6 A;  1VG3 A;  5JV0 F;  4LTZ A;  3ZL6 A;  5HN9 A;  3LOM A;  5ILD A;  3ICM A;  5AEL A;  4P0X A;  3LZ9 A;  1ZW5 A;  3N49 F;  3P41 A;  1WL3 A;  2F92 F;  3M02 A;  3SDR A;  1YYS A;  3PYB A;  2PS6 A;  4JZB A;  1RQJ A;  4NG6 A;  4F62 A;  5IL8 A;  4LTV A;  3Q1O A;  3Q30 A;  3V1V A;  5EAU A;  3ICN A;  1HM4 A;  5DIQ F;  4EA0 A;  1HXC A;  3WCI A;  3V66 A;  3WCD A;  4DHD A;  5JUZ F;  1N21 A;  3N6K F;  1HM7 A;  2E95 A;  4H5E F;  3ADZ A;  5IMI A;  1DGP A;  3AQC B;  3KRP A;  5DW7 A;  5EAS A;  2I19 A;  2OPN A;  4LFG A;  1V4K A;  5EAT A;  3WCH A;  4OMG A;  4LOB A;  3MZV A;  4NUA A;  3WCB A;  2ZCQ A;  5ER8 A;  1VG2 A;  3Q2Q A;  1YYR A;  4KUX A;  1VG6 A;  4DXJ A;  3LEE A;  5E8H A;  5DGN F;  4LA5 A;  5AFX A;  3Q2Z A;  2Z4Y A;  3N45 F;  1YV5 A;  3ACX A;  2E94 A;  3LSN A;  4NFI F;  4KVI A;  2Z7I A;  1VG7 A;  2AZK A;  2J1O A;  2Z4Z A;  2E8W A;  4XQR F;  3LLW A;  3OAB A;  2RAH A;  4H5D F;  3RMG A;  4LFV F;  3KRA A;  3WSB A;  1V4I A;  4P0W A;  3WCM A;  3WJK A;  3N0F A;  2ZCR A;  3PYA A;  4OMH A;  4NKE A;  4E9Z A;  5ILJ A;  3M9U A;  3P5P A;  2Z50 A;  3KRP B;  1YYQ A;  2E8U A;  3OAC A;  1YYT A;  3ZMB A;  4DZW A;  3VJD A;  5IKH A;  4HD1 A;  2ZCS A;  3N5J F;  2AET A;  4XQT F;  1KIY A;  3KRC B;  2AEL A;  5DHI A;  5CG6 A;  2Q58 A;  4OKM A;  3QQV A;  2ZY1 A;  2ZEU A;  4JXY A;  4LZC A;  1YYU A;  4MC0 A;  3BNX A;  3IPI A;  3VJB A;  3SDQ A;  5ILY A;  4PVY F;  2OPM A;  2AZJ A;  2E8X A;  4RNQ A;  1YJ4 A;  2E8T A;  4OKZ A;  1RTR A;  2J1P A;  4GP1 A;  4EA2 A;  3OAB B;  3PDE A;  3VJE A;  3KRA B;  5AYP A;  3TFN A;  4LPH F;  1N23 A;  1VG4 A;  3VJ9 A;  3TC1 A;  1UBW A;  2F8C F;  5DHK A;  3TFV A;  3TFP A;  3N3D A;  3OAC B;  1V4E A;  5A0K A;  4KQS A;  3SDV A;  1N22 A;  4DEM F;  5C05 A;  2H8O A;  3V1X A;  4NFK F;  3DYF A;  3WJN A;  4FJQ A;  3WCA A;  1FPS A;  3WCE A;  5ERN A;  3M0G A;  2J5C A;  4LIX A;  3N5H F;  3WEI A;  4OGU A;  3LMD A;  3BNY A;  4RXA A;  3ID0 A;  3M00 A;  4KPD A;  4L2X F;  4KVY A;  1KIZ A;  5IK0 A;  2E8V A;  3LGZ B;  5A0I A;  3N1V F;  3LG5 A;  3VJA A;  4K10 A;  3SAE A;  3KRO A;  3PH7 A;  2Q9Z A;  2ONG A;  4KWD A;  4WK5 A;  2OA6 A;  5JV2 F;  3WC9 A;  5ERO A;  2F9K F;  3WEK A;  3ZOU A;  5IK6 A;  3AQB B;  4P0V A;  2AZL A;  3NF2 A;  1EZF A;  4LLS A;  4KQU A;  5B02 A;  1UBX A;  3N0G A;  5ILH A;  2QIS A;  4JYX A;  4FP4 A;  3EGT A;  4LUU A;  5IMN A;  4KK2 A;  2PS7 A;  2F89 F;  4NFJ F;  3AQ0 A;  3WCJ A;  3WEJ A;  3P8R A;  3QKC A;  4RYP A;  3WCL A;  2PS4 A;  3G4D A;  3PKO A;  3LGK A;  3UCA A;  5ILZ A;  3APZ A;  5B00 A;  1JFG A;  4QXS F;  5IM1 A;  3SDU A;  3M01 A;  2OGD A;  5B01 A;  4LXW A;  3CKE A;  1WMW A;  4E9U A;  1YHL A;  5IVG A;  4QPF A;  4LFE A;  4N9U A;  1N20 A;  3G4F A;  3VJC A;  2P1C A;  1N24 A;  4KVD A;  2ONH A;  3W7F A;  5ILI A;  4LZ0 A;  5E8K A;  4F6V A;  4UMJ A;  2Z7H A;  2ZCO A;  4RXD A;  4E1E A;  5HN7 A;  4LLT A;  2F94 F;  3ZMC A;  1HXG A;  3KBK A;  4KVW A;  1RQI A;  5AHU B;  2Z78 A;  3P5R A;  5IK9 A;  5ERM A;  1V4H A;  1YHK A;  1N1B A;  3ACY A; 
#chains in the Genus database with same CATH topology
 2E93 A;  3ICZ A;  2F8Z F;  3RYW A;  3S9V A;  1HXA A;  4Q23 A;  3WEF A;  2E90 A;  5B0I A;  5B03 A;  2E91 A;  5DGM F;  3SDT A;  4XQS F;  5H9D A;  3S4J A;  3WCG A;  3P8L A;  3WSA A;  2VF6 A;  3KB9 A;  1WKZ A;  5I1U A;  2Z4X A;  3MAV A;  3NPR A;  1PS1 A;  2E92 A;  3RBM A;  2DH4 A;  3WCF A;  4DWG A;  5CG5 A;  5DJV F;  2PS8 A;  5HN8 A;  3KRF A;  4KQ5 A;  3LDW A;  4LPG F;  4EA1 A;  5JV1 F;  3WEH A;  2Q80 A;  2ZEV A;  3ZCD A;  1WY0 A;  3CC9 A;  3NPK A;  4MC8 A;  1DI1 A;  1WL0 A;  4NKF A;  3EZ3 A;  1WL2 A;  5A0J A;  5ILK A;  3KRC A;  1V4J A;  2F7M F;  3WCC A;  4JZX A;  4GA3 A;  5DZ2 A;  4KFA A;  4F6X A;  4KKM A;  3LVS A;  5B0K A;  1UBY A;  1JFA A;  4H5C F;  5IL3 A;  3OYR A;  2Z52 A;  1UBV A;  3LK5 A;  3N3L F;  5B0J A;  5B0M A;  5IKA A;  5IN8 A;  5HNA A;  5B0L A;  1HX9 A;  3VJ8 A;  4PVX F;  2EWG A;  3WE9 A;  2Q9Y A;  3KRF B;  5KSX F;  3EFQ A;  2Z4V A;  4KPJ A;  3KRO B;  3DYH A;  4LA6 A;  4ZQ8 A;  4JVJ F;  3ACW A;  4GP2 A;  5E8L A;  2Z4W A;  5DJR F;  3N46 F;  1YHM A;  3IBA A;  3ICK A;  3WEG A;  5DGS F;  5JA0 F;  4RXC A;  4DWB A;  2O1O A;  4RXE A;  3RYE A;  1YQ7 A;  2FOR A;  5IMP A;  3WJO A;  3NRI A;  5DJP F;  3N1W F;  4MC3 A;  2E4O A;  2FTZ A;  3B7L A;  3LJI A;  3AE0 A;  4DI5 A;  4JXN A;  3ASX A;  4GAX A;  2AEK A;  3DYG A;  3TS7 A;  1WL1 A;  4LZ3 A;  1N1Z A;  4N1Z F;  2PS5 A;  3CP6 A;  1VG3 A;  5JV0 F;  4LTZ A;  3ZL6 A;  5HN9 A;  3LOM A;  5ILD A;  3ICM A;  5AEL A;  4P0X A;  3LZ9 A;  1ZW5 A;  3N49 F;  3P41 A;  1WL3 A;  2F92 F;  3M02 A;  3SDR A;  1YYS A;  3PYB A;  2PS6 A;  4JZB A;  1RQJ A;  4NG6 A;  4F62 A;  5IL8 A;  4LTV A;  3Q1O A;  3Q30 A;  3V1V A;  5EAU A;  3ICN A;  1HM4 A;  5DIQ F;  4EA0 A;  1HXC A;  3WCI A;  3V66 A;  3WCD A;  4DHD A;  5JUZ F;  1N21 A;  3N6K F;  1HM7 A;  2E95 A;  4H5E F;  3ADZ A;  5IMI A;  1DGP A;  3AQC B;  3KRP A;  5DW7 A;  5EAS A;  2I19 A;  2OPN A;  4LFG A;  1V4K A;  5EAT A;  3WCH A;  4OMG A;  4LOB A;  3MZV A;  4NUA A;  3WCB A;  2ZCQ A;  5ER8 A;  1VG2 A;  3Q2Q A;  1YYR A;  4KUX A;  1VG6 A;  4DXJ A;  3LEE A;  5E8H A;  5DGN F;  4LA5 A;  5AFX A;  3Q2Z A;  2Z4Y A;  3N45 F;  1YV5 A;  3ACX A;  2E94 A;  3LSN A;  4NFI F;  4KVI A;  2Z7I A;  1VG7 A;  2AZK A;  2J1O A;  2Z4Z A;  2E8W A;  4XQR F;  3LLW A;  3OAB A;  2RAH A;  4H5D F;  3RMG A;  4LFV F;  3KRA A;  3WSB A;  1V4I A;  4P0W A;  3WCM A;  3WJK A;  3N0F A;  2ZCR A;  3PYA A;  4OMH A;  4NKE A;  4E9Z A;  5ILJ A;  3M9U A;  3P5P A;  2Z50 A;  3KRP B;  1YYQ A;  2E8U A;  3OAC A;  1YYT A;  3ZMB A;  4DZW A;  3VJD A;  5IKH A;  4HD1 A;  2ZCS A;  3N5J F;  2AET A;  4XQT F;  1KIY A;  3KRC B;  2AEL A;  5DHI A;  5CG6 A;  2Q58 A;  4OKM A;  3QQV A;  2ZY1 A;  2ZEU A;  4JXY A;  4LZC A;  1YYU A;  4MC0 A;  3BNX A;  3IPI A;  3VJB A;  3SDQ A;  5ILY A;  4PVY F;  2OPM A;  2AZJ A;  2E8X A;  4RNQ A;  1YJ4 A;  2E8T A;  4OKZ A;  1RTR A;  2J1P A;  4GP1 A;  4EA2 A;  3OAB B;  3PDE A;  3VJE A;  3KRA B;  5AYP A;  3TFN A;  4LPH F;  1N23 A;  1VG4 A;  3VJ9 A;  3TC1 A;  1UBW A;  2F8C F;  5DHK A;  3TFV A;  3TFP A;  3N3D A;  3OAC B;  1V4E A;  5A0K A;  4KQS A;  3SDV A;  1N22 A;  4DEM F;  5C05 A;  2H8O A;  3V1X A;  4NFK F;  3DYF A;  3WJN A;  4FJQ A;  3WCA A;  1FPS A;  3WCE A;  5ERN A;  3M0G A;  2J5C A;  4LIX A;  3N5H F;  3WEI A;  4OGU A;  3LMD A;  3BNY A;  4RXA A;  3ID0 A;  3M00 A;  4KPD A;  4L2X F;  4KVY A;  1KIZ A;  5IK0 A;  2E8V A;  3LGZ B;  5A0I A;  3N1V F;  3LG5 A;  3VJA A;  4K10 A;  3SAE A;  3KRO A;  3PH7 A;  2Q9Z A;  2ONG A;  4KWD A;  4WK5 A;  2OA6 A;  5JV2 F;  3WC9 A;  5ERO A;  2F9K F;  3WEK A;  3ZOU A;  5IK6 A;  3AQB B;  4P0V A;  2AZL A;  3NF2 A;  1EZF A;  4LLS A;  4KQU A;  5B02 A;  1UBX A;  3N0G A;  5ILH A;  2QIS A;  4JYX A;  4FP4 A;  3EGT A;  4LUU A;  5IMN A;  4KK2 A;  2PS7 A;  2F89 F;  4NFJ F;  3AQ0 A;  3WCJ A;  3WEJ A;  3P8R A;  3QKC A;  4RYP A;  3WCL A;  2PS4 A;  3G4D A;  3PKO A;  3LGK A;  3UCA A;  5ILZ A;  3APZ A;  5B00 A;  1JFG A;  4QXS F;  5IM1 A;  3SDU A;  3M01 A;  2OGD A;  5B01 A;  4LXW A;  3CKE A;  1WMW A;  4E9U A;  1YHL A;  5IVG A;  4QPF A;  4LFE A;  4N9U A;  1N20 A;  3G4F A;  3VJC A;  2P1C A;  1N24 A;  4KVD A;  2ONH A;  3W7F A;  5ILI A;  4LZ0 A;  5E8K A;  4F6V A;  4UMJ A;  2Z7H A;  2ZCO A;  4RXD A;  4E1E A;  5HN7 A;  4LLT A;  2F94 F;  3ZMC A;  1HXG A;  3KBK A;  4KVW A;  1RQI A;  5AHU B;  2Z78 A;  3P5R A;  5IK9 A;  5ERM A;  1V4H A;  1YHK A;  1N1B A;  3ACY A; 
#chains in the Genus database with same CATH homology
 2E93 A;  3ICZ A;  2F8Z F;  3RYW A;  3S9V A;  1HXA A;  4Q23 A;  3WEF A;  2E90 A;  5B0I A;  5B03 A;  2E91 A;  5DGM F;  3SDT A;  4XQS F;  5H9D A;  3S4J A;  3WCG A;  3P8L A;  3WSA A;  2VF6 A;  3KB9 A;  1WKZ A;  5I1U A;  2Z4X A;  3MAV A;  3NPR A;  1PS1 A;  2E92 A;  3RBM A;  2DH4 A;  3WCF A;  4DWG A;  5CG5 A;  5DJV F;  2PS8 A;  5HN8 A;  3KRF A;  4KQ5 A;  3LDW A;  4LPG F;  4EA1 A;  5JV1 F;  3WEH A;  2Q80 A;  2ZEV A;  3ZCD A;  1WY0 A;  3CC9 A;  3NPK A;  4MC8 A;  1DI1 A;  1WL0 A;  4NKF A;  3EZ3 A;  1WL2 A;  5A0J A;  5ILK A;  3KRC A;  1V4J A;  2F7M F;  3WCC A;  4JZX A;  4GA3 A;  5DZ2 A;  4KFA A;  4F6X A;  4KKM A;  3LVS A;  5B0K A;  1UBY A;  1JFA A;  4H5C F;  5IL3 A;  3OYR A;  2Z52 A;  1UBV A;  3LK5 A;  3N3L F;  5B0J A;  5B0M A;  5IKA A;  5IN8 A;  5HNA A;  5B0L A;  1HX9 A;  3VJ8 A;  4PVX F;  2EWG A;  3WE9 A;  2Q9Y A;  3KRF B;  5KSX F;  3EFQ A;  2Z4V A;  4KPJ A;  3KRO B;  3DYH A;  4LA6 A;  4ZQ8 A;  4JVJ F;  3ACW A;  4GP2 A;  5E8L A;  2Z4W A;  5DJR F;  3N46 F;  1YHM A;  3IBA A;  3ICK A;  3WEG A;  5DGS F;  5JA0 F;  4RXC A;  4DWB A;  2O1O A;  4RXE A;  3RYE A;  1YQ7 A;  2FOR A;  5IMP A;  3WJO A;  3NRI A;  5DJP F;  3N1W F;  4MC3 A;  2E4O A;  2FTZ A;  3B7L A;  3LJI A;  3AE0 A;  4DI5 A;  4JXN A;  3ASX A;  4GAX A;  2AEK A;  3DYG A;  3TS7 A;  1WL1 A;  4LZ3 A;  1N1Z A;  4N1Z F;  2PS5 A;  3CP6 A;  1VG3 A;  5JV0 F;  4LTZ A;  3ZL6 A;  5HN9 A;  3LOM A;  5ILD A;  3ICM A;  5AEL A;  4P0X A;  3LZ9 A;  1ZW5 A;  3N49 F;  3P41 A;  1WL3 A;  2F92 F;  3M02 A;  3SDR A;  1YYS A;  3PYB A;  2PS6 A;  4JZB A;  1RQJ A;  4NG6 A;  4F62 A;  5IL8 A;  4LTV A;  3Q1O A;  3Q30 A;  3V1V A;  5EAU A;  3ICN A;  1HM4 A;  5DIQ F;  4EA0 A;  1HXC A;  3WCI A;  3V66 A;  3WCD A;  4DHD A;  5JUZ F;  1N21 A;  3N6K F;  1HM7 A;  2E95 A;  4H5E F;  3ADZ A;  5IMI A;  1DGP A;  3AQC B;  3KRP A;  5DW7 A;  5EAS A;  2I19 A;  2OPN A;  4LFG A;  1V4K A;  5EAT A;  3WCH A;  4OMG A;  4LOB A;  3MZV A;  4NUA A;  3WCB A;  2ZCQ A;  5ER8 A;  1VG2 A;  3Q2Q A;  1YYR A;  4KUX A;  1VG6 A;  4DXJ A;  3LEE A;  5E8H A;  5DGN F;  4LA5 A;  5AFX A;  3Q2Z A;  2Z4Y A;  3N45 F;  1YV5 A;  3ACX A;  2E94 A;  3LSN A;  4NFI F;  4KVI A;  2Z7I A;  1VG7 A;  2AZK A;  2J1O A;  2Z4Z A;  2E8W A;  4XQR F;  3LLW A;  3OAB A;  2RAH A;  4H5D F;  3RMG A;  4LFV F;  3KRA A;  3WSB A;  1V4I A;  4P0W A;  3WCM A;  3WJK A;  3N0F A;  2ZCR A;  3PYA A;  4OMH A;  4NKE A;  4E9Z A;  5ILJ A;  3M9U A;  3P5P A;  2Z50 A;  3KRP B;  1YYQ A;  2E8U A;  3OAC A;  1YYT A;  3ZMB A;  4DZW A;  3VJD A;  5IKH A;  4HD1 A;  2ZCS A;  3N5J F;  2AET A;  4XQT F;  1KIY A;  3KRC B;  2AEL A;  5DHI A;  5CG6 A;  2Q58 A;  4OKM A;  3QQV A;  2ZY1 A;  2ZEU A;  4JXY A;  4LZC A;  1YYU A;  4MC0 A;  3BNX A;  3IPI A;  3VJB A;  3SDQ A;  5ILY A;  4PVY F;  2OPM A;  2AZJ A;  2E8X A;  4RNQ A;  1YJ4 A;  2E8T A;  4OKZ A;  1RTR A;  2J1P A;  4GP1 A;  4EA2 A;  3OAB B;  3PDE A;  3VJE A;  3KRA B;  5AYP A;  3TFN A;  4LPH F;  1N23 A;  1VG4 A;  3VJ9 A;  3TC1 A;  1UBW A;  2F8C F;  5DHK A;  3TFV A;  3TFP A;  3N3D A;  3OAC B;  1V4E A;  5A0K A;  4KQS A;  3SDV A;  1N22 A;  4DEM F;  5C05 A;  2H8O A;  3V1X A;  4NFK F;  3DYF A;  3WJN A;  4FJQ A;  3WCA A;  1FPS A;  3WCE A;  5ERN A;  3M0G A;  2J5C A;  4LIX A;  3N5H F;  3WEI A;  4OGU A;  3LMD A;  3BNY A;  4RXA A;  3ID0 A;  3M00 A;  4KPD A;  4L2X F;  4KVY A;  1KIZ A;  5IK0 A;  2E8V A;  3LGZ B;  5A0I A;  3N1V F;  3LG5 A;  3VJA A;  4K10 A;  3SAE A;  3KRO A;  3PH7 A;  2Q9Z A;  2ONG A;  4KWD A;  4WK5 A;  2OA6 A;  5JV2 F;  3WC9 A;  5ERO A;  2F9K F;  3WEK A;  3ZOU A;  5IK6 A;  3AQB B;  4P0V A;  2AZL A;  3NF2 A;  1EZF A;  4LLS A;  4KQU A;  5B02 A;  1UBX A;  3N0G A;  5ILH A;  2QIS A;  4JYX A;  4FP4 A;  3EGT A;  4LUU A;  5IMN A;  4KK2 A;  2PS7 A;  2F89 F;  4NFJ F;  3AQ0 A;  3WCJ A;  3WEJ A;  3P8R A;  3QKC A;  4RYP A;  3WCL A;  2PS4 A;  3G4D A;  3PKO A;  3LGK A;  3UCA A;  5ILZ A;  3APZ A;  5B00 A;  1JFG A;  4QXS F;  5IM1 A;  3SDU A;  3M01 A;  2OGD A;  5B01 A;  4LXW A;  3CKE A;  1WMW A;  4E9U A;  1YHL A;  5IVG A;  4QPF A;  4LFE A;  4N9U A;  1N20 A;  3G4F A;  3VJC A;  2P1C A;  1N24 A;  4KVD A;  2ONH A;  3W7F A;  5ILI A;  4LZ0 A;  5E8K A;  4F6V A;  4UMJ A;  2Z7H A;  2ZCO A;  4RXD A;  4E1E A;  5HN7 A;  4LLT A;  2F94 F;  3ZMC A;  1HXG A;  3KBK A;  4KVW A;  1RQI A;  5AHU B;  2Z78 A;  3P5R A;  5IK9 A;  5ERM A;  1V4H A;  1YHK A;  1N1B A;  3ACY A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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