4RXEA

T. brucei farnesyl diphosphate synthase complexed with bisphosphonate bph-14
Total Genus 151
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
151
sequence length
367
structure length
358
Chain Sequence
MPMQMFMQVYDEIQMFLLEELELKFDMDPNRVRYLRKMMDTTCLGGKYNRGLTVIDVAESLLSLDGARRKRVLHDACVCGWMIEFLQAHYLVEDDIMDNSVTRRGKPCWYRHPDVTVQCAINDGLLLKSWTHMMAMHFFADRPFLQDLLCRFNRVDYTTAVGQLYDVTSMFDSNKLDPDVSQPTTTDFAEFTLSNYKRIVKYKTAYYTYLLPLVMGLIVSEALPTVDMGVTEELAMLMGEYFQVQDDVMDCFTPPERLGKVGTDIQDAKCSWLAVTFLAKASSAQVAEFKANYGSGDSEKVATVRRLYEEADLQGDYVAYEAAVAEQVKELIEKLRLCSPGFAASVETLWGKTYKRQK
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Farnesyl diphosphate synthase inhibitors with unique ligand-binding geometries.
pubmed doi rcsb
molecule tags Transferase/transferase inhibitor
source organism Trypanosoma brucei
molecule keywords Farnesyl pyrophosphate synthase
total genus 151
structure length 358
sequence length 367
chains with identical sequence B
ec nomenclature
pdb deposition date 2014-12-10

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00348 polyprenyl_synt Polyprenyl synthetase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.600.10 Mainly Alpha Orthogonal Bundle Farnesyl Diphosphate Synthase Farnesyl Diphosphate Synthase 4rxeA00
4P0WA 3ICKA 5EAUA 1YYSA 4JZBA 4JXYA 2E8TA 5ILJA 3WCDA 5JV0F 3WCAA 3VJDA 5IKAA 1VG6A 3LGZB 5IKHA 1HXGA 3N0GA 4OMHA 1JFAA 3WSBA 1YHKA 4NG6A 1YHMA 3N45F 3LEEA 2AZLA 5B03A 4WK5A 2Z50A 3VJ9A 4LIXA 1YYUA 4OKZA 2PS5A 3KB9A 5DJRF 3KROB 4DWBA 3P41A 5A0KA 3S9VA 5ILHA 1YYRA 2AETA 2RAHA 5AYPA 2AEKA 4LA5A 4LZ0A 2Z4WA 4H5EF 3DYFA 2O1OA 3S4JA 3ASXA 3G4DA 3Q2ZA 2E8XA 3VJEA 3WEJA 5JV2F 5A0JA 3WCMA 2Z78A 3W7FA 3LGKA 4NKFA 3RYWA 4E9ZA 2Q80A 3BNYA 3RYEA 3WCHA 3PDEA 1VG7A 3P5PA 3KRCB 4QPFA 1YQ7A 3VJAA 4JYXA 4LFVF 4KVWA 4OKMA 3WEKA 4DI5A 3EZ3A 3PYAA 3Q1OA 3M02A 4KK2A 4QXSF 5H9DA 3Q30A 3CP6A 3LJIA 4LTZA 5B0JA 5DJVF 3N3DA 5IN8A 2ZEVA 3WC9A 5HN9A 4JVJF 1N22A 3OABB 5ERNA 2ONHA 3LDWA 3ZL6A 4LUUA 1VG3A 3N5HF 5CG6A 1HM4A 2ZCQA 4OGUA 2F94F 2J1OA 4NFKF 3AQ0A 4XQRF 2J5CA 3PH7A 3WJOA 3UCAA 2Q58A 3P5RA 3LOMA 4F6VA 4RYPA 3V66A 1N1BA 3OACB 1KIYA 5E8HA 1V4HA 3KRAA 2E93A 3N46F 3V1VA 2E91A 5IMNA 1V4KA 4KQUA 2PS7A 5A0IA 3LVSA 3N49F 4DZWA 5ILYA 5JUZF 5DGNF 4H5CF 4RXEA 3KRFB 2AZKA 4GP2A 5IM1A 5HN8A 4KVYA 2AELA 3KRAB 3NPKA 2E8WA 1UBWA 3CC9A 1RQJA 2P1CA 2Q9YA 3WE9A 3OYRA 3SAEA 4EA1A 3G4FA 4KFAA 3ID0A 5B0KA 2F9KF 2VF6A 3ZMBA 2OPMA 1WKZA 3NPRA 3WCJA 3M0GA 2Z4VA 3SDRA 3AE0A 4E9UA 3DYGA 5B00A 4KVDA 4Q23A 5AHUB 3M9UA 4KPJA 1WL3A 5DHIA 4JXNA 3IPIA 3TS7A 5AFXA 3VJ8A 3WCBA 4PVXF 3DYHA 5EROA 1UBVA 4KWDA 5C05A 2Z4XA 4XQTF 3MAVA 4E1EA 3LMDA 3LG5A 4P0VA 2ZEUA 1WY0A 3N6KF 2E8VA 2PS6A 1WL0A 3SDTA 1DGPA 4K10A 3WJNA 3NF2A 4H5DF 4MC3A 3M00A 4DHDA 1RQIA 2Q9ZA 1UBYA 3N5JF 1HXCA 4GAXA 4LZCA 4LA6A 2ZCRA 3N1VF 4OMGA 3VJBA 1N21A 4UMJA 4LPHF 4LZ3A 2E8UA 3RBMA 4NFJF 1V4EA 1ZW5A 4GP1A 4DEMF 4F62A 5ILIA 3WCCA 4LTVA 5ILKA 3TFPA 4KQ5A 3LLWA 1N20A 3ICNA 1WL1A 1HX9A 1JFGA 1WMWA 3APZA 5EATA 5JA0F 3AQCB 5B0IA 5HN7A 3ACYA 3KRPA 3B7LA 4L2XF 3WCIA 3ZCDA 5IMPA 2PS4A 5IK6A 2ZCOA 5B0MA 1YJ4A 1YHLA 3WCEA 2F7MF 5E8LA 1YYQA 4KUXA 5ILZA 5AELA 2F89F 5DIQF 1KIZA 5EASA 1N1ZA 3ACXA 5DHKA 1VG4A 2QISA 4FJQA 5KSXF 2F8CF 5IK9A 3EGTA 3N3LF 4DXJA 3WEGA 2Z4YA 2Z7HA 4KKMA 3TFNA 5CG5A 3VJCA 4MC0A 4HD1A 4PVYF 5IK0A 3N0FA 4LFGA 1DI1A 4KQSA 3P8RA 3ACWA 4LLSA 3KROA 2FTZA 2J1PA 1V4JA 3ZMCA 4KVIA 1UBXA 3LK5A 4RNQA 4NKEA 4NUAA 4EA0A 2E94A 4LLTA 3TFVA 3KBKA 3AQBB 3N1WF 4RXCA 3NRIA 2PS8A 5B0LA 1RTRA 5IMIA 1YYTA 3WEIA 2OA6A 3WEFA 2F8ZF 1HM7A 4RXAA 2Z4ZA 3KRCA 5DGSF 2F92F 4JZXA 5ERMA 2E92A 3Q2QA 1HXAA 3EFQA 3RMGA 2AZJA 1VG2A 3WEHA 4LOBA 2E90A 4DWGA 5DW7A 4P0XA 3ICZA 1V4IA 3WCGA 3LSNA 2FORA 4NFIF 5IVGA 2H8OA 3BNXA 4F6XA 2ZY1A 3PYBA 3SDQA 2OPNA 5JV1F 2I19A 4LPGF 5DZ2A 3LZ9A 3OABA 1N23A 4KPDA 5DGMF 3ADZA 3CKEA 5ILDA 5IL3A 4XQSF 4ZQ8A 2EWGA 4LXWA 3TC1A 4N9UA 3SDUA 3WCLA 4FP4A 1EZFA 1WL2A 5I1UA 5B01A 4RXDA 3P8LA 2E4OA 3OACA 4GA3A 5ER8A 5IL8A 3SDVA 2Z52A 5HNAA 3PKOA 2Z7IA 2DH4A 2E95A 3M01A 2ZCSA 3WCFA 3QQVA 1FPSA 3WJKA 2OGDA 3QKCA 2ONGA 4MC8A 3WSAA 5B02A 1YV5A 3IBAA 3KRPB 3V1XA 4N1ZF 3ZOUA 1PS1A 5E8KA 3ICMA 3MZVA 1N24A 4LFEA 4EA2A 5DJPF 3KRFA
chains in the Genus database with same CATH superfamily
4P0WA 3ICKA 5EAUA 1YYSA 4JZBA 4JXYA 2E8TA 5ILJA 3WCDA 5JV0F 3WCAA 3VJDA 5IKAA 1VG6A 3LGZB 5IKHA 1HXGA 3N0GA 4OMHA 1JFAA 3WSBA 1YHKA 4NG6A 1YHMA 3N45F 3LEEA 2AZLA 5B03A 4WK5A 2Z50A 3VJ9A 4LIXA 1YYUA 4OKZA 2PS5A 3KB9A 5DJRF 3KROB 4DWBA 3P41A 5A0KA 3S9VA 5ILHA 1YYRA 2AETA 2RAHA 5AYPA 2AEKA 4LA5A 4LZ0A 2Z4WA 4H5EF 3DYFA 2O1OA 3S4JA 3ASXA 3G4DA 3Q2ZA 2E8XA 3VJEA 3WEJA 5JV2F 5A0JA 3WCMA 2Z78A 3W7FA 3LGKA 4NKFA 3RYWA 4E9ZA 2Q80A 3BNYA 3RYEA 3WCHA 3PDEA 1VG7A 3P5PA 3KRCB 4QPFA 1YQ7A 3VJAA 4JYXA 4LFVF 4KVWA 4OKMA 3WEKA 4DI5A 3EZ3A 3PYAA 3Q1OA 3M02A 4KK2A 4QXSF 5H9DA 3Q30A 3CP6A 3LJIA 4LTZA 5B0JA 5DJVF 3N3DA 5IN8A 2ZEVA 3WC9A 5HN9A 4JVJF 1N22A 3OABB 5ERNA 2ONHA 3LDWA 3ZL6A 4LUUA 1VG3A 3N5HF 5CG6A 1HM4A 2ZCQA 4OGUA 2F94F 2J1OA 4NFKF 3AQ0A 4XQRF 2J5CA 3PH7A 3WJOA 3UCAA 2Q58A 3P5RA 3LOMA 4F6VA 4RYPA 3V66A 1N1BA 3OACB 1KIYA 5E8HA 1V4HA 3KRAA 2E93A 3N46F 3V1VA 2E91A 5IMNA 1V4KA 4KQUA 2PS7A 5A0IA 3LVSA 3N49F 4DZWA 5ILYA 5JUZF 5DGNF 4H5CF 4RXEA 3KRFB 2AZKA 4GP2A 5IM1A 5HN8A 4KVYA 2AELA 3KRAB 3NPKA 2E8WA 1UBWA 3CC9A 1RQJA 2P1CA 2Q9YA 3WE9A 3OYRA 3SAEA 4EA1A 3G4FA 4KFAA 3ID0A 5B0KA 2F9KF 2VF6A 3ZMBA 2OPMA 1WKZA 3NPRA 3WCJA 3M0GA 2Z4VA 3SDRA 3AE0A 4E9UA 3DYGA 5B00A 4KVDA 4Q23A 5AHUB 3M9UA 4KPJA 1WL3A 5DHIA 4JXNA 3IPIA 3TS7A 5AFXA 3VJ8A 3WCBA 4PVXF 3DYHA 5EROA 1UBVA 4KWDA 5C05A 2Z4XA 4XQTF 3MAVA 4E1EA 3LMDA 3LG5A 4P0VA 2ZEUA 1WY0A 3N6KF 2E8VA 2PS6A 1WL0A 3SDTA 1DGPA 4K10A 3WJNA 3NF2A 4H5DF 4MC3A 3M00A 4DHDA 1RQIA 2Q9ZA 1UBYA 3N5JF 1HXCA 4GAXA 4LZCA 4LA6A 2ZCRA 3N1VF 4OMGA 3VJBA 1N21A 4UMJA 4LPHF 4LZ3A 2E8UA 3RBMA 4NFJF 1V4EA 1ZW5A 4GP1A 4DEMF 4F62A 5ILIA 3WCCA 4LTVA 5ILKA 3TFPA 4KQ5A 3LLWA 1N20A 3ICNA 1WL1A 1HX9A 1JFGA 1WMWA 3APZA 5EATA 5JA0F 3AQCB 5B0IA 5HN7A 3ACYA 3KRPA 3B7LA 4L2XF 3WCIA 3ZCDA 5IMPA 2PS4A 5IK6A 2ZCOA 5B0MA 1YJ4A 1YHLA 3WCEA 2F7MF 5E8LA 1YYQA 4KUXA 5ILZA 5AELA 2F89F 5DIQF 1KIZA 5EASA 1N1ZA 3ACXA 5DHKA 1VG4A 2QISA 4FJQA 5KSXF 2F8CF 5IK9A 3EGTA 3N3LF 4DXJA 3WEGA 2Z4YA 2Z7HA 4KKMA 3TFNA 5CG5A 3VJCA 4MC0A 4HD1A 4PVYF 5IK0A 3N0FA 4LFGA 1DI1A 4KQSA 3P8RA 3ACWA 4LLSA 3KROA 2FTZA 2J1PA 1V4JA 3ZMCA 4KVIA 1UBXA 3LK5A 4RNQA 4NKEA 4NUAA 4EA0A 2E94A 4LLTA 3TFVA 3KBKA 3AQBB 3N1WF 4RXCA 3NRIA 2PS8A 5B0LA 1RTRA 5IMIA 1YYTA 3WEIA 2OA6A 3WEFA 2F8ZF 1HM7A 4RXAA 2Z4ZA 3KRCA 5DGSF 2F92F 4JZXA 5ERMA 2E92A 3Q2QA 1HXAA 3EFQA 3RMGA 2AZJA 1VG2A 3WEHA 4LOBA 2E90A 4DWGA 5DW7A 4P0XA 3ICZA 1V4IA 3WCGA 3LSNA 2FORA 4NFIF 5IVGA 2H8OA 3BNXA 4F6XA 2ZY1A 3PYBA 3SDQA 2OPNA 5JV1F 2I19A 4LPGF 5DZ2A 3LZ9A 3OABA 1N23A 4KPDA 5DGMF 3ADZA 3CKEA 5ILDA 5IL3A 4XQSF 4ZQ8A 2EWGA 4LXWA 3TC1A 4N9UA 3SDUA 3WCLA 4FP4A 1EZFA 1WL2A 5I1UA 5B01A 4RXDA 3P8LA 2E4OA 3OACA 4GA3A 5ER8A 5IL8A 3SDVA 2Z52A 5HNAA 3PKOA 2Z7IA 2DH4A 2E95A 3M01A 2ZCSA 3WCFA 3QQVA 1FPSA 3WJKA 2OGDA 3QKCA 2ONGA 4MC8A 3WSAA 5B02A 1YV5A 3IBAA 3KRPB 3V1XA 4N1ZF 3ZOUA 1PS1A 5E8KA 3ICMA 3MZVA 1N24A 4LFEA 4EA2A 5DJPF 3KRFA
chains in the Genus database with same CATH topology
4P0WA 3ICKA 5EAUA 1YYSA 4JZBA 4JXYA 2E8TA 5ILJA 3WCDA 5JV0F 3WCAA 3VJDA 5IKAA 1VG6A 3LGZB 5IKHA 1HXGA 3N0GA 4OMHA 1JFAA 3WSBA 1YHKA 4NG6A 1YHMA 3N45F 3LEEA 2AZLA 5B03A 4WK5A 2Z50A 3VJ9A 4LIXA 1YYUA 4OKZA 2PS5A 3KB9A 5DJRF 3KROB 4DWBA 3P41A 5A0KA 3S9VA 5ILHA 1YYRA 2AETA 2RAHA 5AYPA 2AEKA 4LA5A 4LZ0A 2Z4WA 4H5EF 3DYFA 2O1OA 3S4JA 3ASXA 3G4DA 3Q2ZA 2E8XA 3VJEA 3WEJA 5JV2F 5A0JA 3WCMA 2Z78A 3W7FA 3LGKA 4NKFA 3RYWA 4E9ZA 2Q80A 3BNYA 3RYEA 3WCHA 3PDEA 1VG7A 3P5PA 3KRCB 4QPFA 1YQ7A 3VJAA 4JYXA 4LFVF 4KVWA 4OKMA 3WEKA 4DI5A 3EZ3A 3PYAA 3Q1OA 3M02A 4KK2A 4QXSF 5H9DA 3Q30A 3CP6A 3LJIA 4LTZA 5B0JA 5DJVF 3N3DA 5IN8A 2ZEVA 3WC9A 5HN9A 4JVJF 1N22A 3OABB 5ERNA 2ONHA 3LDWA 3ZL6A 4LUUA 1VG3A 3N5HF 5CG6A 1HM4A 2ZCQA 4OGUA 2F94F 2J1OA 4NFKF 3AQ0A 4XQRF 2J5CA 3PH7A 3WJOA 3UCAA 2Q58A 3P5RA 3LOMA 4F6VA 4RYPA 3V66A 1N1BA 3OACB 1KIYA 5E8HA 1V4HA 3KRAA 2E93A 3N46F 3V1VA 2E91A 5IMNA 1V4KA 4KQUA 2PS7A 5A0IA 3LVSA 3N49F 4DZWA 5ILYA 5JUZF 5DGNF 4H5CF 4RXEA 3KRFB 2AZKA 4GP2A 5IM1A 5HN8A 4KVYA 2AELA 3KRAB 3NPKA 2E8WA 1UBWA 3CC9A 1RQJA 2P1CA 2Q9YA 3WE9A 3OYRA 3SAEA 4EA1A 3G4FA 4KFAA 3ID0A 5B0KA 2F9KF 2VF6A 3ZMBA 2OPMA 1WKZA 3NPRA 3WCJA 3M0GA 2Z4VA 3SDRA 3AE0A 4E9UA 3DYGA 5B00A 4KVDA 4Q23A 5AHUB 3M9UA 4KPJA 1WL3A 5DHIA 4JXNA 3IPIA 3TS7A 5AFXA 3VJ8A 3WCBA 4PVXF 3DYHA 5EROA 1UBVA 4KWDA 5C05A 2Z4XA 4XQTF 3MAVA 4E1EA 3LMDA 3LG5A 4P0VA 2ZEUA 1WY0A 3N6KF 2E8VA 2PS6A 1WL0A 3SDTA 1DGPA 4K10A 3WJNA 3NF2A 4H5DF 4MC3A 3M00A 4DHDA 1RQIA 2Q9ZA 1UBYA 3N5JF 1HXCA 4GAXA 4LZCA 4LA6A 2ZCRA 3N1VF 4OMGA 3VJBA 1N21A 4UMJA 4LPHF 4LZ3A 2E8UA 3RBMA 4NFJF 1V4EA 1ZW5A 4GP1A 4DEMF 4F62A 5ILIA 3WCCA 4LTVA 5ILKA 3TFPA 4KQ5A 3LLWA 1N20A 3ICNA 1WL1A 1HX9A 1JFGA 1WMWA 3APZA 5EATA 5JA0F 3AQCB 5B0IA 5HN7A 3ACYA 3KRPA 3B7LA 4L2XF 3WCIA 3ZCDA 5IMPA 2PS4A 5IK6A 2ZCOA 5B0MA 1YJ4A 1YHLA 3WCEA 2F7MF 5E8LA 1YYQA 4KUXA 5ILZA 5AELA 2F89F 5DIQF 1KIZA 5EASA 1N1ZA 3ACXA 5DHKA 1VG4A 2QISA 4FJQA 5KSXF 2F8CF 5IK9A 3EGTA 3N3LF 4DXJA 3WEGA 2Z4YA 2Z7HA 4KKMA 3TFNA 5CG5A 3VJCA 4MC0A 4HD1A 4PVYF 5IK0A 3N0FA 4LFGA 1DI1A 4KQSA 3P8RA 3ACWA 4LLSA 3KROA 2FTZA 2J1PA 1V4JA 3ZMCA 4KVIA 1UBXA 3LK5A 4RNQA 4NKEA 4NUAA 4EA0A 2E94A 4LLTA 3TFVA 3KBKA 3AQBB 3N1WF 4RXCA 3NRIA 2PS8A 5B0LA 1RTRA 5IMIA 1YYTA 3WEIA 2OA6A 3WEFA 2F8ZF 1HM7A 4RXAA 2Z4ZA 3KRCA 5DGSF 2F92F 4JZXA 5ERMA 2E92A 3Q2QA 1HXAA 3EFQA 3RMGA 2AZJA 1VG2A 3WEHA 4LOBA 2E90A 4DWGA 5DW7A 4P0XA 3ICZA 1V4IA 3WCGA 3LSNA 2FORA 4NFIF 5IVGA 2H8OA 3BNXA 4F6XA 2ZY1A 3PYBA 3SDQA 2OPNA 5JV1F 2I19A 4LPGF 5DZ2A 3LZ9A 3OABA 1N23A 4KPDA 5DGMF 3ADZA 3CKEA 5ILDA 5IL3A 4XQSF 4ZQ8A 2EWGA 4LXWA 3TC1A 4N9UA 3SDUA 3WCLA 4FP4A 1EZFA 1WL2A 5I1UA 5B01A 4RXDA 3P8LA 2E4OA 3OACA 4GA3A 5ER8A 5IL8A 3SDVA 2Z52A 5HNAA 3PKOA 2Z7IA 2DH4A 2E95A 3M01A 2ZCSA 3WCFA 3QQVA 1FPSA 3WJKA 2OGDA 3QKCA 2ONGA 4MC8A 3WSAA 5B02A 1YV5A 3IBAA 3KRPB 3V1XA 4N1ZF 3ZOUA 1PS1A 5E8KA 3ICMA 3MZVA 1N24A 4LFEA 4EA2A 5DJPF 3KRFA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4P0W A;  3ICK A;  5EAU A;  1YYS A;  4JZB A;  4JXY A;  2E8T A;  5ILJ A;  3WCD A;  5JV0 F;  3WCA A;  3VJD A;  5IKA A;  1VG6 A;  3LGZ B;  5IKH A;  1HXG A;  3N0G A;  4OMH A;  1JFA A;  3WSB A;  1YHK A;  4NG6 A;  1YHM A;  3N45 F;  3LEE A;  2AZL A;  5B03 A;  4WK5 A;  2Z50 A;  3VJ9 A;  4LIX A;  1YYU A;  4OKZ A;  2PS5 A;  3KB9 A;  5DJR F;  3KRO B;  4DWB A;  3P41 A;  5A0K A;  3S9V A;  5ILH A;  1YYR A;  2AET A;  2RAH A;  5AYP A;  2AEK A;  4LA5 A;  4LZ0 A;  2Z4W A;  4H5E F;  3DYF A;  2O1O A;  3S4J A;  3ASX A;  3G4D A;  3Q2Z A;  2E8X A;  3VJE A;  3WEJ A;  5JV2 F;  5A0J A;  3WCM A;  2Z78 A;  3W7F A;  3LGK A;  4NKF A;  3RYW A;  4E9Z A;  2Q80 A;  3BNY A;  3RYE A;  3WCH A;  3PDE A;  1VG7 A;  3P5P A;  3KRC B;  4QPF A;  1YQ7 A;  3VJA A;  4JYX A;  4LFV F;  4KVW A;  4OKM A;  3WEK A;  4DI5 A;  3EZ3 A;  3PYA A;  3Q1O A;  3M02 A;  4KK2 A;  4QXS F;  5H9D A;  3Q30 A;  3CP6 A;  3LJI A;  4LTZ A;  5B0J A;  5DJV F;  3N3D A;  5IN8 A;  2ZEV A;  3WC9 A;  5HN9 A;  4JVJ F;  1N22 A;  3OAB B;  5ERN A;  2ONH A;  3LDW A;  3ZL6 A;  4LUU A;  1VG3 A;  3N5H F;  5CG6 A;  1HM4 A;  2ZCQ A;  4OGU A;  2F94 F;  2J1O A;  4NFK F;  3AQ0 A;  4XQR F;  2J5C A;  3PH7 A;  3WJO A;  3UCA A;  2Q58 A;  3P5R A;  3LOM A;  4F6V A;  4RYP A;  3V66 A;  1N1B A;  3OAC B;  1KIY A;  5E8H A;  1V4H A;  3KRA A;  2E93 A;  3N46 F;  3V1V A;  2E91 A;  5IMN A;  1V4K A;  4KQU A;  2PS7 A;  5A0I A;  3LVS A;  3N49 F;  4DZW A;  5ILY A;  5JUZ F;  5DGN F;  4H5C F;  4RXE A;  3KRF B;  2AZK A;  4GP2 A;  5IM1 A;  5HN8 A;  4KVY A;  2AEL A;  3KRA B;  3NPK A;  2E8W A;  1UBW A;  3CC9 A;  1RQJ A;  2P1C A;  2Q9Y A;  3WE9 A;  3OYR A;  3SAE A;  4EA1 A;  3G4F A;  4KFA A;  3ID0 A;  5B0K A;  2F9K F;  2VF6 A;  3ZMB A;  2OPM A;  1WKZ A;  3NPR A;  3WCJ A;  3M0G A;  2Z4V A;  3SDR A;  3AE0 A;  4E9U A;  3DYG A;  5B00 A;  4KVD A;  4Q23 A;  5AHU B;  3M9U A;  4KPJ A;  1WL3 A;  5DHI A;  4JXN A;  3IPI A;  3TS7 A;  5AFX A;  3VJ8 A;  3WCB A;  4PVX F;  3DYH A;  5ERO A;  1UBV A;  4KWD A;  5C05 A;  2Z4X A;  4XQT F;  3MAV A;  4E1E A;  3LMD A;  3LG5 A;  4P0V A;  2ZEU A;  1WY0 A;  3N6K F;  2E8V A;  2PS6 A;  1WL0 A;  3SDT A;  1DGP A;  4K10 A;  3WJN A;  3NF2 A;  4H5D F;  4MC3 A;  3M00 A;  4DHD A;  1RQI A;  2Q9Z A;  1UBY A;  3N5J F;  1HXC A;  4GAX A;  4LZC A;  4LA6 A;  2ZCR A;  3N1V F;  4OMG A;  3VJB A;  1N21 A;  4UMJ A;  4LPH F;  4LZ3 A;  2E8U A;  3RBM A;  4NFJ F;  1V4E A;  1ZW5 A;  4GP1 A;  4DEM F;  4F62 A;  5ILI A;  3WCC A;  4LTV A;  5ILK A;  3TFP A;  4KQ5 A;  3LLW A;  1N20 A;  3ICN A;  1WL1 A;  1HX9 A;  1JFG A;  1WMW A;  3APZ A;  5EAT A;  5JA0 F;  3AQC B;  5B0I A;  5HN7 A;  3ACY A;  3KRP A;  3B7L A;  4L2X F;  3WCI A;  3ZCD A;  5IMP A;  2PS4 A;  5IK6 A;  2ZCO A;  5B0M A;  1YJ4 A;  1YHL A;  3WCE A;  2F7M F;  5E8L A;  1YYQ A;  4KUX A;  5ILZ A;  5AEL A;  2F89 F;  5DIQ F;  1KIZ A;  5EAS A;  1N1Z A;  3ACX A;  5DHK A;  1VG4 A;  2QIS A;  4FJQ A;  5KSX F;  2F8C F;  5IK9 A;  3EGT A;  3N3L F;  4DXJ A;  3WEG A;  2Z4Y A;  2Z7H A;  4KKM A;  3TFN A;  5CG5 A;  3VJC A;  4MC0 A;  4HD1 A;  4PVY F;  5IK0 A;  3N0F A;  4LFG A;  1DI1 A;  4KQS A;  3P8R A;  3ACW A;  4LLS A;  3KRO A;  2FTZ A;  2J1P A;  1V4J A;  3ZMC A;  4KVI A;  1UBX A;  3LK5 A;  4RNQ A;  4NKE A;  4NUA A;  4EA0 A;  2E94 A;  4LLT A;  3TFV A;  3KBK A;  3AQB B;  3N1W F;  4RXC A;  3NRI A;  2PS8 A;  5B0L A;  1RTR A;  5IMI A;  1YYT A;  3WEI A;  2OA6 A;  3WEF A;  2F8Z F;  1HM7 A;  4RXA A;  2Z4Z A;  3KRC A;  5DGS F;  2F92 F;  4JZX A;  5ERM A;  2E92 A;  3Q2Q A;  1HXA A;  3EFQ A;  3RMG A;  2AZJ A;  1VG2 A;  3WEH A;  4LOB A;  2E90 A;  4DWG A;  5DW7 A;  4P0X A;  3ICZ A;  1V4I A;  3WCG A;  3LSN A;  2FOR A;  4NFI F;  5IVG A;  2H8O A;  3BNX A;  4F6X A;  2ZY1 A;  3PYB A;  3SDQ A;  2OPN A;  5JV1 F;  2I19 A;  4LPG F;  5DZ2 A;  3LZ9 A;  3OAB A;  1N23 A;  4KPD A;  5DGM F;  3ADZ A;  3CKE A;  5ILD A;  5IL3 A;  4XQS F;  4ZQ8 A;  2EWG A;  4LXW A;  3TC1 A;  4N9U A;  3SDU A;  3WCL A;  4FP4 A;  1EZF A;  1WL2 A;  5I1U A;  5B01 A;  4RXD A;  3P8L A;  2E4O A;  3OAC A;  4GA3 A;  5ER8 A;  5IL8 A;  3SDV A;  2Z52 A;  5HNA A;  3PKO A;  2Z7I A;  2DH4 A;  2E95 A;  3M01 A;  2ZCS A;  3WCF A;  3QQV A;  1FPS A;  3WJK A;  2OGD A;  3QKC A;  2ONG A;  4MC8 A;  3WSA A;  5B02 A;  1YV5 A;  3IBA A;  3KRP B;  3V1X A;  4N1Z F;  3ZOU A;  1PS1 A;  5E8K A;  3ICM A;  3MZV A;  1N24 A;  4LFE A;  4EA2 A;  5DJP F;  3KRF A; 
#chains in the Genus database with same CATH topology
 4P0W A;  3ICK A;  5EAU A;  1YYS A;  4JZB A;  4JXY A;  2E8T A;  5ILJ A;  3WCD A;  5JV0 F;  3WCA A;  3VJD A;  5IKA A;  1VG6 A;  3LGZ B;  5IKH A;  1HXG A;  3N0G A;  4OMH A;  1JFA A;  3WSB A;  1YHK A;  4NG6 A;  1YHM A;  3N45 F;  3LEE A;  2AZL A;  5B03 A;  4WK5 A;  2Z50 A;  3VJ9 A;  4LIX A;  1YYU A;  4OKZ A;  2PS5 A;  3KB9 A;  5DJR F;  3KRO B;  4DWB A;  3P41 A;  5A0K A;  3S9V A;  5ILH A;  1YYR A;  2AET A;  2RAH A;  5AYP A;  2AEK A;  4LA5 A;  4LZ0 A;  2Z4W A;  4H5E F;  3DYF A;  2O1O A;  3S4J A;  3ASX A;  3G4D A;  3Q2Z A;  2E8X A;  3VJE A;  3WEJ A;  5JV2 F;  5A0J A;  3WCM A;  2Z78 A;  3W7F A;  3LGK A;  4NKF A;  3RYW A;  4E9Z A;  2Q80 A;  3BNY A;  3RYE A;  3WCH A;  3PDE A;  1VG7 A;  3P5P A;  3KRC B;  4QPF A;  1YQ7 A;  3VJA A;  4JYX A;  4LFV F;  4KVW A;  4OKM A;  3WEK A;  4DI5 A;  3EZ3 A;  3PYA A;  3Q1O A;  3M02 A;  4KK2 A;  4QXS F;  5H9D A;  3Q30 A;  3CP6 A;  3LJI A;  4LTZ A;  5B0J A;  5DJV F;  3N3D A;  5IN8 A;  2ZEV A;  3WC9 A;  5HN9 A;  4JVJ F;  1N22 A;  3OAB B;  5ERN A;  2ONH A;  3LDW A;  3ZL6 A;  4LUU A;  1VG3 A;  3N5H F;  5CG6 A;  1HM4 A;  2ZCQ A;  4OGU A;  2F94 F;  2J1O A;  4NFK F;  3AQ0 A;  4XQR F;  2J5C A;  3PH7 A;  3WJO A;  3UCA A;  2Q58 A;  3P5R A;  3LOM A;  4F6V A;  4RYP A;  3V66 A;  1N1B A;  3OAC B;  1KIY A;  5E8H A;  1V4H A;  3KRA A;  2E93 A;  3N46 F;  3V1V A;  2E91 A;  5IMN A;  1V4K A;  4KQU A;  2PS7 A;  5A0I A;  3LVS A;  3N49 F;  4DZW A;  5ILY A;  5JUZ F;  5DGN F;  4H5C F;  4RXE A;  3KRF B;  2AZK A;  4GP2 A;  5IM1 A;  5HN8 A;  4KVY A;  2AEL A;  3KRA B;  3NPK A;  2E8W A;  1UBW A;  3CC9 A;  1RQJ A;  2P1C A;  2Q9Y A;  3WE9 A;  3OYR A;  3SAE A;  4EA1 A;  3G4F A;  4KFA A;  3ID0 A;  5B0K A;  2F9K F;  2VF6 A;  3ZMB A;  2OPM A;  1WKZ A;  3NPR A;  3WCJ A;  3M0G A;  2Z4V A;  3SDR A;  3AE0 A;  4E9U A;  3DYG A;  5B00 A;  4KVD A;  4Q23 A;  5AHU B;  3M9U A;  4KPJ A;  1WL3 A;  5DHI A;  4JXN A;  3IPI A;  3TS7 A;  5AFX A;  3VJ8 A;  3WCB A;  4PVX F;  3DYH A;  5ERO A;  1UBV A;  4KWD A;  5C05 A;  2Z4X A;  4XQT F;  3MAV A;  4E1E A;  3LMD A;  3LG5 A;  4P0V A;  2ZEU A;  1WY0 A;  3N6K F;  2E8V A;  2PS6 A;  1WL0 A;  3SDT A;  1DGP A;  4K10 A;  3WJN A;  3NF2 A;  4H5D F;  4MC3 A;  3M00 A;  4DHD A;  1RQI A;  2Q9Z A;  1UBY A;  3N5J F;  1HXC A;  4GAX A;  4LZC A;  4LA6 A;  2ZCR A;  3N1V F;  4OMG A;  3VJB A;  1N21 A;  4UMJ A;  4LPH F;  4LZ3 A;  2E8U A;  3RBM A;  4NFJ F;  1V4E A;  1ZW5 A;  4GP1 A;  4DEM F;  4F62 A;  5ILI A;  3WCC A;  4LTV A;  5ILK A;  3TFP A;  4KQ5 A;  3LLW A;  1N20 A;  3ICN A;  1WL1 A;  1HX9 A;  1JFG A;  1WMW A;  3APZ A;  5EAT A;  5JA0 F;  3AQC B;  5B0I A;  5HN7 A;  3ACY A;  3KRP A;  3B7L A;  4L2X F;  3WCI A;  3ZCD A;  5IMP A;  2PS4 A;  5IK6 A;  2ZCO A;  5B0M A;  1YJ4 A;  1YHL A;  3WCE A;  2F7M F;  5E8L A;  1YYQ A;  4KUX A;  5ILZ A;  5AEL A;  2F89 F;  5DIQ F;  1KIZ A;  5EAS A;  1N1Z A;  3ACX A;  5DHK A;  1VG4 A;  2QIS A;  4FJQ A;  5KSX F;  2F8C F;  5IK9 A;  3EGT A;  3N3L F;  4DXJ A;  3WEG A;  2Z4Y A;  2Z7H A;  4KKM A;  3TFN A;  5CG5 A;  3VJC A;  4MC0 A;  4HD1 A;  4PVY F;  5IK0 A;  3N0F A;  4LFG A;  1DI1 A;  4KQS A;  3P8R A;  3ACW A;  4LLS A;  3KRO A;  2FTZ A;  2J1P A;  1V4J A;  3ZMC A;  4KVI A;  1UBX A;  3LK5 A;  4RNQ A;  4NKE A;  4NUA A;  4EA0 A;  2E94 A;  4LLT A;  3TFV A;  3KBK A;  3AQB B;  3N1W F;  4RXC A;  3NRI A;  2PS8 A;  5B0L A;  1RTR A;  5IMI A;  1YYT A;  3WEI A;  2OA6 A;  3WEF A;  2F8Z F;  1HM7 A;  4RXA A;  2Z4Z A;  3KRC A;  5DGS F;  2F92 F;  4JZX A;  5ERM A;  2E92 A;  3Q2Q A;  1HXA A;  3EFQ A;  3RMG A;  2AZJ A;  1VG2 A;  3WEH A;  4LOB A;  2E90 A;  4DWG A;  5DW7 A;  4P0X A;  3ICZ A;  1V4I A;  3WCG A;  3LSN A;  2FOR A;  4NFI F;  5IVG A;  2H8O A;  3BNX A;  4F6X A;  2ZY1 A;  3PYB A;  3SDQ A;  2OPN A;  5JV1 F;  2I19 A;  4LPG F;  5DZ2 A;  3LZ9 A;  3OAB A;  1N23 A;  4KPD A;  5DGM F;  3ADZ A;  3CKE A;  5ILD A;  5IL3 A;  4XQS F;  4ZQ8 A;  2EWG A;  4LXW A;  3TC1 A;  4N9U A;  3SDU A;  3WCL A;  4FP4 A;  1EZF A;  1WL2 A;  5I1U A;  5B01 A;  4RXD A;  3P8L A;  2E4O A;  3OAC A;  4GA3 A;  5ER8 A;  5IL8 A;  3SDV A;  2Z52 A;  5HNA A;  3PKO A;  2Z7I A;  2DH4 A;  2E95 A;  3M01 A;  2ZCS A;  3WCF A;  3QQV A;  1FPS A;  3WJK A;  2OGD A;  3QKC A;  2ONG A;  4MC8 A;  3WSA A;  5B02 A;  1YV5 A;  3IBA A;  3KRP B;  3V1X A;  4N1Z F;  3ZOU A;  1PS1 A;  5E8K A;  3ICM A;  3MZV A;  1N24 A;  4LFE A;  4EA2 A;  5DJP F;  3KRF A; 
#chains in the Genus database with same CATH homology
 4P0W A;  3ICK A;  5EAU A;  1YYS A;  4JZB A;  4JXY A;  2E8T A;  5ILJ A;  3WCD A;  5JV0 F;  3WCA A;  3VJD A;  5IKA A;  1VG6 A;  3LGZ B;  5IKH A;  1HXG A;  3N0G A;  4OMH A;  1JFA A;  3WSB A;  1YHK A;  4NG6 A;  1YHM A;  3N45 F;  3LEE A;  2AZL A;  5B03 A;  4WK5 A;  2Z50 A;  3VJ9 A;  4LIX A;  1YYU A;  4OKZ A;  2PS5 A;  3KB9 A;  5DJR F;  3KRO B;  4DWB A;  3P41 A;  5A0K A;  3S9V A;  5ILH A;  1YYR A;  2AET A;  2RAH A;  5AYP A;  2AEK A;  4LA5 A;  4LZ0 A;  2Z4W A;  4H5E F;  3DYF A;  2O1O A;  3S4J A;  3ASX A;  3G4D A;  3Q2Z A;  2E8X A;  3VJE A;  3WEJ A;  5JV2 F;  5A0J A;  3WCM A;  2Z78 A;  3W7F A;  3LGK A;  4NKF A;  3RYW A;  4E9Z A;  2Q80 A;  3BNY A;  3RYE A;  3WCH A;  3PDE A;  1VG7 A;  3P5P A;  3KRC B;  4QPF A;  1YQ7 A;  3VJA A;  4JYX A;  4LFV F;  4KVW A;  4OKM A;  3WEK A;  4DI5 A;  3EZ3 A;  3PYA A;  3Q1O A;  3M02 A;  4KK2 A;  4QXS F;  5H9D A;  3Q30 A;  3CP6 A;  3LJI A;  4LTZ A;  5B0J A;  5DJV F;  3N3D A;  5IN8 A;  2ZEV A;  3WC9 A;  5HN9 A;  4JVJ F;  1N22 A;  3OAB B;  5ERN A;  2ONH A;  3LDW A;  3ZL6 A;  4LUU A;  1VG3 A;  3N5H F;  5CG6 A;  1HM4 A;  2ZCQ A;  4OGU A;  2F94 F;  2J1O A;  4NFK F;  3AQ0 A;  4XQR F;  2J5C A;  3PH7 A;  3WJO A;  3UCA A;  2Q58 A;  3P5R A;  3LOM A;  4F6V A;  4RYP A;  3V66 A;  1N1B A;  3OAC B;  1KIY A;  5E8H A;  1V4H A;  3KRA A;  2E93 A;  3N46 F;  3V1V A;  2E91 A;  5IMN A;  1V4K A;  4KQU A;  2PS7 A;  5A0I A;  3LVS A;  3N49 F;  4DZW A;  5ILY A;  5JUZ F;  5DGN F;  4H5C F;  4RXE A;  3KRF B;  2AZK A;  4GP2 A;  5IM1 A;  5HN8 A;  4KVY A;  2AEL A;  3KRA B;  3NPK A;  2E8W A;  1UBW A;  3CC9 A;  1RQJ A;  2P1C A;  2Q9Y A;  3WE9 A;  3OYR A;  3SAE A;  4EA1 A;  3G4F A;  4KFA A;  3ID0 A;  5B0K A;  2F9K F;  2VF6 A;  3ZMB A;  2OPM A;  1WKZ A;  3NPR A;  3WCJ A;  3M0G A;  2Z4V A;  3SDR A;  3AE0 A;  4E9U A;  3DYG A;  5B00 A;  4KVD A;  4Q23 A;  5AHU B;  3M9U A;  4KPJ A;  1WL3 A;  5DHI A;  4JXN A;  3IPI A;  3TS7 A;  5AFX A;  3VJ8 A;  3WCB A;  4PVX F;  3DYH A;  5ERO A;  1UBV A;  4KWD A;  5C05 A;  2Z4X A;  4XQT F;  3MAV A;  4E1E A;  3LMD A;  3LG5 A;  4P0V A;  2ZEU A;  1WY0 A;  3N6K F;  2E8V A;  2PS6 A;  1WL0 A;  3SDT A;  1DGP A;  4K10 A;  3WJN A;  3NF2 A;  4H5D F;  4MC3 A;  3M00 A;  4DHD A;  1RQI A;  2Q9Z A;  1UBY A;  3N5J F;  1HXC A;  4GAX A;  4LZC A;  4LA6 A;  2ZCR A;  3N1V F;  4OMG A;  3VJB A;  1N21 A;  4UMJ A;  4LPH F;  4LZ3 A;  2E8U A;  3RBM A;  4NFJ F;  1V4E A;  1ZW5 A;  4GP1 A;  4DEM F;  4F62 A;  5ILI A;  3WCC A;  4LTV A;  5ILK A;  3TFP A;  4KQ5 A;  3LLW A;  1N20 A;  3ICN A;  1WL1 A;  1HX9 A;  1JFG A;  1WMW A;  3APZ A;  5EAT A;  5JA0 F;  3AQC B;  5B0I A;  5HN7 A;  3ACY A;  3KRP A;  3B7L A;  4L2X F;  3WCI A;  3ZCD A;  5IMP A;  2PS4 A;  5IK6 A;  2ZCO A;  5B0M A;  1YJ4 A;  1YHL A;  3WCE A;  2F7M F;  5E8L A;  1YYQ A;  4KUX A;  5ILZ A;  5AEL A;  2F89 F;  5DIQ F;  1KIZ A;  5EAS A;  1N1Z A;  3ACX A;  5DHK A;  1VG4 A;  2QIS A;  4FJQ A;  5KSX F;  2F8C F;  5IK9 A;  3EGT A;  3N3L F;  4DXJ A;  3WEG A;  2Z4Y A;  2Z7H A;  4KKM A;  3TFN A;  5CG5 A;  3VJC A;  4MC0 A;  4HD1 A;  4PVY F;  5IK0 A;  3N0F A;  4LFG A;  1DI1 A;  4KQS A;  3P8R A;  3ACW A;  4LLS A;  3KRO A;  2FTZ A;  2J1P A;  1V4J A;  3ZMC A;  4KVI A;  1UBX A;  3LK5 A;  4RNQ A;  4NKE A;  4NUA A;  4EA0 A;  2E94 A;  4LLT A;  3TFV A;  3KBK A;  3AQB B;  3N1W F;  4RXC A;  3NRI A;  2PS8 A;  5B0L A;  1RTR A;  5IMI A;  1YYT A;  3WEI A;  2OA6 A;  3WEF A;  2F8Z F;  1HM7 A;  4RXA A;  2Z4Z A;  3KRC A;  5DGS F;  2F92 F;  4JZX A;  5ERM A;  2E92 A;  3Q2Q A;  1HXA A;  3EFQ A;  3RMG A;  2AZJ A;  1VG2 A;  3WEH A;  4LOB A;  2E90 A;  4DWG A;  5DW7 A;  4P0X A;  3ICZ A;  1V4I A;  3WCG A;  3LSN A;  2FOR A;  4NFI F;  5IVG A;  2H8O A;  3BNX A;  4F6X A;  2ZY1 A;  3PYB A;  3SDQ A;  2OPN A;  5JV1 F;  2I19 A;  4LPG F;  5DZ2 A;  3LZ9 A;  3OAB A;  1N23 A;  4KPD A;  5DGM F;  3ADZ A;  3CKE A;  5ILD A;  5IL3 A;  4XQS F;  4ZQ8 A;  2EWG A;  4LXW A;  3TC1 A;  4N9U A;  3SDU A;  3WCL A;  4FP4 A;  1EZF A;  1WL2 A;  5I1U A;  5B01 A;  4RXD A;  3P8L A;  2E4O A;  3OAC A;  4GA3 A;  5ER8 A;  5IL8 A;  3SDV A;  2Z52 A;  5HNA A;  3PKO A;  2Z7I A;  2DH4 A;  2E95 A;  3M01 A;  2ZCS A;  3WCF A;  3QQV A;  1FPS A;  3WJK A;  2OGD A;  3QKC A;  2ONG A;  4MC8 A;  3WSA A;  5B02 A;  1YV5 A;  3IBA A;  3KRP B;  3V1X A;  4N1Z F;  3ZOU A;  1PS1 A;  5E8K A;  3ICM A;  3MZV A;  1N24 A;  4LFE A;  4EA2 A;  5DJP F;  3KRF A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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