5DJVF

Crystal structure of human fpps in complex with biaryl compound 8e
Total Genus 125
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
125
sequence length
343
structure length
343
Chain Sequence
DVYAQEKQDFVQHFSQIVRVLTEDEMGHPEIGDAIARLKEVLEYNAIGGKYNRGLTVVVAFRELVEPRKQDADSLQRAWTVGWCVELLQAFFLVADDIMDSSLTRRGQICWYQKPGVGLDAINDANLLEACIYRLLKLYCREQPYYLNLIELFLQSSYQTEIGQTLDLLTAPQGNVDLVRFTEKRYKSIVKYKTAFYSFYLPIAAAMYMAGIDGEKEHANAKKILLEMGEFFQIQDDYLDLFGDPSVTGKIGTDIQDNKCSWLVVQCLQRATPEQYQILKENYGQKEAEKVARVKALYEELDLPAVFLQYEEDSYSHIMALIEQYAAPLPPAVFLGLARKIYK
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Discovery of Novel Allosteric Non-Bisphosphonate Inhibitors of Farnesyl Pyrophosphate Synthase by Integrated Lead Finding.
pubmed doi rcsb
molecule tags Transferase
source organism Homo sapiens
molecule keywords Farnesyl pyrophosphate synthase
total genus 125
structure length 343
sequence length 343
ec nomenclature ec 2.5.1.1: Dimethylallyltranstransferase.
pdb deposition date 2015-09-02

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
F PF00348 polyprenyl_synt Polyprenyl synthetase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.600.10 Mainly Alpha Orthogonal Bundle Farnesyl Diphosphate Synthase Farnesyl Diphosphate Synthase 5djvF00
3SDTA 5A0KA 3N6KF 3EZ3A 3QKCA 2ZY1A 3UCAA 3ADZA 4KVIA 4DZWA 3SDUA 3BNXA 3N5JF 1N1ZA 3DYFA 3KRFB 3WCCA 3WCIA 4LFVF 3W7FA 5ILKA 1HXCA 3KROA 5B00A 3N3LF 3WEHA 5KSXF 1DI1A 4NKEA 1N20A 4RXCA 1N22A 4LXWA 5DHIA 2Q58A 2F8ZF 3M00A 3LEEA 4GP2A 4E1EA 4GA3A 2FORA 4FJQA 3N1WF 5IVGA 4LTZA 3CC9A 2E93A 3Q2QA 4JZBA 5ILZA 1N21A 1VG6A 1HXAA 1VG4A 2PS5A 2ONGA 2E4OA 3LDWA 3PDEA 4LPGF 3SDVA 2Q80A 3IPIA 4RXAA 3ZCDA 3ICZA 4EA2A 2AEKA 2Z4VA 5DHKA 3PYBA 2AELA 3SDRA 5IKHA 3LMDA 1V4IA 2E94A 3EFQA 4JXNA 1WMWA 5B02A 5EROA 4LOBA 3KRCA 5E8HA 3WSAA 4DI5A 2PS8A 4KPJA 5C05A 2Z4ZA 4LA6A 4P0WA 4RNQA 3OABA 3WCFA 4OGUA 4E9ZA 5IK9A 3LG5A 3QQVA 4RXDA 4DWBA 3VJ8A 3WCMA 3LGZB 1YYTA 2Z4YA 2ZEVA 3KROB 4F6VA 1VG3A 3PYAA 5IMNA 2PS6A 1DGPA 3G4FA 3SDQA 4Q23A 3N0FA 4LPHF 3WJNA 5ERNA 4LZCA 4QPFA 4RXEA 5AELA 5HN9A 2F92F 3WE9A 2QISA 2AZJA 2E8TA 3M01A 4JVJF 4F6XA 1V4JA 2E8UA 5JV1F 1WY0A 4MC8A 3Q30A 5B01A 4H5EF 3WEGA 3RYEA 4MC0A 1HX9A 4KVDA 2AZLA 3LVSA 3M0GA 4LUUA 3WEFA 2ZCQA 1UBYA 3LGKA 3AE0A 4NKFA 5IM1A 4NFJF 2I19A 1UBWA 1EZFA 3KBKA 4OKMA 4PVXF 3N0GA 2J1PA 3LLWA 3KRCB 3P5RA 3S4JA 3V1XA 5IL3A 5EATA 5I1UA 5IK6A 3LJIA 5IMPA 5ILYA 3NRIA 4OMGA 3OABB 3BNYA 3AQBB 5B0LA 4HD1A 1JFGA 2Z4XA 5JV2F 3ACYA 1YYQA 4ZQ8A 2PS4A 3PKOA 3IBAA 3WCEA 1VG7A 3B7LA 4NFKF 5DW7A 4N1ZF 4E9UA 4KQUA 3WCAA 4LLTA 5A0IA 2Q9ZA 5B0JA 2OA6A 3P8RA 5B03A 4NG6A 5E8LA 5DGSF 2OPNA 4LZ0A 3OYRA 2F7MF 1HXGA 1JFAA 2E92A 3WC9A 4XQTF 3VJ9A 5HNAA 4LA5A 1YYRA 2E8WA 5ILHA 1YYUA 1WL1A 2Q9YA 2PS7A 4KQ5A 2DH4A 2ZCRA 3ZMCA 2OGDA 4UMJA 3ICNA 1VG2A 1KIYA 4JYXA 2Z7IA 1N1BA 4KK2A 4FP4A 3ID0A 3KRPA 1ZW5A 4EA0A 4LIXA 1HM4A 1YHKA 3KRAA 1N24A 4GAXA 3KB9A 3Q2ZA 3VJBA 4DXJA 3VJAA 3DYHA 2ZCOA 3MZVA 2Z78A 5ERMA 2ONHA 3WJOA 4KKMA 3TS7A 3LOMA 4KUXA 1HM7A 2E8VA 4P0XA 3V1VA 5IL8A 1UBVA 2ZCSA 3WCHA 3WCBA 1KIZA 5ILJA 3RMGA 4N9UA 5ILDA 5A0JA 5EAUA 4RYPA 5DIQF 1PS1A 4KFAA 5DGNF 3AQCB 4OMHA 3M9UA 4KQSA 4WK5A 3WCLA 5JA0F 3DYGA 3G4DA 1UBXA 1V4EA 4H5DF 3OACA 1FPSA 1YHMA 3ACWA 3CKEA 3ZMBA 3WEIA 1WL0A 4NFIF 1V4HA 3WEJA 3TFPA 3NPRA 2E91A 4LZ3A 3P5PA 4LFGA 3KRPB 5B0IA 2FTZA 3WCDA 3WCJA 3KRAB 3SAEA 4LLSA 4JZXA 2Z7HA 3V66A 2F9KF 3LSNA 1YV5A 4DEMF 4NUAA 4KVYA 3LK5A 5HN7A 3M02A 3N1VF 4L2XF 3WJKA 5B0KA 2E95A 4F62A 2VF6A 4DHDA 3N5HF 5DGMF 1RTRA 2AZKA 4LFEA 3EGTA 3ICMA 3NF2A 3AQ0A 3Q1OA 5JV0F 3MAVA 5IKAA 5JUZF 4MC3A 3P41A 3ACXA 2F89F 1YHLA 3WEKA 1V4KA 5CG5A 4PVYF 3OACB 2EWGA 3WSBA 3N45F 3TC1A 1WL3A 3APZA 3N49F 5DJPF 2O1OA 3RBMA 5H9DA 5E8KA 2Z4WA 1WL2A 3N46F 3VJCA 4K10A 3ASXA 4XQRF 4KPDA 4LTVA 1RQJA 3S9VA 3KRFA 2E8XA 3WCGA 5ER8A 3VJEA 4JXYA 2Z50A 4DWGA 1YQ7A 5DJVF 2OPMA 4H5CF 4XQSF 3TFVA 5DZ2A 5B0MA 5ILIA 5IMIA 5EASA 2F94F 1RQIA 1WKZA 3ZL6A 4P0VA 2E90A 3RYWA 3VJDA 3PH7A 3LZ9A 5IK0A 5AFXA 3P8LA 4KVWA 2P1CA 3N3DA 1YJ4A 3CP6A 4OKZA 4QXSF 5AHUB 5AYPA 3NPKA 4KWDA 4EA1A 3ZOUA 3ICKA 5DJRF 2F8CF 2Z52A 5HN8A 2AETA 1N23A 2ZEUA 2J1OA 2J5CA 2RAHA 3TFNA 2H8OA 4GP1A 5CG6A 1YYSA 5IN8A
chains in the Genus database with same CATH superfamily
3SDTA 5A0KA 3N6KF 3EZ3A 3QKCA 2ZY1A 3UCAA 3ADZA 4KVIA 4DZWA 3SDUA 3BNXA 3N5JF 1N1ZA 3DYFA 3KRFB 3WCCA 3WCIA 4LFVF 3W7FA 5ILKA 1HXCA 3KROA 5B00A 3N3LF 3WEHA 5KSXF 1DI1A 4NKEA 1N20A 4RXCA 1N22A 4LXWA 5DHIA 2Q58A 2F8ZF 3M00A 3LEEA 4GP2A 4E1EA 4GA3A 2FORA 4FJQA 3N1WF 5IVGA 4LTZA 3CC9A 2E93A 3Q2QA 4JZBA 5ILZA 1N21A 1VG6A 1HXAA 1VG4A 2PS5A 2ONGA 2E4OA 3LDWA 3PDEA 4LPGF 3SDVA 2Q80A 3IPIA 4RXAA 3ZCDA 3ICZA 4EA2A 2AEKA 2Z4VA 5DHKA 3PYBA 2AELA 3SDRA 5IKHA 3LMDA 1V4IA 2E94A 3EFQA 4JXNA 1WMWA 5B02A 5EROA 4LOBA 3KRCA 5E8HA 3WSAA 4DI5A 2PS8A 4KPJA 5C05A 2Z4ZA 4LA6A 4P0WA 4RNQA 3OABA 3WCFA 4OGUA 4E9ZA 5IK9A 3LG5A 3QQVA 4RXDA 4DWBA 3VJ8A 3WCMA 3LGZB 1YYTA 2Z4YA 2ZEVA 3KROB 4F6VA 1VG3A 3PYAA 5IMNA 2PS6A 1DGPA 3G4FA 3SDQA 4Q23A 3N0FA 4LPHF 3WJNA 5ERNA 4LZCA 4QPFA 4RXEA 5AELA 5HN9A 2F92F 3WE9A 2QISA 2AZJA 2E8TA 3M01A 4JVJF 4F6XA 1V4JA 2E8UA 5JV1F 1WY0A 4MC8A 3Q30A 5B01A 4H5EF 3WEGA 3RYEA 4MC0A 1HX9A 4KVDA 2AZLA 3LVSA 3M0GA 4LUUA 3WEFA 2ZCQA 1UBYA 3LGKA 3AE0A 4NKFA 5IM1A 4NFJF 2I19A 1UBWA 1EZFA 3KBKA 4OKMA 4PVXF 3N0GA 2J1PA 3LLWA 3KRCB 3P5RA 3S4JA 3V1XA 5IL3A 5EATA 5I1UA 5IK6A 3LJIA 5IMPA 5ILYA 3NRIA 4OMGA 3OABB 3BNYA 3AQBB 5B0LA 4HD1A 1JFGA 2Z4XA 5JV2F 3ACYA 1YYQA 4ZQ8A 2PS4A 3PKOA 3IBAA 3WCEA 1VG7A 3B7LA 4NFKF 5DW7A 4N1ZF 4E9UA 4KQUA 3WCAA 4LLTA 5A0IA 2Q9ZA 5B0JA 2OA6A 3P8RA 5B03A 4NG6A 5E8LA 5DGSF 2OPNA 4LZ0A 3OYRA 2F7MF 1HXGA 1JFAA 2E92A 3WC9A 4XQTF 3VJ9A 5HNAA 4LA5A 1YYRA 2E8WA 5ILHA 1YYUA 1WL1A 2Q9YA 2PS7A 4KQ5A 2DH4A 2ZCRA 3ZMCA 2OGDA 4UMJA 3ICNA 1VG2A 1KIYA 4JYXA 2Z7IA 1N1BA 4KK2A 4FP4A 3ID0A 3KRPA 1ZW5A 4EA0A 4LIXA 1HM4A 1YHKA 3KRAA 1N24A 4GAXA 3KB9A 3Q2ZA 3VJBA 4DXJA 3VJAA 3DYHA 2ZCOA 3MZVA 2Z78A 5ERMA 2ONHA 3WJOA 4KKMA 3TS7A 3LOMA 4KUXA 1HM7A 2E8VA 4P0XA 3V1VA 5IL8A 1UBVA 2ZCSA 3WCHA 3WCBA 1KIZA 5ILJA 3RMGA 4N9UA 5ILDA 5A0JA 5EAUA 4RYPA 5DIQF 1PS1A 4KFAA 5DGNF 3AQCB 4OMHA 3M9UA 4KQSA 4WK5A 3WCLA 5JA0F 3DYGA 3G4DA 1UBXA 1V4EA 4H5DF 3OACA 1FPSA 1YHMA 3ACWA 3CKEA 3ZMBA 3WEIA 1WL0A 4NFIF 1V4HA 3WEJA 3TFPA 3NPRA 2E91A 4LZ3A 3P5PA 4LFGA 3KRPB 5B0IA 2FTZA 3WCDA 3WCJA 3KRAB 3SAEA 4LLSA 4JZXA 2Z7HA 3V66A 2F9KF 3LSNA 1YV5A 4DEMF 4NUAA 4KVYA 3LK5A 5HN7A 3M02A 3N1VF 4L2XF 3WJKA 5B0KA 2E95A 4F62A 2VF6A 4DHDA 3N5HF 5DGMF 1RTRA 2AZKA 4LFEA 3EGTA 3ICMA 3NF2A 3AQ0A 3Q1OA 5JV0F 3MAVA 5IKAA 5JUZF 4MC3A 3P41A 3ACXA 2F89F 1YHLA 3WEKA 1V4KA 5CG5A 4PVYF 3OACB 2EWGA 3WSBA 3N45F 3TC1A 1WL3A 3APZA 3N49F 5DJPF 2O1OA 3RBMA 5H9DA 5E8KA 2Z4WA 1WL2A 3N46F 3VJCA 4K10A 3ASXA 4XQRF 4KPDA 4LTVA 1RQJA 3S9VA 3KRFA 2E8XA 3WCGA 5ER8A 3VJEA 4JXYA 2Z50A 4DWGA 1YQ7A 5DJVF 2OPMA 4H5CF 4XQSF 3TFVA 5DZ2A 5B0MA 5ILIA 5IMIA 5EASA 2F94F 1RQIA 1WKZA 3ZL6A 4P0VA 2E90A 3RYWA 3VJDA 3PH7A 3LZ9A 5IK0A 5AFXA 3P8LA 4KVWA 2P1CA 3N3DA 1YJ4A 3CP6A 4OKZA 4QXSF 5AHUB 5AYPA 3NPKA 4KWDA 4EA1A 3ZOUA 3ICKA 5DJRF 2F8CF 2Z52A 5HN8A 2AETA 1N23A 2ZEUA 2J1OA 2J5CA 2RAHA 3TFNA 2H8OA 4GP1A 5CG6A 1YYSA 5IN8A
chains in the Genus database with same CATH topology
3SDTA 5A0KA 3N6KF 3EZ3A 3QKCA 2ZY1A 3UCAA 3ADZA 4KVIA 4DZWA 3SDUA 3BNXA 3N5JF 1N1ZA 3DYFA 3KRFB 3WCCA 3WCIA 4LFVF 3W7FA 5ILKA 1HXCA 3KROA 5B00A 3N3LF 3WEHA 5KSXF 1DI1A 4NKEA 1N20A 4RXCA 1N22A 4LXWA 5DHIA 2Q58A 2F8ZF 3M00A 3LEEA 4GP2A 4E1EA 4GA3A 2FORA 4FJQA 3N1WF 5IVGA 4LTZA 3CC9A 2E93A 3Q2QA 4JZBA 5ILZA 1N21A 1VG6A 1HXAA 1VG4A 2PS5A 2ONGA 2E4OA 3LDWA 3PDEA 4LPGF 3SDVA 2Q80A 3IPIA 4RXAA 3ZCDA 3ICZA 4EA2A 2AEKA 2Z4VA 5DHKA 3PYBA 2AELA 3SDRA 5IKHA 3LMDA 1V4IA 2E94A 3EFQA 4JXNA 1WMWA 5B02A 5EROA 4LOBA 3KRCA 5E8HA 3WSAA 4DI5A 2PS8A 4KPJA 5C05A 2Z4ZA 4LA6A 4P0WA 4RNQA 3OABA 3WCFA 4OGUA 4E9ZA 5IK9A 3LG5A 3QQVA 4RXDA 4DWBA 3VJ8A 3WCMA 3LGZB 1YYTA 2Z4YA 2ZEVA 3KROB 4F6VA 1VG3A 3PYAA 5IMNA 2PS6A 1DGPA 3G4FA 3SDQA 4Q23A 3N0FA 4LPHF 3WJNA 5ERNA 4LZCA 4QPFA 4RXEA 5AELA 5HN9A 2F92F 3WE9A 2QISA 2AZJA 2E8TA 3M01A 4JVJF 4F6XA 1V4JA 2E8UA 5JV1F 1WY0A 4MC8A 3Q30A 5B01A 4H5EF 3WEGA 3RYEA 4MC0A 1HX9A 4KVDA 2AZLA 3LVSA 3M0GA 4LUUA 3WEFA 2ZCQA 1UBYA 3LGKA 3AE0A 4NKFA 5IM1A 4NFJF 2I19A 1UBWA 1EZFA 3KBKA 4OKMA 4PVXF 3N0GA 2J1PA 3LLWA 3KRCB 3P5RA 3S4JA 3V1XA 5IL3A 5EATA 5I1UA 5IK6A 3LJIA 5IMPA 5ILYA 3NRIA 4OMGA 3OABB 3BNYA 3AQBB 5B0LA 4HD1A 1JFGA 2Z4XA 5JV2F 3ACYA 1YYQA 4ZQ8A 2PS4A 3PKOA 3IBAA 3WCEA 1VG7A 3B7LA 4NFKF 5DW7A 4N1ZF 4E9UA 4KQUA 3WCAA 4LLTA 5A0IA 2Q9ZA 5B0JA 2OA6A 3P8RA 5B03A 4NG6A 5E8LA 5DGSF 2OPNA 4LZ0A 3OYRA 2F7MF 1HXGA 1JFAA 2E92A 3WC9A 4XQTF 3VJ9A 5HNAA 4LA5A 1YYRA 2E8WA 5ILHA 1YYUA 1WL1A 2Q9YA 2PS7A 4KQ5A 2DH4A 2ZCRA 3ZMCA 2OGDA 4UMJA 3ICNA 1VG2A 1KIYA 4JYXA 2Z7IA 1N1BA 4KK2A 4FP4A 3ID0A 3KRPA 1ZW5A 4EA0A 4LIXA 1HM4A 1YHKA 3KRAA 1N24A 4GAXA 3KB9A 3Q2ZA 3VJBA 4DXJA 3VJAA 3DYHA 2ZCOA 3MZVA 2Z78A 5ERMA 2ONHA 3WJOA 4KKMA 3TS7A 3LOMA 4KUXA 1HM7A 2E8VA 4P0XA 3V1VA 5IL8A 1UBVA 2ZCSA 3WCHA 3WCBA 1KIZA 5ILJA 3RMGA 4N9UA 5ILDA 5A0JA 5EAUA 4RYPA 5DIQF 1PS1A 4KFAA 5DGNF 3AQCB 4OMHA 3M9UA 4KQSA 4WK5A 3WCLA 5JA0F 3DYGA 3G4DA 1UBXA 1V4EA 4H5DF 3OACA 1FPSA 1YHMA 3ACWA 3CKEA 3ZMBA 3WEIA 1WL0A 4NFIF 1V4HA 3WEJA 3TFPA 3NPRA 2E91A 4LZ3A 3P5PA 4LFGA 3KRPB 5B0IA 2FTZA 3WCDA 3WCJA 3KRAB 3SAEA 4LLSA 4JZXA 2Z7HA 3V66A 2F9KF 3LSNA 1YV5A 4DEMF 4NUAA 4KVYA 3LK5A 5HN7A 3M02A 3N1VF 4L2XF 3WJKA 5B0KA 2E95A 4F62A 2VF6A 4DHDA 3N5HF 5DGMF 1RTRA 2AZKA 4LFEA 3EGTA 3ICMA 3NF2A 3AQ0A 3Q1OA 5JV0F 3MAVA 5IKAA 5JUZF 4MC3A 3P41A 3ACXA 2F89F 1YHLA 3WEKA 1V4KA 5CG5A 4PVYF 3OACB 2EWGA 3WSBA 3N45F 3TC1A 1WL3A 3APZA 3N49F 5DJPF 2O1OA 3RBMA 5H9DA 5E8KA 2Z4WA 1WL2A 3N46F 3VJCA 4K10A 3ASXA 4XQRF 4KPDA 4LTVA 1RQJA 3S9VA 3KRFA 2E8XA 3WCGA 5ER8A 3VJEA 4JXYA 2Z50A 4DWGA 1YQ7A 5DJVF 2OPMA 4H5CF 4XQSF 3TFVA 5DZ2A 5B0MA 5ILIA 5IMIA 5EASA 2F94F 1RQIA 1WKZA 3ZL6A 4P0VA 2E90A 3RYWA 3VJDA 3PH7A 3LZ9A 5IK0A 5AFXA 3P8LA 4KVWA 2P1CA 3N3DA 1YJ4A 3CP6A 4OKZA 4QXSF 5AHUB 5AYPA 3NPKA 4KWDA 4EA1A 3ZOUA 3ICKA 5DJRF 2F8CF 2Z52A 5HN8A 2AETA 1N23A 2ZEUA 2J1OA 2J5CA 2RAHA 3TFNA 2H8OA 4GP1A 5CG6A 1YYSA 5IN8A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3SDT A;  5A0K A;  3N6K F;  3EZ3 A;  3QKC A;  2ZY1 A;  3UCA A;  3ADZ A;  4KVI A;  4DZW A;  3SDU A;  3BNX A;  3N5J F;  1N1Z A;  3DYF A;  3KRF B;  3WCC A;  3WCI A;  4LFV F;  3W7F A;  5ILK A;  1HXC A;  3KRO A;  5B00 A;  3N3L F;  3WEH A;  5KSX F;  1DI1 A;  4NKE A;  1N20 A;  4RXC A;  1N22 A;  4LXW A;  5DHI A;  2Q58 A;  2F8Z F;  3M00 A;  3LEE A;  4GP2 A;  4E1E A;  4GA3 A;  2FOR A;  4FJQ A;  3N1W F;  5IVG A;  4LTZ A;  3CC9 A;  2E93 A;  3Q2Q A;  4JZB A;  5ILZ A;  1N21 A;  1VG6 A;  1HXA A;  1VG4 A;  2PS5 A;  2ONG A;  2E4O A;  3LDW A;  3PDE A;  4LPG F;  3SDV A;  2Q80 A;  3IPI A;  4RXA A;  3ZCD A;  3ICZ A;  4EA2 A;  2AEK A;  2Z4V A;  5DHK A;  3PYB A;  2AEL A;  3SDR A;  5IKH A;  3LMD A;  1V4I A;  2E94 A;  3EFQ A;  4JXN A;  1WMW A;  5B02 A;  5ERO A;  4LOB A;  3KRC A;  5E8H A;  3WSA A;  4DI5 A;  2PS8 A;  4KPJ A;  5C05 A;  2Z4Z A;  4LA6 A;  4P0W A;  4RNQ A;  3OAB A;  3WCF A;  4OGU A;  4E9Z A;  5IK9 A;  3LG5 A;  3QQV A;  4RXD A;  4DWB A;  3VJ8 A;  3WCM A;  3LGZ B;  1YYT A;  2Z4Y A;  2ZEV A;  3KRO B;  4F6V A;  1VG3 A;  3PYA A;  5IMN A;  2PS6 A;  1DGP A;  3G4F A;  3SDQ A;  4Q23 A;  3N0F A;  4LPH F;  3WJN A;  5ERN A;  4LZC A;  4QPF A;  4RXE A;  5AEL A;  5HN9 A;  2F92 F;  3WE9 A;  2QIS A;  2AZJ A;  2E8T A;  3M01 A;  4JVJ F;  4F6X A;  1V4J A;  2E8U A;  5JV1 F;  1WY0 A;  4MC8 A;  3Q30 A;  5B01 A;  4H5E F;  3WEG A;  3RYE A;  4MC0 A;  1HX9 A;  4KVD A;  2AZL A;  3LVS A;  3M0G A;  4LUU A;  3WEF A;  2ZCQ A;  1UBY A;  3LGK A;  3AE0 A;  4NKF A;  5IM1 A;  4NFJ F;  2I19 A;  1UBW A;  1EZF A;  3KBK A;  4OKM A;  4PVX F;  3N0G A;  2J1P A;  3LLW A;  3KRC B;  3P5R A;  3S4J A;  3V1X A;  5IL3 A;  5EAT A;  5I1U A;  5IK6 A;  3LJI A;  5IMP A;  5ILY A;  3NRI A;  4OMG A;  3OAB B;  3BNY A;  3AQB B;  5B0L A;  4HD1 A;  1JFG A;  2Z4X A;  5JV2 F;  3ACY A;  1YYQ A;  4ZQ8 A;  2PS4 A;  3PKO A;  3IBA A;  3WCE A;  1VG7 A;  3B7L A;  4NFK F;  5DW7 A;  4N1Z F;  4E9U A;  4KQU A;  3WCA A;  4LLT A;  5A0I A;  2Q9Z A;  5B0J A;  2OA6 A;  3P8R A;  5B03 A;  4NG6 A;  5E8L A;  5DGS F;  2OPN A;  4LZ0 A;  3OYR A;  2F7M F;  1HXG A;  1JFA A;  2E92 A;  3WC9 A;  4XQT F;  3VJ9 A;  5HNA A;  4LA5 A;  1YYR A;  2E8W A;  5ILH A;  1YYU A;  1WL1 A;  2Q9Y A;  2PS7 A;  4KQ5 A;  2DH4 A;  2ZCR A;  3ZMC A;  2OGD A;  4UMJ A;  3ICN A;  1VG2 A;  1KIY A;  4JYX A;  2Z7I A;  1N1B A;  4KK2 A;  4FP4 A;  3ID0 A;  3KRP A;  1ZW5 A;  4EA0 A;  4LIX A;  1HM4 A;  1YHK A;  3KRA A;  1N24 A;  4GAX A;  3KB9 A;  3Q2Z A;  3VJB A;  4DXJ A;  3VJA A;  3DYH A;  2ZCO A;  3MZV A;  2Z78 A;  5ERM A;  2ONH A;  3WJO A;  4KKM A;  3TS7 A;  3LOM A;  4KUX A;  1HM7 A;  2E8V A;  4P0X A;  3V1V A;  5IL8 A;  1UBV A;  2ZCS A;  3WCH A;  3WCB A;  1KIZ A;  5ILJ A;  3RMG A;  4N9U A;  5ILD A;  5A0J A;  5EAU A;  4RYP A;  5DIQ F;  1PS1 A;  4KFA A;  5DGN F;  3AQC B;  4OMH A;  3M9U A;  4KQS A;  4WK5 A;  3WCL A;  5JA0 F;  3DYG A;  3G4D A;  1UBX A;  1V4E A;  4H5D F;  3OAC A;  1FPS A;  1YHM A;  3ACW A;  3CKE A;  3ZMB A;  3WEI A;  1WL0 A;  4NFI F;  1V4H A;  3WEJ A;  3TFP A;  3NPR A;  2E91 A;  4LZ3 A;  3P5P A;  4LFG A;  3KRP B;  5B0I A;  2FTZ A;  3WCD A;  3WCJ A;  3KRA B;  3SAE A;  4LLS A;  4JZX A;  2Z7H A;  3V66 A;  2F9K F;  3LSN A;  1YV5 A;  4DEM F;  4NUA A;  4KVY A;  3LK5 A;  5HN7 A;  3M02 A;  3N1V F;  4L2X F;  3WJK A;  5B0K A;  2E95 A;  4F62 A;  2VF6 A;  4DHD A;  3N5H F;  5DGM F;  1RTR A;  2AZK A;  4LFE A;  3EGT A;  3ICM A;  3NF2 A;  3AQ0 A;  3Q1O A;  5JV0 F;  3MAV A;  5IKA A;  5JUZ F;  4MC3 A;  3P41 A;  3ACX A;  2F89 F;  1YHL A;  3WEK A;  1V4K A;  5CG5 A;  4PVY F;  3OAC B;  2EWG A;  3WSB A;  3N45 F;  3TC1 A;  1WL3 A;  3APZ A;  3N49 F;  5DJP F;  2O1O A;  3RBM A;  5H9D A;  5E8K A;  2Z4W A;  1WL2 A;  3N46 F;  3VJC A;  4K10 A;  3ASX A;  4XQR F;  4KPD A;  4LTV A;  1RQJ A;  3S9V A;  3KRF A;  2E8X A;  3WCG A;  5ER8 A;  3VJE A;  4JXY A;  2Z50 A;  4DWG A;  1YQ7 A;  5DJV F;  2OPM A;  4H5C F;  4XQS F;  3TFV A;  5DZ2 A;  5B0M A;  5ILI A;  5IMI A;  5EAS A;  2F94 F;  1RQI A;  1WKZ A;  3ZL6 A;  4P0V A;  2E90 A;  3RYW A;  3VJD A;  3PH7 A;  3LZ9 A;  5IK0 A;  5AFX A;  3P8L A;  4KVW A;  2P1C A;  3N3D A;  1YJ4 A;  3CP6 A;  4OKZ A;  4QXS F;  5AHU B;  5AYP A;  3NPK A;  4KWD A;  4EA1 A;  3ZOU A;  3ICK A;  5DJR F;  2F8C F;  2Z52 A;  5HN8 A;  2AET A;  1N23 A;  2ZEU A;  2J1O A;  2J5C A;  2RAH A;  3TFN A;  2H8O A;  4GP1 A;  5CG6 A;  1YYS A;  5IN8 A; 
#chains in the Genus database with same CATH topology
 3SDT A;  5A0K A;  3N6K F;  3EZ3 A;  3QKC A;  2ZY1 A;  3UCA A;  3ADZ A;  4KVI A;  4DZW A;  3SDU A;  3BNX A;  3N5J F;  1N1Z A;  3DYF A;  3KRF B;  3WCC A;  3WCI A;  4LFV F;  3W7F A;  5ILK A;  1HXC A;  3KRO A;  5B00 A;  3N3L F;  3WEH A;  5KSX F;  1DI1 A;  4NKE A;  1N20 A;  4RXC A;  1N22 A;  4LXW A;  5DHI A;  2Q58 A;  2F8Z F;  3M00 A;  3LEE A;  4GP2 A;  4E1E A;  4GA3 A;  2FOR A;  4FJQ A;  3N1W F;  5IVG A;  4LTZ A;  3CC9 A;  2E93 A;  3Q2Q A;  4JZB A;  5ILZ A;  1N21 A;  1VG6 A;  1HXA A;  1VG4 A;  2PS5 A;  2ONG A;  2E4O A;  3LDW A;  3PDE A;  4LPG F;  3SDV A;  2Q80 A;  3IPI A;  4RXA A;  3ZCD A;  3ICZ A;  4EA2 A;  2AEK A;  2Z4V A;  5DHK A;  3PYB A;  2AEL A;  3SDR A;  5IKH A;  3LMD A;  1V4I A;  2E94 A;  3EFQ A;  4JXN A;  1WMW A;  5B02 A;  5ERO A;  4LOB A;  3KRC A;  5E8H A;  3WSA A;  4DI5 A;  2PS8 A;  4KPJ A;  5C05 A;  2Z4Z A;  4LA6 A;  4P0W A;  4RNQ A;  3OAB A;  3WCF A;  4OGU A;  4E9Z A;  5IK9 A;  3LG5 A;  3QQV A;  4RXD A;  4DWB A;  3VJ8 A;  3WCM A;  3LGZ B;  1YYT A;  2Z4Y A;  2ZEV A;  3KRO B;  4F6V A;  1VG3 A;  3PYA A;  5IMN A;  2PS6 A;  1DGP A;  3G4F A;  3SDQ A;  4Q23 A;  3N0F A;  4LPH F;  3WJN A;  5ERN A;  4LZC A;  4QPF A;  4RXE A;  5AEL A;  5HN9 A;  2F92 F;  3WE9 A;  2QIS A;  2AZJ A;  2E8T A;  3M01 A;  4JVJ F;  4F6X A;  1V4J A;  2E8U A;  5JV1 F;  1WY0 A;  4MC8 A;  3Q30 A;  5B01 A;  4H5E F;  3WEG A;  3RYE A;  4MC0 A;  1HX9 A;  4KVD A;  2AZL A;  3LVS A;  3M0G A;  4LUU A;  3WEF A;  2ZCQ A;  1UBY A;  3LGK A;  3AE0 A;  4NKF A;  5IM1 A;  4NFJ F;  2I19 A;  1UBW A;  1EZF A;  3KBK A;  4OKM A;  4PVX F;  3N0G A;  2J1P A;  3LLW A;  3KRC B;  3P5R A;  3S4J A;  3V1X A;  5IL3 A;  5EAT A;  5I1U A;  5IK6 A;  3LJI A;  5IMP A;  5ILY A;  3NRI A;  4OMG A;  3OAB B;  3BNY A;  3AQB B;  5B0L A;  4HD1 A;  1JFG A;  2Z4X A;  5JV2 F;  3ACY A;  1YYQ A;  4ZQ8 A;  2PS4 A;  3PKO A;  3IBA A;  3WCE A;  1VG7 A;  3B7L A;  4NFK F;  5DW7 A;  4N1Z F;  4E9U A;  4KQU A;  3WCA A;  4LLT A;  5A0I A;  2Q9Z A;  5B0J A;  2OA6 A;  3P8R A;  5B03 A;  4NG6 A;  5E8L A;  5DGS F;  2OPN A;  4LZ0 A;  3OYR A;  2F7M F;  1HXG A;  1JFA A;  2E92 A;  3WC9 A;  4XQT F;  3VJ9 A;  5HNA A;  4LA5 A;  1YYR A;  2E8W A;  5ILH A;  1YYU A;  1WL1 A;  2Q9Y A;  2PS7 A;  4KQ5 A;  2DH4 A;  2ZCR A;  3ZMC A;  2OGD A;  4UMJ A;  3ICN A;  1VG2 A;  1KIY A;  4JYX A;  2Z7I A;  1N1B A;  4KK2 A;  4FP4 A;  3ID0 A;  3KRP A;  1ZW5 A;  4EA0 A;  4LIX A;  1HM4 A;  1YHK A;  3KRA A;  1N24 A;  4GAX A;  3KB9 A;  3Q2Z A;  3VJB A;  4DXJ A;  3VJA A;  3DYH A;  2ZCO A;  3MZV A;  2Z78 A;  5ERM A;  2ONH A;  3WJO A;  4KKM A;  3TS7 A;  3LOM A;  4KUX A;  1HM7 A;  2E8V A;  4P0X A;  3V1V A;  5IL8 A;  1UBV A;  2ZCS A;  3WCH A;  3WCB A;  1KIZ A;  5ILJ A;  3RMG A;  4N9U A;  5ILD A;  5A0J A;  5EAU A;  4RYP A;  5DIQ F;  1PS1 A;  4KFA A;  5DGN F;  3AQC B;  4OMH A;  3M9U A;  4KQS A;  4WK5 A;  3WCL A;  5JA0 F;  3DYG A;  3G4D A;  1UBX A;  1V4E A;  4H5D F;  3OAC A;  1FPS A;  1YHM A;  3ACW A;  3CKE A;  3ZMB A;  3WEI A;  1WL0 A;  4NFI F;  1V4H A;  3WEJ A;  3TFP A;  3NPR A;  2E91 A;  4LZ3 A;  3P5P A;  4LFG A;  3KRP B;  5B0I A;  2FTZ A;  3WCD A;  3WCJ A;  3KRA B;  3SAE A;  4LLS A;  4JZX A;  2Z7H A;  3V66 A;  2F9K F;  3LSN A;  1YV5 A;  4DEM F;  4NUA A;  4KVY A;  3LK5 A;  5HN7 A;  3M02 A;  3N1V F;  4L2X F;  3WJK A;  5B0K A;  2E95 A;  4F62 A;  2VF6 A;  4DHD A;  3N5H F;  5DGM F;  1RTR A;  2AZK A;  4LFE A;  3EGT A;  3ICM A;  3NF2 A;  3AQ0 A;  3Q1O A;  5JV0 F;  3MAV A;  5IKA A;  5JUZ F;  4MC3 A;  3P41 A;  3ACX A;  2F89 F;  1YHL A;  3WEK A;  1V4K A;  5CG5 A;  4PVY F;  3OAC B;  2EWG A;  3WSB A;  3N45 F;  3TC1 A;  1WL3 A;  3APZ A;  3N49 F;  5DJP F;  2O1O A;  3RBM A;  5H9D A;  5E8K A;  2Z4W A;  1WL2 A;  3N46 F;  3VJC A;  4K10 A;  3ASX A;  4XQR F;  4KPD A;  4LTV A;  1RQJ A;  3S9V A;  3KRF A;  2E8X A;  3WCG A;  5ER8 A;  3VJE A;  4JXY A;  2Z50 A;  4DWG A;  1YQ7 A;  5DJV F;  2OPM A;  4H5C F;  4XQS F;  3TFV A;  5DZ2 A;  5B0M A;  5ILI A;  5IMI A;  5EAS A;  2F94 F;  1RQI A;  1WKZ A;  3ZL6 A;  4P0V A;  2E90 A;  3RYW A;  3VJD A;  3PH7 A;  3LZ9 A;  5IK0 A;  5AFX A;  3P8L A;  4KVW A;  2P1C A;  3N3D A;  1YJ4 A;  3CP6 A;  4OKZ A;  4QXS F;  5AHU B;  5AYP A;  3NPK A;  4KWD A;  4EA1 A;  3ZOU A;  3ICK A;  5DJR F;  2F8C F;  2Z52 A;  5HN8 A;  2AET A;  1N23 A;  2ZEU A;  2J1O A;  2J5C A;  2RAH A;  3TFN A;  2H8O A;  4GP1 A;  5CG6 A;  1YYS A;  5IN8 A; 
#chains in the Genus database with same CATH homology
 3SDT A;  5A0K A;  3N6K F;  3EZ3 A;  3QKC A;  2ZY1 A;  3UCA A;  3ADZ A;  4KVI A;  4DZW A;  3SDU A;  3BNX A;  3N5J F;  1N1Z A;  3DYF A;  3KRF B;  3WCC A;  3WCI A;  4LFV F;  3W7F A;  5ILK A;  1HXC A;  3KRO A;  5B00 A;  3N3L F;  3WEH A;  5KSX F;  1DI1 A;  4NKE A;  1N20 A;  4RXC A;  1N22 A;  4LXW A;  5DHI A;  2Q58 A;  2F8Z F;  3M00 A;  3LEE A;  4GP2 A;  4E1E A;  4GA3 A;  2FOR A;  4FJQ A;  3N1W F;  5IVG A;  4LTZ A;  3CC9 A;  2E93 A;  3Q2Q A;  4JZB A;  5ILZ A;  1N21 A;  1VG6 A;  1HXA A;  1VG4 A;  2PS5 A;  2ONG A;  2E4O A;  3LDW A;  3PDE A;  4LPG F;  3SDV A;  2Q80 A;  3IPI A;  4RXA A;  3ZCD A;  3ICZ A;  4EA2 A;  2AEK A;  2Z4V A;  5DHK A;  3PYB A;  2AEL A;  3SDR A;  5IKH A;  3LMD A;  1V4I A;  2E94 A;  3EFQ A;  4JXN A;  1WMW A;  5B02 A;  5ERO A;  4LOB A;  3KRC A;  5E8H A;  3WSA A;  4DI5 A;  2PS8 A;  4KPJ A;  5C05 A;  2Z4Z A;  4LA6 A;  4P0W A;  4RNQ A;  3OAB A;  3WCF A;  4OGU A;  4E9Z A;  5IK9 A;  3LG5 A;  3QQV A;  4RXD A;  4DWB A;  3VJ8 A;  3WCM A;  3LGZ B;  1YYT A;  2Z4Y A;  2ZEV A;  3KRO B;  4F6V A;  1VG3 A;  3PYA A;  5IMN A;  2PS6 A;  1DGP A;  3G4F A;  3SDQ A;  4Q23 A;  3N0F A;  4LPH F;  3WJN A;  5ERN A;  4LZC A;  4QPF A;  4RXE A;  5AEL A;  5HN9 A;  2F92 F;  3WE9 A;  2QIS A;  2AZJ A;  2E8T A;  3M01 A;  4JVJ F;  4F6X A;  1V4J A;  2E8U A;  5JV1 F;  1WY0 A;  4MC8 A;  3Q30 A;  5B01 A;  4H5E F;  3WEG A;  3RYE A;  4MC0 A;  1HX9 A;  4KVD A;  2AZL A;  3LVS A;  3M0G A;  4LUU A;  3WEF A;  2ZCQ A;  1UBY A;  3LGK A;  3AE0 A;  4NKF A;  5IM1 A;  4NFJ F;  2I19 A;  1UBW A;  1EZF A;  3KBK A;  4OKM A;  4PVX F;  3N0G A;  2J1P A;  3LLW A;  3KRC B;  3P5R A;  3S4J A;  3V1X A;  5IL3 A;  5EAT A;  5I1U A;  5IK6 A;  3LJI A;  5IMP A;  5ILY A;  3NRI A;  4OMG A;  3OAB B;  3BNY A;  3AQB B;  5B0L A;  4HD1 A;  1JFG A;  2Z4X A;  5JV2 F;  3ACY A;  1YYQ A;  4ZQ8 A;  2PS4 A;  3PKO A;  3IBA A;  3WCE A;  1VG7 A;  3B7L A;  4NFK F;  5DW7 A;  4N1Z F;  4E9U A;  4KQU A;  3WCA A;  4LLT A;  5A0I A;  2Q9Z A;  5B0J A;  2OA6 A;  3P8R A;  5B03 A;  4NG6 A;  5E8L A;  5DGS F;  2OPN A;  4LZ0 A;  3OYR A;  2F7M F;  1HXG A;  1JFA A;  2E92 A;  3WC9 A;  4XQT F;  3VJ9 A;  5HNA A;  4LA5 A;  1YYR A;  2E8W A;  5ILH A;  1YYU A;  1WL1 A;  2Q9Y A;  2PS7 A;  4KQ5 A;  2DH4 A;  2ZCR A;  3ZMC A;  2OGD A;  4UMJ A;  3ICN A;  1VG2 A;  1KIY A;  4JYX A;  2Z7I A;  1N1B A;  4KK2 A;  4FP4 A;  3ID0 A;  3KRP A;  1ZW5 A;  4EA0 A;  4LIX A;  1HM4 A;  1YHK A;  3KRA A;  1N24 A;  4GAX A;  3KB9 A;  3Q2Z A;  3VJB A;  4DXJ A;  3VJA A;  3DYH A;  2ZCO A;  3MZV A;  2Z78 A;  5ERM A;  2ONH A;  3WJO A;  4KKM A;  3TS7 A;  3LOM A;  4KUX A;  1HM7 A;  2E8V A;  4P0X A;  3V1V A;  5IL8 A;  1UBV A;  2ZCS A;  3WCH A;  3WCB A;  1KIZ A;  5ILJ A;  3RMG A;  4N9U A;  5ILD A;  5A0J A;  5EAU A;  4RYP A;  5DIQ F;  1PS1 A;  4KFA A;  5DGN F;  3AQC B;  4OMH A;  3M9U A;  4KQS A;  4WK5 A;  3WCL A;  5JA0 F;  3DYG A;  3G4D A;  1UBX A;  1V4E A;  4H5D F;  3OAC A;  1FPS A;  1YHM A;  3ACW A;  3CKE A;  3ZMB A;  3WEI A;  1WL0 A;  4NFI F;  1V4H A;  3WEJ A;  3TFP A;  3NPR A;  2E91 A;  4LZ3 A;  3P5P A;  4LFG A;  3KRP B;  5B0I A;  2FTZ A;  3WCD A;  3WCJ A;  3KRA B;  3SAE A;  4LLS A;  4JZX A;  2Z7H A;  3V66 A;  2F9K F;  3LSN A;  1YV5 A;  4DEM F;  4NUA A;  4KVY A;  3LK5 A;  5HN7 A;  3M02 A;  3N1V F;  4L2X F;  3WJK A;  5B0K A;  2E95 A;  4F62 A;  2VF6 A;  4DHD A;  3N5H F;  5DGM F;  1RTR A;  2AZK A;  4LFE A;  3EGT A;  3ICM A;  3NF2 A;  3AQ0 A;  3Q1O A;  5JV0 F;  3MAV A;  5IKA A;  5JUZ F;  4MC3 A;  3P41 A;  3ACX A;  2F89 F;  1YHL A;  3WEK A;  1V4K A;  5CG5 A;  4PVY F;  3OAC B;  2EWG A;  3WSB A;  3N45 F;  3TC1 A;  1WL3 A;  3APZ A;  3N49 F;  5DJP F;  2O1O A;  3RBM A;  5H9D A;  5E8K A;  2Z4W A;  1WL2 A;  3N46 F;  3VJC A;  4K10 A;  3ASX A;  4XQR F;  4KPD A;  4LTV A;  1RQJ A;  3S9V A;  3KRF A;  2E8X A;  3WCG A;  5ER8 A;  3VJE A;  4JXY A;  2Z50 A;  4DWG A;  1YQ7 A;  5DJV F;  2OPM A;  4H5C F;  4XQS F;  3TFV A;  5DZ2 A;  5B0M A;  5ILI A;  5IMI A;  5EAS A;  2F94 F;  1RQI A;  1WKZ A;  3ZL6 A;  4P0V A;  2E90 A;  3RYW A;  3VJD A;  3PH7 A;  3LZ9 A;  5IK0 A;  5AFX A;  3P8L A;  4KVW A;  2P1C A;  3N3D A;  1YJ4 A;  3CP6 A;  4OKZ A;  4QXS F;  5AHU B;  5AYP A;  3NPK A;  4KWD A;  4EA1 A;  3ZOU A;  3ICK A;  5DJR F;  2F8C F;  2Z52 A;  5HN8 A;  2AET A;  1N23 A;  2ZEU A;  2J1O A;  2J5C A;  2RAH A;  3TFN A;  2H8O A;  4GP1 A;  5CG6 A;  1YYS A;  5IN8 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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