5KSXF

Crystal structure of human fpps in complex with an allosteric inhibitor am-02-072
Total Genus 132
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
132
sequence length
343
structure length
339
Chain Sequence
VYAQEKQDFVQHFSQIVRVLTEGHPEIGDAIARLKEVLEYNAIGGKYNRGLTVVVAFRELVEPRKQDADSLQRAWTVGWCVELLQAFFLVADDIMDSSLTRRGQICWYQKPGVGLDAINDANLLEACIYRLLKLYCREQPYYLNLIELFLQSSYQTEIGQTLDLLTAPQNVDLVRFTEKRYKSIVKYKTAFYSFYLPIAAAMYMAGIDGEKEHANAKKILLEMGEFFQIQDDYLDLFGDPSVTGKIGTDIQDNKCSWLVVQCLQRATPEQYQILKENYGQKEAEKVARVKALYEELDLPAVFLQYEEDSYSHIMALIEQYAAPLPPAVFLGLARKIYKR
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Pharmacophore Mapping of Thienopyrimidine-Based Monophosphonate (ThP-MP) Inhibitors of the Human Farnesyl Pyrophosphate Synthase.
pubmed doi rcsb
molecule tags Transferase/transferase inhibitor
source organism Homo sapiens
molecule keywords Farnesyl pyrophosphate synthase
total genus 132
structure length 339
sequence length 343
ec nomenclature ec 2.5.1.1: Dimethylallyltranstransferase.
pdb deposition date 2016-07-10

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
F PF00348 polyprenyl_synt Polyprenyl synthetase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.600.10 Mainly Alpha Orthogonal Bundle Farnesyl Diphosphate Synthase Farnesyl Diphosphate Synthase 5ksxF00
4MC8A 3LOMA 3MZVA 2E91A 2ZEUA 3MAVA 3N49F 2Q9ZA 2VF6A 3PH7A 5E8KA 4P0VA 5B0IA 4DHDA 3NF2A 3DYHA 3WCHA 4GP2A 3S4JA 4NG6A 3WCJA 1VG3A 5B03A 3QQVA 5ILDA 3TC1A 1WKZA 4NFJF 2AELA 4LZCA 1VG2A 3ASXA 5CG5A 4KPJA 5HNAA 3ICMA 2O1OA 3ZL6A 3P5RA 1N23A 3BNXA 3WCEA 5IKAA 5IMNA 3ACYA 1UBVA 2FTZA 1YYUA 3N6KF 2Q58A 5DGNF 3TFNA 4LPGF 3DYGA 4KUXA 3N46F 4LUUA 4JYXA 4XQTF 3VJDA 3LZ9A 2OGDA 1VG6A 2PS8A 4LFVF 2Z50A 1HM4A 1N22A 4GA3A 3LK5A 3Q1OA 1N20A 3VJ9A 1V4KA 4DXJA 3PYBA 1PS1A 4GP1A 4JZXA 5B00A 3P41A 2E90A 3SDUA 4JXYA 3WEIA 2H8OA 3M0GA 4K10A 2E94A 3M01A 2E8VA 1KIYA 5B0LA 2PS7A 3KROB 4L2XF 1UBXA 3LMDA 5ILIA 4E1EA 2P1CA 1YYSA 3APZA 4LLTA 3SDVA 1WL1A 3NRIA 5IKHA 3S9VA 3KROA 2I19A 1V4EA 4OMHA 3N5HF 2AZJA 4UMJA 5DJPF 3SAEA 4LPHF 5ERMA 4LZ0A 1HXGA 2AZKA 4RYPA 1N1ZA 2Z4WA 2Z78A 2ZCOA 5CG6A 5EATA 3ZMBA 3KBKA 5ILZA 2Q80A 4GAXA 3AQ0A 3WJNA 2Z52A 3LSNA 4EA1A 4EA0A 3PKOA 5DIQF 4LIXA 5HN9A 2Z4XA 3OABB 5IN8A 2AZLA 3AQBB 3NPKA 3M02A 3EGTA 1N1BA 1RQJA 4XQRF 5HN7A 2AEKA 3WCGA 4NFKF 4FP4A 3ZCDA 3V1XA 3OABA 3RMGA 3ID0A 2J1OA 4P0WA 2J5CA 4LTZA 4RXAA 3RYWA 2Z4YA 3WEHA 1HXCA 4MC0A 3WCDA 4DWBA 5EAUA 3KRAB 4F62A 1UBYA 3WEFA 3WCFA 5A0IA 3PYAA 2DH4A 4JZBA 3ACWA 3G4FA 5JUZF 3WEKA 1N24A 5B02A 2Z7HA 3M00A 5A0JA 3M9UA 5JV1F 2F8ZF 5EASA 4P0XA 3KRAA 4QPFA 3SDRA 1JFAA 3ACXA 1HX9A 3DYFA 2J1PA 1YYQA 4QXSF 4FJQA 4N1ZF 2ZCQA 5ILKA 5ILYA 4WK5A 3WE9A 4H5DF 2ZCRA 1YJ4A 1WL0A 3WCMA 3ZOUA 2F92F 3P8RA 3SDTA 4LA6A 5DZ2A 2Q9YA 4LZ3A 2F9KF 2RAHA 3WCAA 4KWDA 2ONHA 4PVYF 4KQSA 5IMPA 1YHKA 3AQCB 3LJIA 4OKMA 4E9ZA 4PVXF 3UCAA 4LTVA 1V4HA 1YV5A 3Q30A 3WC9A 3BNYA 3NPRA 3P5PA 3QKCA 3WSAA 3N5JF 2F7MF 3WCIA 1EZFA 4DEMF 2E8UA 2ZY1A 4H5EF 3N45F 3PDEA 2E8XA 2OPNA 5E8LA 4MC3A 1VG4A 3ICZA 3VJAA 4NKEA 3N0GA 3LGZB 3P8LA 4KVDA 2OPMA 4E9UA 4KFAA 3KB9A 5IL3A 2ZCSA 4KQ5A 4N9UA 5A0KA 1YQ7A 5IK6A 2Z7IA 3VJBA 4OMGA 3IPIA 1YYTA 3V1VA 3LDWA 1YHLA 5DGMF 2AETA 5IL8A 3VJEA 4F6XA 5EROA 5ILHA 5B01A 5H9DA 1DI1A 3VJCA 3Q2QA 3LLWA 4NKFA 5JV2F 4NFIF 4RXDA 1ZW5A 3WSBA 4LXWA 4KVIA 3WJKA 5E8HA 3RBMA 2F89F 3VJ8A 3KRFB 5HN8A 3LVSA 3ICKA 3WEGA 1WMWA 1N21A 3WCLA 5B0KA 3LEEA 2E8WA 3ICNA 3IBAA 4DZWA 4EA2A 3KRFA 5B0MA 4KVYA 4JXNA 4LFEA 5AELA 2F94F 1JFGA 2F8CF 4XQSF 3KRCB 3EZ3A 4RXEA 5IVGA 4KPDA 5ER8A 1UBWA 1RQIA 3KRCA 4RXCA 4Q23A 4KVWA 3KRPB 3N3DA 5ERNA 1YYRA 1HM7A 3WCBA 5IK9A 2PS6A 3CKEA 4JVJF 5IK0A 3SDQA 5DHIA 3CP6A 2FORA 1HXAA 3WCCA 3TS7A 3KRPA 4DWGA 2E4OA 5I1UA 3B7LA 3AE0A 3WJOA 2Z4VA 3OACB 2OA6A 4LA5A 2E95A 5AHUB 4DI5A 2E93A 3LG5A 1FPSA 3RYEA 3N1WF 1WL3A 5AYPA 3Q2ZA 3OACA 2PS4A 2EWGA 5JA0F 2PS5A 2ZEVA 4KKMA 4NUAA 4HD1A 4LLSA 4LFGA 2Z4ZA 4KQUA 5C05A 1VG7A 1V4IA 3N0FA 3G4DA 2QISA 1WL2A 4KK2A 5KSXF 1V4JA 3OYRA 5DJRF 3W7FA 3N1VF 3ZMCA 3EFQA 4OKZA 5AFXA 5JV0F 3TFPA 2E92A 1RTRA 2ONGA 4H5CF 5DJVF 5IMIA 3ADZA 1DGPA 4ZQ8A 1KIZA 1YHMA 5DGSF 4OGUA 4F6VA 3N3LF 2E8TA 5DHKA 1WY0A 5DW7A 3CC9A 3V66A 5B0JA 3WEJA 4RNQA 5IM1A 5ILJA 3TFVA 3LGKA 4LOBA
chains in the Genus database with same CATH superfamily
4MC8A 3LOMA 3MZVA 2E91A 2ZEUA 3MAVA 3N49F 2Q9ZA 2VF6A 3PH7A 5E8KA 4P0VA 5B0IA 4DHDA 3NF2A 3DYHA 3WCHA 4GP2A 3S4JA 4NG6A 3WCJA 1VG3A 5B03A 3QQVA 5ILDA 3TC1A 1WKZA 4NFJF 2AELA 4LZCA 1VG2A 3ASXA 5CG5A 4KPJA 5HNAA 3ICMA 2O1OA 3ZL6A 3P5RA 1N23A 3BNXA 3WCEA 5IKAA 5IMNA 3ACYA 1UBVA 2FTZA 1YYUA 3N6KF 2Q58A 5DGNF 3TFNA 4LPGF 3DYGA 4KUXA 3N46F 4LUUA 4JYXA 4XQTF 3VJDA 3LZ9A 2OGDA 1VG6A 2PS8A 4LFVF 2Z50A 1HM4A 1N22A 4GA3A 3LK5A 3Q1OA 1N20A 3VJ9A 1V4KA 4DXJA 3PYBA 1PS1A 4GP1A 4JZXA 5B00A 3P41A 2E90A 3SDUA 4JXYA 3WEIA 2H8OA 3M0GA 4K10A 2E94A 3M01A 2E8VA 1KIYA 5B0LA 2PS7A 3KROB 4L2XF 1UBXA 3LMDA 5ILIA 4E1EA 2P1CA 1YYSA 3APZA 4LLTA 3SDVA 1WL1A 3NRIA 5IKHA 3S9VA 3KROA 2I19A 1V4EA 4OMHA 3N5HF 2AZJA 4UMJA 5DJPF 3SAEA 4LPHF 5ERMA 4LZ0A 1HXGA 2AZKA 4RYPA 1N1ZA 2Z4WA 2Z78A 2ZCOA 5CG6A 5EATA 3ZMBA 3KBKA 5ILZA 2Q80A 4GAXA 3AQ0A 3WJNA 2Z52A 3LSNA 4EA1A 4EA0A 3PKOA 5DIQF 4LIXA 5HN9A 2Z4XA 3OABB 5IN8A 2AZLA 3AQBB 3NPKA 3M02A 3EGTA 1N1BA 1RQJA 4XQRF 5HN7A 2AEKA 3WCGA 4NFKF 4FP4A 3ZCDA 3V1XA 3OABA 3RMGA 3ID0A 2J1OA 4P0WA 2J5CA 4LTZA 4RXAA 3RYWA 2Z4YA 3WEHA 1HXCA 4MC0A 3WCDA 4DWBA 5EAUA 3KRAB 4F62A 1UBYA 3WEFA 3WCFA 5A0IA 3PYAA 2DH4A 4JZBA 3ACWA 3G4FA 5JUZF 3WEKA 1N24A 5B02A 2Z7HA 3M00A 5A0JA 3M9UA 5JV1F 2F8ZF 5EASA 4P0XA 3KRAA 4QPFA 3SDRA 1JFAA 3ACXA 1HX9A 3DYFA 2J1PA 1YYQA 4QXSF 4FJQA 4N1ZF 2ZCQA 5ILKA 5ILYA 4WK5A 3WE9A 4H5DF 2ZCRA 1YJ4A 1WL0A 3WCMA 3ZOUA 2F92F 3P8RA 3SDTA 4LA6A 5DZ2A 2Q9YA 4LZ3A 2F9KF 2RAHA 3WCAA 4KWDA 2ONHA 4PVYF 4KQSA 5IMPA 1YHKA 3AQCB 3LJIA 4OKMA 4E9ZA 4PVXF 3UCAA 4LTVA 1V4HA 1YV5A 3Q30A 3WC9A 3BNYA 3NPRA 3P5PA 3QKCA 3WSAA 3N5JF 2F7MF 3WCIA 1EZFA 4DEMF 2E8UA 2ZY1A 4H5EF 3N45F 3PDEA 2E8XA 2OPNA 5E8LA 4MC3A 1VG4A 3ICZA 3VJAA 4NKEA 3N0GA 3LGZB 3P8LA 4KVDA 2OPMA 4E9UA 4KFAA 3KB9A 5IL3A 2ZCSA 4KQ5A 4N9UA 5A0KA 1YQ7A 5IK6A 2Z7IA 3VJBA 4OMGA 3IPIA 1YYTA 3V1VA 3LDWA 1YHLA 5DGMF 2AETA 5IL8A 3VJEA 4F6XA 5EROA 5ILHA 5B01A 5H9DA 1DI1A 3VJCA 3Q2QA 3LLWA 4NKFA 5JV2F 4NFIF 4RXDA 1ZW5A 3WSBA 4LXWA 4KVIA 3WJKA 5E8HA 3RBMA 2F89F 3VJ8A 3KRFB 5HN8A 3LVSA 3ICKA 3WEGA 1WMWA 1N21A 3WCLA 5B0KA 3LEEA 2E8WA 3ICNA 3IBAA 4DZWA 4EA2A 3KRFA 5B0MA 4KVYA 4JXNA 4LFEA 5AELA 2F94F 1JFGA 2F8CF 4XQSF 3KRCB 3EZ3A 4RXEA 5IVGA 4KPDA 5ER8A 1UBWA 1RQIA 3KRCA 4RXCA 4Q23A 4KVWA 3KRPB 3N3DA 5ERNA 1YYRA 1HM7A 3WCBA 5IK9A 2PS6A 3CKEA 4JVJF 5IK0A 3SDQA 5DHIA 3CP6A 2FORA 1HXAA 3WCCA 3TS7A 3KRPA 4DWGA 2E4OA 5I1UA 3B7LA 3AE0A 3WJOA 2Z4VA 3OACB 2OA6A 4LA5A 2E95A 5AHUB 4DI5A 2E93A 3LG5A 1FPSA 3RYEA 3N1WF 1WL3A 5AYPA 3Q2ZA 3OACA 2PS4A 2EWGA 5JA0F 2PS5A 2ZEVA 4KKMA 4NUAA 4HD1A 4LLSA 4LFGA 2Z4ZA 4KQUA 5C05A 1VG7A 1V4IA 3N0FA 3G4DA 2QISA 1WL2A 4KK2A 5KSXF 1V4JA 3OYRA 5DJRF 3W7FA 3N1VF 3ZMCA 3EFQA 4OKZA 5AFXA 5JV0F 3TFPA 2E92A 1RTRA 2ONGA 4H5CF 5DJVF 5IMIA 3ADZA 1DGPA 4ZQ8A 1KIZA 1YHMA 5DGSF 4OGUA 4F6VA 3N3LF 2E8TA 5DHKA 1WY0A 5DW7A 3CC9A 3V66A 5B0JA 3WEJA 4RNQA 5IM1A 5ILJA 3TFVA 3LGKA 4LOBA
chains in the Genus database with same CATH topology
4MC8A 3LOMA 3MZVA 2E91A 2ZEUA 3MAVA 3N49F 2Q9ZA 2VF6A 3PH7A 5E8KA 4P0VA 5B0IA 4DHDA 3NF2A 3DYHA 3WCHA 4GP2A 3S4JA 4NG6A 3WCJA 1VG3A 5B03A 3QQVA 5ILDA 3TC1A 1WKZA 4NFJF 2AELA 4LZCA 1VG2A 3ASXA 5CG5A 4KPJA 5HNAA 3ICMA 2O1OA 3ZL6A 3P5RA 1N23A 3BNXA 3WCEA 5IKAA 5IMNA 3ACYA 1UBVA 2FTZA 1YYUA 3N6KF 2Q58A 5DGNF 3TFNA 4LPGF 3DYGA 4KUXA 3N46F 4LUUA 4JYXA 4XQTF 3VJDA 3LZ9A 2OGDA 1VG6A 2PS8A 4LFVF 2Z50A 1HM4A 1N22A 4GA3A 3LK5A 3Q1OA 1N20A 3VJ9A 1V4KA 4DXJA 3PYBA 1PS1A 4GP1A 4JZXA 5B00A 3P41A 2E90A 3SDUA 4JXYA 3WEIA 2H8OA 3M0GA 4K10A 2E94A 3M01A 2E8VA 1KIYA 5B0LA 2PS7A 3KROB 4L2XF 1UBXA 3LMDA 5ILIA 4E1EA 2P1CA 1YYSA 3APZA 4LLTA 3SDVA 1WL1A 3NRIA 5IKHA 3S9VA 3KROA 2I19A 1V4EA 4OMHA 3N5HF 2AZJA 4UMJA 5DJPF 3SAEA 4LPHF 5ERMA 4LZ0A 1HXGA 2AZKA 4RYPA 1N1ZA 2Z4WA 2Z78A 2ZCOA 5CG6A 5EATA 3ZMBA 3KBKA 5ILZA 2Q80A 4GAXA 3AQ0A 3WJNA 2Z52A 3LSNA 4EA1A 4EA0A 3PKOA 5DIQF 4LIXA 5HN9A 2Z4XA 3OABB 5IN8A 2AZLA 3AQBB 3NPKA 3M02A 3EGTA 1N1BA 1RQJA 4XQRF 5HN7A 2AEKA 3WCGA 4NFKF 4FP4A 3ZCDA 3V1XA 3OABA 3RMGA 3ID0A 2J1OA 4P0WA 2J5CA 4LTZA 4RXAA 3RYWA 2Z4YA 3WEHA 1HXCA 4MC0A 3WCDA 4DWBA 5EAUA 3KRAB 4F62A 1UBYA 3WEFA 3WCFA 5A0IA 3PYAA 2DH4A 4JZBA 3ACWA 3G4FA 5JUZF 3WEKA 1N24A 5B02A 2Z7HA 3M00A 5A0JA 3M9UA 5JV1F 2F8ZF 5EASA 4P0XA 3KRAA 4QPFA 3SDRA 1JFAA 3ACXA 1HX9A 3DYFA 2J1PA 1YYQA 4QXSF 4FJQA 4N1ZF 2ZCQA 5ILKA 5ILYA 4WK5A 3WE9A 4H5DF 2ZCRA 1YJ4A 1WL0A 3WCMA 3ZOUA 2F92F 3P8RA 3SDTA 4LA6A 5DZ2A 2Q9YA 4LZ3A 2F9KF 2RAHA 3WCAA 4KWDA 2ONHA 4PVYF 4KQSA 5IMPA 1YHKA 3AQCB 3LJIA 4OKMA 4E9ZA 4PVXF 3UCAA 4LTVA 1V4HA 1YV5A 3Q30A 3WC9A 3BNYA 3NPRA 3P5PA 3QKCA 3WSAA 3N5JF 2F7MF 3WCIA 1EZFA 4DEMF 2E8UA 2ZY1A 4H5EF 3N45F 3PDEA 2E8XA 2OPNA 5E8LA 4MC3A 1VG4A 3ICZA 3VJAA 4NKEA 3N0GA 3LGZB 3P8LA 4KVDA 2OPMA 4E9UA 4KFAA 3KB9A 5IL3A 2ZCSA 4KQ5A 4N9UA 5A0KA 1YQ7A 5IK6A 2Z7IA 3VJBA 4OMGA 3IPIA 1YYTA 3V1VA 3LDWA 1YHLA 5DGMF 2AETA 5IL8A 3VJEA 4F6XA 5EROA 5ILHA 5B01A 5H9DA 1DI1A 3VJCA 3Q2QA 3LLWA 4NKFA 5JV2F 4NFIF 4RXDA 1ZW5A 3WSBA 4LXWA 4KVIA 3WJKA 5E8HA 3RBMA 2F89F 3VJ8A 3KRFB 5HN8A 3LVSA 3ICKA 3WEGA 1WMWA 1N21A 3WCLA 5B0KA 3LEEA 2E8WA 3ICNA 3IBAA 4DZWA 4EA2A 3KRFA 5B0MA 4KVYA 4JXNA 4LFEA 5AELA 2F94F 1JFGA 2F8CF 4XQSF 3KRCB 3EZ3A 4RXEA 5IVGA 4KPDA 5ER8A 1UBWA 1RQIA 3KRCA 4RXCA 4Q23A 4KVWA 3KRPB 3N3DA 5ERNA 1YYRA 1HM7A 3WCBA 5IK9A 2PS6A 3CKEA 4JVJF 5IK0A 3SDQA 5DHIA 3CP6A 2FORA 1HXAA 3WCCA 3TS7A 3KRPA 4DWGA 2E4OA 5I1UA 3B7LA 3AE0A 3WJOA 2Z4VA 3OACB 2OA6A 4LA5A 2E95A 5AHUB 4DI5A 2E93A 3LG5A 1FPSA 3RYEA 3N1WF 1WL3A 5AYPA 3Q2ZA 3OACA 2PS4A 2EWGA 5JA0F 2PS5A 2ZEVA 4KKMA 4NUAA 4HD1A 4LLSA 4LFGA 2Z4ZA 4KQUA 5C05A 1VG7A 1V4IA 3N0FA 3G4DA 2QISA 1WL2A 4KK2A 5KSXF 1V4JA 3OYRA 5DJRF 3W7FA 3N1VF 3ZMCA 3EFQA 4OKZA 5AFXA 5JV0F 3TFPA 2E92A 1RTRA 2ONGA 4H5CF 5DJVF 5IMIA 3ADZA 1DGPA 4ZQ8A 1KIZA 1YHMA 5DGSF 4OGUA 4F6VA 3N3LF 2E8TA 5DHKA 1WY0A 5DW7A 3CC9A 3V66A 5B0JA 3WEJA 4RNQA 5IM1A 5ILJA 3TFVA 3LGKA 4LOBA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4MC8 A;  3LOM A;  3MZV A;  2E91 A;  2ZEU A;  3MAV A;  3N49 F;  2Q9Z A;  2VF6 A;  3PH7 A;  5E8K A;  4P0V A;  5B0I A;  4DHD A;  3NF2 A;  3DYH A;  3WCH A;  4GP2 A;  3S4J A;  4NG6 A;  3WCJ A;  1VG3 A;  5B03 A;  3QQV A;  5ILD A;  3TC1 A;  1WKZ A;  4NFJ F;  2AEL A;  4LZC A;  1VG2 A;  3ASX A;  5CG5 A;  4KPJ A;  5HNA A;  3ICM A;  2O1O A;  3ZL6 A;  3P5R A;  1N23 A;  3BNX A;  3WCE A;  5IKA A;  5IMN A;  3ACY A;  1UBV A;  2FTZ A;  1YYU A;  3N6K F;  2Q58 A;  5DGN F;  3TFN A;  4LPG F;  3DYG A;  4KUX A;  3N46 F;  4LUU A;  4JYX A;  4XQT F;  3VJD A;  3LZ9 A;  2OGD A;  1VG6 A;  2PS8 A;  4LFV F;  2Z50 A;  1HM4 A;  1N22 A;  4GA3 A;  3LK5 A;  3Q1O A;  1N20 A;  3VJ9 A;  1V4K A;  4DXJ A;  3PYB A;  1PS1 A;  4GP1 A;  4JZX A;  5B00 A;  3P41 A;  2E90 A;  3SDU A;  4JXY A;  3WEI A;  2H8O A;  3M0G A;  4K10 A;  2E94 A;  3M01 A;  2E8V A;  1KIY A;  5B0L A;  2PS7 A;  3KRO B;  4L2X F;  1UBX A;  3LMD A;  5ILI A;  4E1E A;  2P1C A;  1YYS A;  3APZ A;  4LLT A;  3SDV A;  1WL1 A;  3NRI A;  5IKH A;  3S9V A;  3KRO A;  2I19 A;  1V4E A;  4OMH A;  3N5H F;  2AZJ A;  4UMJ A;  5DJP F;  3SAE A;  4LPH F;  5ERM A;  4LZ0 A;  1HXG A;  2AZK A;  4RYP A;  1N1Z A;  2Z4W A;  2Z78 A;  2ZCO A;  5CG6 A;  5EAT A;  3ZMB A;  3KBK A;  5ILZ A;  2Q80 A;  4GAX A;  3AQ0 A;  3WJN A;  2Z52 A;  3LSN A;  4EA1 A;  4EA0 A;  3PKO A;  5DIQ F;  4LIX A;  5HN9 A;  2Z4X A;  3OAB B;  5IN8 A;  2AZL A;  3AQB B;  3NPK A;  3M02 A;  3EGT A;  1N1B A;  1RQJ A;  4XQR F;  5HN7 A;  2AEK A;  3WCG A;  4NFK F;  4FP4 A;  3ZCD A;  3V1X A;  3OAB A;  3RMG A;  3ID0 A;  2J1O A;  4P0W A;  2J5C A;  4LTZ A;  4RXA A;  3RYW A;  2Z4Y A;  3WEH A;  1HXC A;  4MC0 A;  3WCD A;  4DWB A;  5EAU A;  3KRA B;  4F62 A;  1UBY A;  3WEF A;  3WCF A;  5A0I A;  3PYA A;  2DH4 A;  4JZB A;  3ACW A;  3G4F A;  5JUZ F;  3WEK A;  1N24 A;  5B02 A;  2Z7H A;  3M00 A;  5A0J A;  3M9U A;  5JV1 F;  2F8Z F;  5EAS A;  4P0X A;  3KRA A;  4QPF A;  3SDR A;  1JFA A;  3ACX A;  1HX9 A;  3DYF A;  2J1P A;  1YYQ A;  4QXS F;  4FJQ A;  4N1Z F;  2ZCQ A;  5ILK A;  5ILY A;  4WK5 A;  3WE9 A;  4H5D F;  2ZCR A;  1YJ4 A;  1WL0 A;  3WCM A;  3ZOU A;  2F92 F;  3P8R A;  3SDT A;  4LA6 A;  5DZ2 A;  2Q9Y A;  4LZ3 A;  2F9K F;  2RAH A;  3WCA A;  4KWD A;  2ONH A;  4PVY F;  4KQS A;  5IMP A;  1YHK A;  3AQC B;  3LJI A;  4OKM A;  4E9Z A;  4PVX F;  3UCA A;  4LTV A;  1V4H A;  1YV5 A;  3Q30 A;  3WC9 A;  3BNY A;  3NPR A;  3P5P A;  3QKC A;  3WSA A;  3N5J F;  2F7M F;  3WCI A;  1EZF A;  4DEM F;  2E8U A;  2ZY1 A;  4H5E F;  3N45 F;  3PDE A;  2E8X A;  2OPN A;  5E8L A;  4MC3 A;  1VG4 A;  3ICZ A;  3VJA A;  4NKE A;  3N0G A;  3LGZ B;  3P8L A;  4KVD A;  2OPM A;  4E9U A;  4KFA A;  3KB9 A;  5IL3 A;  2ZCS A;  4KQ5 A;  4N9U A;  5A0K A;  1YQ7 A;  5IK6 A;  2Z7I A;  3VJB A;  4OMG A;  3IPI A;  1YYT A;  3V1V A;  3LDW A;  1YHL A;  5DGM F;  2AET A;  5IL8 A;  3VJE A;  4F6X A;  5ERO A;  5ILH A;  5B01 A;  5H9D A;  1DI1 A;  3VJC A;  3Q2Q A;  3LLW A;  4NKF A;  5JV2 F;  4NFI F;  4RXD A;  1ZW5 A;  3WSB A;  4LXW A;  4KVI A;  3WJK A;  5E8H A;  3RBM A;  2F89 F;  3VJ8 A;  3KRF B;  5HN8 A;  3LVS A;  3ICK A;  3WEG A;  1WMW A;  1N21 A;  3WCL A;  5B0K A;  3LEE A;  2E8W A;  3ICN A;  3IBA A;  4DZW A;  4EA2 A;  3KRF A;  5B0M A;  4KVY A;  4JXN A;  4LFE A;  5AEL A;  2F94 F;  1JFG A;  2F8C F;  4XQS F;  3KRC B;  3EZ3 A;  4RXE A;  5IVG A;  4KPD A;  5ER8 A;  1UBW A;  1RQI A;  3KRC A;  4RXC A;  4Q23 A;  4KVW A;  3KRP B;  3N3D A;  5ERN A;  1YYR A;  1HM7 A;  3WCB A;  5IK9 A;  2PS6 A;  3CKE A;  4JVJ F;  5IK0 A;  3SDQ A;  5DHI A;  3CP6 A;  2FOR A;  1HXA A;  3WCC A;  3TS7 A;  3KRP A;  4DWG A;  2E4O A;  5I1U A;  3B7L A;  3AE0 A;  3WJO A;  2Z4V A;  3OAC B;  2OA6 A;  4LA5 A;  2E95 A;  5AHU B;  4DI5 A;  2E93 A;  3LG5 A;  1FPS A;  3RYE A;  3N1W F;  1WL3 A;  5AYP A;  3Q2Z A;  3OAC A;  2PS4 A;  2EWG A;  5JA0 F;  2PS5 A;  2ZEV A;  4KKM A;  4NUA A;  4HD1 A;  4LLS A;  4LFG A;  2Z4Z A;  4KQU A;  5C05 A;  1VG7 A;  1V4I A;  3N0F A;  3G4D A;  2QIS A;  1WL2 A;  4KK2 A;  5KSX F;  1V4J A;  3OYR A;  5DJR F;  3W7F A;  3N1V F;  3ZMC A;  3EFQ A;  4OKZ A;  5AFX A;  5JV0 F;  3TFP A;  2E92 A;  1RTR A;  2ONG A;  4H5C F;  5DJV F;  5IMI A;  3ADZ A;  1DGP A;  4ZQ8 A;  1KIZ A;  1YHM A;  5DGS F;  4OGU A;  4F6V A;  3N3L F;  2E8T A;  5DHK A;  1WY0 A;  5DW7 A;  3CC9 A;  3V66 A;  5B0J A;  3WEJ A;  4RNQ A;  5IM1 A;  5ILJ A;  3TFV A;  3LGK A;  4LOB A; 
#chains in the Genus database with same CATH topology
 4MC8 A;  3LOM A;  3MZV A;  2E91 A;  2ZEU A;  3MAV A;  3N49 F;  2Q9Z A;  2VF6 A;  3PH7 A;  5E8K A;  4P0V A;  5B0I A;  4DHD A;  3NF2 A;  3DYH A;  3WCH A;  4GP2 A;  3S4J A;  4NG6 A;  3WCJ A;  1VG3 A;  5B03 A;  3QQV A;  5ILD A;  3TC1 A;  1WKZ A;  4NFJ F;  2AEL A;  4LZC A;  1VG2 A;  3ASX A;  5CG5 A;  4KPJ A;  5HNA A;  3ICM A;  2O1O A;  3ZL6 A;  3P5R A;  1N23 A;  3BNX A;  3WCE A;  5IKA A;  5IMN A;  3ACY A;  1UBV A;  2FTZ A;  1YYU A;  3N6K F;  2Q58 A;  5DGN F;  3TFN A;  4LPG F;  3DYG A;  4KUX A;  3N46 F;  4LUU A;  4JYX A;  4XQT F;  3VJD A;  3LZ9 A;  2OGD A;  1VG6 A;  2PS8 A;  4LFV F;  2Z50 A;  1HM4 A;  1N22 A;  4GA3 A;  3LK5 A;  3Q1O A;  1N20 A;  3VJ9 A;  1V4K A;  4DXJ A;  3PYB A;  1PS1 A;  4GP1 A;  4JZX A;  5B00 A;  3P41 A;  2E90 A;  3SDU A;  4JXY A;  3WEI A;  2H8O A;  3M0G A;  4K10 A;  2E94 A;  3M01 A;  2E8V A;  1KIY A;  5B0L A;  2PS7 A;  3KRO B;  4L2X F;  1UBX A;  3LMD A;  5ILI A;  4E1E A;  2P1C A;  1YYS A;  3APZ A;  4LLT A;  3SDV A;  1WL1 A;  3NRI A;  5IKH A;  3S9V A;  3KRO A;  2I19 A;  1V4E A;  4OMH A;  3N5H F;  2AZJ A;  4UMJ A;  5DJP F;  3SAE A;  4LPH F;  5ERM A;  4LZ0 A;  1HXG A;  2AZK A;  4RYP A;  1N1Z A;  2Z4W A;  2Z78 A;  2ZCO A;  5CG6 A;  5EAT A;  3ZMB A;  3KBK A;  5ILZ A;  2Q80 A;  4GAX A;  3AQ0 A;  3WJN A;  2Z52 A;  3LSN A;  4EA1 A;  4EA0 A;  3PKO A;  5DIQ F;  4LIX A;  5HN9 A;  2Z4X A;  3OAB B;  5IN8 A;  2AZL A;  3AQB B;  3NPK A;  3M02 A;  3EGT A;  1N1B A;  1RQJ A;  4XQR F;  5HN7 A;  2AEK A;  3WCG A;  4NFK F;  4FP4 A;  3ZCD A;  3V1X A;  3OAB A;  3RMG A;  3ID0 A;  2J1O A;  4P0W A;  2J5C A;  4LTZ A;  4RXA A;  3RYW A;  2Z4Y A;  3WEH A;  1HXC A;  4MC0 A;  3WCD A;  4DWB A;  5EAU A;  3KRA B;  4F62 A;  1UBY A;  3WEF A;  3WCF A;  5A0I A;  3PYA A;  2DH4 A;  4JZB A;  3ACW A;  3G4F A;  5JUZ F;  3WEK A;  1N24 A;  5B02 A;  2Z7H A;  3M00 A;  5A0J A;  3M9U A;  5JV1 F;  2F8Z F;  5EAS A;  4P0X A;  3KRA A;  4QPF A;  3SDR A;  1JFA A;  3ACX A;  1HX9 A;  3DYF A;  2J1P A;  1YYQ A;  4QXS F;  4FJQ A;  4N1Z F;  2ZCQ A;  5ILK A;  5ILY A;  4WK5 A;  3WE9 A;  4H5D F;  2ZCR A;  1YJ4 A;  1WL0 A;  3WCM A;  3ZOU A;  2F92 F;  3P8R A;  3SDT A;  4LA6 A;  5DZ2 A;  2Q9Y A;  4LZ3 A;  2F9K F;  2RAH A;  3WCA A;  4KWD A;  2ONH A;  4PVY F;  4KQS A;  5IMP A;  1YHK A;  3AQC B;  3LJI A;  4OKM A;  4E9Z A;  4PVX F;  3UCA A;  4LTV A;  1V4H A;  1YV5 A;  3Q30 A;  3WC9 A;  3BNY A;  3NPR A;  3P5P A;  3QKC A;  3WSA A;  3N5J F;  2F7M F;  3WCI A;  1EZF A;  4DEM F;  2E8U A;  2ZY1 A;  4H5E F;  3N45 F;  3PDE A;  2E8X A;  2OPN A;  5E8L A;  4MC3 A;  1VG4 A;  3ICZ A;  3VJA A;  4NKE A;  3N0G A;  3LGZ B;  3P8L A;  4KVD A;  2OPM A;  4E9U A;  4KFA A;  3KB9 A;  5IL3 A;  2ZCS A;  4KQ5 A;  4N9U A;  5A0K A;  1YQ7 A;  5IK6 A;  2Z7I A;  3VJB A;  4OMG A;  3IPI A;  1YYT A;  3V1V A;  3LDW A;  1YHL A;  5DGM F;  2AET A;  5IL8 A;  3VJE A;  4F6X A;  5ERO A;  5ILH A;  5B01 A;  5H9D A;  1DI1 A;  3VJC A;  3Q2Q A;  3LLW A;  4NKF A;  5JV2 F;  4NFI F;  4RXD A;  1ZW5 A;  3WSB A;  4LXW A;  4KVI A;  3WJK A;  5E8H A;  3RBM A;  2F89 F;  3VJ8 A;  3KRF B;  5HN8 A;  3LVS A;  3ICK A;  3WEG A;  1WMW A;  1N21 A;  3WCL A;  5B0K A;  3LEE A;  2E8W A;  3ICN A;  3IBA A;  4DZW A;  4EA2 A;  3KRF A;  5B0M A;  4KVY A;  4JXN A;  4LFE A;  5AEL A;  2F94 F;  1JFG A;  2F8C F;  4XQS F;  3KRC B;  3EZ3 A;  4RXE A;  5IVG A;  4KPD A;  5ER8 A;  1UBW A;  1RQI A;  3KRC A;  4RXC A;  4Q23 A;  4KVW A;  3KRP B;  3N3D A;  5ERN A;  1YYR A;  1HM7 A;  3WCB A;  5IK9 A;  2PS6 A;  3CKE A;  4JVJ F;  5IK0 A;  3SDQ A;  5DHI A;  3CP6 A;  2FOR A;  1HXA A;  3WCC A;  3TS7 A;  3KRP A;  4DWG A;  2E4O A;  5I1U A;  3B7L A;  3AE0 A;  3WJO A;  2Z4V A;  3OAC B;  2OA6 A;  4LA5 A;  2E95 A;  5AHU B;  4DI5 A;  2E93 A;  3LG5 A;  1FPS A;  3RYE A;  3N1W F;  1WL3 A;  5AYP A;  3Q2Z A;  3OAC A;  2PS4 A;  2EWG A;  5JA0 F;  2PS5 A;  2ZEV A;  4KKM A;  4NUA A;  4HD1 A;  4LLS A;  4LFG A;  2Z4Z A;  4KQU A;  5C05 A;  1VG7 A;  1V4I A;  3N0F A;  3G4D A;  2QIS A;  1WL2 A;  4KK2 A;  5KSX F;  1V4J A;  3OYR A;  5DJR F;  3W7F A;  3N1V F;  3ZMC A;  3EFQ A;  4OKZ A;  5AFX A;  5JV0 F;  3TFP A;  2E92 A;  1RTR A;  2ONG A;  4H5C F;  5DJV F;  5IMI A;  3ADZ A;  1DGP A;  4ZQ8 A;  1KIZ A;  1YHM A;  5DGS F;  4OGU A;  4F6V A;  3N3L F;  2E8T A;  5DHK A;  1WY0 A;  5DW7 A;  3CC9 A;  3V66 A;  5B0J A;  3WEJ A;  4RNQ A;  5IM1 A;  5ILJ A;  3TFV A;  3LGK A;  4LOB A; 
#chains in the Genus database with same CATH homology
 4MC8 A;  3LOM A;  3MZV A;  2E91 A;  2ZEU A;  3MAV A;  3N49 F;  2Q9Z A;  2VF6 A;  3PH7 A;  5E8K A;  4P0V A;  5B0I A;  4DHD A;  3NF2 A;  3DYH A;  3WCH A;  4GP2 A;  3S4J A;  4NG6 A;  3WCJ A;  1VG3 A;  5B03 A;  3QQV A;  5ILD A;  3TC1 A;  1WKZ A;  4NFJ F;  2AEL A;  4LZC A;  1VG2 A;  3ASX A;  5CG5 A;  4KPJ A;  5HNA A;  3ICM A;  2O1O A;  3ZL6 A;  3P5R A;  1N23 A;  3BNX A;  3WCE A;  5IKA A;  5IMN A;  3ACY A;  1UBV A;  2FTZ A;  1YYU A;  3N6K F;  2Q58 A;  5DGN F;  3TFN A;  4LPG F;  3DYG A;  4KUX A;  3N46 F;  4LUU A;  4JYX A;  4XQT F;  3VJD A;  3LZ9 A;  2OGD A;  1VG6 A;  2PS8 A;  4LFV F;  2Z50 A;  1HM4 A;  1N22 A;  4GA3 A;  3LK5 A;  3Q1O A;  1N20 A;  3VJ9 A;  1V4K A;  4DXJ A;  3PYB A;  1PS1 A;  4GP1 A;  4JZX A;  5B00 A;  3P41 A;  2E90 A;  3SDU A;  4JXY A;  3WEI A;  2H8O A;  3M0G A;  4K10 A;  2E94 A;  3M01 A;  2E8V A;  1KIY A;  5B0L A;  2PS7 A;  3KRO B;  4L2X F;  1UBX A;  3LMD A;  5ILI A;  4E1E A;  2P1C A;  1YYS A;  3APZ A;  4LLT A;  3SDV A;  1WL1 A;  3NRI A;  5IKH A;  3S9V A;  3KRO A;  2I19 A;  1V4E A;  4OMH A;  3N5H F;  2AZJ A;  4UMJ A;  5DJP F;  3SAE A;  4LPH F;  5ERM A;  4LZ0 A;  1HXG A;  2AZK A;  4RYP A;  1N1Z A;  2Z4W A;  2Z78 A;  2ZCO A;  5CG6 A;  5EAT A;  3ZMB A;  3KBK A;  5ILZ A;  2Q80 A;  4GAX A;  3AQ0 A;  3WJN A;  2Z52 A;  3LSN A;  4EA1 A;  4EA0 A;  3PKO A;  5DIQ F;  4LIX A;  5HN9 A;  2Z4X A;  3OAB B;  5IN8 A;  2AZL A;  3AQB B;  3NPK A;  3M02 A;  3EGT A;  1N1B A;  1RQJ A;  4XQR F;  5HN7 A;  2AEK A;  3WCG A;  4NFK F;  4FP4 A;  3ZCD A;  3V1X A;  3OAB A;  3RMG A;  3ID0 A;  2J1O A;  4P0W A;  2J5C A;  4LTZ A;  4RXA A;  3RYW A;  2Z4Y A;  3WEH A;  1HXC A;  4MC0 A;  3WCD A;  4DWB A;  5EAU A;  3KRA B;  4F62 A;  1UBY A;  3WEF A;  3WCF A;  5A0I A;  3PYA A;  2DH4 A;  4JZB A;  3ACW A;  3G4F A;  5JUZ F;  3WEK A;  1N24 A;  5B02 A;  2Z7H A;  3M00 A;  5A0J A;  3M9U A;  5JV1 F;  2F8Z F;  5EAS A;  4P0X A;  3KRA A;  4QPF A;  3SDR A;  1JFA A;  3ACX A;  1HX9 A;  3DYF A;  2J1P A;  1YYQ A;  4QXS F;  4FJQ A;  4N1Z F;  2ZCQ A;  5ILK A;  5ILY A;  4WK5 A;  3WE9 A;  4H5D F;  2ZCR A;  1YJ4 A;  1WL0 A;  3WCM A;  3ZOU A;  2F92 F;  3P8R A;  3SDT A;  4LA6 A;  5DZ2 A;  2Q9Y A;  4LZ3 A;  2F9K F;  2RAH A;  3WCA A;  4KWD A;  2ONH A;  4PVY F;  4KQS A;  5IMP A;  1YHK A;  3AQC B;  3LJI A;  4OKM A;  4E9Z A;  4PVX F;  3UCA A;  4LTV A;  1V4H A;  1YV5 A;  3Q30 A;  3WC9 A;  3BNY A;  3NPR A;  3P5P A;  3QKC A;  3WSA A;  3N5J F;  2F7M F;  3WCI A;  1EZF A;  4DEM F;  2E8U A;  2ZY1 A;  4H5E F;  3N45 F;  3PDE A;  2E8X A;  2OPN A;  5E8L A;  4MC3 A;  1VG4 A;  3ICZ A;  3VJA A;  4NKE A;  3N0G A;  3LGZ B;  3P8L A;  4KVD A;  2OPM A;  4E9U A;  4KFA A;  3KB9 A;  5IL3 A;  2ZCS A;  4KQ5 A;  4N9U A;  5A0K A;  1YQ7 A;  5IK6 A;  2Z7I A;  3VJB A;  4OMG A;  3IPI A;  1YYT A;  3V1V A;  3LDW A;  1YHL A;  5DGM F;  2AET A;  5IL8 A;  3VJE A;  4F6X A;  5ERO A;  5ILH A;  5B01 A;  5H9D A;  1DI1 A;  3VJC A;  3Q2Q A;  3LLW A;  4NKF A;  5JV2 F;  4NFI F;  4RXD A;  1ZW5 A;  3WSB A;  4LXW A;  4KVI A;  3WJK A;  5E8H A;  3RBM A;  2F89 F;  3VJ8 A;  3KRF B;  5HN8 A;  3LVS A;  3ICK A;  3WEG A;  1WMW A;  1N21 A;  3WCL A;  5B0K A;  3LEE A;  2E8W A;  3ICN A;  3IBA A;  4DZW A;  4EA2 A;  3KRF A;  5B0M A;  4KVY A;  4JXN A;  4LFE A;  5AEL A;  2F94 F;  1JFG A;  2F8C F;  4XQS F;  3KRC B;  3EZ3 A;  4RXE A;  5IVG A;  4KPD A;  5ER8 A;  1UBW A;  1RQI A;  3KRC A;  4RXC A;  4Q23 A;  4KVW A;  3KRP B;  3N3D A;  5ERN A;  1YYR A;  1HM7 A;  3WCB A;  5IK9 A;  2PS6 A;  3CKE A;  4JVJ F;  5IK0 A;  3SDQ A;  5DHI A;  3CP6 A;  2FOR A;  1HXA A;  3WCC A;  3TS7 A;  3KRP A;  4DWG A;  2E4O A;  5I1U A;  3B7L A;  3AE0 A;  3WJO A;  2Z4V A;  3OAC B;  2OA6 A;  4LA5 A;  2E95 A;  5AHU B;  4DI5 A;  2E93 A;  3LG5 A;  1FPS A;  3RYE A;  3N1W F;  1WL3 A;  5AYP A;  3Q2Z A;  3OAC A;  2PS4 A;  2EWG A;  5JA0 F;  2PS5 A;  2ZEV A;  4KKM A;  4NUA A;  4HD1 A;  4LLS A;  4LFG A;  2Z4Z A;  4KQU A;  5C05 A;  1VG7 A;  1V4I A;  3N0F A;  3G4D A;  2QIS A;  1WL2 A;  4KK2 A;  5KSX F;  1V4J A;  3OYR A;  5DJR F;  3W7F A;  3N1V F;  3ZMC A;  3EFQ A;  4OKZ A;  5AFX A;  5JV0 F;  3TFP A;  2E92 A;  1RTR A;  2ONG A;  4H5C F;  5DJV F;  5IMI A;  3ADZ A;  1DGP A;  4ZQ8 A;  1KIZ A;  1YHM A;  5DGS F;  4OGU A;  4F6V A;  3N3L F;  2E8T A;  5DHK A;  1WY0 A;  5DW7 A;  3CC9 A;  3V66 A;  5B0J A;  3WEJ A;  4RNQ A;  5IM1 A;  5ILJ A;  3TFV A;  3LGK A;  4LOB A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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