5AELA

T. brucei farnesyl diphosphate synthase complexed with bisphosphonate bph-597
Total Genus 148
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
148
sequence length
367
structure length
357
Chain Sequence
MPMQMFMQVYDEIQMFLLEELELKFDMDPNRVRYLRKMMDTTCLGGKYNRGLTVIDVAESLLSDGARRKRVLHDACVCGWMIEFLQAHYLVEDDIMDNSVTRRGKPCWYRHPDVTVQCAINDGLLLKSWTHMMAMHFFADRPFLQDLLCRFNRVDYTTAVGQLYDVTSMFDSNKLDPDVSQPTTTDFAEFTLSNYKRIVKYKTAYYTYLLPLVMGLIVSEALPTVDMGVTEELAMLMGEYFQVQDDVMDCFTPPERLGKVGTDIQDAKCSWLAVTFLAKASSAQVAEFKANYGSGDSEKVATVRRLYEEADLQGDYVAYEAAVAEQVKELIEKLRLCSPGFAASVETLWGKTYKRQK
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Inhibition of Trypanosoma Brucei Cell Growth by Lipophilic Bisphosphonates: An in Vitro and in Vivo Investigation.
pubmed doi rcsb
molecule tags Transferase
source organism Trypanosoma brucei
molecule keywords FARNESYL PYROPHOSPHATE SYNTHASE
total genus 148
structure length 357
sequence length 367
chains with identical sequence B
ec nomenclature ec 2.5.1.10: (2E,6E)-farnesyl diphosphate synthase.
pdb deposition date 2014-12-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00348 polyprenyl_synt Polyprenyl synthetase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.600.10 Mainly Alpha Orthogonal Bundle Farnesyl Diphosphate Synthase Farnesyl Diphosphate Synthase 5aelA00
1RQJA 4LA6A 1YYUA 5B00A 1V4IA 3ADZA 3ID0A 1WY0A 2F7MF 2E90A 2F89F 5DIQF 5DW7A 3VJDA 3KRAB 1WMWA 1YYRA 1UBXA 5HN9A 3OACA 1YYSA 4UMJA 4JZXA 2E8UA 5IKAA 3V1VA 2F9KF 5JV0F 1YYQA 1V4JA 4LLSA 3LGZB 4LPGF 2Z52A 3N3DA 2E8VA 3CP6A 3WCEA 3V1XA 1DGPA 3Q2QA 5JV1F 1V4EA 1DI1A 1EZFA 4LTVA 2E92A 3SDTA 4OMHA 3PH7A 3SDRA 5A0IA 2Q80A 5IL3A 5ILIA 3KRFA 1ZW5A 2PS4A 5DJPF 4GP1A 4DZWA 2J1OA 1N1ZA 4LZ3A 5I1UA 5AELA 4JXNA 4EA2A 3EZ3A 5IK6A 2ZCRA 5IK9A 3WCCA 5E8HA 2FTZA 3WCGA 3WC9A 3WEKA 3VJ9A 5IL8A 4HD1A 5EROA 3N0GA 1JFAA 3WCMA 5ILHA 4LA5A 3M02A 2Z78A 5IKHA 1YHMA 3QKCA 1YHKA 2Z4WA 3ZMBA 2Z50A 2E8WA 4N1ZF 3LG5A 2AEKA 3ACXA 1KIZA 4JZBA 5E8LA 5IN8A 4KPJA 4LOBA 3N0FA 2F8ZF 4E1EA 3N46F 4RXCA 4LFEA 2Z7HA 4DXJA 4LZCA 2EWGA 4KKMA 2ONHA 3TFPA 5JUZF 4DHDA 3WCLA 3LVSA 4KUXA 3NPKA 3VJAA 3ZOUA 2Q58A 1WL1A 3AQ0A 3MZVA 2ZCOA 1UBVA 3TFNA 2VF6A 3NPRA 4LXWA 3KRPA 3AQBB 4RXAA 3PKOA 3DYFA 1WL0A 5IMIA 4FJQA 5ERMA 5IVGA 1YYTA 4NKFA 4KPDA 3LDWA 1VG6A 1HXGA 2OA6A 1YQ7A 2I19A 2ONGA 3LGKA 1JFGA 3N5JF 3DYHA 2ZEUA 1HX9A 4OMGA 3TFVA 3PYBA 2OPMA 3VJCA 2P1CA 4GA3A 4LLTA 2J1PA 3KRFB 3SDUA 4KWDA 3RYWA 3LEEA 3EGTA 5IM1A 5EASA 4KVYA 3CKEA 3OYRA 1WL3A 3P8LA 4WK5A 5A0JA 3OABA 4QPFA 4LUUA 5DGMF 4P0VA 3QQVA 3S4JA 3KBKA 4F6XA 4Q23A 2E91A 4H5DF 4NFIF 2Z4XA 4DEMF 1N20A 4EA0A 1UBWA 3RMGA 3ZCDA 3RBMA 2OGDA 3S9VA 4OKMA 3WCFA 3M9UA 4XQSF 3WEIA 4LIXA 4F62A 2ZCSA 3ZMCA 4OKZA 3CC9A 4OGUA 3LOMA 5DJRF 4LFVF 3WCDA 1VG3A 5AFXA 5E8KA 5AYPA 3N49F 3N6KF 2E93A 3WCAA 4P0WA 4FP4A 2AETA 4MC0A 1N24A 5JA0F 5IMNA 3M00A 3KROB 4F6VA 2Q9YA 4H5CF 3KB9A 4MC8A 1PS1A 5KSXF 4QXSF 3IBAA 1KIYA 3VJBA 3WJNA 1HXCA 1UBYA 5IMPA 5DJVF 3PDEA 4KK2A 1HM7A 1N22A 5C05A 3MAVA 5EAUA 2AELA 1V4HA 4XQRF 3OACB 4NKEA 5B0JA 3WEFA 5ILZA 3WEHA 5B02A 4RNQA 1N23A 2F92F 2E8TA 3ASXA 2PS7A 3ICZA 2QISA 3OABB 4KVWA 5HN8A 3APZA 3G4FA 4KVIA 5AHUB 2E94A 3NRIA 3SAEA 5HN7A 3W7FA 4RYPA 2E4OA 4NFKF 2F8CF 4GP2A 3WCHA 4L2XF 3P5PA 2AZKA 3AQCB 1HXAA 3EFQA 3N1WF 3BNYA 3P41A 2AZJA 5DGNF 4RXEA 3LK5A 3LZ9A 5JV2F 3KRCA 4ZQ8A 3WCJA 3TS7A 3LMDA 1VG7A 2RAHA 5B03A 1YJ4A 4PVXF 5B0IA 3ZL6A 2J5CA 4KQ5A 3LSNA 3ICKA 3ICNA 5ILJA 2Z4VA 1VG4A 3WJKA 3NF2A 3TC1A 4JVJF 5CG5A 3WEJA 5IK0A 4KFAA 5H9DA 3WSAA 2Z4ZA 4KQUA 3N45F 4PVYF 4DWBA 1WL2A 3DYGA 4KQSA 2Z7IA 2ZEVA 3M01A 3VJ8A 2FORA 3Q1OA 5ERNA 4NG6A 2E95A 3ICMA 3ACYA 5CG6A 3RYEA 3ACWA 3N3LF 4JYXA 2OPNA 3UCAA 5B01A 3IPIA 5HNAA 3N5HF 2PS6A 5B0KA 5ILDA 4RXDA 3KRAA 3M0GA 4NFJF 2ZCQA 1VG2A 2PS5A 2F94F 4LPHF 4H5EF 4N9UA 3Q30A 4E9UA 4LFGA 5A0KA 3KRPB 4JXYA 1N1BA 3LJIA 1FPSA 5EATA 2E8XA 3SDVA 3WE9A 1N21A 3G4DA 2DH4A 5DGSF 3P5RA 4DI5A 1RQIA 4E9ZA 4DWGA 5ILKA 1WKZA 3P8RA 1HM4A 2H8OA 1YHLA 3WEGA 3B7LA 3Q2ZA 3PYAA 2Q9ZA 5DHKA 3WJOA 2O1OA 2Z4YA 5B0LA 3LLWA 4K10A 1YV5A 2ZY1A 3KRCB 4GAXA 4KVDA 3WCBA 5ILYA 1V4KA 3N1VF 5ER8A 5DZ2A 1RTRA 2AZLA 5DHIA 4NUAA 4LZ0A 4LTZA 3VJEA 2PS8A 4EA1A 3AE0A 3V66A 3SDQA 3BNXA 3WCIA 4P0XA 5B0MA 3KROA 4MC3A 4XQTF 3WSBA
chains in the Genus database with same CATH superfamily
1RQJA 4LA6A 1YYUA 5B00A 1V4IA 3ADZA 3ID0A 1WY0A 2F7MF 2E90A 2F89F 5DIQF 5DW7A 3VJDA 3KRAB 1WMWA 1YYRA 1UBXA 5HN9A 3OACA 1YYSA 4UMJA 4JZXA 2E8UA 5IKAA 3V1VA 2F9KF 5JV0F 1YYQA 1V4JA 4LLSA 3LGZB 4LPGF 2Z52A 3N3DA 2E8VA 3CP6A 3WCEA 3V1XA 1DGPA 3Q2QA 5JV1F 1V4EA 1DI1A 1EZFA 4LTVA 2E92A 3SDTA 4OMHA 3PH7A 3SDRA 5A0IA 2Q80A 5IL3A 5ILIA 3KRFA 1ZW5A 2PS4A 5DJPF 4GP1A 4DZWA 2J1OA 1N1ZA 4LZ3A 5I1UA 5AELA 4JXNA 4EA2A 3EZ3A 5IK6A 2ZCRA 5IK9A 3WCCA 5E8HA 2FTZA 3WCGA 3WC9A 3WEKA 3VJ9A 5IL8A 4HD1A 5EROA 3N0GA 1JFAA 3WCMA 5ILHA 4LA5A 3M02A 2Z78A 5IKHA 1YHMA 3QKCA 1YHKA 2Z4WA 3ZMBA 2Z50A 2E8WA 4N1ZF 3LG5A 2AEKA 3ACXA 1KIZA 4JZBA 5E8LA 5IN8A 4KPJA 4LOBA 3N0FA 2F8ZF 4E1EA 3N46F 4RXCA 4LFEA 2Z7HA 4DXJA 4LZCA 2EWGA 4KKMA 2ONHA 3TFPA 5JUZF 4DHDA 3WCLA 3LVSA 4KUXA 3NPKA 3VJAA 3ZOUA 2Q58A 1WL1A 3AQ0A 3MZVA 2ZCOA 1UBVA 3TFNA 2VF6A 3NPRA 4LXWA 3KRPA 3AQBB 4RXAA 3PKOA 3DYFA 1WL0A 5IMIA 4FJQA 5ERMA 5IVGA 1YYTA 4NKFA 4KPDA 3LDWA 1VG6A 1HXGA 2OA6A 1YQ7A 2I19A 2ONGA 3LGKA 1JFGA 3N5JF 3DYHA 2ZEUA 1HX9A 4OMGA 3TFVA 3PYBA 2OPMA 3VJCA 2P1CA 4GA3A 4LLTA 2J1PA 3KRFB 3SDUA 4KWDA 3RYWA 3LEEA 3EGTA 5IM1A 5EASA 4KVYA 3CKEA 3OYRA 1WL3A 3P8LA 4WK5A 5A0JA 3OABA 4QPFA 4LUUA 5DGMF 4P0VA 3QQVA 3S4JA 3KBKA 4F6XA 4Q23A 2E91A 4H5DF 4NFIF 2Z4XA 4DEMF 1N20A 4EA0A 1UBWA 3RMGA 3ZCDA 3RBMA 2OGDA 3S9VA 4OKMA 3WCFA 3M9UA 4XQSF 3WEIA 4LIXA 4F62A 2ZCSA 3ZMCA 4OKZA 3CC9A 4OGUA 3LOMA 5DJRF 4LFVF 3WCDA 1VG3A 5AFXA 5E8KA 5AYPA 3N49F 3N6KF 2E93A 3WCAA 4P0WA 4FP4A 2AETA 4MC0A 1N24A 5JA0F 5IMNA 3M00A 3KROB 4F6VA 2Q9YA 4H5CF 3KB9A 4MC8A 1PS1A 5KSXF 4QXSF 3IBAA 1KIYA 3VJBA 3WJNA 1HXCA 1UBYA 5IMPA 5DJVF 3PDEA 4KK2A 1HM7A 1N22A 5C05A 3MAVA 5EAUA 2AELA 1V4HA 4XQRF 3OACB 4NKEA 5B0JA 3WEFA 5ILZA 3WEHA 5B02A 4RNQA 1N23A 2F92F 2E8TA 3ASXA 2PS7A 3ICZA 2QISA 3OABB 4KVWA 5HN8A 3APZA 3G4FA 4KVIA 5AHUB 2E94A 3NRIA 3SAEA 5HN7A 3W7FA 4RYPA 2E4OA 4NFKF 2F8CF 4GP2A 3WCHA 4L2XF 3P5PA 2AZKA 3AQCB 1HXAA 3EFQA 3N1WF 3BNYA 3P41A 2AZJA 5DGNF 4RXEA 3LK5A 3LZ9A 5JV2F 3KRCA 4ZQ8A 3WCJA 3TS7A 3LMDA 1VG7A 2RAHA 5B03A 1YJ4A 4PVXF 5B0IA 3ZL6A 2J5CA 4KQ5A 3LSNA 3ICKA 3ICNA 5ILJA 2Z4VA 1VG4A 3WJKA 3NF2A 3TC1A 4JVJF 5CG5A 3WEJA 5IK0A 4KFAA 5H9DA 3WSAA 2Z4ZA 4KQUA 3N45F 4PVYF 4DWBA 1WL2A 3DYGA 4KQSA 2Z7IA 2ZEVA 3M01A 3VJ8A 2FORA 3Q1OA 5ERNA 4NG6A 2E95A 3ICMA 3ACYA 5CG6A 3RYEA 3ACWA 3N3LF 4JYXA 2OPNA 3UCAA 5B01A 3IPIA 5HNAA 3N5HF 2PS6A 5B0KA 5ILDA 4RXDA 3KRAA 3M0GA 4NFJF 2ZCQA 1VG2A 2PS5A 2F94F 4LPHF 4H5EF 4N9UA 3Q30A 4E9UA 4LFGA 5A0KA 3KRPB 4JXYA 1N1BA 3LJIA 1FPSA 5EATA 2E8XA 3SDVA 3WE9A 1N21A 3G4DA 2DH4A 5DGSF 3P5RA 4DI5A 1RQIA 4E9ZA 4DWGA 5ILKA 1WKZA 3P8RA 1HM4A 2H8OA 1YHLA 3WEGA 3B7LA 3Q2ZA 3PYAA 2Q9ZA 5DHKA 3WJOA 2O1OA 2Z4YA 5B0LA 3LLWA 4K10A 1YV5A 2ZY1A 3KRCB 4GAXA 4KVDA 3WCBA 5ILYA 1V4KA 3N1VF 5ER8A 5DZ2A 1RTRA 2AZLA 5DHIA 4NUAA 4LZ0A 4LTZA 3VJEA 2PS8A 4EA1A 3AE0A 3V66A 3SDQA 3BNXA 3WCIA 4P0XA 5B0MA 3KROA 4MC3A 4XQTF 3WSBA
chains in the Genus database with same CATH topology
1RQJA 4LA6A 1YYUA 5B00A 1V4IA 3ADZA 3ID0A 1WY0A 2F7MF 2E90A 2F89F 5DIQF 5DW7A 3VJDA 3KRAB 1WMWA 1YYRA 1UBXA 5HN9A 3OACA 1YYSA 4UMJA 4JZXA 2E8UA 5IKAA 3V1VA 2F9KF 5JV0F 1YYQA 1V4JA 4LLSA 3LGZB 4LPGF 2Z52A 3N3DA 2E8VA 3CP6A 3WCEA 3V1XA 1DGPA 3Q2QA 5JV1F 1V4EA 1DI1A 1EZFA 4LTVA 2E92A 3SDTA 4OMHA 3PH7A 3SDRA 5A0IA 2Q80A 5IL3A 5ILIA 3KRFA 1ZW5A 2PS4A 5DJPF 4GP1A 4DZWA 2J1OA 1N1ZA 4LZ3A 5I1UA 5AELA 4JXNA 4EA2A 3EZ3A 5IK6A 2ZCRA 5IK9A 3WCCA 5E8HA 2FTZA 3WCGA 3WC9A 3WEKA 3VJ9A 5IL8A 4HD1A 5EROA 3N0GA 1JFAA 3WCMA 5ILHA 4LA5A 3M02A 2Z78A 5IKHA 1YHMA 3QKCA 1YHKA 2Z4WA 3ZMBA 2Z50A 2E8WA 4N1ZF 3LG5A 2AEKA 3ACXA 1KIZA 4JZBA 5E8LA 5IN8A 4KPJA 4LOBA 3N0FA 2F8ZF 4E1EA 3N46F 4RXCA 4LFEA 2Z7HA 4DXJA 4LZCA 2EWGA 4KKMA 2ONHA 3TFPA 5JUZF 4DHDA 3WCLA 3LVSA 4KUXA 3NPKA 3VJAA 3ZOUA 2Q58A 1WL1A 3AQ0A 3MZVA 2ZCOA 1UBVA 3TFNA 2VF6A 3NPRA 4LXWA 3KRPA 3AQBB 4RXAA 3PKOA 3DYFA 1WL0A 5IMIA 4FJQA 5ERMA 5IVGA 1YYTA 4NKFA 4KPDA 3LDWA 1VG6A 1HXGA 2OA6A 1YQ7A 2I19A 2ONGA 3LGKA 1JFGA 3N5JF 3DYHA 2ZEUA 1HX9A 4OMGA 3TFVA 3PYBA 2OPMA 3VJCA 2P1CA 4GA3A 4LLTA 2J1PA 3KRFB 3SDUA 4KWDA 3RYWA 3LEEA 3EGTA 5IM1A 5EASA 4KVYA 3CKEA 3OYRA 1WL3A 3P8LA 4WK5A 5A0JA 3OABA 4QPFA 4LUUA 5DGMF 4P0VA 3QQVA 3S4JA 3KBKA 4F6XA 4Q23A 2E91A 4H5DF 4NFIF 2Z4XA 4DEMF 1N20A 4EA0A 1UBWA 3RMGA 3ZCDA 3RBMA 2OGDA 3S9VA 4OKMA 3WCFA 3M9UA 4XQSF 3WEIA 4LIXA 4F62A 2ZCSA 3ZMCA 4OKZA 3CC9A 4OGUA 3LOMA 5DJRF 4LFVF 3WCDA 1VG3A 5AFXA 5E8KA 5AYPA 3N49F 3N6KF 2E93A 3WCAA 4P0WA 4FP4A 2AETA 4MC0A 1N24A 5JA0F 5IMNA 3M00A 3KROB 4F6VA 2Q9YA 4H5CF 3KB9A 4MC8A 1PS1A 5KSXF 4QXSF 3IBAA 1KIYA 3VJBA 3WJNA 1HXCA 1UBYA 5IMPA 5DJVF 3PDEA 4KK2A 1HM7A 1N22A 5C05A 3MAVA 5EAUA 2AELA 1V4HA 4XQRF 3OACB 4NKEA 5B0JA 3WEFA 5ILZA 3WEHA 5B02A 4RNQA 1N23A 2F92F 2E8TA 3ASXA 2PS7A 3ICZA 2QISA 3OABB 4KVWA 5HN8A 3APZA 3G4FA 4KVIA 5AHUB 2E94A 3NRIA 3SAEA 5HN7A 3W7FA 4RYPA 2E4OA 4NFKF 2F8CF 4GP2A 3WCHA 4L2XF 3P5PA 2AZKA 3AQCB 1HXAA 3EFQA 3N1WF 3BNYA 3P41A 2AZJA 5DGNF 4RXEA 3LK5A 3LZ9A 5JV2F 3KRCA 4ZQ8A 3WCJA 3TS7A 3LMDA 1VG7A 2RAHA 5B03A 1YJ4A 4PVXF 5B0IA 3ZL6A 2J5CA 4KQ5A 3LSNA 3ICKA 3ICNA 5ILJA 2Z4VA 1VG4A 3WJKA 3NF2A 3TC1A 4JVJF 5CG5A 3WEJA 5IK0A 4KFAA 5H9DA 3WSAA 2Z4ZA 4KQUA 3N45F 4PVYF 4DWBA 1WL2A 3DYGA 4KQSA 2Z7IA 2ZEVA 3M01A 3VJ8A 2FORA 3Q1OA 5ERNA 4NG6A 2E95A 3ICMA 3ACYA 5CG6A 3RYEA 3ACWA 3N3LF 4JYXA 2OPNA 3UCAA 5B01A 3IPIA 5HNAA 3N5HF 2PS6A 5B0KA 5ILDA 4RXDA 3KRAA 3M0GA 4NFJF 2ZCQA 1VG2A 2PS5A 2F94F 4LPHF 4H5EF 4N9UA 3Q30A 4E9UA 4LFGA 5A0KA 3KRPB 4JXYA 1N1BA 3LJIA 1FPSA 5EATA 2E8XA 3SDVA 3WE9A 1N21A 3G4DA 2DH4A 5DGSF 3P5RA 4DI5A 1RQIA 4E9ZA 4DWGA 5ILKA 1WKZA 3P8RA 1HM4A 2H8OA 1YHLA 3WEGA 3B7LA 3Q2ZA 3PYAA 2Q9ZA 5DHKA 3WJOA 2O1OA 2Z4YA 5B0LA 3LLWA 4K10A 1YV5A 2ZY1A 3KRCB 4GAXA 4KVDA 3WCBA 5ILYA 1V4KA 3N1VF 5ER8A 5DZ2A 1RTRA 2AZLA 5DHIA 4NUAA 4LZ0A 4LTZA 3VJEA 2PS8A 4EA1A 3AE0A 3V66A 3SDQA 3BNXA 3WCIA 4P0XA 5B0MA 3KROA 4MC3A 4XQTF 3WSBA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1RQJ A;  4LA6 A;  1YYU A;  5B00 A;  1V4I A;  3ADZ A;  3ID0 A;  1WY0 A;  2F7M F;  2E90 A;  2F89 F;  5DIQ F;  5DW7 A;  3VJD A;  3KRA B;  1WMW A;  1YYR A;  1UBX A;  5HN9 A;  3OAC A;  1YYS A;  4UMJ A;  4JZX A;  2E8U A;  5IKA A;  3V1V A;  2F9K F;  5JV0 F;  1YYQ A;  1V4J A;  4LLS A;  3LGZ B;  4LPG F;  2Z52 A;  3N3D A;  2E8V A;  3CP6 A;  3WCE A;  3V1X A;  1DGP A;  3Q2Q A;  5JV1 F;  1V4E A;  1DI1 A;  1EZF A;  4LTV A;  2E92 A;  3SDT A;  4OMH A;  3PH7 A;  3SDR A;  5A0I A;  2Q80 A;  5IL3 A;  5ILI A;  3KRF A;  1ZW5 A;  2PS4 A;  5DJP F;  4GP1 A;  4DZW A;  2J1O A;  1N1Z A;  4LZ3 A;  5I1U A;  5AEL A;  4JXN A;  4EA2 A;  3EZ3 A;  5IK6 A;  2ZCR A;  5IK9 A;  3WCC A;  5E8H A;  2FTZ A;  3WCG A;  3WC9 A;  3WEK A;  3VJ9 A;  5IL8 A;  4HD1 A;  5ERO A;  3N0G A;  1JFA A;  3WCM A;  5ILH A;  4LA5 A;  3M02 A;  2Z78 A;  5IKH A;  1YHM A;  3QKC A;  1YHK A;  2Z4W A;  3ZMB A;  2Z50 A;  2E8W A;  4N1Z F;  3LG5 A;  2AEK A;  3ACX A;  1KIZ A;  4JZB A;  5E8L A;  5IN8 A;  4KPJ A;  4LOB A;  3N0F A;  2F8Z F;  4E1E A;  3N46 F;  4RXC A;  4LFE A;  2Z7H A;  4DXJ A;  4LZC A;  2EWG A;  4KKM A;  2ONH A;  3TFP A;  5JUZ F;  4DHD A;  3WCL A;  3LVS A;  4KUX A;  3NPK A;  3VJA A;  3ZOU A;  2Q58 A;  1WL1 A;  3AQ0 A;  3MZV A;  2ZCO A;  1UBV A;  3TFN A;  2VF6 A;  3NPR A;  4LXW A;  3KRP A;  3AQB B;  4RXA A;  3PKO A;  3DYF A;  1WL0 A;  5IMI A;  4FJQ A;  5ERM A;  5IVG A;  1YYT A;  4NKF A;  4KPD A;  3LDW A;  1VG6 A;  1HXG A;  2OA6 A;  1YQ7 A;  2I19 A;  2ONG A;  3LGK A;  1JFG A;  3N5J F;  3DYH A;  2ZEU A;  1HX9 A;  4OMG A;  3TFV A;  3PYB A;  2OPM A;  3VJC A;  2P1C A;  4GA3 A;  4LLT A;  2J1P A;  3KRF B;  3SDU A;  4KWD A;  3RYW A;  3LEE A;  3EGT A;  5IM1 A;  5EAS A;  4KVY A;  3CKE A;  3OYR A;  1WL3 A;  3P8L A;  4WK5 A;  5A0J A;  3OAB A;  4QPF A;  4LUU A;  5DGM F;  4P0V A;  3QQV A;  3S4J A;  3KBK A;  4F6X A;  4Q23 A;  2E91 A;  4H5D F;  4NFI F;  2Z4X A;  4DEM F;  1N20 A;  4EA0 A;  1UBW A;  3RMG A;  3ZCD A;  3RBM A;  2OGD A;  3S9V A;  4OKM A;  3WCF A;  3M9U A;  4XQS F;  3WEI A;  4LIX A;  4F62 A;  2ZCS A;  3ZMC A;  4OKZ A;  3CC9 A;  4OGU A;  3LOM A;  5DJR F;  4LFV F;  3WCD A;  1VG3 A;  5AFX A;  5E8K A;  5AYP A;  3N49 F;  3N6K F;  2E93 A;  3WCA A;  4P0W A;  4FP4 A;  2AET A;  4MC0 A;  1N24 A;  5JA0 F;  5IMN A;  3M00 A;  3KRO B;  4F6V A;  2Q9Y A;  4H5C F;  3KB9 A;  4MC8 A;  1PS1 A;  5KSX F;  4QXS F;  3IBA A;  1KIY A;  3VJB A;  3WJN A;  1HXC A;  1UBY A;  5IMP A;  5DJV F;  3PDE A;  4KK2 A;  1HM7 A;  1N22 A;  5C05 A;  3MAV A;  5EAU A;  2AEL A;  1V4H A;  4XQR F;  3OAC B;  4NKE A;  5B0J A;  3WEF A;  5ILZ A;  3WEH A;  5B02 A;  4RNQ A;  1N23 A;  2F92 F;  2E8T A;  3ASX A;  2PS7 A;  3ICZ A;  2QIS A;  3OAB B;  4KVW A;  5HN8 A;  3APZ A;  3G4F A;  4KVI A;  5AHU B;  2E94 A;  3NRI A;  3SAE A;  5HN7 A;  3W7F A;  4RYP A;  2E4O A;  4NFK F;  2F8C F;  4GP2 A;  3WCH A;  4L2X F;  3P5P A;  2AZK A;  3AQC B;  1HXA A;  3EFQ A;  3N1W F;  3BNY A;  3P41 A;  2AZJ A;  5DGN F;  4RXE A;  3LK5 A;  3LZ9 A;  5JV2 F;  3KRC A;  4ZQ8 A;  3WCJ A;  3TS7 A;  3LMD A;  1VG7 A;  2RAH A;  5B03 A;  1YJ4 A;  4PVX F;  5B0I A;  3ZL6 A;  2J5C A;  4KQ5 A;  3LSN A;  3ICK A;  3ICN A;  5ILJ A;  2Z4V A;  1VG4 A;  3WJK A;  3NF2 A;  3TC1 A;  4JVJ F;  5CG5 A;  3WEJ A;  5IK0 A;  4KFA A;  5H9D A;  3WSA A;  2Z4Z A;  4KQU A;  3N45 F;  4PVY F;  4DWB A;  1WL2 A;  3DYG A;  4KQS A;  2Z7I A;  2ZEV A;  3M01 A;  3VJ8 A;  2FOR A;  3Q1O A;  5ERN A;  4NG6 A;  2E95 A;  3ICM A;  3ACY A;  5CG6 A;  3RYE A;  3ACW A;  3N3L F;  4JYX A;  2OPN A;  3UCA A;  5B01 A;  3IPI A;  5HNA A;  3N5H F;  2PS6 A;  5B0K A;  5ILD A;  4RXD A;  3KRA A;  3M0G A;  4NFJ F;  2ZCQ A;  1VG2 A;  2PS5 A;  2F94 F;  4LPH F;  4H5E F;  4N9U A;  3Q30 A;  4E9U A;  4LFG A;  5A0K A;  3KRP B;  4JXY A;  1N1B A;  3LJI A;  1FPS A;  5EAT A;  2E8X A;  3SDV A;  3WE9 A;  1N21 A;  3G4D A;  2DH4 A;  5DGS F;  3P5R A;  4DI5 A;  1RQI A;  4E9Z A;  4DWG A;  5ILK A;  1WKZ A;  3P8R A;  1HM4 A;  2H8O A;  1YHL A;  3WEG A;  3B7L A;  3Q2Z A;  3PYA A;  2Q9Z A;  5DHK A;  3WJO A;  2O1O A;  2Z4Y A;  5B0L A;  3LLW A;  4K10 A;  1YV5 A;  2ZY1 A;  3KRC B;  4GAX A;  4KVD A;  3WCB A;  5ILY A;  1V4K A;  3N1V F;  5ER8 A;  5DZ2 A;  1RTR A;  2AZL A;  5DHI A;  4NUA A;  4LZ0 A;  4LTZ A;  3VJE A;  2PS8 A;  4EA1 A;  3AE0 A;  3V66 A;  3SDQ A;  3BNX A;  3WCI A;  4P0X A;  5B0M A;  3KRO A;  4MC3 A;  4XQT F;  3WSB A; 
#chains in the Genus database with same CATH topology
 1RQJ A;  4LA6 A;  1YYU A;  5B00 A;  1V4I A;  3ADZ A;  3ID0 A;  1WY0 A;  2F7M F;  2E90 A;  2F89 F;  5DIQ F;  5DW7 A;  3VJD A;  3KRA B;  1WMW A;  1YYR A;  1UBX A;  5HN9 A;  3OAC A;  1YYS A;  4UMJ A;  4JZX A;  2E8U A;  5IKA A;  3V1V A;  2F9K F;  5JV0 F;  1YYQ A;  1V4J A;  4LLS A;  3LGZ B;  4LPG F;  2Z52 A;  3N3D A;  2E8V A;  3CP6 A;  3WCE A;  3V1X A;  1DGP A;  3Q2Q A;  5JV1 F;  1V4E A;  1DI1 A;  1EZF A;  4LTV A;  2E92 A;  3SDT A;  4OMH A;  3PH7 A;  3SDR A;  5A0I A;  2Q80 A;  5IL3 A;  5ILI A;  3KRF A;  1ZW5 A;  2PS4 A;  5DJP F;  4GP1 A;  4DZW A;  2J1O A;  1N1Z A;  4LZ3 A;  5I1U A;  5AEL A;  4JXN A;  4EA2 A;  3EZ3 A;  5IK6 A;  2ZCR A;  5IK9 A;  3WCC A;  5E8H A;  2FTZ A;  3WCG A;  3WC9 A;  3WEK A;  3VJ9 A;  5IL8 A;  4HD1 A;  5ERO A;  3N0G A;  1JFA A;  3WCM A;  5ILH A;  4LA5 A;  3M02 A;  2Z78 A;  5IKH A;  1YHM A;  3QKC A;  1YHK A;  2Z4W A;  3ZMB A;  2Z50 A;  2E8W A;  4N1Z F;  3LG5 A;  2AEK A;  3ACX A;  1KIZ A;  4JZB A;  5E8L A;  5IN8 A;  4KPJ A;  4LOB A;  3N0F A;  2F8Z F;  4E1E A;  3N46 F;  4RXC A;  4LFE A;  2Z7H A;  4DXJ A;  4LZC A;  2EWG A;  4KKM A;  2ONH A;  3TFP A;  5JUZ F;  4DHD A;  3WCL A;  3LVS A;  4KUX A;  3NPK A;  3VJA A;  3ZOU A;  2Q58 A;  1WL1 A;  3AQ0 A;  3MZV A;  2ZCO A;  1UBV A;  3TFN A;  2VF6 A;  3NPR A;  4LXW A;  3KRP A;  3AQB B;  4RXA A;  3PKO A;  3DYF A;  1WL0 A;  5IMI A;  4FJQ A;  5ERM A;  5IVG A;  1YYT A;  4NKF A;  4KPD A;  3LDW A;  1VG6 A;  1HXG A;  2OA6 A;  1YQ7 A;  2I19 A;  2ONG A;  3LGK A;  1JFG A;  3N5J F;  3DYH A;  2ZEU A;  1HX9 A;  4OMG A;  3TFV A;  3PYB A;  2OPM A;  3VJC A;  2P1C A;  4GA3 A;  4LLT A;  2J1P A;  3KRF B;  3SDU A;  4KWD A;  3RYW A;  3LEE A;  3EGT A;  5IM1 A;  5EAS A;  4KVY A;  3CKE A;  3OYR A;  1WL3 A;  3P8L A;  4WK5 A;  5A0J A;  3OAB A;  4QPF A;  4LUU A;  5DGM F;  4P0V A;  3QQV A;  3S4J A;  3KBK A;  4F6X A;  4Q23 A;  2E91 A;  4H5D F;  4NFI F;  2Z4X A;  4DEM F;  1N20 A;  4EA0 A;  1UBW A;  3RMG A;  3ZCD A;  3RBM A;  2OGD A;  3S9V A;  4OKM A;  3WCF A;  3M9U A;  4XQS F;  3WEI A;  4LIX A;  4F62 A;  2ZCS A;  3ZMC A;  4OKZ A;  3CC9 A;  4OGU A;  3LOM A;  5DJR F;  4LFV F;  3WCD A;  1VG3 A;  5AFX A;  5E8K A;  5AYP A;  3N49 F;  3N6K F;  2E93 A;  3WCA A;  4P0W A;  4FP4 A;  2AET A;  4MC0 A;  1N24 A;  5JA0 F;  5IMN A;  3M00 A;  3KRO B;  4F6V A;  2Q9Y A;  4H5C F;  3KB9 A;  4MC8 A;  1PS1 A;  5KSX F;  4QXS F;  3IBA A;  1KIY A;  3VJB A;  3WJN A;  1HXC A;  1UBY A;  5IMP A;  5DJV F;  3PDE A;  4KK2 A;  1HM7 A;  1N22 A;  5C05 A;  3MAV A;  5EAU A;  2AEL A;  1V4H A;  4XQR F;  3OAC B;  4NKE A;  5B0J A;  3WEF A;  5ILZ A;  3WEH A;  5B02 A;  4RNQ A;  1N23 A;  2F92 F;  2E8T A;  3ASX A;  2PS7 A;  3ICZ A;  2QIS A;  3OAB B;  4KVW A;  5HN8 A;  3APZ A;  3G4F A;  4KVI A;  5AHU B;  2E94 A;  3NRI A;  3SAE A;  5HN7 A;  3W7F A;  4RYP A;  2E4O A;  4NFK F;  2F8C F;  4GP2 A;  3WCH A;  4L2X F;  3P5P A;  2AZK A;  3AQC B;  1HXA A;  3EFQ A;  3N1W F;  3BNY A;  3P41 A;  2AZJ A;  5DGN F;  4RXE A;  3LK5 A;  3LZ9 A;  5JV2 F;  3KRC A;  4ZQ8 A;  3WCJ A;  3TS7 A;  3LMD A;  1VG7 A;  2RAH A;  5B03 A;  1YJ4 A;  4PVX F;  5B0I A;  3ZL6 A;  2J5C A;  4KQ5 A;  3LSN A;  3ICK A;  3ICN A;  5ILJ A;  2Z4V A;  1VG4 A;  3WJK A;  3NF2 A;  3TC1 A;  4JVJ F;  5CG5 A;  3WEJ A;  5IK0 A;  4KFA A;  5H9D A;  3WSA A;  2Z4Z A;  4KQU A;  3N45 F;  4PVY F;  4DWB A;  1WL2 A;  3DYG A;  4KQS A;  2Z7I A;  2ZEV A;  3M01 A;  3VJ8 A;  2FOR A;  3Q1O A;  5ERN A;  4NG6 A;  2E95 A;  3ICM A;  3ACY A;  5CG6 A;  3RYE A;  3ACW A;  3N3L F;  4JYX A;  2OPN A;  3UCA A;  5B01 A;  3IPI A;  5HNA A;  3N5H F;  2PS6 A;  5B0K A;  5ILD A;  4RXD A;  3KRA A;  3M0G A;  4NFJ F;  2ZCQ A;  1VG2 A;  2PS5 A;  2F94 F;  4LPH F;  4H5E F;  4N9U A;  3Q30 A;  4E9U A;  4LFG A;  5A0K A;  3KRP B;  4JXY A;  1N1B A;  3LJI A;  1FPS A;  5EAT A;  2E8X A;  3SDV A;  3WE9 A;  1N21 A;  3G4D A;  2DH4 A;  5DGS F;  3P5R A;  4DI5 A;  1RQI A;  4E9Z A;  4DWG A;  5ILK A;  1WKZ A;  3P8R A;  1HM4 A;  2H8O A;  1YHL A;  3WEG A;  3B7L A;  3Q2Z A;  3PYA A;  2Q9Z A;  5DHK A;  3WJO A;  2O1O A;  2Z4Y A;  5B0L A;  3LLW A;  4K10 A;  1YV5 A;  2ZY1 A;  3KRC B;  4GAX A;  4KVD A;  3WCB A;  5ILY A;  1V4K A;  3N1V F;  5ER8 A;  5DZ2 A;  1RTR A;  2AZL A;  5DHI A;  4NUA A;  4LZ0 A;  4LTZ A;  3VJE A;  2PS8 A;  4EA1 A;  3AE0 A;  3V66 A;  3SDQ A;  3BNX A;  3WCI A;  4P0X A;  5B0M A;  3KRO A;  4MC3 A;  4XQT F;  3WSB A; 
#chains in the Genus database with same CATH homology
 1RQJ A;  4LA6 A;  1YYU A;  5B00 A;  1V4I A;  3ADZ A;  3ID0 A;  1WY0 A;  2F7M F;  2E90 A;  2F89 F;  5DIQ F;  5DW7 A;  3VJD A;  3KRA B;  1WMW A;  1YYR A;  1UBX A;  5HN9 A;  3OAC A;  1YYS A;  4UMJ A;  4JZX A;  2E8U A;  5IKA A;  3V1V A;  2F9K F;  5JV0 F;  1YYQ A;  1V4J A;  4LLS A;  3LGZ B;  4LPG F;  2Z52 A;  3N3D A;  2E8V A;  3CP6 A;  3WCE A;  3V1X A;  1DGP A;  3Q2Q A;  5JV1 F;  1V4E A;  1DI1 A;  1EZF A;  4LTV A;  2E92 A;  3SDT A;  4OMH A;  3PH7 A;  3SDR A;  5A0I A;  2Q80 A;  5IL3 A;  5ILI A;  3KRF A;  1ZW5 A;  2PS4 A;  5DJP F;  4GP1 A;  4DZW A;  2J1O A;  1N1Z A;  4LZ3 A;  5I1U A;  5AEL A;  4JXN A;  4EA2 A;  3EZ3 A;  5IK6 A;  2ZCR A;  5IK9 A;  3WCC A;  5E8H A;  2FTZ A;  3WCG A;  3WC9 A;  3WEK A;  3VJ9 A;  5IL8 A;  4HD1 A;  5ERO A;  3N0G A;  1JFA A;  3WCM A;  5ILH A;  4LA5 A;  3M02 A;  2Z78 A;  5IKH A;  1YHM A;  3QKC A;  1YHK A;  2Z4W A;  3ZMB A;  2Z50 A;  2E8W A;  4N1Z F;  3LG5 A;  2AEK A;  3ACX A;  1KIZ A;  4JZB A;  5E8L A;  5IN8 A;  4KPJ A;  4LOB A;  3N0F A;  2F8Z F;  4E1E A;  3N46 F;  4RXC A;  4LFE A;  2Z7H A;  4DXJ A;  4LZC A;  2EWG A;  4KKM A;  2ONH A;  3TFP A;  5JUZ F;  4DHD A;  3WCL A;  3LVS A;  4KUX A;  3NPK A;  3VJA A;  3ZOU A;  2Q58 A;  1WL1 A;  3AQ0 A;  3MZV A;  2ZCO A;  1UBV A;  3TFN A;  2VF6 A;  3NPR A;  4LXW A;  3KRP A;  3AQB B;  4RXA A;  3PKO A;  3DYF A;  1WL0 A;  5IMI A;  4FJQ A;  5ERM A;  5IVG A;  1YYT A;  4NKF A;  4KPD A;  3LDW A;  1VG6 A;  1HXG A;  2OA6 A;  1YQ7 A;  2I19 A;  2ONG A;  3LGK A;  1JFG A;  3N5J F;  3DYH A;  2ZEU A;  1HX9 A;  4OMG A;  3TFV A;  3PYB A;  2OPM A;  3VJC A;  2P1C A;  4GA3 A;  4LLT A;  2J1P A;  3KRF B;  3SDU A;  4KWD A;  3RYW A;  3LEE A;  3EGT A;  5IM1 A;  5EAS A;  4KVY A;  3CKE A;  3OYR A;  1WL3 A;  3P8L A;  4WK5 A;  5A0J A;  3OAB A;  4QPF A;  4LUU A;  5DGM F;  4P0V A;  3QQV A;  3S4J A;  3KBK A;  4F6X A;  4Q23 A;  2E91 A;  4H5D F;  4NFI F;  2Z4X A;  4DEM F;  1N20 A;  4EA0 A;  1UBW A;  3RMG A;  3ZCD A;  3RBM A;  2OGD A;  3S9V A;  4OKM A;  3WCF A;  3M9U A;  4XQS F;  3WEI A;  4LIX A;  4F62 A;  2ZCS A;  3ZMC A;  4OKZ A;  3CC9 A;  4OGU A;  3LOM A;  5DJR F;  4LFV F;  3WCD A;  1VG3 A;  5AFX A;  5E8K A;  5AYP A;  3N49 F;  3N6K F;  2E93 A;  3WCA A;  4P0W A;  4FP4 A;  2AET A;  4MC0 A;  1N24 A;  5JA0 F;  5IMN A;  3M00 A;  3KRO B;  4F6V A;  2Q9Y A;  4H5C F;  3KB9 A;  4MC8 A;  1PS1 A;  5KSX F;  4QXS F;  3IBA A;  1KIY A;  3VJB A;  3WJN A;  1HXC A;  1UBY A;  5IMP A;  5DJV F;  3PDE A;  4KK2 A;  1HM7 A;  1N22 A;  5C05 A;  3MAV A;  5EAU A;  2AEL A;  1V4H A;  4XQR F;  3OAC B;  4NKE A;  5B0J A;  3WEF A;  5ILZ A;  3WEH A;  5B02 A;  4RNQ A;  1N23 A;  2F92 F;  2E8T A;  3ASX A;  2PS7 A;  3ICZ A;  2QIS A;  3OAB B;  4KVW A;  5HN8 A;  3APZ A;  3G4F A;  4KVI A;  5AHU B;  2E94 A;  3NRI A;  3SAE A;  5HN7 A;  3W7F A;  4RYP A;  2E4O A;  4NFK F;  2F8C F;  4GP2 A;  3WCH A;  4L2X F;  3P5P A;  2AZK A;  3AQC B;  1HXA A;  3EFQ A;  3N1W F;  3BNY A;  3P41 A;  2AZJ A;  5DGN F;  4RXE A;  3LK5 A;  3LZ9 A;  5JV2 F;  3KRC A;  4ZQ8 A;  3WCJ A;  3TS7 A;  3LMD A;  1VG7 A;  2RAH A;  5B03 A;  1YJ4 A;  4PVX F;  5B0I A;  3ZL6 A;  2J5C A;  4KQ5 A;  3LSN A;  3ICK A;  3ICN A;  5ILJ A;  2Z4V A;  1VG4 A;  3WJK A;  3NF2 A;  3TC1 A;  4JVJ F;  5CG5 A;  3WEJ A;  5IK0 A;  4KFA A;  5H9D A;  3WSA A;  2Z4Z A;  4KQU A;  3N45 F;  4PVY F;  4DWB A;  1WL2 A;  3DYG A;  4KQS A;  2Z7I A;  2ZEV A;  3M01 A;  3VJ8 A;  2FOR A;  3Q1O A;  5ERN A;  4NG6 A;  2E95 A;  3ICM A;  3ACY A;  5CG6 A;  3RYE A;  3ACW A;  3N3L F;  4JYX A;  2OPN A;  3UCA A;  5B01 A;  3IPI A;  5HNA A;  3N5H F;  2PS6 A;  5B0K A;  5ILD A;  4RXD A;  3KRA A;  3M0G A;  4NFJ F;  2ZCQ A;  1VG2 A;  2PS5 A;  2F94 F;  4LPH F;  4H5E F;  4N9U A;  3Q30 A;  4E9U A;  4LFG A;  5A0K A;  3KRP B;  4JXY A;  1N1B A;  3LJI A;  1FPS A;  5EAT A;  2E8X A;  3SDV A;  3WE9 A;  1N21 A;  3G4D A;  2DH4 A;  5DGS F;  3P5R A;  4DI5 A;  1RQI A;  4E9Z A;  4DWG A;  5ILK A;  1WKZ A;  3P8R A;  1HM4 A;  2H8O A;  1YHL A;  3WEG A;  3B7L A;  3Q2Z A;  3PYA A;  2Q9Z A;  5DHK A;  3WJO A;  2O1O A;  2Z4Y A;  5B0L A;  3LLW A;  4K10 A;  1YV5 A;  2ZY1 A;  3KRC B;  4GAX A;  4KVD A;  3WCB A;  5ILY A;  1V4K A;  3N1V F;  5ER8 A;  5DZ2 A;  1RTR A;  2AZL A;  5DHI A;  4NUA A;  4LZ0 A;  4LTZ A;  3VJE A;  2PS8 A;  4EA1 A;  3AE0 A;  3V66 A;  3SDQ A;  3BNX A;  3WCI A;  4P0X A;  5B0M A;  3KRO A;  4MC3 A;  4XQT F;  3WSB A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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