5AHUB

T. brucei farnesyl diphosphate synthase complexed with bisphosphonate bph-1326
Total Genus 115
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
115
sequence length
294
structure length
294
Chain Sequence
DGARRKRVLHDACVCGWMIEFLQAHYLVEDDIMDNSVTRRGKPCWYRHPDVTVQCAINDGLLLKSWTHMMAMHFFADRPFLQDLLCRFNRVDYTTAVGQLYDVTSMFDSNKLDPDVSQPTTTDFAEFTLSNYKRIVKYKTAYYTYLLPLVMGLIVSEALPTVDMGVTEELAMLMGEYFQVQDDVMDCFTPPERLGKVGTDIQDAKCSWLAVTFLAKASSAQVAEFKANYGSGDSEKVATVRRLYEEADLQGDYVAYEAAVAEQVKELIEKLRLCSPGFAASVETLWGKTYKRQK
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Inhibition of Trypanosoma Brucei Cell Growth by Lipophilic Bisphosphonates: An in Vitro and in Vivo Investigation.
pubmed doi rcsb
molecule tags Transferase
source organism Trypanosoma brucei
molecule keywords FARNESYL PYROPHOSPHATE SYNTHASE, PUTATIVE
total genus 115
structure length 294
sequence length 294
chains with identical sequence D
ec nomenclature
pdb deposition date 2015-02-09
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.600.10 Mainly Alpha Orthogonal Bundle Farnesyl Diphosphate Synthase Farnesyl Diphosphate Synthase 5ahuB00
5DJVF 1WY0A 4KQSA 3TFPA 2Z4WA 3ZOUA 3ZL6A 3ICNA 1HXCA 3KRFA 3KRCB 5IVGA 3PYBA 2E8UA 4OMHA 4RXDA 4LPHF 5IMNA 5B0KA 1EZFA 1VG7A 3DYFA 4E1EA 4L2XF 1N24A 5B0JA 4Q23A 3ZCDA 2F9KF 2H8OA 4LIXA 4OKZA 1HM4A 1UBYA 5DGNF 2Q58A 3KROA 1JFGA 4K10A 5AYPA 2OA6A 5IK6A 3P5RA 3WCHA 2E93A 3KRPA 3BNXA 4DXJA 3VJ9A 1YYSA 2O1OA 4LXWA 5B0LA 4DWBA 4KVDA 3SDRA 3WE9A 5HN9A 2OPNA 4LTZA 3V1VA 3N46F 1YYRA 3OABA 2ONGA 5ILYA 2PS6A 4KVYA 4LA5A 4UMJA 2PS4A 4NKEA 3KRAA 1YQ7A 5IK9A 5B00A 4RNQA 5AELA 4JVJF 3ACXA 4NFJF 3ZMCA 4KPJA 3KBKA 5JA0F 5AHUB 2Z7HA 3BNYA 1RQJA 1PS1A 2J1OA 3CC9A 3WCLA 3OYRA 1ZW5A 3SDUA 5IKAA 5B0MA 1UBWA 4MC0A 3N5HF 4FP4A 4LLSA 4LPGF 4WK5A 5C05A 1UBXA 1VG3A 4P0XA 5DW7A 2E95A 2E8VA 3PKOA 4NKFA 2E8WA 1V4HA 3ID0A 3WSBA 4E9UA 2Q80A 3LVSA 3TC1A 3M0GA 3LJIA 2Z78A 3OACB 3P41A 5A0KA 3LEEA 5DHKA 5IL8A 5ERMA 4HD1A 1WKZA 5ER8A 4NUAA 4PVXF 5ILIA 1N21A 1KIZA 2PS5A 1V4EA 4LOBA 5AFXA 4NFKF 1V4KA 4H5DF 4LFEA 5ILKA 2P1CA 2F8CF 3Q2QA 2E4OA 3M9UA 5B03A 5IN8A 3AE0A 4EA1A 3SDQA 4DWGA 4EA0A 2Z4XA 3V66A 4F62A 5IK0A 3EZ3A 5JV2F 1KIYA 3N3LF 4XQTF 3NPKA 5HN7A 4LZCA 4LFVF 3Q1OA 4XQSF 4JXNA 3SDVA 4E9ZA 3WEKA 3RMGA 4MC8A 2F92F 1V4JA 3WCIA 1YYQA 4QXSF 3WEHA 3VJDA 3EGTA 5DJRF 1JFAA 1YYTA 3VJAA 2AEKA 5DGMF 4NG6A 4EA2A 3WEJA 2F8ZF 4JXYA 4PVYF 4QPFA 3N5JF 3WJKA 3TFVA 3EFQA 1YJ4A 3S9VA 3Q2ZA 5ILDA 3LDWA 4JYXA 3ICKA 2Z4YA 3IBAA 3QKCA 5E8HA 5KSXF 1V4IA 1UBVA 4OGUA 2QISA 2ONHA 3TS7A 2AETA 4OKMA 3N6KF 3WCMA 3KRFB 2J1PA 2Q9YA 1RTRA 3N1WF 3N0GA 4DHDA 3NF2A 5DZ2A 3ASXA 3VJ8A 3WEFA 3LZ9A 3CKEA 4LTVA 3WCBA 5B01A 3VJCA 1N20A 3WCGA 5IMPA 2ZCQA 3N3DA 5A0JA 3UCAA 3KROB 5EAUA 5JV0F 3KRCA 1WMWA 3WEGA 3ICZA 3AQCB 3AQ0A 1N23A 5ILHA 4KUXA 3KRPB 3N0FA 1YHMA 3W7FA 5DIQF 3LOMA 3WSAA 5B0IA 3M01A 1WL1A 4KVIA 4DEMF 3QQVA 5CG6A 4F6XA 2F7MF 2I19A 3MZVA 3OABB 3WEIA 4GP2A 3ADZA 3Q30A 3KRAB 4XQRF 1HX9A 5HN8A 3WJNA 1VG4A 3N45F 3WCJA 3PYAA 1WL0A 3B7LA 2AELA 3RYEA 2E92A 3DYGA 3MAVA 4KVWA 3LK5A 3M00A 3LMDA 3N49F 5IKHA 4MC3A 1HM7A 5E8KA 3WCAA 3M02A 3WC9A 1YYUA 3RBMA 1WL3A 3KB9A 2ZEUA 3P8RA 4DZWA 3ACWA 5IMIA 5JV1F 4KK2A 2PS8A 2E94A 2OPMA 3PH7A 1FPSA 2ZY1A 1VG2A 2F89F 3N1VF 4GA3A 1VG6A 3LGKA 5DJPF 3APZA 2E8TA 4FJQA 4LZ0A 5IL3A 5B02A 5JUZF 3P8LA 4RXAA 3LGZB 3TFNA 4KQ5A 3WCFA 1DGPA 5CG5A 4RYPA 2Z4VA 3NRIA 5DGSF 4KPDA 5DHIA 2PS7A 1N1ZA 3P5PA 2E90A 2AZJA 5IM1A 2ZCSA 4NFIF 4F6VA 3PDEA 1YV5A 3ACYA 3WCDA 3G4FA 4N1ZF 3SAEA 3OACA 2E8XA 3WJOA 4KWDA 1DI1A 3VJEA 3WCCA 3G4DA 2ZCOA 4LUUA 2VF6A 2Z7IA 2F94F 4H5CF 4DI5A 2Z4ZA 3CP6A 5HNAA 4KQUA 3IPIA 3LG5A 4LA6A 3WCEA 3SDTA 3VJBA 4H5EF 2ZEVA 2E91A 2FORA 1RQIA 4P0WA 5EATA 4GP1A 4OMGA 5EROA 4JZBA 1YHKA 1HXAA 5ILZA 2Q9ZA 3LLWA 3RYWA 3ZMBA 2Z50A 2AZKA 2OGDA 3LSNA 3NPRA 1N1BA 1WL2A 4ZQ8A 4LZ3A 2EWGA 3DYHA 4KKMA 2J5CA 5I1UA 4LFGA 4JZXA 4RXEA 3V1XA 5H9DA 5ILJA 5ERNA 1YHLA 4N9UA 1N22A 2ZCRA 3AQBB 2FTZA 2RAHA 1HXGA 2AZLA 2Z52A 4LLTA 2DH4A 5EASA 5A0IA 5E8LA 4GAXA 3S4JA 4RXCA 3ICMA 4P0VA 4KFAA
chains in the Genus database with same CATH superfamily
5DJVF 1WY0A 4KQSA 3TFPA 2Z4WA 3ZOUA 3ZL6A 3ICNA 1HXCA 3KRFA 3KRCB 5IVGA 3PYBA 2E8UA 4OMHA 4RXDA 4LPHF 5IMNA 5B0KA 1EZFA 1VG7A 3DYFA 4E1EA 4L2XF 1N24A 5B0JA 4Q23A 3ZCDA 2F9KF 2H8OA 4LIXA 4OKZA 1HM4A 1UBYA 5DGNF 2Q58A 3KROA 1JFGA 4K10A 5AYPA 2OA6A 5IK6A 3P5RA 3WCHA 2E93A 3KRPA 3BNXA 4DXJA 3VJ9A 1YYSA 2O1OA 4LXWA 5B0LA 4DWBA 4KVDA 3SDRA 3WE9A 5HN9A 2OPNA 4LTZA 3V1VA 3N46F 1YYRA 3OABA 2ONGA 5ILYA 2PS6A 4KVYA 4LA5A 4UMJA 2PS4A 4NKEA 3KRAA 1YQ7A 5IK9A 5B00A 4RNQA 5AELA 4JVJF 3ACXA 4NFJF 3ZMCA 4KPJA 3KBKA 5JA0F 5AHUB 2Z7HA 3BNYA 1RQJA 1PS1A 2J1OA 3CC9A 3WCLA 3OYRA 1ZW5A 3SDUA 5IKAA 5B0MA 1UBWA 4MC0A 3N5HF 4FP4A 4LLSA 4LPGF 4WK5A 5C05A 1UBXA 1VG3A 4P0XA 5DW7A 2E95A 2E8VA 3PKOA 4NKFA 2E8WA 1V4HA 3ID0A 3WSBA 4E9UA 2Q80A 3LVSA 3TC1A 3M0GA 3LJIA 2Z78A 3OACB 3P41A 5A0KA 3LEEA 5DHKA 5IL8A 5ERMA 4HD1A 1WKZA 5ER8A 4NUAA 4PVXF 5ILIA 1N21A 1KIZA 2PS5A 1V4EA 4LOBA 5AFXA 4NFKF 1V4KA 4H5DF 4LFEA 5ILKA 2P1CA 2F8CF 3Q2QA 2E4OA 3M9UA 5B03A 5IN8A 3AE0A 4EA1A 3SDQA 4DWGA 4EA0A 2Z4XA 3V66A 4F62A 5IK0A 3EZ3A 5JV2F 1KIYA 3N3LF 4XQTF 3NPKA 5HN7A 4LZCA 4LFVF 3Q1OA 4XQSF 4JXNA 3SDVA 4E9ZA 3WEKA 3RMGA 4MC8A 2F92F 1V4JA 3WCIA 1YYQA 4QXSF 3WEHA 3VJDA 3EGTA 5DJRF 1JFAA 1YYTA 3VJAA 2AEKA 5DGMF 4NG6A 4EA2A 3WEJA 2F8ZF 4JXYA 4PVYF 4QPFA 3N5JF 3WJKA 3TFVA 3EFQA 1YJ4A 3S9VA 3Q2ZA 5ILDA 3LDWA 4JYXA 3ICKA 2Z4YA 3IBAA 3QKCA 5E8HA 5KSXF 1V4IA 1UBVA 4OGUA 2QISA 2ONHA 3TS7A 2AETA 4OKMA 3N6KF 3WCMA 3KRFB 2J1PA 2Q9YA 1RTRA 3N1WF 3N0GA 4DHDA 3NF2A 5DZ2A 3ASXA 3VJ8A 3WEFA 3LZ9A 3CKEA 4LTVA 3WCBA 5B01A 3VJCA 1N20A 3WCGA 5IMPA 2ZCQA 3N3DA 5A0JA 3UCAA 3KROB 5EAUA 5JV0F 3KRCA 1WMWA 3WEGA 3ICZA 3AQCB 3AQ0A 1N23A 5ILHA 4KUXA 3KRPB 3N0FA 1YHMA 3W7FA 5DIQF 3LOMA 3WSAA 5B0IA 3M01A 1WL1A 4KVIA 4DEMF 3QQVA 5CG6A 4F6XA 2F7MF 2I19A 3MZVA 3OABB 3WEIA 4GP2A 3ADZA 3Q30A 3KRAB 4XQRF 1HX9A 5HN8A 3WJNA 1VG4A 3N45F 3WCJA 3PYAA 1WL0A 3B7LA 2AELA 3RYEA 2E92A 3DYGA 3MAVA 4KVWA 3LK5A 3M00A 3LMDA 3N49F 5IKHA 4MC3A 1HM7A 5E8KA 3WCAA 3M02A 3WC9A 1YYUA 3RBMA 1WL3A 3KB9A 2ZEUA 3P8RA 4DZWA 3ACWA 5IMIA 5JV1F 4KK2A 2PS8A 2E94A 2OPMA 3PH7A 1FPSA 2ZY1A 1VG2A 2F89F 3N1VF 4GA3A 1VG6A 3LGKA 5DJPF 3APZA 2E8TA 4FJQA 4LZ0A 5IL3A 5B02A 5JUZF 3P8LA 4RXAA 3LGZB 3TFNA 4KQ5A 3WCFA 1DGPA 5CG5A 4RYPA 2Z4VA 3NRIA 5DGSF 4KPDA 5DHIA 2PS7A 1N1ZA 3P5PA 2E90A 2AZJA 5IM1A 2ZCSA 4NFIF 4F6VA 3PDEA 1YV5A 3ACYA 3WCDA 3G4FA 4N1ZF 3SAEA 3OACA 2E8XA 3WJOA 4KWDA 1DI1A 3VJEA 3WCCA 3G4DA 2ZCOA 4LUUA 2VF6A 2Z7IA 2F94F 4H5CF 4DI5A 2Z4ZA 3CP6A 5HNAA 4KQUA 3IPIA 3LG5A 4LA6A 3WCEA 3SDTA 3VJBA 4H5EF 2ZEVA 2E91A 2FORA 1RQIA 4P0WA 5EATA 4GP1A 4OMGA 5EROA 4JZBA 1YHKA 1HXAA 5ILZA 2Q9ZA 3LLWA 3RYWA 3ZMBA 2Z50A 2AZKA 2OGDA 3LSNA 3NPRA 1N1BA 1WL2A 4ZQ8A 4LZ3A 2EWGA 3DYHA 4KKMA 2J5CA 5I1UA 4LFGA 4JZXA 4RXEA 3V1XA 5H9DA 5ILJA 5ERNA 1YHLA 4N9UA 1N22A 2ZCRA 3AQBB 2FTZA 2RAHA 1HXGA 2AZLA 2Z52A 4LLTA 2DH4A 5EASA 5A0IA 5E8LA 4GAXA 3S4JA 4RXCA 3ICMA 4P0VA 4KFAA
chains in the Genus database with same CATH topology
5DJVF 1WY0A 4KQSA 3TFPA 2Z4WA 3ZOUA 3ZL6A 3ICNA 1HXCA 3KRFA 3KRCB 5IVGA 3PYBA 2E8UA 4OMHA 4RXDA 4LPHF 5IMNA 5B0KA 1EZFA 1VG7A 3DYFA 4E1EA 4L2XF 1N24A 5B0JA 4Q23A 3ZCDA 2F9KF 2H8OA 4LIXA 4OKZA 1HM4A 1UBYA 5DGNF 2Q58A 3KROA 1JFGA 4K10A 5AYPA 2OA6A 5IK6A 3P5RA 3WCHA 2E93A 3KRPA 3BNXA 4DXJA 3VJ9A 1YYSA 2O1OA 4LXWA 5B0LA 4DWBA 4KVDA 3SDRA 3WE9A 5HN9A 2OPNA 4LTZA 3V1VA 3N46F 1YYRA 3OABA 2ONGA 5ILYA 2PS6A 4KVYA 4LA5A 4UMJA 2PS4A 4NKEA 3KRAA 1YQ7A 5IK9A 5B00A 4RNQA 5AELA 4JVJF 3ACXA 4NFJF 3ZMCA 4KPJA 3KBKA 5JA0F 5AHUB 2Z7HA 3BNYA 1RQJA 1PS1A 2J1OA 3CC9A 3WCLA 3OYRA 1ZW5A 3SDUA 5IKAA 5B0MA 1UBWA 4MC0A 3N5HF 4FP4A 4LLSA 4LPGF 4WK5A 5C05A 1UBXA 1VG3A 4P0XA 5DW7A 2E95A 2E8VA 3PKOA 4NKFA 2E8WA 1V4HA 3ID0A 3WSBA 4E9UA 2Q80A 3LVSA 3TC1A 3M0GA 3LJIA 2Z78A 3OACB 3P41A 5A0KA 3LEEA 5DHKA 5IL8A 5ERMA 4HD1A 1WKZA 5ER8A 4NUAA 4PVXF 5ILIA 1N21A 1KIZA 2PS5A 1V4EA 4LOBA 5AFXA 4NFKF 1V4KA 4H5DF 4LFEA 5ILKA 2P1CA 2F8CF 3Q2QA 2E4OA 3M9UA 5B03A 5IN8A 3AE0A 4EA1A 3SDQA 4DWGA 4EA0A 2Z4XA 3V66A 4F62A 5IK0A 3EZ3A 5JV2F 1KIYA 3N3LF 4XQTF 3NPKA 5HN7A 4LZCA 4LFVF 3Q1OA 4XQSF 4JXNA 3SDVA 4E9ZA 3WEKA 3RMGA 4MC8A 2F92F 1V4JA 3WCIA 1YYQA 4QXSF 3WEHA 3VJDA 3EGTA 5DJRF 1JFAA 1YYTA 3VJAA 2AEKA 5DGMF 4NG6A 4EA2A 3WEJA 2F8ZF 4JXYA 4PVYF 4QPFA 3N5JF 3WJKA 3TFVA 3EFQA 1YJ4A 3S9VA 3Q2ZA 5ILDA 3LDWA 4JYXA 3ICKA 2Z4YA 3IBAA 3QKCA 5E8HA 5KSXF 1V4IA 1UBVA 4OGUA 2QISA 2ONHA 3TS7A 2AETA 4OKMA 3N6KF 3WCMA 3KRFB 2J1PA 2Q9YA 1RTRA 3N1WF 3N0GA 4DHDA 3NF2A 5DZ2A 3ASXA 3VJ8A 3WEFA 3LZ9A 3CKEA 4LTVA 3WCBA 5B01A 3VJCA 1N20A 3WCGA 5IMPA 2ZCQA 3N3DA 5A0JA 3UCAA 3KROB 5EAUA 5JV0F 3KRCA 1WMWA 3WEGA 3ICZA 3AQCB 3AQ0A 1N23A 5ILHA 4KUXA 3KRPB 3N0FA 1YHMA 3W7FA 5DIQF 3LOMA 3WSAA 5B0IA 3M01A 1WL1A 4KVIA 4DEMF 3QQVA 5CG6A 4F6XA 2F7MF 2I19A 3MZVA 3OABB 3WEIA 4GP2A 3ADZA 3Q30A 3KRAB 4XQRF 1HX9A 5HN8A 3WJNA 1VG4A 3N45F 3WCJA 3PYAA 1WL0A 3B7LA 2AELA 3RYEA 2E92A 3DYGA 3MAVA 4KVWA 3LK5A 3M00A 3LMDA 3N49F 5IKHA 4MC3A 1HM7A 5E8KA 3WCAA 3M02A 3WC9A 1YYUA 3RBMA 1WL3A 3KB9A 2ZEUA 3P8RA 4DZWA 3ACWA 5IMIA 5JV1F 4KK2A 2PS8A 2E94A 2OPMA 3PH7A 1FPSA 2ZY1A 1VG2A 2F89F 3N1VF 4GA3A 1VG6A 3LGKA 5DJPF 3APZA 2E8TA 4FJQA 4LZ0A 5IL3A 5B02A 5JUZF 3P8LA 4RXAA 3LGZB 3TFNA 4KQ5A 3WCFA 1DGPA 5CG5A 4RYPA 2Z4VA 3NRIA 5DGSF 4KPDA 5DHIA 2PS7A 1N1ZA 3P5PA 2E90A 2AZJA 5IM1A 2ZCSA 4NFIF 4F6VA 3PDEA 1YV5A 3ACYA 3WCDA 3G4FA 4N1ZF 3SAEA 3OACA 2E8XA 3WJOA 4KWDA 1DI1A 3VJEA 3WCCA 3G4DA 2ZCOA 4LUUA 2VF6A 2Z7IA 2F94F 4H5CF 4DI5A 2Z4ZA 3CP6A 5HNAA 4KQUA 3IPIA 3LG5A 4LA6A 3WCEA 3SDTA 3VJBA 4H5EF 2ZEVA 2E91A 2FORA 1RQIA 4P0WA 5EATA 4GP1A 4OMGA 5EROA 4JZBA 1YHKA 1HXAA 5ILZA 2Q9ZA 3LLWA 3RYWA 3ZMBA 2Z50A 2AZKA 2OGDA 3LSNA 3NPRA 1N1BA 1WL2A 4ZQ8A 4LZ3A 2EWGA 3DYHA 4KKMA 2J5CA 5I1UA 4LFGA 4JZXA 4RXEA 3V1XA 5H9DA 5ILJA 5ERNA 1YHLA 4N9UA 1N22A 2ZCRA 3AQBB 2FTZA 2RAHA 1HXGA 2AZLA 2Z52A 4LLTA 2DH4A 5EASA 5A0IA 5E8LA 4GAXA 3S4JA 4RXCA 3ICMA 4P0VA 4KFAA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5DJV F;  1WY0 A;  4KQS A;  3TFP A;  2Z4W A;  3ZOU A;  3ZL6 A;  3ICN A;  1HXC A;  3KRF A;  3KRC B;  5IVG A;  3PYB A;  2E8U A;  4OMH A;  4RXD A;  4LPH F;  5IMN A;  5B0K A;  1EZF A;  1VG7 A;  3DYF A;  4E1E A;  4L2X F;  1N24 A;  5B0J A;  4Q23 A;  3ZCD A;  2F9K F;  2H8O A;  4LIX A;  4OKZ A;  1HM4 A;  1UBY A;  5DGN F;  2Q58 A;  3KRO A;  1JFG A;  4K10 A;  5AYP A;  2OA6 A;  5IK6 A;  3P5R A;  3WCH A;  2E93 A;  3KRP A;  3BNX A;  4DXJ A;  3VJ9 A;  1YYS A;  2O1O A;  4LXW A;  5B0L A;  4DWB A;  4KVD A;  3SDR A;  3WE9 A;  5HN9 A;  2OPN A;  4LTZ A;  3V1V A;  3N46 F;  1YYR A;  3OAB A;  2ONG A;  5ILY A;  2PS6 A;  4KVY A;  4LA5 A;  4UMJ A;  2PS4 A;  4NKE A;  3KRA A;  1YQ7 A;  5IK9 A;  5B00 A;  4RNQ A;  5AEL A;  4JVJ F;  3ACX A;  4NFJ F;  3ZMC A;  4KPJ A;  3KBK A;  5JA0 F;  5AHU B;  2Z7H A;  3BNY A;  1RQJ A;  1PS1 A;  2J1O A;  3CC9 A;  3WCL A;  3OYR A;  1ZW5 A;  3SDU A;  5IKA A;  5B0M A;  1UBW A;  4MC0 A;  3N5H F;  4FP4 A;  4LLS A;  4LPG F;  4WK5 A;  5C05 A;  1UBX A;  1VG3 A;  4P0X A;  5DW7 A;  2E95 A;  2E8V A;  3PKO A;  4NKF A;  2E8W A;  1V4H A;  3ID0 A;  3WSB A;  4E9U A;  2Q80 A;  3LVS A;  3TC1 A;  3M0G A;  3LJI A;  2Z78 A;  3OAC B;  3P41 A;  5A0K A;  3LEE A;  5DHK A;  5IL8 A;  5ERM A;  4HD1 A;  1WKZ A;  5ER8 A;  4NUA A;  4PVX F;  5ILI A;  1N21 A;  1KIZ A;  2PS5 A;  1V4E A;  4LOB A;  5AFX A;  4NFK F;  1V4K A;  4H5D F;  4LFE A;  5ILK A;  2P1C A;  2F8C F;  3Q2Q A;  2E4O A;  3M9U A;  5B03 A;  5IN8 A;  3AE0 A;  4EA1 A;  3SDQ A;  4DWG A;  4EA0 A;  2Z4X A;  3V66 A;  4F62 A;  5IK0 A;  3EZ3 A;  5JV2 F;  1KIY A;  3N3L F;  4XQT F;  3NPK A;  5HN7 A;  4LZC A;  4LFV F;  3Q1O A;  4XQS F;  4JXN A;  3SDV A;  4E9Z A;  3WEK A;  3RMG A;  4MC8 A;  2F92 F;  1V4J A;  3WCI A;  1YYQ A;  4QXS F;  3WEH A;  3VJD A;  3EGT A;  5DJR F;  1JFA A;  1YYT A;  3VJA A;  2AEK A;  5DGM F;  4NG6 A;  4EA2 A;  3WEJ A;  2F8Z F;  4JXY A;  4PVY F;  4QPF A;  3N5J F;  3WJK A;  3TFV A;  3EFQ A;  1YJ4 A;  3S9V A;  3Q2Z A;  5ILD A;  3LDW A;  4JYX A;  3ICK A;  2Z4Y A;  3IBA A;  3QKC A;  5E8H A;  5KSX F;  1V4I A;  1UBV A;  4OGU A;  2QIS A;  2ONH A;  3TS7 A;  2AET A;  4OKM A;  3N6K F;  3WCM A;  3KRF B;  2J1P A;  2Q9Y A;  1RTR A;  3N1W F;  3N0G A;  4DHD A;  3NF2 A;  5DZ2 A;  3ASX A;  3VJ8 A;  3WEF A;  3LZ9 A;  3CKE A;  4LTV A;  3WCB A;  5B01 A;  3VJC A;  1N20 A;  3WCG A;  5IMP A;  2ZCQ A;  3N3D A;  5A0J A;  3UCA A;  3KRO B;  5EAU A;  5JV0 F;  3KRC A;  1WMW A;  3WEG A;  3ICZ A;  3AQC B;  3AQ0 A;  1N23 A;  5ILH A;  4KUX A;  3KRP B;  3N0F A;  1YHM A;  3W7F A;  5DIQ F;  3LOM A;  3WSA A;  5B0I A;  3M01 A;  1WL1 A;  4KVI A;  4DEM F;  3QQV A;  5CG6 A;  4F6X A;  2F7M F;  2I19 A;  3MZV A;  3OAB B;  3WEI A;  4GP2 A;  3ADZ A;  3Q30 A;  3KRA B;  4XQR F;  1HX9 A;  5HN8 A;  3WJN A;  1VG4 A;  3N45 F;  3WCJ A;  3PYA A;  1WL0 A;  3B7L A;  2AEL A;  3RYE A;  2E92 A;  3DYG A;  3MAV A;  4KVW A;  3LK5 A;  3M00 A;  3LMD A;  3N49 F;  5IKH A;  4MC3 A;  1HM7 A;  5E8K A;  3WCA A;  3M02 A;  3WC9 A;  1YYU A;  3RBM A;  1WL3 A;  3KB9 A;  2ZEU A;  3P8R A;  4DZW A;  3ACW A;  5IMI A;  5JV1 F;  4KK2 A;  2PS8 A;  2E94 A;  2OPM A;  3PH7 A;  1FPS A;  2ZY1 A;  1VG2 A;  2F89 F;  3N1V F;  4GA3 A;  1VG6 A;  3LGK A;  5DJP F;  3APZ A;  2E8T A;  4FJQ A;  4LZ0 A;  5IL3 A;  5B02 A;  5JUZ F;  3P8L A;  4RXA A;  3LGZ B;  3TFN A;  4KQ5 A;  3WCF A;  1DGP A;  5CG5 A;  4RYP A;  2Z4V A;  3NRI A;  5DGS F;  4KPD A;  5DHI A;  2PS7 A;  1N1Z A;  3P5P A;  2E90 A;  2AZJ A;  5IM1 A;  2ZCS A;  4NFI F;  4F6V A;  3PDE A;  1YV5 A;  3ACY A;  3WCD A;  3G4F A;  4N1Z F;  3SAE A;  3OAC A;  2E8X A;  3WJO A;  4KWD A;  1DI1 A;  3VJE A;  3WCC A;  3G4D A;  2ZCO A;  4LUU A;  2VF6 A;  2Z7I A;  2F94 F;  4H5C F;  4DI5 A;  2Z4Z A;  3CP6 A;  5HNA A;  4KQU A;  3IPI A;  3LG5 A;  4LA6 A;  3WCE A;  3SDT A;  3VJB A;  4H5E F;  2ZEV A;  2E91 A;  2FOR A;  1RQI A;  4P0W A;  5EAT A;  4GP1 A;  4OMG A;  5ERO A;  4JZB A;  1YHK A;  1HXA A;  5ILZ A;  2Q9Z A;  3LLW A;  3RYW A;  3ZMB A;  2Z50 A;  2AZK A;  2OGD A;  3LSN A;  3NPR A;  1N1B A;  1WL2 A;  4ZQ8 A;  4LZ3 A;  2EWG A;  3DYH A;  4KKM A;  2J5C A;  5I1U A;  4LFG A;  4JZX A;  4RXE A;  3V1X A;  5H9D A;  5ILJ A;  5ERN A;  1YHL A;  4N9U A;  1N22 A;  2ZCR A;  3AQB B;  2FTZ A;  2RAH A;  1HXG A;  2AZL A;  2Z52 A;  4LLT A;  2DH4 A;  5EAS A;  5A0I A;  5E8L A;  4GAX A;  3S4J A;  4RXC A;  3ICM A;  4P0V A;  4KFA A; 
#chains in the Genus database with same CATH topology
 5DJV F;  1WY0 A;  4KQS A;  3TFP A;  2Z4W A;  3ZOU A;  3ZL6 A;  3ICN A;  1HXC A;  3KRF A;  3KRC B;  5IVG A;  3PYB A;  2E8U A;  4OMH A;  4RXD A;  4LPH F;  5IMN A;  5B0K A;  1EZF A;  1VG7 A;  3DYF A;  4E1E A;  4L2X F;  1N24 A;  5B0J A;  4Q23 A;  3ZCD A;  2F9K F;  2H8O A;  4LIX A;  4OKZ A;  1HM4 A;  1UBY A;  5DGN F;  2Q58 A;  3KRO A;  1JFG A;  4K10 A;  5AYP A;  2OA6 A;  5IK6 A;  3P5R A;  3WCH A;  2E93 A;  3KRP A;  3BNX A;  4DXJ A;  3VJ9 A;  1YYS A;  2O1O A;  4LXW A;  5B0L A;  4DWB A;  4KVD A;  3SDR A;  3WE9 A;  5HN9 A;  2OPN A;  4LTZ A;  3V1V A;  3N46 F;  1YYR A;  3OAB A;  2ONG A;  5ILY A;  2PS6 A;  4KVY A;  4LA5 A;  4UMJ A;  2PS4 A;  4NKE A;  3KRA A;  1YQ7 A;  5IK9 A;  5B00 A;  4RNQ A;  5AEL A;  4JVJ F;  3ACX A;  4NFJ F;  3ZMC A;  4KPJ A;  3KBK A;  5JA0 F;  5AHU B;  2Z7H A;  3BNY A;  1RQJ A;  1PS1 A;  2J1O A;  3CC9 A;  3WCL A;  3OYR A;  1ZW5 A;  3SDU A;  5IKA A;  5B0M A;  1UBW A;  4MC0 A;  3N5H F;  4FP4 A;  4LLS A;  4LPG F;  4WK5 A;  5C05 A;  1UBX A;  1VG3 A;  4P0X A;  5DW7 A;  2E95 A;  2E8V A;  3PKO A;  4NKF A;  2E8W A;  1V4H A;  3ID0 A;  3WSB A;  4E9U A;  2Q80 A;  3LVS A;  3TC1 A;  3M0G A;  3LJI A;  2Z78 A;  3OAC B;  3P41 A;  5A0K A;  3LEE A;  5DHK A;  5IL8 A;  5ERM A;  4HD1 A;  1WKZ A;  5ER8 A;  4NUA A;  4PVX F;  5ILI A;  1N21 A;  1KIZ A;  2PS5 A;  1V4E A;  4LOB A;  5AFX A;  4NFK F;  1V4K A;  4H5D F;  4LFE A;  5ILK A;  2P1C A;  2F8C F;  3Q2Q A;  2E4O A;  3M9U A;  5B03 A;  5IN8 A;  3AE0 A;  4EA1 A;  3SDQ A;  4DWG A;  4EA0 A;  2Z4X A;  3V66 A;  4F62 A;  5IK0 A;  3EZ3 A;  5JV2 F;  1KIY A;  3N3L F;  4XQT F;  3NPK A;  5HN7 A;  4LZC A;  4LFV F;  3Q1O A;  4XQS F;  4JXN A;  3SDV A;  4E9Z A;  3WEK A;  3RMG A;  4MC8 A;  2F92 F;  1V4J A;  3WCI A;  1YYQ A;  4QXS F;  3WEH A;  3VJD A;  3EGT A;  5DJR F;  1JFA A;  1YYT A;  3VJA A;  2AEK A;  5DGM F;  4NG6 A;  4EA2 A;  3WEJ A;  2F8Z F;  4JXY A;  4PVY F;  4QPF A;  3N5J F;  3WJK A;  3TFV A;  3EFQ A;  1YJ4 A;  3S9V A;  3Q2Z A;  5ILD A;  3LDW A;  4JYX A;  3ICK A;  2Z4Y A;  3IBA A;  3QKC A;  5E8H A;  5KSX F;  1V4I A;  1UBV A;  4OGU A;  2QIS A;  2ONH A;  3TS7 A;  2AET A;  4OKM A;  3N6K F;  3WCM A;  3KRF B;  2J1P A;  2Q9Y A;  1RTR A;  3N1W F;  3N0G A;  4DHD A;  3NF2 A;  5DZ2 A;  3ASX A;  3VJ8 A;  3WEF A;  3LZ9 A;  3CKE A;  4LTV A;  3WCB A;  5B01 A;  3VJC A;  1N20 A;  3WCG A;  5IMP A;  2ZCQ A;  3N3D A;  5A0J A;  3UCA A;  3KRO B;  5EAU A;  5JV0 F;  3KRC A;  1WMW A;  3WEG A;  3ICZ A;  3AQC B;  3AQ0 A;  1N23 A;  5ILH A;  4KUX A;  3KRP B;  3N0F A;  1YHM A;  3W7F A;  5DIQ F;  3LOM A;  3WSA A;  5B0I A;  3M01 A;  1WL1 A;  4KVI A;  4DEM F;  3QQV A;  5CG6 A;  4F6X A;  2F7M F;  2I19 A;  3MZV A;  3OAB B;  3WEI A;  4GP2 A;  3ADZ A;  3Q30 A;  3KRA B;  4XQR F;  1HX9 A;  5HN8 A;  3WJN A;  1VG4 A;  3N45 F;  3WCJ A;  3PYA A;  1WL0 A;  3B7L A;  2AEL A;  3RYE A;  2E92 A;  3DYG A;  3MAV A;  4KVW A;  3LK5 A;  3M00 A;  3LMD A;  3N49 F;  5IKH A;  4MC3 A;  1HM7 A;  5E8K A;  3WCA A;  3M02 A;  3WC9 A;  1YYU A;  3RBM A;  1WL3 A;  3KB9 A;  2ZEU A;  3P8R A;  4DZW A;  3ACW A;  5IMI A;  5JV1 F;  4KK2 A;  2PS8 A;  2E94 A;  2OPM A;  3PH7 A;  1FPS A;  2ZY1 A;  1VG2 A;  2F89 F;  3N1V F;  4GA3 A;  1VG6 A;  3LGK A;  5DJP F;  3APZ A;  2E8T A;  4FJQ A;  4LZ0 A;  5IL3 A;  5B02 A;  5JUZ F;  3P8L A;  4RXA A;  3LGZ B;  3TFN A;  4KQ5 A;  3WCF A;  1DGP A;  5CG5 A;  4RYP A;  2Z4V A;  3NRI A;  5DGS F;  4KPD A;  5DHI A;  2PS7 A;  1N1Z A;  3P5P A;  2E90 A;  2AZJ A;  5IM1 A;  2ZCS A;  4NFI F;  4F6V A;  3PDE A;  1YV5 A;  3ACY A;  3WCD A;  3G4F A;  4N1Z F;  3SAE A;  3OAC A;  2E8X A;  3WJO A;  4KWD A;  1DI1 A;  3VJE A;  3WCC A;  3G4D A;  2ZCO A;  4LUU A;  2VF6 A;  2Z7I A;  2F94 F;  4H5C F;  4DI5 A;  2Z4Z A;  3CP6 A;  5HNA A;  4KQU A;  3IPI A;  3LG5 A;  4LA6 A;  3WCE A;  3SDT A;  3VJB A;  4H5E F;  2ZEV A;  2E91 A;  2FOR A;  1RQI A;  4P0W A;  5EAT A;  4GP1 A;  4OMG A;  5ERO A;  4JZB A;  1YHK A;  1HXA A;  5ILZ A;  2Q9Z A;  3LLW A;  3RYW A;  3ZMB A;  2Z50 A;  2AZK A;  2OGD A;  3LSN A;  3NPR A;  1N1B A;  1WL2 A;  4ZQ8 A;  4LZ3 A;  2EWG A;  3DYH A;  4KKM A;  2J5C A;  5I1U A;  4LFG A;  4JZX A;  4RXE A;  3V1X A;  5H9D A;  5ILJ A;  5ERN A;  1YHL A;  4N9U A;  1N22 A;  2ZCR A;  3AQB B;  2FTZ A;  2RAH A;  1HXG A;  2AZL A;  2Z52 A;  4LLT A;  2DH4 A;  5EAS A;  5A0I A;  5E8L A;  4GAX A;  3S4J A;  4RXC A;  3ICM A;  4P0V A;  4KFA A; 
#chains in the Genus database with same CATH homology
 5DJV F;  1WY0 A;  4KQS A;  3TFP A;  2Z4W A;  3ZOU A;  3ZL6 A;  3ICN A;  1HXC A;  3KRF A;  3KRC B;  5IVG A;  3PYB A;  2E8U A;  4OMH A;  4RXD A;  4LPH F;  5IMN A;  5B0K A;  1EZF A;  1VG7 A;  3DYF A;  4E1E A;  4L2X F;  1N24 A;  5B0J A;  4Q23 A;  3ZCD A;  2F9K F;  2H8O A;  4LIX A;  4OKZ A;  1HM4 A;  1UBY A;  5DGN F;  2Q58 A;  3KRO A;  1JFG A;  4K10 A;  5AYP A;  2OA6 A;  5IK6 A;  3P5R A;  3WCH A;  2E93 A;  3KRP A;  3BNX A;  4DXJ A;  3VJ9 A;  1YYS A;  2O1O A;  4LXW A;  5B0L A;  4DWB A;  4KVD A;  3SDR A;  3WE9 A;  5HN9 A;  2OPN A;  4LTZ A;  3V1V A;  3N46 F;  1YYR A;  3OAB A;  2ONG A;  5ILY A;  2PS6 A;  4KVY A;  4LA5 A;  4UMJ A;  2PS4 A;  4NKE A;  3KRA A;  1YQ7 A;  5IK9 A;  5B00 A;  4RNQ A;  5AEL A;  4JVJ F;  3ACX A;  4NFJ F;  3ZMC A;  4KPJ A;  3KBK A;  5JA0 F;  5AHU B;  2Z7H A;  3BNY A;  1RQJ A;  1PS1 A;  2J1O A;  3CC9 A;  3WCL A;  3OYR A;  1ZW5 A;  3SDU A;  5IKA A;  5B0M A;  1UBW A;  4MC0 A;  3N5H F;  4FP4 A;  4LLS A;  4LPG F;  4WK5 A;  5C05 A;  1UBX A;  1VG3 A;  4P0X A;  5DW7 A;  2E95 A;  2E8V A;  3PKO A;  4NKF A;  2E8W A;  1V4H A;  3ID0 A;  3WSB A;  4E9U A;  2Q80 A;  3LVS A;  3TC1 A;  3M0G A;  3LJI A;  2Z78 A;  3OAC B;  3P41 A;  5A0K A;  3LEE A;  5DHK A;  5IL8 A;  5ERM A;  4HD1 A;  1WKZ A;  5ER8 A;  4NUA A;  4PVX F;  5ILI A;  1N21 A;  1KIZ A;  2PS5 A;  1V4E A;  4LOB A;  5AFX A;  4NFK F;  1V4K A;  4H5D F;  4LFE A;  5ILK A;  2P1C A;  2F8C F;  3Q2Q A;  2E4O A;  3M9U A;  5B03 A;  5IN8 A;  3AE0 A;  4EA1 A;  3SDQ A;  4DWG A;  4EA0 A;  2Z4X A;  3V66 A;  4F62 A;  5IK0 A;  3EZ3 A;  5JV2 F;  1KIY A;  3N3L F;  4XQT F;  3NPK A;  5HN7 A;  4LZC A;  4LFV F;  3Q1O A;  4XQS F;  4JXN A;  3SDV A;  4E9Z A;  3WEK A;  3RMG A;  4MC8 A;  2F92 F;  1V4J A;  3WCI A;  1YYQ A;  4QXS F;  3WEH A;  3VJD A;  3EGT A;  5DJR F;  1JFA A;  1YYT A;  3VJA A;  2AEK A;  5DGM F;  4NG6 A;  4EA2 A;  3WEJ A;  2F8Z F;  4JXY A;  4PVY F;  4QPF A;  3N5J F;  3WJK A;  3TFV A;  3EFQ A;  1YJ4 A;  3S9V A;  3Q2Z A;  5ILD A;  3LDW A;  4JYX A;  3ICK A;  2Z4Y A;  3IBA A;  3QKC A;  5E8H A;  5KSX F;  1V4I A;  1UBV A;  4OGU A;  2QIS A;  2ONH A;  3TS7 A;  2AET A;  4OKM A;  3N6K F;  3WCM A;  3KRF B;  2J1P A;  2Q9Y A;  1RTR A;  3N1W F;  3N0G A;  4DHD A;  3NF2 A;  5DZ2 A;  3ASX A;  3VJ8 A;  3WEF A;  3LZ9 A;  3CKE A;  4LTV A;  3WCB A;  5B01 A;  3VJC A;  1N20 A;  3WCG A;  5IMP A;  2ZCQ A;  3N3D A;  5A0J A;  3UCA A;  3KRO B;  5EAU A;  5JV0 F;  3KRC A;  1WMW A;  3WEG A;  3ICZ A;  3AQC B;  3AQ0 A;  1N23 A;  5ILH A;  4KUX A;  3KRP B;  3N0F A;  1YHM A;  3W7F A;  5DIQ F;  3LOM A;  3WSA A;  5B0I A;  3M01 A;  1WL1 A;  4KVI A;  4DEM F;  3QQV A;  5CG6 A;  4F6X A;  2F7M F;  2I19 A;  3MZV A;  3OAB B;  3WEI A;  4GP2 A;  3ADZ A;  3Q30 A;  3KRA B;  4XQR F;  1HX9 A;  5HN8 A;  3WJN A;  1VG4 A;  3N45 F;  3WCJ A;  3PYA A;  1WL0 A;  3B7L A;  2AEL A;  3RYE A;  2E92 A;  3DYG A;  3MAV A;  4KVW A;  3LK5 A;  3M00 A;  3LMD A;  3N49 F;  5IKH A;  4MC3 A;  1HM7 A;  5E8K A;  3WCA A;  3M02 A;  3WC9 A;  1YYU A;  3RBM A;  1WL3 A;  3KB9 A;  2ZEU A;  3P8R A;  4DZW A;  3ACW A;  5IMI A;  5JV1 F;  4KK2 A;  2PS8 A;  2E94 A;  2OPM A;  3PH7 A;  1FPS A;  2ZY1 A;  1VG2 A;  2F89 F;  3N1V F;  4GA3 A;  1VG6 A;  3LGK A;  5DJP F;  3APZ A;  2E8T A;  4FJQ A;  4LZ0 A;  5IL3 A;  5B02 A;  5JUZ F;  3P8L A;  4RXA A;  3LGZ B;  3TFN A;  4KQ5 A;  3WCF A;  1DGP A;  5CG5 A;  4RYP A;  2Z4V A;  3NRI A;  5DGS F;  4KPD A;  5DHI A;  2PS7 A;  1N1Z A;  3P5P A;  2E90 A;  2AZJ A;  5IM1 A;  2ZCS A;  4NFI F;  4F6V A;  3PDE A;  1YV5 A;  3ACY A;  3WCD A;  3G4F A;  4N1Z F;  3SAE A;  3OAC A;  2E8X A;  3WJO A;  4KWD A;  1DI1 A;  3VJE A;  3WCC A;  3G4D A;  2ZCO A;  4LUU A;  2VF6 A;  2Z7I A;  2F94 F;  4H5C F;  4DI5 A;  2Z4Z A;  3CP6 A;  5HNA A;  4KQU A;  3IPI A;  3LG5 A;  4LA6 A;  3WCE A;  3SDT A;  3VJB A;  4H5E F;  2ZEV A;  2E91 A;  2FOR A;  1RQI A;  4P0W A;  5EAT A;  4GP1 A;  4OMG A;  5ERO A;  4JZB A;  1YHK A;  1HXA A;  5ILZ A;  2Q9Z A;  3LLW A;  3RYW A;  3ZMB A;  2Z50 A;  2AZK A;  2OGD A;  3LSN A;  3NPR A;  1N1B A;  1WL2 A;  4ZQ8 A;  4LZ3 A;  2EWG A;  3DYH A;  4KKM A;  2J5C A;  5I1U A;  4LFG A;  4JZX A;  4RXE A;  3V1X A;  5H9D A;  5ILJ A;  5ERN A;  1YHL A;  4N9U A;  1N22 A;  2ZCR A;  3AQB B;  2FTZ A;  2RAH A;  1HXG A;  2AZL A;  2Z52 A;  4LLT A;  2DH4 A;  5EAS A;  5A0I A;  5E8L A;  4GAX A;  3S4J A;  4RXC A;  3ICM A;  4P0V A;  4KFA A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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