5CG5A

Neutron crystal structure of human farnesyl pyrophosphate synthase in complex with risedronate
Total Genus 143
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
143
sequence length
343
structure length
342
Chain Sequence
DVYAQEKQDFVQHFSQIVRVLTEDEMGHPEIGDAIARLKEVLEYNAIGGKYNRGLTVVVAFRELVEPRKQDADSLQRAWTVGWCVELLAFFLVADDIMDSSLTRRGQICWYQKPGVGLDAINDANLLEACIYRLLKLYCREQPYYLNLIELFLQSSYQTEIGQTLDLLTAPQGNVDLVRFTEKRYKSIVKYKTAFYSFYLPIAAAMYMAGIDGEKEHANAKKILLEMGEFFQIQDDYLDLFGDPSVTGKIGTDIQDNKCSWLVVQCLQRATPEQYQILKENYGQKEAEKVARVKALYEELDLPAVFLQYEEDSYSHIMALIEQYAAPLPPAVFLGLARKIYK
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Protonation State and Hydration of Bisphosphonate Bound to Farnesyl Pyrophosphate Synthase
pubmed doi rcsb
molecule tags Transferase/transferase inhibotor
source organism Homo sapiens
molecule keywords Farnesyl pyrophosphate synthase
total genus 143
structure length 342
sequence length 343
ec nomenclature ec 2.5.1.1: Dimethylallyltranstransferase.
pdb deposition date 2015-07-09

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00348 polyprenyl_synt Polyprenyl synthetase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.600.10 Mainly Alpha Orthogonal Bundle Farnesyl Diphosphate Synthase Farnesyl Diphosphate Synthase 5cg5A00
3LDWA 2P1CA 3QKCA 1WL1A 3DYGA 1HXAA 3LGKA 5HN9A 3WCBA 4DWBA 4MC0A 1HXGA 2VF6A 5B0KA 4K10A 3DYFA 3ICNA 4JXYA 3ZMBA 4NFJF 5IKAA 2OA6A 1V4IA 4LXWA 4ZQ8A 1WL2A 2AZKA 3WCDA 4LTVA 1YYTA 3WC9A 1YYSA 5IKHA 4GAXA 4QXSF 5IL8A 3WCGA 3KRPB 4OMGA 5E8LA 2F8ZF 3ZCDA 2PS4A 3LK5A 3KROA 5AYPA 2F89F 3N45F 3PKOA 3SAEA 4KQ5A 4E1EA 1YHMA 3ACWA 5ER8A 3ADZA 1YYUA 4UMJA 2Z4VA 4L2XF 3RBMA 5B0JA 2AZLA 2ONGA 1WKZA 4OGUA 2E92A 4KVYA 4QPFA 2OPMA 1V4HA 3WJKA 5A0IA 4LFEA 2PS5A 3LJIA 3KB9A 3N6KF 3ICKA 3RYEA 3S9VA 4EA2A 4KUXA 4H5DF 4Q23A 4KWDA 4NUAA 5IMPA 2Z7IA 3N0FA 3N3LF 4RXCA 4PVYF 3P5RA 3KRPA 3WCJA 2F7MF 5AHUB 3NRIA 3ACYA 4OKMA 4KVWA 1EZFA 3KRAB 5B0IA 4F62A 3M0GA 4LZ0A 3NF2A 1N24A 3WEGA 1UBWA 4XQSF 3RMGA 3TFNA 1YYQA 4KVDA 4DHDA 1WL0A 1N23A 2J5CA 2J1PA 2FTZA 1JFAA 5IVGA 5AELA 4DXJA 3TFVA 1VG7A 2RAHA 4GP1A 2E91A 1WY0A 3OACB 2F94F 2F92F 4RXAA 3PYBA 1VG3A 5E8HA 3VJBA 2F8CF 2ZCQA 3M00A 5I1UA 2Z4ZA 5DGMF 5JUZF 2E93A 5B00A 3KRAA 5AFXA 4E9ZA 3BNYA 5HN7A 4RNQA 5IL3A 2H8OA 3KRFB 1V4JA 5B01A 3WEJA 1KIZA 4XQRF 3V1VA 3IPIA 3WE9A 4P0VA 3NPRA 4LLTA 2I19A 1UBYA 5DHIA 4LUUA 3ZOUA 2E8TA 3MAVA 3LGZB 3ID0A 2AEKA 2E8UA 3EGTA 3N5HF 1DGPA 2EWGA 3VJ9A 5IK6A 3WEKA 4LZ3A 5DJVF 2ONHA 1V4KA 2ZY1A 1V4EA 2Q9YA 2PS7A 2ZCOA 5HN8A 4NFIF 2J1OA 5JV2F 2Z7HA 5IK9A 5EROA 5ILDA 5DW7A 3KRFA 5DJPF 4LOBA 2ZEUA 3LOMA 1ZW5A 3AE0A 3SDVA 3MZVA 4KFAA 3VJEA 4MC3A 5CG6A 2AETA 3UCAA 4F6VA 2E4OA 3ICZA 1WL3A 2E94A 3WEFA 3N1VF 2AELA 2Z4XA 5JA0F 3APZA 4GP2A 2E8VA 3NPKA 3WCLA 5DHKA 1YJ4A 1UBVA 4DEMF 4PVXF 3WEIA 2Q9ZA 3CP6A 5ILZA 5EATA 3OABB 4NKEA 2ZCRA 3TC1A 1FPSA 4FJQA 1N22A 3ICMA 3SDTA 3LLWA 5B03A 3WCFA 3N46F 5B0LA 4DZWA 3EFQA 3WJNA 3PDEA 4LPHF 1HM7A 5B02A 4JXNA 3Q30A 5E8KA 1RTRA 5DZ2A 2DH4A 3PH7A 4F6XA 1VG6A 5IMNA 1YV5A 4DWGA 3ZL6A 3M02A 4JYXA 4NKFA 2FORA 3ACXA 3P8LA 1PS1A 3DYHA 3OABA 4N9UA 5IM1A 4LTZA 3B7LA 3CC9A 3ZMCA 1WMWA 3P8RA 4NFKF 2OGDA 1YQ7A 3WJOA 3AQ0A 3LVSA 2O1OA 4KKMA 2E90A 3Q2QA 1RQJA 2Z50A 3LMDA 3KBKA 3OACA 1YHKA 1YHLA 3SDUA 5IN8A 1JFGA 2Z52A 4XQTF 3SDQA 3WSBA 4H5CF 2QISA 2E95A 5JV1F 4KQSA 3WCCA 3P41A 4GA3A 2PS8A 2ZEVA 3LG5A 3PYAA 3N0GA 1UBXA 2E8XA 3QQVA 4MC8A 5CG5A 1DI1A 3VJ8A 5ILJA 4RXEA 5ILYA 3Q2ZA 2Z78A 3N1WF 5HNAA 5ERMA 4JZXA 5EAUA 2Z4WA 4JVJF 1N1ZA 1VG4A 3CKEA 4RYPA 3WCHA 5ILHA 3IBAA 3N49F 5IK0A 4KQUA 4LFVF 4LZCA 4P0WA 4LPGF 4KVIA 4N1ZF 1YYRA 3WCEA 3WSAA 2AZJA 2PS6A 3V66A 4H5EF 4E9UA 5ILKA 3OYRA 3S4JA 3G4DA 2Z4YA 5EASA 3VJAA 3WCMA 3KRCB 4HD1A 3G4FA 5A0JA 3P5PA 4LIXA 3M01A 4LA5A 4P0XA 1HX9A 4FP4A 1VG2A 1HXCA 4OMHA 5KSXF 4JZBA 4KPJA 5A0KA 5ILIA 4LLSA 5DIQF 4NG6A 3WEHA 5DGNF 2ZCSA 3SDRA 5C05A 4WK5A 3LSNA 5IMIA 4OKZA 4LFGA 3W7FA 5H9DA 3ASXA 1N20A 3AQCB 4DI5A 1N21A 3RYWA 3V1XA 1RQIA 1HM4A 2Q58A 3LEEA 4KPDA 5JV0F 3N3DA 4EA0A 5DGSF 5DJRF 3TFPA 3EZ3A 5B0MA 2Q80A 3VJCA 3N5JF 3KRCA 3LZ9A 3M9UA 4LA6A 5ERNA 2OPNA 3WCIA 4KK2A 2E8WA 3KROB 3WCAA 3BNXA 3VJDA 3AQBB 3Q1OA 3TS7A 2F9KF 1N1BA 4RXDA 1KIYA 4EA1A
chains in the Genus database with same CATH superfamily
3LDWA 2P1CA 3QKCA 1WL1A 3DYGA 1HXAA 3LGKA 5HN9A 3WCBA 4DWBA 4MC0A 1HXGA 2VF6A 5B0KA 4K10A 3DYFA 3ICNA 4JXYA 3ZMBA 4NFJF 5IKAA 2OA6A 1V4IA 4LXWA 4ZQ8A 1WL2A 2AZKA 3WCDA 4LTVA 1YYTA 3WC9A 1YYSA 5IKHA 4GAXA 4QXSF 5IL8A 3WCGA 3KRPB 4OMGA 5E8LA 2F8ZF 3ZCDA 2PS4A 3LK5A 3KROA 5AYPA 2F89F 3N45F 3PKOA 3SAEA 4KQ5A 4E1EA 1YHMA 3ACWA 5ER8A 3ADZA 1YYUA 4UMJA 2Z4VA 4L2XF 3RBMA 5B0JA 2AZLA 2ONGA 1WKZA 4OGUA 2E92A 4KVYA 4QPFA 2OPMA 1V4HA 3WJKA 5A0IA 4LFEA 2PS5A 3LJIA 3KB9A 3N6KF 3ICKA 3RYEA 3S9VA 4EA2A 4KUXA 4H5DF 4Q23A 4KWDA 4NUAA 5IMPA 2Z7IA 3N0FA 3N3LF 4RXCA 4PVYF 3P5RA 3KRPA 3WCJA 2F7MF 5AHUB 3NRIA 3ACYA 4OKMA 4KVWA 1EZFA 3KRAB 5B0IA 4F62A 3M0GA 4LZ0A 3NF2A 1N24A 3WEGA 1UBWA 4XQSF 3RMGA 3TFNA 1YYQA 4KVDA 4DHDA 1WL0A 1N23A 2J5CA 2J1PA 2FTZA 1JFAA 5IVGA 5AELA 4DXJA 3TFVA 1VG7A 2RAHA 4GP1A 2E91A 1WY0A 3OACB 2F94F 2F92F 4RXAA 3PYBA 1VG3A 5E8HA 3VJBA 2F8CF 2ZCQA 3M00A 5I1UA 2Z4ZA 5DGMF 5JUZF 2E93A 5B00A 3KRAA 5AFXA 4E9ZA 3BNYA 5HN7A 4RNQA 5IL3A 2H8OA 3KRFB 1V4JA 5B01A 3WEJA 1KIZA 4XQRF 3V1VA 3IPIA 3WE9A 4P0VA 3NPRA 4LLTA 2I19A 1UBYA 5DHIA 4LUUA 3ZOUA 2E8TA 3MAVA 3LGZB 3ID0A 2AEKA 2E8UA 3EGTA 3N5HF 1DGPA 2EWGA 3VJ9A 5IK6A 3WEKA 4LZ3A 5DJVF 2ONHA 1V4KA 2ZY1A 1V4EA 2Q9YA 2PS7A 2ZCOA 5HN8A 4NFIF 2J1OA 5JV2F 2Z7HA 5IK9A 5EROA 5ILDA 5DW7A 3KRFA 5DJPF 4LOBA 2ZEUA 3LOMA 1ZW5A 3AE0A 3SDVA 3MZVA 4KFAA 3VJEA 4MC3A 5CG6A 2AETA 3UCAA 4F6VA 2E4OA 3ICZA 1WL3A 2E94A 3WEFA 3N1VF 2AELA 2Z4XA 5JA0F 3APZA 4GP2A 2E8VA 3NPKA 3WCLA 5DHKA 1YJ4A 1UBVA 4DEMF 4PVXF 3WEIA 2Q9ZA 3CP6A 5ILZA 5EATA 3OABB 4NKEA 2ZCRA 3TC1A 1FPSA 4FJQA 1N22A 3ICMA 3SDTA 3LLWA 5B03A 3WCFA 3N46F 5B0LA 4DZWA 3EFQA 3WJNA 3PDEA 4LPHF 1HM7A 5B02A 4JXNA 3Q30A 5E8KA 1RTRA 5DZ2A 2DH4A 3PH7A 4F6XA 1VG6A 5IMNA 1YV5A 4DWGA 3ZL6A 3M02A 4JYXA 4NKFA 2FORA 3ACXA 3P8LA 1PS1A 3DYHA 3OABA 4N9UA 5IM1A 4LTZA 3B7LA 3CC9A 3ZMCA 1WMWA 3P8RA 4NFKF 2OGDA 1YQ7A 3WJOA 3AQ0A 3LVSA 2O1OA 4KKMA 2E90A 3Q2QA 1RQJA 2Z50A 3LMDA 3KBKA 3OACA 1YHKA 1YHLA 3SDUA 5IN8A 1JFGA 2Z52A 4XQTF 3SDQA 3WSBA 4H5CF 2QISA 2E95A 5JV1F 4KQSA 3WCCA 3P41A 4GA3A 2PS8A 2ZEVA 3LG5A 3PYAA 3N0GA 1UBXA 2E8XA 3QQVA 4MC8A 5CG5A 1DI1A 3VJ8A 5ILJA 4RXEA 5ILYA 3Q2ZA 2Z78A 3N1WF 5HNAA 5ERMA 4JZXA 5EAUA 2Z4WA 4JVJF 1N1ZA 1VG4A 3CKEA 4RYPA 3WCHA 5ILHA 3IBAA 3N49F 5IK0A 4KQUA 4LFVF 4LZCA 4P0WA 4LPGF 4KVIA 4N1ZF 1YYRA 3WCEA 3WSAA 2AZJA 2PS6A 3V66A 4H5EF 4E9UA 5ILKA 3OYRA 3S4JA 3G4DA 2Z4YA 5EASA 3VJAA 3WCMA 3KRCB 4HD1A 3G4FA 5A0JA 3P5PA 4LIXA 3M01A 4LA5A 4P0XA 1HX9A 4FP4A 1VG2A 1HXCA 4OMHA 5KSXF 4JZBA 4KPJA 5A0KA 5ILIA 4LLSA 5DIQF 4NG6A 3WEHA 5DGNF 2ZCSA 3SDRA 5C05A 4WK5A 3LSNA 5IMIA 4OKZA 4LFGA 3W7FA 5H9DA 3ASXA 1N20A 3AQCB 4DI5A 1N21A 3RYWA 3V1XA 1RQIA 1HM4A 2Q58A 3LEEA 4KPDA 5JV0F 3N3DA 4EA0A 5DGSF 5DJRF 3TFPA 3EZ3A 5B0MA 2Q80A 3VJCA 3N5JF 3KRCA 3LZ9A 3M9UA 4LA6A 5ERNA 2OPNA 3WCIA 4KK2A 2E8WA 3KROB 3WCAA 3BNXA 3VJDA 3AQBB 3Q1OA 3TS7A 2F9KF 1N1BA 4RXDA 1KIYA 4EA1A
chains in the Genus database with same CATH topology
3LDWA 2P1CA 3QKCA 1WL1A 3DYGA 1HXAA 3LGKA 5HN9A 3WCBA 4DWBA 4MC0A 1HXGA 2VF6A 5B0KA 4K10A 3DYFA 3ICNA 4JXYA 3ZMBA 4NFJF 5IKAA 2OA6A 1V4IA 4LXWA 4ZQ8A 1WL2A 2AZKA 3WCDA 4LTVA 1YYTA 3WC9A 1YYSA 5IKHA 4GAXA 4QXSF 5IL8A 3WCGA 3KRPB 4OMGA 5E8LA 2F8ZF 3ZCDA 2PS4A 3LK5A 3KROA 5AYPA 2F89F 3N45F 3PKOA 3SAEA 4KQ5A 4E1EA 1YHMA 3ACWA 5ER8A 3ADZA 1YYUA 4UMJA 2Z4VA 4L2XF 3RBMA 5B0JA 2AZLA 2ONGA 1WKZA 4OGUA 2E92A 4KVYA 4QPFA 2OPMA 1V4HA 3WJKA 5A0IA 4LFEA 2PS5A 3LJIA 3KB9A 3N6KF 3ICKA 3RYEA 3S9VA 4EA2A 4KUXA 4H5DF 4Q23A 4KWDA 4NUAA 5IMPA 2Z7IA 3N0FA 3N3LF 4RXCA 4PVYF 3P5RA 3KRPA 3WCJA 2F7MF 5AHUB 3NRIA 3ACYA 4OKMA 4KVWA 1EZFA 3KRAB 5B0IA 4F62A 3M0GA 4LZ0A 3NF2A 1N24A 3WEGA 1UBWA 4XQSF 3RMGA 3TFNA 1YYQA 4KVDA 4DHDA 1WL0A 1N23A 2J5CA 2J1PA 2FTZA 1JFAA 5IVGA 5AELA 4DXJA 3TFVA 1VG7A 2RAHA 4GP1A 2E91A 1WY0A 3OACB 2F94F 2F92F 4RXAA 3PYBA 1VG3A 5E8HA 3VJBA 2F8CF 2ZCQA 3M00A 5I1UA 2Z4ZA 5DGMF 5JUZF 2E93A 5B00A 3KRAA 5AFXA 4E9ZA 3BNYA 5HN7A 4RNQA 5IL3A 2H8OA 3KRFB 1V4JA 5B01A 3WEJA 1KIZA 4XQRF 3V1VA 3IPIA 3WE9A 4P0VA 3NPRA 4LLTA 2I19A 1UBYA 5DHIA 4LUUA 3ZOUA 2E8TA 3MAVA 3LGZB 3ID0A 2AEKA 2E8UA 3EGTA 3N5HF 1DGPA 2EWGA 3VJ9A 5IK6A 3WEKA 4LZ3A 5DJVF 2ONHA 1V4KA 2ZY1A 1V4EA 2Q9YA 2PS7A 2ZCOA 5HN8A 4NFIF 2J1OA 5JV2F 2Z7HA 5IK9A 5EROA 5ILDA 5DW7A 3KRFA 5DJPF 4LOBA 2ZEUA 3LOMA 1ZW5A 3AE0A 3SDVA 3MZVA 4KFAA 3VJEA 4MC3A 5CG6A 2AETA 3UCAA 4F6VA 2E4OA 3ICZA 1WL3A 2E94A 3WEFA 3N1VF 2AELA 2Z4XA 5JA0F 3APZA 4GP2A 2E8VA 3NPKA 3WCLA 5DHKA 1YJ4A 1UBVA 4DEMF 4PVXF 3WEIA 2Q9ZA 3CP6A 5ILZA 5EATA 3OABB 4NKEA 2ZCRA 3TC1A 1FPSA 4FJQA 1N22A 3ICMA 3SDTA 3LLWA 5B03A 3WCFA 3N46F 5B0LA 4DZWA 3EFQA 3WJNA 3PDEA 4LPHF 1HM7A 5B02A 4JXNA 3Q30A 5E8KA 1RTRA 5DZ2A 2DH4A 3PH7A 4F6XA 1VG6A 5IMNA 1YV5A 4DWGA 3ZL6A 3M02A 4JYXA 4NKFA 2FORA 3ACXA 3P8LA 1PS1A 3DYHA 3OABA 4N9UA 5IM1A 4LTZA 3B7LA 3CC9A 3ZMCA 1WMWA 3P8RA 4NFKF 2OGDA 1YQ7A 3WJOA 3AQ0A 3LVSA 2O1OA 4KKMA 2E90A 3Q2QA 1RQJA 2Z50A 3LMDA 3KBKA 3OACA 1YHKA 1YHLA 3SDUA 5IN8A 1JFGA 2Z52A 4XQTF 3SDQA 3WSBA 4H5CF 2QISA 2E95A 5JV1F 4KQSA 3WCCA 3P41A 4GA3A 2PS8A 2ZEVA 3LG5A 3PYAA 3N0GA 1UBXA 2E8XA 3QQVA 4MC8A 5CG5A 1DI1A 3VJ8A 5ILJA 4RXEA 5ILYA 3Q2ZA 2Z78A 3N1WF 5HNAA 5ERMA 4JZXA 5EAUA 2Z4WA 4JVJF 1N1ZA 1VG4A 3CKEA 4RYPA 3WCHA 5ILHA 3IBAA 3N49F 5IK0A 4KQUA 4LFVF 4LZCA 4P0WA 4LPGF 4KVIA 4N1ZF 1YYRA 3WCEA 3WSAA 2AZJA 2PS6A 3V66A 4H5EF 4E9UA 5ILKA 3OYRA 3S4JA 3G4DA 2Z4YA 5EASA 3VJAA 3WCMA 3KRCB 4HD1A 3G4FA 5A0JA 3P5PA 4LIXA 3M01A 4LA5A 4P0XA 1HX9A 4FP4A 1VG2A 1HXCA 4OMHA 5KSXF 4JZBA 4KPJA 5A0KA 5ILIA 4LLSA 5DIQF 4NG6A 3WEHA 5DGNF 2ZCSA 3SDRA 5C05A 4WK5A 3LSNA 5IMIA 4OKZA 4LFGA 3W7FA 5H9DA 3ASXA 1N20A 3AQCB 4DI5A 1N21A 3RYWA 3V1XA 1RQIA 1HM4A 2Q58A 3LEEA 4KPDA 5JV0F 3N3DA 4EA0A 5DGSF 5DJRF 3TFPA 3EZ3A 5B0MA 2Q80A 3VJCA 3N5JF 3KRCA 3LZ9A 3M9UA 4LA6A 5ERNA 2OPNA 3WCIA 4KK2A 2E8WA 3KROB 3WCAA 3BNXA 3VJDA 3AQBB 3Q1OA 3TS7A 2F9KF 1N1BA 4RXDA 1KIYA 4EA1A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3LDW A;  2P1C A;  3QKC A;  1WL1 A;  3DYG A;  1HXA A;  3LGK A;  5HN9 A;  3WCB A;  4DWB A;  4MC0 A;  1HXG A;  2VF6 A;  5B0K A;  4K10 A;  3DYF A;  3ICN A;  4JXY A;  3ZMB A;  4NFJ F;  5IKA A;  2OA6 A;  1V4I A;  4LXW A;  4ZQ8 A;  1WL2 A;  2AZK A;  3WCD A;  4LTV A;  1YYT A;  3WC9 A;  1YYS A;  5IKH A;  4GAX A;  4QXS F;  5IL8 A;  3WCG A;  3KRP B;  4OMG A;  5E8L A;  2F8Z F;  3ZCD A;  2PS4 A;  3LK5 A;  3KRO A;  5AYP A;  2F89 F;  3N45 F;  3PKO A;  3SAE A;  4KQ5 A;  4E1E A;  1YHM A;  3ACW A;  5ER8 A;  3ADZ A;  1YYU A;  4UMJ A;  2Z4V A;  4L2X F;  3RBM A;  5B0J A;  2AZL A;  2ONG A;  1WKZ A;  4OGU A;  2E92 A;  4KVY A;  4QPF A;  2OPM A;  1V4H A;  3WJK A;  5A0I A;  4LFE A;  2PS5 A;  3LJI A;  3KB9 A;  3N6K F;  3ICK A;  3RYE A;  3S9V A;  4EA2 A;  4KUX A;  4H5D F;  4Q23 A;  4KWD A;  4NUA A;  5IMP A;  2Z7I A;  3N0F A;  3N3L F;  4RXC A;  4PVY F;  3P5R A;  3KRP A;  3WCJ A;  2F7M F;  5AHU B;  3NRI A;  3ACY A;  4OKM A;  4KVW A;  1EZF A;  3KRA B;  5B0I A;  4F62 A;  3M0G A;  4LZ0 A;  3NF2 A;  1N24 A;  3WEG A;  1UBW A;  4XQS F;  3RMG A;  3TFN A;  1YYQ A;  4KVD A;  4DHD A;  1WL0 A;  1N23 A;  2J5C A;  2J1P A;  2FTZ A;  1JFA A;  5IVG A;  5AEL A;  4DXJ A;  3TFV A;  1VG7 A;  2RAH A;  4GP1 A;  2E91 A;  1WY0 A;  3OAC B;  2F94 F;  2F92 F;  4RXA A;  3PYB A;  1VG3 A;  5E8H A;  3VJB A;  2F8C F;  2ZCQ A;  3M00 A;  5I1U A;  2Z4Z A;  5DGM F;  5JUZ F;  2E93 A;  5B00 A;  3KRA A;  5AFX A;  4E9Z A;  3BNY A;  5HN7 A;  4RNQ A;  5IL3 A;  2H8O A;  3KRF B;  1V4J A;  5B01 A;  3WEJ A;  1KIZ A;  4XQR F;  3V1V A;  3IPI A;  3WE9 A;  4P0V A;  3NPR A;  4LLT A;  2I19 A;  1UBY A;  5DHI A;  4LUU A;  3ZOU A;  2E8T A;  3MAV A;  3LGZ B;  3ID0 A;  2AEK A;  2E8U A;  3EGT A;  3N5H F;  1DGP A;  2EWG A;  3VJ9 A;  5IK6 A;  3WEK A;  4LZ3 A;  5DJV F;  2ONH A;  1V4K A;  2ZY1 A;  1V4E A;  2Q9Y A;  2PS7 A;  2ZCO A;  5HN8 A;  4NFI F;  2J1O A;  5JV2 F;  2Z7H A;  5IK9 A;  5ERO A;  5ILD A;  5DW7 A;  3KRF A;  5DJP F;  4LOB A;  2ZEU A;  3LOM A;  1ZW5 A;  3AE0 A;  3SDV A;  3MZV A;  4KFA A;  3VJE A;  4MC3 A;  5CG6 A;  2AET A;  3UCA A;  4F6V A;  2E4O A;  3ICZ A;  1WL3 A;  2E94 A;  3WEF A;  3N1V F;  2AEL A;  2Z4X A;  5JA0 F;  3APZ A;  4GP2 A;  2E8V A;  3NPK A;  3WCL A;  5DHK A;  1YJ4 A;  1UBV A;  4DEM F;  4PVX F;  3WEI A;  2Q9Z A;  3CP6 A;  5ILZ A;  5EAT A;  3OAB B;  4NKE A;  2ZCR A;  3TC1 A;  1FPS A;  4FJQ A;  1N22 A;  3ICM A;  3SDT A;  3LLW A;  5B03 A;  3WCF A;  3N46 F;  5B0L A;  4DZW A;  3EFQ A;  3WJN A;  3PDE A;  4LPH F;  1HM7 A;  5B02 A;  4JXN A;  3Q30 A;  5E8K A;  1RTR A;  5DZ2 A;  2DH4 A;  3PH7 A;  4F6X A;  1VG6 A;  5IMN A;  1YV5 A;  4DWG A;  3ZL6 A;  3M02 A;  4JYX A;  4NKF A;  2FOR A;  3ACX A;  3P8L A;  1PS1 A;  3DYH A;  3OAB A;  4N9U A;  5IM1 A;  4LTZ A;  3B7L A;  3CC9 A;  3ZMC A;  1WMW A;  3P8R A;  4NFK F;  2OGD A;  1YQ7 A;  3WJO A;  3AQ0 A;  3LVS A;  2O1O A;  4KKM A;  2E90 A;  3Q2Q A;  1RQJ A;  2Z50 A;  3LMD A;  3KBK A;  3OAC A;  1YHK A;  1YHL A;  3SDU A;  5IN8 A;  1JFG A;  2Z52 A;  4XQT F;  3SDQ A;  3WSB A;  4H5C F;  2QIS A;  2E95 A;  5JV1 F;  4KQS A;  3WCC A;  3P41 A;  4GA3 A;  2PS8 A;  2ZEV A;  3LG5 A;  3PYA A;  3N0G A;  1UBX A;  2E8X A;  3QQV A;  4MC8 A;  5CG5 A;  1DI1 A;  3VJ8 A;  5ILJ A;  4RXE A;  5ILY A;  3Q2Z A;  2Z78 A;  3N1W F;  5HNA A;  5ERM A;  4JZX A;  5EAU A;  2Z4W A;  4JVJ F;  1N1Z A;  1VG4 A;  3CKE A;  4RYP A;  3WCH A;  5ILH A;  3IBA A;  3N49 F;  5IK0 A;  4KQU A;  4LFV F;  4LZC A;  4P0W A;  4LPG F;  4KVI A;  4N1Z F;  1YYR A;  3WCE A;  3WSA A;  2AZJ A;  2PS6 A;  3V66 A;  4H5E F;  4E9U A;  5ILK A;  3OYR A;  3S4J A;  3G4D A;  2Z4Y A;  5EAS A;  3VJA A;  3WCM A;  3KRC B;  4HD1 A;  3G4F A;  5A0J A;  3P5P A;  4LIX A;  3M01 A;  4LA5 A;  4P0X A;  1HX9 A;  4FP4 A;  1VG2 A;  1HXC A;  4OMH A;  5KSX F;  4JZB A;  4KPJ A;  5A0K A;  5ILI A;  4LLS A;  5DIQ F;  4NG6 A;  3WEH A;  5DGN F;  2ZCS A;  3SDR A;  5C05 A;  4WK5 A;  3LSN A;  5IMI A;  4OKZ A;  4LFG A;  3W7F A;  5H9D A;  3ASX A;  1N20 A;  3AQC B;  4DI5 A;  1N21 A;  3RYW A;  3V1X A;  1RQI A;  1HM4 A;  2Q58 A;  3LEE A;  4KPD A;  5JV0 F;  3N3D A;  4EA0 A;  5DGS F;  5DJR F;  3TFP A;  3EZ3 A;  5B0M A;  2Q80 A;  3VJC A;  3N5J F;  3KRC A;  3LZ9 A;  3M9U A;  4LA6 A;  5ERN A;  2OPN A;  3WCI A;  4KK2 A;  2E8W A;  3KRO B;  3WCA A;  3BNX A;  3VJD A;  3AQB B;  3Q1O A;  3TS7 A;  2F9K F;  1N1B A;  4RXD A;  1KIY A;  4EA1 A; 
#chains in the Genus database with same CATH topology
 3LDW A;  2P1C A;  3QKC A;  1WL1 A;  3DYG A;  1HXA A;  3LGK A;  5HN9 A;  3WCB A;  4DWB A;  4MC0 A;  1HXG A;  2VF6 A;  5B0K A;  4K10 A;  3DYF A;  3ICN A;  4JXY A;  3ZMB A;  4NFJ F;  5IKA A;  2OA6 A;  1V4I A;  4LXW A;  4ZQ8 A;  1WL2 A;  2AZK A;  3WCD A;  4LTV A;  1YYT A;  3WC9 A;  1YYS A;  5IKH A;  4GAX A;  4QXS F;  5IL8 A;  3WCG A;  3KRP B;  4OMG A;  5E8L A;  2F8Z F;  3ZCD A;  2PS4 A;  3LK5 A;  3KRO A;  5AYP A;  2F89 F;  3N45 F;  3PKO A;  3SAE A;  4KQ5 A;  4E1E A;  1YHM A;  3ACW A;  5ER8 A;  3ADZ A;  1YYU A;  4UMJ A;  2Z4V A;  4L2X F;  3RBM A;  5B0J A;  2AZL A;  2ONG A;  1WKZ A;  4OGU A;  2E92 A;  4KVY A;  4QPF A;  2OPM A;  1V4H A;  3WJK A;  5A0I A;  4LFE A;  2PS5 A;  3LJI A;  3KB9 A;  3N6K F;  3ICK A;  3RYE A;  3S9V A;  4EA2 A;  4KUX A;  4H5D F;  4Q23 A;  4KWD A;  4NUA A;  5IMP A;  2Z7I A;  3N0F A;  3N3L F;  4RXC A;  4PVY F;  3P5R A;  3KRP A;  3WCJ A;  2F7M F;  5AHU B;  3NRI A;  3ACY A;  4OKM A;  4KVW A;  1EZF A;  3KRA B;  5B0I A;  4F62 A;  3M0G A;  4LZ0 A;  3NF2 A;  1N24 A;  3WEG A;  1UBW A;  4XQS F;  3RMG A;  3TFN A;  1YYQ A;  4KVD A;  4DHD A;  1WL0 A;  1N23 A;  2J5C A;  2J1P A;  2FTZ A;  1JFA A;  5IVG A;  5AEL A;  4DXJ A;  3TFV A;  1VG7 A;  2RAH A;  4GP1 A;  2E91 A;  1WY0 A;  3OAC B;  2F94 F;  2F92 F;  4RXA A;  3PYB A;  1VG3 A;  5E8H A;  3VJB A;  2F8C F;  2ZCQ A;  3M00 A;  5I1U A;  2Z4Z A;  5DGM F;  5JUZ F;  2E93 A;  5B00 A;  3KRA A;  5AFX A;  4E9Z A;  3BNY A;  5HN7 A;  4RNQ A;  5IL3 A;  2H8O A;  3KRF B;  1V4J A;  5B01 A;  3WEJ A;  1KIZ A;  4XQR F;  3V1V A;  3IPI A;  3WE9 A;  4P0V A;  3NPR A;  4LLT A;  2I19 A;  1UBY A;  5DHI A;  4LUU A;  3ZOU A;  2E8T A;  3MAV A;  3LGZ B;  3ID0 A;  2AEK A;  2E8U A;  3EGT A;  3N5H F;  1DGP A;  2EWG A;  3VJ9 A;  5IK6 A;  3WEK A;  4LZ3 A;  5DJV F;  2ONH A;  1V4K A;  2ZY1 A;  1V4E A;  2Q9Y A;  2PS7 A;  2ZCO A;  5HN8 A;  4NFI F;  2J1O A;  5JV2 F;  2Z7H A;  5IK9 A;  5ERO A;  5ILD A;  5DW7 A;  3KRF A;  5DJP F;  4LOB A;  2ZEU A;  3LOM A;  1ZW5 A;  3AE0 A;  3SDV A;  3MZV A;  4KFA A;  3VJE A;  4MC3 A;  5CG6 A;  2AET A;  3UCA A;  4F6V A;  2E4O A;  3ICZ A;  1WL3 A;  2E94 A;  3WEF A;  3N1V F;  2AEL A;  2Z4X A;  5JA0 F;  3APZ A;  4GP2 A;  2E8V A;  3NPK A;  3WCL A;  5DHK A;  1YJ4 A;  1UBV A;  4DEM F;  4PVX F;  3WEI A;  2Q9Z A;  3CP6 A;  5ILZ A;  5EAT A;  3OAB B;  4NKE A;  2ZCR A;  3TC1 A;  1FPS A;  4FJQ A;  1N22 A;  3ICM A;  3SDT A;  3LLW A;  5B03 A;  3WCF A;  3N46 F;  5B0L A;  4DZW A;  3EFQ A;  3WJN A;  3PDE A;  4LPH F;  1HM7 A;  5B02 A;  4JXN A;  3Q30 A;  5E8K A;  1RTR A;  5DZ2 A;  2DH4 A;  3PH7 A;  4F6X A;  1VG6 A;  5IMN A;  1YV5 A;  4DWG A;  3ZL6 A;  3M02 A;  4JYX A;  4NKF A;  2FOR A;  3ACX A;  3P8L A;  1PS1 A;  3DYH A;  3OAB A;  4N9U A;  5IM1 A;  4LTZ A;  3B7L A;  3CC9 A;  3ZMC A;  1WMW A;  3P8R A;  4NFK F;  2OGD A;  1YQ7 A;  3WJO A;  3AQ0 A;  3LVS A;  2O1O A;  4KKM A;  2E90 A;  3Q2Q A;  1RQJ A;  2Z50 A;  3LMD A;  3KBK A;  3OAC A;  1YHK A;  1YHL A;  3SDU A;  5IN8 A;  1JFG A;  2Z52 A;  4XQT F;  3SDQ A;  3WSB A;  4H5C F;  2QIS A;  2E95 A;  5JV1 F;  4KQS A;  3WCC A;  3P41 A;  4GA3 A;  2PS8 A;  2ZEV A;  3LG5 A;  3PYA A;  3N0G A;  1UBX A;  2E8X A;  3QQV A;  4MC8 A;  5CG5 A;  1DI1 A;  3VJ8 A;  5ILJ A;  4RXE A;  5ILY A;  3Q2Z A;  2Z78 A;  3N1W F;  5HNA A;  5ERM A;  4JZX A;  5EAU A;  2Z4W A;  4JVJ F;  1N1Z A;  1VG4 A;  3CKE A;  4RYP A;  3WCH A;  5ILH A;  3IBA A;  3N49 F;  5IK0 A;  4KQU A;  4LFV F;  4LZC A;  4P0W A;  4LPG F;  4KVI A;  4N1Z F;  1YYR A;  3WCE A;  3WSA A;  2AZJ A;  2PS6 A;  3V66 A;  4H5E F;  4E9U A;  5ILK A;  3OYR A;  3S4J A;  3G4D A;  2Z4Y A;  5EAS A;  3VJA A;  3WCM A;  3KRC B;  4HD1 A;  3G4F A;  5A0J A;  3P5P A;  4LIX A;  3M01 A;  4LA5 A;  4P0X A;  1HX9 A;  4FP4 A;  1VG2 A;  1HXC A;  4OMH A;  5KSX F;  4JZB A;  4KPJ A;  5A0K A;  5ILI A;  4LLS A;  5DIQ F;  4NG6 A;  3WEH A;  5DGN F;  2ZCS A;  3SDR A;  5C05 A;  4WK5 A;  3LSN A;  5IMI A;  4OKZ A;  4LFG A;  3W7F A;  5H9D A;  3ASX A;  1N20 A;  3AQC B;  4DI5 A;  1N21 A;  3RYW A;  3V1X A;  1RQI A;  1HM4 A;  2Q58 A;  3LEE A;  4KPD A;  5JV0 F;  3N3D A;  4EA0 A;  5DGS F;  5DJR F;  3TFP A;  3EZ3 A;  5B0M A;  2Q80 A;  3VJC A;  3N5J F;  3KRC A;  3LZ9 A;  3M9U A;  4LA6 A;  5ERN A;  2OPN A;  3WCI A;  4KK2 A;  2E8W A;  3KRO B;  3WCA A;  3BNX A;  3VJD A;  3AQB B;  3Q1O A;  3TS7 A;  2F9K F;  1N1B A;  4RXD A;  1KIY A;  4EA1 A; 
#chains in the Genus database with same CATH homology
 3LDW A;  2P1C A;  3QKC A;  1WL1 A;  3DYG A;  1HXA A;  3LGK A;  5HN9 A;  3WCB A;  4DWB A;  4MC0 A;  1HXG A;  2VF6 A;  5B0K A;  4K10 A;  3DYF A;  3ICN A;  4JXY A;  3ZMB A;  4NFJ F;  5IKA A;  2OA6 A;  1V4I A;  4LXW A;  4ZQ8 A;  1WL2 A;  2AZK A;  3WCD A;  4LTV A;  1YYT A;  3WC9 A;  1YYS A;  5IKH A;  4GAX A;  4QXS F;  5IL8 A;  3WCG A;  3KRP B;  4OMG A;  5E8L A;  2F8Z F;  3ZCD A;  2PS4 A;  3LK5 A;  3KRO A;  5AYP A;  2F89 F;  3N45 F;  3PKO A;  3SAE A;  4KQ5 A;  4E1E A;  1YHM A;  3ACW A;  5ER8 A;  3ADZ A;  1YYU A;  4UMJ A;  2Z4V A;  4L2X F;  3RBM A;  5B0J A;  2AZL A;  2ONG A;  1WKZ A;  4OGU A;  2E92 A;  4KVY A;  4QPF A;  2OPM A;  1V4H A;  3WJK A;  5A0I A;  4LFE A;  2PS5 A;  3LJI A;  3KB9 A;  3N6K F;  3ICK A;  3RYE A;  3S9V A;  4EA2 A;  4KUX A;  4H5D F;  4Q23 A;  4KWD A;  4NUA A;  5IMP A;  2Z7I A;  3N0F A;  3N3L F;  4RXC A;  4PVY F;  3P5R A;  3KRP A;  3WCJ A;  2F7M F;  5AHU B;  3NRI A;  3ACY A;  4OKM A;  4KVW A;  1EZF A;  3KRA B;  5B0I A;  4F62 A;  3M0G A;  4LZ0 A;  3NF2 A;  1N24 A;  3WEG A;  1UBW A;  4XQS F;  3RMG A;  3TFN A;  1YYQ A;  4KVD A;  4DHD A;  1WL0 A;  1N23 A;  2J5C A;  2J1P A;  2FTZ A;  1JFA A;  5IVG A;  5AEL A;  4DXJ A;  3TFV A;  1VG7 A;  2RAH A;  4GP1 A;  2E91 A;  1WY0 A;  3OAC B;  2F94 F;  2F92 F;  4RXA A;  3PYB A;  1VG3 A;  5E8H A;  3VJB A;  2F8C F;  2ZCQ A;  3M00 A;  5I1U A;  2Z4Z A;  5DGM F;  5JUZ F;  2E93 A;  5B00 A;  3KRA A;  5AFX A;  4E9Z A;  3BNY A;  5HN7 A;  4RNQ A;  5IL3 A;  2H8O A;  3KRF B;  1V4J A;  5B01 A;  3WEJ A;  1KIZ A;  4XQR F;  3V1V A;  3IPI A;  3WE9 A;  4P0V A;  3NPR A;  4LLT A;  2I19 A;  1UBY A;  5DHI A;  4LUU A;  3ZOU A;  2E8T A;  3MAV A;  3LGZ B;  3ID0 A;  2AEK A;  2E8U A;  3EGT A;  3N5H F;  1DGP A;  2EWG A;  3VJ9 A;  5IK6 A;  3WEK A;  4LZ3 A;  5DJV F;  2ONH A;  1V4K A;  2ZY1 A;  1V4E A;  2Q9Y A;  2PS7 A;  2ZCO A;  5HN8 A;  4NFI F;  2J1O A;  5JV2 F;  2Z7H A;  5IK9 A;  5ERO A;  5ILD A;  5DW7 A;  3KRF A;  5DJP F;  4LOB A;  2ZEU A;  3LOM A;  1ZW5 A;  3AE0 A;  3SDV A;  3MZV A;  4KFA A;  3VJE A;  4MC3 A;  5CG6 A;  2AET A;  3UCA A;  4F6V A;  2E4O A;  3ICZ A;  1WL3 A;  2E94 A;  3WEF A;  3N1V F;  2AEL A;  2Z4X A;  5JA0 F;  3APZ A;  4GP2 A;  2E8V A;  3NPK A;  3WCL A;  5DHK A;  1YJ4 A;  1UBV A;  4DEM F;  4PVX F;  3WEI A;  2Q9Z A;  3CP6 A;  5ILZ A;  5EAT A;  3OAB B;  4NKE A;  2ZCR A;  3TC1 A;  1FPS A;  4FJQ A;  1N22 A;  3ICM A;  3SDT A;  3LLW A;  5B03 A;  3WCF A;  3N46 F;  5B0L A;  4DZW A;  3EFQ A;  3WJN A;  3PDE A;  4LPH F;  1HM7 A;  5B02 A;  4JXN A;  3Q30 A;  5E8K A;  1RTR A;  5DZ2 A;  2DH4 A;  3PH7 A;  4F6X A;  1VG6 A;  5IMN A;  1YV5 A;  4DWG A;  3ZL6 A;  3M02 A;  4JYX A;  4NKF A;  2FOR A;  3ACX A;  3P8L A;  1PS1 A;  3DYH A;  3OAB A;  4N9U A;  5IM1 A;  4LTZ A;  3B7L A;  3CC9 A;  3ZMC A;  1WMW A;  3P8R A;  4NFK F;  2OGD A;  1YQ7 A;  3WJO A;  3AQ0 A;  3LVS A;  2O1O A;  4KKM A;  2E90 A;  3Q2Q A;  1RQJ A;  2Z50 A;  3LMD A;  3KBK A;  3OAC A;  1YHK A;  1YHL A;  3SDU A;  5IN8 A;  1JFG A;  2Z52 A;  4XQT F;  3SDQ A;  3WSB A;  4H5C F;  2QIS A;  2E95 A;  5JV1 F;  4KQS A;  3WCC A;  3P41 A;  4GA3 A;  2PS8 A;  2ZEV A;  3LG5 A;  3PYA A;  3N0G A;  1UBX A;  2E8X A;  3QQV A;  4MC8 A;  5CG5 A;  1DI1 A;  3VJ8 A;  5ILJ A;  4RXE A;  5ILY A;  3Q2Z A;  2Z78 A;  3N1W F;  5HNA A;  5ERM A;  4JZX A;  5EAU A;  2Z4W A;  4JVJ F;  1N1Z A;  1VG4 A;  3CKE A;  4RYP A;  3WCH A;  5ILH A;  3IBA A;  3N49 F;  5IK0 A;  4KQU A;  4LFV F;  4LZC A;  4P0W A;  4LPG F;  4KVI A;  4N1Z F;  1YYR A;  3WCE A;  3WSA A;  2AZJ A;  2PS6 A;  3V66 A;  4H5E F;  4E9U A;  5ILK A;  3OYR A;  3S4J A;  3G4D A;  2Z4Y A;  5EAS A;  3VJA A;  3WCM A;  3KRC B;  4HD1 A;  3G4F A;  5A0J A;  3P5P A;  4LIX A;  3M01 A;  4LA5 A;  4P0X A;  1HX9 A;  4FP4 A;  1VG2 A;  1HXC A;  4OMH A;  5KSX F;  4JZB A;  4KPJ A;  5A0K A;  5ILI A;  4LLS A;  5DIQ F;  4NG6 A;  3WEH A;  5DGN F;  2ZCS A;  3SDR A;  5C05 A;  4WK5 A;  3LSN A;  5IMI A;  4OKZ A;  4LFG A;  3W7F A;  5H9D A;  3ASX A;  1N20 A;  3AQC B;  4DI5 A;  1N21 A;  3RYW A;  3V1X A;  1RQI A;  1HM4 A;  2Q58 A;  3LEE A;  4KPD A;  5JV0 F;  3N3D A;  4EA0 A;  5DGS F;  5DJR F;  3TFP A;  3EZ3 A;  5B0M A;  2Q80 A;  3VJC A;  3N5J F;  3KRC A;  3LZ9 A;  3M9U A;  4LA6 A;  5ERN A;  2OPN A;  3WCI A;  4KK2 A;  2E8W A;  3KRO B;  3WCA A;  3BNX A;  3VJD A;  3AQB B;  3Q1O A;  3TS7 A;  2F9K F;  1N1B A;  4RXD A;  1KIY A;  4EA1 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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