5CG6A

Neutron crystal structure of human farnesyl pyrophosphate synthase in complex with risedronate and isopentenyl pyrophosphate
Total Genus 138
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
138
sequence length
343
structure length
343
Chain Sequence
DVYAQEKQDFVQHFSQIVRVLTEDEMGHPEIGDAIARLKEVLEYNAIGGKYNRGLTVVVAFRELVEPRKQDADSLQRAWTVGWCVELLQAFFLVADDIMDSSLTRRGQICWYQKPGVGLDAINDANLLEACIYRLLKLYCREQPYYLNLIELFLQSSYQTEIGQTLDLLTAPQGNVDLVRFTEKRYKSIVKYKTAFYSFYLPIAAAMYMAGIDGEKEHANAKKILLEMGEFFQIQDDYLDLFGDPSVTGKIGTDIQDNKCSWLVVQCLQRATPEQYQILKENYGQKEAEKVARVKALYEELDLPAVFLQYEEDSYSHIMALIEQYAAPLPPAVFLGLARKIYK
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Protonation State and Hydration of Bisphosphonate Bound to Farnesyl Pyrophosphate Synthase
pubmed doi rcsb
molecule tags Transferase/transferase inhibitor
source organism Homo sapiens
molecule keywords Farnesyl pyrophosphate synthase
total genus 138
structure length 343
sequence length 343
ec nomenclature ec 2.5.1.1: Dimethylallyltranstransferase.
pdb deposition date 2015-07-09

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00348 polyprenyl_synt Polyprenyl synthetase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.600.10 Mainly Alpha Orthogonal Bundle Farnesyl Diphosphate Synthase Farnesyl Diphosphate Synthase 5cg6A00
1HXAA 2AETA 3RMGA 3ACWA 3N49F 3KRAA 4F6VA 2E8XA 3ZL6A 4KPDA 3N0GA 3PKOA 4RXCA 4NFKF 3QKCA 3WE9A 3TC1A 5JV1F 2RAHA 3WEFA 1YYQA 3WC9A 3KRCB 3OACB 3RYWA 3S4JA 5I1UA 2PS4A 3ACYA 1N24A 3OACA 3WJKA 3WCLA 3APZA 4RXAA 1V4KA 2E8VA 5B03A 2E93A 3B7LA 5ER8A 3WJNA 1YJ4A 5DGMF 3LZ9A 5ILHA 1N20A 4KVWA 5KSXF 4EA0A 4H5DF 5B02A 4EA2A 4MC0A 3EZ3A 2AZLA 5ILIA 4H5EF 1WL1A 5IVGA 4LLSA 3ICZA 4H5CF 3AQ0A 4GA3A 1VG7A 4KQSA 2J1OA 5CG5A 1V4JA 3KRPA 2FTZA 4PVXF 5DZ2A 1KIZA 2E91A 5AYPA 4GP2A 3LEEA 2AEKA 5ERMA 3MZVA 5IM1A 1DI1A 1HXGA 4OMGA 3TFPA 5IKHA 4KWDA 5IL8A 2OPMA 4HD1A 4QPFA 4NFJF 4NUAA 1YYTA 3AE0A 2ZCQA 5JA0F 4PVYF 2Q80A 2Q58A 1VG6A 5HN8A 2ZCSA 1WMWA 3LK5A 2VF6A 4Q23A 1PS1A 2F8ZF 4LPGF 2F92F 5EROA 3P41A 3KROA 5DHKA 5DJPF 1N23A 2ONHA 3WEJA 1WKZA 3IBAA 3Q30A 4RXEA 1YQ7A 4FJQA 2J5CA 5E8LA 3LOMA 4NG6A 3RYEA 3OABB 4ZQ8A 2Z4YA 4LFEA 5IK9A 2ZEUA 5ILYA 3OABA 1VG2A 3KRAB 4KVIA 3WCAA 1UBYA 3N3LF 4F6XA 3ZMBA 3RBMA 3Q2QA 3M00A 2F89F 5E8KA 3LJIA 1FPSA 3SAEA 2E8TA 4RNQA 3IPIA 4N1ZF 1HXCA 5B01A 1VG3A 3P5PA 3W7FA 4F62A 2P1CA 2Z4ZA 5DW7A 5DHIA 3SDVA 2Z4VA 1UBWA 3N6KF 3DYFA 3MAVA 1WL3A 4OGUA 1HM4A 3LVSA 5HN7A 5C05A 5JV0F 5EATA 3DYGA 5A0KA 3VJCA 3N5HF 2Q9YA 3AQCB 5ILZA 1YHKA 4LOBA 1WY0A 3KBKA 3ADZA 2E8UA 5HN9A 3Q2ZA 3KB9A 4DZWA 3TS7A 5ILKA 5IK6A 5HNAA 3ASXA 3SDQA 4JZBA 3LDWA 3ICNA 4DXJA 3ICMA 3N3DA 1YV5A 5DJRF 3P8RA 3KRPB 2E95A 2OPNA 5IK0A 3S9VA 5B0IA 5B0LA 3TFNA 2EWGA 5B0MA 4DWGA 5ERNA 3OYRA 3ID0A 2O1OA 4LA5A 2Q9ZA 5IL3A 2OGDA 3EGTA 1HX9A 3N1WF 1N1BA 5A0IA 4RXDA 3VJDA 1EZFA 3ACXA 1WL0A 3WEKA 3VJEA 5A0JA 2F7MF 2E8WA 3WCDA 3DYHA 3SDRA 3NPRA 2AELA 3PYBA 4E1EA 5B0KA 2Z4WA 3N5JF 1UBVA 1N22A 3M01A 3WCFA 3N0FA 3WCGA 2OA6A 5ILDA 3KROB 4JXYA 5JUZF 2Z52A 1N1ZA 3P8LA 5B00A 4EA1A 4LLTA 3N45F 2DH4A 4KQUA 4LFGA 3NPKA 4KK2A 4KVYA 1UBXA 4LZCA 3WCIA 3WJOA 5EASA 1KIYA 2F8CF 1YHMA 2ZY1A 1N21A 3CC9A 4GP1A 4XQSF 4LPHF 4LXWA 3LMDA 4KKMA 4KVDA 4JYXA 4KPJA 4GAXA 4DHDA 1HM7A 3LGKA 4KQ5A 3M9UA 3VJ9A 5B0JA 1ZW5A 5AELA 3WEIA 5H9DA 2E4OA 3KRFA 3BNYA 4KFAA 5E8HA 4KUXA 3NRIA 3V66A 3VJBA 4JXNA 4LZ3A 4E9ZA 2E90A 3V1XA 4RYPA 3SDTA 2J1PA 4DEMF 3M02A 3ZMCA 5CG6A 2ZCOA 5IN8A 4OKZA 3Q1OA 5DGNF 4P0XA 3LGZB 5AHUB 4P0VA 4LUUA 4WK5A 4E9UA 2ONGA 1JFAA 2E92A 4MC3A 4LZ0A 3EFQA 3WEHA 3KRCA 2Z78A 1V4HA 4P0WA 2Z7IA 3N1VF 5DJVF 1YYRA 3WCCA 3N46F 3TFVA 3G4DA 2E94A 1RTRA 3LLWA 5EAUA 4XQRF 3QQVA 2PS7A 2ZEVA 3WCEA 4MC8A 4NKEA 3WCBA 3UCAA 1V4IA 1JFGA 3WSAA 5IKAA 3WCJA 1DGPA 3VJAA 3WCMA 2AZJA 4N9UA 4JVJF 3PDEA 3V1VA 3ICKA 3G4FA 4K10A 2PS8A 3NF2A 4L2XF 1WL2A 4LFVF 2I19A 3VJ8A 3LG5A 4XQTF 1RQJA 2Z50A 5DGSF 1V4EA 2FORA 3LSNA 3ZCDA 3ZOUA 4QXSF 1RQIA 3WEGA 2AZKA 3WSBA 2Z7HA 2ZCRA 3CP6A 5DIQF 1VG4A 4OKMA 2Z4XA 4UMJA 5IMNA 2PS5A 4LTVA 4NFIF 4OMHA 4DWBA 4JZXA 3AQBB 3BNXA 5IMPA 3P5RA 4NKFA 5ILJA 3M0GA 2F94F 3CKEA 4LIXA 3PYAA 5AFXA 2PS6A 2F9KF 3PH7A 3WCHA 1YHLA 2QISA 5IMIA 1YYSA 1YYUA 3SDUA 4DI5A 4FP4A 2H8OA 3KRFB 4LTZA 4LA6A 5JV2F
chains in the Genus database with same CATH superfamily
1HXAA 2AETA 3RMGA 3ACWA 3N49F 3KRAA 4F6VA 2E8XA 3ZL6A 4KPDA 3N0GA 3PKOA 4RXCA 4NFKF 3QKCA 3WE9A 3TC1A 5JV1F 2RAHA 3WEFA 1YYQA 3WC9A 3KRCB 3OACB 3RYWA 3S4JA 5I1UA 2PS4A 3ACYA 1N24A 3OACA 3WJKA 3WCLA 3APZA 4RXAA 1V4KA 2E8VA 5B03A 2E93A 3B7LA 5ER8A 3WJNA 1YJ4A 5DGMF 3LZ9A 5ILHA 1N20A 4KVWA 5KSXF 4EA0A 4H5DF 5B02A 4EA2A 4MC0A 3EZ3A 2AZLA 5ILIA 4H5EF 1WL1A 5IVGA 4LLSA 3ICZA 4H5CF 3AQ0A 4GA3A 1VG7A 4KQSA 2J1OA 5CG5A 1V4JA 3KRPA 2FTZA 4PVXF 5DZ2A 1KIZA 2E91A 5AYPA 4GP2A 3LEEA 2AEKA 5ERMA 3MZVA 5IM1A 1DI1A 1HXGA 4OMGA 3TFPA 5IKHA 4KWDA 5IL8A 2OPMA 4HD1A 4QPFA 4NFJF 4NUAA 1YYTA 3AE0A 2ZCQA 5JA0F 4PVYF 2Q80A 2Q58A 1VG6A 5HN8A 2ZCSA 1WMWA 3LK5A 2VF6A 4Q23A 1PS1A 2F8ZF 4LPGF 2F92F 5EROA 3P41A 3KROA 5DHKA 5DJPF 1N23A 2ONHA 3WEJA 1WKZA 3IBAA 3Q30A 4RXEA 1YQ7A 4FJQA 2J5CA 5E8LA 3LOMA 4NG6A 3RYEA 3OABB 4ZQ8A 2Z4YA 4LFEA 5IK9A 2ZEUA 5ILYA 3OABA 1VG2A 3KRAB 4KVIA 3WCAA 1UBYA 3N3LF 4F6XA 3ZMBA 3RBMA 3Q2QA 3M00A 2F89F 5E8KA 3LJIA 1FPSA 3SAEA 2E8TA 4RNQA 3IPIA 4N1ZF 1HXCA 5B01A 1VG3A 3P5PA 3W7FA 4F62A 2P1CA 2Z4ZA 5DW7A 5DHIA 3SDVA 2Z4VA 1UBWA 3N6KF 3DYFA 3MAVA 1WL3A 4OGUA 1HM4A 3LVSA 5HN7A 5C05A 5JV0F 5EATA 3DYGA 5A0KA 3VJCA 3N5HF 2Q9YA 3AQCB 5ILZA 1YHKA 4LOBA 1WY0A 3KBKA 3ADZA 2E8UA 5HN9A 3Q2ZA 3KB9A 4DZWA 3TS7A 5ILKA 5IK6A 5HNAA 3ASXA 3SDQA 4JZBA 3LDWA 3ICNA 4DXJA 3ICMA 3N3DA 1YV5A 5DJRF 3P8RA 3KRPB 2E95A 2OPNA 5IK0A 3S9VA 5B0IA 5B0LA 3TFNA 2EWGA 5B0MA 4DWGA 5ERNA 3OYRA 3ID0A 2O1OA 4LA5A 2Q9ZA 5IL3A 2OGDA 3EGTA 1HX9A 3N1WF 1N1BA 5A0IA 4RXDA 3VJDA 1EZFA 3ACXA 1WL0A 3WEKA 3VJEA 5A0JA 2F7MF 2E8WA 3WCDA 3DYHA 3SDRA 3NPRA 2AELA 3PYBA 4E1EA 5B0KA 2Z4WA 3N5JF 1UBVA 1N22A 3M01A 3WCFA 3N0FA 3WCGA 2OA6A 5ILDA 3KROB 4JXYA 5JUZF 2Z52A 1N1ZA 3P8LA 5B00A 4EA1A 4LLTA 3N45F 2DH4A 4KQUA 4LFGA 3NPKA 4KK2A 4KVYA 1UBXA 4LZCA 3WCIA 3WJOA 5EASA 1KIYA 2F8CF 1YHMA 2ZY1A 1N21A 3CC9A 4GP1A 4XQSF 4LPHF 4LXWA 3LMDA 4KKMA 4KVDA 4JYXA 4KPJA 4GAXA 4DHDA 1HM7A 3LGKA 4KQ5A 3M9UA 3VJ9A 5B0JA 1ZW5A 5AELA 3WEIA 5H9DA 2E4OA 3KRFA 3BNYA 4KFAA 5E8HA 4KUXA 3NRIA 3V66A 3VJBA 4JXNA 4LZ3A 4E9ZA 2E90A 3V1XA 4RYPA 3SDTA 2J1PA 4DEMF 3M02A 3ZMCA 5CG6A 2ZCOA 5IN8A 4OKZA 3Q1OA 5DGNF 4P0XA 3LGZB 5AHUB 4P0VA 4LUUA 4WK5A 4E9UA 2ONGA 1JFAA 2E92A 4MC3A 4LZ0A 3EFQA 3WEHA 3KRCA 2Z78A 1V4HA 4P0WA 2Z7IA 3N1VF 5DJVF 1YYRA 3WCCA 3N46F 3TFVA 3G4DA 2E94A 1RTRA 3LLWA 5EAUA 4XQRF 3QQVA 2PS7A 2ZEVA 3WCEA 4MC8A 4NKEA 3WCBA 3UCAA 1V4IA 1JFGA 3WSAA 5IKAA 3WCJA 1DGPA 3VJAA 3WCMA 2AZJA 4N9UA 4JVJF 3PDEA 3V1VA 3ICKA 3G4FA 4K10A 2PS8A 3NF2A 4L2XF 1WL2A 4LFVF 2I19A 3VJ8A 3LG5A 4XQTF 1RQJA 2Z50A 5DGSF 1V4EA 2FORA 3LSNA 3ZCDA 3ZOUA 4QXSF 1RQIA 3WEGA 2AZKA 3WSBA 2Z7HA 2ZCRA 3CP6A 5DIQF 1VG4A 4OKMA 2Z4XA 4UMJA 5IMNA 2PS5A 4LTVA 4NFIF 4OMHA 4DWBA 4JZXA 3AQBB 3BNXA 5IMPA 3P5RA 4NKFA 5ILJA 3M0GA 2F94F 3CKEA 4LIXA 3PYAA 5AFXA 2PS6A 2F9KF 3PH7A 3WCHA 1YHLA 2QISA 5IMIA 1YYSA 1YYUA 3SDUA 4DI5A 4FP4A 2H8OA 3KRFB 4LTZA 4LA6A 5JV2F
chains in the Genus database with same CATH topology
1HXAA 2AETA 3RMGA 3ACWA 3N49F 3KRAA 4F6VA 2E8XA 3ZL6A 4KPDA 3N0GA 3PKOA 4RXCA 4NFKF 3QKCA 3WE9A 3TC1A 5JV1F 2RAHA 3WEFA 1YYQA 3WC9A 3KRCB 3OACB 3RYWA 3S4JA 5I1UA 2PS4A 3ACYA 1N24A 3OACA 3WJKA 3WCLA 3APZA 4RXAA 1V4KA 2E8VA 5B03A 2E93A 3B7LA 5ER8A 3WJNA 1YJ4A 5DGMF 3LZ9A 5ILHA 1N20A 4KVWA 5KSXF 4EA0A 4H5DF 5B02A 4EA2A 4MC0A 3EZ3A 2AZLA 5ILIA 4H5EF 1WL1A 5IVGA 4LLSA 3ICZA 4H5CF 3AQ0A 4GA3A 1VG7A 4KQSA 2J1OA 5CG5A 1V4JA 3KRPA 2FTZA 4PVXF 5DZ2A 1KIZA 2E91A 5AYPA 4GP2A 3LEEA 2AEKA 5ERMA 3MZVA 5IM1A 1DI1A 1HXGA 4OMGA 3TFPA 5IKHA 4KWDA 5IL8A 2OPMA 4HD1A 4QPFA 4NFJF 4NUAA 1YYTA 3AE0A 2ZCQA 5JA0F 4PVYF 2Q80A 2Q58A 1VG6A 5HN8A 2ZCSA 1WMWA 3LK5A 2VF6A 4Q23A 1PS1A 2F8ZF 4LPGF 2F92F 5EROA 3P41A 3KROA 5DHKA 5DJPF 1N23A 2ONHA 3WEJA 1WKZA 3IBAA 3Q30A 4RXEA 1YQ7A 4FJQA 2J5CA 5E8LA 3LOMA 4NG6A 3RYEA 3OABB 4ZQ8A 2Z4YA 4LFEA 5IK9A 2ZEUA 5ILYA 3OABA 1VG2A 3KRAB 4KVIA 3WCAA 1UBYA 3N3LF 4F6XA 3ZMBA 3RBMA 3Q2QA 3M00A 2F89F 5E8KA 3LJIA 1FPSA 3SAEA 2E8TA 4RNQA 3IPIA 4N1ZF 1HXCA 5B01A 1VG3A 3P5PA 3W7FA 4F62A 2P1CA 2Z4ZA 5DW7A 5DHIA 3SDVA 2Z4VA 1UBWA 3N6KF 3DYFA 3MAVA 1WL3A 4OGUA 1HM4A 3LVSA 5HN7A 5C05A 5JV0F 5EATA 3DYGA 5A0KA 3VJCA 3N5HF 2Q9YA 3AQCB 5ILZA 1YHKA 4LOBA 1WY0A 3KBKA 3ADZA 2E8UA 5HN9A 3Q2ZA 3KB9A 4DZWA 3TS7A 5ILKA 5IK6A 5HNAA 3ASXA 3SDQA 4JZBA 3LDWA 3ICNA 4DXJA 3ICMA 3N3DA 1YV5A 5DJRF 3P8RA 3KRPB 2E95A 2OPNA 5IK0A 3S9VA 5B0IA 5B0LA 3TFNA 2EWGA 5B0MA 4DWGA 5ERNA 3OYRA 3ID0A 2O1OA 4LA5A 2Q9ZA 5IL3A 2OGDA 3EGTA 1HX9A 3N1WF 1N1BA 5A0IA 4RXDA 3VJDA 1EZFA 3ACXA 1WL0A 3WEKA 3VJEA 5A0JA 2F7MF 2E8WA 3WCDA 3DYHA 3SDRA 3NPRA 2AELA 3PYBA 4E1EA 5B0KA 2Z4WA 3N5JF 1UBVA 1N22A 3M01A 3WCFA 3N0FA 3WCGA 2OA6A 5ILDA 3KROB 4JXYA 5JUZF 2Z52A 1N1ZA 3P8LA 5B00A 4EA1A 4LLTA 3N45F 2DH4A 4KQUA 4LFGA 3NPKA 4KK2A 4KVYA 1UBXA 4LZCA 3WCIA 3WJOA 5EASA 1KIYA 2F8CF 1YHMA 2ZY1A 1N21A 3CC9A 4GP1A 4XQSF 4LPHF 4LXWA 3LMDA 4KKMA 4KVDA 4JYXA 4KPJA 4GAXA 4DHDA 1HM7A 3LGKA 4KQ5A 3M9UA 3VJ9A 5B0JA 1ZW5A 5AELA 3WEIA 5H9DA 2E4OA 3KRFA 3BNYA 4KFAA 5E8HA 4KUXA 3NRIA 3V66A 3VJBA 4JXNA 4LZ3A 4E9ZA 2E90A 3V1XA 4RYPA 3SDTA 2J1PA 4DEMF 3M02A 3ZMCA 5CG6A 2ZCOA 5IN8A 4OKZA 3Q1OA 5DGNF 4P0XA 3LGZB 5AHUB 4P0VA 4LUUA 4WK5A 4E9UA 2ONGA 1JFAA 2E92A 4MC3A 4LZ0A 3EFQA 3WEHA 3KRCA 2Z78A 1V4HA 4P0WA 2Z7IA 3N1VF 5DJVF 1YYRA 3WCCA 3N46F 3TFVA 3G4DA 2E94A 1RTRA 3LLWA 5EAUA 4XQRF 3QQVA 2PS7A 2ZEVA 3WCEA 4MC8A 4NKEA 3WCBA 3UCAA 1V4IA 1JFGA 3WSAA 5IKAA 3WCJA 1DGPA 3VJAA 3WCMA 2AZJA 4N9UA 4JVJF 3PDEA 3V1VA 3ICKA 3G4FA 4K10A 2PS8A 3NF2A 4L2XF 1WL2A 4LFVF 2I19A 3VJ8A 3LG5A 4XQTF 1RQJA 2Z50A 5DGSF 1V4EA 2FORA 3LSNA 3ZCDA 3ZOUA 4QXSF 1RQIA 3WEGA 2AZKA 3WSBA 2Z7HA 2ZCRA 3CP6A 5DIQF 1VG4A 4OKMA 2Z4XA 4UMJA 5IMNA 2PS5A 4LTVA 4NFIF 4OMHA 4DWBA 4JZXA 3AQBB 3BNXA 5IMPA 3P5RA 4NKFA 5ILJA 3M0GA 2F94F 3CKEA 4LIXA 3PYAA 5AFXA 2PS6A 2F9KF 3PH7A 3WCHA 1YHLA 2QISA 5IMIA 1YYSA 1YYUA 3SDUA 4DI5A 4FP4A 2H8OA 3KRFB 4LTZA 4LA6A 5JV2F
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1HXA A;  2AET A;  3RMG A;  3ACW A;  3N49 F;  3KRA A;  4F6V A;  2E8X A;  3ZL6 A;  4KPD A;  3N0G A;  3PKO A;  4RXC A;  4NFK F;  3QKC A;  3WE9 A;  3TC1 A;  5JV1 F;  2RAH A;  3WEF A;  1YYQ A;  3WC9 A;  3KRC B;  3OAC B;  3RYW A;  3S4J A;  5I1U A;  2PS4 A;  3ACY A;  1N24 A;  3OAC A;  3WJK A;  3WCL A;  3APZ A;  4RXA A;  1V4K A;  2E8V A;  5B03 A;  2E93 A;  3B7L A;  5ER8 A;  3WJN A;  1YJ4 A;  5DGM F;  3LZ9 A;  5ILH A;  1N20 A;  4KVW A;  5KSX F;  4EA0 A;  4H5D F;  5B02 A;  4EA2 A;  4MC0 A;  3EZ3 A;  2AZL A;  5ILI A;  4H5E F;  1WL1 A;  5IVG A;  4LLS A;  3ICZ A;  4H5C F;  3AQ0 A;  4GA3 A;  1VG7 A;  4KQS A;  2J1O A;  5CG5 A;  1V4J A;  3KRP A;  2FTZ A;  4PVX F;  5DZ2 A;  1KIZ A;  2E91 A;  5AYP A;  4GP2 A;  3LEE A;  2AEK A;  5ERM A;  3MZV A;  5IM1 A;  1DI1 A;  1HXG A;  4OMG A;  3TFP A;  5IKH A;  4KWD A;  5IL8 A;  2OPM A;  4HD1 A;  4QPF A;  4NFJ F;  4NUA A;  1YYT A;  3AE0 A;  2ZCQ A;  5JA0 F;  4PVY F;  2Q80 A;  2Q58 A;  1VG6 A;  5HN8 A;  2ZCS A;  1WMW A;  3LK5 A;  2VF6 A;  4Q23 A;  1PS1 A;  2F8Z F;  4LPG F;  2F92 F;  5ERO A;  3P41 A;  3KRO A;  5DHK A;  5DJP F;  1N23 A;  2ONH A;  3WEJ A;  1WKZ A;  3IBA A;  3Q30 A;  4RXE A;  1YQ7 A;  4FJQ A;  2J5C A;  5E8L A;  3LOM A;  4NG6 A;  3RYE A;  3OAB B;  4ZQ8 A;  2Z4Y A;  4LFE A;  5IK9 A;  2ZEU A;  5ILY A;  3OAB A;  1VG2 A;  3KRA B;  4KVI A;  3WCA A;  1UBY A;  3N3L F;  4F6X A;  3ZMB A;  3RBM A;  3Q2Q A;  3M00 A;  2F89 F;  5E8K A;  3LJI A;  1FPS A;  3SAE A;  2E8T A;  4RNQ A;  3IPI A;  4N1Z F;  1HXC A;  5B01 A;  1VG3 A;  3P5P A;  3W7F A;  4F62 A;  2P1C A;  2Z4Z A;  5DW7 A;  5DHI A;  3SDV A;  2Z4V A;  1UBW A;  3N6K F;  3DYF A;  3MAV A;  1WL3 A;  4OGU A;  1HM4 A;  3LVS A;  5HN7 A;  5C05 A;  5JV0 F;  5EAT A;  3DYG A;  5A0K A;  3VJC A;  3N5H F;  2Q9Y A;  3AQC B;  5ILZ A;  1YHK A;  4LOB A;  1WY0 A;  3KBK A;  3ADZ A;  2E8U A;  5HN9 A;  3Q2Z A;  3KB9 A;  4DZW A;  3TS7 A;  5ILK A;  5IK6 A;  5HNA A;  3ASX A;  3SDQ A;  4JZB A;  3LDW A;  3ICN A;  4DXJ A;  3ICM A;  3N3D A;  1YV5 A;  5DJR F;  3P8R A;  3KRP B;  2E95 A;  2OPN A;  5IK0 A;  3S9V A;  5B0I A;  5B0L A;  3TFN A;  2EWG A;  5B0M A;  4DWG A;  5ERN A;  3OYR A;  3ID0 A;  2O1O A;  4LA5 A;  2Q9Z A;  5IL3 A;  2OGD A;  3EGT A;  1HX9 A;  3N1W F;  1N1B A;  5A0I A;  4RXD A;  3VJD A;  1EZF A;  3ACX A;  1WL0 A;  3WEK A;  3VJE A;  5A0J A;  2F7M F;  2E8W A;  3WCD A;  3DYH A;  3SDR A;  3NPR A;  2AEL A;  3PYB A;  4E1E A;  5B0K A;  2Z4W A;  3N5J F;  1UBV A;  1N22 A;  3M01 A;  3WCF A;  3N0F A;  3WCG A;  2OA6 A;  5ILD A;  3KRO B;  4JXY A;  5JUZ F;  2Z52 A;  1N1Z A;  3P8L A;  5B00 A;  4EA1 A;  4LLT A;  3N45 F;  2DH4 A;  4KQU A;  4LFG A;  3NPK A;  4KK2 A;  4KVY A;  1UBX A;  4LZC A;  3WCI A;  3WJO A;  5EAS A;  1KIY A;  2F8C F;  1YHM A;  2ZY1 A;  1N21 A;  3CC9 A;  4GP1 A;  4XQS F;  4LPH F;  4LXW A;  3LMD A;  4KKM A;  4KVD A;  4JYX A;  4KPJ A;  4GAX A;  4DHD A;  1HM7 A;  3LGK A;  4KQ5 A;  3M9U A;  3VJ9 A;  5B0J A;  1ZW5 A;  5AEL A;  3WEI A;  5H9D A;  2E4O A;  3KRF A;  3BNY A;  4KFA A;  5E8H A;  4KUX A;  3NRI A;  3V66 A;  3VJB A;  4JXN A;  4LZ3 A;  4E9Z A;  2E90 A;  3V1X A;  4RYP A;  3SDT A;  2J1P A;  4DEM F;  3M02 A;  3ZMC A;  5CG6 A;  2ZCO A;  5IN8 A;  4OKZ A;  3Q1O A;  5DGN F;  4P0X A;  3LGZ B;  5AHU B;  4P0V A;  4LUU A;  4WK5 A;  4E9U A;  2ONG A;  1JFA A;  2E92 A;  4MC3 A;  4LZ0 A;  3EFQ A;  3WEH A;  3KRC A;  2Z78 A;  1V4H A;  4P0W A;  2Z7I A;  3N1V F;  5DJV F;  1YYR A;  3WCC A;  3N46 F;  3TFV A;  3G4D A;  2E94 A;  1RTR A;  3LLW A;  5EAU A;  4XQR F;  3QQV A;  2PS7 A;  2ZEV A;  3WCE A;  4MC8 A;  4NKE A;  3WCB A;  3UCA A;  1V4I A;  1JFG A;  3WSA A;  5IKA A;  3WCJ A;  1DGP A;  3VJA A;  3WCM A;  2AZJ A;  4N9U A;  4JVJ F;  3PDE A;  3V1V A;  3ICK A;  3G4F A;  4K10 A;  2PS8 A;  3NF2 A;  4L2X F;  1WL2 A;  4LFV F;  2I19 A;  3VJ8 A;  3LG5 A;  4XQT F;  1RQJ A;  2Z50 A;  5DGS F;  1V4E A;  2FOR A;  3LSN A;  3ZCD A;  3ZOU A;  4QXS F;  1RQI A;  3WEG A;  2AZK A;  3WSB A;  2Z7H A;  2ZCR A;  3CP6 A;  5DIQ F;  1VG4 A;  4OKM A;  2Z4X A;  4UMJ A;  5IMN A;  2PS5 A;  4LTV A;  4NFI F;  4OMH A;  4DWB A;  4JZX A;  3AQB B;  3BNX A;  5IMP A;  3P5R A;  4NKF A;  5ILJ A;  3M0G A;  2F94 F;  3CKE A;  4LIX A;  3PYA A;  5AFX A;  2PS6 A;  2F9K F;  3PH7 A;  3WCH A;  1YHL A;  2QIS A;  5IMI A;  1YYS A;  1YYU A;  3SDU A;  4DI5 A;  4FP4 A;  2H8O A;  3KRF B;  4LTZ A;  4LA6 A;  5JV2 F; 
#chains in the Genus database with same CATH topology
 1HXA A;  2AET A;  3RMG A;  3ACW A;  3N49 F;  3KRA A;  4F6V A;  2E8X A;  3ZL6 A;  4KPD A;  3N0G A;  3PKO A;  4RXC A;  4NFK F;  3QKC A;  3WE9 A;  3TC1 A;  5JV1 F;  2RAH A;  3WEF A;  1YYQ A;  3WC9 A;  3KRC B;  3OAC B;  3RYW A;  3S4J A;  5I1U A;  2PS4 A;  3ACY A;  1N24 A;  3OAC A;  3WJK A;  3WCL A;  3APZ A;  4RXA A;  1V4K A;  2E8V A;  5B03 A;  2E93 A;  3B7L A;  5ER8 A;  3WJN A;  1YJ4 A;  5DGM F;  3LZ9 A;  5ILH A;  1N20 A;  4KVW A;  5KSX F;  4EA0 A;  4H5D F;  5B02 A;  4EA2 A;  4MC0 A;  3EZ3 A;  2AZL A;  5ILI A;  4H5E F;  1WL1 A;  5IVG A;  4LLS A;  3ICZ A;  4H5C F;  3AQ0 A;  4GA3 A;  1VG7 A;  4KQS A;  2J1O A;  5CG5 A;  1V4J A;  3KRP A;  2FTZ A;  4PVX F;  5DZ2 A;  1KIZ A;  2E91 A;  5AYP A;  4GP2 A;  3LEE A;  2AEK A;  5ERM A;  3MZV A;  5IM1 A;  1DI1 A;  1HXG A;  4OMG A;  3TFP A;  5IKH A;  4KWD A;  5IL8 A;  2OPM A;  4HD1 A;  4QPF A;  4NFJ F;  4NUA A;  1YYT A;  3AE0 A;  2ZCQ A;  5JA0 F;  4PVY F;  2Q80 A;  2Q58 A;  1VG6 A;  5HN8 A;  2ZCS A;  1WMW A;  3LK5 A;  2VF6 A;  4Q23 A;  1PS1 A;  2F8Z F;  4LPG F;  2F92 F;  5ERO A;  3P41 A;  3KRO A;  5DHK A;  5DJP F;  1N23 A;  2ONH A;  3WEJ A;  1WKZ A;  3IBA A;  3Q30 A;  4RXE A;  1YQ7 A;  4FJQ A;  2J5C A;  5E8L A;  3LOM A;  4NG6 A;  3RYE A;  3OAB B;  4ZQ8 A;  2Z4Y A;  4LFE A;  5IK9 A;  2ZEU A;  5ILY A;  3OAB A;  1VG2 A;  3KRA B;  4KVI A;  3WCA A;  1UBY A;  3N3L F;  4F6X A;  3ZMB A;  3RBM A;  3Q2Q A;  3M00 A;  2F89 F;  5E8K A;  3LJI A;  1FPS A;  3SAE A;  2E8T A;  4RNQ A;  3IPI A;  4N1Z F;  1HXC A;  5B01 A;  1VG3 A;  3P5P A;  3W7F A;  4F62 A;  2P1C A;  2Z4Z A;  5DW7 A;  5DHI A;  3SDV A;  2Z4V A;  1UBW A;  3N6K F;  3DYF A;  3MAV A;  1WL3 A;  4OGU A;  1HM4 A;  3LVS A;  5HN7 A;  5C05 A;  5JV0 F;  5EAT A;  3DYG A;  5A0K A;  3VJC A;  3N5H F;  2Q9Y A;  3AQC B;  5ILZ A;  1YHK A;  4LOB A;  1WY0 A;  3KBK A;  3ADZ A;  2E8U A;  5HN9 A;  3Q2Z A;  3KB9 A;  4DZW A;  3TS7 A;  5ILK A;  5IK6 A;  5HNA A;  3ASX A;  3SDQ A;  4JZB A;  3LDW A;  3ICN A;  4DXJ A;  3ICM A;  3N3D A;  1YV5 A;  5DJR F;  3P8R A;  3KRP B;  2E95 A;  2OPN A;  5IK0 A;  3S9V A;  5B0I A;  5B0L A;  3TFN A;  2EWG A;  5B0M A;  4DWG A;  5ERN A;  3OYR A;  3ID0 A;  2O1O A;  4LA5 A;  2Q9Z A;  5IL3 A;  2OGD A;  3EGT A;  1HX9 A;  3N1W F;  1N1B A;  5A0I A;  4RXD A;  3VJD A;  1EZF A;  3ACX A;  1WL0 A;  3WEK A;  3VJE A;  5A0J A;  2F7M F;  2E8W A;  3WCD A;  3DYH A;  3SDR A;  3NPR A;  2AEL A;  3PYB A;  4E1E A;  5B0K A;  2Z4W A;  3N5J F;  1UBV A;  1N22 A;  3M01 A;  3WCF A;  3N0F A;  3WCG A;  2OA6 A;  5ILD A;  3KRO B;  4JXY A;  5JUZ F;  2Z52 A;  1N1Z A;  3P8L A;  5B00 A;  4EA1 A;  4LLT A;  3N45 F;  2DH4 A;  4KQU A;  4LFG A;  3NPK A;  4KK2 A;  4KVY A;  1UBX A;  4LZC A;  3WCI A;  3WJO A;  5EAS A;  1KIY A;  2F8C F;  1YHM A;  2ZY1 A;  1N21 A;  3CC9 A;  4GP1 A;  4XQS F;  4LPH F;  4LXW A;  3LMD A;  4KKM A;  4KVD A;  4JYX A;  4KPJ A;  4GAX A;  4DHD A;  1HM7 A;  3LGK A;  4KQ5 A;  3M9U A;  3VJ9 A;  5B0J A;  1ZW5 A;  5AEL A;  3WEI A;  5H9D A;  2E4O A;  3KRF A;  3BNY A;  4KFA A;  5E8H A;  4KUX A;  3NRI A;  3V66 A;  3VJB A;  4JXN A;  4LZ3 A;  4E9Z A;  2E90 A;  3V1X A;  4RYP A;  3SDT A;  2J1P A;  4DEM F;  3M02 A;  3ZMC A;  5CG6 A;  2ZCO A;  5IN8 A;  4OKZ A;  3Q1O A;  5DGN F;  4P0X A;  3LGZ B;  5AHU B;  4P0V A;  4LUU A;  4WK5 A;  4E9U A;  2ONG A;  1JFA A;  2E92 A;  4MC3 A;  4LZ0 A;  3EFQ A;  3WEH A;  3KRC A;  2Z78 A;  1V4H A;  4P0W A;  2Z7I A;  3N1V F;  5DJV F;  1YYR A;  3WCC A;  3N46 F;  3TFV A;  3G4D A;  2E94 A;  1RTR A;  3LLW A;  5EAU A;  4XQR F;  3QQV A;  2PS7 A;  2ZEV A;  3WCE A;  4MC8 A;  4NKE A;  3WCB A;  3UCA A;  1V4I A;  1JFG A;  3WSA A;  5IKA A;  3WCJ A;  1DGP A;  3VJA A;  3WCM A;  2AZJ A;  4N9U A;  4JVJ F;  3PDE A;  3V1V A;  3ICK A;  3G4F A;  4K10 A;  2PS8 A;  3NF2 A;  4L2X F;  1WL2 A;  4LFV F;  2I19 A;  3VJ8 A;  3LG5 A;  4XQT F;  1RQJ A;  2Z50 A;  5DGS F;  1V4E A;  2FOR A;  3LSN A;  3ZCD A;  3ZOU A;  4QXS F;  1RQI A;  3WEG A;  2AZK A;  3WSB A;  2Z7H A;  2ZCR A;  3CP6 A;  5DIQ F;  1VG4 A;  4OKM A;  2Z4X A;  4UMJ A;  5IMN A;  2PS5 A;  4LTV A;  4NFI F;  4OMH A;  4DWB A;  4JZX A;  3AQB B;  3BNX A;  5IMP A;  3P5R A;  4NKF A;  5ILJ A;  3M0G A;  2F94 F;  3CKE A;  4LIX A;  3PYA A;  5AFX A;  2PS6 A;  2F9K F;  3PH7 A;  3WCH A;  1YHL A;  2QIS A;  5IMI A;  1YYS A;  1YYU A;  3SDU A;  4DI5 A;  4FP4 A;  2H8O A;  3KRF B;  4LTZ A;  4LA6 A;  5JV2 F; 
#chains in the Genus database with same CATH homology
 1HXA A;  2AET A;  3RMG A;  3ACW A;  3N49 F;  3KRA A;  4F6V A;  2E8X A;  3ZL6 A;  4KPD A;  3N0G A;  3PKO A;  4RXC A;  4NFK F;  3QKC A;  3WE9 A;  3TC1 A;  5JV1 F;  2RAH A;  3WEF A;  1YYQ A;  3WC9 A;  3KRC B;  3OAC B;  3RYW A;  3S4J A;  5I1U A;  2PS4 A;  3ACY A;  1N24 A;  3OAC A;  3WJK A;  3WCL A;  3APZ A;  4RXA A;  1V4K A;  2E8V A;  5B03 A;  2E93 A;  3B7L A;  5ER8 A;  3WJN A;  1YJ4 A;  5DGM F;  3LZ9 A;  5ILH A;  1N20 A;  4KVW A;  5KSX F;  4EA0 A;  4H5D F;  5B02 A;  4EA2 A;  4MC0 A;  3EZ3 A;  2AZL A;  5ILI A;  4H5E F;  1WL1 A;  5IVG A;  4LLS A;  3ICZ A;  4H5C F;  3AQ0 A;  4GA3 A;  1VG7 A;  4KQS A;  2J1O A;  5CG5 A;  1V4J A;  3KRP A;  2FTZ A;  4PVX F;  5DZ2 A;  1KIZ A;  2E91 A;  5AYP A;  4GP2 A;  3LEE A;  2AEK A;  5ERM A;  3MZV A;  5IM1 A;  1DI1 A;  1HXG A;  4OMG A;  3TFP A;  5IKH A;  4KWD A;  5IL8 A;  2OPM A;  4HD1 A;  4QPF A;  4NFJ F;  4NUA A;  1YYT A;  3AE0 A;  2ZCQ A;  5JA0 F;  4PVY F;  2Q80 A;  2Q58 A;  1VG6 A;  5HN8 A;  2ZCS A;  1WMW A;  3LK5 A;  2VF6 A;  4Q23 A;  1PS1 A;  2F8Z F;  4LPG F;  2F92 F;  5ERO A;  3P41 A;  3KRO A;  5DHK A;  5DJP F;  1N23 A;  2ONH A;  3WEJ A;  1WKZ A;  3IBA A;  3Q30 A;  4RXE A;  1YQ7 A;  4FJQ A;  2J5C A;  5E8L A;  3LOM A;  4NG6 A;  3RYE A;  3OAB B;  4ZQ8 A;  2Z4Y A;  4LFE A;  5IK9 A;  2ZEU A;  5ILY A;  3OAB A;  1VG2 A;  3KRA B;  4KVI A;  3WCA A;  1UBY A;  3N3L F;  4F6X A;  3ZMB A;  3RBM A;  3Q2Q A;  3M00 A;  2F89 F;  5E8K A;  3LJI A;  1FPS A;  3SAE A;  2E8T A;  4RNQ A;  3IPI A;  4N1Z F;  1HXC A;  5B01 A;  1VG3 A;  3P5P A;  3W7F A;  4F62 A;  2P1C A;  2Z4Z A;  5DW7 A;  5DHI A;  3SDV A;  2Z4V A;  1UBW A;  3N6K F;  3DYF A;  3MAV A;  1WL3 A;  4OGU A;  1HM4 A;  3LVS A;  5HN7 A;  5C05 A;  5JV0 F;  5EAT A;  3DYG A;  5A0K A;  3VJC A;  3N5H F;  2Q9Y A;  3AQC B;  5ILZ A;  1YHK A;  4LOB A;  1WY0 A;  3KBK A;  3ADZ A;  2E8U A;  5HN9 A;  3Q2Z A;  3KB9 A;  4DZW A;  3TS7 A;  5ILK A;  5IK6 A;  5HNA A;  3ASX A;  3SDQ A;  4JZB A;  3LDW A;  3ICN A;  4DXJ A;  3ICM A;  3N3D A;  1YV5 A;  5DJR F;  3P8R A;  3KRP B;  2E95 A;  2OPN A;  5IK0 A;  3S9V A;  5B0I A;  5B0L A;  3TFN A;  2EWG A;  5B0M A;  4DWG A;  5ERN A;  3OYR A;  3ID0 A;  2O1O A;  4LA5 A;  2Q9Z A;  5IL3 A;  2OGD A;  3EGT A;  1HX9 A;  3N1W F;  1N1B A;  5A0I A;  4RXD A;  3VJD A;  1EZF A;  3ACX A;  1WL0 A;  3WEK A;  3VJE A;  5A0J A;  2F7M F;  2E8W A;  3WCD A;  3DYH A;  3SDR A;  3NPR A;  2AEL A;  3PYB A;  4E1E A;  5B0K A;  2Z4W A;  3N5J F;  1UBV A;  1N22 A;  3M01 A;  3WCF A;  3N0F A;  3WCG A;  2OA6 A;  5ILD A;  3KRO B;  4JXY A;  5JUZ F;  2Z52 A;  1N1Z A;  3P8L A;  5B00 A;  4EA1 A;  4LLT A;  3N45 F;  2DH4 A;  4KQU A;  4LFG A;  3NPK A;  4KK2 A;  4KVY A;  1UBX A;  4LZC A;  3WCI A;  3WJO A;  5EAS A;  1KIY A;  2F8C F;  1YHM A;  2ZY1 A;  1N21 A;  3CC9 A;  4GP1 A;  4XQS F;  4LPH F;  4LXW A;  3LMD A;  4KKM A;  4KVD A;  4JYX A;  4KPJ A;  4GAX A;  4DHD A;  1HM7 A;  3LGK A;  4KQ5 A;  3M9U A;  3VJ9 A;  5B0J A;  1ZW5 A;  5AEL A;  3WEI A;  5H9D A;  2E4O A;  3KRF A;  3BNY A;  4KFA A;  5E8H A;  4KUX A;  3NRI A;  3V66 A;  3VJB A;  4JXN A;  4LZ3 A;  4E9Z A;  2E90 A;  3V1X A;  4RYP A;  3SDT A;  2J1P A;  4DEM F;  3M02 A;  3ZMC A;  5CG6 A;  2ZCO A;  5IN8 A;  4OKZ A;  3Q1O A;  5DGN F;  4P0X A;  3LGZ B;  5AHU B;  4P0V A;  4LUU A;  4WK5 A;  4E9U A;  2ONG A;  1JFA A;  2E92 A;  4MC3 A;  4LZ0 A;  3EFQ A;  3WEH A;  3KRC A;  2Z78 A;  1V4H A;  4P0W A;  2Z7I A;  3N1V F;  5DJV F;  1YYR A;  3WCC A;  3N46 F;  3TFV A;  3G4D A;  2E94 A;  1RTR A;  3LLW A;  5EAU A;  4XQR F;  3QQV A;  2PS7 A;  2ZEV A;  3WCE A;  4MC8 A;  4NKE A;  3WCB A;  3UCA A;  1V4I A;  1JFG A;  3WSA A;  5IKA A;  3WCJ A;  1DGP A;  3VJA A;  3WCM A;  2AZJ A;  4N9U A;  4JVJ F;  3PDE A;  3V1V A;  3ICK A;  3G4F A;  4K10 A;  2PS8 A;  3NF2 A;  4L2X F;  1WL2 A;  4LFV F;  2I19 A;  3VJ8 A;  3LG5 A;  4XQT F;  1RQJ A;  2Z50 A;  5DGS F;  1V4E A;  2FOR A;  3LSN A;  3ZCD A;  3ZOU A;  4QXS F;  1RQI A;  3WEG A;  2AZK A;  3WSB A;  2Z7H A;  2ZCR A;  3CP6 A;  5DIQ F;  1VG4 A;  4OKM A;  2Z4X A;  4UMJ A;  5IMN A;  2PS5 A;  4LTV A;  4NFI F;  4OMH A;  4DWB A;  4JZX A;  3AQB B;  3BNX A;  5IMP A;  3P5R A;  4NKF A;  5ILJ A;  3M0G A;  2F94 F;  3CKE A;  4LIX A;  3PYA A;  5AFX A;  2PS6 A;  2F9K F;  3PH7 A;  3WCH A;  1YHL A;  2QIS A;  5IMI A;  1YYS A;  1YYU A;  3SDU A;  4DI5 A;  4FP4 A;  2H8O A;  3KRF B;  4LTZ A;  4LA6 A;  5JV2 F; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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