5DIQF

Crystal structure of human fpps in complex with salicylic acid derivative 3a
Total Genus 134
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
134
sequence length
345
structure length
345
Chain Sequence
DVYAQEKQDFVQHFSQIVRVLTEDEMGHPEIGDAIARLKEVLEYNAIGGKYNRGLTVVVAFRELVEPRKQDADSLQRAWTVGWCVELLQAFFLVADDIMDSSLTRRGQICWYQKPGVGLDAINDANLLEACIYRLLKLYCREQPYYLNLIELFLQSSYQTEIGQTLDLLTAPQGNVDLVRFTEKRYKSIVKYKTAFYSFYLPIAAAMYMAGIDGEKEHANAKKILLEMGEFFQIQDDYLDLFGDPSVTGKIGTDIQDNKCSWLVVQCLQRATPEQYQILKENYGQKEAEKVARVKALYEELDLPAVFLQYEEDSYSHIMALIEQYAAPLPPAVFLGLARKIYKRR
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Discovery of Novel Allosteric Non-Bisphosphonate Inhibitors of Farnesyl Pyrophosphate Synthase by Integrated Lead Finding.
pubmed doi rcsb
molecule tags Transferase
source organism Homo sapiens
molecule keywords Farnesyl pyrophosphate synthase
total genus 134
structure length 345
sequence length 345
ec nomenclature ec 2.5.1.1: Dimethylallyltranstransferase.
pdb deposition date 2015-09-01

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
F PF00348 polyprenyl_synt Polyprenyl synthetase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.600.10 Mainly Alpha Orthogonal Bundle Farnesyl Diphosphate Synthase Farnesyl Diphosphate Synthase 5diqF00
2E93A 5HN9A 1N1BA 2E8VA 3N1VF 5JV2F 2OPMA 3WCMA 3G4FA 4LTVA 1HXAA 3LEEA 5IMPA 4LA5A 2F94F 5AFXA 4MC3A 3LVSA 3OABB 4KUXA 3CKEA 3RBMA 2ZY1A 1KIZA 3WJNA 5DJRF 3WCHA 1YHLA 3LDWA 2ZCOA 4JZXA 4E9UA 4ZQ8A 1WL2A 4JYXA 2E8UA 3WCBA 4FP4A 3QKCA 3DYGA 4GP2A 1RTRA 2E8TA 2H8OA 5IVGA 3SAEA 3VJAA 4DWBA 3WCJA 5KSXF 4OMHA 3WSBA 4KWDA 1ZW5A 2Z4YA 3BNYA 3G4DA 3Q2ZA 4LFVF 2AZJA 5AHUB 2Z78A 5DIQF 3VJCA 3WCEA 3N3LF 4NFIF 1VG4A 3Q30A 4RXDA 3ICKA 2F7MF 1YYSA 3TFVA 2PS8A 5DJVF 2J1PA 5H9DA 4LTZA 3ACYA 5DZ2A 5B0LA 4KVIA 4KFAA 4LIXA 2E91A 3WJOA 4NKFA 5A0IA 3WE9A 3V66A 3AQCB 5JA0F 3APZA 4QPFA 3WCLA 3LG5A 2F8ZF 3KRAB 3N5HF 3N49F 5EAUA 2P1CA 4RXEA 3NPKA 3V1VA 4EA0A 2Q80A 2EWGA 5IL8A 1N21A 4OKZA 5IM1A 3N0GA 3DYHA 4FJQA 5ILHA 4H5CF 3KRCA 4LZ3A 5DHIA 3LGKA 1UBVA 4KQSA 1YYRA 2O1OA 3WEGA 3PKOA 3RYEA 3KB9A 4H5DF 3EGTA 5IK0A 5B00A 2AETA 4LFGA 1RQJA 5IN8A 2OGDA 4KVYA 4LUUA 5B0KA 1YHKA 1FPSA 3AQBB 3Q1OA 3VJ8A 5ILYA 4LLTA 3ICNA 3ZL6A 5IMNA 3Q2QA 2AZLA 1UBWA 4F6VA 3LSNA 1YHMA 3PH7A 5B0JA 4P0WA 1EZFA 1WY0A 4NUAA 3KRFA 1VG7A 3QQVA 3WEHA 2I19A 2PS7A 4KQUA 5E8HA 3ZMCA 4E9ZA 4PVXF 4LXWA 3CP6A 5B0MA 3V1XA 4JXNA 3WCCA 2DH4A 4JXYA 4DZWA 5HN7A 5AELA 2ONHA 5HNAA 3N0FA 3ZCDA 3SDRA 4GA3A 3N5JF 3ACWA 4NFJF 3SDUA 1N20A 3UCAA 1DI1A 4XQTF 2E8WA 2RAHA 4EA1A 3N6KF 5IKAA 3KROB 4RYPA 4UMJA 4NKEA 4MC0A 5DHKA 3OABA 2F8CF 5IK6A 1V4EA 3KBKA 4XQSF 5I1UA 4HD1A 4KK2A 4RXCA 1DGPA 4KVWA 3B7LA 3S4JA 4WK5A 1KIYA 4LPGF 3ID0A 5EATA 5JV0F 3ACXA 3W7FA 3WCAA 1V4HA 2Z7HA 1YYUA 2ZCSA 3WCIA 4F62A 4LLSA 4LPHF 3TFNA 2PS4A 1WKZA 2J5CA 3N45F 3WEKA 4DHDA 5DGSF 1VG3A 1N1ZA 5ILZA 2F89F 4GAXA 4OKMA 2F92F 2Q9ZA 3KRAA 3P8RA 3WEJA 3AQ0A 5B01A 3P5RA 3LZ9A 2OPNA 2E8XA 1UBYA 3KRPB 5IL3A 3IPIA 1YYTA 3WC9A 5HN8A 1WL0A 2Q58A 1PS1A 3SDQA 3M02A 3VJDA 2Z4VA 4LOBA 5C05A 5ERNA 3OYRA 3WCDA 3P8LA 3ICZA 3LGZB 3S9VA 5IK9A 1JFGA 2J1OA 5EASA 3BNXA 4JVJF 3ADZA 2VF6A 1N24A 1V4JA 3RYWA 3MZVA 5JV1F 2Z52A 5ILIA 4P0VA 5DW7A 4MC8A 3IBAA 3VJ9A 2AELA 5ERMA 5DGMF 1VG2A 3OACA 5B03A 5A0KA 2E94A 1YYQA 1V4KA 3TC1A 3ZMBA 5ER8A 5CG6A 3EZ3A 2QISA 3WEFA 5B0IA 3M01A 3WJKA 1RQIA 4LZ0A 2OA6A 3M0GA 4DEMF 5CG5A 4RNQA 4RXAA 3WSAA 3VJBA 3WCGA 1YV5A 1WL3A 5ILJA 1YJ4A 4E1EA 3VJEA 5ILDA 3SDTA 2ZEUA 2Z7IA 4EA2A 1HM4A 2E92A 3NRIA 5E8KA 5IMIA 4KQ5A 2E95A 4DWGA 4OGUA 3SDVA 4NFKF 4F6XA 4NG6A 4DI5A 3EFQA 5A0JA 2FTZA 3TFPA 3ICMA 4LA6A 3WCFA 5JUZF 2Z4XA 4N9UA 4XQRF 3N1WF 1HM7A 2AZKA 3ZOUA 2F9KF 1WL1A 3DYFA 4H5EF 3KROA 3WEIA 4K10A 2Z50A 3N3DA 3AE0A 3KRCB 4JZBA 4Q23A 3LOMA 4KVDA 4KPDA 4N1ZF 4PVYF 5AYPA 2E90A 1V4IA 3N46F 3P41A 4DXJA 5E8LA 2ZEVA 4LZCA 3PDEA 2Z4ZA 3LLWA 4QXSF 2ZCRA 5ILKA 1WMWA 1N23A 2ONGA 3PYBA 2E4OA 3CC9A 3MAVA 3M00A 2Q9YA 1HX9A 4KPJA 4L2XF 4LFEA 2ZCQA 1UBXA 3LJIA 3NF2A 3NPRA 2FORA 1JFAA 5EROA 3KRFB 3LMDA 4OMGA 2AEKA 1YQ7A 2Z4WA 4GP1A 2PS5A 1N22A 5DGNF 5IKHA 3ASXA 3OACB 3PYAA 3LK5A 1HXGA 3TS7A 3M9UA 3P5PA 1HXCA 5B02A 4KKMA 3KRPA 1VG6A 2PS6A 4P0XA 5DJPF 3RMGA
chains in the Genus database with same CATH superfamily
2E93A 5HN9A 1N1BA 2E8VA 3N1VF 5JV2F 2OPMA 3WCMA 3G4FA 4LTVA 1HXAA 3LEEA 5IMPA 4LA5A 2F94F 5AFXA 4MC3A 3LVSA 3OABB 4KUXA 3CKEA 3RBMA 2ZY1A 1KIZA 3WJNA 5DJRF 3WCHA 1YHLA 3LDWA 2ZCOA 4JZXA 4E9UA 4ZQ8A 1WL2A 4JYXA 2E8UA 3WCBA 4FP4A 3QKCA 3DYGA 4GP2A 1RTRA 2E8TA 2H8OA 5IVGA 3SAEA 3VJAA 4DWBA 3WCJA 5KSXF 4OMHA 3WSBA 4KWDA 1ZW5A 2Z4YA 3BNYA 3G4DA 3Q2ZA 4LFVF 2AZJA 5AHUB 2Z78A 5DIQF 3VJCA 3WCEA 3N3LF 4NFIF 1VG4A 3Q30A 4RXDA 3ICKA 2F7MF 1YYSA 3TFVA 2PS8A 5DJVF 2J1PA 5H9DA 4LTZA 3ACYA 5DZ2A 5B0LA 4KVIA 4KFAA 4LIXA 2E91A 3WJOA 4NKFA 5A0IA 3WE9A 3V66A 3AQCB 5JA0F 3APZA 4QPFA 3WCLA 3LG5A 2F8ZF 3KRAB 3N5HF 3N49F 5EAUA 2P1CA 4RXEA 3NPKA 3V1VA 4EA0A 2Q80A 2EWGA 5IL8A 1N21A 4OKZA 5IM1A 3N0GA 3DYHA 4FJQA 5ILHA 4H5CF 3KRCA 4LZ3A 5DHIA 3LGKA 1UBVA 4KQSA 1YYRA 2O1OA 3WEGA 3PKOA 3RYEA 3KB9A 4H5DF 3EGTA 5IK0A 5B00A 2AETA 4LFGA 1RQJA 5IN8A 2OGDA 4KVYA 4LUUA 5B0KA 1YHKA 1FPSA 3AQBB 3Q1OA 3VJ8A 5ILYA 4LLTA 3ICNA 3ZL6A 5IMNA 3Q2QA 2AZLA 1UBWA 4F6VA 3LSNA 1YHMA 3PH7A 5B0JA 4P0WA 1EZFA 1WY0A 4NUAA 3KRFA 1VG7A 3QQVA 3WEHA 2I19A 2PS7A 4KQUA 5E8HA 3ZMCA 4E9ZA 4PVXF 4LXWA 3CP6A 5B0MA 3V1XA 4JXNA 3WCCA 2DH4A 4JXYA 4DZWA 5HN7A 5AELA 2ONHA 5HNAA 3N0FA 3ZCDA 3SDRA 4GA3A 3N5JF 3ACWA 4NFJF 3SDUA 1N20A 3UCAA 1DI1A 4XQTF 2E8WA 2RAHA 4EA1A 3N6KF 5IKAA 3KROB 4RYPA 4UMJA 4NKEA 4MC0A 5DHKA 3OABA 2F8CF 5IK6A 1V4EA 3KBKA 4XQSF 5I1UA 4HD1A 4KK2A 4RXCA 1DGPA 4KVWA 3B7LA 3S4JA 4WK5A 1KIYA 4LPGF 3ID0A 5EATA 5JV0F 3ACXA 3W7FA 3WCAA 1V4HA 2Z7HA 1YYUA 2ZCSA 3WCIA 4F62A 4LLSA 4LPHF 3TFNA 2PS4A 1WKZA 2J5CA 3N45F 3WEKA 4DHDA 5DGSF 1VG3A 1N1ZA 5ILZA 2F89F 4GAXA 4OKMA 2F92F 2Q9ZA 3KRAA 3P8RA 3WEJA 3AQ0A 5B01A 3P5RA 3LZ9A 2OPNA 2E8XA 1UBYA 3KRPB 5IL3A 3IPIA 1YYTA 3WC9A 5HN8A 1WL0A 2Q58A 1PS1A 3SDQA 3M02A 3VJDA 2Z4VA 4LOBA 5C05A 5ERNA 3OYRA 3WCDA 3P8LA 3ICZA 3LGZB 3S9VA 5IK9A 1JFGA 2J1OA 5EASA 3BNXA 4JVJF 3ADZA 2VF6A 1N24A 1V4JA 3RYWA 3MZVA 5JV1F 2Z52A 5ILIA 4P0VA 5DW7A 4MC8A 3IBAA 3VJ9A 2AELA 5ERMA 5DGMF 1VG2A 3OACA 5B03A 5A0KA 2E94A 1YYQA 1V4KA 3TC1A 3ZMBA 5ER8A 5CG6A 3EZ3A 2QISA 3WEFA 5B0IA 3M01A 3WJKA 1RQIA 4LZ0A 2OA6A 3M0GA 4DEMF 5CG5A 4RNQA 4RXAA 3WSAA 3VJBA 3WCGA 1YV5A 1WL3A 5ILJA 1YJ4A 4E1EA 3VJEA 5ILDA 3SDTA 2ZEUA 2Z7IA 4EA2A 1HM4A 2E92A 3NRIA 5E8KA 5IMIA 4KQ5A 2E95A 4DWGA 4OGUA 3SDVA 4NFKF 4F6XA 4NG6A 4DI5A 3EFQA 5A0JA 2FTZA 3TFPA 3ICMA 4LA6A 3WCFA 5JUZF 2Z4XA 4N9UA 4XQRF 3N1WF 1HM7A 2AZKA 3ZOUA 2F9KF 1WL1A 3DYFA 4H5EF 3KROA 3WEIA 4K10A 2Z50A 3N3DA 3AE0A 3KRCB 4JZBA 4Q23A 3LOMA 4KVDA 4KPDA 4N1ZF 4PVYF 5AYPA 2E90A 1V4IA 3N46F 3P41A 4DXJA 5E8LA 2ZEVA 4LZCA 3PDEA 2Z4ZA 3LLWA 4QXSF 2ZCRA 5ILKA 1WMWA 1N23A 2ONGA 3PYBA 2E4OA 3CC9A 3MAVA 3M00A 2Q9YA 1HX9A 4KPJA 4L2XF 4LFEA 2ZCQA 1UBXA 3LJIA 3NF2A 3NPRA 2FORA 1JFAA 5EROA 3KRFB 3LMDA 4OMGA 2AEKA 1YQ7A 2Z4WA 4GP1A 2PS5A 1N22A 5DGNF 5IKHA 3ASXA 3OACB 3PYAA 3LK5A 1HXGA 3TS7A 3M9UA 3P5PA 1HXCA 5B02A 4KKMA 3KRPA 1VG6A 2PS6A 4P0XA 5DJPF 3RMGA
chains in the Genus database with same CATH topology
2E93A 5HN9A 1N1BA 2E8VA 3N1VF 5JV2F 2OPMA 3WCMA 3G4FA 4LTVA 1HXAA 3LEEA 5IMPA 4LA5A 2F94F 5AFXA 4MC3A 3LVSA 3OABB 4KUXA 3CKEA 3RBMA 2ZY1A 1KIZA 3WJNA 5DJRF 3WCHA 1YHLA 3LDWA 2ZCOA 4JZXA 4E9UA 4ZQ8A 1WL2A 4JYXA 2E8UA 3WCBA 4FP4A 3QKCA 3DYGA 4GP2A 1RTRA 2E8TA 2H8OA 5IVGA 3SAEA 3VJAA 4DWBA 3WCJA 5KSXF 4OMHA 3WSBA 4KWDA 1ZW5A 2Z4YA 3BNYA 3G4DA 3Q2ZA 4LFVF 2AZJA 5AHUB 2Z78A 5DIQF 3VJCA 3WCEA 3N3LF 4NFIF 1VG4A 3Q30A 4RXDA 3ICKA 2F7MF 1YYSA 3TFVA 2PS8A 5DJVF 2J1PA 5H9DA 4LTZA 3ACYA 5DZ2A 5B0LA 4KVIA 4KFAA 4LIXA 2E91A 3WJOA 4NKFA 5A0IA 3WE9A 3V66A 3AQCB 5JA0F 3APZA 4QPFA 3WCLA 3LG5A 2F8ZF 3KRAB 3N5HF 3N49F 5EAUA 2P1CA 4RXEA 3NPKA 3V1VA 4EA0A 2Q80A 2EWGA 5IL8A 1N21A 4OKZA 5IM1A 3N0GA 3DYHA 4FJQA 5ILHA 4H5CF 3KRCA 4LZ3A 5DHIA 3LGKA 1UBVA 4KQSA 1YYRA 2O1OA 3WEGA 3PKOA 3RYEA 3KB9A 4H5DF 3EGTA 5IK0A 5B00A 2AETA 4LFGA 1RQJA 5IN8A 2OGDA 4KVYA 4LUUA 5B0KA 1YHKA 1FPSA 3AQBB 3Q1OA 3VJ8A 5ILYA 4LLTA 3ICNA 3ZL6A 5IMNA 3Q2QA 2AZLA 1UBWA 4F6VA 3LSNA 1YHMA 3PH7A 5B0JA 4P0WA 1EZFA 1WY0A 4NUAA 3KRFA 1VG7A 3QQVA 3WEHA 2I19A 2PS7A 4KQUA 5E8HA 3ZMCA 4E9ZA 4PVXF 4LXWA 3CP6A 5B0MA 3V1XA 4JXNA 3WCCA 2DH4A 4JXYA 4DZWA 5HN7A 5AELA 2ONHA 5HNAA 3N0FA 3ZCDA 3SDRA 4GA3A 3N5JF 3ACWA 4NFJF 3SDUA 1N20A 3UCAA 1DI1A 4XQTF 2E8WA 2RAHA 4EA1A 3N6KF 5IKAA 3KROB 4RYPA 4UMJA 4NKEA 4MC0A 5DHKA 3OABA 2F8CF 5IK6A 1V4EA 3KBKA 4XQSF 5I1UA 4HD1A 4KK2A 4RXCA 1DGPA 4KVWA 3B7LA 3S4JA 4WK5A 1KIYA 4LPGF 3ID0A 5EATA 5JV0F 3ACXA 3W7FA 3WCAA 1V4HA 2Z7HA 1YYUA 2ZCSA 3WCIA 4F62A 4LLSA 4LPHF 3TFNA 2PS4A 1WKZA 2J5CA 3N45F 3WEKA 4DHDA 5DGSF 1VG3A 1N1ZA 5ILZA 2F89F 4GAXA 4OKMA 2F92F 2Q9ZA 3KRAA 3P8RA 3WEJA 3AQ0A 5B01A 3P5RA 3LZ9A 2OPNA 2E8XA 1UBYA 3KRPB 5IL3A 3IPIA 1YYTA 3WC9A 5HN8A 1WL0A 2Q58A 1PS1A 3SDQA 3M02A 3VJDA 2Z4VA 4LOBA 5C05A 5ERNA 3OYRA 3WCDA 3P8LA 3ICZA 3LGZB 3S9VA 5IK9A 1JFGA 2J1OA 5EASA 3BNXA 4JVJF 3ADZA 2VF6A 1N24A 1V4JA 3RYWA 3MZVA 5JV1F 2Z52A 5ILIA 4P0VA 5DW7A 4MC8A 3IBAA 3VJ9A 2AELA 5ERMA 5DGMF 1VG2A 3OACA 5B03A 5A0KA 2E94A 1YYQA 1V4KA 3TC1A 3ZMBA 5ER8A 5CG6A 3EZ3A 2QISA 3WEFA 5B0IA 3M01A 3WJKA 1RQIA 4LZ0A 2OA6A 3M0GA 4DEMF 5CG5A 4RNQA 4RXAA 3WSAA 3VJBA 3WCGA 1YV5A 1WL3A 5ILJA 1YJ4A 4E1EA 3VJEA 5ILDA 3SDTA 2ZEUA 2Z7IA 4EA2A 1HM4A 2E92A 3NRIA 5E8KA 5IMIA 4KQ5A 2E95A 4DWGA 4OGUA 3SDVA 4NFKF 4F6XA 4NG6A 4DI5A 3EFQA 5A0JA 2FTZA 3TFPA 3ICMA 4LA6A 3WCFA 5JUZF 2Z4XA 4N9UA 4XQRF 3N1WF 1HM7A 2AZKA 3ZOUA 2F9KF 1WL1A 3DYFA 4H5EF 3KROA 3WEIA 4K10A 2Z50A 3N3DA 3AE0A 3KRCB 4JZBA 4Q23A 3LOMA 4KVDA 4KPDA 4N1ZF 4PVYF 5AYPA 2E90A 1V4IA 3N46F 3P41A 4DXJA 5E8LA 2ZEVA 4LZCA 3PDEA 2Z4ZA 3LLWA 4QXSF 2ZCRA 5ILKA 1WMWA 1N23A 2ONGA 3PYBA 2E4OA 3CC9A 3MAVA 3M00A 2Q9YA 1HX9A 4KPJA 4L2XF 4LFEA 2ZCQA 1UBXA 3LJIA 3NF2A 3NPRA 2FORA 1JFAA 5EROA 3KRFB 3LMDA 4OMGA 2AEKA 1YQ7A 2Z4WA 4GP1A 2PS5A 1N22A 5DGNF 5IKHA 3ASXA 3OACB 3PYAA 3LK5A 1HXGA 3TS7A 3M9UA 3P5PA 1HXCA 5B02A 4KKMA 3KRPA 1VG6A 2PS6A 4P0XA 5DJPF 3RMGA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2E93 A;  5HN9 A;  1N1B A;  2E8V A;  3N1V F;  5JV2 F;  2OPM A;  3WCM A;  3G4F A;  4LTV A;  1HXA A;  3LEE A;  5IMP A;  4LA5 A;  2F94 F;  5AFX A;  4MC3 A;  3LVS A;  3OAB B;  4KUX A;  3CKE A;  3RBM A;  2ZY1 A;  1KIZ A;  3WJN A;  5DJR F;  3WCH A;  1YHL A;  3LDW A;  2ZCO A;  4JZX A;  4E9U A;  4ZQ8 A;  1WL2 A;  4JYX A;  2E8U A;  3WCB A;  4FP4 A;  3QKC A;  3DYG A;  4GP2 A;  1RTR A;  2E8T A;  2H8O A;  5IVG A;  3SAE A;  3VJA A;  4DWB A;  3WCJ A;  5KSX F;  4OMH A;  3WSB A;  4KWD A;  1ZW5 A;  2Z4Y A;  3BNY A;  3G4D A;  3Q2Z A;  4LFV F;  2AZJ A;  5AHU B;  2Z78 A;  5DIQ F;  3VJC A;  3WCE A;  3N3L F;  4NFI F;  1VG4 A;  3Q30 A;  4RXD A;  3ICK A;  2F7M F;  1YYS A;  3TFV A;  2PS8 A;  5DJV F;  2J1P A;  5H9D A;  4LTZ A;  3ACY A;  5DZ2 A;  5B0L A;  4KVI A;  4KFA A;  4LIX A;  2E91 A;  3WJO A;  4NKF A;  5A0I A;  3WE9 A;  3V66 A;  3AQC B;  5JA0 F;  3APZ A;  4QPF A;  3WCL A;  3LG5 A;  2F8Z F;  3KRA B;  3N5H F;  3N49 F;  5EAU A;  2P1C A;  4RXE A;  3NPK A;  3V1V A;  4EA0 A;  2Q80 A;  2EWG A;  5IL8 A;  1N21 A;  4OKZ A;  5IM1 A;  3N0G A;  3DYH A;  4FJQ A;  5ILH A;  4H5C F;  3KRC A;  4LZ3 A;  5DHI A;  3LGK A;  1UBV A;  4KQS A;  1YYR A;  2O1O A;  3WEG A;  3PKO A;  3RYE A;  3KB9 A;  4H5D F;  3EGT A;  5IK0 A;  5B00 A;  2AET A;  4LFG A;  1RQJ A;  5IN8 A;  2OGD A;  4KVY A;  4LUU A;  5B0K A;  1YHK A;  1FPS A;  3AQB B;  3Q1O A;  3VJ8 A;  5ILY A;  4LLT A;  3ICN A;  3ZL6 A;  5IMN A;  3Q2Q A;  2AZL A;  1UBW A;  4F6V A;  3LSN A;  1YHM A;  3PH7 A;  5B0J A;  4P0W A;  1EZF A;  1WY0 A;  4NUA A;  3KRF A;  1VG7 A;  3QQV A;  3WEH A;  2I19 A;  2PS7 A;  4KQU A;  5E8H A;  3ZMC A;  4E9Z A;  4PVX F;  4LXW A;  3CP6 A;  5B0M A;  3V1X A;  4JXN A;  3WCC A;  2DH4 A;  4JXY A;  4DZW A;  5HN7 A;  5AEL A;  2ONH A;  5HNA A;  3N0F A;  3ZCD A;  3SDR A;  4GA3 A;  3N5J F;  3ACW A;  4NFJ F;  3SDU A;  1N20 A;  3UCA A;  1DI1 A;  4XQT F;  2E8W A;  2RAH A;  4EA1 A;  3N6K F;  5IKA A;  3KRO B;  4RYP A;  4UMJ A;  4NKE A;  4MC0 A;  5DHK A;  3OAB A;  2F8C F;  5IK6 A;  1V4E A;  3KBK A;  4XQS F;  5I1U A;  4HD1 A;  4KK2 A;  4RXC A;  1DGP A;  4KVW A;  3B7L A;  3S4J A;  4WK5 A;  1KIY A;  4LPG F;  3ID0 A;  5EAT A;  5JV0 F;  3ACX A;  3W7F A;  3WCA A;  1V4H A;  2Z7H A;  1YYU A;  2ZCS A;  3WCI A;  4F62 A;  4LLS A;  4LPH F;  3TFN A;  2PS4 A;  1WKZ A;  2J5C A;  3N45 F;  3WEK A;  4DHD A;  5DGS F;  1VG3 A;  1N1Z A;  5ILZ A;  2F89 F;  4GAX A;  4OKM A;  2F92 F;  2Q9Z A;  3KRA A;  3P8R A;  3WEJ A;  3AQ0 A;  5B01 A;  3P5R A;  3LZ9 A;  2OPN A;  2E8X A;  1UBY A;  3KRP B;  5IL3 A;  3IPI A;  1YYT A;  3WC9 A;  5HN8 A;  1WL0 A;  2Q58 A;  1PS1 A;  3SDQ A;  3M02 A;  3VJD A;  2Z4V A;  4LOB A;  5C05 A;  5ERN A;  3OYR A;  3WCD A;  3P8L A;  3ICZ A;  3LGZ B;  3S9V A;  5IK9 A;  1JFG A;  2J1O A;  5EAS A;  3BNX A;  4JVJ F;  3ADZ A;  2VF6 A;  1N24 A;  1V4J A;  3RYW A;  3MZV A;  5JV1 F;  2Z52 A;  5ILI A;  4P0V A;  5DW7 A;  4MC8 A;  3IBA A;  3VJ9 A;  2AEL A;  5ERM A;  5DGM F;  1VG2 A;  3OAC A;  5B03 A;  5A0K A;  2E94 A;  1YYQ A;  1V4K A;  3TC1 A;  3ZMB A;  5ER8 A;  5CG6 A;  3EZ3 A;  2QIS A;  3WEF A;  5B0I A;  3M01 A;  3WJK A;  1RQI A;  4LZ0 A;  2OA6 A;  3M0G A;  4DEM F;  5CG5 A;  4RNQ A;  4RXA A;  3WSA A;  3VJB A;  3WCG A;  1YV5 A;  1WL3 A;  5ILJ A;  1YJ4 A;  4E1E A;  3VJE A;  5ILD A;  3SDT A;  2ZEU A;  2Z7I A;  4EA2 A;  1HM4 A;  2E92 A;  3NRI A;  5E8K A;  5IMI A;  4KQ5 A;  2E95 A;  4DWG A;  4OGU A;  3SDV A;  4NFK F;  4F6X A;  4NG6 A;  4DI5 A;  3EFQ A;  5A0J A;  2FTZ A;  3TFP A;  3ICM A;  4LA6 A;  3WCF A;  5JUZ F;  2Z4X A;  4N9U A;  4XQR F;  3N1W F;  1HM7 A;  2AZK A;  3ZOU A;  2F9K F;  1WL1 A;  3DYF A;  4H5E F;  3KRO A;  3WEI A;  4K10 A;  2Z50 A;  3N3D A;  3AE0 A;  3KRC B;  4JZB A;  4Q23 A;  3LOM A;  4KVD A;  4KPD A;  4N1Z F;  4PVY F;  5AYP A;  2E90 A;  1V4I A;  3N46 F;  3P41 A;  4DXJ A;  5E8L A;  2ZEV A;  4LZC A;  3PDE A;  2Z4Z A;  3LLW A;  4QXS F;  2ZCR A;  5ILK A;  1WMW A;  1N23 A;  2ONG A;  3PYB A;  2E4O A;  3CC9 A;  3MAV A;  3M00 A;  2Q9Y A;  1HX9 A;  4KPJ A;  4L2X F;  4LFE A;  2ZCQ A;  1UBX A;  3LJI A;  3NF2 A;  3NPR A;  2FOR A;  1JFA A;  5ERO A;  3KRF B;  3LMD A;  4OMG A;  2AEK A;  1YQ7 A;  2Z4W A;  4GP1 A;  2PS5 A;  1N22 A;  5DGN F;  5IKH A;  3ASX A;  3OAC B;  3PYA A;  3LK5 A;  1HXG A;  3TS7 A;  3M9U A;  3P5P A;  1HXC A;  5B02 A;  4KKM A;  3KRP A;  1VG6 A;  2PS6 A;  4P0X A;  5DJP F;  3RMG A; 
#chains in the Genus database with same CATH topology
 2E93 A;  5HN9 A;  1N1B A;  2E8V A;  3N1V F;  5JV2 F;  2OPM A;  3WCM A;  3G4F A;  4LTV A;  1HXA A;  3LEE A;  5IMP A;  4LA5 A;  2F94 F;  5AFX A;  4MC3 A;  3LVS A;  3OAB B;  4KUX A;  3CKE A;  3RBM A;  2ZY1 A;  1KIZ A;  3WJN A;  5DJR F;  3WCH A;  1YHL A;  3LDW A;  2ZCO A;  4JZX A;  4E9U A;  4ZQ8 A;  1WL2 A;  4JYX A;  2E8U A;  3WCB A;  4FP4 A;  3QKC A;  3DYG A;  4GP2 A;  1RTR A;  2E8T A;  2H8O A;  5IVG A;  3SAE A;  3VJA A;  4DWB A;  3WCJ A;  5KSX F;  4OMH A;  3WSB A;  4KWD A;  1ZW5 A;  2Z4Y A;  3BNY A;  3G4D A;  3Q2Z A;  4LFV F;  2AZJ A;  5AHU B;  2Z78 A;  5DIQ F;  3VJC A;  3WCE A;  3N3L F;  4NFI F;  1VG4 A;  3Q30 A;  4RXD A;  3ICK A;  2F7M F;  1YYS A;  3TFV A;  2PS8 A;  5DJV F;  2J1P A;  5H9D A;  4LTZ A;  3ACY A;  5DZ2 A;  5B0L A;  4KVI A;  4KFA A;  4LIX A;  2E91 A;  3WJO A;  4NKF A;  5A0I A;  3WE9 A;  3V66 A;  3AQC B;  5JA0 F;  3APZ A;  4QPF A;  3WCL A;  3LG5 A;  2F8Z F;  3KRA B;  3N5H F;  3N49 F;  5EAU A;  2P1C A;  4RXE A;  3NPK A;  3V1V A;  4EA0 A;  2Q80 A;  2EWG A;  5IL8 A;  1N21 A;  4OKZ A;  5IM1 A;  3N0G A;  3DYH A;  4FJQ A;  5ILH A;  4H5C F;  3KRC A;  4LZ3 A;  5DHI A;  3LGK A;  1UBV A;  4KQS A;  1YYR A;  2O1O A;  3WEG A;  3PKO A;  3RYE A;  3KB9 A;  4H5D F;  3EGT A;  5IK0 A;  5B00 A;  2AET A;  4LFG A;  1RQJ A;  5IN8 A;  2OGD A;  4KVY A;  4LUU A;  5B0K A;  1YHK A;  1FPS A;  3AQB B;  3Q1O A;  3VJ8 A;  5ILY A;  4LLT A;  3ICN A;  3ZL6 A;  5IMN A;  3Q2Q A;  2AZL A;  1UBW A;  4F6V A;  3LSN A;  1YHM A;  3PH7 A;  5B0J A;  4P0W A;  1EZF A;  1WY0 A;  4NUA A;  3KRF A;  1VG7 A;  3QQV A;  3WEH A;  2I19 A;  2PS7 A;  4KQU A;  5E8H A;  3ZMC A;  4E9Z A;  4PVX F;  4LXW A;  3CP6 A;  5B0M A;  3V1X A;  4JXN A;  3WCC A;  2DH4 A;  4JXY A;  4DZW A;  5HN7 A;  5AEL A;  2ONH A;  5HNA A;  3N0F A;  3ZCD A;  3SDR A;  4GA3 A;  3N5J F;  3ACW A;  4NFJ F;  3SDU A;  1N20 A;  3UCA A;  1DI1 A;  4XQT F;  2E8W A;  2RAH A;  4EA1 A;  3N6K F;  5IKA A;  3KRO B;  4RYP A;  4UMJ A;  4NKE A;  4MC0 A;  5DHK A;  3OAB A;  2F8C F;  5IK6 A;  1V4E A;  3KBK A;  4XQS F;  5I1U A;  4HD1 A;  4KK2 A;  4RXC A;  1DGP A;  4KVW A;  3B7L A;  3S4J A;  4WK5 A;  1KIY A;  4LPG F;  3ID0 A;  5EAT A;  5JV0 F;  3ACX A;  3W7F A;  3WCA A;  1V4H A;  2Z7H A;  1YYU A;  2ZCS A;  3WCI A;  4F62 A;  4LLS A;  4LPH F;  3TFN A;  2PS4 A;  1WKZ A;  2J5C A;  3N45 F;  3WEK A;  4DHD A;  5DGS F;  1VG3 A;  1N1Z A;  5ILZ A;  2F89 F;  4GAX A;  4OKM A;  2F92 F;  2Q9Z A;  3KRA A;  3P8R A;  3WEJ A;  3AQ0 A;  5B01 A;  3P5R A;  3LZ9 A;  2OPN A;  2E8X A;  1UBY A;  3KRP B;  5IL3 A;  3IPI A;  1YYT A;  3WC9 A;  5HN8 A;  1WL0 A;  2Q58 A;  1PS1 A;  3SDQ A;  3M02 A;  3VJD A;  2Z4V A;  4LOB A;  5C05 A;  5ERN A;  3OYR A;  3WCD A;  3P8L A;  3ICZ A;  3LGZ B;  3S9V A;  5IK9 A;  1JFG A;  2J1O A;  5EAS A;  3BNX A;  4JVJ F;  3ADZ A;  2VF6 A;  1N24 A;  1V4J A;  3RYW A;  3MZV A;  5JV1 F;  2Z52 A;  5ILI A;  4P0V A;  5DW7 A;  4MC8 A;  3IBA A;  3VJ9 A;  2AEL A;  5ERM A;  5DGM F;  1VG2 A;  3OAC A;  5B03 A;  5A0K A;  2E94 A;  1YYQ A;  1V4K A;  3TC1 A;  3ZMB A;  5ER8 A;  5CG6 A;  3EZ3 A;  2QIS A;  3WEF A;  5B0I A;  3M01 A;  3WJK A;  1RQI A;  4LZ0 A;  2OA6 A;  3M0G A;  4DEM F;  5CG5 A;  4RNQ A;  4RXA A;  3WSA A;  3VJB A;  3WCG A;  1YV5 A;  1WL3 A;  5ILJ A;  1YJ4 A;  4E1E A;  3VJE A;  5ILD A;  3SDT A;  2ZEU A;  2Z7I A;  4EA2 A;  1HM4 A;  2E92 A;  3NRI A;  5E8K A;  5IMI A;  4KQ5 A;  2E95 A;  4DWG A;  4OGU A;  3SDV A;  4NFK F;  4F6X A;  4NG6 A;  4DI5 A;  3EFQ A;  5A0J A;  2FTZ A;  3TFP A;  3ICM A;  4LA6 A;  3WCF A;  5JUZ F;  2Z4X A;  4N9U A;  4XQR F;  3N1W F;  1HM7 A;  2AZK A;  3ZOU A;  2F9K F;  1WL1 A;  3DYF A;  4H5E F;  3KRO A;  3WEI A;  4K10 A;  2Z50 A;  3N3D A;  3AE0 A;  3KRC B;  4JZB A;  4Q23 A;  3LOM A;  4KVD A;  4KPD A;  4N1Z F;  4PVY F;  5AYP A;  2E90 A;  1V4I A;  3N46 F;  3P41 A;  4DXJ A;  5E8L A;  2ZEV A;  4LZC A;  3PDE A;  2Z4Z A;  3LLW A;  4QXS F;  2ZCR A;  5ILK A;  1WMW A;  1N23 A;  2ONG A;  3PYB A;  2E4O A;  3CC9 A;  3MAV A;  3M00 A;  2Q9Y A;  1HX9 A;  4KPJ A;  4L2X F;  4LFE A;  2ZCQ A;  1UBX A;  3LJI A;  3NF2 A;  3NPR A;  2FOR A;  1JFA A;  5ERO A;  3KRF B;  3LMD A;  4OMG A;  2AEK A;  1YQ7 A;  2Z4W A;  4GP1 A;  2PS5 A;  1N22 A;  5DGN F;  5IKH A;  3ASX A;  3OAC B;  3PYA A;  3LK5 A;  1HXG A;  3TS7 A;  3M9U A;  3P5P A;  1HXC A;  5B02 A;  4KKM A;  3KRP A;  1VG6 A;  2PS6 A;  4P0X A;  5DJP F;  3RMG A; 
#chains in the Genus database with same CATH homology
 2E93 A;  5HN9 A;  1N1B A;  2E8V A;  3N1V F;  5JV2 F;  2OPM A;  3WCM A;  3G4F A;  4LTV A;  1HXA A;  3LEE A;  5IMP A;  4LA5 A;  2F94 F;  5AFX A;  4MC3 A;  3LVS A;  3OAB B;  4KUX A;  3CKE A;  3RBM A;  2ZY1 A;  1KIZ A;  3WJN A;  5DJR F;  3WCH A;  1YHL A;  3LDW A;  2ZCO A;  4JZX A;  4E9U A;  4ZQ8 A;  1WL2 A;  4JYX A;  2E8U A;  3WCB A;  4FP4 A;  3QKC A;  3DYG A;  4GP2 A;  1RTR A;  2E8T A;  2H8O A;  5IVG A;  3SAE A;  3VJA A;  4DWB A;  3WCJ A;  5KSX F;  4OMH A;  3WSB A;  4KWD A;  1ZW5 A;  2Z4Y A;  3BNY A;  3G4D A;  3Q2Z A;  4LFV F;  2AZJ A;  5AHU B;  2Z78 A;  5DIQ F;  3VJC A;  3WCE A;  3N3L F;  4NFI F;  1VG4 A;  3Q30 A;  4RXD A;  3ICK A;  2F7M F;  1YYS A;  3TFV A;  2PS8 A;  5DJV F;  2J1P A;  5H9D A;  4LTZ A;  3ACY A;  5DZ2 A;  5B0L A;  4KVI A;  4KFA A;  4LIX A;  2E91 A;  3WJO A;  4NKF A;  5A0I A;  3WE9 A;  3V66 A;  3AQC B;  5JA0 F;  3APZ A;  4QPF A;  3WCL A;  3LG5 A;  2F8Z F;  3KRA B;  3N5H F;  3N49 F;  5EAU A;  2P1C A;  4RXE A;  3NPK A;  3V1V A;  4EA0 A;  2Q80 A;  2EWG A;  5IL8 A;  1N21 A;  4OKZ A;  5IM1 A;  3N0G A;  3DYH A;  4FJQ A;  5ILH A;  4H5C F;  3KRC A;  4LZ3 A;  5DHI A;  3LGK A;  1UBV A;  4KQS A;  1YYR A;  2O1O A;  3WEG A;  3PKO A;  3RYE A;  3KB9 A;  4H5D F;  3EGT A;  5IK0 A;  5B00 A;  2AET A;  4LFG A;  1RQJ A;  5IN8 A;  2OGD A;  4KVY A;  4LUU A;  5B0K A;  1YHK A;  1FPS A;  3AQB B;  3Q1O A;  3VJ8 A;  5ILY A;  4LLT A;  3ICN A;  3ZL6 A;  5IMN A;  3Q2Q A;  2AZL A;  1UBW A;  4F6V A;  3LSN A;  1YHM A;  3PH7 A;  5B0J A;  4P0W A;  1EZF A;  1WY0 A;  4NUA A;  3KRF A;  1VG7 A;  3QQV A;  3WEH A;  2I19 A;  2PS7 A;  4KQU A;  5E8H A;  3ZMC A;  4E9Z A;  4PVX F;  4LXW A;  3CP6 A;  5B0M A;  3V1X A;  4JXN A;  3WCC A;  2DH4 A;  4JXY A;  4DZW A;  5HN7 A;  5AEL A;  2ONH A;  5HNA A;  3N0F A;  3ZCD A;  3SDR A;  4GA3 A;  3N5J F;  3ACW A;  4NFJ F;  3SDU A;  1N20 A;  3UCA A;  1DI1 A;  4XQT F;  2E8W A;  2RAH A;  4EA1 A;  3N6K F;  5IKA A;  3KRO B;  4RYP A;  4UMJ A;  4NKE A;  4MC0 A;  5DHK A;  3OAB A;  2F8C F;  5IK6 A;  1V4E A;  3KBK A;  4XQS F;  5I1U A;  4HD1 A;  4KK2 A;  4RXC A;  1DGP A;  4KVW A;  3B7L A;  3S4J A;  4WK5 A;  1KIY A;  4LPG F;  3ID0 A;  5EAT A;  5JV0 F;  3ACX A;  3W7F A;  3WCA A;  1V4H A;  2Z7H A;  1YYU A;  2ZCS A;  3WCI A;  4F62 A;  4LLS A;  4LPH F;  3TFN A;  2PS4 A;  1WKZ A;  2J5C A;  3N45 F;  3WEK A;  4DHD A;  5DGS F;  1VG3 A;  1N1Z A;  5ILZ A;  2F89 F;  4GAX A;  4OKM A;  2F92 F;  2Q9Z A;  3KRA A;  3P8R A;  3WEJ A;  3AQ0 A;  5B01 A;  3P5R A;  3LZ9 A;  2OPN A;  2E8X A;  1UBY A;  3KRP B;  5IL3 A;  3IPI A;  1YYT A;  3WC9 A;  5HN8 A;  1WL0 A;  2Q58 A;  1PS1 A;  3SDQ A;  3M02 A;  3VJD A;  2Z4V A;  4LOB A;  5C05 A;  5ERN A;  3OYR A;  3WCD A;  3P8L A;  3ICZ A;  3LGZ B;  3S9V A;  5IK9 A;  1JFG A;  2J1O A;  5EAS A;  3BNX A;  4JVJ F;  3ADZ A;  2VF6 A;  1N24 A;  1V4J A;  3RYW A;  3MZV A;  5JV1 F;  2Z52 A;  5ILI A;  4P0V A;  5DW7 A;  4MC8 A;  3IBA A;  3VJ9 A;  2AEL A;  5ERM A;  5DGM F;  1VG2 A;  3OAC A;  5B03 A;  5A0K A;  2E94 A;  1YYQ A;  1V4K A;  3TC1 A;  3ZMB A;  5ER8 A;  5CG6 A;  3EZ3 A;  2QIS A;  3WEF A;  5B0I A;  3M01 A;  3WJK A;  1RQI A;  4LZ0 A;  2OA6 A;  3M0G A;  4DEM F;  5CG5 A;  4RNQ A;  4RXA A;  3WSA A;  3VJB A;  3WCG A;  1YV5 A;  1WL3 A;  5ILJ A;  1YJ4 A;  4E1E A;  3VJE A;  5ILD A;  3SDT A;  2ZEU A;  2Z7I A;  4EA2 A;  1HM4 A;  2E92 A;  3NRI A;  5E8K A;  5IMI A;  4KQ5 A;  2E95 A;  4DWG A;  4OGU A;  3SDV A;  4NFK F;  4F6X A;  4NG6 A;  4DI5 A;  3EFQ A;  5A0J A;  2FTZ A;  3TFP A;  3ICM A;  4LA6 A;  3WCF A;  5JUZ F;  2Z4X A;  4N9U A;  4XQR F;  3N1W F;  1HM7 A;  2AZK A;  3ZOU A;  2F9K F;  1WL1 A;  3DYF A;  4H5E F;  3KRO A;  3WEI A;  4K10 A;  2Z50 A;  3N3D A;  3AE0 A;  3KRC B;  4JZB A;  4Q23 A;  3LOM A;  4KVD A;  4KPD A;  4N1Z F;  4PVY F;  5AYP A;  2E90 A;  1V4I A;  3N46 F;  3P41 A;  4DXJ A;  5E8L A;  2ZEV A;  4LZC A;  3PDE A;  2Z4Z A;  3LLW A;  4QXS F;  2ZCR A;  5ILK A;  1WMW A;  1N23 A;  2ONG A;  3PYB A;  2E4O A;  3CC9 A;  3MAV A;  3M00 A;  2Q9Y A;  1HX9 A;  4KPJ A;  4L2X F;  4LFE A;  2ZCQ A;  1UBX A;  3LJI A;  3NF2 A;  3NPR A;  2FOR A;  1JFA A;  5ERO A;  3KRF B;  3LMD A;  4OMG A;  2AEK A;  1YQ7 A;  2Z4W A;  4GP1 A;  2PS5 A;  1N22 A;  5DGN F;  5IKH A;  3ASX A;  3OAC B;  3PYA A;  3LK5 A;  1HXG A;  3TS7 A;  3M9U A;  3P5P A;  1HXC A;  5B02 A;  4KKM A;  3KRP A;  1VG6 A;  2PS6 A;  4P0X A;  5DJP F;  3RMG A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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