5JUZF

Crystal structure of human fpps in complex with an allosteric inhibitor cl-06-057
Total Genus 123
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
123
sequence length
341
structure length
336
Chain Sequence
YAQEKQDFVQHFSQIVRVLTEHPEIGDAIARLKEVLEYNAIGGKYNRGLTVVVAFRELVEPRKQDADSLQRAWTVGWCVELLQAFFLVADDIMDSSLTRRGQICWYQKPGVGLDAINDANLLEACIYRLLKLYCREQPYYLNLIELFLQSSYQTEIGQTLDLLTAPQNVDLVRFTEKRYKSIVKYKTAFYSFYLPIAAAMYMAGIDGEKEHANAKKILLEMGEFFQIQDDYLDLFGDPSVTGKIGTDIQDNKCSWLVVQCLQRATPEQYQILKENYGQKEAEKVARVKALYEELDLPAVFLQYEEDSYSHIMALIEQYAAPLPPAVFLGLARKIYK
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Transferase/transferase inhibitor
molecule keywords Farnesyl pyrophosphate synthase
publication title Pharmacophore Mapping of Thienopyrimidine-Based Monophosphonate (ThP-MP) Inhibitors of the Human Farnesyl Pyrophosphate Synthase.
pubmed doi rcsb
source organism Homo sapiens
total genus 123
structure length 336
sequence length 341
ec nomenclature ec 2.5.1.1: Dimethylallyltranstransferase.
pdb deposition date 2016-05-10

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
F PF00348 polyprenyl_synt Polyprenyl synthetase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.600.10 Mainly Alpha Orthogonal Bundle Farnesyl Diphosphate Synthase Farnesyl Diphosphate Synthase 5juzF00
4P0XA 1YHMA 3KRCB 4RXAA 3V1XA 3PYBA 4OGUA 2Z4XA 5DJRF 3G4FA 1VG6A 3ACXA 3M02A 2Z4WA 5AYPA 3ASXA 4DXJA 5B0MA 4KVWA 3AQCB 3SDUA 3N0FA 1YYQA 4LOBA 1YYTA 2P1CA 1UBYA 1KIYA 2E91A 5DIQF 4KUXA 3WSBA 2Q80A 2E8VA 1YYUA 1YYSA 4EA1A 4DI5A 3WCCA 3VJ9A 3LZ9A 3TFPA 3N5JF 3MZVA 3S9VA 3RYWA 5JV1F 3VJCA 3M00A 3WJNA 2PS6A 3Q2QA 2OPNA 5DGNF 1N24A 5ILKA 3VJ8A 5KSXF 3TS7A 5HNAA 1UBWA 3TC1A 5IK6A 3UCAA 5IL3A 3ACWA 5DGSF 1HXCA 4H5DF 3Q1OA 4LTZA 5ILZA 3SDVA 1WL2A 4LPHF 3WCLA 3WCMA 3ZL6A 2E8TA 4JZXA 3WJOA 3PH7A 4LTVA 4ZQ8A 4E9ZA 5IMNA 2ZCQA 2ZCOA 3TFVA 2F94F 5B03A 2ONGA 2J1OA 3M9UA 5B01A 4MC8A 3KRFB 3NRIA 2OGDA 4LZ3A 1WMWA 3LGKA 4L2XF 3LK5A 3LOMA 2FORA 5DZ2A 1HM4A 4LZCA 5ER8A 3M0GA 4N1ZF 3KRPA 4GA3A 3TFNA 5B02A 4H5EF 5DW7A 3LSNA 4LFGA 3IPIA 3LLWA 3P5PA 4KFAA 3WCEA 3WEKA 4LIXA 4LXWA 1HXGA 1N1ZA 1HXAA 1HM7A 4GAXA 2E8WA 4OKZA 2FTZA 3WCGA 5JV2F 3LGZB 4JYXA 1ZW5A 1WL3A 1FPSA 3KROB 3N49F 2Z52A 2AZJA 1WY0A 2H8OA 2Z78A 2PS5A 4NFKF 3G4DA 3WCAA 3N1VF 4K10A 5B0JA 3LDWA 4RYPA 2J1PA 4MC0A 5C05A 3WCHA 3AE0A 2ZEVA 2F8CF 4GP1A 2OPMA 3WCBA 4F6XA 4GP2A 2PS4A 1YQ7A 1V4HA 4LUUA 1YV5A 3MAVA 3KRAA 4RNQA 5IKHA 3NPRA 3N3LF 1VG3A 3KRFA 3WEGA 3P8RA 4EA0A 4KPDA 2Z4VA 2E8XA 4MC3A 4DWGA 3OACA 1JFAA 3W7FA 3P8LA 1V4KA 4HD1A 3OYRA 5AHUB 2E94A 3N6KF 4JXYA 4PVYF 2AETA 3QQVA 3LVSA 4KQSA 3OABA 5HN8A 4RXCA 5DGMF 1YHKA 1WL1A 4NG6A 3AQ0A 5IM1A 5IKAA 5ERNA 2AZLA 2E90A 5E8KA 3KROA 4KVDA 3WEHA 3VJBA 4KQUA 1DI1A 3KRCA 5ERMA 5A0IA 3RMGA 3ICMA 3WEFA 4QPFA 5DHKA 3VJEA 5JV0F 4N9UA 2F8ZF 3N3DA 1UBXA 4OMHA 5EROA 1V4JA 3P5RA 5IK0A 2E95A 2Q9YA 4XQTF 2F92F 4JZBA 3ICNA 4RXDA 3ZOUA 1N1BA 3NPKA 5IK9A 2DH4A 1HX9A 3CP6A 3Q2ZA 3WCFA 2Z4YA 1JFGA 3ADZA 5EAUA 3WCDA 3APZA 4DWBA 2QISA 2Z7HA 3PYAA 3DYHA 5E8HA 2AZKA 5AFXA 3WC9A 5B00A 4F62A 4DZWA 1WL0A 2I19A 4P0WA 5ILDA 5A0JA 3CKEA 4EA2A 3ZCDA 5B0LA 3WSAA 3V66A 4OKMA 1N20A 3VJAA 1V4EA 2E8UA 1RQJA 3WCJA 3Q30A 4LFEA 1DGPA 3BNXA 2Z4ZA 2J5CA 4UMJA 4LLTA 4F6VA 3V1VA 2E4OA 4KVIA 1VG4A 4P0VA 5HN7A 4KVYA 3ZMCA 2PS7A 5ILIA 5E8LA 5A0KA 3LEEA 3N5HF 2ZCRA 3LG5A 3EGTA 4NUAA 5JUZF 3N0GA 4LA6A 2Q58A 3B7LA 4KQ5A 4JXNA 4NKEA 2E93A 5IVGA 4PVXF 4KKMA 3EFQA 3N46F 4LLSA 2OA6A 4LFVF 4DEMF 1VG7A 4KPJA 5AELA 3WCIA 4XQRF 3KRPB 5CG5A 3N45F 3NF2A 4DHDA 5HN9A 5I1UA 4QXSF 5ILYA 3RYEA 2O1OA 2EWGA 2PS8A 4NFJF 1N23A 5IL8A 4WK5A 2ONHA 1WKZA 3S4JA 3CC9A 3LJIA 3SDRA 2AELA 4LZ0A 5B0IA 4FP4A 5CG6A 4E1EA 1PS1A 4JVJF 4LA5A 4NKFA 4NFIF 2ZEUA 3P41A 3QKCA 2F89F 2F9KF 3N1WF 3ICKA 5IMIA 2Z7IA 4KWDA 1YHLA 3BNYA 3VJDA 2AEKA 4KK2A 1YYRA 2E92A 4XQSF 2F7MF 4H5CF 4E9UA 5DJPF 3ACYA 2ZCSA 4Q23A 5ILJA 3WJKA 3WEJA 3KBKA 5ILHA 5IMPA 5JA0F 3IBAA 3PKOA 3KRAB 3LMDA 4RXEA 2VF6A 3AQBB 3RBMA 5IN8A 2ZY1A 1RQIA 1EZFA 3WE9A 3SAEA 5DJVF 3OACB 4LPGF 3ZMBA 4FJQA 3WEIA 3ICZA 1KIZA 4OMGA 5H9DA 1RTRA 5DHIA 2RAHA 3KB9A 1N21A 3M01A 1N22A 3SDQA 3OABB 5EASA 3EZ3A 5EATA 2Z50A 1VG2A 3DYFA 3SDTA 3ID0A 1UBVA 3PDEA 1YJ4A 3DYGA 5B0KA 2Q9ZA 1V4IA
chains in the Genus database with same CATH superfamily
4P0XA 1YHMA 3KRCB 4RXAA 3V1XA 3PYBA 4OGUA 2Z4XA 5DJRF 3G4FA 1VG6A 3ACXA 3M02A 2Z4WA 5AYPA 3ASXA 4DXJA 5B0MA 4KVWA 3AQCB 3SDUA 3N0FA 1YYQA 4LOBA 1YYTA 2P1CA 1UBYA 1KIYA 2E91A 5DIQF 4KUXA 3WSBA 2Q80A 2E8VA 1YYUA 1YYSA 4EA1A 4DI5A 3WCCA 3VJ9A 3LZ9A 3TFPA 3N5JF 3MZVA 3S9VA 3RYWA 5JV1F 3VJCA 3M00A 3WJNA 2PS6A 3Q2QA 2OPNA 5DGNF 1N24A 5ILKA 3VJ8A 5KSXF 3TS7A 5HNAA 1UBWA 3TC1A 5IK6A 3UCAA 5IL3A 3ACWA 5DGSF 1HXCA 4H5DF 3Q1OA 4LTZA 5ILZA 3SDVA 1WL2A 4LPHF 3WCLA 3WCMA 3ZL6A 2E8TA 4JZXA 3WJOA 3PH7A 4LTVA 4ZQ8A 4E9ZA 5IMNA 2ZCQA 2ZCOA 3TFVA 2F94F 5B03A 2ONGA 2J1OA 3M9UA 5B01A 4MC8A 3KRFB 3NRIA 2OGDA 4LZ3A 1WMWA 3LGKA 4L2XF 3LK5A 3LOMA 2FORA 5DZ2A 1HM4A 4LZCA 5ER8A 3M0GA 4N1ZF 3KRPA 4GA3A 3TFNA 5B02A 4H5EF 5DW7A 3LSNA 4LFGA 3IPIA 3LLWA 3P5PA 4KFAA 3WCEA 3WEKA 4LIXA 4LXWA 1HXGA 1N1ZA 1HXAA 1HM7A 4GAXA 2E8WA 4OKZA 2FTZA 3WCGA 5JV2F 3LGZB 4JYXA 1ZW5A 1WL3A 1FPSA 3KROB 3N49F 2Z52A 2AZJA 1WY0A 2H8OA 2Z78A 2PS5A 4NFKF 3G4DA 3WCAA 3N1VF 4K10A 5B0JA 3LDWA 4RYPA 2J1PA 4MC0A 5C05A 3WCHA 3AE0A 2ZEVA 2F8CF 4GP1A 2OPMA 3WCBA 4F6XA 4GP2A 2PS4A 1YQ7A 1V4HA 4LUUA 1YV5A 3MAVA 3KRAA 4RNQA 5IKHA 3NPRA 3N3LF 1VG3A 3KRFA 3WEGA 3P8RA 4EA0A 4KPDA 2Z4VA 2E8XA 4MC3A 4DWGA 3OACA 1JFAA 3W7FA 3P8LA 1V4KA 4HD1A 3OYRA 5AHUB 2E94A 3N6KF 4JXYA 4PVYF 2AETA 3QQVA 3LVSA 4KQSA 3OABA 5HN8A 4RXCA 5DGMF 1YHKA 1WL1A 4NG6A 3AQ0A 5IM1A 5IKAA 5ERNA 2AZLA 2E90A 5E8KA 3KROA 4KVDA 3WEHA 3VJBA 4KQUA 1DI1A 3KRCA 5ERMA 5A0IA 3RMGA 3ICMA 3WEFA 4QPFA 5DHKA 3VJEA 5JV0F 4N9UA 2F8ZF 3N3DA 1UBXA 4OMHA 5EROA 1V4JA 3P5RA 5IK0A 2E95A 2Q9YA 4XQTF 2F92F 4JZBA 3ICNA 4RXDA 3ZOUA 1N1BA 3NPKA 5IK9A 2DH4A 1HX9A 3CP6A 3Q2ZA 3WCFA 2Z4YA 1JFGA 3ADZA 5EAUA 3WCDA 3APZA 4DWBA 2QISA 2Z7HA 3PYAA 3DYHA 5E8HA 2AZKA 5AFXA 3WC9A 5B00A 4F62A 4DZWA 1WL0A 2I19A 4P0WA 5ILDA 5A0JA 3CKEA 4EA2A 3ZCDA 5B0LA 3WSAA 3V66A 4OKMA 1N20A 3VJAA 1V4EA 2E8UA 1RQJA 3WCJA 3Q30A 4LFEA 1DGPA 3BNXA 2Z4ZA 2J5CA 4UMJA 4LLTA 4F6VA 3V1VA 2E4OA 4KVIA 1VG4A 4P0VA 5HN7A 4KVYA 3ZMCA 2PS7A 5ILIA 5E8LA 5A0KA 3LEEA 3N5HF 2ZCRA 3LG5A 3EGTA 4NUAA 5JUZF 3N0GA 4LA6A 2Q58A 3B7LA 4KQ5A 4JXNA 4NKEA 2E93A 5IVGA 4PVXF 4KKMA 3EFQA 3N46F 4LLSA 2OA6A 4LFVF 4DEMF 1VG7A 4KPJA 5AELA 3WCIA 4XQRF 3KRPB 5CG5A 3N45F 3NF2A 4DHDA 5HN9A 5I1UA 4QXSF 5ILYA 3RYEA 2O1OA 2EWGA 2PS8A 4NFJF 1N23A 5IL8A 4WK5A 2ONHA 1WKZA 3S4JA 3CC9A 3LJIA 3SDRA 2AELA 4LZ0A 5B0IA 4FP4A 5CG6A 4E1EA 1PS1A 4JVJF 4LA5A 4NKFA 4NFIF 2ZEUA 3P41A 3QKCA 2F89F 2F9KF 3N1WF 3ICKA 5IMIA 2Z7IA 4KWDA 1YHLA 3BNYA 3VJDA 2AEKA 4KK2A 1YYRA 2E92A 4XQSF 2F7MF 4H5CF 4E9UA 5DJPF 3ACYA 2ZCSA 4Q23A 5ILJA 3WJKA 3WEJA 3KBKA 5ILHA 5IMPA 5JA0F 3IBAA 3PKOA 3KRAB 3LMDA 4RXEA 2VF6A 3AQBB 3RBMA 5IN8A 2ZY1A 1RQIA 1EZFA 3WE9A 3SAEA 5DJVF 3OACB 4LPGF 3ZMBA 4FJQA 3WEIA 3ICZA 1KIZA 4OMGA 5H9DA 1RTRA 5DHIA 2RAHA 3KB9A 1N21A 3M01A 1N22A 3SDQA 3OABB 5EASA 3EZ3A 5EATA 2Z50A 1VG2A 3DYFA 3SDTA 3ID0A 1UBVA 3PDEA 1YJ4A 3DYGA 5B0KA 2Q9ZA 1V4IA
chains in the Genus database with same CATH topology
4P0XA 1YHMA 3KRCB 4RXAA 3V1XA 3PYBA 4OGUA 2Z4XA 5DJRF 3G4FA 1VG6A 3ACXA 3M02A 2Z4WA 5AYPA 3ASXA 4DXJA 5B0MA 4KVWA 3AQCB 3SDUA 3N0FA 1YYQA 4LOBA 1YYTA 2P1CA 1UBYA 1KIYA 2E91A 5DIQF 4KUXA 3WSBA 2Q80A 2E8VA 1YYUA 1YYSA 4EA1A 4DI5A 3WCCA 3VJ9A 3LZ9A 3TFPA 3N5JF 3MZVA 3S9VA 3RYWA 5JV1F 3VJCA 3M00A 3WJNA 2PS6A 3Q2QA 2OPNA 5DGNF 1N24A 5ILKA 3VJ8A 5KSXF 3TS7A 5HNAA 1UBWA 3TC1A 5IK6A 3UCAA 5IL3A 3ACWA 5DGSF 1HXCA 4H5DF 3Q1OA 4LTZA 5ILZA 3SDVA 1WL2A 4LPHF 3WCLA 3WCMA 3ZL6A 2E8TA 4JZXA 3WJOA 3PH7A 4LTVA 4ZQ8A 4E9ZA 5IMNA 2ZCQA 2ZCOA 3TFVA 2F94F 5B03A 2ONGA 2J1OA 3M9UA 5B01A 4MC8A 3KRFB 3NRIA 2OGDA 4LZ3A 1WMWA 3LGKA 4L2XF 3LK5A 3LOMA 2FORA 5DZ2A 1HM4A 4LZCA 5ER8A 3M0GA 4N1ZF 3KRPA 4GA3A 3TFNA 5B02A 4H5EF 5DW7A 3LSNA 4LFGA 3IPIA 3LLWA 3P5PA 4KFAA 3WCEA 3WEKA 4LIXA 4LXWA 1HXGA 1N1ZA 1HXAA 1HM7A 4GAXA 2E8WA 4OKZA 2FTZA 3WCGA 5JV2F 3LGZB 4JYXA 1ZW5A 1WL3A 1FPSA 3KROB 3N49F 2Z52A 2AZJA 1WY0A 2H8OA 2Z78A 2PS5A 4NFKF 3G4DA 3WCAA 3N1VF 4K10A 5B0JA 3LDWA 4RYPA 2J1PA 4MC0A 5C05A 3WCHA 3AE0A 2ZEVA 2F8CF 4GP1A 2OPMA 3WCBA 4F6XA 4GP2A 2PS4A 1YQ7A 1V4HA 4LUUA 1YV5A 3MAVA 3KRAA 4RNQA 5IKHA 3NPRA 3N3LF 1VG3A 3KRFA 3WEGA 3P8RA 4EA0A 4KPDA 2Z4VA 2E8XA 4MC3A 4DWGA 3OACA 1JFAA 3W7FA 3P8LA 1V4KA 4HD1A 3OYRA 5AHUB 2E94A 3N6KF 4JXYA 4PVYF 2AETA 3QQVA 3LVSA 4KQSA 3OABA 5HN8A 4RXCA 5DGMF 1YHKA 1WL1A 4NG6A 3AQ0A 5IM1A 5IKAA 5ERNA 2AZLA 2E90A 5E8KA 3KROA 4KVDA 3WEHA 3VJBA 4KQUA 1DI1A 3KRCA 5ERMA 5A0IA 3RMGA 3ICMA 3WEFA 4QPFA 5DHKA 3VJEA 5JV0F 4N9UA 2F8ZF 3N3DA 1UBXA 4OMHA 5EROA 1V4JA 3P5RA 5IK0A 2E95A 2Q9YA 4XQTF 2F92F 4JZBA 3ICNA 4RXDA 3ZOUA 1N1BA 3NPKA 5IK9A 2DH4A 1HX9A 3CP6A 3Q2ZA 3WCFA 2Z4YA 1JFGA 3ADZA 5EAUA 3WCDA 3APZA 4DWBA 2QISA 2Z7HA 3PYAA 3DYHA 5E8HA 2AZKA 5AFXA 3WC9A 5B00A 4F62A 4DZWA 1WL0A 2I19A 4P0WA 5ILDA 5A0JA 3CKEA 4EA2A 3ZCDA 5B0LA 3WSAA 3V66A 4OKMA 1N20A 3VJAA 1V4EA 2E8UA 1RQJA 3WCJA 3Q30A 4LFEA 1DGPA 3BNXA 2Z4ZA 2J5CA 4UMJA 4LLTA 4F6VA 3V1VA 2E4OA 4KVIA 1VG4A 4P0VA 5HN7A 4KVYA 3ZMCA 2PS7A 5ILIA 5E8LA 5A0KA 3LEEA 3N5HF 2ZCRA 3LG5A 3EGTA 4NUAA 5JUZF 3N0GA 4LA6A 2Q58A 3B7LA 4KQ5A 4JXNA 4NKEA 2E93A 5IVGA 4PVXF 4KKMA 3EFQA 3N46F 4LLSA 2OA6A 4LFVF 4DEMF 1VG7A 4KPJA 5AELA 3WCIA 4XQRF 3KRPB 5CG5A 3N45F 3NF2A 4DHDA 5HN9A 5I1UA 4QXSF 5ILYA 3RYEA 2O1OA 2EWGA 2PS8A 4NFJF 1N23A 5IL8A 4WK5A 2ONHA 1WKZA 3S4JA 3CC9A 3LJIA 3SDRA 2AELA 4LZ0A 5B0IA 4FP4A 5CG6A 4E1EA 1PS1A 4JVJF 4LA5A 4NKFA 4NFIF 2ZEUA 3P41A 3QKCA 2F89F 2F9KF 3N1WF 3ICKA 5IMIA 2Z7IA 4KWDA 1YHLA 3BNYA 3VJDA 2AEKA 4KK2A 1YYRA 2E92A 4XQSF 2F7MF 4H5CF 4E9UA 5DJPF 3ACYA 2ZCSA 4Q23A 5ILJA 3WJKA 3WEJA 3KBKA 5ILHA 5IMPA 5JA0F 3IBAA 3PKOA 3KRAB 3LMDA 4RXEA 2VF6A 3AQBB 3RBMA 5IN8A 2ZY1A 1RQIA 1EZFA 3WE9A 3SAEA 5DJVF 3OACB 4LPGF 3ZMBA 4FJQA 3WEIA 3ICZA 1KIZA 4OMGA 5H9DA 1RTRA 5DHIA 2RAHA 3KB9A 1N21A 3M01A 1N22A 3SDQA 3OABB 5EASA 3EZ3A 5EATA 2Z50A 1VG2A 3DYFA 3SDTA 3ID0A 1UBVA 3PDEA 1YJ4A 3DYGA 5B0KA 2Q9ZA 1V4IA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4P0X A;  1YHM A;  3KRC B;  4RXA A;  3V1X A;  3PYB A;  4OGU A;  2Z4X A;  5DJR F;  3G4F A;  1VG6 A;  3ACX A;  3M02 A;  2Z4W A;  5AYP A;  3ASX A;  4DXJ A;  5B0M A;  4KVW A;  3AQC B;  3SDU A;  3N0F A;  1YYQ A;  4LOB A;  1YYT A;  2P1C A;  1UBY A;  1KIY A;  2E91 A;  5DIQ F;  4KUX A;  3WSB A;  2Q80 A;  2E8V A;  1YYU A;  1YYS A;  4EA1 A;  4DI5 A;  3WCC A;  3VJ9 A;  3LZ9 A;  3TFP A;  3N5J F;  3MZV A;  3S9V A;  3RYW A;  5JV1 F;  3VJC A;  3M00 A;  3WJN A;  2PS6 A;  3Q2Q A;  2OPN A;  5DGN F;  1N24 A;  5ILK A;  3VJ8 A;  5KSX F;  3TS7 A;  5HNA A;  1UBW A;  3TC1 A;  5IK6 A;  3UCA A;  5IL3 A;  3ACW A;  5DGS F;  1HXC A;  4H5D F;  3Q1O A;  4LTZ A;  5ILZ A;  3SDV A;  1WL2 A;  4LPH F;  3WCL A;  3WCM A;  3ZL6 A;  2E8T A;  4JZX A;  3WJO A;  3PH7 A;  4LTV A;  4ZQ8 A;  4E9Z A;  5IMN A;  2ZCQ A;  2ZCO A;  3TFV A;  2F94 F;  5B03 A;  2ONG A;  2J1O A;  3M9U A;  5B01 A;  4MC8 A;  3KRF B;  3NRI A;  2OGD A;  4LZ3 A;  1WMW A;  3LGK A;  4L2X F;  3LK5 A;  3LOM A;  2FOR A;  5DZ2 A;  1HM4 A;  4LZC A;  5ER8 A;  3M0G A;  4N1Z F;  3KRP A;  4GA3 A;  3TFN A;  5B02 A;  4H5E F;  5DW7 A;  3LSN A;  4LFG A;  3IPI A;  3LLW A;  3P5P A;  4KFA A;  3WCE A;  3WEK A;  4LIX A;  4LXW A;  1HXG A;  1N1Z A;  1HXA A;  1HM7 A;  4GAX A;  2E8W A;  4OKZ A;  2FTZ A;  3WCG A;  5JV2 F;  3LGZ B;  4JYX A;  1ZW5 A;  1WL3 A;  1FPS A;  3KRO B;  3N49 F;  2Z52 A;  2AZJ A;  1WY0 A;  2H8O A;  2Z78 A;  2PS5 A;  4NFK F;  3G4D A;  3WCA A;  3N1V F;  4K10 A;  5B0J A;  3LDW A;  4RYP A;  2J1P A;  4MC0 A;  5C05 A;  3WCH A;  3AE0 A;  2ZEV A;  2F8C F;  4GP1 A;  2OPM A;  3WCB A;  4F6X A;  4GP2 A;  2PS4 A;  1YQ7 A;  1V4H A;  4LUU A;  1YV5 A;  3MAV A;  3KRA A;  4RNQ A;  5IKH A;  3NPR A;  3N3L F;  1VG3 A;  3KRF A;  3WEG A;  3P8R A;  4EA0 A;  4KPD A;  2Z4V A;  2E8X A;  4MC3 A;  4DWG A;  3OAC A;  1JFA A;  3W7F A;  3P8L A;  1V4K A;  4HD1 A;  3OYR A;  5AHU B;  2E94 A;  3N6K F;  4JXY A;  4PVY F;  2AET A;  3QQV A;  3LVS A;  4KQS A;  3OAB A;  5HN8 A;  4RXC A;  5DGM F;  1YHK A;  1WL1 A;  4NG6 A;  3AQ0 A;  5IM1 A;  5IKA A;  5ERN A;  2AZL A;  2E90 A;  5E8K A;  3KRO A;  4KVD A;  3WEH A;  3VJB A;  4KQU A;  1DI1 A;  3KRC A;  5ERM A;  5A0I A;  3RMG A;  3ICM A;  3WEF A;  4QPF A;  5DHK A;  3VJE A;  5JV0 F;  4N9U A;  2F8Z F;  3N3D A;  1UBX A;  4OMH A;  5ERO A;  1V4J A;  3P5R A;  5IK0 A;  2E95 A;  2Q9Y A;  4XQT F;  2F92 F;  4JZB A;  3ICN A;  4RXD A;  3ZOU A;  1N1B A;  3NPK A;  5IK9 A;  2DH4 A;  1HX9 A;  3CP6 A;  3Q2Z A;  3WCF A;  2Z4Y A;  1JFG A;  3ADZ A;  5EAU A;  3WCD A;  3APZ A;  4DWB A;  2QIS A;  2Z7H A;  3PYA A;  3DYH A;  5E8H A;  2AZK A;  5AFX A;  3WC9 A;  5B00 A;  4F62 A;  4DZW A;  1WL0 A;  2I19 A;  4P0W A;  5ILD A;  5A0J A;  3CKE A;  4EA2 A;  3ZCD A;  5B0L A;  3WSA A;  3V66 A;  4OKM A;  1N20 A;  3VJA A;  1V4E A;  2E8U A;  1RQJ A;  3WCJ A;  3Q30 A;  4LFE A;  1DGP A;  3BNX A;  2Z4Z A;  2J5C A;  4UMJ A;  4LLT A;  4F6V A;  3V1V A;  2E4O A;  4KVI A;  1VG4 A;  4P0V A;  5HN7 A;  4KVY A;  3ZMC A;  2PS7 A;  5ILI A;  5E8L A;  5A0K A;  3LEE A;  3N5H F;  2ZCR A;  3LG5 A;  3EGT A;  4NUA A;  5JUZ F;  3N0G A;  4LA6 A;  2Q58 A;  3B7L A;  4KQ5 A;  4JXN A;  4NKE A;  2E93 A;  5IVG A;  4PVX F;  4KKM A;  3EFQ A;  3N46 F;  4LLS A;  2OA6 A;  4LFV F;  4DEM F;  1VG7 A;  4KPJ A;  5AEL A;  3WCI A;  4XQR F;  3KRP B;  5CG5 A;  3N45 F;  3NF2 A;  4DHD A;  5HN9 A;  5I1U A;  4QXS F;  5ILY A;  3RYE A;  2O1O A;  2EWG A;  2PS8 A;  4NFJ F;  1N23 A;  5IL8 A;  4WK5 A;  2ONH A;  1WKZ A;  3S4J A;  3CC9 A;  3LJI A;  3SDR A;  2AEL A;  4LZ0 A;  5B0I A;  4FP4 A;  5CG6 A;  4E1E A;  1PS1 A;  4JVJ F;  4LA5 A;  4NKF A;  4NFI F;  2ZEU A;  3P41 A;  3QKC A;  2F89 F;  2F9K F;  3N1W F;  3ICK A;  5IMI A;  2Z7I A;  4KWD A;  1YHL A;  3BNY A;  3VJD A;  2AEK A;  4KK2 A;  1YYR A;  2E92 A;  4XQS F;  2F7M F;  4H5C F;  4E9U A;  5DJP F;  3ACY A;  2ZCS A;  4Q23 A;  5ILJ A;  3WJK A;  3WEJ A;  3KBK A;  5ILH A;  5IMP A;  5JA0 F;  3IBA A;  3PKO A;  3KRA B;  3LMD A;  4RXE A;  2VF6 A;  3AQB B;  3RBM A;  5IN8 A;  2ZY1 A;  1RQI A;  1EZF A;  3WE9 A;  3SAE A;  5DJV F;  3OAC B;  4LPG F;  3ZMB A;  4FJQ A;  3WEI A;  3ICZ A;  1KIZ A;  4OMG A;  5H9D A;  1RTR A;  5DHI A;  2RAH A;  3KB9 A;  1N21 A;  3M01 A;  1N22 A;  3SDQ A;  3OAB B;  5EAS A;  3EZ3 A;  5EAT A;  2Z50 A;  1VG2 A;  3DYF A;  3SDT A;  3ID0 A;  1UBV A;  3PDE A;  1YJ4 A;  3DYG A;  5B0K A;  2Q9Z A;  1V4I A; 
#chains in the Genus database with same CATH topology
 4P0X A;  1YHM A;  3KRC B;  4RXA A;  3V1X A;  3PYB A;  4OGU A;  2Z4X A;  5DJR F;  3G4F A;  1VG6 A;  3ACX A;  3M02 A;  2Z4W A;  5AYP A;  3ASX A;  4DXJ A;  5B0M A;  4KVW A;  3AQC B;  3SDU A;  3N0F A;  1YYQ A;  4LOB A;  1YYT A;  2P1C A;  1UBY A;  1KIY A;  2E91 A;  5DIQ F;  4KUX A;  3WSB A;  2Q80 A;  2E8V A;  1YYU A;  1YYS A;  4EA1 A;  4DI5 A;  3WCC A;  3VJ9 A;  3LZ9 A;  3TFP A;  3N5J F;  3MZV A;  3S9V A;  3RYW A;  5JV1 F;  3VJC A;  3M00 A;  3WJN A;  2PS6 A;  3Q2Q A;  2OPN A;  5DGN F;  1N24 A;  5ILK A;  3VJ8 A;  5KSX F;  3TS7 A;  5HNA A;  1UBW A;  3TC1 A;  5IK6 A;  3UCA A;  5IL3 A;  3ACW A;  5DGS F;  1HXC A;  4H5D F;  3Q1O A;  4LTZ A;  5ILZ A;  3SDV A;  1WL2 A;  4LPH F;  3WCL A;  3WCM A;  3ZL6 A;  2E8T A;  4JZX A;  3WJO A;  3PH7 A;  4LTV A;  4ZQ8 A;  4E9Z A;  5IMN A;  2ZCQ A;  2ZCO A;  3TFV A;  2F94 F;  5B03 A;  2ONG A;  2J1O A;  3M9U A;  5B01 A;  4MC8 A;  3KRF B;  3NRI A;  2OGD A;  4LZ3 A;  1WMW A;  3LGK A;  4L2X F;  3LK5 A;  3LOM A;  2FOR A;  5DZ2 A;  1HM4 A;  4LZC A;  5ER8 A;  3M0G A;  4N1Z F;  3KRP A;  4GA3 A;  3TFN A;  5B02 A;  4H5E F;  5DW7 A;  3LSN A;  4LFG A;  3IPI A;  3LLW A;  3P5P A;  4KFA A;  3WCE A;  3WEK A;  4LIX A;  4LXW A;  1HXG A;  1N1Z A;  1HXA A;  1HM7 A;  4GAX A;  2E8W A;  4OKZ A;  2FTZ A;  3WCG A;  5JV2 F;  3LGZ B;  4JYX A;  1ZW5 A;  1WL3 A;  1FPS A;  3KRO B;  3N49 F;  2Z52 A;  2AZJ A;  1WY0 A;  2H8O A;  2Z78 A;  2PS5 A;  4NFK F;  3G4D A;  3WCA A;  3N1V F;  4K10 A;  5B0J A;  3LDW A;  4RYP A;  2J1P A;  4MC0 A;  5C05 A;  3WCH A;  3AE0 A;  2ZEV A;  2F8C F;  4GP1 A;  2OPM A;  3WCB A;  4F6X A;  4GP2 A;  2PS4 A;  1YQ7 A;  1V4H A;  4LUU A;  1YV5 A;  3MAV A;  3KRA A;  4RNQ A;  5IKH A;  3NPR A;  3N3L F;  1VG3 A;  3KRF A;  3WEG A;  3P8R A;  4EA0 A;  4KPD A;  2Z4V A;  2E8X A;  4MC3 A;  4DWG A;  3OAC A;  1JFA A;  3W7F A;  3P8L A;  1V4K A;  4HD1 A;  3OYR A;  5AHU B;  2E94 A;  3N6K F;  4JXY A;  4PVY F;  2AET A;  3QQV A;  3LVS A;  4KQS A;  3OAB A;  5HN8 A;  4RXC A;  5DGM F;  1YHK A;  1WL1 A;  4NG6 A;  3AQ0 A;  5IM1 A;  5IKA A;  5ERN A;  2AZL A;  2E90 A;  5E8K A;  3KRO A;  4KVD A;  3WEH A;  3VJB A;  4KQU A;  1DI1 A;  3KRC A;  5ERM A;  5A0I A;  3RMG A;  3ICM A;  3WEF A;  4QPF A;  5DHK A;  3VJE A;  5JV0 F;  4N9U A;  2F8Z F;  3N3D A;  1UBX A;  4OMH A;  5ERO A;  1V4J A;  3P5R A;  5IK0 A;  2E95 A;  2Q9Y A;  4XQT F;  2F92 F;  4JZB A;  3ICN A;  4RXD A;  3ZOU A;  1N1B A;  3NPK A;  5IK9 A;  2DH4 A;  1HX9 A;  3CP6 A;  3Q2Z A;  3WCF A;  2Z4Y A;  1JFG A;  3ADZ A;  5EAU A;  3WCD A;  3APZ A;  4DWB A;  2QIS A;  2Z7H A;  3PYA A;  3DYH A;  5E8H A;  2AZK A;  5AFX A;  3WC9 A;  5B00 A;  4F62 A;  4DZW A;  1WL0 A;  2I19 A;  4P0W A;  5ILD A;  5A0J A;  3CKE A;  4EA2 A;  3ZCD A;  5B0L A;  3WSA A;  3V66 A;  4OKM A;  1N20 A;  3VJA A;  1V4E A;  2E8U A;  1RQJ A;  3WCJ A;  3Q30 A;  4LFE A;  1DGP A;  3BNX A;  2Z4Z A;  2J5C A;  4UMJ A;  4LLT A;  4F6V A;  3V1V A;  2E4O A;  4KVI A;  1VG4 A;  4P0V A;  5HN7 A;  4KVY A;  3ZMC A;  2PS7 A;  5ILI A;  5E8L A;  5A0K A;  3LEE A;  3N5H F;  2ZCR A;  3LG5 A;  3EGT A;  4NUA A;  5JUZ F;  3N0G A;  4LA6 A;  2Q58 A;  3B7L A;  4KQ5 A;  4JXN A;  4NKE A;  2E93 A;  5IVG A;  4PVX F;  4KKM A;  3EFQ A;  3N46 F;  4LLS A;  2OA6 A;  4LFV F;  4DEM F;  1VG7 A;  4KPJ A;  5AEL A;  3WCI A;  4XQR F;  3KRP B;  5CG5 A;  3N45 F;  3NF2 A;  4DHD A;  5HN9 A;  5I1U A;  4QXS F;  5ILY A;  3RYE A;  2O1O A;  2EWG A;  2PS8 A;  4NFJ F;  1N23 A;  5IL8 A;  4WK5 A;  2ONH A;  1WKZ A;  3S4J A;  3CC9 A;  3LJI A;  3SDR A;  2AEL A;  4LZ0 A;  5B0I A;  4FP4 A;  5CG6 A;  4E1E A;  1PS1 A;  4JVJ F;  4LA5 A;  4NKF A;  4NFI F;  2ZEU A;  3P41 A;  3QKC A;  2F89 F;  2F9K F;  3N1W F;  3ICK A;  5IMI A;  2Z7I A;  4KWD A;  1YHL A;  3BNY A;  3VJD A;  2AEK A;  4KK2 A;  1YYR A;  2E92 A;  4XQS F;  2F7M F;  4H5C F;  4E9U A;  5DJP F;  3ACY A;  2ZCS A;  4Q23 A;  5ILJ A;  3WJK A;  3WEJ A;  3KBK A;  5ILH A;  5IMP A;  5JA0 F;  3IBA A;  3PKO A;  3KRA B;  3LMD A;  4RXE A;  2VF6 A;  3AQB B;  3RBM A;  5IN8 A;  2ZY1 A;  1RQI A;  1EZF A;  3WE9 A;  3SAE A;  5DJV F;  3OAC B;  4LPG F;  3ZMB A;  4FJQ A;  3WEI A;  3ICZ A;  1KIZ A;  4OMG A;  5H9D A;  1RTR A;  5DHI A;  2RAH A;  3KB9 A;  1N21 A;  3M01 A;  1N22 A;  3SDQ A;  3OAB B;  5EAS A;  3EZ3 A;  5EAT A;  2Z50 A;  1VG2 A;  3DYF A;  3SDT A;  3ID0 A;  1UBV A;  3PDE A;  1YJ4 A;  3DYG A;  5B0K A;  2Q9Z A;  1V4I A; 
#chains in the Genus database with same CATH homology
 4P0X A;  1YHM A;  3KRC B;  4RXA A;  3V1X A;  3PYB A;  4OGU A;  2Z4X A;  5DJR F;  3G4F A;  1VG6 A;  3ACX A;  3M02 A;  2Z4W A;  5AYP A;  3ASX A;  4DXJ A;  5B0M A;  4KVW A;  3AQC B;  3SDU A;  3N0F A;  1YYQ A;  4LOB A;  1YYT A;  2P1C A;  1UBY A;  1KIY A;  2E91 A;  5DIQ F;  4KUX A;  3WSB A;  2Q80 A;  2E8V A;  1YYU A;  1YYS A;  4EA1 A;  4DI5 A;  3WCC A;  3VJ9 A;  3LZ9 A;  3TFP A;  3N5J F;  3MZV A;  3S9V A;  3RYW A;  5JV1 F;  3VJC A;  3M00 A;  3WJN A;  2PS6 A;  3Q2Q A;  2OPN A;  5DGN F;  1N24 A;  5ILK A;  3VJ8 A;  5KSX F;  3TS7 A;  5HNA A;  1UBW A;  3TC1 A;  5IK6 A;  3UCA A;  5IL3 A;  3ACW A;  5DGS F;  1HXC A;  4H5D F;  3Q1O A;  4LTZ A;  5ILZ A;  3SDV A;  1WL2 A;  4LPH F;  3WCL A;  3WCM A;  3ZL6 A;  2E8T A;  4JZX A;  3WJO A;  3PH7 A;  4LTV A;  4ZQ8 A;  4E9Z A;  5IMN A;  2ZCQ A;  2ZCO A;  3TFV A;  2F94 F;  5B03 A;  2ONG A;  2J1O A;  3M9U A;  5B01 A;  4MC8 A;  3KRF B;  3NRI A;  2OGD A;  4LZ3 A;  1WMW A;  3LGK A;  4L2X F;  3LK5 A;  3LOM A;  2FOR A;  5DZ2 A;  1HM4 A;  4LZC A;  5ER8 A;  3M0G A;  4N1Z F;  3KRP A;  4GA3 A;  3TFN A;  5B02 A;  4H5E F;  5DW7 A;  3LSN A;  4LFG A;  3IPI A;  3LLW A;  3P5P A;  4KFA A;  3WCE A;  3WEK A;  4LIX A;  4LXW A;  1HXG A;  1N1Z A;  1HXA A;  1HM7 A;  4GAX A;  2E8W A;  4OKZ A;  2FTZ A;  3WCG A;  5JV2 F;  3LGZ B;  4JYX A;  1ZW5 A;  1WL3 A;  1FPS A;  3KRO B;  3N49 F;  2Z52 A;  2AZJ A;  1WY0 A;  2H8O A;  2Z78 A;  2PS5 A;  4NFK F;  3G4D A;  3WCA A;  3N1V F;  4K10 A;  5B0J A;  3LDW A;  4RYP A;  2J1P A;  4MC0 A;  5C05 A;  3WCH A;  3AE0 A;  2ZEV A;  2F8C F;  4GP1 A;  2OPM A;  3WCB A;  4F6X A;  4GP2 A;  2PS4 A;  1YQ7 A;  1V4H A;  4LUU A;  1YV5 A;  3MAV A;  3KRA A;  4RNQ A;  5IKH A;  3NPR A;  3N3L F;  1VG3 A;  3KRF A;  3WEG A;  3P8R A;  4EA0 A;  4KPD A;  2Z4V A;  2E8X A;  4MC3 A;  4DWG A;  3OAC A;  1JFA A;  3W7F A;  3P8L A;  1V4K A;  4HD1 A;  3OYR A;  5AHU B;  2E94 A;  3N6K F;  4JXY A;  4PVY F;  2AET A;  3QQV A;  3LVS A;  4KQS A;  3OAB A;  5HN8 A;  4RXC A;  5DGM F;  1YHK A;  1WL1 A;  4NG6 A;  3AQ0 A;  5IM1 A;  5IKA A;  5ERN A;  2AZL A;  2E90 A;  5E8K A;  3KRO A;  4KVD A;  3WEH A;  3VJB A;  4KQU A;  1DI1 A;  3KRC A;  5ERM A;  5A0I A;  3RMG A;  3ICM A;  3WEF A;  4QPF A;  5DHK A;  3VJE A;  5JV0 F;  4N9U A;  2F8Z F;  3N3D A;  1UBX A;  4OMH A;  5ERO A;  1V4J A;  3P5R A;  5IK0 A;  2E95 A;  2Q9Y A;  4XQT F;  2F92 F;  4JZB A;  3ICN A;  4RXD A;  3ZOU A;  1N1B A;  3NPK A;  5IK9 A;  2DH4 A;  1HX9 A;  3CP6 A;  3Q2Z A;  3WCF A;  2Z4Y A;  1JFG A;  3ADZ A;  5EAU A;  3WCD A;  3APZ A;  4DWB A;  2QIS A;  2Z7H A;  3PYA A;  3DYH A;  5E8H A;  2AZK A;  5AFX A;  3WC9 A;  5B00 A;  4F62 A;  4DZW A;  1WL0 A;  2I19 A;  4P0W A;  5ILD A;  5A0J A;  3CKE A;  4EA2 A;  3ZCD A;  5B0L A;  3WSA A;  3V66 A;  4OKM A;  1N20 A;  3VJA A;  1V4E A;  2E8U A;  1RQJ A;  3WCJ A;  3Q30 A;  4LFE A;  1DGP A;  3BNX A;  2Z4Z A;  2J5C A;  4UMJ A;  4LLT A;  4F6V A;  3V1V A;  2E4O A;  4KVI A;  1VG4 A;  4P0V A;  5HN7 A;  4KVY A;  3ZMC A;  2PS7 A;  5ILI A;  5E8L A;  5A0K A;  3LEE A;  3N5H F;  2ZCR A;  3LG5 A;  3EGT A;  4NUA A;  5JUZ F;  3N0G A;  4LA6 A;  2Q58 A;  3B7L A;  4KQ5 A;  4JXN A;  4NKE A;  2E93 A;  5IVG A;  4PVX F;  4KKM A;  3EFQ A;  3N46 F;  4LLS A;  2OA6 A;  4LFV F;  4DEM F;  1VG7 A;  4KPJ A;  5AEL A;  3WCI A;  4XQR F;  3KRP B;  5CG5 A;  3N45 F;  3NF2 A;  4DHD A;  5HN9 A;  5I1U A;  4QXS F;  5ILY A;  3RYE A;  2O1O A;  2EWG A;  2PS8 A;  4NFJ F;  1N23 A;  5IL8 A;  4WK5 A;  2ONH A;  1WKZ A;  3S4J A;  3CC9 A;  3LJI A;  3SDR A;  2AEL A;  4LZ0 A;  5B0I A;  4FP4 A;  5CG6 A;  4E1E A;  1PS1 A;  4JVJ F;  4LA5 A;  4NKF A;  4NFI F;  2ZEU A;  3P41 A;  3QKC A;  2F89 F;  2F9K F;  3N1W F;  3ICK A;  5IMI A;  2Z7I A;  4KWD A;  1YHL A;  3BNY A;  3VJD A;  2AEK A;  4KK2 A;  1YYR A;  2E92 A;  4XQS F;  2F7M F;  4H5C F;  4E9U A;  5DJP F;  3ACY A;  2ZCS A;  4Q23 A;  5ILJ A;  3WJK A;  3WEJ A;  3KBK A;  5ILH A;  5IMP A;  5JA0 F;  3IBA A;  3PKO A;  3KRA B;  3LMD A;  4RXE A;  2VF6 A;  3AQB B;  3RBM A;  5IN8 A;  2ZY1 A;  1RQI A;  1EZF A;  3WE9 A;  3SAE A;  5DJV F;  3OAC B;  4LPG F;  3ZMB A;  4FJQ A;  3WEI A;  3ICZ A;  1KIZ A;  4OMG A;  5H9D A;  1RTR A;  5DHI A;  2RAH A;  3KB9 A;  1N21 A;  3M01 A;  1N22 A;  3SDQ A;  3OAB B;  5EAS A;  3EZ3 A;  5EAT A;  2Z50 A;  1VG2 A;  3DYF A;  3SDT A;  3ID0 A;  1UBV A;  3PDE A;  1YJ4 A;  3DYG A;  5B0K A;  2Q9Z A;  1V4I A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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