5JV0F

Crystal structure of human fpps in complex with an allosteric inhibitor cl-08-038
Total Genus 131

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
131
sequence length
343
structure length
341
Chain Sequence
DVYAQEKQDFVQHFSQIVRVLTEDEMGHPEIGDAIARLKEVLEYNAIGGKYNRGLTVVVAFRELVEPRKQDADSLQRAWTVGWCVELLQAFFLVADDIMDSSLTRRGQICWYQKPGVGLDAINDANLLEACIYRLLKLYCREQPYYLNLIELFLQSSYQTEIGQTLDLLTAPNVDLVRFTEKRYKSIVKYKTAFYSFYLPIAAAMYMAGIDGEKEHANAKKILLEMGEFFQIQDDYLDLFGDPSVTGKIGTDIQDNKCSWLVVQCLQRATPEQYQILKENYGQKEAEKVARVKALYEELDLPAVFLQYEEDSYSHIMALIEQYAAPLPPAVFLGLARKIYK
5010015020025030030025020015010050
020406080100120Genus Matrix

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
3H1 (74-76)AH1 (10-29)TI1 (32-35)O1 (29-31)TIV1 (33-36)TI2 (35-38)AH2 (38-53)TII1 (121-124)AH4 (79-107)AH14 (338-347)AH7 (190-216)AH5 (126-148)TIV2 (111-114)TIV4 (122-125)AH6 (152-177)3H3 (185-187)AH8 (222-249)AH9 (252-255)AH11 (280-289)EMPTYTII2 (289-292)AH13 (310-333)TIV5 (334-337)AH10 (269-277)AH12 (295-308)AH3 (59-71)3H2 (118-120)TVIa1 (333-336)3H4 (262-264)Updating...
connected with : NaN
molecule tags Transferase/transferase inhibitor
source organism Homo sapiens
publication title Pharmacophore Mapping of Thienopyrimidine-Based Monophosphonate (ThP-MP) Inhibitors of the Human Farnesyl Pyrophosphate Synthase.
pubmed doi rcsb
molecule keywords Farnesyl pyrophosphate synthase
total genus 131
structure length 341
sequence length 343
ec nomenclature ec 2.5.1.1: Dimethylallyltranstransferase.
pdb deposition date 2016-05-10

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
F PF00348 polyprenyl_synt Polyprenyl synthetase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.600.10 Mainly Alpha Orthogonal Bundle Farnesyl Diphosphate Synthase Farnesyl Diphosphate Synthase 5jv0F00
1DGPA 3ICKA 3DYHA 5B03A 1N20A 3N0FA 3S9VA 4DWBA 4LFGA 1JFAA 2AZKA 3Q2QA 5IM1A 5C05A 4E1EA 1FPSA 5DW7A 3LSNA 4LZCA 5IN8A 5JUZF 4MC8A 3NF2A 3WCLA 3KRAB 4FJQA 3LGKA 5DGSF 3WEKA 3LJIA 4LLTA 3MAVA 3KROB 4LIXA 2ONHA 1YYRA 3NPKA 2E8VA 3ICMA 3VJ9A 3WEHA 1YYUA 3OYRA 4GP2A 3WCIA 4KUXA 3WEJA 2PS6A 2ZCRA 1VG6A 4MC0A 3LZ9A 5DHKA 4OKZA 3CP6A 1V4IA 2OA6A 2Z4WA 5AYPA 1HXCA 2ZCSA 4PVXF 3N1VF 2F89F 2E91A 2FORA 4GP1A 3QQVA 4P0WA 3SDVA 5B0LA 4N1ZF 4KVDA 4L2XF 1PS1A 4LXWA 3WCAA 2J1PA 1VG2A 5ERNA 1V4JA 1VG3A 4KQSA 2OPMA 3N1WF 3WCJA 2OPNA 5EROA 4RXAA 5E8KA 3M0GA 3BNXA 3RBMA 3WEFA 3M02A 4KQUA 5IKHA 4KQ5A 1YQ7A 2E4OA 2F7MF 4LFEA 1N23A 3PYAA 3WSAA 3SDTA 2PS5A 4RYPA 1UBYA 1JFGA 3BNYA 5DJPF 4NG6A 1N22A 5B0MA 4H5EF 5IVGA 3WCBA 3KBKA 2J1OA 3LLWA 4OMHA 4JZBA 3DYGA 2EWGA 5A0KA 5EATA 3PDEA 2FTZA 2Q80A 2PS8A 4KPJA 4LZ3A 2VF6A 4LA6A 5AFXA 3SAEA 2OGDA 4E9UA 4LPGF 3DYFA 3IBAA 3OABA 3W7FA 1HXAA 2Q9YA 3WJOA 4LLSA 3ASXA 4GAXA 5IL8A 4JVJF 3KB9A 4DZWA 5JA0F 3APZA 1RTRA 4KVYA 1N1BA 3LVSA 3PH7A 3LG5A 4EA0A 1RQIA 2AZJA 5IMNA 1VG4A 2PS7A 3ADZA 3V1VA 3WJNA 3UCAA 2E8TA 3Q30A 3LMDA 2Q58A 3TFPA 5KSXF 5DZ2A 2O1OA 2AETA 1KIZA 3LGZB 3WCCA 3Q2ZA 5CG6A 1YHKA 3KRFB 4NUAA 5HN7A 1HM4A 3ID0A 3VJDA 3CKEA 3EFQA 3ACYA 4KFAA 1HXGA 4NFKF 4LTZA 4QPFA 4FP4A 4JYXA 2ZEVA 3RMGA 3LOMA 4KVIA 4KVWA 3G4DA 3ZMBA 1KIYA 5I1UA 3ZCDA 3KRAA 3SDUA 1ZW5A 2F94F 3B7LA 4LZ0A 3KROA 4XQSF 2Z4XA 4JXNA 2I19A 5H9DA 5CG5A 3PYBA 1WL1A 4XQTF 2E95A 3P8RA 5AHUB 4DWGA 1EZFA 5EASA 5B01A 4EA2A 3TC1A 2RAHA 1WY0A 4H5CF 2E92A 3V1XA 4NFJF 3WCGA 2H8OA 4P0VA 2F9KF 3Q1OA 1UBWA 2ZCOA 3QKCA 3ICNA 3WCHA 3P5RA 4NFIF 1YHMA 4RXEA 5DGNF 4F6VA 3WC9A 2AZLA 5IMIA 3G4FA 4P0XA 2Z4VA 3VJCA 3VJBA 3WCDA 4DXJA 5JV0F 5HN8A 4RXCA 3WCEA 4Q23A 1WL3A 3N45F 2Q9ZA 3IPIA 5A0IA 3AQBB 5DHIA 3NPRA 3WSBA 5IK9A 2E90A 5E8LA 3TS7A 4KKMA 2E94A 3WE9A 1V4HA 2ZY1A 3MZVA 3RYEA 4H5DF 3ACXA 2Z52A 4LFVF 4LTVA 5IK6A 4LPHF 5JV2F 5HNAA 3WCMA 3V66A 3KRPB 3LEEA 4MC3A 5ILZA 1WMWA 5JV1F 4ZQ8A 2ZEUA 2PS4A 4DHDA 5IL3A 3S4JA 1YJ4A 3N46F 2DH4A 3PKOA 2P1CA 3WCFA 4OKMA 1N21A 3P8LA 5ILDA 3N3DA 4RXDA 3AQ0A 2E93A 3ZOUA 2Z4ZA 3N6KF 5B0JA 2F8ZF 5DJVF 2E8UA 3ICZA 1HX9A 4GA3A 3SDRA 4LOBA 4LUUA 2F8CF 4E9ZA 3RYWA 3WEIA 4HD1A 4NKFA 4F6XA 4KPDA 4KK2A 3KRPA 4LA5A 3OACB 1RQJA 1DI1A 5DGMF 1WKZA 4OGUA 4K10A 2ONGA 5IKAA 1VG7A 5ILKA 3WEGA 2Z7HA 2Z7IA 5DJRF 3TFNA 3N5HF 5ILYA 4RNQA 1YYSA 3VJEA 1V4EA 4JXYA 5EAUA 4KWDA 2Z4YA 3AE0A 3TFVA 4WK5A 1UBXA 5IK0A 5HN9A 3M00A 5ERMA 2J5CA 4DI5A 4PVYF 5ILIA 4EA1A 5DIQF 2Z78A 3EZ3A 3ZMCA 3KRFA 1N1ZA 1WL2A 1YV5A 5IMPA 1YHLA 1V4KA 4F62A 4JZXA 4DEMF 5AELA 5B0IA 2Z50A 3OACA 2AELA 3WJKA 1YYTA 4XQRF 2F92F 4NKEA 3KRCB 2E8XA 3EGTA 3N3LF 3OABB 4N9UA 4UMJA 3P41A 2E8WA 5ILHA 5A0JA 1WL0A 3NRIA 3N5JF 1UBVA 3M9UA 3N0GA 3ACWA 3AQCB 5ER8A 5B00A 1YYQA 3LDWA 5ILJA 1N24A 2ZCQA 4OMGA 3P5PA 3ZL6A 3M01A 5E8HA 3N49F 3SDQA 3LK5A 1HM7A 5B02A 3CC9A 2QISA 3VJ8A 4QXSF 5B0KA 2AEKA 3KRCA 3VJAA
chains in the Genus database with same CATH superfamily
1DGPA 3ICKA 3DYHA 5B03A 1N20A 3N0FA 3S9VA 4DWBA 4LFGA 1JFAA 2AZKA 3Q2QA 5IM1A 5C05A 4E1EA 1FPSA 5DW7A 3LSNA 4LZCA 5IN8A 5JUZF 4MC8A 3NF2A 3WCLA 3KRAB 4FJQA 3LGKA 5DGSF 3WEKA 3LJIA 4LLTA 3MAVA 3KROB 4LIXA 2ONHA 1YYRA 3NPKA 2E8VA 3ICMA 3VJ9A 3WEHA 1YYUA 3OYRA 4GP2A 3WCIA 4KUXA 3WEJA 2PS6A 2ZCRA 1VG6A 4MC0A 3LZ9A 5DHKA 4OKZA 3CP6A 1V4IA 2OA6A 2Z4WA 5AYPA 1HXCA 2ZCSA 4PVXF 3N1VF 2F89F 2E91A 2FORA 4GP1A 3QQVA 4P0WA 3SDVA 5B0LA 4N1ZF 4KVDA 4L2XF 1PS1A 4LXWA 3WCAA 2J1PA 1VG2A 5ERNA 1V4JA 1VG3A 4KQSA 2OPMA 3N1WF 3WCJA 2OPNA 5EROA 4RXAA 5E8KA 3M0GA 3BNXA 3RBMA 3WEFA 3M02A 4KQUA 5IKHA 4KQ5A 1YQ7A 2E4OA 2F7MF 4LFEA 1N23A 3PYAA 3WSAA 3SDTA 2PS5A 4RYPA 1UBYA 1JFGA 3BNYA 5DJPF 4NG6A 1N22A 5B0MA 4H5EF 5IVGA 3WCBA 3KBKA 2J1OA 3LLWA 4OMHA 4JZBA 3DYGA 2EWGA 5A0KA 5EATA 3PDEA 2FTZA 2Q80A 2PS8A 4KPJA 4LZ3A 2VF6A 4LA6A 5AFXA 3SAEA 2OGDA 4E9UA 4LPGF 3DYFA 3IBAA 3OABA 3W7FA 1HXAA 2Q9YA 3WJOA 4LLSA 3ASXA 4GAXA 5IL8A 4JVJF 3KB9A 4DZWA 5JA0F 3APZA 1RTRA 4KVYA 1N1BA 3LVSA 3PH7A 3LG5A 4EA0A 1RQIA 2AZJA 5IMNA 1VG4A 2PS7A 3ADZA 3V1VA 3WJNA 3UCAA 2E8TA 3Q30A 3LMDA 2Q58A 3TFPA 5KSXF 5DZ2A 2O1OA 2AETA 1KIZA 3LGZB 3WCCA 3Q2ZA 5CG6A 1YHKA 3KRFB 4NUAA 5HN7A 1HM4A 3ID0A 3VJDA 3CKEA 3EFQA 3ACYA 4KFAA 1HXGA 4NFKF 4LTZA 4QPFA 4FP4A 4JYXA 2ZEVA 3RMGA 3LOMA 4KVIA 4KVWA 3G4DA 3ZMBA 1KIYA 5I1UA 3ZCDA 3KRAA 3SDUA 1ZW5A 2F94F 3B7LA 4LZ0A 3KROA 4XQSF 2Z4XA 4JXNA 2I19A 5H9DA 5CG5A 3PYBA 1WL1A 4XQTF 2E95A 3P8RA 5AHUB 4DWGA 1EZFA 5EASA 5B01A 4EA2A 3TC1A 2RAHA 1WY0A 4H5CF 2E92A 3V1XA 4NFJF 3WCGA 2H8OA 4P0VA 2F9KF 3Q1OA 1UBWA 2ZCOA 3QKCA 3ICNA 3WCHA 3P5RA 4NFIF 1YHMA 4RXEA 5DGNF 4F6VA 3WC9A 2AZLA 5IMIA 3G4FA 4P0XA 2Z4VA 3VJCA 3VJBA 3WCDA 4DXJA 5JV0F 5HN8A 4RXCA 3WCEA 4Q23A 1WL3A 3N45F 2Q9ZA 3IPIA 5A0IA 3AQBB 5DHIA 3NPRA 3WSBA 5IK9A 2E90A 5E8LA 3TS7A 4KKMA 2E94A 3WE9A 1V4HA 2ZY1A 3MZVA 3RYEA 4H5DF 3ACXA 2Z52A 4LFVF 4LTVA 5IK6A 4LPHF 5JV2F 5HNAA 3WCMA 3V66A 3KRPB 3LEEA 4MC3A 5ILZA 1WMWA 5JV1F 4ZQ8A 2ZEUA 2PS4A 4DHDA 5IL3A 3S4JA 1YJ4A 3N46F 2DH4A 3PKOA 2P1CA 3WCFA 4OKMA 1N21A 3P8LA 5ILDA 3N3DA 4RXDA 3AQ0A 2E93A 3ZOUA 2Z4ZA 3N6KF 5B0JA 2F8ZF 5DJVF 2E8UA 3ICZA 1HX9A 4GA3A 3SDRA 4LOBA 4LUUA 2F8CF 4E9ZA 3RYWA 3WEIA 4HD1A 4NKFA 4F6XA 4KPDA 4KK2A 3KRPA 4LA5A 3OACB 1RQJA 1DI1A 5DGMF 1WKZA 4OGUA 4K10A 2ONGA 5IKAA 1VG7A 5ILKA 3WEGA 2Z7HA 2Z7IA 5DJRF 3TFNA 3N5HF 5ILYA 4RNQA 1YYSA 3VJEA 1V4EA 4JXYA 5EAUA 4KWDA 2Z4YA 3AE0A 3TFVA 4WK5A 1UBXA 5IK0A 5HN9A 3M00A 5ERMA 2J5CA 4DI5A 4PVYF 5ILIA 4EA1A 5DIQF 2Z78A 3EZ3A 3ZMCA 3KRFA 1N1ZA 1WL2A 1YV5A 5IMPA 1YHLA 1V4KA 4F62A 4JZXA 4DEMF 5AELA 5B0IA 2Z50A 3OACA 2AELA 3WJKA 1YYTA 4XQRF 2F92F 4NKEA 3KRCB 2E8XA 3EGTA 3N3LF 3OABB 4N9UA 4UMJA 3P41A 2E8WA 5ILHA 5A0JA 1WL0A 3NRIA 3N5JF 1UBVA 3M9UA 3N0GA 3ACWA 3AQCB 5ER8A 5B00A 1YYQA 3LDWA 5ILJA 1N24A 2ZCQA 4OMGA 3P5PA 3ZL6A 3M01A 5E8HA 3N49F 3SDQA 3LK5A 1HM7A 5B02A 3CC9A 2QISA 3VJ8A 4QXSF 5B0KA 2AEKA 3KRCA 3VJAA
chains in the Genus database with same CATH topology
1DGPA 3ICKA 3DYHA 5B03A 1N20A 3N0FA 3S9VA 4DWBA 4LFGA 1JFAA 2AZKA 3Q2QA 5IM1A 5C05A 4E1EA 1FPSA 5DW7A 3LSNA 4LZCA 5IN8A 5JUZF 4MC8A 3NF2A 3WCLA 3KRAB 4FJQA 3LGKA 5DGSF 3WEKA 3LJIA 4LLTA 3MAVA 3KROB 4LIXA 2ONHA 1YYRA 3NPKA 2E8VA 3ICMA 3VJ9A 3WEHA 1YYUA 3OYRA 4GP2A 3WCIA 4KUXA 3WEJA 2PS6A 2ZCRA 1VG6A 4MC0A 3LZ9A 5DHKA 4OKZA 3CP6A 1V4IA 2OA6A 2Z4WA 5AYPA 1HXCA 2ZCSA 4PVXF 3N1VF 2F89F 2E91A 2FORA 4GP1A 3QQVA 4P0WA 3SDVA 5B0LA 4N1ZF 4KVDA 4L2XF 1PS1A 4LXWA 3WCAA 2J1PA 1VG2A 5ERNA 1V4JA 1VG3A 4KQSA 2OPMA 3N1WF 3WCJA 2OPNA 5EROA 4RXAA 5E8KA 3M0GA 3BNXA 3RBMA 3WEFA 3M02A 4KQUA 5IKHA 4KQ5A 1YQ7A 2E4OA 2F7MF 4LFEA 1N23A 3PYAA 3WSAA 3SDTA 2PS5A 4RYPA 1UBYA 1JFGA 3BNYA 5DJPF 4NG6A 1N22A 5B0MA 4H5EF 5IVGA 3WCBA 3KBKA 2J1OA 3LLWA 4OMHA 4JZBA 3DYGA 2EWGA 5A0KA 5EATA 3PDEA 2FTZA 2Q80A 2PS8A 4KPJA 4LZ3A 2VF6A 4LA6A 5AFXA 3SAEA 2OGDA 4E9UA 4LPGF 3DYFA 3IBAA 3OABA 3W7FA 1HXAA 2Q9YA 3WJOA 4LLSA 3ASXA 4GAXA 5IL8A 4JVJF 3KB9A 4DZWA 5JA0F 3APZA 1RTRA 4KVYA 1N1BA 3LVSA 3PH7A 3LG5A 4EA0A 1RQIA 2AZJA 5IMNA 1VG4A 2PS7A 3ADZA 3V1VA 3WJNA 3UCAA 2E8TA 3Q30A 3LMDA 2Q58A 3TFPA 5KSXF 5DZ2A 2O1OA 2AETA 1KIZA 3LGZB 3WCCA 3Q2ZA 5CG6A 1YHKA 3KRFB 4NUAA 5HN7A 1HM4A 3ID0A 3VJDA 3CKEA 3EFQA 3ACYA 4KFAA 1HXGA 4NFKF 4LTZA 4QPFA 4FP4A 4JYXA 2ZEVA 3RMGA 3LOMA 4KVIA 4KVWA 3G4DA 3ZMBA 1KIYA 5I1UA 3ZCDA 3KRAA 3SDUA 1ZW5A 2F94F 3B7LA 4LZ0A 3KROA 4XQSF 2Z4XA 4JXNA 2I19A 5H9DA 5CG5A 3PYBA 1WL1A 4XQTF 2E95A 3P8RA 5AHUB 4DWGA 1EZFA 5EASA 5B01A 4EA2A 3TC1A 2RAHA 1WY0A 4H5CF 2E92A 3V1XA 4NFJF 3WCGA 2H8OA 4P0VA 2F9KF 3Q1OA 1UBWA 2ZCOA 3QKCA 3ICNA 3WCHA 3P5RA 4NFIF 1YHMA 4RXEA 5DGNF 4F6VA 3WC9A 2AZLA 5IMIA 3G4FA 4P0XA 2Z4VA 3VJCA 3VJBA 3WCDA 4DXJA 5JV0F 5HN8A 4RXCA 3WCEA 4Q23A 1WL3A 3N45F 2Q9ZA 3IPIA 5A0IA 3AQBB 5DHIA 3NPRA 3WSBA 5IK9A 2E90A 5E8LA 3TS7A 4KKMA 2E94A 3WE9A 1V4HA 2ZY1A 3MZVA 3RYEA 4H5DF 3ACXA 2Z52A 4LFVF 4LTVA 5IK6A 4LPHF 5JV2F 5HNAA 3WCMA 3V66A 3KRPB 3LEEA 4MC3A 5ILZA 1WMWA 5JV1F 4ZQ8A 2ZEUA 2PS4A 4DHDA 5IL3A 3S4JA 1YJ4A 3N46F 2DH4A 3PKOA 2P1CA 3WCFA 4OKMA 1N21A 3P8LA 5ILDA 3N3DA 4RXDA 3AQ0A 2E93A 3ZOUA 2Z4ZA 3N6KF 5B0JA 2F8ZF 5DJVF 2E8UA 3ICZA 1HX9A 4GA3A 3SDRA 4LOBA 4LUUA 2F8CF 4E9ZA 3RYWA 3WEIA 4HD1A 4NKFA 4F6XA 4KPDA 4KK2A 3KRPA 4LA5A 3OACB 1RQJA 1DI1A 5DGMF 1WKZA 4OGUA 4K10A 2ONGA 5IKAA 1VG7A 5ILKA 3WEGA 2Z7HA 2Z7IA 5DJRF 3TFNA 3N5HF 5ILYA 4RNQA 1YYSA 3VJEA 1V4EA 4JXYA 5EAUA 4KWDA 2Z4YA 3AE0A 3TFVA 4WK5A 1UBXA 5IK0A 5HN9A 3M00A 5ERMA 2J5CA 4DI5A 4PVYF 5ILIA 4EA1A 5DIQF 2Z78A 3EZ3A 3ZMCA 3KRFA 1N1ZA 1WL2A 1YV5A 5IMPA 1YHLA 1V4KA 4F62A 4JZXA 4DEMF 5AELA 5B0IA 2Z50A 3OACA 2AELA 3WJKA 1YYTA 4XQRF 2F92F 4NKEA 3KRCB 2E8XA 3EGTA 3N3LF 3OABB 4N9UA 4UMJA 3P41A 2E8WA 5ILHA 5A0JA 1WL0A 3NRIA 3N5JF 1UBVA 3M9UA 3N0GA 3ACWA 3AQCB 5ER8A 5B00A 1YYQA 3LDWA 5ILJA 1N24A 2ZCQA 4OMGA 3P5PA 3ZL6A 3M01A 5E8HA 3N49F 3SDQA 3LK5A 1HM7A 5B02A 3CC9A 2QISA 3VJ8A 4QXSF 5B0KA 2AEKA 3KRCA 3VJAA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1DGP A;  3ICK A;  3DYH A;  5B03 A;  1N20 A;  3N0F A;  3S9V A;  4DWB A;  4LFG A;  1JFA A;  2AZK A;  3Q2Q A;  5IM1 A;  5C05 A;  4E1E A;  1FPS A;  5DW7 A;  3LSN A;  4LZC A;  5IN8 A;  5JUZ F;  4MC8 A;  3NF2 A;  3WCL A;  3KRA B;  4FJQ A;  3LGK A;  5DGS F;  3WEK A;  3LJI A;  4LLT A;  3MAV A;  3KRO B;  4LIX A;  2ONH A;  1YYR A;  3NPK A;  2E8V A;  3ICM A;  3VJ9 A;  3WEH A;  1YYU A;  3OYR A;  4GP2 A;  3WCI A;  4KUX A;  3WEJ A;  2PS6 A;  2ZCR A;  1VG6 A;  4MC0 A;  3LZ9 A;  5DHK A;  4OKZ A;  3CP6 A;  1V4I A;  2OA6 A;  2Z4W A;  5AYP A;  1HXC A;  2ZCS A;  4PVX F;  3N1V F;  2F89 F;  2E91 A;  2FOR A;  4GP1 A;  3QQV A;  4P0W A;  3SDV A;  5B0L A;  4N1Z F;  4KVD A;  4L2X F;  1PS1 A;  4LXW A;  3WCA A;  2J1P A;  1VG2 A;  5ERN A;  1V4J A;  1VG3 A;  4KQS A;  2OPM A;  3N1W F;  3WCJ A;  2OPN A;  5ERO A;  4RXA A;  5E8K A;  3M0G A;  3BNX A;  3RBM A;  3WEF A;  3M02 A;  4KQU A;  5IKH A;  4KQ5 A;  1YQ7 A;  2E4O A;  2F7M F;  4LFE A;  1N23 A;  3PYA A;  3WSA A;  3SDT A;  2PS5 A;  4RYP A;  1UBY A;  1JFG A;  3BNY A;  5DJP F;  4NG6 A;  1N22 A;  5B0M A;  4H5E F;  5IVG A;  3WCB A;  3KBK A;  2J1O A;  3LLW A;  4OMH A;  4JZB A;  3DYG A;  2EWG A;  5A0K A;  5EAT A;  3PDE A;  2FTZ A;  2Q80 A;  2PS8 A;  4KPJ A;  4LZ3 A;  2VF6 A;  4LA6 A;  5AFX A;  3SAE A;  2OGD A;  4E9U A;  4LPG F;  3DYF A;  3IBA A;  3OAB A;  3W7F A;  1HXA A;  2Q9Y A;  3WJO A;  4LLS A;  3ASX A;  4GAX A;  5IL8 A;  4JVJ F;  3KB9 A;  4DZW A;  5JA0 F;  3APZ A;  1RTR A;  4KVY A;  1N1B A;  3LVS A;  3PH7 A;  3LG5 A;  4EA0 A;  1RQI A;  2AZJ A;  5IMN A;  1VG4 A;  2PS7 A;  3ADZ A;  3V1V A;  3WJN A;  3UCA A;  2E8T A;  3Q30 A;  3LMD A;  2Q58 A;  3TFP A;  5KSX F;  5DZ2 A;  2O1O A;  2AET A;  1KIZ A;  3LGZ B;  3WCC A;  3Q2Z A;  5CG6 A;  1YHK A;  3KRF B;  4NUA A;  5HN7 A;  1HM4 A;  3ID0 A;  3VJD A;  3CKE A;  3EFQ A;  3ACY A;  4KFA A;  1HXG A;  4NFK F;  4LTZ A;  4QPF A;  4FP4 A;  4JYX A;  2ZEV A;  3RMG A;  3LOM A;  4KVI A;  4KVW A;  3G4D A;  3ZMB A;  1KIY A;  5I1U A;  3ZCD A;  3KRA A;  3SDU A;  1ZW5 A;  2F94 F;  3B7L A;  4LZ0 A;  3KRO A;  4XQS F;  2Z4X A;  4JXN A;  2I19 A;  5H9D A;  5CG5 A;  3PYB A;  1WL1 A;  4XQT F;  2E95 A;  3P8R A;  5AHU B;  4DWG A;  1EZF A;  5EAS A;  5B01 A;  4EA2 A;  3TC1 A;  2RAH A;  1WY0 A;  4H5C F;  2E92 A;  3V1X A;  4NFJ F;  3WCG A;  2H8O A;  4P0V A;  2F9K F;  3Q1O A;  1UBW A;  2ZCO A;  3QKC A;  3ICN A;  3WCH A;  3P5R A;  4NFI F;  1YHM A;  4RXE A;  5DGN F;  4F6V A;  3WC9 A;  2AZL A;  5IMI A;  3G4F A;  4P0X A;  2Z4V A;  3VJC A;  3VJB A;  3WCD A;  4DXJ A;  5JV0 F;  5HN8 A;  4RXC A;  3WCE A;  4Q23 A;  1WL3 A;  3N45 F;  2Q9Z A;  3IPI A;  5A0I A;  3AQB B;  5DHI A;  3NPR A;  3WSB A;  5IK9 A;  2E90 A;  5E8L A;  3TS7 A;  4KKM A;  2E94 A;  3WE9 A;  1V4H A;  2ZY1 A;  3MZV A;  3RYE A;  4H5D F;  3ACX A;  2Z52 A;  4LFV F;  4LTV A;  5IK6 A;  4LPH F;  5JV2 F;  5HNA A;  3WCM A;  3V66 A;  3KRP B;  3LEE A;  4MC3 A;  5ILZ A;  1WMW A;  5JV1 F;  4ZQ8 A;  2ZEU A;  2PS4 A;  4DHD A;  5IL3 A;  3S4J A;  1YJ4 A;  3N46 F;  2DH4 A;  3PKO A;  2P1C A;  3WCF A;  4OKM A;  1N21 A;  3P8L A;  5ILD A;  3N3D A;  4RXD A;  3AQ0 A;  2E93 A;  3ZOU A;  2Z4Z A;  3N6K F;  5B0J A;  2F8Z F;  5DJV F;  2E8U A;  3ICZ A;  1HX9 A;  4GA3 A;  3SDR A;  4LOB A;  4LUU A;  2F8C F;  4E9Z A;  3RYW A;  3WEI A;  4HD1 A;  4NKF A;  4F6X A;  4KPD A;  4KK2 A;  3KRP A;  4LA5 A;  3OAC B;  1RQJ A;  1DI1 A;  5DGM F;  1WKZ A;  4OGU A;  4K10 A;  2ONG A;  5IKA A;  1VG7 A;  5ILK A;  3WEG A;  2Z7H A;  2Z7I A;  5DJR F;  3TFN A;  3N5H F;  5ILY A;  4RNQ A;  1YYS A;  3VJE A;  1V4E A;  4JXY A;  5EAU A;  4KWD A;  2Z4Y A;  3AE0 A;  3TFV A;  4WK5 A;  1UBX A;  5IK0 A;  5HN9 A;  3M00 A;  5ERM A;  2J5C A;  4DI5 A;  4PVY F;  5ILI A;  4EA1 A;  5DIQ F;  2Z78 A;  3EZ3 A;  3ZMC A;  3KRF A;  1N1Z A;  1WL2 A;  1YV5 A;  5IMP A;  1YHL A;  1V4K A;  4F62 A;  4JZX A;  4DEM F;  5AEL A;  5B0I A;  2Z50 A;  3OAC A;  2AEL A;  3WJK A;  1YYT A;  4XQR F;  2F92 F;  4NKE A;  3KRC B;  2E8X A;  3EGT A;  3N3L F;  3OAB B;  4N9U A;  4UMJ A;  3P41 A;  2E8W A;  5ILH A;  5A0J A;  1WL0 A;  3NRI A;  3N5J F;  1UBV A;  3M9U A;  3N0G A;  3ACW A;  3AQC B;  5ER8 A;  5B00 A;  1YYQ A;  3LDW A;  5ILJ A;  1N24 A;  2ZCQ A;  4OMG A;  3P5P A;  3ZL6 A;  3M01 A;  5E8H A;  3N49 F;  3SDQ A;  3LK5 A;  1HM7 A;  5B02 A;  3CC9 A;  2QIS A;  3VJ8 A;  4QXS F;  5B0K A;  2AEK A;  3KRC A;  3VJA A; 
#chains in the Genus database with same CATH topology
 1DGP A;  3ICK A;  3DYH A;  5B03 A;  1N20 A;  3N0F A;  3S9V A;  4DWB A;  4LFG A;  1JFA A;  2AZK A;  3Q2Q A;  5IM1 A;  5C05 A;  4E1E A;  1FPS A;  5DW7 A;  3LSN A;  4LZC A;  5IN8 A;  5JUZ F;  4MC8 A;  3NF2 A;  3WCL A;  3KRA B;  4FJQ A;  3LGK A;  5DGS F;  3WEK A;  3LJI A;  4LLT A;  3MAV A;  3KRO B;  4LIX A;  2ONH A;  1YYR A;  3NPK A;  2E8V A;  3ICM A;  3VJ9 A;  3WEH A;  1YYU A;  3OYR A;  4GP2 A;  3WCI A;  4KUX A;  3WEJ A;  2PS6 A;  2ZCR A;  1VG6 A;  4MC0 A;  3LZ9 A;  5DHK A;  4OKZ A;  3CP6 A;  1V4I A;  2OA6 A;  2Z4W A;  5AYP A;  1HXC A;  2ZCS A;  4PVX F;  3N1V F;  2F89 F;  2E91 A;  2FOR A;  4GP1 A;  3QQV A;  4P0W A;  3SDV A;  5B0L A;  4N1Z F;  4KVD A;  4L2X F;  1PS1 A;  4LXW A;  3WCA A;  2J1P A;  1VG2 A;  5ERN A;  1V4J A;  1VG3 A;  4KQS A;  2OPM A;  3N1W F;  3WCJ A;  2OPN A;  5ERO A;  4RXA A;  5E8K A;  3M0G A;  3BNX A;  3RBM A;  3WEF A;  3M02 A;  4KQU A;  5IKH A;  4KQ5 A;  1YQ7 A;  2E4O A;  2F7M F;  4LFE A;  1N23 A;  3PYA A;  3WSA A;  3SDT A;  2PS5 A;  4RYP A;  1UBY A;  1JFG A;  3BNY A;  5DJP F;  4NG6 A;  1N22 A;  5B0M A;  4H5E F;  5IVG A;  3WCB A;  3KBK A;  2J1O A;  3LLW A;  4OMH A;  4JZB A;  3DYG A;  2EWG A;  5A0K A;  5EAT A;  3PDE A;  2FTZ A;  2Q80 A;  2PS8 A;  4KPJ A;  4LZ3 A;  2VF6 A;  4LA6 A;  5AFX A;  3SAE A;  2OGD A;  4E9U A;  4LPG F;  3DYF A;  3IBA A;  3OAB A;  3W7F A;  1HXA A;  2Q9Y A;  3WJO A;  4LLS A;  3ASX A;  4GAX A;  5IL8 A;  4JVJ F;  3KB9 A;  4DZW A;  5JA0 F;  3APZ A;  1RTR A;  4KVY A;  1N1B A;  3LVS A;  3PH7 A;  3LG5 A;  4EA0 A;  1RQI A;  2AZJ A;  5IMN A;  1VG4 A;  2PS7 A;  3ADZ A;  3V1V A;  3WJN A;  3UCA A;  2E8T A;  3Q30 A;  3LMD A;  2Q58 A;  3TFP A;  5KSX F;  5DZ2 A;  2O1O A;  2AET A;  1KIZ A;  3LGZ B;  3WCC A;  3Q2Z A;  5CG6 A;  1YHK A;  3KRF B;  4NUA A;  5HN7 A;  1HM4 A;  3ID0 A;  3VJD A;  3CKE A;  3EFQ A;  3ACY A;  4KFA A;  1HXG A;  4NFK F;  4LTZ A;  4QPF A;  4FP4 A;  4JYX A;  2ZEV A;  3RMG A;  3LOM A;  4KVI A;  4KVW A;  3G4D A;  3ZMB A;  1KIY A;  5I1U A;  3ZCD A;  3KRA A;  3SDU A;  1ZW5 A;  2F94 F;  3B7L A;  4LZ0 A;  3KRO A;  4XQS F;  2Z4X A;  4JXN A;  2I19 A;  5H9D A;  5CG5 A;  3PYB A;  1WL1 A;  4XQT F;  2E95 A;  3P8R A;  5AHU B;  4DWG A;  1EZF A;  5EAS A;  5B01 A;  4EA2 A;  3TC1 A;  2RAH A;  1WY0 A;  4H5C F;  2E92 A;  3V1X A;  4NFJ F;  3WCG A;  2H8O A;  4P0V A;  2F9K F;  3Q1O A;  1UBW A;  2ZCO A;  3QKC A;  3ICN A;  3WCH A;  3P5R A;  4NFI F;  1YHM A;  4RXE A;  5DGN F;  4F6V A;  3WC9 A;  2AZL A;  5IMI A;  3G4F A;  4P0X A;  2Z4V A;  3VJC A;  3VJB A;  3WCD A;  4DXJ A;  5JV0 F;  5HN8 A;  4RXC A;  3WCE A;  4Q23 A;  1WL3 A;  3N45 F;  2Q9Z A;  3IPI A;  5A0I A;  3AQB B;  5DHI A;  3NPR A;  3WSB A;  5IK9 A;  2E90 A;  5E8L A;  3TS7 A;  4KKM A;  2E94 A;  3WE9 A;  1V4H A;  2ZY1 A;  3MZV A;  3RYE A;  4H5D F;  3ACX A;  2Z52 A;  4LFV F;  4LTV A;  5IK6 A;  4LPH F;  5JV2 F;  5HNA A;  3WCM A;  3V66 A;  3KRP B;  3LEE A;  4MC3 A;  5ILZ A;  1WMW A;  5JV1 F;  4ZQ8 A;  2ZEU A;  2PS4 A;  4DHD A;  5IL3 A;  3S4J A;  1YJ4 A;  3N46 F;  2DH4 A;  3PKO A;  2P1C A;  3WCF A;  4OKM A;  1N21 A;  3P8L A;  5ILD A;  3N3D A;  4RXD A;  3AQ0 A;  2E93 A;  3ZOU A;  2Z4Z A;  3N6K F;  5B0J A;  2F8Z F;  5DJV F;  2E8U A;  3ICZ A;  1HX9 A;  4GA3 A;  3SDR A;  4LOB A;  4LUU A;  2F8C F;  4E9Z A;  3RYW A;  3WEI A;  4HD1 A;  4NKF A;  4F6X A;  4KPD A;  4KK2 A;  3KRP A;  4LA5 A;  3OAC B;  1RQJ A;  1DI1 A;  5DGM F;  1WKZ A;  4OGU A;  4K10 A;  2ONG A;  5IKA A;  1VG7 A;  5ILK A;  3WEG A;  2Z7H A;  2Z7I A;  5DJR F;  3TFN A;  3N5H F;  5ILY A;  4RNQ A;  1YYS A;  3VJE A;  1V4E A;  4JXY A;  5EAU A;  4KWD A;  2Z4Y A;  3AE0 A;  3TFV A;  4WK5 A;  1UBX A;  5IK0 A;  5HN9 A;  3M00 A;  5ERM A;  2J5C A;  4DI5 A;  4PVY F;  5ILI A;  4EA1 A;  5DIQ F;  2Z78 A;  3EZ3 A;  3ZMC A;  3KRF A;  1N1Z A;  1WL2 A;  1YV5 A;  5IMP A;  1YHL A;  1V4K A;  4F62 A;  4JZX A;  4DEM F;  5AEL A;  5B0I A;  2Z50 A;  3OAC A;  2AEL A;  3WJK A;  1YYT A;  4XQR F;  2F92 F;  4NKE A;  3KRC B;  2E8X A;  3EGT A;  3N3L F;  3OAB B;  4N9U A;  4UMJ A;  3P41 A;  2E8W A;  5ILH A;  5A0J A;  1WL0 A;  3NRI A;  3N5J F;  1UBV A;  3M9U A;  3N0G A;  3ACW A;  3AQC B;  5ER8 A;  5B00 A;  1YYQ A;  3LDW A;  5ILJ A;  1N24 A;  2ZCQ A;  4OMG A;  3P5P A;  3ZL6 A;  3M01 A;  5E8H A;  3N49 F;  3SDQ A;  3LK5 A;  1HM7 A;  5B02 A;  3CC9 A;  2QIS A;  3VJ8 A;  4QXS F;  5B0K A;  2AEK A;  3KRC A;  3VJA A; 
#chains in the Genus database with same CATH homology
 1DGP A;  3ICK A;  3DYH A;  5B03 A;  1N20 A;  3N0F A;  3S9V A;  4DWB A;  4LFG A;  1JFA A;  2AZK A;  3Q2Q A;  5IM1 A;  5C05 A;  4E1E A;  1FPS A;  5DW7 A;  3LSN A;  4LZC A;  5IN8 A;  5JUZ F;  4MC8 A;  3NF2 A;  3WCL A;  3KRA B;  4FJQ A;  3LGK A;  5DGS F;  3WEK A;  3LJI A;  4LLT A;  3MAV A;  3KRO B;  4LIX A;  2ONH A;  1YYR A;  3NPK A;  2E8V A;  3ICM A;  3VJ9 A;  3WEH A;  1YYU A;  3OYR A;  4GP2 A;  3WCI A;  4KUX A;  3WEJ A;  2PS6 A;  2ZCR A;  1VG6 A;  4MC0 A;  3LZ9 A;  5DHK A;  4OKZ A;  3CP6 A;  1V4I A;  2OA6 A;  2Z4W A;  5AYP A;  1HXC A;  2ZCS A;  4PVX F;  3N1V F;  2F89 F;  2E91 A;  2FOR A;  4GP1 A;  3QQV A;  4P0W A;  3SDV A;  5B0L A;  4N1Z F;  4KVD A;  4L2X F;  1PS1 A;  4LXW A;  3WCA A;  2J1P A;  1VG2 A;  5ERN A;  1V4J A;  1VG3 A;  4KQS A;  2OPM A;  3N1W F;  3WCJ A;  2OPN A;  5ERO A;  4RXA A;  5E8K A;  3M0G A;  3BNX A;  3RBM A;  3WEF A;  3M02 A;  4KQU A;  5IKH A;  4KQ5 A;  1YQ7 A;  2E4O A;  2F7M F;  4LFE A;  1N23 A;  3PYA A;  3WSA A;  3SDT A;  2PS5 A;  4RYP A;  1UBY A;  1JFG A;  3BNY A;  5DJP F;  4NG6 A;  1N22 A;  5B0M A;  4H5E F;  5IVG A;  3WCB A;  3KBK A;  2J1O A;  3LLW A;  4OMH A;  4JZB A;  3DYG A;  2EWG A;  5A0K A;  5EAT A;  3PDE A;  2FTZ A;  2Q80 A;  2PS8 A;  4KPJ A;  4LZ3 A;  2VF6 A;  4LA6 A;  5AFX A;  3SAE A;  2OGD A;  4E9U A;  4LPG F;  3DYF A;  3IBA A;  3OAB A;  3W7F A;  1HXA A;  2Q9Y A;  3WJO A;  4LLS A;  3ASX A;  4GAX A;  5IL8 A;  4JVJ F;  3KB9 A;  4DZW A;  5JA0 F;  3APZ A;  1RTR A;  4KVY A;  1N1B A;  3LVS A;  3PH7 A;  3LG5 A;  4EA0 A;  1RQI A;  2AZJ A;  5IMN A;  1VG4 A;  2PS7 A;  3ADZ A;  3V1V A;  3WJN A;  3UCA A;  2E8T A;  3Q30 A;  3LMD A;  2Q58 A;  3TFP A;  5KSX F;  5DZ2 A;  2O1O A;  2AET A;  1KIZ A;  3LGZ B;  3WCC A;  3Q2Z A;  5CG6 A;  1YHK A;  3KRF B;  4NUA A;  5HN7 A;  1HM4 A;  3ID0 A;  3VJD A;  3CKE A;  3EFQ A;  3ACY A;  4KFA A;  1HXG A;  4NFK F;  4LTZ A;  4QPF A;  4FP4 A;  4JYX A;  2ZEV A;  3RMG A;  3LOM A;  4KVI A;  4KVW A;  3G4D A;  3ZMB A;  1KIY A;  5I1U A;  3ZCD A;  3KRA A;  3SDU A;  1ZW5 A;  2F94 F;  3B7L A;  4LZ0 A;  3KRO A;  4XQS F;  2Z4X A;  4JXN A;  2I19 A;  5H9D A;  5CG5 A;  3PYB A;  1WL1 A;  4XQT F;  2E95 A;  3P8R A;  5AHU B;  4DWG A;  1EZF A;  5EAS A;  5B01 A;  4EA2 A;  3TC1 A;  2RAH A;  1WY0 A;  4H5C F;  2E92 A;  3V1X A;  4NFJ F;  3WCG A;  2H8O A;  4P0V A;  2F9K F;  3Q1O A;  1UBW A;  2ZCO A;  3QKC A;  3ICN A;  3WCH A;  3P5R A;  4NFI F;  1YHM A;  4RXE A;  5DGN F;  4F6V A;  3WC9 A;  2AZL A;  5IMI A;  3G4F A;  4P0X A;  2Z4V A;  3VJC A;  3VJB A;  3WCD A;  4DXJ A;  5JV0 F;  5HN8 A;  4RXC A;  3WCE A;  4Q23 A;  1WL3 A;  3N45 F;  2Q9Z A;  3IPI A;  5A0I A;  3AQB B;  5DHI A;  3NPR A;  3WSB A;  5IK9 A;  2E90 A;  5E8L A;  3TS7 A;  4KKM A;  2E94 A;  3WE9 A;  1V4H A;  2ZY1 A;  3MZV A;  3RYE A;  4H5D F;  3ACX A;  2Z52 A;  4LFV F;  4LTV A;  5IK6 A;  4LPH F;  5JV2 F;  5HNA A;  3WCM A;  3V66 A;  3KRP B;  3LEE A;  4MC3 A;  5ILZ A;  1WMW A;  5JV1 F;  4ZQ8 A;  2ZEU A;  2PS4 A;  4DHD A;  5IL3 A;  3S4J A;  1YJ4 A;  3N46 F;  2DH4 A;  3PKO A;  2P1C A;  3WCF A;  4OKM A;  1N21 A;  3P8L A;  5ILD A;  3N3D A;  4RXD A;  3AQ0 A;  2E93 A;  3ZOU A;  2Z4Z A;  3N6K F;  5B0J A;  2F8Z F;  5DJV F;  2E8U A;  3ICZ A;  1HX9 A;  4GA3 A;  3SDR A;  4LOB A;  4LUU A;  2F8C F;  4E9Z A;  3RYW A;  3WEI A;  4HD1 A;  4NKF A;  4F6X A;  4KPD A;  4KK2 A;  3KRP A;  4LA5 A;  3OAC B;  1RQJ A;  1DI1 A;  5DGM F;  1WKZ A;  4OGU A;  4K10 A;  2ONG A;  5IKA A;  1VG7 A;  5ILK A;  3WEG A;  2Z7H A;  2Z7I A;  5DJR F;  3TFN A;  3N5H F;  5ILY A;  4RNQ A;  1YYS A;  3VJE A;  1V4E A;  4JXY A;  5EAU A;  4KWD A;  2Z4Y A;  3AE0 A;  3TFV A;  4WK5 A;  1UBX A;  5IK0 A;  5HN9 A;  3M00 A;  5ERM A;  2J5C A;  4DI5 A;  4PVY F;  5ILI A;  4EA1 A;  5DIQ F;  2Z78 A;  3EZ3 A;  3ZMC A;  3KRF A;  1N1Z A;  1WL2 A;  1YV5 A;  5IMP A;  1YHL A;  1V4K A;  4F62 A;  4JZX A;  4DEM F;  5AEL A;  5B0I A;  2Z50 A;  3OAC A;  2AEL A;  3WJK A;  1YYT A;  4XQR F;  2F92 F;  4NKE A;  3KRC B;  2E8X A;  3EGT A;  3N3L F;  3OAB B;  4N9U A;  4UMJ A;  3P41 A;  2E8W A;  5ILH A;  5A0J A;  1WL0 A;  3NRI A;  3N5J F;  1UBV A;  3M9U A;  3N0G A;  3ACW A;  3AQC B;  5ER8 A;  5B00 A;  1YYQ A;  3LDW A;  5ILJ A;  1N24 A;  2ZCQ A;  4OMG A;  3P5P A;  3ZL6 A;  3M01 A;  5E8H A;  3N49 F;  3SDQ A;  3LK5 A;  1HM7 A;  5B02 A;  3CC9 A;  2QIS A;  3VJ8 A;  4QXS F;  5B0K A;  2AEK A;  3KRC A;  3VJA A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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