5JV0F

Crystal structure of human fpps in complex with an allosteric inhibitor cl-08-038
Total Genus 131
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
131
sequence length
343
structure length
341
Chain Sequence
DVYAQEKQDFVQHFSQIVRVLTEDEMGHPEIGDAIARLKEVLEYNAIGGKYNRGLTVVVAFRELVEPRKQDADSLQRAWTVGWCVELLQAFFLVADDIMDSSLTRRGQICWYQKPGVGLDAINDANLLEACIYRLLKLYCREQPYYLNLIELFLQSSYQTEIGQTLDLLTAPNVDLVRFTEKRYKSIVKYKTAFYSFYLPIAAAMYMAGIDGEKEHANAKKILLEMGEFFQIQDDYLDLFGDPSVTGKIGTDIQDNKCSWLVVQCLQRATPEQYQILKENYGQKEAEKVARVKALYEELDLPAVFLQYEEDSYSHIMALIEQYAAPLPPAVFLGLARKIYK
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Pharmacophore Mapping of Thienopyrimidine-Based Monophosphonate (ThP-MP) Inhibitors of the Human Farnesyl Pyrophosphate Synthase.
pubmed doi rcsb
molecule tags Transferase/transferase inhibitor
source organism Homo sapiens
molecule keywords Farnesyl pyrophosphate synthase
total genus 131
structure length 341
sequence length 343
ec nomenclature ec 2.5.1.1: Dimethylallyltranstransferase.
pdb deposition date 2016-05-10

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
F PF00348 polyprenyl_synt Polyprenyl synthetase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.600.10 Mainly Alpha Orthogonal Bundle Farnesyl Diphosphate Synthase Farnesyl Diphosphate Synthase 5jv0F00
3N0GA 2F94F 3UCAA 4F62A 4JXNA 2ZCRA 5DGSF 1YYQA 3EZ3A 3CKEA 4DEMF 3KRAA 3ICNA 1VG4A 3RYWA 3WCHA 3Q30A 1RTRA 1WKZA 5KSXF 3WEKA 3WCLA 4LPGF 3N5HF 4KK2A 3DYFA 5JV0F 3KRFB 5ILZA 4RXCA 2E91A 3ICKA 5EATA 4NFJF 5B00A 5HN7A 2OPMA 3V1VA 3AQ0A 3TFVA 4N1ZF 1YHKA 3N49F 4NFKF 4NKEA 2Z4WA 5IMNA 3TS7A 4QXSF 2J5CA 1WL1A 4E9UA 3KB9A 2Z78A 4EA1A 3ACWA 4PVYF 1WY0A 3NPKA 5B0JA 4P0VA 3P8LA 2E8TA 3WCIA 2P1CA 4LOBA 1YYTA 4KQUA 3MZVA 2OA6A 3NPRA 4MC8A 5DIQF 4GA3A 3N1VF 2PS5A 3WCDA 4EA2A 1RQJA 3SDQA 4NKFA 1WL0A 3VJCA 5JUZF 3LSNA 5ER8A 5DGNF 3WSBA 2Z50A 1HXAA 1WMWA 3P5PA 3WEIA 5IL3A 3EFQA 3LEEA 4KVIA 1DI1A 4KQSA 3LZ9A 4OKZA 1VG3A 5EASA 5AYPA 5A0IA 2Q9YA 2F92F 4DWBA 5IMPA 2Z4YA 2AZLA 1N23A 3WSAA 2ZEUA 1N21A 3SDRA 5IVGA 2E8VA 4DXJA 3ZMCA 3ADZA 3WEJA 5I1UA 1YHLA 2Q58A 1UBXA 3KROB 3OABB 2AELA 2PS7A 2ZCSA 3VJBA 4F6XA 3PH7A 3QQVA 2Z4VA 5IKAA 1UBYA 3N3DA 3IPIA 2E94A 4RYPA 5B01A 3KRCB 3OYRA 4KPJA 4LIXA 2E8XA 1YYSA 5B0MA 5B03A 4ZQ8A 1HX9A 3LLWA 3RBMA 3DYGA 4FP4A 2AZKA 3LOMA 1HXCA 4EA0A 4LA6A 3Q2QA 5JA0F 3ICMA 5DJVF 5B02A 2AEKA 4LFGA 1YHMA 2Z4ZA 4RXEA 1HM7A 3N1WF 3M0GA 5ERNA 4LZCA 3P41A 1V4JA 4P0XA 3P5RA 2ZCQA 1YJ4A 4LTVA 3VJAA 3WE9A 1N22A 4LUUA 4FJQA 3KRPB 5IL8A 1V4IA 4LLTA 5DJRF 1DGPA 2AZJA 3WCEA 5ILJA 3M02A 4KPDA 2E93A 4RNQA 2E95A 2F8ZF 4Q23A 3WCJA 4GP2A 2E8WA 4LFVF 1PS1A 2O1OA 3KRFA 3WCFA 3WEHA 3WJKA 1RQIA 2RAHA 3OACB 3PYAA 1ZW5A 4WK5A 4OGUA 4JYXA 3VJEA 1WL2A 1UBWA 4HD1A 1N1ZA 5DJPF 5B0KA 2FORA 5EROA 1HM4A 3PYBA 1YYUA 4KVDA 3S9VA 4E1EA 2Q9ZA 3N3LF 5CG5A 5JV1F 2E8UA 5H9DA 4RXDA 4DZWA 5E8HA 3DYHA 3MAVA 3Q1OA 5B0IA 2F9KF 5E8KA 5AHUB 1KIYA 2ONGA 4N9UA 4XQTF 2Z7HA 4NG6A 5DHIA 4XQRF 4KUXA 3G4DA 3AQBB 1UBVA 3M9UA 3WJNA 3SAEA 2OGDA 4MC3A 2H8OA 4KKMA 3N0FA 1N24A 3ZL6A 1N20A 1YYRA 3W7FA 4H5EF 3KBKA 3SDVA 3ICZA 1VG2A 3V66A 5ILHA 2Z4XA 2Z7IA 3N46F 4H5CF 3WC9A 3ZCDA 5AELA 2QISA 4JVJF 1KIZA 3KRAB 2PS6A 2E4OA 5HN8A 4LTZA 5AFXA 1N1BA 3RMGA 3KROA 4LZ0A 3ZOUA 4JZXA 5IN8A 3OABA 3TFPA 5A0KA 4GAXA 4KWDA 2F8CF 3LK5A 2Q80A 1FPSA 1V4EA 5IK6A 3ACXA 3M01A 3LG5A 5IKHA 3CP6A 1WL3A 1JFAA 4KFAA 3TFNA 3WEFA 4MC0A 5HNAA 4LFEA 5EAUA 3KRCA 3S4JA 4JZBA 1V4HA 3N5JF 5DZ2A 4NUAA 3G4FA 3ZMBA 2PS4A 1VG6A 4XQSF 3SDUA 5ILKA 3WJOA 4JXYA 3LVSA 4OKMA 4LPHF 5DGMF 2PS8A 2ONHA 5JV2F 3LGZB 1V4KA 3LDWA 3WCCA 3LMDA 5ILDA 4KVYA 3B7LA 3WCAA 3NF2A 3KRPA 3VJ8A 2VF6A 3N45F 4L2XF 3LJIA 3PKOA 2FTZA 4LA5A 3PDEA 5IK9A 4P0WA 2J1PA 3M00A 4PVXF 3TC1A 4H5DF 3VJ9A 3APZA 5ILYA 3WCBA 1YV5A 4KVWA 4OMHA 3OACA 2I19A 3V1XA 3Q2ZA 1JFGA 2ZCOA 2F89F 2J1OA 5IK0A 4E9ZA 4OMGA 3ID0A 5IMIA 4GP1A 4F6VA 2F7MF 4NFIF 4DHDA 4K10A 3CC9A 3IBAA 3WEGA 5ILIA 1HXGA 3AQCB 4DWGA 3EGTA 4UMJA 3WCGA 4RXAA 2ZY1A 3QKCA 2E90A 4LXWA 5A0JA 5E8LA 2AETA 4QPFA 1YQ7A 3AE0A 4KQ5A 4LZ3A 5ERMA 3SDTA 5HN9A 1VG7A 2OPNA 3RYEA 3BNYA 5IM1A 3ASXA 5C05A 2Z52A 2EWGA 5DW7A 3WCMA 5DHKA 2DH4A 2E92A 3BNXA 4LLSA 3VJDA 5B0LA 3N6KF 3LGKA 5CG6A 1EZFA 3ACYA 3P8RA 2ZEVA 3NRIA 4DI5A
chains in the Genus database with same CATH superfamily
3N0GA 2F94F 3UCAA 4F62A 4JXNA 2ZCRA 5DGSF 1YYQA 3EZ3A 3CKEA 4DEMF 3KRAA 3ICNA 1VG4A 3RYWA 3WCHA 3Q30A 1RTRA 1WKZA 5KSXF 3WEKA 3WCLA 4LPGF 3N5HF 4KK2A 3DYFA 5JV0F 3KRFB 5ILZA 4RXCA 2E91A 3ICKA 5EATA 4NFJF 5B00A 5HN7A 2OPMA 3V1VA 3AQ0A 3TFVA 4N1ZF 1YHKA 3N49F 4NFKF 4NKEA 2Z4WA 5IMNA 3TS7A 4QXSF 2J5CA 1WL1A 4E9UA 3KB9A 2Z78A 4EA1A 3ACWA 4PVYF 1WY0A 3NPKA 5B0JA 4P0VA 3P8LA 2E8TA 3WCIA 2P1CA 4LOBA 1YYTA 4KQUA 3MZVA 2OA6A 3NPRA 4MC8A 5DIQF 4GA3A 3N1VF 2PS5A 3WCDA 4EA2A 1RQJA 3SDQA 4NKFA 1WL0A 3VJCA 5JUZF 3LSNA 5ER8A 5DGNF 3WSBA 2Z50A 1HXAA 1WMWA 3P5PA 3WEIA 5IL3A 3EFQA 3LEEA 4KVIA 1DI1A 4KQSA 3LZ9A 4OKZA 1VG3A 5EASA 5AYPA 5A0IA 2Q9YA 2F92F 4DWBA 5IMPA 2Z4YA 2AZLA 1N23A 3WSAA 2ZEUA 1N21A 3SDRA 5IVGA 2E8VA 4DXJA 3ZMCA 3ADZA 3WEJA 5I1UA 1YHLA 2Q58A 1UBXA 3KROB 3OABB 2AELA 2PS7A 2ZCSA 3VJBA 4F6XA 3PH7A 3QQVA 2Z4VA 5IKAA 1UBYA 3N3DA 3IPIA 2E94A 4RYPA 5B01A 3KRCB 3OYRA 4KPJA 4LIXA 2E8XA 1YYSA 5B0MA 5B03A 4ZQ8A 1HX9A 3LLWA 3RBMA 3DYGA 4FP4A 2AZKA 3LOMA 1HXCA 4EA0A 4LA6A 3Q2QA 5JA0F 3ICMA 5DJVF 5B02A 2AEKA 4LFGA 1YHMA 2Z4ZA 4RXEA 1HM7A 3N1WF 3M0GA 5ERNA 4LZCA 3P41A 1V4JA 4P0XA 3P5RA 2ZCQA 1YJ4A 4LTVA 3VJAA 3WE9A 1N22A 4LUUA 4FJQA 3KRPB 5IL8A 1V4IA 4LLTA 5DJRF 1DGPA 2AZJA 3WCEA 5ILJA 3M02A 4KPDA 2E93A 4RNQA 2E95A 2F8ZF 4Q23A 3WCJA 4GP2A 2E8WA 4LFVF 1PS1A 2O1OA 3KRFA 3WCFA 3WEHA 3WJKA 1RQIA 2RAHA 3OACB 3PYAA 1ZW5A 4WK5A 4OGUA 4JYXA 3VJEA 1WL2A 1UBWA 4HD1A 1N1ZA 5DJPF 5B0KA 2FORA 5EROA 1HM4A 3PYBA 1YYUA 4KVDA 3S9VA 4E1EA 2Q9ZA 3N3LF 5CG5A 5JV1F 2E8UA 5H9DA 4RXDA 4DZWA 5E8HA 3DYHA 3MAVA 3Q1OA 5B0IA 2F9KF 5E8KA 5AHUB 1KIYA 2ONGA 4N9UA 4XQTF 2Z7HA 4NG6A 5DHIA 4XQRF 4KUXA 3G4DA 3AQBB 1UBVA 3M9UA 3WJNA 3SAEA 2OGDA 4MC3A 2H8OA 4KKMA 3N0FA 1N24A 3ZL6A 1N20A 1YYRA 3W7FA 4H5EF 3KBKA 3SDVA 3ICZA 1VG2A 3V66A 5ILHA 2Z4XA 2Z7IA 3N46F 4H5CF 3WC9A 3ZCDA 5AELA 2QISA 4JVJF 1KIZA 3KRAB 2PS6A 2E4OA 5HN8A 4LTZA 5AFXA 1N1BA 3RMGA 3KROA 4LZ0A 3ZOUA 4JZXA 5IN8A 3OABA 3TFPA 5A0KA 4GAXA 4KWDA 2F8CF 3LK5A 2Q80A 1FPSA 1V4EA 5IK6A 3ACXA 3M01A 3LG5A 5IKHA 3CP6A 1WL3A 1JFAA 4KFAA 3TFNA 3WEFA 4MC0A 5HNAA 4LFEA 5EAUA 3KRCA 3S4JA 4JZBA 1V4HA 3N5JF 5DZ2A 4NUAA 3G4FA 3ZMBA 2PS4A 1VG6A 4XQSF 3SDUA 5ILKA 3WJOA 4JXYA 3LVSA 4OKMA 4LPHF 5DGMF 2PS8A 2ONHA 5JV2F 3LGZB 1V4KA 3LDWA 3WCCA 3LMDA 5ILDA 4KVYA 3B7LA 3WCAA 3NF2A 3KRPA 3VJ8A 2VF6A 3N45F 4L2XF 3LJIA 3PKOA 2FTZA 4LA5A 3PDEA 5IK9A 4P0WA 2J1PA 3M00A 4PVXF 3TC1A 4H5DF 3VJ9A 3APZA 5ILYA 3WCBA 1YV5A 4KVWA 4OMHA 3OACA 2I19A 3V1XA 3Q2ZA 1JFGA 2ZCOA 2F89F 2J1OA 5IK0A 4E9ZA 4OMGA 3ID0A 5IMIA 4GP1A 4F6VA 2F7MF 4NFIF 4DHDA 4K10A 3CC9A 3IBAA 3WEGA 5ILIA 1HXGA 3AQCB 4DWGA 3EGTA 4UMJA 3WCGA 4RXAA 2ZY1A 3QKCA 2E90A 4LXWA 5A0JA 5E8LA 2AETA 4QPFA 1YQ7A 3AE0A 4KQ5A 4LZ3A 5ERMA 3SDTA 5HN9A 1VG7A 2OPNA 3RYEA 3BNYA 5IM1A 3ASXA 5C05A 2Z52A 2EWGA 5DW7A 3WCMA 5DHKA 2DH4A 2E92A 3BNXA 4LLSA 3VJDA 5B0LA 3N6KF 3LGKA 5CG6A 1EZFA 3ACYA 3P8RA 2ZEVA 3NRIA 4DI5A
chains in the Genus database with same CATH topology
3N0GA 2F94F 3UCAA 4F62A 4JXNA 2ZCRA 5DGSF 1YYQA 3EZ3A 3CKEA 4DEMF 3KRAA 3ICNA 1VG4A 3RYWA 3WCHA 3Q30A 1RTRA 1WKZA 5KSXF 3WEKA 3WCLA 4LPGF 3N5HF 4KK2A 3DYFA 5JV0F 3KRFB 5ILZA 4RXCA 2E91A 3ICKA 5EATA 4NFJF 5B00A 5HN7A 2OPMA 3V1VA 3AQ0A 3TFVA 4N1ZF 1YHKA 3N49F 4NFKF 4NKEA 2Z4WA 5IMNA 3TS7A 4QXSF 2J5CA 1WL1A 4E9UA 3KB9A 2Z78A 4EA1A 3ACWA 4PVYF 1WY0A 3NPKA 5B0JA 4P0VA 3P8LA 2E8TA 3WCIA 2P1CA 4LOBA 1YYTA 4KQUA 3MZVA 2OA6A 3NPRA 4MC8A 5DIQF 4GA3A 3N1VF 2PS5A 3WCDA 4EA2A 1RQJA 3SDQA 4NKFA 1WL0A 3VJCA 5JUZF 3LSNA 5ER8A 5DGNF 3WSBA 2Z50A 1HXAA 1WMWA 3P5PA 3WEIA 5IL3A 3EFQA 3LEEA 4KVIA 1DI1A 4KQSA 3LZ9A 4OKZA 1VG3A 5EASA 5AYPA 5A0IA 2Q9YA 2F92F 4DWBA 5IMPA 2Z4YA 2AZLA 1N23A 3WSAA 2ZEUA 1N21A 3SDRA 5IVGA 2E8VA 4DXJA 3ZMCA 3ADZA 3WEJA 5I1UA 1YHLA 2Q58A 1UBXA 3KROB 3OABB 2AELA 2PS7A 2ZCSA 3VJBA 4F6XA 3PH7A 3QQVA 2Z4VA 5IKAA 1UBYA 3N3DA 3IPIA 2E94A 4RYPA 5B01A 3KRCB 3OYRA 4KPJA 4LIXA 2E8XA 1YYSA 5B0MA 5B03A 4ZQ8A 1HX9A 3LLWA 3RBMA 3DYGA 4FP4A 2AZKA 3LOMA 1HXCA 4EA0A 4LA6A 3Q2QA 5JA0F 3ICMA 5DJVF 5B02A 2AEKA 4LFGA 1YHMA 2Z4ZA 4RXEA 1HM7A 3N1WF 3M0GA 5ERNA 4LZCA 3P41A 1V4JA 4P0XA 3P5RA 2ZCQA 1YJ4A 4LTVA 3VJAA 3WE9A 1N22A 4LUUA 4FJQA 3KRPB 5IL8A 1V4IA 4LLTA 5DJRF 1DGPA 2AZJA 3WCEA 5ILJA 3M02A 4KPDA 2E93A 4RNQA 2E95A 2F8ZF 4Q23A 3WCJA 4GP2A 2E8WA 4LFVF 1PS1A 2O1OA 3KRFA 3WCFA 3WEHA 3WJKA 1RQIA 2RAHA 3OACB 3PYAA 1ZW5A 4WK5A 4OGUA 4JYXA 3VJEA 1WL2A 1UBWA 4HD1A 1N1ZA 5DJPF 5B0KA 2FORA 5EROA 1HM4A 3PYBA 1YYUA 4KVDA 3S9VA 4E1EA 2Q9ZA 3N3LF 5CG5A 5JV1F 2E8UA 5H9DA 4RXDA 4DZWA 5E8HA 3DYHA 3MAVA 3Q1OA 5B0IA 2F9KF 5E8KA 5AHUB 1KIYA 2ONGA 4N9UA 4XQTF 2Z7HA 4NG6A 5DHIA 4XQRF 4KUXA 3G4DA 3AQBB 1UBVA 3M9UA 3WJNA 3SAEA 2OGDA 4MC3A 2H8OA 4KKMA 3N0FA 1N24A 3ZL6A 1N20A 1YYRA 3W7FA 4H5EF 3KBKA 3SDVA 3ICZA 1VG2A 3V66A 5ILHA 2Z4XA 2Z7IA 3N46F 4H5CF 3WC9A 3ZCDA 5AELA 2QISA 4JVJF 1KIZA 3KRAB 2PS6A 2E4OA 5HN8A 4LTZA 5AFXA 1N1BA 3RMGA 3KROA 4LZ0A 3ZOUA 4JZXA 5IN8A 3OABA 3TFPA 5A0KA 4GAXA 4KWDA 2F8CF 3LK5A 2Q80A 1FPSA 1V4EA 5IK6A 3ACXA 3M01A 3LG5A 5IKHA 3CP6A 1WL3A 1JFAA 4KFAA 3TFNA 3WEFA 4MC0A 5HNAA 4LFEA 5EAUA 3KRCA 3S4JA 4JZBA 1V4HA 3N5JF 5DZ2A 4NUAA 3G4FA 3ZMBA 2PS4A 1VG6A 4XQSF 3SDUA 5ILKA 3WJOA 4JXYA 3LVSA 4OKMA 4LPHF 5DGMF 2PS8A 2ONHA 5JV2F 3LGZB 1V4KA 3LDWA 3WCCA 3LMDA 5ILDA 4KVYA 3B7LA 3WCAA 3NF2A 3KRPA 3VJ8A 2VF6A 3N45F 4L2XF 3LJIA 3PKOA 2FTZA 4LA5A 3PDEA 5IK9A 4P0WA 2J1PA 3M00A 4PVXF 3TC1A 4H5DF 3VJ9A 3APZA 5ILYA 3WCBA 1YV5A 4KVWA 4OMHA 3OACA 2I19A 3V1XA 3Q2ZA 1JFGA 2ZCOA 2F89F 2J1OA 5IK0A 4E9ZA 4OMGA 3ID0A 5IMIA 4GP1A 4F6VA 2F7MF 4NFIF 4DHDA 4K10A 3CC9A 3IBAA 3WEGA 5ILIA 1HXGA 3AQCB 4DWGA 3EGTA 4UMJA 3WCGA 4RXAA 2ZY1A 3QKCA 2E90A 4LXWA 5A0JA 5E8LA 2AETA 4QPFA 1YQ7A 3AE0A 4KQ5A 4LZ3A 5ERMA 3SDTA 5HN9A 1VG7A 2OPNA 3RYEA 3BNYA 5IM1A 3ASXA 5C05A 2Z52A 2EWGA 5DW7A 3WCMA 5DHKA 2DH4A 2E92A 3BNXA 4LLSA 3VJDA 5B0LA 3N6KF 3LGKA 5CG6A 1EZFA 3ACYA 3P8RA 2ZEVA 3NRIA 4DI5A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3N0G A;  2F94 F;  3UCA A;  4F62 A;  4JXN A;  2ZCR A;  5DGS F;  1YYQ A;  3EZ3 A;  3CKE A;  4DEM F;  3KRA A;  3ICN A;  1VG4 A;  3RYW A;  3WCH A;  3Q30 A;  1RTR A;  1WKZ A;  5KSX F;  3WEK A;  3WCL A;  4LPG F;  3N5H F;  4KK2 A;  3DYF A;  5JV0 F;  3KRF B;  5ILZ A;  4RXC A;  2E91 A;  3ICK A;  5EAT A;  4NFJ F;  5B00 A;  5HN7 A;  2OPM A;  3V1V A;  3AQ0 A;  3TFV A;  4N1Z F;  1YHK A;  3N49 F;  4NFK F;  4NKE A;  2Z4W A;  5IMN A;  3TS7 A;  4QXS F;  2J5C A;  1WL1 A;  4E9U A;  3KB9 A;  2Z78 A;  4EA1 A;  3ACW A;  4PVY F;  1WY0 A;  3NPK A;  5B0J A;  4P0V A;  3P8L A;  2E8T A;  3WCI A;  2P1C A;  4LOB A;  1YYT A;  4KQU A;  3MZV A;  2OA6 A;  3NPR A;  4MC8 A;  5DIQ F;  4GA3 A;  3N1V F;  2PS5 A;  3WCD A;  4EA2 A;  1RQJ A;  3SDQ A;  4NKF A;  1WL0 A;  3VJC A;  5JUZ F;  3LSN A;  5ER8 A;  5DGN F;  3WSB A;  2Z50 A;  1HXA A;  1WMW A;  3P5P A;  3WEI A;  5IL3 A;  3EFQ A;  3LEE A;  4KVI A;  1DI1 A;  4KQS A;  3LZ9 A;  4OKZ A;  1VG3 A;  5EAS A;  5AYP A;  5A0I A;  2Q9Y A;  2F92 F;  4DWB A;  5IMP A;  2Z4Y A;  2AZL A;  1N23 A;  3WSA A;  2ZEU A;  1N21 A;  3SDR A;  5IVG A;  2E8V A;  4DXJ A;  3ZMC A;  3ADZ A;  3WEJ A;  5I1U A;  1YHL A;  2Q58 A;  1UBX A;  3KRO B;  3OAB B;  2AEL A;  2PS7 A;  2ZCS A;  3VJB A;  4F6X A;  3PH7 A;  3QQV A;  2Z4V A;  5IKA A;  1UBY A;  3N3D A;  3IPI A;  2E94 A;  4RYP A;  5B01 A;  3KRC B;  3OYR A;  4KPJ A;  4LIX A;  2E8X A;  1YYS A;  5B0M A;  5B03 A;  4ZQ8 A;  1HX9 A;  3LLW A;  3RBM A;  3DYG A;  4FP4 A;  2AZK A;  3LOM A;  1HXC A;  4EA0 A;  4LA6 A;  3Q2Q A;  5JA0 F;  3ICM A;  5DJV F;  5B02 A;  2AEK A;  4LFG A;  1YHM A;  2Z4Z A;  4RXE A;  1HM7 A;  3N1W F;  3M0G A;  5ERN A;  4LZC A;  3P41 A;  1V4J A;  4P0X A;  3P5R A;  2ZCQ A;  1YJ4 A;  4LTV A;  3VJA A;  3WE9 A;  1N22 A;  4LUU A;  4FJQ A;  3KRP B;  5IL8 A;  1V4I A;  4LLT A;  5DJR F;  1DGP A;  2AZJ A;  3WCE A;  5ILJ A;  3M02 A;  4KPD A;  2E93 A;  4RNQ A;  2E95 A;  2F8Z F;  4Q23 A;  3WCJ A;  4GP2 A;  2E8W A;  4LFV F;  1PS1 A;  2O1O A;  3KRF A;  3WCF A;  3WEH A;  3WJK A;  1RQI A;  2RAH A;  3OAC B;  3PYA A;  1ZW5 A;  4WK5 A;  4OGU A;  4JYX A;  3VJE A;  1WL2 A;  1UBW A;  4HD1 A;  1N1Z A;  5DJP F;  5B0K A;  2FOR A;  5ERO A;  1HM4 A;  3PYB A;  1YYU A;  4KVD A;  3S9V A;  4E1E A;  2Q9Z A;  3N3L F;  5CG5 A;  5JV1 F;  2E8U A;  5H9D A;  4RXD A;  4DZW A;  5E8H A;  3DYH A;  3MAV A;  3Q1O A;  5B0I A;  2F9K F;  5E8K A;  5AHU B;  1KIY A;  2ONG A;  4N9U A;  4XQT F;  2Z7H A;  4NG6 A;  5DHI A;  4XQR F;  4KUX A;  3G4D A;  3AQB B;  1UBV A;  3M9U A;  3WJN A;  3SAE A;  2OGD A;  4MC3 A;  2H8O A;  4KKM A;  3N0F A;  1N24 A;  3ZL6 A;  1N20 A;  1YYR A;  3W7F A;  4H5E F;  3KBK A;  3SDV A;  3ICZ A;  1VG2 A;  3V66 A;  5ILH A;  2Z4X A;  2Z7I A;  3N46 F;  4H5C F;  3WC9 A;  3ZCD A;  5AEL A;  2QIS A;  4JVJ F;  1KIZ A;  3KRA B;  2PS6 A;  2E4O A;  5HN8 A;  4LTZ A;  5AFX A;  1N1B A;  3RMG A;  3KRO A;  4LZ0 A;  3ZOU A;  4JZX A;  5IN8 A;  3OAB A;  3TFP A;  5A0K A;  4GAX A;  4KWD A;  2F8C F;  3LK5 A;  2Q80 A;  1FPS A;  1V4E A;  5IK6 A;  3ACX A;  3M01 A;  3LG5 A;  5IKH A;  3CP6 A;  1WL3 A;  1JFA A;  4KFA A;  3TFN A;  3WEF A;  4MC0 A;  5HNA A;  4LFE A;  5EAU A;  3KRC A;  3S4J A;  4JZB A;  1V4H A;  3N5J F;  5DZ2 A;  4NUA A;  3G4F A;  3ZMB A;  2PS4 A;  1VG6 A;  4XQS F;  3SDU A;  5ILK A;  3WJO A;  4JXY A;  3LVS A;  4OKM A;  4LPH F;  5DGM F;  2PS8 A;  2ONH A;  5JV2 F;  3LGZ B;  1V4K A;  3LDW A;  3WCC A;  3LMD A;  5ILD A;  4KVY A;  3B7L A;  3WCA A;  3NF2 A;  3KRP A;  3VJ8 A;  2VF6 A;  3N45 F;  4L2X F;  3LJI A;  3PKO A;  2FTZ A;  4LA5 A;  3PDE A;  5IK9 A;  4P0W A;  2J1P A;  3M00 A;  4PVX F;  3TC1 A;  4H5D F;  3VJ9 A;  3APZ A;  5ILY A;  3WCB A;  1YV5 A;  4KVW A;  4OMH A;  3OAC A;  2I19 A;  3V1X A;  3Q2Z A;  1JFG A;  2ZCO A;  2F89 F;  2J1O A;  5IK0 A;  4E9Z A;  4OMG A;  3ID0 A;  5IMI A;  4GP1 A;  4F6V A;  2F7M F;  4NFI F;  4DHD A;  4K10 A;  3CC9 A;  3IBA A;  3WEG A;  5ILI A;  1HXG A;  3AQC B;  4DWG A;  3EGT A;  4UMJ A;  3WCG A;  4RXA A;  2ZY1 A;  3QKC A;  2E90 A;  4LXW A;  5A0J A;  5E8L A;  2AET A;  4QPF A;  1YQ7 A;  3AE0 A;  4KQ5 A;  4LZ3 A;  5ERM A;  3SDT A;  5HN9 A;  1VG7 A;  2OPN A;  3RYE A;  3BNY A;  5IM1 A;  3ASX A;  5C05 A;  2Z52 A;  2EWG A;  5DW7 A;  3WCM A;  5DHK A;  2DH4 A;  2E92 A;  3BNX A;  4LLS A;  3VJD A;  5B0L A;  3N6K F;  3LGK A;  5CG6 A;  1EZF A;  3ACY A;  3P8R A;  2ZEV A;  3NRI A;  4DI5 A; 
#chains in the Genus database with same CATH topology
 3N0G A;  2F94 F;  3UCA A;  4F62 A;  4JXN A;  2ZCR A;  5DGS F;  1YYQ A;  3EZ3 A;  3CKE A;  4DEM F;  3KRA A;  3ICN A;  1VG4 A;  3RYW A;  3WCH A;  3Q30 A;  1RTR A;  1WKZ A;  5KSX F;  3WEK A;  3WCL A;  4LPG F;  3N5H F;  4KK2 A;  3DYF A;  5JV0 F;  3KRF B;  5ILZ A;  4RXC A;  2E91 A;  3ICK A;  5EAT A;  4NFJ F;  5B00 A;  5HN7 A;  2OPM A;  3V1V A;  3AQ0 A;  3TFV A;  4N1Z F;  1YHK A;  3N49 F;  4NFK F;  4NKE A;  2Z4W A;  5IMN A;  3TS7 A;  4QXS F;  2J5C A;  1WL1 A;  4E9U A;  3KB9 A;  2Z78 A;  4EA1 A;  3ACW A;  4PVY F;  1WY0 A;  3NPK A;  5B0J A;  4P0V A;  3P8L A;  2E8T A;  3WCI A;  2P1C A;  4LOB A;  1YYT A;  4KQU A;  3MZV A;  2OA6 A;  3NPR A;  4MC8 A;  5DIQ F;  4GA3 A;  3N1V F;  2PS5 A;  3WCD A;  4EA2 A;  1RQJ A;  3SDQ A;  4NKF A;  1WL0 A;  3VJC A;  5JUZ F;  3LSN A;  5ER8 A;  5DGN F;  3WSB A;  2Z50 A;  1HXA A;  1WMW A;  3P5P A;  3WEI A;  5IL3 A;  3EFQ A;  3LEE A;  4KVI A;  1DI1 A;  4KQS A;  3LZ9 A;  4OKZ A;  1VG3 A;  5EAS A;  5AYP A;  5A0I A;  2Q9Y A;  2F92 F;  4DWB A;  5IMP A;  2Z4Y A;  2AZL A;  1N23 A;  3WSA A;  2ZEU A;  1N21 A;  3SDR A;  5IVG A;  2E8V A;  4DXJ A;  3ZMC A;  3ADZ A;  3WEJ A;  5I1U A;  1YHL A;  2Q58 A;  1UBX A;  3KRO B;  3OAB B;  2AEL A;  2PS7 A;  2ZCS A;  3VJB A;  4F6X A;  3PH7 A;  3QQV A;  2Z4V A;  5IKA A;  1UBY A;  3N3D A;  3IPI A;  2E94 A;  4RYP A;  5B01 A;  3KRC B;  3OYR A;  4KPJ A;  4LIX A;  2E8X A;  1YYS A;  5B0M A;  5B03 A;  4ZQ8 A;  1HX9 A;  3LLW A;  3RBM A;  3DYG A;  4FP4 A;  2AZK A;  3LOM A;  1HXC A;  4EA0 A;  4LA6 A;  3Q2Q A;  5JA0 F;  3ICM A;  5DJV F;  5B02 A;  2AEK A;  4LFG A;  1YHM A;  2Z4Z A;  4RXE A;  1HM7 A;  3N1W F;  3M0G A;  5ERN A;  4LZC A;  3P41 A;  1V4J A;  4P0X A;  3P5R A;  2ZCQ A;  1YJ4 A;  4LTV A;  3VJA A;  3WE9 A;  1N22 A;  4LUU A;  4FJQ A;  3KRP B;  5IL8 A;  1V4I A;  4LLT A;  5DJR F;  1DGP A;  2AZJ A;  3WCE A;  5ILJ A;  3M02 A;  4KPD A;  2E93 A;  4RNQ A;  2E95 A;  2F8Z F;  4Q23 A;  3WCJ A;  4GP2 A;  2E8W A;  4LFV F;  1PS1 A;  2O1O A;  3KRF A;  3WCF A;  3WEH A;  3WJK A;  1RQI A;  2RAH A;  3OAC B;  3PYA A;  1ZW5 A;  4WK5 A;  4OGU A;  4JYX A;  3VJE A;  1WL2 A;  1UBW A;  4HD1 A;  1N1Z A;  5DJP F;  5B0K A;  2FOR A;  5ERO A;  1HM4 A;  3PYB A;  1YYU A;  4KVD A;  3S9V A;  4E1E A;  2Q9Z A;  3N3L F;  5CG5 A;  5JV1 F;  2E8U A;  5H9D A;  4RXD A;  4DZW A;  5E8H A;  3DYH A;  3MAV A;  3Q1O A;  5B0I A;  2F9K F;  5E8K A;  5AHU B;  1KIY A;  2ONG A;  4N9U A;  4XQT F;  2Z7H A;  4NG6 A;  5DHI A;  4XQR F;  4KUX A;  3G4D A;  3AQB B;  1UBV A;  3M9U A;  3WJN A;  3SAE A;  2OGD A;  4MC3 A;  2H8O A;  4KKM A;  3N0F A;  1N24 A;  3ZL6 A;  1N20 A;  1YYR A;  3W7F A;  4H5E F;  3KBK A;  3SDV A;  3ICZ A;  1VG2 A;  3V66 A;  5ILH A;  2Z4X A;  2Z7I A;  3N46 F;  4H5C F;  3WC9 A;  3ZCD A;  5AEL A;  2QIS A;  4JVJ F;  1KIZ A;  3KRA B;  2PS6 A;  2E4O A;  5HN8 A;  4LTZ A;  5AFX A;  1N1B A;  3RMG A;  3KRO A;  4LZ0 A;  3ZOU A;  4JZX A;  5IN8 A;  3OAB A;  3TFP A;  5A0K A;  4GAX A;  4KWD A;  2F8C F;  3LK5 A;  2Q80 A;  1FPS A;  1V4E A;  5IK6 A;  3ACX A;  3M01 A;  3LG5 A;  5IKH A;  3CP6 A;  1WL3 A;  1JFA A;  4KFA A;  3TFN A;  3WEF A;  4MC0 A;  5HNA A;  4LFE A;  5EAU A;  3KRC A;  3S4J A;  4JZB A;  1V4H A;  3N5J F;  5DZ2 A;  4NUA A;  3G4F A;  3ZMB A;  2PS4 A;  1VG6 A;  4XQS F;  3SDU A;  5ILK A;  3WJO A;  4JXY A;  3LVS A;  4OKM A;  4LPH F;  5DGM F;  2PS8 A;  2ONH A;  5JV2 F;  3LGZ B;  1V4K A;  3LDW A;  3WCC A;  3LMD A;  5ILD A;  4KVY A;  3B7L A;  3WCA A;  3NF2 A;  3KRP A;  3VJ8 A;  2VF6 A;  3N45 F;  4L2X F;  3LJI A;  3PKO A;  2FTZ A;  4LA5 A;  3PDE A;  5IK9 A;  4P0W A;  2J1P A;  3M00 A;  4PVX F;  3TC1 A;  4H5D F;  3VJ9 A;  3APZ A;  5ILY A;  3WCB A;  1YV5 A;  4KVW A;  4OMH A;  3OAC A;  2I19 A;  3V1X A;  3Q2Z A;  1JFG A;  2ZCO A;  2F89 F;  2J1O A;  5IK0 A;  4E9Z A;  4OMG A;  3ID0 A;  5IMI A;  4GP1 A;  4F6V A;  2F7M F;  4NFI F;  4DHD A;  4K10 A;  3CC9 A;  3IBA A;  3WEG A;  5ILI A;  1HXG A;  3AQC B;  4DWG A;  3EGT A;  4UMJ A;  3WCG A;  4RXA A;  2ZY1 A;  3QKC A;  2E90 A;  4LXW A;  5A0J A;  5E8L A;  2AET A;  4QPF A;  1YQ7 A;  3AE0 A;  4KQ5 A;  4LZ3 A;  5ERM A;  3SDT A;  5HN9 A;  1VG7 A;  2OPN A;  3RYE A;  3BNY A;  5IM1 A;  3ASX A;  5C05 A;  2Z52 A;  2EWG A;  5DW7 A;  3WCM A;  5DHK A;  2DH4 A;  2E92 A;  3BNX A;  4LLS A;  3VJD A;  5B0L A;  3N6K F;  3LGK A;  5CG6 A;  1EZF A;  3ACY A;  3P8R A;  2ZEV A;  3NRI A;  4DI5 A; 
#chains in the Genus database with same CATH homology
 3N0G A;  2F94 F;  3UCA A;  4F62 A;  4JXN A;  2ZCR A;  5DGS F;  1YYQ A;  3EZ3 A;  3CKE A;  4DEM F;  3KRA A;  3ICN A;  1VG4 A;  3RYW A;  3WCH A;  3Q30 A;  1RTR A;  1WKZ A;  5KSX F;  3WEK A;  3WCL A;  4LPG F;  3N5H F;  4KK2 A;  3DYF A;  5JV0 F;  3KRF B;  5ILZ A;  4RXC A;  2E91 A;  3ICK A;  5EAT A;  4NFJ F;  5B00 A;  5HN7 A;  2OPM A;  3V1V A;  3AQ0 A;  3TFV A;  4N1Z F;  1YHK A;  3N49 F;  4NFK F;  4NKE A;  2Z4W A;  5IMN A;  3TS7 A;  4QXS F;  2J5C A;  1WL1 A;  4E9U A;  3KB9 A;  2Z78 A;  4EA1 A;  3ACW A;  4PVY F;  1WY0 A;  3NPK A;  5B0J A;  4P0V A;  3P8L A;  2E8T A;  3WCI A;  2P1C A;  4LOB A;  1YYT A;  4KQU A;  3MZV A;  2OA6 A;  3NPR A;  4MC8 A;  5DIQ F;  4GA3 A;  3N1V F;  2PS5 A;  3WCD A;  4EA2 A;  1RQJ A;  3SDQ A;  4NKF A;  1WL0 A;  3VJC A;  5JUZ F;  3LSN A;  5ER8 A;  5DGN F;  3WSB A;  2Z50 A;  1HXA A;  1WMW A;  3P5P A;  3WEI A;  5IL3 A;  3EFQ A;  3LEE A;  4KVI A;  1DI1 A;  4KQS A;  3LZ9 A;  4OKZ A;  1VG3 A;  5EAS A;  5AYP A;  5A0I A;  2Q9Y A;  2F92 F;  4DWB A;  5IMP A;  2Z4Y A;  2AZL A;  1N23 A;  3WSA A;  2ZEU A;  1N21 A;  3SDR A;  5IVG A;  2E8V A;  4DXJ A;  3ZMC A;  3ADZ A;  3WEJ A;  5I1U A;  1YHL A;  2Q58 A;  1UBX A;  3KRO B;  3OAB B;  2AEL A;  2PS7 A;  2ZCS A;  3VJB A;  4F6X A;  3PH7 A;  3QQV A;  2Z4V A;  5IKA A;  1UBY A;  3N3D A;  3IPI A;  2E94 A;  4RYP A;  5B01 A;  3KRC B;  3OYR A;  4KPJ A;  4LIX A;  2E8X A;  1YYS A;  5B0M A;  5B03 A;  4ZQ8 A;  1HX9 A;  3LLW A;  3RBM A;  3DYG A;  4FP4 A;  2AZK A;  3LOM A;  1HXC A;  4EA0 A;  4LA6 A;  3Q2Q A;  5JA0 F;  3ICM A;  5DJV F;  5B02 A;  2AEK A;  4LFG A;  1YHM A;  2Z4Z A;  4RXE A;  1HM7 A;  3N1W F;  3M0G A;  5ERN A;  4LZC A;  3P41 A;  1V4J A;  4P0X A;  3P5R A;  2ZCQ A;  1YJ4 A;  4LTV A;  3VJA A;  3WE9 A;  1N22 A;  4LUU A;  4FJQ A;  3KRP B;  5IL8 A;  1V4I A;  4LLT A;  5DJR F;  1DGP A;  2AZJ A;  3WCE A;  5ILJ A;  3M02 A;  4KPD A;  2E93 A;  4RNQ A;  2E95 A;  2F8Z F;  4Q23 A;  3WCJ A;  4GP2 A;  2E8W A;  4LFV F;  1PS1 A;  2O1O A;  3KRF A;  3WCF A;  3WEH A;  3WJK A;  1RQI A;  2RAH A;  3OAC B;  3PYA A;  1ZW5 A;  4WK5 A;  4OGU A;  4JYX A;  3VJE A;  1WL2 A;  1UBW A;  4HD1 A;  1N1Z A;  5DJP F;  5B0K A;  2FOR A;  5ERO A;  1HM4 A;  3PYB A;  1YYU A;  4KVD A;  3S9V A;  4E1E A;  2Q9Z A;  3N3L F;  5CG5 A;  5JV1 F;  2E8U A;  5H9D A;  4RXD A;  4DZW A;  5E8H A;  3DYH A;  3MAV A;  3Q1O A;  5B0I A;  2F9K F;  5E8K A;  5AHU B;  1KIY A;  2ONG A;  4N9U A;  4XQT F;  2Z7H A;  4NG6 A;  5DHI A;  4XQR F;  4KUX A;  3G4D A;  3AQB B;  1UBV A;  3M9U A;  3WJN A;  3SAE A;  2OGD A;  4MC3 A;  2H8O A;  4KKM A;  3N0F A;  1N24 A;  3ZL6 A;  1N20 A;  1YYR A;  3W7F A;  4H5E F;  3KBK A;  3SDV A;  3ICZ A;  1VG2 A;  3V66 A;  5ILH A;  2Z4X A;  2Z7I A;  3N46 F;  4H5C F;  3WC9 A;  3ZCD A;  5AEL A;  2QIS A;  4JVJ F;  1KIZ A;  3KRA B;  2PS6 A;  2E4O A;  5HN8 A;  4LTZ A;  5AFX A;  1N1B A;  3RMG A;  3KRO A;  4LZ0 A;  3ZOU A;  4JZX A;  5IN8 A;  3OAB A;  3TFP A;  5A0K A;  4GAX A;  4KWD A;  2F8C F;  3LK5 A;  2Q80 A;  1FPS A;  1V4E A;  5IK6 A;  3ACX A;  3M01 A;  3LG5 A;  5IKH A;  3CP6 A;  1WL3 A;  1JFA A;  4KFA A;  3TFN A;  3WEF A;  4MC0 A;  5HNA A;  4LFE A;  5EAU A;  3KRC A;  3S4J A;  4JZB A;  1V4H A;  3N5J F;  5DZ2 A;  4NUA A;  3G4F A;  3ZMB A;  2PS4 A;  1VG6 A;  4XQS F;  3SDU A;  5ILK A;  3WJO A;  4JXY A;  3LVS A;  4OKM A;  4LPH F;  5DGM F;  2PS8 A;  2ONH A;  5JV2 F;  3LGZ B;  1V4K A;  3LDW A;  3WCC A;  3LMD A;  5ILD A;  4KVY A;  3B7L A;  3WCA A;  3NF2 A;  3KRP A;  3VJ8 A;  2VF6 A;  3N45 F;  4L2X F;  3LJI A;  3PKO A;  2FTZ A;  4LA5 A;  3PDE A;  5IK9 A;  4P0W A;  2J1P A;  3M00 A;  4PVX F;  3TC1 A;  4H5D F;  3VJ9 A;  3APZ A;  5ILY A;  3WCB A;  1YV5 A;  4KVW A;  4OMH A;  3OAC A;  2I19 A;  3V1X A;  3Q2Z A;  1JFG A;  2ZCO A;  2F89 F;  2J1O A;  5IK0 A;  4E9Z A;  4OMG A;  3ID0 A;  5IMI A;  4GP1 A;  4F6V A;  2F7M F;  4NFI F;  4DHD A;  4K10 A;  3CC9 A;  3IBA A;  3WEG A;  5ILI A;  1HXG A;  3AQC B;  4DWG A;  3EGT A;  4UMJ A;  3WCG A;  4RXA A;  2ZY1 A;  3QKC A;  2E90 A;  4LXW A;  5A0J A;  5E8L A;  2AET A;  4QPF A;  1YQ7 A;  3AE0 A;  4KQ5 A;  4LZ3 A;  5ERM A;  3SDT A;  5HN9 A;  1VG7 A;  2OPN A;  3RYE A;  3BNY A;  5IM1 A;  3ASX A;  5C05 A;  2Z52 A;  2EWG A;  5DW7 A;  3WCM A;  5DHK A;  2DH4 A;  2E92 A;  3BNX A;  4LLS A;  3VJD A;  5B0L A;  3N6K F;  3LGK A;  5CG6 A;  1EZF A;  3ACY A;  3P8R A;  2ZEV A;  3NRI A;  4DI5 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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