5JV0F

Crystal structure of human fpps in complex with an allosteric inhibitor cl-08-038
Total Genus 131
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
131
sequence length
343
structure length
341
Chain Sequence
DVYAQEKQDFVQHFSQIVRVLTEDEMGHPEIGDAIARLKEVLEYNAIGGKYNRGLTVVVAFRELVEPRKQDADSLQRAWTVGWCVELLQAFFLVADDIMDSSLTRRGQICWYQKPGVGLDAINDANLLEACIYRLLKLYCREQPYYLNLIELFLQSSYQTEIGQTLDLLTAPNVDLVRFTEKRYKSIVKYKTAFYSFYLPIAAAMYMAGIDGEKEHANAKKILLEMGEFFQIQDDYLDLFGDPSVTGKIGTDIQDNKCSWLVVQCLQRATPEQYQILKENYGQKEAEKVARVKALYEELDLPAVFLQYEEDSYSHIMALIEQYAAPLPPAVFLGLARKIYK
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Transferase/transferase inhibitor
molecule keywords Farnesyl pyrophosphate synthase
publication title Pharmacophore Mapping of Thienopyrimidine-Based Monophosphonate (ThP-MP) Inhibitors of the Human Farnesyl Pyrophosphate Synthase.
pubmed doi rcsb
source organism Homo sapiens
total genus 131
structure length 341
sequence length 343
ec nomenclature ec 2.5.1.1: Dimethylallyltranstransferase.
pdb deposition date 2016-05-10

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
F PF00348 polyprenyl_synt Polyprenyl synthetase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.600.10 Mainly Alpha Orthogonal Bundle Farnesyl Diphosphate Synthase Farnesyl Diphosphate Synthase 5jv0F00
4NKEA 5IMNA 1YYTA 1WL2A 2AZJA 3WEHA 5DGSF 5ER8A 2PS5A 1YJ4A 4KPDA 1YHMA 3WCIA 1YYRA 3ZOUA 3NF2A 3MAVA 3Q1OA 4PVXF 3ACXA 3Q2ZA 3ZMBA 4LLSA 4K10A 1YYUA 3WEKA 3EZ3A 1YHKA 5IK0A 4LLTA 5EATA 4DXJA 3V1XA 3ICNA 2E91A 2Z4VA 3LLWA 4DHDA 3V1VA 4KVDA 5B0MA 1HX9A 5C05A 4UMJA 3RYWA 3SAEA 1N21A 3OACA 1HM4A 2ZEVA 3ACYA 2PS7A 2EWGA 2Q9YA 5JV1F 2AEKA 5DIQF 3TFNA 5B0LA 3VJEA 5IMPA 2AETA 3CC9A 1YHLA 1YYQA 3IPIA 3N46F 1YYSA 3ICMA 4NFIF 1WL3A 2FORA 4RXCA 1ZW5A 4E9ZA 3TS7A 3WJNA 3ASXA 1KIZA 4RXAA 3WCMA 3VJAA 3S9VA 3LOMA 3ADZA 4E9UA 5IL8A 3TC1A 4KVIA 5ILZA 2Z4XA 3ZL6A 3N5HF 5H9DA 3M00A 2Z50A 3OACB 1RQJA 2F9KF 1RTRA 2ZCQA 3MZVA 5A0JA 1DI1A 4LA5A 2Z4ZA 5E8KA 4KQSA 5ERNA 3WCBA 3P8RA 5AFXA 3WEJA 4ZQ8A 4LTVA 3WJOA 1JFGA 2QISA 5ILDA 2F8ZF 1UBWA 3EFQA 2E8VA 5DGNF 5DW7A 3G4FA 4LFEA 5DZ2A 3LVSA 3SDQA 2Z4WA 3N49F 3IBAA 3LG5A 3WCGA 2E8WA 3LMDA 3SDVA 3CP6A 4EA1A 2F89F 3N6KF 2ONHA 3WSAA 2Z7HA 4H5CF 4Q23A 4LPGF 3DYHA 5IK9A 3M0GA 3NRIA 4LZ3A 4KKMA 5DHIA 5IKHA 4QXSF 4GP1A 3P8LA 3VJ8A 2Z7IA 4MC0A 3QQVA 4LUUA 4OMGA 4MC8A 5B0KA 1DGPA 1N20A 2OGDA 1VG2A 1KIYA 5JV0F 2P1CA 5IMIA 4QPFA 4EA2A 2E94A 3BNYA 5EAUA 3WCLA 5ILKA 3KRFA 4OGUA 1HM7A 3P5RA 4LPHF 5IN8A 3LK5A 3N5JF 4JZBA 4F6VA 1WKZA 4KFAA 1V4EA 4LA6A 2PS6A 2J5CA 1VG6A 3WCEA 3TFPA 5IL3A 5IVGA 2OPNA 5E8LA 2AELA 4F62A 1VG7A 3VJDA 3LSNA 2E4OA 4H5EF 4E1EA 2O1OA 4NFKF 3KRAA 4LFGA 2PS8A 2Q58A 4LIXA 1WL0A 2RAHA 4F6XA 4NG6A 3M02A 1UBVA 3PKOA 3PYAA 4GP2A 4JYXA 3WCDA 2E93A 3ZMCA 1EZFA 1N24A 4N9UA 5ERMA 4WK5A 4KQ5A 3LDWA 1N1BA 4RNQA 3TFVA 3EGTA 3KRCA 2ZY1A 3WCAA 2FTZA 4NUAA 3SDTA 2Z52A 1V4HA 4KPJA 4LOBA 5HN8A 3N1VF 4JZXA 3KRFB 3RYEA 2I19A 4OKZA 4FJQA 1V4KA 3N45F 3S4JA 5E8HA 1VG4A 4P0WA 4P0VA 4MC3A 3NPKA 4RYPA 5ILIA 3LGKA 4LZCA 3LGZB 3LJIA 3ZCDA 2E8TA 3DYGA 3DYFA 3RBMA 3N0FA 4LTZA 3KRAB 3KB9A 5B0JA 5A0IA 4NFJF 5JUZF 3PYBA 3WCHA 4XQTF 3OABA 1N1ZA 1FPSA 4N1ZF 4HD1A 4H5DF 3M01A 4OKMA 3KRCB 5IM1A 5JA0F 1WMWA 1YQ7A 2PS4A 2ZEUA 5I1UA 3Q30A 5DJRF 4DEMF 3SDRA 3QKCA 5B0IA 3ACWA 3WEFA 3WCCA 3RMGA 4KUXA 3WCJA 2F8CF 5AELA 1UBXA 4GA3A 5CG5A 4DZWA 2OA6A 4RXDA 1VG3A 5EASA 4KVWA 5B00A 4NKFA 3NPRA 5DHKA 3N3DA 5ILYA 5HN9A 4DI5A 1V4IA 2J1PA 1HXGA 1UBYA 5HN7A 2AZLA 3P41A 5EROA 3WJKA 2F94F 1RQIA 2ZCSA 3WEGA 1WY0A 3BNXA 1N23A 3OABB 4L2XF 3PH7A 3AQCB 3N0GA 1V4JA 4KK2A 2ZCRA 3LEEA 4RXEA 2ZCOA 4OMHA 2Q9ZA 5DJVF 2H8OA 3KRPA 5IKAA 2AZKA 2E8UA 4KQUA 3WSBA 1WL1A 3WCFA 3PDEA 3ICZA 3N1WF 4LFVF 1YV5A 3AE0A 1N22A 2E95A 4DWBA 2Z78A 4JXNA 3WE9A 3VJ9A 5HNAA 2F7MF 3N3LF 4JVJF 5ILHA 4JXYA 3OYRA 3KROA 5B01A 3B7LA 3V66A 4FP4A 4KVYA 5CG6A 5DGMF 2E8XA 3KBKA 3G4DA 3ID0A 3Q2QA 2E90A 1JFAA 5AYPA 3ICKA 4P0XA 2OPMA 3VJBA 4EA0A 5A0KA 5DJPF 2E92A 5KSXF 4LZ0A 2J1OA 4KWDA 5ILJA 2Z4YA 3M9UA 3P5PA 4DWGA 3KRPB 3WC9A 1HXAA 2ONGA 3UCAA 5IK6A 2DH4A 4XQSF 3AQBB 2F92F 5JV2F 3SDUA 2VF6A 3LZ9A 4PVYF 3W7FA 4LXWA 3APZA 3WEIA 3AQ0A 3CKEA 3KROB 1HXCA 3VJCA 1PS1A 2Q80A 4XQRF 5AHUB 5B03A 5B02A 4GAXA
chains in the Genus database with same CATH superfamily
4NKEA 5IMNA 1YYTA 1WL2A 2AZJA 3WEHA 5DGSF 5ER8A 2PS5A 1YJ4A 4KPDA 1YHMA 3WCIA 1YYRA 3ZOUA 3NF2A 3MAVA 3Q1OA 4PVXF 3ACXA 3Q2ZA 3ZMBA 4LLSA 4K10A 1YYUA 3WEKA 3EZ3A 1YHKA 5IK0A 4LLTA 5EATA 4DXJA 3V1XA 3ICNA 2E91A 2Z4VA 3LLWA 4DHDA 3V1VA 4KVDA 5B0MA 1HX9A 5C05A 4UMJA 3RYWA 3SAEA 1N21A 3OACA 1HM4A 2ZEVA 3ACYA 2PS7A 2EWGA 2Q9YA 5JV1F 2AEKA 5DIQF 3TFNA 5B0LA 3VJEA 5IMPA 2AETA 3CC9A 1YHLA 1YYQA 3IPIA 3N46F 1YYSA 3ICMA 4NFIF 1WL3A 2FORA 4RXCA 1ZW5A 4E9ZA 3TS7A 3WJNA 3ASXA 1KIZA 4RXAA 3WCMA 3VJAA 3S9VA 3LOMA 3ADZA 4E9UA 5IL8A 3TC1A 4KVIA 5ILZA 2Z4XA 3ZL6A 3N5HF 5H9DA 3M00A 2Z50A 3OACB 1RQJA 2F9KF 1RTRA 2ZCQA 3MZVA 5A0JA 1DI1A 4LA5A 2Z4ZA 5E8KA 4KQSA 5ERNA 3WCBA 3P8RA 5AFXA 3WEJA 4ZQ8A 4LTVA 3WJOA 1JFGA 2QISA 5ILDA 2F8ZF 1UBWA 3EFQA 2E8VA 5DGNF 5DW7A 3G4FA 4LFEA 5DZ2A 3LVSA 3SDQA 2Z4WA 3N49F 3IBAA 3LG5A 3WCGA 2E8WA 3LMDA 3SDVA 3CP6A 4EA1A 2F89F 3N6KF 2ONHA 3WSAA 2Z7HA 4H5CF 4Q23A 4LPGF 3DYHA 5IK9A 3M0GA 3NRIA 4LZ3A 4KKMA 5DHIA 5IKHA 4QXSF 4GP1A 3P8LA 3VJ8A 2Z7IA 4MC0A 3QQVA 4LUUA 4OMGA 4MC8A 5B0KA 1DGPA 1N20A 2OGDA 1VG2A 1KIYA 5JV0F 2P1CA 5IMIA 4QPFA 4EA2A 2E94A 3BNYA 5EAUA 3WCLA 5ILKA 3KRFA 4OGUA 1HM7A 3P5RA 4LPHF 5IN8A 3LK5A 3N5JF 4JZBA 4F6VA 1WKZA 4KFAA 1V4EA 4LA6A 2PS6A 2J5CA 1VG6A 3WCEA 3TFPA 5IL3A 5IVGA 2OPNA 5E8LA 2AELA 4F62A 1VG7A 3VJDA 3LSNA 2E4OA 4H5EF 4E1EA 2O1OA 4NFKF 3KRAA 4LFGA 2PS8A 2Q58A 4LIXA 1WL0A 2RAHA 4F6XA 4NG6A 3M02A 1UBVA 3PKOA 3PYAA 4GP2A 4JYXA 3WCDA 2E93A 3ZMCA 1EZFA 1N24A 4N9UA 5ERMA 4WK5A 4KQ5A 3LDWA 1N1BA 4RNQA 3TFVA 3EGTA 3KRCA 2ZY1A 3WCAA 2FTZA 4NUAA 3SDTA 2Z52A 1V4HA 4KPJA 4LOBA 5HN8A 3N1VF 4JZXA 3KRFB 3RYEA 2I19A 4OKZA 4FJQA 1V4KA 3N45F 3S4JA 5E8HA 1VG4A 4P0WA 4P0VA 4MC3A 3NPKA 4RYPA 5ILIA 3LGKA 4LZCA 3LGZB 3LJIA 3ZCDA 2E8TA 3DYGA 3DYFA 3RBMA 3N0FA 4LTZA 3KRAB 3KB9A 5B0JA 5A0IA 4NFJF 5JUZF 3PYBA 3WCHA 4XQTF 3OABA 1N1ZA 1FPSA 4N1ZF 4HD1A 4H5DF 3M01A 4OKMA 3KRCB 5IM1A 5JA0F 1WMWA 1YQ7A 2PS4A 2ZEUA 5I1UA 3Q30A 5DJRF 4DEMF 3SDRA 3QKCA 5B0IA 3ACWA 3WEFA 3WCCA 3RMGA 4KUXA 3WCJA 2F8CF 5AELA 1UBXA 4GA3A 5CG5A 4DZWA 2OA6A 4RXDA 1VG3A 5EASA 4KVWA 5B00A 4NKFA 3NPRA 5DHKA 3N3DA 5ILYA 5HN9A 4DI5A 1V4IA 2J1PA 1HXGA 1UBYA 5HN7A 2AZLA 3P41A 5EROA 3WJKA 2F94F 1RQIA 2ZCSA 3WEGA 1WY0A 3BNXA 1N23A 3OABB 4L2XF 3PH7A 3AQCB 3N0GA 1V4JA 4KK2A 2ZCRA 3LEEA 4RXEA 2ZCOA 4OMHA 2Q9ZA 5DJVF 2H8OA 3KRPA 5IKAA 2AZKA 2E8UA 4KQUA 3WSBA 1WL1A 3WCFA 3PDEA 3ICZA 3N1WF 4LFVF 1YV5A 3AE0A 1N22A 2E95A 4DWBA 2Z78A 4JXNA 3WE9A 3VJ9A 5HNAA 2F7MF 3N3LF 4JVJF 5ILHA 4JXYA 3OYRA 3KROA 5B01A 3B7LA 3V66A 4FP4A 4KVYA 5CG6A 5DGMF 2E8XA 3KBKA 3G4DA 3ID0A 3Q2QA 2E90A 1JFAA 5AYPA 3ICKA 4P0XA 2OPMA 3VJBA 4EA0A 5A0KA 5DJPF 2E92A 5KSXF 4LZ0A 2J1OA 4KWDA 5ILJA 2Z4YA 3M9UA 3P5PA 4DWGA 3KRPB 3WC9A 1HXAA 2ONGA 3UCAA 5IK6A 2DH4A 4XQSF 3AQBB 2F92F 5JV2F 3SDUA 2VF6A 3LZ9A 4PVYF 3W7FA 4LXWA 3APZA 3WEIA 3AQ0A 3CKEA 3KROB 1HXCA 3VJCA 1PS1A 2Q80A 4XQRF 5AHUB 5B03A 5B02A 4GAXA
chains in the Genus database with same CATH topology
4NKEA 5IMNA 1YYTA 1WL2A 2AZJA 3WEHA 5DGSF 5ER8A 2PS5A 1YJ4A 4KPDA 1YHMA 3WCIA 1YYRA 3ZOUA 3NF2A 3MAVA 3Q1OA 4PVXF 3ACXA 3Q2ZA 3ZMBA 4LLSA 4K10A 1YYUA 3WEKA 3EZ3A 1YHKA 5IK0A 4LLTA 5EATA 4DXJA 3V1XA 3ICNA 2E91A 2Z4VA 3LLWA 4DHDA 3V1VA 4KVDA 5B0MA 1HX9A 5C05A 4UMJA 3RYWA 3SAEA 1N21A 3OACA 1HM4A 2ZEVA 3ACYA 2PS7A 2EWGA 2Q9YA 5JV1F 2AEKA 5DIQF 3TFNA 5B0LA 3VJEA 5IMPA 2AETA 3CC9A 1YHLA 1YYQA 3IPIA 3N46F 1YYSA 3ICMA 4NFIF 1WL3A 2FORA 4RXCA 1ZW5A 4E9ZA 3TS7A 3WJNA 3ASXA 1KIZA 4RXAA 3WCMA 3VJAA 3S9VA 3LOMA 3ADZA 4E9UA 5IL8A 3TC1A 4KVIA 5ILZA 2Z4XA 3ZL6A 3N5HF 5H9DA 3M00A 2Z50A 3OACB 1RQJA 2F9KF 1RTRA 2ZCQA 3MZVA 5A0JA 1DI1A 4LA5A 2Z4ZA 5E8KA 4KQSA 5ERNA 3WCBA 3P8RA 5AFXA 3WEJA 4ZQ8A 4LTVA 3WJOA 1JFGA 2QISA 5ILDA 2F8ZF 1UBWA 3EFQA 2E8VA 5DGNF 5DW7A 3G4FA 4LFEA 5DZ2A 3LVSA 3SDQA 2Z4WA 3N49F 3IBAA 3LG5A 3WCGA 2E8WA 3LMDA 3SDVA 3CP6A 4EA1A 2F89F 3N6KF 2ONHA 3WSAA 2Z7HA 4H5CF 4Q23A 4LPGF 3DYHA 5IK9A 3M0GA 3NRIA 4LZ3A 4KKMA 5DHIA 5IKHA 4QXSF 4GP1A 3P8LA 3VJ8A 2Z7IA 4MC0A 3QQVA 4LUUA 4OMGA 4MC8A 5B0KA 1DGPA 1N20A 2OGDA 1VG2A 1KIYA 5JV0F 2P1CA 5IMIA 4QPFA 4EA2A 2E94A 3BNYA 5EAUA 3WCLA 5ILKA 3KRFA 4OGUA 1HM7A 3P5RA 4LPHF 5IN8A 3LK5A 3N5JF 4JZBA 4F6VA 1WKZA 4KFAA 1V4EA 4LA6A 2PS6A 2J5CA 1VG6A 3WCEA 3TFPA 5IL3A 5IVGA 2OPNA 5E8LA 2AELA 4F62A 1VG7A 3VJDA 3LSNA 2E4OA 4H5EF 4E1EA 2O1OA 4NFKF 3KRAA 4LFGA 2PS8A 2Q58A 4LIXA 1WL0A 2RAHA 4F6XA 4NG6A 3M02A 1UBVA 3PKOA 3PYAA 4GP2A 4JYXA 3WCDA 2E93A 3ZMCA 1EZFA 1N24A 4N9UA 5ERMA 4WK5A 4KQ5A 3LDWA 1N1BA 4RNQA 3TFVA 3EGTA 3KRCA 2ZY1A 3WCAA 2FTZA 4NUAA 3SDTA 2Z52A 1V4HA 4KPJA 4LOBA 5HN8A 3N1VF 4JZXA 3KRFB 3RYEA 2I19A 4OKZA 4FJQA 1V4KA 3N45F 3S4JA 5E8HA 1VG4A 4P0WA 4P0VA 4MC3A 3NPKA 4RYPA 5ILIA 3LGKA 4LZCA 3LGZB 3LJIA 3ZCDA 2E8TA 3DYGA 3DYFA 3RBMA 3N0FA 4LTZA 3KRAB 3KB9A 5B0JA 5A0IA 4NFJF 5JUZF 3PYBA 3WCHA 4XQTF 3OABA 1N1ZA 1FPSA 4N1ZF 4HD1A 4H5DF 3M01A 4OKMA 3KRCB 5IM1A 5JA0F 1WMWA 1YQ7A 2PS4A 2ZEUA 5I1UA 3Q30A 5DJRF 4DEMF 3SDRA 3QKCA 5B0IA 3ACWA 3WEFA 3WCCA 3RMGA 4KUXA 3WCJA 2F8CF 5AELA 1UBXA 4GA3A 5CG5A 4DZWA 2OA6A 4RXDA 1VG3A 5EASA 4KVWA 5B00A 4NKFA 3NPRA 5DHKA 3N3DA 5ILYA 5HN9A 4DI5A 1V4IA 2J1PA 1HXGA 1UBYA 5HN7A 2AZLA 3P41A 5EROA 3WJKA 2F94F 1RQIA 2ZCSA 3WEGA 1WY0A 3BNXA 1N23A 3OABB 4L2XF 3PH7A 3AQCB 3N0GA 1V4JA 4KK2A 2ZCRA 3LEEA 4RXEA 2ZCOA 4OMHA 2Q9ZA 5DJVF 2H8OA 3KRPA 5IKAA 2AZKA 2E8UA 4KQUA 3WSBA 1WL1A 3WCFA 3PDEA 3ICZA 3N1WF 4LFVF 1YV5A 3AE0A 1N22A 2E95A 4DWBA 2Z78A 4JXNA 3WE9A 3VJ9A 5HNAA 2F7MF 3N3LF 4JVJF 5ILHA 4JXYA 3OYRA 3KROA 5B01A 3B7LA 3V66A 4FP4A 4KVYA 5CG6A 5DGMF 2E8XA 3KBKA 3G4DA 3ID0A 3Q2QA 2E90A 1JFAA 5AYPA 3ICKA 4P0XA 2OPMA 3VJBA 4EA0A 5A0KA 5DJPF 2E92A 5KSXF 4LZ0A 2J1OA 4KWDA 5ILJA 2Z4YA 3M9UA 3P5PA 4DWGA 3KRPB 3WC9A 1HXAA 2ONGA 3UCAA 5IK6A 2DH4A 4XQSF 3AQBB 2F92F 5JV2F 3SDUA 2VF6A 3LZ9A 4PVYF 3W7FA 4LXWA 3APZA 3WEIA 3AQ0A 3CKEA 3KROB 1HXCA 3VJCA 1PS1A 2Q80A 4XQRF 5AHUB 5B03A 5B02A 4GAXA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4NKE A;  5IMN A;  1YYT A;  1WL2 A;  2AZJ A;  3WEH A;  5DGS F;  5ER8 A;  2PS5 A;  1YJ4 A;  4KPD A;  1YHM A;  3WCI A;  1YYR A;  3ZOU A;  3NF2 A;  3MAV A;  3Q1O A;  4PVX F;  3ACX A;  3Q2Z A;  3ZMB A;  4LLS A;  4K10 A;  1YYU A;  3WEK A;  3EZ3 A;  1YHK A;  5IK0 A;  4LLT A;  5EAT A;  4DXJ A;  3V1X A;  3ICN A;  2E91 A;  2Z4V A;  3LLW A;  4DHD A;  3V1V A;  4KVD A;  5B0M A;  1HX9 A;  5C05 A;  4UMJ A;  3RYW A;  3SAE A;  1N21 A;  3OAC A;  1HM4 A;  2ZEV A;  3ACY A;  2PS7 A;  2EWG A;  2Q9Y A;  5JV1 F;  2AEK A;  5DIQ F;  3TFN A;  5B0L A;  3VJE A;  5IMP A;  2AET A;  3CC9 A;  1YHL A;  1YYQ A;  3IPI A;  3N46 F;  1YYS A;  3ICM A;  4NFI F;  1WL3 A;  2FOR A;  4RXC A;  1ZW5 A;  4E9Z A;  3TS7 A;  3WJN A;  3ASX A;  1KIZ A;  4RXA A;  3WCM A;  3VJA A;  3S9V A;  3LOM A;  3ADZ A;  4E9U A;  5IL8 A;  3TC1 A;  4KVI A;  5ILZ A;  2Z4X A;  3ZL6 A;  3N5H F;  5H9D A;  3M00 A;  2Z50 A;  3OAC B;  1RQJ A;  2F9K F;  1RTR A;  2ZCQ A;  3MZV A;  5A0J A;  1DI1 A;  4LA5 A;  2Z4Z A;  5E8K A;  4KQS A;  5ERN A;  3WCB A;  3P8R A;  5AFX A;  3WEJ A;  4ZQ8 A;  4LTV A;  3WJO A;  1JFG A;  2QIS A;  5ILD A;  2F8Z F;  1UBW A;  3EFQ A;  2E8V A;  5DGN F;  5DW7 A;  3G4F A;  4LFE A;  5DZ2 A;  3LVS A;  3SDQ A;  2Z4W A;  3N49 F;  3IBA A;  3LG5 A;  3WCG A;  2E8W A;  3LMD A;  3SDV A;  3CP6 A;  4EA1 A;  2F89 F;  3N6K F;  2ONH A;  3WSA A;  2Z7H A;  4H5C F;  4Q23 A;  4LPG F;  3DYH A;  5IK9 A;  3M0G A;  3NRI A;  4LZ3 A;  4KKM A;  5DHI A;  5IKH A;  4QXS F;  4GP1 A;  3P8L A;  3VJ8 A;  2Z7I A;  4MC0 A;  3QQV A;  4LUU A;  4OMG A;  4MC8 A;  5B0K A;  1DGP A;  1N20 A;  2OGD A;  1VG2 A;  1KIY A;  5JV0 F;  2P1C A;  5IMI A;  4QPF A;  4EA2 A;  2E94 A;  3BNY A;  5EAU A;  3WCL A;  5ILK A;  3KRF A;  4OGU A;  1HM7 A;  3P5R A;  4LPH F;  5IN8 A;  3LK5 A;  3N5J F;  4JZB A;  4F6V A;  1WKZ A;  4KFA A;  1V4E A;  4LA6 A;  2PS6 A;  2J5C A;  1VG6 A;  3WCE A;  3TFP A;  5IL3 A;  5IVG A;  2OPN A;  5E8L A;  2AEL A;  4F62 A;  1VG7 A;  3VJD A;  3LSN A;  2E4O A;  4H5E F;  4E1E A;  2O1O A;  4NFK F;  3KRA A;  4LFG A;  2PS8 A;  2Q58 A;  4LIX A;  1WL0 A;  2RAH A;  4F6X A;  4NG6 A;  3M02 A;  1UBV A;  3PKO A;  3PYA A;  4GP2 A;  4JYX A;  3WCD A;  2E93 A;  3ZMC A;  1EZF A;  1N24 A;  4N9U A;  5ERM A;  4WK5 A;  4KQ5 A;  3LDW A;  1N1B A;  4RNQ A;  3TFV A;  3EGT A;  3KRC A;  2ZY1 A;  3WCA A;  2FTZ A;  4NUA A;  3SDT A;  2Z52 A;  1V4H A;  4KPJ A;  4LOB A;  5HN8 A;  3N1V F;  4JZX A;  3KRF B;  3RYE A;  2I19 A;  4OKZ A;  4FJQ A;  1V4K A;  3N45 F;  3S4J A;  5E8H A;  1VG4 A;  4P0W A;  4P0V A;  4MC3 A;  3NPK A;  4RYP A;  5ILI A;  3LGK A;  4LZC A;  3LGZ B;  3LJI A;  3ZCD A;  2E8T A;  3DYG A;  3DYF A;  3RBM A;  3N0F A;  4LTZ A;  3KRA B;  3KB9 A;  5B0J A;  5A0I A;  4NFJ F;  5JUZ F;  3PYB A;  3WCH A;  4XQT F;  3OAB A;  1N1Z A;  1FPS A;  4N1Z F;  4HD1 A;  4H5D F;  3M01 A;  4OKM A;  3KRC B;  5IM1 A;  5JA0 F;  1WMW A;  1YQ7 A;  2PS4 A;  2ZEU A;  5I1U A;  3Q30 A;  5DJR F;  4DEM F;  3SDR A;  3QKC A;  5B0I A;  3ACW A;  3WEF A;  3WCC A;  3RMG A;  4KUX A;  3WCJ A;  2F8C F;  5AEL A;  1UBX A;  4GA3 A;  5CG5 A;  4DZW A;  2OA6 A;  4RXD A;  1VG3 A;  5EAS A;  4KVW A;  5B00 A;  4NKF A;  3NPR A;  5DHK A;  3N3D A;  5ILY A;  5HN9 A;  4DI5 A;  1V4I A;  2J1P A;  1HXG A;  1UBY A;  5HN7 A;  2AZL A;  3P41 A;  5ERO A;  3WJK A;  2F94 F;  1RQI A;  2ZCS A;  3WEG A;  1WY0 A;  3BNX A;  1N23 A;  3OAB B;  4L2X F;  3PH7 A;  3AQC B;  3N0G A;  1V4J A;  4KK2 A;  2ZCR A;  3LEE A;  4RXE A;  2ZCO A;  4OMH A;  2Q9Z A;  5DJV F;  2H8O A;  3KRP A;  5IKA A;  2AZK A;  2E8U A;  4KQU A;  3WSB A;  1WL1 A;  3WCF A;  3PDE A;  3ICZ A;  3N1W F;  4LFV F;  1YV5 A;  3AE0 A;  1N22 A;  2E95 A;  4DWB A;  2Z78 A;  4JXN A;  3WE9 A;  3VJ9 A;  5HNA A;  2F7M F;  3N3L F;  4JVJ F;  5ILH A;  4JXY A;  3OYR A;  3KRO A;  5B01 A;  3B7L A;  3V66 A;  4FP4 A;  4KVY A;  5CG6 A;  5DGM F;  2E8X A;  3KBK A;  3G4D A;  3ID0 A;  3Q2Q A;  2E90 A;  1JFA A;  5AYP A;  3ICK A;  4P0X A;  2OPM A;  3VJB A;  4EA0 A;  5A0K A;  5DJP F;  2E92 A;  5KSX F;  4LZ0 A;  2J1O A;  4KWD A;  5ILJ A;  2Z4Y A;  3M9U A;  3P5P A;  4DWG A;  3KRP B;  3WC9 A;  1HXA A;  2ONG A;  3UCA A;  5IK6 A;  2DH4 A;  4XQS F;  3AQB B;  2F92 F;  5JV2 F;  3SDU A;  2VF6 A;  3LZ9 A;  4PVY F;  3W7F A;  4LXW A;  3APZ A;  3WEI A;  3AQ0 A;  3CKE A;  3KRO B;  1HXC A;  3VJC A;  1PS1 A;  2Q80 A;  4XQR F;  5AHU B;  5B03 A;  5B02 A;  4GAX A; 
#chains in the Genus database with same CATH topology
 4NKE A;  5IMN A;  1YYT A;  1WL2 A;  2AZJ A;  3WEH A;  5DGS F;  5ER8 A;  2PS5 A;  1YJ4 A;  4KPD A;  1YHM A;  3WCI A;  1YYR A;  3ZOU A;  3NF2 A;  3MAV A;  3Q1O A;  4PVX F;  3ACX A;  3Q2Z A;  3ZMB A;  4LLS A;  4K10 A;  1YYU A;  3WEK A;  3EZ3 A;  1YHK A;  5IK0 A;  4LLT A;  5EAT A;  4DXJ A;  3V1X A;  3ICN A;  2E91 A;  2Z4V A;  3LLW A;  4DHD A;  3V1V A;  4KVD A;  5B0M A;  1HX9 A;  5C05 A;  4UMJ A;  3RYW A;  3SAE A;  1N21 A;  3OAC A;  1HM4 A;  2ZEV A;  3ACY A;  2PS7 A;  2EWG A;  2Q9Y A;  5JV1 F;  2AEK A;  5DIQ F;  3TFN A;  5B0L A;  3VJE A;  5IMP A;  2AET A;  3CC9 A;  1YHL A;  1YYQ A;  3IPI A;  3N46 F;  1YYS A;  3ICM A;  4NFI F;  1WL3 A;  2FOR A;  4RXC A;  1ZW5 A;  4E9Z A;  3TS7 A;  3WJN A;  3ASX A;  1KIZ A;  4RXA A;  3WCM A;  3VJA A;  3S9V A;  3LOM A;  3ADZ A;  4E9U A;  5IL8 A;  3TC1 A;  4KVI A;  5ILZ A;  2Z4X A;  3ZL6 A;  3N5H F;  5H9D A;  3M00 A;  2Z50 A;  3OAC B;  1RQJ A;  2F9K F;  1RTR A;  2ZCQ A;  3MZV A;  5A0J A;  1DI1 A;  4LA5 A;  2Z4Z A;  5E8K A;  4KQS A;  5ERN A;  3WCB A;  3P8R A;  5AFX A;  3WEJ A;  4ZQ8 A;  4LTV A;  3WJO A;  1JFG A;  2QIS A;  5ILD A;  2F8Z F;  1UBW A;  3EFQ A;  2E8V A;  5DGN F;  5DW7 A;  3G4F A;  4LFE A;  5DZ2 A;  3LVS A;  3SDQ A;  2Z4W A;  3N49 F;  3IBA A;  3LG5 A;  3WCG A;  2E8W A;  3LMD A;  3SDV A;  3CP6 A;  4EA1 A;  2F89 F;  3N6K F;  2ONH A;  3WSA A;  2Z7H A;  4H5C F;  4Q23 A;  4LPG F;  3DYH A;  5IK9 A;  3M0G A;  3NRI A;  4LZ3 A;  4KKM A;  5DHI A;  5IKH A;  4QXS F;  4GP1 A;  3P8L A;  3VJ8 A;  2Z7I A;  4MC0 A;  3QQV A;  4LUU A;  4OMG A;  4MC8 A;  5B0K A;  1DGP A;  1N20 A;  2OGD A;  1VG2 A;  1KIY A;  5JV0 F;  2P1C A;  5IMI A;  4QPF A;  4EA2 A;  2E94 A;  3BNY A;  5EAU A;  3WCL A;  5ILK A;  3KRF A;  4OGU A;  1HM7 A;  3P5R A;  4LPH F;  5IN8 A;  3LK5 A;  3N5J F;  4JZB A;  4F6V A;  1WKZ A;  4KFA A;  1V4E A;  4LA6 A;  2PS6 A;  2J5C A;  1VG6 A;  3WCE A;  3TFP A;  5IL3 A;  5IVG A;  2OPN A;  5E8L A;  2AEL A;  4F62 A;  1VG7 A;  3VJD A;  3LSN A;  2E4O A;  4H5E F;  4E1E A;  2O1O A;  4NFK F;  3KRA A;  4LFG A;  2PS8 A;  2Q58 A;  4LIX A;  1WL0 A;  2RAH A;  4F6X A;  4NG6 A;  3M02 A;  1UBV A;  3PKO A;  3PYA A;  4GP2 A;  4JYX A;  3WCD A;  2E93 A;  3ZMC A;  1EZF A;  1N24 A;  4N9U A;  5ERM A;  4WK5 A;  4KQ5 A;  3LDW A;  1N1B A;  4RNQ A;  3TFV A;  3EGT A;  3KRC A;  2ZY1 A;  3WCA A;  2FTZ A;  4NUA A;  3SDT A;  2Z52 A;  1V4H A;  4KPJ A;  4LOB A;  5HN8 A;  3N1V F;  4JZX A;  3KRF B;  3RYE A;  2I19 A;  4OKZ A;  4FJQ A;  1V4K A;  3N45 F;  3S4J A;  5E8H A;  1VG4 A;  4P0W A;  4P0V A;  4MC3 A;  3NPK A;  4RYP A;  5ILI A;  3LGK A;  4LZC A;  3LGZ B;  3LJI A;  3ZCD A;  2E8T A;  3DYG A;  3DYF A;  3RBM A;  3N0F A;  4LTZ A;  3KRA B;  3KB9 A;  5B0J A;  5A0I A;  4NFJ F;  5JUZ F;  3PYB A;  3WCH A;  4XQT F;  3OAB A;  1N1Z A;  1FPS A;  4N1Z F;  4HD1 A;  4H5D F;  3M01 A;  4OKM A;  3KRC B;  5IM1 A;  5JA0 F;  1WMW A;  1YQ7 A;  2PS4 A;  2ZEU A;  5I1U A;  3Q30 A;  5DJR F;  4DEM F;  3SDR A;  3QKC A;  5B0I A;  3ACW A;  3WEF A;  3WCC A;  3RMG A;  4KUX A;  3WCJ A;  2F8C F;  5AEL A;  1UBX A;  4GA3 A;  5CG5 A;  4DZW A;  2OA6 A;  4RXD A;  1VG3 A;  5EAS A;  4KVW A;  5B00 A;  4NKF A;  3NPR A;  5DHK A;  3N3D A;  5ILY A;  5HN9 A;  4DI5 A;  1V4I A;  2J1P A;  1HXG A;  1UBY A;  5HN7 A;  2AZL A;  3P41 A;  5ERO A;  3WJK A;  2F94 F;  1RQI A;  2ZCS A;  3WEG A;  1WY0 A;  3BNX A;  1N23 A;  3OAB B;  4L2X F;  3PH7 A;  3AQC B;  3N0G A;  1V4J A;  4KK2 A;  2ZCR A;  3LEE A;  4RXE A;  2ZCO A;  4OMH A;  2Q9Z A;  5DJV F;  2H8O A;  3KRP A;  5IKA A;  2AZK A;  2E8U A;  4KQU A;  3WSB A;  1WL1 A;  3WCF A;  3PDE A;  3ICZ A;  3N1W F;  4LFV F;  1YV5 A;  3AE0 A;  1N22 A;  2E95 A;  4DWB A;  2Z78 A;  4JXN A;  3WE9 A;  3VJ9 A;  5HNA A;  2F7M F;  3N3L F;  4JVJ F;  5ILH A;  4JXY A;  3OYR A;  3KRO A;  5B01 A;  3B7L A;  3V66 A;  4FP4 A;  4KVY A;  5CG6 A;  5DGM F;  2E8X A;  3KBK A;  3G4D A;  3ID0 A;  3Q2Q A;  2E90 A;  1JFA A;  5AYP A;  3ICK A;  4P0X A;  2OPM A;  3VJB A;  4EA0 A;  5A0K A;  5DJP F;  2E92 A;  5KSX F;  4LZ0 A;  2J1O A;  4KWD A;  5ILJ A;  2Z4Y A;  3M9U A;  3P5P A;  4DWG A;  3KRP B;  3WC9 A;  1HXA A;  2ONG A;  3UCA A;  5IK6 A;  2DH4 A;  4XQS F;  3AQB B;  2F92 F;  5JV2 F;  3SDU A;  2VF6 A;  3LZ9 A;  4PVY F;  3W7F A;  4LXW A;  3APZ A;  3WEI A;  3AQ0 A;  3CKE A;  3KRO B;  1HXC A;  3VJC A;  1PS1 A;  2Q80 A;  4XQR F;  5AHU B;  5B03 A;  5B02 A;  4GAX A; 
#chains in the Genus database with same CATH homology
 4NKE A;  5IMN A;  1YYT A;  1WL2 A;  2AZJ A;  3WEH A;  5DGS F;  5ER8 A;  2PS5 A;  1YJ4 A;  4KPD A;  1YHM A;  3WCI A;  1YYR A;  3ZOU A;  3NF2 A;  3MAV A;  3Q1O A;  4PVX F;  3ACX A;  3Q2Z A;  3ZMB A;  4LLS A;  4K10 A;  1YYU A;  3WEK A;  3EZ3 A;  1YHK A;  5IK0 A;  4LLT A;  5EAT A;  4DXJ A;  3V1X A;  3ICN A;  2E91 A;  2Z4V A;  3LLW A;  4DHD A;  3V1V A;  4KVD A;  5B0M A;  1HX9 A;  5C05 A;  4UMJ A;  3RYW A;  3SAE A;  1N21 A;  3OAC A;  1HM4 A;  2ZEV A;  3ACY A;  2PS7 A;  2EWG A;  2Q9Y A;  5JV1 F;  2AEK A;  5DIQ F;  3TFN A;  5B0L A;  3VJE A;  5IMP A;  2AET A;  3CC9 A;  1YHL A;  1YYQ A;  3IPI A;  3N46 F;  1YYS A;  3ICM A;  4NFI F;  1WL3 A;  2FOR A;  4RXC A;  1ZW5 A;  4E9Z A;  3TS7 A;  3WJN A;  3ASX A;  1KIZ A;  4RXA A;  3WCM A;  3VJA A;  3S9V A;  3LOM A;  3ADZ A;  4E9U A;  5IL8 A;  3TC1 A;  4KVI A;  5ILZ A;  2Z4X A;  3ZL6 A;  3N5H F;  5H9D A;  3M00 A;  2Z50 A;  3OAC B;  1RQJ A;  2F9K F;  1RTR A;  2ZCQ A;  3MZV A;  5A0J A;  1DI1 A;  4LA5 A;  2Z4Z A;  5E8K A;  4KQS A;  5ERN A;  3WCB A;  3P8R A;  5AFX A;  3WEJ A;  4ZQ8 A;  4LTV A;  3WJO A;  1JFG A;  2QIS A;  5ILD A;  2F8Z F;  1UBW A;  3EFQ A;  2E8V A;  5DGN F;  5DW7 A;  3G4F A;  4LFE A;  5DZ2 A;  3LVS A;  3SDQ A;  2Z4W A;  3N49 F;  3IBA A;  3LG5 A;  3WCG A;  2E8W A;  3LMD A;  3SDV A;  3CP6 A;  4EA1 A;  2F89 F;  3N6K F;  2ONH A;  3WSA A;  2Z7H A;  4H5C F;  4Q23 A;  4LPG F;  3DYH A;  5IK9 A;  3M0G A;  3NRI A;  4LZ3 A;  4KKM A;  5DHI A;  5IKH A;  4QXS F;  4GP1 A;  3P8L A;  3VJ8 A;  2Z7I A;  4MC0 A;  3QQV A;  4LUU A;  4OMG A;  4MC8 A;  5B0K A;  1DGP A;  1N20 A;  2OGD A;  1VG2 A;  1KIY A;  5JV0 F;  2P1C A;  5IMI A;  4QPF A;  4EA2 A;  2E94 A;  3BNY A;  5EAU A;  3WCL A;  5ILK A;  3KRF A;  4OGU A;  1HM7 A;  3P5R A;  4LPH F;  5IN8 A;  3LK5 A;  3N5J F;  4JZB A;  4F6V A;  1WKZ A;  4KFA A;  1V4E A;  4LA6 A;  2PS6 A;  2J5C A;  1VG6 A;  3WCE A;  3TFP A;  5IL3 A;  5IVG A;  2OPN A;  5E8L A;  2AEL A;  4F62 A;  1VG7 A;  3VJD A;  3LSN A;  2E4O A;  4H5E F;  4E1E A;  2O1O A;  4NFK F;  3KRA A;  4LFG A;  2PS8 A;  2Q58 A;  4LIX A;  1WL0 A;  2RAH A;  4F6X A;  4NG6 A;  3M02 A;  1UBV A;  3PKO A;  3PYA A;  4GP2 A;  4JYX A;  3WCD A;  2E93 A;  3ZMC A;  1EZF A;  1N24 A;  4N9U A;  5ERM A;  4WK5 A;  4KQ5 A;  3LDW A;  1N1B A;  4RNQ A;  3TFV A;  3EGT A;  3KRC A;  2ZY1 A;  3WCA A;  2FTZ A;  4NUA A;  3SDT A;  2Z52 A;  1V4H A;  4KPJ A;  4LOB A;  5HN8 A;  3N1V F;  4JZX A;  3KRF B;  3RYE A;  2I19 A;  4OKZ A;  4FJQ A;  1V4K A;  3N45 F;  3S4J A;  5E8H A;  1VG4 A;  4P0W A;  4P0V A;  4MC3 A;  3NPK A;  4RYP A;  5ILI A;  3LGK A;  4LZC A;  3LGZ B;  3LJI A;  3ZCD A;  2E8T A;  3DYG A;  3DYF A;  3RBM A;  3N0F A;  4LTZ A;  3KRA B;  3KB9 A;  5B0J A;  5A0I A;  4NFJ F;  5JUZ F;  3PYB A;  3WCH A;  4XQT F;  3OAB A;  1N1Z A;  1FPS A;  4N1Z F;  4HD1 A;  4H5D F;  3M01 A;  4OKM A;  3KRC B;  5IM1 A;  5JA0 F;  1WMW A;  1YQ7 A;  2PS4 A;  2ZEU A;  5I1U A;  3Q30 A;  5DJR F;  4DEM F;  3SDR A;  3QKC A;  5B0I A;  3ACW A;  3WEF A;  3WCC A;  3RMG A;  4KUX A;  3WCJ A;  2F8C F;  5AEL A;  1UBX A;  4GA3 A;  5CG5 A;  4DZW A;  2OA6 A;  4RXD A;  1VG3 A;  5EAS A;  4KVW A;  5B00 A;  4NKF A;  3NPR A;  5DHK A;  3N3D A;  5ILY A;  5HN9 A;  4DI5 A;  1V4I A;  2J1P A;  1HXG A;  1UBY A;  5HN7 A;  2AZL A;  3P41 A;  5ERO A;  3WJK A;  2F94 F;  1RQI A;  2ZCS A;  3WEG A;  1WY0 A;  3BNX A;  1N23 A;  3OAB B;  4L2X F;  3PH7 A;  3AQC B;  3N0G A;  1V4J A;  4KK2 A;  2ZCR A;  3LEE A;  4RXE A;  2ZCO A;  4OMH A;  2Q9Z A;  5DJV F;  2H8O A;  3KRP A;  5IKA A;  2AZK A;  2E8U A;  4KQU A;  3WSB A;  1WL1 A;  3WCF A;  3PDE A;  3ICZ A;  3N1W F;  4LFV F;  1YV5 A;  3AE0 A;  1N22 A;  2E95 A;  4DWB A;  2Z78 A;  4JXN A;  3WE9 A;  3VJ9 A;  5HNA A;  2F7M F;  3N3L F;  4JVJ F;  5ILH A;  4JXY A;  3OYR A;  3KRO A;  5B01 A;  3B7L A;  3V66 A;  4FP4 A;  4KVY A;  5CG6 A;  5DGM F;  2E8X A;  3KBK A;  3G4D A;  3ID0 A;  3Q2Q A;  2E90 A;  1JFA A;  5AYP A;  3ICK A;  4P0X A;  2OPM A;  3VJB A;  4EA0 A;  5A0K A;  5DJP F;  2E92 A;  5KSX F;  4LZ0 A;  2J1O A;  4KWD A;  5ILJ A;  2Z4Y A;  3M9U A;  3P5P A;  4DWG A;  3KRP B;  3WC9 A;  1HXA A;  2ONG A;  3UCA A;  5IK6 A;  2DH4 A;  4XQS F;  3AQB B;  2F92 F;  5JV2 F;  3SDU A;  2VF6 A;  3LZ9 A;  4PVY F;  3W7F A;  4LXW A;  3APZ A;  3WEI A;  3AQ0 A;  3CKE A;  3KRO B;  1HXC A;  3VJC A;  1PS1 A;  2Q80 A;  4XQR F;  5AHU B;  5B03 A;  5B02 A;  4GAX A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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