5JV1F

Crystal structure of human fpps in complex with an allosteric inhibitor cl-08-066
Total Genus 125
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
125
sequence length
342
structure length
336
Chain Sequence
VYAQEKQDFVQHFSQIVRVLTEHPEIGDAIARLKEVLEYNAIGGKYNRGLTVVVAFRELVEPRKQDADSLQRAWTVGWCVELLQAFFLVADDIMDSSLTRRGQICWYQKPGVGLDAINDANLLEACIYRLLKLYCREQPYYLNLIELFLQSSYQTEIGQTLDLLTAPNVDLVRFTEKRYKSIVKYKTAFYSFYLPIAAAMYMAGIDGEKEHANAKKILLEMGEFFQIQDDYLDLFGDPSVTGKIGTDIQDNKCSWLVVQCLQRATPEQYQILKENYGQKEAEKVARVKALYEELDLPAVFLQYEEDSYSHIMALIEQYAAPLPPAVFLGLARKIYK
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Transferase/transferase inhibitor
molecule keywords Farnesyl pyrophosphate synthase
publication title Pharmacophore Mapping of Thienopyrimidine-Based Monophosphonate (ThP-MP) Inhibitors of the Human Farnesyl Pyrophosphate Synthase.
pubmed doi rcsb
source organism Homo sapiens
total genus 125
structure length 336
sequence length 342
ec nomenclature ec 2.5.1.1: Dimethylallyltranstransferase.
pdb deposition date 2016-05-10

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
F PF00348 polyprenyl_synt Polyprenyl synthetase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.600.10 Mainly Alpha Orthogonal Bundle Farnesyl Diphosphate Synthase Farnesyl Diphosphate Synthase 5jv1F00
3OYRA 4UMJA 4LZCA 4N9UA 2O1OA 4NFIF 2ZCOA 4EA2A 1V4IA 1UBYA 1N21A 3VJAA 3IPIA 3VJBA 2Z4XA 1HXAA 3ADZA 4KVWA 4Q23A 3PH7A 3VJCA 3CC9A 4KKMA 5ILIA 3KRCB 4DEMF 5EAUA 3WEKA 3N3DA 2Z7IA 5HN8A 3WSBA 3ICZA 2Z4YA 1YYSA 2ZY1A 4RXEA 3WE9A 1YHMA 1YYTA 3APZA 1KIZA 3EZ3A 2J1PA 3WCJA 3N1WF 3WCCA 4OKMA 4XQRF 4H5DF 5JUZF 4KQUA 2F92F 1N1ZA 2Z4WA 4OKZA 3NPRA 5JA0F 4JXYA 3KRAB 2F8CF 3AQBB 1DI1A 3PDEA 3ACXA 4HD1A 3WSAA 5HNAA 1N24A 5ILYA 1V4JA 3N0FA 3TFVA 3RMGA 3LG5A 3LGZB 3WCMA 2OGDA 4P0WA 4XQTF 1N20A 1VG3A 4LLSA 2ZEUA 3ZL6A 4KWDA 5IMIA 3AQ0A 1WMWA 3UCAA 3W7FA 2FORA 2ZCQA 3V66A 5AELA 4E9UA 3AE0A 2PS6A 1WL3A 3WEGA 5IMPA 4H5CF 1YQ7A 4LOBA 3S4JA 4NUAA 4F6XA 3KRAA 4KUXA 2F7MF 1UBVA 4LA5A 3MAVA 2EWGA 5B02A 3N46F 1VG6A 4F62A 3RYWA 2Z50A 2AEKA 4LPHF 3P8RA 3VJ8A 3SDVA 5JV0F 5B03A 5ILKA 2E4OA 4KQSA 1UBWA 4LFEA 3G4FA 2F9KF 5DIQF 2RAHA 4LZ3A 3NPKA 4RXDA 3N5HF 5IVGA 3VJEA 1WL1A 4LA6A 4F6VA 3IBAA 3M01A 1YYUA 2PS4A 3WEHA 5JV2F 3LLWA 3P5PA 4LXWA 5ERMA 3PKOA 5IM1A 4DI5A 4RNQA 3VJDA 1YYRA 3PYBA 5DGNF 3PYAA 3Q1OA 3WEJA 4DWBA 4GP1A 2PS8A 3V1VA 3WCEA 1PS1A 5DHIA 1WKZA 1HX9A 3ZOUA 3WCDA 3P41A 3LSNA 3ICKA 4MC8A 4E1EA 5AHUB 3LVSA 2PS5A 1VG2A 5I1UA 1JFGA 4GA3A 3WCIA 3Q2QA 3KB9A 1VG7A 3SDTA 5HN9A 1ZW5A 3M9UA 3TFPA 4FJQA 2ONHA 4JXNA 4LUUA 5IL3A 3ID0A 3WJNA 2AZJA 4JVJF 1WY0A 1JFAA 3LZ9A 3KBKA 1YJ4A 3KROA 2ZCRA 2Q58A 4L2XF 4EA0A 3WEIA 4ZQ8A 1FPSA 4OMGA 3N1VF 5DGMF 3N0GA 3LEEA 5DGSF 5IK0A 5CG5A 5DZ2A 1RTRA 2E8XA 1N1BA 5B0JA 5DW7A 2I19A 4PVYF 3ACWA 3SDRA 3WCFA 1HM7A 2Z4ZA 4LTZA 4E9ZA 4PVXF 2E95A 5IKAA 3EFQA 3NF2A 5EATA 2OA6A 3DYHA 2E8WA 2Q80A 5A0JA 1HM4A 2E8VA 3ZMBA 2E94A 1RQIA 1VG4A 2Q9YA 2Z7HA 3SDQA 1YYQA 1RQJA 5DJVF 2E92A 3KRPB 3WCAA 5B0IA 5HN7A 3DYGA 4KVDA 3DYFA 4NKFA 2ONGA 4P0XA 1HXGA 2F8ZF 3Q30A 5DJPF 4QPFA 3N3LF 5A0KA 4DWGA 3OABA 2E90A 3M0GA 3P5RA 5IMNA 3WCGA 4NG6A 3BNYA 5ILZA 3MZVA 1EZFA 4KPDA 1N22A 3G4DA 3OACA 1YV5A 3SDUA 4LTVA 4JZBA 3N49F 5AFXA 5B0MA 4DZWA 4LIXA 3AQCB 4RYPA 4NKEA 4KPJA 2J5CA 4WK5A 2DH4A 4FP4A 3KROB 4JYXA 3TC1A 3CP6A 3LK5A 5KSXF 3M02A 1V4KA 4KK2A 4LZ0A 3KRPA 3EGTA 5A0IA 4LFVF 5CG6A 4N1ZF 3N45F 5B0KA 2E93A 4NFJF 1N23A 3WCHA 4LLTA 5C05A 5B01A 3N5JF 3ZCDA 4OMHA 4OGUA 5H9DA 3KRFB 5IKHA 2Q9ZA 5IL8A 5ILJA 3LOMA 3WCLA 1HXCA 3WCBA 5IK9A 5AYPA 3ICMA 3LMDA 4MC0A 3QQVA 3P8LA 2E8UA 5E8LA 3WJKA 3RYEA 3BNXA 4P0VA 5EASA 4XQSF 3TS7A 4QXSF 3S9VA 3V1XA 2AZKA 4GAXA 1V4EA 2FTZA 5ILDA 4RXCA 4K10A 3LDWA 3N6KF 3OABB 3ZMCA 3VJ9A 3KRFA 2PS7A 3B7LA 5EROA 2F94F 2E91A 2OPNA 4LPGF 5DJRF 5B00A 3OACB 1YHKA 3KRCA 2ZEVA 4DXJA 2Z4VA 5ILHA 5ER8A 2Z52A 5E8KA 4EA1A 3NRIA 5JV1F 3Q2ZA 1UBXA 5B0LA 2AELA 4JZXA 5IN8A 3ACYA 4MC3A 4NFKF 2Z78A 3WEFA 5DHKA 4H5EF 2F89F 3TFNA 4DHDA 1V4HA 5E8HA 3WC9A 1WL0A 2OPMA 5IK6A 4GP2A 2ZCSA 3CKEA 2J1OA 1DGPA 3M00A 2E8TA 2H8OA 4KVIA 1YHLA 2AZLA 4LFGA 2AETA 3SAEA 4KVYA 4RXAA 5ERNA 3WJOA 3LJIA 2P1CA 4KFAA 4KQ5A 3RBMA 3ASXA 2QISA 1KIYA 2VF6A 3ICNA 3LGKA 3QKCA 1WL2A
chains in the Genus database with same CATH superfamily
3OYRA 4UMJA 4LZCA 4N9UA 2O1OA 4NFIF 2ZCOA 4EA2A 1V4IA 1UBYA 1N21A 3VJAA 3IPIA 3VJBA 2Z4XA 1HXAA 3ADZA 4KVWA 4Q23A 3PH7A 3VJCA 3CC9A 4KKMA 5ILIA 3KRCB 4DEMF 5EAUA 3WEKA 3N3DA 2Z7IA 5HN8A 3WSBA 3ICZA 2Z4YA 1YYSA 2ZY1A 4RXEA 3WE9A 1YHMA 1YYTA 3APZA 1KIZA 3EZ3A 2J1PA 3WCJA 3N1WF 3WCCA 4OKMA 4XQRF 4H5DF 5JUZF 4KQUA 2F92F 1N1ZA 2Z4WA 4OKZA 3NPRA 5JA0F 4JXYA 3KRAB 2F8CF 3AQBB 1DI1A 3PDEA 3ACXA 4HD1A 3WSAA 5HNAA 1N24A 5ILYA 1V4JA 3N0FA 3TFVA 3RMGA 3LG5A 3LGZB 3WCMA 2OGDA 4P0WA 4XQTF 1N20A 1VG3A 4LLSA 2ZEUA 3ZL6A 4KWDA 5IMIA 3AQ0A 1WMWA 3UCAA 3W7FA 2FORA 2ZCQA 3V66A 5AELA 4E9UA 3AE0A 2PS6A 1WL3A 3WEGA 5IMPA 4H5CF 1YQ7A 4LOBA 3S4JA 4NUAA 4F6XA 3KRAA 4KUXA 2F7MF 1UBVA 4LA5A 3MAVA 2EWGA 5B02A 3N46F 1VG6A 4F62A 3RYWA 2Z50A 2AEKA 4LPHF 3P8RA 3VJ8A 3SDVA 5JV0F 5B03A 5ILKA 2E4OA 4KQSA 1UBWA 4LFEA 3G4FA 2F9KF 5DIQF 2RAHA 4LZ3A 3NPKA 4RXDA 3N5HF 5IVGA 3VJEA 1WL1A 4LA6A 4F6VA 3IBAA 3M01A 1YYUA 2PS4A 3WEHA 5JV2F 3LLWA 3P5PA 4LXWA 5ERMA 3PKOA 5IM1A 4DI5A 4RNQA 3VJDA 1YYRA 3PYBA 5DGNF 3PYAA 3Q1OA 3WEJA 4DWBA 4GP1A 2PS8A 3V1VA 3WCEA 1PS1A 5DHIA 1WKZA 1HX9A 3ZOUA 3WCDA 3P41A 3LSNA 3ICKA 4MC8A 4E1EA 5AHUB 3LVSA 2PS5A 1VG2A 5I1UA 1JFGA 4GA3A 3WCIA 3Q2QA 3KB9A 1VG7A 3SDTA 5HN9A 1ZW5A 3M9UA 3TFPA 4FJQA 2ONHA 4JXNA 4LUUA 5IL3A 3ID0A 3WJNA 2AZJA 4JVJF 1WY0A 1JFAA 3LZ9A 3KBKA 1YJ4A 3KROA 2ZCRA 2Q58A 4L2XF 4EA0A 3WEIA 4ZQ8A 1FPSA 4OMGA 3N1VF 5DGMF 3N0GA 3LEEA 5DGSF 5IK0A 5CG5A 5DZ2A 1RTRA 2E8XA 1N1BA 5B0JA 5DW7A 2I19A 4PVYF 3ACWA 3SDRA 3WCFA 1HM7A 2Z4ZA 4LTZA 4E9ZA 4PVXF 2E95A 5IKAA 3EFQA 3NF2A 5EATA 2OA6A 3DYHA 2E8WA 2Q80A 5A0JA 1HM4A 2E8VA 3ZMBA 2E94A 1RQIA 1VG4A 2Q9YA 2Z7HA 3SDQA 1YYQA 1RQJA 5DJVF 2E92A 3KRPB 3WCAA 5B0IA 5HN7A 3DYGA 4KVDA 3DYFA 4NKFA 2ONGA 4P0XA 1HXGA 2F8ZF 3Q30A 5DJPF 4QPFA 3N3LF 5A0KA 4DWGA 3OABA 2E90A 3M0GA 3P5RA 5IMNA 3WCGA 4NG6A 3BNYA 5ILZA 3MZVA 1EZFA 4KPDA 1N22A 3G4DA 3OACA 1YV5A 3SDUA 4LTVA 4JZBA 3N49F 5AFXA 5B0MA 4DZWA 4LIXA 3AQCB 4RYPA 4NKEA 4KPJA 2J5CA 4WK5A 2DH4A 4FP4A 3KROB 4JYXA 3TC1A 3CP6A 3LK5A 5KSXF 3M02A 1V4KA 4KK2A 4LZ0A 3KRPA 3EGTA 5A0IA 4LFVF 5CG6A 4N1ZF 3N45F 5B0KA 2E93A 4NFJF 1N23A 3WCHA 4LLTA 5C05A 5B01A 3N5JF 3ZCDA 4OMHA 4OGUA 5H9DA 3KRFB 5IKHA 2Q9ZA 5IL8A 5ILJA 3LOMA 3WCLA 1HXCA 3WCBA 5IK9A 5AYPA 3ICMA 3LMDA 4MC0A 3QQVA 3P8LA 2E8UA 5E8LA 3WJKA 3RYEA 3BNXA 4P0VA 5EASA 4XQSF 3TS7A 4QXSF 3S9VA 3V1XA 2AZKA 4GAXA 1V4EA 2FTZA 5ILDA 4RXCA 4K10A 3LDWA 3N6KF 3OABB 3ZMCA 3VJ9A 3KRFA 2PS7A 3B7LA 5EROA 2F94F 2E91A 2OPNA 4LPGF 5DJRF 5B00A 3OACB 1YHKA 3KRCA 2ZEVA 4DXJA 2Z4VA 5ILHA 5ER8A 2Z52A 5E8KA 4EA1A 3NRIA 5JV1F 3Q2ZA 1UBXA 5B0LA 2AELA 4JZXA 5IN8A 3ACYA 4MC3A 4NFKF 2Z78A 3WEFA 5DHKA 4H5EF 2F89F 3TFNA 4DHDA 1V4HA 5E8HA 3WC9A 1WL0A 2OPMA 5IK6A 4GP2A 2ZCSA 3CKEA 2J1OA 1DGPA 3M00A 2E8TA 2H8OA 4KVIA 1YHLA 2AZLA 4LFGA 2AETA 3SAEA 4KVYA 4RXAA 5ERNA 3WJOA 3LJIA 2P1CA 4KFAA 4KQ5A 3RBMA 3ASXA 2QISA 1KIYA 2VF6A 3ICNA 3LGKA 3QKCA 1WL2A
chains in the Genus database with same CATH topology
3OYRA 4UMJA 4LZCA 4N9UA 2O1OA 4NFIF 2ZCOA 4EA2A 1V4IA 1UBYA 1N21A 3VJAA 3IPIA 3VJBA 2Z4XA 1HXAA 3ADZA 4KVWA 4Q23A 3PH7A 3VJCA 3CC9A 4KKMA 5ILIA 3KRCB 4DEMF 5EAUA 3WEKA 3N3DA 2Z7IA 5HN8A 3WSBA 3ICZA 2Z4YA 1YYSA 2ZY1A 4RXEA 3WE9A 1YHMA 1YYTA 3APZA 1KIZA 3EZ3A 2J1PA 3WCJA 3N1WF 3WCCA 4OKMA 4XQRF 4H5DF 5JUZF 4KQUA 2F92F 1N1ZA 2Z4WA 4OKZA 3NPRA 5JA0F 4JXYA 3KRAB 2F8CF 3AQBB 1DI1A 3PDEA 3ACXA 4HD1A 3WSAA 5HNAA 1N24A 5ILYA 1V4JA 3N0FA 3TFVA 3RMGA 3LG5A 3LGZB 3WCMA 2OGDA 4P0WA 4XQTF 1N20A 1VG3A 4LLSA 2ZEUA 3ZL6A 4KWDA 5IMIA 3AQ0A 1WMWA 3UCAA 3W7FA 2FORA 2ZCQA 3V66A 5AELA 4E9UA 3AE0A 2PS6A 1WL3A 3WEGA 5IMPA 4H5CF 1YQ7A 4LOBA 3S4JA 4NUAA 4F6XA 3KRAA 4KUXA 2F7MF 1UBVA 4LA5A 3MAVA 2EWGA 5B02A 3N46F 1VG6A 4F62A 3RYWA 2Z50A 2AEKA 4LPHF 3P8RA 3VJ8A 3SDVA 5JV0F 5B03A 5ILKA 2E4OA 4KQSA 1UBWA 4LFEA 3G4FA 2F9KF 5DIQF 2RAHA 4LZ3A 3NPKA 4RXDA 3N5HF 5IVGA 3VJEA 1WL1A 4LA6A 4F6VA 3IBAA 3M01A 1YYUA 2PS4A 3WEHA 5JV2F 3LLWA 3P5PA 4LXWA 5ERMA 3PKOA 5IM1A 4DI5A 4RNQA 3VJDA 1YYRA 3PYBA 5DGNF 3PYAA 3Q1OA 3WEJA 4DWBA 4GP1A 2PS8A 3V1VA 3WCEA 1PS1A 5DHIA 1WKZA 1HX9A 3ZOUA 3WCDA 3P41A 3LSNA 3ICKA 4MC8A 4E1EA 5AHUB 3LVSA 2PS5A 1VG2A 5I1UA 1JFGA 4GA3A 3WCIA 3Q2QA 3KB9A 1VG7A 3SDTA 5HN9A 1ZW5A 3M9UA 3TFPA 4FJQA 2ONHA 4JXNA 4LUUA 5IL3A 3ID0A 3WJNA 2AZJA 4JVJF 1WY0A 1JFAA 3LZ9A 3KBKA 1YJ4A 3KROA 2ZCRA 2Q58A 4L2XF 4EA0A 3WEIA 4ZQ8A 1FPSA 4OMGA 3N1VF 5DGMF 3N0GA 3LEEA 5DGSF 5IK0A 5CG5A 5DZ2A 1RTRA 2E8XA 1N1BA 5B0JA 5DW7A 2I19A 4PVYF 3ACWA 3SDRA 3WCFA 1HM7A 2Z4ZA 4LTZA 4E9ZA 4PVXF 2E95A 5IKAA 3EFQA 3NF2A 5EATA 2OA6A 3DYHA 2E8WA 2Q80A 5A0JA 1HM4A 2E8VA 3ZMBA 2E94A 1RQIA 1VG4A 2Q9YA 2Z7HA 3SDQA 1YYQA 1RQJA 5DJVF 2E92A 3KRPB 3WCAA 5B0IA 5HN7A 3DYGA 4KVDA 3DYFA 4NKFA 2ONGA 4P0XA 1HXGA 2F8ZF 3Q30A 5DJPF 4QPFA 3N3LF 5A0KA 4DWGA 3OABA 2E90A 3M0GA 3P5RA 5IMNA 3WCGA 4NG6A 3BNYA 5ILZA 3MZVA 1EZFA 4KPDA 1N22A 3G4DA 3OACA 1YV5A 3SDUA 4LTVA 4JZBA 3N49F 5AFXA 5B0MA 4DZWA 4LIXA 3AQCB 4RYPA 4NKEA 4KPJA 2J5CA 4WK5A 2DH4A 4FP4A 3KROB 4JYXA 3TC1A 3CP6A 3LK5A 5KSXF 3M02A 1V4KA 4KK2A 4LZ0A 3KRPA 3EGTA 5A0IA 4LFVF 5CG6A 4N1ZF 3N45F 5B0KA 2E93A 4NFJF 1N23A 3WCHA 4LLTA 5C05A 5B01A 3N5JF 3ZCDA 4OMHA 4OGUA 5H9DA 3KRFB 5IKHA 2Q9ZA 5IL8A 5ILJA 3LOMA 3WCLA 1HXCA 3WCBA 5IK9A 5AYPA 3ICMA 3LMDA 4MC0A 3QQVA 3P8LA 2E8UA 5E8LA 3WJKA 3RYEA 3BNXA 4P0VA 5EASA 4XQSF 3TS7A 4QXSF 3S9VA 3V1XA 2AZKA 4GAXA 1V4EA 2FTZA 5ILDA 4RXCA 4K10A 3LDWA 3N6KF 3OABB 3ZMCA 3VJ9A 3KRFA 2PS7A 3B7LA 5EROA 2F94F 2E91A 2OPNA 4LPGF 5DJRF 5B00A 3OACB 1YHKA 3KRCA 2ZEVA 4DXJA 2Z4VA 5ILHA 5ER8A 2Z52A 5E8KA 4EA1A 3NRIA 5JV1F 3Q2ZA 1UBXA 5B0LA 2AELA 4JZXA 5IN8A 3ACYA 4MC3A 4NFKF 2Z78A 3WEFA 5DHKA 4H5EF 2F89F 3TFNA 4DHDA 1V4HA 5E8HA 3WC9A 1WL0A 2OPMA 5IK6A 4GP2A 2ZCSA 3CKEA 2J1OA 1DGPA 3M00A 2E8TA 2H8OA 4KVIA 1YHLA 2AZLA 4LFGA 2AETA 3SAEA 4KVYA 4RXAA 5ERNA 3WJOA 3LJIA 2P1CA 4KFAA 4KQ5A 3RBMA 3ASXA 2QISA 1KIYA 2VF6A 3ICNA 3LGKA 3QKCA 1WL2A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3OYR A;  4UMJ A;  4LZC A;  4N9U A;  2O1O A;  4NFI F;  2ZCO A;  4EA2 A;  1V4I A;  1UBY A;  1N21 A;  3VJA A;  3IPI A;  3VJB A;  2Z4X A;  1HXA A;  3ADZ A;  4KVW A;  4Q23 A;  3PH7 A;  3VJC A;  3CC9 A;  4KKM A;  5ILI A;  3KRC B;  4DEM F;  5EAU A;  3WEK A;  3N3D A;  2Z7I A;  5HN8 A;  3WSB A;  3ICZ A;  2Z4Y A;  1YYS A;  2ZY1 A;  4RXE A;  3WE9 A;  1YHM A;  1YYT A;  3APZ A;  1KIZ A;  3EZ3 A;  2J1P A;  3WCJ A;  3N1W F;  3WCC A;  4OKM A;  4XQR F;  4H5D F;  5JUZ F;  4KQU A;  2F92 F;  1N1Z A;  2Z4W A;  4OKZ A;  3NPR A;  5JA0 F;  4JXY A;  3KRA B;  2F8C F;  3AQB B;  1DI1 A;  3PDE A;  3ACX A;  4HD1 A;  3WSA A;  5HNA A;  1N24 A;  5ILY A;  1V4J A;  3N0F A;  3TFV A;  3RMG A;  3LG5 A;  3LGZ B;  3WCM A;  2OGD A;  4P0W A;  4XQT F;  1N20 A;  1VG3 A;  4LLS A;  2ZEU A;  3ZL6 A;  4KWD A;  5IMI A;  3AQ0 A;  1WMW A;  3UCA A;  3W7F A;  2FOR A;  2ZCQ A;  3V66 A;  5AEL A;  4E9U A;  3AE0 A;  2PS6 A;  1WL3 A;  3WEG A;  5IMP A;  4H5C F;  1YQ7 A;  4LOB A;  3S4J A;  4NUA A;  4F6X A;  3KRA A;  4KUX A;  2F7M F;  1UBV A;  4LA5 A;  3MAV A;  2EWG A;  5B02 A;  3N46 F;  1VG6 A;  4F62 A;  3RYW A;  2Z50 A;  2AEK A;  4LPH F;  3P8R A;  3VJ8 A;  3SDV A;  5JV0 F;  5B03 A;  5ILK A;  2E4O A;  4KQS A;  1UBW A;  4LFE A;  3G4F A;  2F9K F;  5DIQ F;  2RAH A;  4LZ3 A;  3NPK A;  4RXD A;  3N5H F;  5IVG A;  3VJE A;  1WL1 A;  4LA6 A;  4F6V A;  3IBA A;  3M01 A;  1YYU A;  2PS4 A;  3WEH A;  5JV2 F;  3LLW A;  3P5P A;  4LXW A;  5ERM A;  3PKO A;  5IM1 A;  4DI5 A;  4RNQ A;  3VJD A;  1YYR A;  3PYB A;  5DGN F;  3PYA A;  3Q1O A;  3WEJ A;  4DWB A;  4GP1 A;  2PS8 A;  3V1V A;  3WCE A;  1PS1 A;  5DHI A;  1WKZ A;  1HX9 A;  3ZOU A;  3WCD A;  3P41 A;  3LSN A;  3ICK A;  4MC8 A;  4E1E A;  5AHU B;  3LVS A;  2PS5 A;  1VG2 A;  5I1U A;  1JFG A;  4GA3 A;  3WCI A;  3Q2Q A;  3KB9 A;  1VG7 A;  3SDT A;  5HN9 A;  1ZW5 A;  3M9U A;  3TFP A;  4FJQ A;  2ONH A;  4JXN A;  4LUU A;  5IL3 A;  3ID0 A;  3WJN A;  2AZJ A;  4JVJ F;  1WY0 A;  1JFA A;  3LZ9 A;  3KBK A;  1YJ4 A;  3KRO A;  2ZCR A;  2Q58 A;  4L2X F;  4EA0 A;  3WEI A;  4ZQ8 A;  1FPS A;  4OMG A;  3N1V F;  5DGM F;  3N0G A;  3LEE A;  5DGS F;  5IK0 A;  5CG5 A;  5DZ2 A;  1RTR A;  2E8X A;  1N1B A;  5B0J A;  5DW7 A;  2I19 A;  4PVY F;  3ACW A;  3SDR A;  3WCF A;  1HM7 A;  2Z4Z A;  4LTZ A;  4E9Z A;  4PVX F;  2E95 A;  5IKA A;  3EFQ A;  3NF2 A;  5EAT A;  2OA6 A;  3DYH A;  2E8W A;  2Q80 A;  5A0J A;  1HM4 A;  2E8V A;  3ZMB A;  2E94 A;  1RQI A;  1VG4 A;  2Q9Y A;  2Z7H A;  3SDQ A;  1YYQ A;  1RQJ A;  5DJV F;  2E92 A;  3KRP B;  3WCA A;  5B0I A;  5HN7 A;  3DYG A;  4KVD A;  3DYF A;  4NKF A;  2ONG A;  4P0X A;  1HXG A;  2F8Z F;  3Q30 A;  5DJP F;  4QPF A;  3N3L F;  5A0K A;  4DWG A;  3OAB A;  2E90 A;  3M0G A;  3P5R A;  5IMN A;  3WCG A;  4NG6 A;  3BNY A;  5ILZ A;  3MZV A;  1EZF A;  4KPD A;  1N22 A;  3G4D A;  3OAC A;  1YV5 A;  3SDU A;  4LTV A;  4JZB A;  3N49 F;  5AFX A;  5B0M A;  4DZW A;  4LIX A;  3AQC B;  4RYP A;  4NKE A;  4KPJ A;  2J5C A;  4WK5 A;  2DH4 A;  4FP4 A;  3KRO B;  4JYX A;  3TC1 A;  3CP6 A;  3LK5 A;  5KSX F;  3M02 A;  1V4K A;  4KK2 A;  4LZ0 A;  3KRP A;  3EGT A;  5A0I A;  4LFV F;  5CG6 A;  4N1Z F;  3N45 F;  5B0K A;  2E93 A;  4NFJ F;  1N23 A;  3WCH A;  4LLT A;  5C05 A;  5B01 A;  3N5J F;  3ZCD A;  4OMH A;  4OGU A;  5H9D A;  3KRF B;  5IKH A;  2Q9Z A;  5IL8 A;  5ILJ A;  3LOM A;  3WCL A;  1HXC A;  3WCB A;  5IK9 A;  5AYP A;  3ICM A;  3LMD A;  4MC0 A;  3QQV A;  3P8L A;  2E8U A;  5E8L A;  3WJK A;  3RYE A;  3BNX A;  4P0V A;  5EAS A;  4XQS F;  3TS7 A;  4QXS F;  3S9V A;  3V1X A;  2AZK A;  4GAX A;  1V4E A;  2FTZ A;  5ILD A;  4RXC A;  4K10 A;  3LDW A;  3N6K F;  3OAB B;  3ZMC A;  3VJ9 A;  3KRF A;  2PS7 A;  3B7L A;  5ERO A;  2F94 F;  2E91 A;  2OPN A;  4LPG F;  5DJR F;  5B00 A;  3OAC B;  1YHK A;  3KRC A;  2ZEV A;  4DXJ A;  2Z4V A;  5ILH A;  5ER8 A;  2Z52 A;  5E8K A;  4EA1 A;  3NRI A;  5JV1 F;  3Q2Z A;  1UBX A;  5B0L A;  2AEL A;  4JZX A;  5IN8 A;  3ACY A;  4MC3 A;  4NFK F;  2Z78 A;  3WEF A;  5DHK A;  4H5E F;  2F89 F;  3TFN A;  4DHD A;  1V4H A;  5E8H A;  3WC9 A;  1WL0 A;  2OPM A;  5IK6 A;  4GP2 A;  2ZCS A;  3CKE A;  2J1O A;  1DGP A;  3M00 A;  2E8T A;  2H8O A;  4KVI A;  1YHL A;  2AZL A;  4LFG A;  2AET A;  3SAE A;  4KVY A;  4RXA A;  5ERN A;  3WJO A;  3LJI A;  2P1C A;  4KFA A;  4KQ5 A;  3RBM A;  3ASX A;  2QIS A;  1KIY A;  2VF6 A;  3ICN A;  3LGK A;  3QKC A;  1WL2 A; 
#chains in the Genus database with same CATH topology
 3OYR A;  4UMJ A;  4LZC A;  4N9U A;  2O1O A;  4NFI F;  2ZCO A;  4EA2 A;  1V4I A;  1UBY A;  1N21 A;  3VJA A;  3IPI A;  3VJB A;  2Z4X A;  1HXA A;  3ADZ A;  4KVW A;  4Q23 A;  3PH7 A;  3VJC A;  3CC9 A;  4KKM A;  5ILI A;  3KRC B;  4DEM F;  5EAU A;  3WEK A;  3N3D A;  2Z7I A;  5HN8 A;  3WSB A;  3ICZ A;  2Z4Y A;  1YYS A;  2ZY1 A;  4RXE A;  3WE9 A;  1YHM A;  1YYT A;  3APZ A;  1KIZ A;  3EZ3 A;  2J1P A;  3WCJ A;  3N1W F;  3WCC A;  4OKM A;  4XQR F;  4H5D F;  5JUZ F;  4KQU A;  2F92 F;  1N1Z A;  2Z4W A;  4OKZ A;  3NPR A;  5JA0 F;  4JXY A;  3KRA B;  2F8C F;  3AQB B;  1DI1 A;  3PDE A;  3ACX A;  4HD1 A;  3WSA A;  5HNA A;  1N24 A;  5ILY A;  1V4J A;  3N0F A;  3TFV A;  3RMG A;  3LG5 A;  3LGZ B;  3WCM A;  2OGD A;  4P0W A;  4XQT F;  1N20 A;  1VG3 A;  4LLS A;  2ZEU A;  3ZL6 A;  4KWD A;  5IMI A;  3AQ0 A;  1WMW A;  3UCA A;  3W7F A;  2FOR A;  2ZCQ A;  3V66 A;  5AEL A;  4E9U A;  3AE0 A;  2PS6 A;  1WL3 A;  3WEG A;  5IMP A;  4H5C F;  1YQ7 A;  4LOB A;  3S4J A;  4NUA A;  4F6X A;  3KRA A;  4KUX A;  2F7M F;  1UBV A;  4LA5 A;  3MAV A;  2EWG A;  5B02 A;  3N46 F;  1VG6 A;  4F62 A;  3RYW A;  2Z50 A;  2AEK A;  4LPH F;  3P8R A;  3VJ8 A;  3SDV A;  5JV0 F;  5B03 A;  5ILK A;  2E4O A;  4KQS A;  1UBW A;  4LFE A;  3G4F A;  2F9K F;  5DIQ F;  2RAH A;  4LZ3 A;  3NPK A;  4RXD A;  3N5H F;  5IVG A;  3VJE A;  1WL1 A;  4LA6 A;  4F6V A;  3IBA A;  3M01 A;  1YYU A;  2PS4 A;  3WEH A;  5JV2 F;  3LLW A;  3P5P A;  4LXW A;  5ERM A;  3PKO A;  5IM1 A;  4DI5 A;  4RNQ A;  3VJD A;  1YYR A;  3PYB A;  5DGN F;  3PYA A;  3Q1O A;  3WEJ A;  4DWB A;  4GP1 A;  2PS8 A;  3V1V A;  3WCE A;  1PS1 A;  5DHI A;  1WKZ A;  1HX9 A;  3ZOU A;  3WCD A;  3P41 A;  3LSN A;  3ICK A;  4MC8 A;  4E1E A;  5AHU B;  3LVS A;  2PS5 A;  1VG2 A;  5I1U A;  1JFG A;  4GA3 A;  3WCI A;  3Q2Q A;  3KB9 A;  1VG7 A;  3SDT A;  5HN9 A;  1ZW5 A;  3M9U A;  3TFP A;  4FJQ A;  2ONH A;  4JXN A;  4LUU A;  5IL3 A;  3ID0 A;  3WJN A;  2AZJ A;  4JVJ F;  1WY0 A;  1JFA A;  3LZ9 A;  3KBK A;  1YJ4 A;  3KRO A;  2ZCR A;  2Q58 A;  4L2X F;  4EA0 A;  3WEI A;  4ZQ8 A;  1FPS A;  4OMG A;  3N1V F;  5DGM F;  3N0G A;  3LEE A;  5DGS F;  5IK0 A;  5CG5 A;  5DZ2 A;  1RTR A;  2E8X A;  1N1B A;  5B0J A;  5DW7 A;  2I19 A;  4PVY F;  3ACW A;  3SDR A;  3WCF A;  1HM7 A;  2Z4Z A;  4LTZ A;  4E9Z A;  4PVX F;  2E95 A;  5IKA A;  3EFQ A;  3NF2 A;  5EAT A;  2OA6 A;  3DYH A;  2E8W A;  2Q80 A;  5A0J A;  1HM4 A;  2E8V A;  3ZMB A;  2E94 A;  1RQI A;  1VG4 A;  2Q9Y A;  2Z7H A;  3SDQ A;  1YYQ A;  1RQJ A;  5DJV F;  2E92 A;  3KRP B;  3WCA A;  5B0I A;  5HN7 A;  3DYG A;  4KVD A;  3DYF A;  4NKF A;  2ONG A;  4P0X A;  1HXG A;  2F8Z F;  3Q30 A;  5DJP F;  4QPF A;  3N3L F;  5A0K A;  4DWG A;  3OAB A;  2E90 A;  3M0G A;  3P5R A;  5IMN A;  3WCG A;  4NG6 A;  3BNY A;  5ILZ A;  3MZV A;  1EZF A;  4KPD A;  1N22 A;  3G4D A;  3OAC A;  1YV5 A;  3SDU A;  4LTV A;  4JZB A;  3N49 F;  5AFX A;  5B0M A;  4DZW A;  4LIX A;  3AQC B;  4RYP A;  4NKE A;  4KPJ A;  2J5C A;  4WK5 A;  2DH4 A;  4FP4 A;  3KRO B;  4JYX A;  3TC1 A;  3CP6 A;  3LK5 A;  5KSX F;  3M02 A;  1V4K A;  4KK2 A;  4LZ0 A;  3KRP A;  3EGT A;  5A0I A;  4LFV F;  5CG6 A;  4N1Z F;  3N45 F;  5B0K A;  2E93 A;  4NFJ F;  1N23 A;  3WCH A;  4LLT A;  5C05 A;  5B01 A;  3N5J F;  3ZCD A;  4OMH A;  4OGU A;  5H9D A;  3KRF B;  5IKH A;  2Q9Z A;  5IL8 A;  5ILJ A;  3LOM A;  3WCL A;  1HXC A;  3WCB A;  5IK9 A;  5AYP A;  3ICM A;  3LMD A;  4MC0 A;  3QQV A;  3P8L A;  2E8U A;  5E8L A;  3WJK A;  3RYE A;  3BNX A;  4P0V A;  5EAS A;  4XQS F;  3TS7 A;  4QXS F;  3S9V A;  3V1X A;  2AZK A;  4GAX A;  1V4E A;  2FTZ A;  5ILD A;  4RXC A;  4K10 A;  3LDW A;  3N6K F;  3OAB B;  3ZMC A;  3VJ9 A;  3KRF A;  2PS7 A;  3B7L A;  5ERO A;  2F94 F;  2E91 A;  2OPN A;  4LPG F;  5DJR F;  5B00 A;  3OAC B;  1YHK A;  3KRC A;  2ZEV A;  4DXJ A;  2Z4V A;  5ILH A;  5ER8 A;  2Z52 A;  5E8K A;  4EA1 A;  3NRI A;  5JV1 F;  3Q2Z A;  1UBX A;  5B0L A;  2AEL A;  4JZX A;  5IN8 A;  3ACY A;  4MC3 A;  4NFK F;  2Z78 A;  3WEF A;  5DHK A;  4H5E F;  2F89 F;  3TFN A;  4DHD A;  1V4H A;  5E8H A;  3WC9 A;  1WL0 A;  2OPM A;  5IK6 A;  4GP2 A;  2ZCS A;  3CKE A;  2J1O A;  1DGP A;  3M00 A;  2E8T A;  2H8O A;  4KVI A;  1YHL A;  2AZL A;  4LFG A;  2AET A;  3SAE A;  4KVY A;  4RXA A;  5ERN A;  3WJO A;  3LJI A;  2P1C A;  4KFA A;  4KQ5 A;  3RBM A;  3ASX A;  2QIS A;  1KIY A;  2VF6 A;  3ICN A;  3LGK A;  3QKC A;  1WL2 A; 
#chains in the Genus database with same CATH homology
 3OYR A;  4UMJ A;  4LZC A;  4N9U A;  2O1O A;  4NFI F;  2ZCO A;  4EA2 A;  1V4I A;  1UBY A;  1N21 A;  3VJA A;  3IPI A;  3VJB A;  2Z4X A;  1HXA A;  3ADZ A;  4KVW A;  4Q23 A;  3PH7 A;  3VJC A;  3CC9 A;  4KKM A;  5ILI A;  3KRC B;  4DEM F;  5EAU A;  3WEK A;  3N3D A;  2Z7I A;  5HN8 A;  3WSB A;  3ICZ A;  2Z4Y A;  1YYS A;  2ZY1 A;  4RXE A;  3WE9 A;  1YHM A;  1YYT A;  3APZ A;  1KIZ A;  3EZ3 A;  2J1P A;  3WCJ A;  3N1W F;  3WCC A;  4OKM A;  4XQR F;  4H5D F;  5JUZ F;  4KQU A;  2F92 F;  1N1Z A;  2Z4W A;  4OKZ A;  3NPR A;  5JA0 F;  4JXY A;  3KRA B;  2F8C F;  3AQB B;  1DI1 A;  3PDE A;  3ACX A;  4HD1 A;  3WSA A;  5HNA A;  1N24 A;  5ILY A;  1V4J A;  3N0F A;  3TFV A;  3RMG A;  3LG5 A;  3LGZ B;  3WCM A;  2OGD A;  4P0W A;  4XQT F;  1N20 A;  1VG3 A;  4LLS A;  2ZEU A;  3ZL6 A;  4KWD A;  5IMI A;  3AQ0 A;  1WMW A;  3UCA A;  3W7F A;  2FOR A;  2ZCQ A;  3V66 A;  5AEL A;  4E9U A;  3AE0 A;  2PS6 A;  1WL3 A;  3WEG A;  5IMP A;  4H5C F;  1YQ7 A;  4LOB A;  3S4J A;  4NUA A;  4F6X A;  3KRA A;  4KUX A;  2F7M F;  1UBV A;  4LA5 A;  3MAV A;  2EWG A;  5B02 A;  3N46 F;  1VG6 A;  4F62 A;  3RYW A;  2Z50 A;  2AEK A;  4LPH F;  3P8R A;  3VJ8 A;  3SDV A;  5JV0 F;  5B03 A;  5ILK A;  2E4O A;  4KQS A;  1UBW A;  4LFE A;  3G4F A;  2F9K F;  5DIQ F;  2RAH A;  4LZ3 A;  3NPK A;  4RXD A;  3N5H F;  5IVG A;  3VJE A;  1WL1 A;  4LA6 A;  4F6V A;  3IBA A;  3M01 A;  1YYU A;  2PS4 A;  3WEH A;  5JV2 F;  3LLW A;  3P5P A;  4LXW A;  5ERM A;  3PKO A;  5IM1 A;  4DI5 A;  4RNQ A;  3VJD A;  1YYR A;  3PYB A;  5DGN F;  3PYA A;  3Q1O A;  3WEJ A;  4DWB A;  4GP1 A;  2PS8 A;  3V1V A;  3WCE A;  1PS1 A;  5DHI A;  1WKZ A;  1HX9 A;  3ZOU A;  3WCD A;  3P41 A;  3LSN A;  3ICK A;  4MC8 A;  4E1E A;  5AHU B;  3LVS A;  2PS5 A;  1VG2 A;  5I1U A;  1JFG A;  4GA3 A;  3WCI A;  3Q2Q A;  3KB9 A;  1VG7 A;  3SDT A;  5HN9 A;  1ZW5 A;  3M9U A;  3TFP A;  4FJQ A;  2ONH A;  4JXN A;  4LUU A;  5IL3 A;  3ID0 A;  3WJN A;  2AZJ A;  4JVJ F;  1WY0 A;  1JFA A;  3LZ9 A;  3KBK A;  1YJ4 A;  3KRO A;  2ZCR A;  2Q58 A;  4L2X F;  4EA0 A;  3WEI A;  4ZQ8 A;  1FPS A;  4OMG A;  3N1V F;  5DGM F;  3N0G A;  3LEE A;  5DGS F;  5IK0 A;  5CG5 A;  5DZ2 A;  1RTR A;  2E8X A;  1N1B A;  5B0J A;  5DW7 A;  2I19 A;  4PVY F;  3ACW A;  3SDR A;  3WCF A;  1HM7 A;  2Z4Z A;  4LTZ A;  4E9Z A;  4PVX F;  2E95 A;  5IKA A;  3EFQ A;  3NF2 A;  5EAT A;  2OA6 A;  3DYH A;  2E8W A;  2Q80 A;  5A0J A;  1HM4 A;  2E8V A;  3ZMB A;  2E94 A;  1RQI A;  1VG4 A;  2Q9Y A;  2Z7H A;  3SDQ A;  1YYQ A;  1RQJ A;  5DJV F;  2E92 A;  3KRP B;  3WCA A;  5B0I A;  5HN7 A;  3DYG A;  4KVD A;  3DYF A;  4NKF A;  2ONG A;  4P0X A;  1HXG A;  2F8Z F;  3Q30 A;  5DJP F;  4QPF A;  3N3L F;  5A0K A;  4DWG A;  3OAB A;  2E90 A;  3M0G A;  3P5R A;  5IMN A;  3WCG A;  4NG6 A;  3BNY A;  5ILZ A;  3MZV A;  1EZF A;  4KPD A;  1N22 A;  3G4D A;  3OAC A;  1YV5 A;  3SDU A;  4LTV A;  4JZB A;  3N49 F;  5AFX A;  5B0M A;  4DZW A;  4LIX A;  3AQC B;  4RYP A;  4NKE A;  4KPJ A;  2J5C A;  4WK5 A;  2DH4 A;  4FP4 A;  3KRO B;  4JYX A;  3TC1 A;  3CP6 A;  3LK5 A;  5KSX F;  3M02 A;  1V4K A;  4KK2 A;  4LZ0 A;  3KRP A;  3EGT A;  5A0I A;  4LFV F;  5CG6 A;  4N1Z F;  3N45 F;  5B0K A;  2E93 A;  4NFJ F;  1N23 A;  3WCH A;  4LLT A;  5C05 A;  5B01 A;  3N5J F;  3ZCD A;  4OMH A;  4OGU A;  5H9D A;  3KRF B;  5IKH A;  2Q9Z A;  5IL8 A;  5ILJ A;  3LOM A;  3WCL A;  1HXC A;  3WCB A;  5IK9 A;  5AYP A;  3ICM A;  3LMD A;  4MC0 A;  3QQV A;  3P8L A;  2E8U A;  5E8L A;  3WJK A;  3RYE A;  3BNX A;  4P0V A;  5EAS A;  4XQS F;  3TS7 A;  4QXS F;  3S9V A;  3V1X A;  2AZK A;  4GAX A;  1V4E A;  2FTZ A;  5ILD A;  4RXC A;  4K10 A;  3LDW A;  3N6K F;  3OAB B;  3ZMC A;  3VJ9 A;  3KRF A;  2PS7 A;  3B7L A;  5ERO A;  2F94 F;  2E91 A;  2OPN A;  4LPG F;  5DJR F;  5B00 A;  3OAC B;  1YHK A;  3KRC A;  2ZEV A;  4DXJ A;  2Z4V A;  5ILH A;  5ER8 A;  2Z52 A;  5E8K A;  4EA1 A;  3NRI A;  5JV1 F;  3Q2Z A;  1UBX A;  5B0L A;  2AEL A;  4JZX A;  5IN8 A;  3ACY A;  4MC3 A;  4NFK F;  2Z78 A;  3WEF A;  5DHK A;  4H5E F;  2F89 F;  3TFN A;  4DHD A;  1V4H A;  5E8H A;  3WC9 A;  1WL0 A;  2OPM A;  5IK6 A;  4GP2 A;  2ZCS A;  3CKE A;  2J1O A;  1DGP A;  3M00 A;  2E8T A;  2H8O A;  4KVI A;  1YHL A;  2AZL A;  4LFG A;  2AET A;  3SAE A;  4KVY A;  4RXA A;  5ERN A;  3WJO A;  3LJI A;  2P1C A;  4KFA A;  4KQ5 A;  3RBM A;  3ASX A;  2QIS A;  1KIY A;  2VF6 A;  3ICN A;  3LGK A;  3QKC A;  1WL2 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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