5JV2F

Crystal structure of human fpps in complex with an allosteric inhibitor mit-01-055
Total Genus 123
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
123
sequence length
341
structure length
331
Chain Sequence
YAQEKQDFVQHFSQIVRVLTEPEIGDAIARLKEVLEYNAIGGKYNRGLTVVVAFRELVPRKQDADSLQRAWTVGWCVELLQAFFLVADDIMDSSLTRRGQICWYQKPGVGLDAINDANLLEACIYRLLKLYCREQPYYLNLIELFLQSSYQTEIGQTLDLLTAPQGNVDLVRFTEKRYKSIVKYKTAFYSFYLPIAAAMYMAGIDGEKEHANAKKILLEMGEFFQIQDDYLDLFGDPKIGTDIQDNKCSWLVVQCLQRATPEQYQILKENYGQKEAEKVARVKALYEELDLPAVFLQYEEDSYSHIMALIEQYAAPLPPAVFLGLARKIYK
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Transferase/transferase inhibitor
molecule keywords Farnesyl pyrophosphate synthase
publication title Pharmacophore Mapping of Thienopyrimidine-Based Monophosphonate (ThP-MP) Inhibitors of the Human Farnesyl Pyrophosphate Synthase.
pubmed doi rcsb
source organism Homo sapiens
total genus 123
structure length 331
sequence length 341
ec nomenclature ec 2.5.1.1: Dimethylallyltranstransferase.
pdb deposition date 2016-05-10

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
F PF00348 polyprenyl_synt Polyprenyl synthetase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.600.10 Mainly Alpha Orthogonal Bundle Farnesyl Diphosphate Synthase Farnesyl Diphosphate Synthase 5jv2F00
1VG3A 1KIZA 3OABA 2ONHA 3ACWA 2AEKA 4DEMF 1YHLA 4OGUA 3WCMA 1WKZA 3B7LA 1YHMA 5ERNA 2QISA 3TFPA 4WK5A 4KQSA 3ADZA 2E94A 4XQSF 3VJ8A 4QPFA 3SAEA 2ZEUA 3NPKA 2J1OA 1RQJA 2AETA 3PDEA 5HN8A 3VJBA 3KRPA 1HXGA 3ICKA 3WSBA 3WCEA 5E8HA 2Q80A 3RYWA 4NFJF 2Q9ZA 3Q1OA 5A0IA 4KVYA 5HN9A 3V1VA 3S4JA 3N5JF 3WEHA 5EAUA 1VG4A 1HXCA 4LZ3A 3KBKA 4PVYF 3G4DA 3WJKA 5B02A 2E92A 4RYPA 1V4KA 1VG2A 4HD1A 3KROA 2O1OA 2DH4A 4KVWA 1YYQA 2OGDA 4PVXF 1UBVA 5A0KA 2OPMA 2PS5A 5IM1A 5A0JA 3ICZA 3WCGA 4LZCA 3APZA 2E8VA 3LEEA 5DW7A 3TC1A 4DWGA 2ZEVA 3KRCB 4LUUA 4KWDA 3LDWA 3LZ9A 4F6XA 3SDUA 3AE0A 3RYEA 1RQIA 2Z7HA 5E8LA 4GP2A 4LFVF 5IK9A 3ZMBA 1HM7A 4NFIF 3N6KF 3LG5A 4H5DF 4DWBA 5I1UA 5DGMF 1YYUA 5ILKA 3LK5A 3AQ0A 2E4OA 4LXWA 3G4FA 5ILYA 1WL0A 1N1ZA 4EA1A 3V66A 3WEIA 2Q9YA 4DI5A 5HN7A 1N20A 1FPSA 2Z78A 3N0FA 3LVSA 5B0JA 5ILJA 4JYXA 2ZCQA 4RXAA 5IMPA 4P0VA 5AYPA 2E91A 5B01A 2ZCOA 3CC9A 3N3DA 5ILZA 3OABB 4XQTF 5B0IA 2ZY1A 3OACA 4E1EA 4N9UA 4GA3A 5IVGA 3V1XA 4LOBA 2PS6A 5KSXF 5B0KA 3NRIA 3CP6A 3M0GA 2E8TA 3WEJA 1V4IA 1ZW5A 3DYGA 4DHDA 3WCIA 5DZ2A 1WL3A 4KKMA 1DGPA 2Z4VA 1YYSA 3RMGA 2E8WA 5AFXA 2AZJA 3PKOA 2F8CF 4KPJA 3M01A 1VG7A 1HM4A 3ZOUA 3EGTA 3KRPB 5IMNA 2Z4WA 1YQ7A 3BNXA 5EROA 2Z52A 2Z7IA 2ONGA 3PYAA 1KIYA 1DI1A 1V4JA 3ZMCA 4FJQA 3IPIA 3KRAB 1YYRA 4LIXA 1HX9A 2AZLA 4DZWA 3P8LA 3LGKA 3N5HF 4RNQA 5B0MA 3KB9A 3TFNA 2H8OA 3WE9A 5ER8A 2J5CA 5DGNF 2RAHA 5IKAA 3P5PA 4LPGF 3LMDA 3MAVA 3LJIA 4JZBA 2FTZA 4QXSF 5AELA 5ILDA 3SDQA 2Z50A 2P1CA 4OKMA 3ZL6A 2ZCSA 5IMIA 4P0XA 3WEGA 3N0GA 3BNYA 3P8RA 4KUXA 5DHIA 5C05A 4K10A 5ILHA 3WJNA 5DGSF 2F9KF 4FP4A 3Q30A 1N23A 4Q23A 4LLTA 3ID0A 3WCCA 3WEFA 3P41A 3KRFA 4EA0A 1UBXA 5IL8A 4LPHF 3EZ3A 5JA0F 2E8UA 4KPDA 4LFEA 5IK6A 2E90A 4DXJA 1PS1A 2J1PA 2Z4YA 4KVDA 4E9UA 4NG6A 3ZCDA 5IK0A 3RBMA 5DHKA 2PS4A 3WCHA 4OKZA 3NPRA 4JZXA 4NUAA 3W7FA 3AQCB 2Q58A 5H9DA 1N24A 3M02A 4LA5A 1UBYA 4GAXA 4P0WA 3TFVA 3WCAA 3Q2QA 4UMJA 5B0LA 3ASXA 3WCBA 4E9ZA 5ERMA 2PS8A 2VF6A 4MC3A 5DJVF 4JXNA 1HXAA 3SDRA 3WCLA 2FORA 3WCFA 3EFQA 2ZCRA 3SDTA 2EWGA 1YYTA 4KVIA 1YHKA 3IBAA 3N1WF 3TS7A 4KQ5A 3VJAA 1WY0A 2F89F 4NKEA 1WMWA 4JXYA 1RTRA 4NFKF 2F94F 3OACB 3VJCA 3WJOA 4LZ0A 5DJPF 3WCJA 3ICMA 3AQBB 4H5EF 2I19A 4OMGA 3LGZB 4ZQ8A 4LFGA 1WL2A 3UCAA 4RXEA 1JFGA 3N46F 2AELA 2PS7A 5JV2F 1WL1A 3LOMA 2E95A 1VG6A 5B00A 2F7MF 3M9UA 3QQVA 3KRAA 2AZKA 1UBWA 4RXCA 4RXDA 3PH7A 3WSAA 3MZVA 5JV0F 1YV5A 4LLSA 3DYHA 4KQUA 4LTZA 3N3LF 5AHUB 3N49F 3KROB 4GP1A 3WC9A 5HNAA 3N45F 2Z4XA 4KFAA 4LTVA 4KK2A 3WCDA 2F8ZF 5IL3A 3QKCA 2OPNA 3VJ9A 5DJRF 3KRCA 2Z4ZA 3VJDA 4MC0A 4F6VA 3S9VA 4OMHA 3M00A 3WEKA 2F92F 4N1ZF 5E8KA 1N22A 5EATA 1V4HA 5JUZF 3Q2ZA 3KRFB 2OA6A 3ICNA 3NF2A 5IKHA 4H5CF 2E93A 5IN8A 3DYFA 5JV1F 5B03A 4EA2A 4L2XF 1JFAA 3OYRA 2E8XA 3LLWA 3ACXA 1N21A 5CG6A 5DIQF 3SDVA 1V4EA 1EZFA 3CKEA 4MC8A 3PYBA 3VJEA 3N1VF 3P5RA 3ACYA 4JVJF 1N1BA 4LA6A 5ILIA 4NKFA 4F62A 5EASA 4XQRF 5CG5A 1YJ4A 3LSNA
chains in the Genus database with same CATH superfamily
1VG3A 1KIZA 3OABA 2ONHA 3ACWA 2AEKA 4DEMF 1YHLA 4OGUA 3WCMA 1WKZA 3B7LA 1YHMA 5ERNA 2QISA 3TFPA 4WK5A 4KQSA 3ADZA 2E94A 4XQSF 3VJ8A 4QPFA 3SAEA 2ZEUA 3NPKA 2J1OA 1RQJA 2AETA 3PDEA 5HN8A 3VJBA 3KRPA 1HXGA 3ICKA 3WSBA 3WCEA 5E8HA 2Q80A 3RYWA 4NFJF 2Q9ZA 3Q1OA 5A0IA 4KVYA 5HN9A 3V1VA 3S4JA 3N5JF 3WEHA 5EAUA 1VG4A 1HXCA 4LZ3A 3KBKA 4PVYF 3G4DA 3WJKA 5B02A 2E92A 4RYPA 1V4KA 1VG2A 4HD1A 3KROA 2O1OA 2DH4A 4KVWA 1YYQA 2OGDA 4PVXF 1UBVA 5A0KA 2OPMA 2PS5A 5IM1A 5A0JA 3ICZA 3WCGA 4LZCA 3APZA 2E8VA 3LEEA 5DW7A 3TC1A 4DWGA 2ZEVA 3KRCB 4LUUA 4KWDA 3LDWA 3LZ9A 4F6XA 3SDUA 3AE0A 3RYEA 1RQIA 2Z7HA 5E8LA 4GP2A 4LFVF 5IK9A 3ZMBA 1HM7A 4NFIF 3N6KF 3LG5A 4H5DF 4DWBA 5I1UA 5DGMF 1YYUA 5ILKA 3LK5A 3AQ0A 2E4OA 4LXWA 3G4FA 5ILYA 1WL0A 1N1ZA 4EA1A 3V66A 3WEIA 2Q9YA 4DI5A 5HN7A 1N20A 1FPSA 2Z78A 3N0FA 3LVSA 5B0JA 5ILJA 4JYXA 2ZCQA 4RXAA 5IMPA 4P0VA 5AYPA 2E91A 5B01A 2ZCOA 3CC9A 3N3DA 5ILZA 3OABB 4XQTF 5B0IA 2ZY1A 3OACA 4E1EA 4N9UA 4GA3A 5IVGA 3V1XA 4LOBA 2PS6A 5KSXF 5B0KA 3NRIA 3CP6A 3M0GA 2E8TA 3WEJA 1V4IA 1ZW5A 3DYGA 4DHDA 3WCIA 5DZ2A 1WL3A 4KKMA 1DGPA 2Z4VA 1YYSA 3RMGA 2E8WA 5AFXA 2AZJA 3PKOA 2F8CF 4KPJA 3M01A 1VG7A 1HM4A 3ZOUA 3EGTA 3KRPB 5IMNA 2Z4WA 1YQ7A 3BNXA 5EROA 2Z52A 2Z7IA 2ONGA 3PYAA 1KIYA 1DI1A 1V4JA 3ZMCA 4FJQA 3IPIA 3KRAB 1YYRA 4LIXA 1HX9A 2AZLA 4DZWA 3P8LA 3LGKA 3N5HF 4RNQA 5B0MA 3KB9A 3TFNA 2H8OA 3WE9A 5ER8A 2J5CA 5DGNF 2RAHA 5IKAA 3P5PA 4LPGF 3LMDA 3MAVA 3LJIA 4JZBA 2FTZA 4QXSF 5AELA 5ILDA 3SDQA 2Z50A 2P1CA 4OKMA 3ZL6A 2ZCSA 5IMIA 4P0XA 3WEGA 3N0GA 3BNYA 3P8RA 4KUXA 5DHIA 5C05A 4K10A 5ILHA 3WJNA 5DGSF 2F9KF 4FP4A 3Q30A 1N23A 4Q23A 4LLTA 3ID0A 3WCCA 3WEFA 3P41A 3KRFA 4EA0A 1UBXA 5IL8A 4LPHF 3EZ3A 5JA0F 2E8UA 4KPDA 4LFEA 5IK6A 2E90A 4DXJA 1PS1A 2J1PA 2Z4YA 4KVDA 4E9UA 4NG6A 3ZCDA 5IK0A 3RBMA 5DHKA 2PS4A 3WCHA 4OKZA 3NPRA 4JZXA 4NUAA 3W7FA 3AQCB 2Q58A 5H9DA 1N24A 3M02A 4LA5A 1UBYA 4GAXA 4P0WA 3TFVA 3WCAA 3Q2QA 4UMJA 5B0LA 3ASXA 3WCBA 4E9ZA 5ERMA 2PS8A 2VF6A 4MC3A 5DJVF 4JXNA 1HXAA 3SDRA 3WCLA 2FORA 3WCFA 3EFQA 2ZCRA 3SDTA 2EWGA 1YYTA 4KVIA 1YHKA 3IBAA 3N1WF 3TS7A 4KQ5A 3VJAA 1WY0A 2F89F 4NKEA 1WMWA 4JXYA 1RTRA 4NFKF 2F94F 3OACB 3VJCA 3WJOA 4LZ0A 5DJPF 3WCJA 3ICMA 3AQBB 4H5EF 2I19A 4OMGA 3LGZB 4ZQ8A 4LFGA 1WL2A 3UCAA 4RXEA 1JFGA 3N46F 2AELA 2PS7A 5JV2F 1WL1A 3LOMA 2E95A 1VG6A 5B00A 2F7MF 3M9UA 3QQVA 3KRAA 2AZKA 1UBWA 4RXCA 4RXDA 3PH7A 3WSAA 3MZVA 5JV0F 1YV5A 4LLSA 3DYHA 4KQUA 4LTZA 3N3LF 5AHUB 3N49F 3KROB 4GP1A 3WC9A 5HNAA 3N45F 2Z4XA 4KFAA 4LTVA 4KK2A 3WCDA 2F8ZF 5IL3A 3QKCA 2OPNA 3VJ9A 5DJRF 3KRCA 2Z4ZA 3VJDA 4MC0A 4F6VA 3S9VA 4OMHA 3M00A 3WEKA 2F92F 4N1ZF 5E8KA 1N22A 5EATA 1V4HA 5JUZF 3Q2ZA 3KRFB 2OA6A 3ICNA 3NF2A 5IKHA 4H5CF 2E93A 5IN8A 3DYFA 5JV1F 5B03A 4EA2A 4L2XF 1JFAA 3OYRA 2E8XA 3LLWA 3ACXA 1N21A 5CG6A 5DIQF 3SDVA 1V4EA 1EZFA 3CKEA 4MC8A 3PYBA 3VJEA 3N1VF 3P5RA 3ACYA 4JVJF 1N1BA 4LA6A 5ILIA 4NKFA 4F62A 5EASA 4XQRF 5CG5A 1YJ4A 3LSNA
chains in the Genus database with same CATH topology
1VG3A 1KIZA 3OABA 2ONHA 3ACWA 2AEKA 4DEMF 1YHLA 4OGUA 3WCMA 1WKZA 3B7LA 1YHMA 5ERNA 2QISA 3TFPA 4WK5A 4KQSA 3ADZA 2E94A 4XQSF 3VJ8A 4QPFA 3SAEA 2ZEUA 3NPKA 2J1OA 1RQJA 2AETA 3PDEA 5HN8A 3VJBA 3KRPA 1HXGA 3ICKA 3WSBA 3WCEA 5E8HA 2Q80A 3RYWA 4NFJF 2Q9ZA 3Q1OA 5A0IA 4KVYA 5HN9A 3V1VA 3S4JA 3N5JF 3WEHA 5EAUA 1VG4A 1HXCA 4LZ3A 3KBKA 4PVYF 3G4DA 3WJKA 5B02A 2E92A 4RYPA 1V4KA 1VG2A 4HD1A 3KROA 2O1OA 2DH4A 4KVWA 1YYQA 2OGDA 4PVXF 1UBVA 5A0KA 2OPMA 2PS5A 5IM1A 5A0JA 3ICZA 3WCGA 4LZCA 3APZA 2E8VA 3LEEA 5DW7A 3TC1A 4DWGA 2ZEVA 3KRCB 4LUUA 4KWDA 3LDWA 3LZ9A 4F6XA 3SDUA 3AE0A 3RYEA 1RQIA 2Z7HA 5E8LA 4GP2A 4LFVF 5IK9A 3ZMBA 1HM7A 4NFIF 3N6KF 3LG5A 4H5DF 4DWBA 5I1UA 5DGMF 1YYUA 5ILKA 3LK5A 3AQ0A 2E4OA 4LXWA 3G4FA 5ILYA 1WL0A 1N1ZA 4EA1A 3V66A 3WEIA 2Q9YA 4DI5A 5HN7A 1N20A 1FPSA 2Z78A 3N0FA 3LVSA 5B0JA 5ILJA 4JYXA 2ZCQA 4RXAA 5IMPA 4P0VA 5AYPA 2E91A 5B01A 2ZCOA 3CC9A 3N3DA 5ILZA 3OABB 4XQTF 5B0IA 2ZY1A 3OACA 4E1EA 4N9UA 4GA3A 5IVGA 3V1XA 4LOBA 2PS6A 5KSXF 5B0KA 3NRIA 3CP6A 3M0GA 2E8TA 3WEJA 1V4IA 1ZW5A 3DYGA 4DHDA 3WCIA 5DZ2A 1WL3A 4KKMA 1DGPA 2Z4VA 1YYSA 3RMGA 2E8WA 5AFXA 2AZJA 3PKOA 2F8CF 4KPJA 3M01A 1VG7A 1HM4A 3ZOUA 3EGTA 3KRPB 5IMNA 2Z4WA 1YQ7A 3BNXA 5EROA 2Z52A 2Z7IA 2ONGA 3PYAA 1KIYA 1DI1A 1V4JA 3ZMCA 4FJQA 3IPIA 3KRAB 1YYRA 4LIXA 1HX9A 2AZLA 4DZWA 3P8LA 3LGKA 3N5HF 4RNQA 5B0MA 3KB9A 3TFNA 2H8OA 3WE9A 5ER8A 2J5CA 5DGNF 2RAHA 5IKAA 3P5PA 4LPGF 3LMDA 3MAVA 3LJIA 4JZBA 2FTZA 4QXSF 5AELA 5ILDA 3SDQA 2Z50A 2P1CA 4OKMA 3ZL6A 2ZCSA 5IMIA 4P0XA 3WEGA 3N0GA 3BNYA 3P8RA 4KUXA 5DHIA 5C05A 4K10A 5ILHA 3WJNA 5DGSF 2F9KF 4FP4A 3Q30A 1N23A 4Q23A 4LLTA 3ID0A 3WCCA 3WEFA 3P41A 3KRFA 4EA0A 1UBXA 5IL8A 4LPHF 3EZ3A 5JA0F 2E8UA 4KPDA 4LFEA 5IK6A 2E90A 4DXJA 1PS1A 2J1PA 2Z4YA 4KVDA 4E9UA 4NG6A 3ZCDA 5IK0A 3RBMA 5DHKA 2PS4A 3WCHA 4OKZA 3NPRA 4JZXA 4NUAA 3W7FA 3AQCB 2Q58A 5H9DA 1N24A 3M02A 4LA5A 1UBYA 4GAXA 4P0WA 3TFVA 3WCAA 3Q2QA 4UMJA 5B0LA 3ASXA 3WCBA 4E9ZA 5ERMA 2PS8A 2VF6A 4MC3A 5DJVF 4JXNA 1HXAA 3SDRA 3WCLA 2FORA 3WCFA 3EFQA 2ZCRA 3SDTA 2EWGA 1YYTA 4KVIA 1YHKA 3IBAA 3N1WF 3TS7A 4KQ5A 3VJAA 1WY0A 2F89F 4NKEA 1WMWA 4JXYA 1RTRA 4NFKF 2F94F 3OACB 3VJCA 3WJOA 4LZ0A 5DJPF 3WCJA 3ICMA 3AQBB 4H5EF 2I19A 4OMGA 3LGZB 4ZQ8A 4LFGA 1WL2A 3UCAA 4RXEA 1JFGA 3N46F 2AELA 2PS7A 5JV2F 1WL1A 3LOMA 2E95A 1VG6A 5B00A 2F7MF 3M9UA 3QQVA 3KRAA 2AZKA 1UBWA 4RXCA 4RXDA 3PH7A 3WSAA 3MZVA 5JV0F 1YV5A 4LLSA 3DYHA 4KQUA 4LTZA 3N3LF 5AHUB 3N49F 3KROB 4GP1A 3WC9A 5HNAA 3N45F 2Z4XA 4KFAA 4LTVA 4KK2A 3WCDA 2F8ZF 5IL3A 3QKCA 2OPNA 3VJ9A 5DJRF 3KRCA 2Z4ZA 3VJDA 4MC0A 4F6VA 3S9VA 4OMHA 3M00A 3WEKA 2F92F 4N1ZF 5E8KA 1N22A 5EATA 1V4HA 5JUZF 3Q2ZA 3KRFB 2OA6A 3ICNA 3NF2A 5IKHA 4H5CF 2E93A 5IN8A 3DYFA 5JV1F 5B03A 4EA2A 4L2XF 1JFAA 3OYRA 2E8XA 3LLWA 3ACXA 1N21A 5CG6A 5DIQF 3SDVA 1V4EA 1EZFA 3CKEA 4MC8A 3PYBA 3VJEA 3N1VF 3P5RA 3ACYA 4JVJF 1N1BA 4LA6A 5ILIA 4NKFA 4F62A 5EASA 4XQRF 5CG5A 1YJ4A 3LSNA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1VG3 A;  1KIZ A;  3OAB A;  2ONH A;  3ACW A;  2AEK A;  4DEM F;  1YHL A;  4OGU A;  3WCM A;  1WKZ A;  3B7L A;  1YHM A;  5ERN A;  2QIS A;  3TFP A;  4WK5 A;  4KQS A;  3ADZ A;  2E94 A;  4XQS F;  3VJ8 A;  4QPF A;  3SAE A;  2ZEU A;  3NPK A;  2J1O A;  1RQJ A;  2AET A;  3PDE A;  5HN8 A;  3VJB A;  3KRP A;  1HXG A;  3ICK A;  3WSB A;  3WCE A;  5E8H A;  2Q80 A;  3RYW A;  4NFJ F;  2Q9Z A;  3Q1O A;  5A0I A;  4KVY A;  5HN9 A;  3V1V A;  3S4J A;  3N5J F;  3WEH A;  5EAU A;  1VG4 A;  1HXC A;  4LZ3 A;  3KBK A;  4PVY F;  3G4D A;  3WJK A;  5B02 A;  2E92 A;  4RYP A;  1V4K A;  1VG2 A;  4HD1 A;  3KRO A;  2O1O A;  2DH4 A;  4KVW A;  1YYQ A;  2OGD A;  4PVX F;  1UBV A;  5A0K A;  2OPM A;  2PS5 A;  5IM1 A;  5A0J A;  3ICZ A;  3WCG A;  4LZC A;  3APZ A;  2E8V A;  3LEE A;  5DW7 A;  3TC1 A;  4DWG A;  2ZEV A;  3KRC B;  4LUU A;  4KWD A;  3LDW A;  3LZ9 A;  4F6X A;  3SDU A;  3AE0 A;  3RYE A;  1RQI A;  2Z7H A;  5E8L A;  4GP2 A;  4LFV F;  5IK9 A;  3ZMB A;  1HM7 A;  4NFI F;  3N6K F;  3LG5 A;  4H5D F;  4DWB A;  5I1U A;  5DGM F;  1YYU A;  5ILK A;  3LK5 A;  3AQ0 A;  2E4O A;  4LXW A;  3G4F A;  5ILY A;  1WL0 A;  1N1Z A;  4EA1 A;  3V66 A;  3WEI A;  2Q9Y A;  4DI5 A;  5HN7 A;  1N20 A;  1FPS A;  2Z78 A;  3N0F A;  3LVS A;  5B0J A;  5ILJ A;  4JYX A;  2ZCQ A;  4RXA A;  5IMP A;  4P0V A;  5AYP A;  2E91 A;  5B01 A;  2ZCO A;  3CC9 A;  3N3D A;  5ILZ A;  3OAB B;  4XQT F;  5B0I A;  2ZY1 A;  3OAC A;  4E1E A;  4N9U A;  4GA3 A;  5IVG A;  3V1X A;  4LOB A;  2PS6 A;  5KSX F;  5B0K A;  3NRI A;  3CP6 A;  3M0G A;  2E8T A;  3WEJ A;  1V4I A;  1ZW5 A;  3DYG A;  4DHD A;  3WCI A;  5DZ2 A;  1WL3 A;  4KKM A;  1DGP A;  2Z4V A;  1YYS A;  3RMG A;  2E8W A;  5AFX A;  2AZJ A;  3PKO A;  2F8C F;  4KPJ A;  3M01 A;  1VG7 A;  1HM4 A;  3ZOU A;  3EGT A;  3KRP B;  5IMN A;  2Z4W A;  1YQ7 A;  3BNX A;  5ERO A;  2Z52 A;  2Z7I A;  2ONG A;  3PYA A;  1KIY A;  1DI1 A;  1V4J A;  3ZMC A;  4FJQ A;  3IPI A;  3KRA B;  1YYR A;  4LIX A;  1HX9 A;  2AZL A;  4DZW A;  3P8L A;  3LGK A;  3N5H F;  4RNQ A;  5B0M A;  3KB9 A;  3TFN A;  2H8O A;  3WE9 A;  5ER8 A;  2J5C A;  5DGN F;  2RAH A;  5IKA A;  3P5P A;  4LPG F;  3LMD A;  3MAV A;  3LJI A;  4JZB A;  2FTZ A;  4QXS F;  5AEL A;  5ILD A;  3SDQ A;  2Z50 A;  2P1C A;  4OKM A;  3ZL6 A;  2ZCS A;  5IMI A;  4P0X A;  3WEG A;  3N0G A;  3BNY A;  3P8R A;  4KUX A;  5DHI A;  5C05 A;  4K10 A;  5ILH A;  3WJN A;  5DGS F;  2F9K F;  4FP4 A;  3Q30 A;  1N23 A;  4Q23 A;  4LLT A;  3ID0 A;  3WCC A;  3WEF A;  3P41 A;  3KRF A;  4EA0 A;  1UBX A;  5IL8 A;  4LPH F;  3EZ3 A;  5JA0 F;  2E8U A;  4KPD A;  4LFE A;  5IK6 A;  2E90 A;  4DXJ A;  1PS1 A;  2J1P A;  2Z4Y A;  4KVD A;  4E9U A;  4NG6 A;  3ZCD A;  5IK0 A;  3RBM A;  5DHK A;  2PS4 A;  3WCH A;  4OKZ A;  3NPR A;  4JZX A;  4NUA A;  3W7F A;  3AQC B;  2Q58 A;  5H9D A;  1N24 A;  3M02 A;  4LA5 A;  1UBY A;  4GAX A;  4P0W A;  3TFV A;  3WCA A;  3Q2Q A;  4UMJ A;  5B0L A;  3ASX A;  3WCB A;  4E9Z A;  5ERM A;  2PS8 A;  2VF6 A;  4MC3 A;  5DJV F;  4JXN A;  1HXA A;  3SDR A;  3WCL A;  2FOR A;  3WCF A;  3EFQ A;  2ZCR A;  3SDT A;  2EWG A;  1YYT A;  4KVI A;  1YHK A;  3IBA A;  3N1W F;  3TS7 A;  4KQ5 A;  3VJA A;  1WY0 A;  2F89 F;  4NKE A;  1WMW A;  4JXY A;  1RTR A;  4NFK F;  2F94 F;  3OAC B;  3VJC A;  3WJO A;  4LZ0 A;  5DJP F;  3WCJ A;  3ICM A;  3AQB B;  4H5E F;  2I19 A;  4OMG A;  3LGZ B;  4ZQ8 A;  4LFG A;  1WL2 A;  3UCA A;  4RXE A;  1JFG A;  3N46 F;  2AEL A;  2PS7 A;  5JV2 F;  1WL1 A;  3LOM A;  2E95 A;  1VG6 A;  5B00 A;  2F7M F;  3M9U A;  3QQV A;  3KRA A;  2AZK A;  1UBW A;  4RXC A;  4RXD A;  3PH7 A;  3WSA A;  3MZV A;  5JV0 F;  1YV5 A;  4LLS A;  3DYH A;  4KQU A;  4LTZ A;  3N3L F;  5AHU B;  3N49 F;  3KRO B;  4GP1 A;  3WC9 A;  5HNA A;  3N45 F;  2Z4X A;  4KFA A;  4LTV A;  4KK2 A;  3WCD A;  2F8Z F;  5IL3 A;  3QKC A;  2OPN A;  3VJ9 A;  5DJR F;  3KRC A;  2Z4Z A;  3VJD A;  4MC0 A;  4F6V A;  3S9V A;  4OMH A;  3M00 A;  3WEK A;  2F92 F;  4N1Z F;  5E8K A;  1N22 A;  5EAT A;  1V4H A;  5JUZ F;  3Q2Z A;  3KRF B;  2OA6 A;  3ICN A;  3NF2 A;  5IKH A;  4H5C F;  2E93 A;  5IN8 A;  3DYF A;  5JV1 F;  5B03 A;  4EA2 A;  4L2X F;  1JFA A;  3OYR A;  2E8X A;  3LLW A;  3ACX A;  1N21 A;  5CG6 A;  5DIQ F;  3SDV A;  1V4E A;  1EZF A;  3CKE A;  4MC8 A;  3PYB A;  3VJE A;  3N1V F;  3P5R A;  3ACY A;  4JVJ F;  1N1B A;  4LA6 A;  5ILI A;  4NKF A;  4F62 A;  5EAS A;  4XQR F;  5CG5 A;  1YJ4 A;  3LSN A; 
#chains in the Genus database with same CATH topology
 1VG3 A;  1KIZ A;  3OAB A;  2ONH A;  3ACW A;  2AEK A;  4DEM F;  1YHL A;  4OGU A;  3WCM A;  1WKZ A;  3B7L A;  1YHM A;  5ERN A;  2QIS A;  3TFP A;  4WK5 A;  4KQS A;  3ADZ A;  2E94 A;  4XQS F;  3VJ8 A;  4QPF A;  3SAE A;  2ZEU A;  3NPK A;  2J1O A;  1RQJ A;  2AET A;  3PDE A;  5HN8 A;  3VJB A;  3KRP A;  1HXG A;  3ICK A;  3WSB A;  3WCE A;  5E8H A;  2Q80 A;  3RYW A;  4NFJ F;  2Q9Z A;  3Q1O A;  5A0I A;  4KVY A;  5HN9 A;  3V1V A;  3S4J A;  3N5J F;  3WEH A;  5EAU A;  1VG4 A;  1HXC A;  4LZ3 A;  3KBK A;  4PVY F;  3G4D A;  3WJK A;  5B02 A;  2E92 A;  4RYP A;  1V4K A;  1VG2 A;  4HD1 A;  3KRO A;  2O1O A;  2DH4 A;  4KVW A;  1YYQ A;  2OGD A;  4PVX F;  1UBV A;  5A0K A;  2OPM A;  2PS5 A;  5IM1 A;  5A0J A;  3ICZ A;  3WCG A;  4LZC A;  3APZ A;  2E8V A;  3LEE A;  5DW7 A;  3TC1 A;  4DWG A;  2ZEV A;  3KRC B;  4LUU A;  4KWD A;  3LDW A;  3LZ9 A;  4F6X A;  3SDU A;  3AE0 A;  3RYE A;  1RQI A;  2Z7H A;  5E8L A;  4GP2 A;  4LFV F;  5IK9 A;  3ZMB A;  1HM7 A;  4NFI F;  3N6K F;  3LG5 A;  4H5D F;  4DWB A;  5I1U A;  5DGM F;  1YYU A;  5ILK A;  3LK5 A;  3AQ0 A;  2E4O A;  4LXW A;  3G4F A;  5ILY A;  1WL0 A;  1N1Z A;  4EA1 A;  3V66 A;  3WEI A;  2Q9Y A;  4DI5 A;  5HN7 A;  1N20 A;  1FPS A;  2Z78 A;  3N0F A;  3LVS A;  5B0J A;  5ILJ A;  4JYX A;  2ZCQ A;  4RXA A;  5IMP A;  4P0V A;  5AYP A;  2E91 A;  5B01 A;  2ZCO A;  3CC9 A;  3N3D A;  5ILZ A;  3OAB B;  4XQT F;  5B0I A;  2ZY1 A;  3OAC A;  4E1E A;  4N9U A;  4GA3 A;  5IVG A;  3V1X A;  4LOB A;  2PS6 A;  5KSX F;  5B0K A;  3NRI A;  3CP6 A;  3M0G A;  2E8T A;  3WEJ A;  1V4I A;  1ZW5 A;  3DYG A;  4DHD A;  3WCI A;  5DZ2 A;  1WL3 A;  4KKM A;  1DGP A;  2Z4V A;  1YYS A;  3RMG A;  2E8W A;  5AFX A;  2AZJ A;  3PKO A;  2F8C F;  4KPJ A;  3M01 A;  1VG7 A;  1HM4 A;  3ZOU A;  3EGT A;  3KRP B;  5IMN A;  2Z4W A;  1YQ7 A;  3BNX A;  5ERO A;  2Z52 A;  2Z7I A;  2ONG A;  3PYA A;  1KIY A;  1DI1 A;  1V4J A;  3ZMC A;  4FJQ A;  3IPI A;  3KRA B;  1YYR A;  4LIX A;  1HX9 A;  2AZL A;  4DZW A;  3P8L A;  3LGK A;  3N5H F;  4RNQ A;  5B0M A;  3KB9 A;  3TFN A;  2H8O A;  3WE9 A;  5ER8 A;  2J5C A;  5DGN F;  2RAH A;  5IKA A;  3P5P A;  4LPG F;  3LMD A;  3MAV A;  3LJI A;  4JZB A;  2FTZ A;  4QXS F;  5AEL A;  5ILD A;  3SDQ A;  2Z50 A;  2P1C A;  4OKM A;  3ZL6 A;  2ZCS A;  5IMI A;  4P0X A;  3WEG A;  3N0G A;  3BNY A;  3P8R A;  4KUX A;  5DHI A;  5C05 A;  4K10 A;  5ILH A;  3WJN A;  5DGS F;  2F9K F;  4FP4 A;  3Q30 A;  1N23 A;  4Q23 A;  4LLT A;  3ID0 A;  3WCC A;  3WEF A;  3P41 A;  3KRF A;  4EA0 A;  1UBX A;  5IL8 A;  4LPH F;  3EZ3 A;  5JA0 F;  2E8U A;  4KPD A;  4LFE A;  5IK6 A;  2E90 A;  4DXJ A;  1PS1 A;  2J1P A;  2Z4Y A;  4KVD A;  4E9U A;  4NG6 A;  3ZCD A;  5IK0 A;  3RBM A;  5DHK A;  2PS4 A;  3WCH A;  4OKZ A;  3NPR A;  4JZX A;  4NUA A;  3W7F A;  3AQC B;  2Q58 A;  5H9D A;  1N24 A;  3M02 A;  4LA5 A;  1UBY A;  4GAX A;  4P0W A;  3TFV A;  3WCA A;  3Q2Q A;  4UMJ A;  5B0L A;  3ASX A;  3WCB A;  4E9Z A;  5ERM A;  2PS8 A;  2VF6 A;  4MC3 A;  5DJV F;  4JXN A;  1HXA A;  3SDR A;  3WCL A;  2FOR A;  3WCF A;  3EFQ A;  2ZCR A;  3SDT A;  2EWG A;  1YYT A;  4KVI A;  1YHK A;  3IBA A;  3N1W F;  3TS7 A;  4KQ5 A;  3VJA A;  1WY0 A;  2F89 F;  4NKE A;  1WMW A;  4JXY A;  1RTR A;  4NFK F;  2F94 F;  3OAC B;  3VJC A;  3WJO A;  4LZ0 A;  5DJP F;  3WCJ A;  3ICM A;  3AQB B;  4H5E F;  2I19 A;  4OMG A;  3LGZ B;  4ZQ8 A;  4LFG A;  1WL2 A;  3UCA A;  4RXE A;  1JFG A;  3N46 F;  2AEL A;  2PS7 A;  5JV2 F;  1WL1 A;  3LOM A;  2E95 A;  1VG6 A;  5B00 A;  2F7M F;  3M9U A;  3QQV A;  3KRA A;  2AZK A;  1UBW A;  4RXC A;  4RXD A;  3PH7 A;  3WSA A;  3MZV A;  5JV0 F;  1YV5 A;  4LLS A;  3DYH A;  4KQU A;  4LTZ A;  3N3L F;  5AHU B;  3N49 F;  3KRO B;  4GP1 A;  3WC9 A;  5HNA A;  3N45 F;  2Z4X A;  4KFA A;  4LTV A;  4KK2 A;  3WCD A;  2F8Z F;  5IL3 A;  3QKC A;  2OPN A;  3VJ9 A;  5DJR F;  3KRC A;  2Z4Z A;  3VJD A;  4MC0 A;  4F6V A;  3S9V A;  4OMH A;  3M00 A;  3WEK A;  2F92 F;  4N1Z F;  5E8K A;  1N22 A;  5EAT A;  1V4H A;  5JUZ F;  3Q2Z A;  3KRF B;  2OA6 A;  3ICN A;  3NF2 A;  5IKH A;  4H5C F;  2E93 A;  5IN8 A;  3DYF A;  5JV1 F;  5B03 A;  4EA2 A;  4L2X F;  1JFA A;  3OYR A;  2E8X A;  3LLW A;  3ACX A;  1N21 A;  5CG6 A;  5DIQ F;  3SDV A;  1V4E A;  1EZF A;  3CKE A;  4MC8 A;  3PYB A;  3VJE A;  3N1V F;  3P5R A;  3ACY A;  4JVJ F;  1N1B A;  4LA6 A;  5ILI A;  4NKF A;  4F62 A;  5EAS A;  4XQR F;  5CG5 A;  1YJ4 A;  3LSN A; 
#chains in the Genus database with same CATH homology
 1VG3 A;  1KIZ A;  3OAB A;  2ONH A;  3ACW A;  2AEK A;  4DEM F;  1YHL A;  4OGU A;  3WCM A;  1WKZ A;  3B7L A;  1YHM A;  5ERN A;  2QIS A;  3TFP A;  4WK5 A;  4KQS A;  3ADZ A;  2E94 A;  4XQS F;  3VJ8 A;  4QPF A;  3SAE A;  2ZEU A;  3NPK A;  2J1O A;  1RQJ A;  2AET A;  3PDE A;  5HN8 A;  3VJB A;  3KRP A;  1HXG A;  3ICK A;  3WSB A;  3WCE A;  5E8H A;  2Q80 A;  3RYW A;  4NFJ F;  2Q9Z A;  3Q1O A;  5A0I A;  4KVY A;  5HN9 A;  3V1V A;  3S4J A;  3N5J F;  3WEH A;  5EAU A;  1VG4 A;  1HXC A;  4LZ3 A;  3KBK A;  4PVY F;  3G4D A;  3WJK A;  5B02 A;  2E92 A;  4RYP A;  1V4K A;  1VG2 A;  4HD1 A;  3KRO A;  2O1O A;  2DH4 A;  4KVW A;  1YYQ A;  2OGD A;  4PVX F;  1UBV A;  5A0K A;  2OPM A;  2PS5 A;  5IM1 A;  5A0J A;  3ICZ A;  3WCG A;  4LZC A;  3APZ A;  2E8V A;  3LEE A;  5DW7 A;  3TC1 A;  4DWG A;  2ZEV A;  3KRC B;  4LUU A;  4KWD A;  3LDW A;  3LZ9 A;  4F6X A;  3SDU A;  3AE0 A;  3RYE A;  1RQI A;  2Z7H A;  5E8L A;  4GP2 A;  4LFV F;  5IK9 A;  3ZMB A;  1HM7 A;  4NFI F;  3N6K F;  3LG5 A;  4H5D F;  4DWB A;  5I1U A;  5DGM F;  1YYU A;  5ILK A;  3LK5 A;  3AQ0 A;  2E4O A;  4LXW A;  3G4F A;  5ILY A;  1WL0 A;  1N1Z A;  4EA1 A;  3V66 A;  3WEI A;  2Q9Y A;  4DI5 A;  5HN7 A;  1N20 A;  1FPS A;  2Z78 A;  3N0F A;  3LVS A;  5B0J A;  5ILJ A;  4JYX A;  2ZCQ A;  4RXA A;  5IMP A;  4P0V A;  5AYP A;  2E91 A;  5B01 A;  2ZCO A;  3CC9 A;  3N3D A;  5ILZ A;  3OAB B;  4XQT F;  5B0I A;  2ZY1 A;  3OAC A;  4E1E A;  4N9U A;  4GA3 A;  5IVG A;  3V1X A;  4LOB A;  2PS6 A;  5KSX F;  5B0K A;  3NRI A;  3CP6 A;  3M0G A;  2E8T A;  3WEJ A;  1V4I A;  1ZW5 A;  3DYG A;  4DHD A;  3WCI A;  5DZ2 A;  1WL3 A;  4KKM A;  1DGP A;  2Z4V A;  1YYS A;  3RMG A;  2E8W A;  5AFX A;  2AZJ A;  3PKO A;  2F8C F;  4KPJ A;  3M01 A;  1VG7 A;  1HM4 A;  3ZOU A;  3EGT A;  3KRP B;  5IMN A;  2Z4W A;  1YQ7 A;  3BNX A;  5ERO A;  2Z52 A;  2Z7I A;  2ONG A;  3PYA A;  1KIY A;  1DI1 A;  1V4J A;  3ZMC A;  4FJQ A;  3IPI A;  3KRA B;  1YYR A;  4LIX A;  1HX9 A;  2AZL A;  4DZW A;  3P8L A;  3LGK A;  3N5H F;  4RNQ A;  5B0M A;  3KB9 A;  3TFN A;  2H8O A;  3WE9 A;  5ER8 A;  2J5C A;  5DGN F;  2RAH A;  5IKA A;  3P5P A;  4LPG F;  3LMD A;  3MAV A;  3LJI A;  4JZB A;  2FTZ A;  4QXS F;  5AEL A;  5ILD A;  3SDQ A;  2Z50 A;  2P1C A;  4OKM A;  3ZL6 A;  2ZCS A;  5IMI A;  4P0X A;  3WEG A;  3N0G A;  3BNY A;  3P8R A;  4KUX A;  5DHI A;  5C05 A;  4K10 A;  5ILH A;  3WJN A;  5DGS F;  2F9K F;  4FP4 A;  3Q30 A;  1N23 A;  4Q23 A;  4LLT A;  3ID0 A;  3WCC A;  3WEF A;  3P41 A;  3KRF A;  4EA0 A;  1UBX A;  5IL8 A;  4LPH F;  3EZ3 A;  5JA0 F;  2E8U A;  4KPD A;  4LFE A;  5IK6 A;  2E90 A;  4DXJ A;  1PS1 A;  2J1P A;  2Z4Y A;  4KVD A;  4E9U A;  4NG6 A;  3ZCD A;  5IK0 A;  3RBM A;  5DHK A;  2PS4 A;  3WCH A;  4OKZ A;  3NPR A;  4JZX A;  4NUA A;  3W7F A;  3AQC B;  2Q58 A;  5H9D A;  1N24 A;  3M02 A;  4LA5 A;  1UBY A;  4GAX A;  4P0W A;  3TFV A;  3WCA A;  3Q2Q A;  4UMJ A;  5B0L A;  3ASX A;  3WCB A;  4E9Z A;  5ERM A;  2PS8 A;  2VF6 A;  4MC3 A;  5DJV F;  4JXN A;  1HXA A;  3SDR A;  3WCL A;  2FOR A;  3WCF A;  3EFQ A;  2ZCR A;  3SDT A;  2EWG A;  1YYT A;  4KVI A;  1YHK A;  3IBA A;  3N1W F;  3TS7 A;  4KQ5 A;  3VJA A;  1WY0 A;  2F89 F;  4NKE A;  1WMW A;  4JXY A;  1RTR A;  4NFK F;  2F94 F;  3OAC B;  3VJC A;  3WJO A;  4LZ0 A;  5DJP F;  3WCJ A;  3ICM A;  3AQB B;  4H5E F;  2I19 A;  4OMG A;  3LGZ B;  4ZQ8 A;  4LFG A;  1WL2 A;  3UCA A;  4RXE A;  1JFG A;  3N46 F;  2AEL A;  2PS7 A;  5JV2 F;  1WL1 A;  3LOM A;  2E95 A;  1VG6 A;  5B00 A;  2F7M F;  3M9U A;  3QQV A;  3KRA A;  2AZK A;  1UBW A;  4RXC A;  4RXD A;  3PH7 A;  3WSA A;  3MZV A;  5JV0 F;  1YV5 A;  4LLS A;  3DYH A;  4KQU A;  4LTZ A;  3N3L F;  5AHU B;  3N49 F;  3KRO B;  4GP1 A;  3WC9 A;  5HNA A;  3N45 F;  2Z4X A;  4KFA A;  4LTV A;  4KK2 A;  3WCD A;  2F8Z F;  5IL3 A;  3QKC A;  2OPN A;  3VJ9 A;  5DJR F;  3KRC A;  2Z4Z A;  3VJD A;  4MC0 A;  4F6V A;  3S9V A;  4OMH A;  3M00 A;  3WEK A;  2F92 F;  4N1Z F;  5E8K A;  1N22 A;  5EAT A;  1V4H A;  5JUZ F;  3Q2Z A;  3KRF B;  2OA6 A;  3ICN A;  3NF2 A;  5IKH A;  4H5C F;  2E93 A;  5IN8 A;  3DYF A;  5JV1 F;  5B03 A;  4EA2 A;  4L2X F;  1JFA A;  3OYR A;  2E8X A;  3LLW A;  3ACX A;  1N21 A;  5CG6 A;  5DIQ F;  3SDV A;  1V4E A;  1EZF A;  3CKE A;  4MC8 A;  3PYB A;  3VJE A;  3N1V F;  3P5R A;  3ACY A;  4JVJ F;  1N1B A;  4LA6 A;  5ILI A;  4NKF A;  4F62 A;  5EAS A;  4XQR F;  5CG5 A;  1YJ4 A;  3LSN A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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