5KSXF

Crystal structure of human fpps in complex with an allosteric inhibitor am-02-072
Total Genus 132
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
132
sequence length
343
structure length
339
Chain Sequence
VYAQEKQDFVQHFSQIVRVLTEGHPEIGDAIARLKEVLEYNAIGGKYNRGLTVVVAFRELVEPRKQDADSLQRAWTVGWCVELLQAFFLVADDIMDSSLTRRGQICWYQKPGVGLDAINDANLLEACIYRLLKLYCREQPYYLNLIELFLQSSYQTEIGQTLDLLTAPQNVDLVRFTEKRYKSIVKYKTAFYSFYLPIAAAMYMAGIDGEKEHANAKKILLEMGEFFQIQDDYLDLFGDPSVTGKIGTDIQDNKCSWLVVQCLQRATPEQYQILKENYGQKEAEKVARVKALYEELDLPAVFLQYEEDSYSHIMALIEQYAAPLPPAVFLGLARKIYKR
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Pharmacophore Mapping of Thienopyrimidine-Based Monophosphonate (ThP-MP) Inhibitors of the Human Farnesyl Pyrophosphate Synthase.
pubmed doi rcsb
molecule tags Transferase/transferase inhibitor
source organism Homo sapiens
molecule keywords Farnesyl pyrophosphate synthase
total genus 132
structure length 339
sequence length 343
ec nomenclature ec 2.5.1.1: Dimethylallyltranstransferase.
pdb deposition date 2016-07-10

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
F PF00348 polyprenyl_synt Polyprenyl synthetase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.600.10 Mainly Alpha Orthogonal Bundle Farnesyl Diphosphate Synthase Farnesyl Diphosphate Synthase 5ksxF00
4JXNA 5ILYA 5I1UA 2ZEVA 5IVGA 5C05A 1YHKA 4F62A 5B00A 4XQRF 2OPNA 5B03A 3MAVA 3LMDA 3ZMCA 2PS7A 3G4DA 3LSNA 3WCGA 5HNAA 3DYGA 2PS6A 1N21A 1DGPA 3VJ9A 1VG2A 2ZCSA 3CKEA 3KRPA 2F89F 3WCHA 4EA1A 5IMIA 5ILDA 5H9DA 2AZJA 2DH4A 1VG4A 3Q2QA 3N5HF 3QKCA 5ERNA 1HXCA 3S4JA 4KQ5A 3VJBA 1VG3A 1WMWA 4K10A 5E8KA 3ICMA 5KSXF 3KBKA 1N22A 3ZOUA 4KUXA 5AYPA 5JV2F 1RQIA 3ASXA 3P41A 4H5DF 1KIYA 2Q58A 3SAEA 5ILJA 1N1BA 2Z4YA 3ZMBA 1YYQA 3ID0A 3N3DA 1YHMA 4GP2A 1UBWA 3LJIA 4LA5A 2E4OA 3PH7A 2Z52A 3PYAA 1YQ7A 4KFAA 4N1ZF 3LG5A 3G4FA 4LLSA 4FJQA 1UBYA 4RXAA 1VG6A 2E94A 1HXGA 3P5PA 1ZW5A 1V4KA 3MZVA 3ZL6A 3TC1A 3KRPB 3V1VA 4XQSF 5DJRF 1RTRA 3M02A 4NKEA 5AFXA 3OYRA 3N1VF 3WCMA 5IN8A 3S9VA 4JVJF 3WCJA 2OA6A 3ICKA 2AELA 4Q23A 1HX9A 1V4HA 5IL3A 2H8OA 5DW7A 3N1WF 3OACA 5EROA 2J5CA 5IKAA 4DWGA 3N3LF 3WSBA 4OMGA 2RAHA 2ONGA 5AHUB 1YJ4A 1VG7A 4LLTA 4JYXA 3WE9A 2Q9YA 3TFNA 5IK6A 3ICZA 3QQVA 3P8RA 3VJCA 3ACYA 3LEEA 4NFIF 2ZEUA 1N1ZA 4LOBA 5ILHA 3KB9A 4ZQ8A 3EGTA 5B0KA 3WEJA 1YYSA 1N23A 3N0FA 2F9KF 3LOMA 4PVXF 3WEHA 4MC0A 4LUUA 3M00A 2F94F 4GA3A 5JV0F 3CC9A 5EATA 5JUZF 4NG6A 4H5EF 3P5RA 3OACB 2Q9ZA 3ICNA 4F6VA 3WJNA 3OABA 3Q2ZA 4UMJA 2QISA 3WCDA 3Q30A 3LDWA 4RXEA 5B0JA 2AZKA 3ACWA 3KRFA 5A0KA 5EAUA 1V4JA 4DZWA 2AETA 3B7LA 3WCLA 5CG5A 2ZCQA 2AEKA 1PS1A 5DHKA 4OKMA 3TFVA 2ZCRA 5CG6A 5DJPF 2ZCOA 4LIXA 4P0VA 2Z4ZA 3APZA 3P8LA 4XQTF 3PKOA 1EZFA 3NRIA 5A0IA 5A0JA 3V1XA 3N49F 4FP4A 4KWDA 2O1OA 1KIZA 4LZ3A 1UBVA 3ZCDA 4OGUA 4PVYF 4LPGF 3M0GA 3SDVA 3VJ8A 3W7FA 2PS5A 4HD1A 4DEMF 4P0XA 2E8TA 2J1OA 2E90A 2Z7HA 3RMGA 3NF2A 4WK5A 1WL3A 1N20A 2Z4WA 5DGMF 4L2XF 4F6XA 5ERMA 3OABB 2EWGA 1FPSA 5B0MA 3PYBA 4RNQA 5B01A 2OPMA 3KRFB 1YYTA 4DWBA 2E8XA 1YYUA 3LGKA 4DHDA 3IPIA 5EASA 4RXDA 3LZ9A 3IBAA 3VJEA 5IKHA 5IM1A 1WL0A 4KVIA 1JFAA 3EFQA 4KPJA 5DGSF 3RYWA 1HXAA 5IK0A 4LPHF 3N5JF 2I19A 3DYFA 4LXWA 1V4IA 5IMPA 3SDTA 2F8CF 5HN7A 4KQSA 2Z4VA 3PDEA 2Z50A 3N6KF 4DXJA 3WC9A 3SDRA 5HN8A 1WL2A 5DGNF 2FTZA 2AZLA 4LFEA 1YYRA 3SDQA 3WJKA 5ILKA 3AE0A 1YHLA 4MC8A 3VJDA 3WCEA 4KKMA 2F8ZF 1WKZA 1RQJA 1JFGA 2E93A 2Q80A 4JXYA 4GAXA 3WEFA 4GP1A 1HM7A 4KQUA 2E8VA 3KROA 5DIQF 3KRAA 3N0GA 3WCCA 4JZBA 3V66A 5IMNA 2F7MF 2ONHA 3ADZA 3RYEA 5AELA 4LZ0A 3AQCB 3WCAA 5IK9A 3M01A 5B0LA 3WSAA 3WCIA 5DJVF 3KRCA 4KVWA 1YV5A 4N9UA 3ACXA 5ILIA 3WJOA 4OKZA 4NUAA 4LTZA 3LLWA 2ZY1A 2FORA 3AQBB 4LTVA 4KVYA 4DI5A 4KVDA 2PS4A 4QPFA 4QXSF 5ER8A 3BNXA 2P1CA 4RYPA 2Z4XA 4KK2A 5E8LA 2Z78A 3BNYA 2E91A 3WEKA 2VF6A 2E8UA 3EZ3A 5IL8A 1UBXA 1DI1A 4NFKF 4NFJF 4JZXA 5B0IA 4E9UA 3WCBA 1WL1A 4MC3A 4EA2A 3NPRA 1WY0A 4EA0A 2OGDA 3KROB 3SDUA 3KRAB 3DYHA 3RBMA 5DZ2A 1HM4A 3WEGA 3TS7A 2E92A 5DHIA 2E95A 3M9UA 4H5CF 3VJAA 5B02A 3LGZB 3AQ0A 4KPDA 3LVSA 5HN9A 3WCFA 3KRCB 1N24A 2E8WA 4E9ZA 2F92F 3N45F 3LK5A 4OMHA 2PS8A 4LA6A 3WEIA 4NKFA 4LZCA 2Z7IA 5JV1F 3N46F 4LFVF 3NPKA 2J1PA 3Q1OA 4RXCA 5JA0F 3TFPA 5ILZA 1V4EA 4LFGA 3CP6A 4E1EA 4P0WA 3UCAA 5E8HA
chains in the Genus database with same CATH superfamily
4JXNA 5ILYA 5I1UA 2ZEVA 5IVGA 5C05A 1YHKA 4F62A 5B00A 4XQRF 2OPNA 5B03A 3MAVA 3LMDA 3ZMCA 2PS7A 3G4DA 3LSNA 3WCGA 5HNAA 3DYGA 2PS6A 1N21A 1DGPA 3VJ9A 1VG2A 2ZCSA 3CKEA 3KRPA 2F89F 3WCHA 4EA1A 5IMIA 5ILDA 5H9DA 2AZJA 2DH4A 1VG4A 3Q2QA 3N5HF 3QKCA 5ERNA 1HXCA 3S4JA 4KQ5A 3VJBA 1VG3A 1WMWA 4K10A 5E8KA 3ICMA 5KSXF 3KBKA 1N22A 3ZOUA 4KUXA 5AYPA 5JV2F 1RQIA 3ASXA 3P41A 4H5DF 1KIYA 2Q58A 3SAEA 5ILJA 1N1BA 2Z4YA 3ZMBA 1YYQA 3ID0A 3N3DA 1YHMA 4GP2A 1UBWA 3LJIA 4LA5A 2E4OA 3PH7A 2Z52A 3PYAA 1YQ7A 4KFAA 4N1ZF 3LG5A 3G4FA 4LLSA 4FJQA 1UBYA 4RXAA 1VG6A 2E94A 1HXGA 3P5PA 1ZW5A 1V4KA 3MZVA 3ZL6A 3TC1A 3KRPB 3V1VA 4XQSF 5DJRF 1RTRA 3M02A 4NKEA 5AFXA 3OYRA 3N1VF 3WCMA 5IN8A 3S9VA 4JVJF 3WCJA 2OA6A 3ICKA 2AELA 4Q23A 1HX9A 1V4HA 5IL3A 2H8OA 5DW7A 3N1WF 3OACA 5EROA 2J5CA 5IKAA 4DWGA 3N3LF 3WSBA 4OMGA 2RAHA 2ONGA 5AHUB 1YJ4A 1VG7A 4LLTA 4JYXA 3WE9A 2Q9YA 3TFNA 5IK6A 3ICZA 3QQVA 3P8RA 3VJCA 3ACYA 3LEEA 4NFIF 2ZEUA 1N1ZA 4LOBA 5ILHA 3KB9A 4ZQ8A 3EGTA 5B0KA 3WEJA 1YYSA 1N23A 3N0FA 2F9KF 3LOMA 4PVXF 3WEHA 4MC0A 4LUUA 3M00A 2F94F 4GA3A 5JV0F 3CC9A 5EATA 5JUZF 4NG6A 4H5EF 3P5RA 3OACB 2Q9ZA 3ICNA 4F6VA 3WJNA 3OABA 3Q2ZA 4UMJA 2QISA 3WCDA 3Q30A 3LDWA 4RXEA 5B0JA 2AZKA 3ACWA 3KRFA 5A0KA 5EAUA 1V4JA 4DZWA 2AETA 3B7LA 3WCLA 5CG5A 2ZCQA 2AEKA 1PS1A 5DHKA 4OKMA 3TFVA 2ZCRA 5CG6A 5DJPF 2ZCOA 4LIXA 4P0VA 2Z4ZA 3APZA 3P8LA 4XQTF 3PKOA 1EZFA 3NRIA 5A0IA 5A0JA 3V1XA 3N49F 4FP4A 4KWDA 2O1OA 1KIZA 4LZ3A 1UBVA 3ZCDA 4OGUA 4PVYF 4LPGF 3M0GA 3SDVA 3VJ8A 3W7FA 2PS5A 4HD1A 4DEMF 4P0XA 2E8TA 2J1OA 2E90A 2Z7HA 3RMGA 3NF2A 4WK5A 1WL3A 1N20A 2Z4WA 5DGMF 4L2XF 4F6XA 5ERMA 3OABB 2EWGA 1FPSA 5B0MA 3PYBA 4RNQA 5B01A 2OPMA 3KRFB 1YYTA 4DWBA 2E8XA 1YYUA 3LGKA 4DHDA 3IPIA 5EASA 4RXDA 3LZ9A 3IBAA 3VJEA 5IKHA 5IM1A 1WL0A 4KVIA 1JFAA 3EFQA 4KPJA 5DGSF 3RYWA 1HXAA 5IK0A 4LPHF 3N5JF 2I19A 3DYFA 4LXWA 1V4IA 5IMPA 3SDTA 2F8CF 5HN7A 4KQSA 2Z4VA 3PDEA 2Z50A 3N6KF 4DXJA 3WC9A 3SDRA 5HN8A 1WL2A 5DGNF 2FTZA 2AZLA 4LFEA 1YYRA 3SDQA 3WJKA 5ILKA 3AE0A 1YHLA 4MC8A 3VJDA 3WCEA 4KKMA 2F8ZF 1WKZA 1RQJA 1JFGA 2E93A 2Q80A 4JXYA 4GAXA 3WEFA 4GP1A 1HM7A 4KQUA 2E8VA 3KROA 5DIQF 3KRAA 3N0GA 3WCCA 4JZBA 3V66A 5IMNA 2F7MF 2ONHA 3ADZA 3RYEA 5AELA 4LZ0A 3AQCB 3WCAA 5IK9A 3M01A 5B0LA 3WSAA 3WCIA 5DJVF 3KRCA 4KVWA 1YV5A 4N9UA 3ACXA 5ILIA 3WJOA 4OKZA 4NUAA 4LTZA 3LLWA 2ZY1A 2FORA 3AQBB 4LTVA 4KVYA 4DI5A 4KVDA 2PS4A 4QPFA 4QXSF 5ER8A 3BNXA 2P1CA 4RYPA 2Z4XA 4KK2A 5E8LA 2Z78A 3BNYA 2E91A 3WEKA 2VF6A 2E8UA 3EZ3A 5IL8A 1UBXA 1DI1A 4NFKF 4NFJF 4JZXA 5B0IA 4E9UA 3WCBA 1WL1A 4MC3A 4EA2A 3NPRA 1WY0A 4EA0A 2OGDA 3KROB 3SDUA 3KRAB 3DYHA 3RBMA 5DZ2A 1HM4A 3WEGA 3TS7A 2E92A 5DHIA 2E95A 3M9UA 4H5CF 3VJAA 5B02A 3LGZB 3AQ0A 4KPDA 3LVSA 5HN9A 3WCFA 3KRCB 1N24A 2E8WA 4E9ZA 2F92F 3N45F 3LK5A 4OMHA 2PS8A 4LA6A 3WEIA 4NKFA 4LZCA 2Z7IA 5JV1F 3N46F 4LFVF 3NPKA 2J1PA 3Q1OA 4RXCA 5JA0F 3TFPA 5ILZA 1V4EA 4LFGA 3CP6A 4E1EA 4P0WA 3UCAA 5E8HA
chains in the Genus database with same CATH topology
4JXNA 5ILYA 5I1UA 2ZEVA 5IVGA 5C05A 1YHKA 4F62A 5B00A 4XQRF 2OPNA 5B03A 3MAVA 3LMDA 3ZMCA 2PS7A 3G4DA 3LSNA 3WCGA 5HNAA 3DYGA 2PS6A 1N21A 1DGPA 3VJ9A 1VG2A 2ZCSA 3CKEA 3KRPA 2F89F 3WCHA 4EA1A 5IMIA 5ILDA 5H9DA 2AZJA 2DH4A 1VG4A 3Q2QA 3N5HF 3QKCA 5ERNA 1HXCA 3S4JA 4KQ5A 3VJBA 1VG3A 1WMWA 4K10A 5E8KA 3ICMA 5KSXF 3KBKA 1N22A 3ZOUA 4KUXA 5AYPA 5JV2F 1RQIA 3ASXA 3P41A 4H5DF 1KIYA 2Q58A 3SAEA 5ILJA 1N1BA 2Z4YA 3ZMBA 1YYQA 3ID0A 3N3DA 1YHMA 4GP2A 1UBWA 3LJIA 4LA5A 2E4OA 3PH7A 2Z52A 3PYAA 1YQ7A 4KFAA 4N1ZF 3LG5A 3G4FA 4LLSA 4FJQA 1UBYA 4RXAA 1VG6A 2E94A 1HXGA 3P5PA 1ZW5A 1V4KA 3MZVA 3ZL6A 3TC1A 3KRPB 3V1VA 4XQSF 5DJRF 1RTRA 3M02A 4NKEA 5AFXA 3OYRA 3N1VF 3WCMA 5IN8A 3S9VA 4JVJF 3WCJA 2OA6A 3ICKA 2AELA 4Q23A 1HX9A 1V4HA 5IL3A 2H8OA 5DW7A 3N1WF 3OACA 5EROA 2J5CA 5IKAA 4DWGA 3N3LF 3WSBA 4OMGA 2RAHA 2ONGA 5AHUB 1YJ4A 1VG7A 4LLTA 4JYXA 3WE9A 2Q9YA 3TFNA 5IK6A 3ICZA 3QQVA 3P8RA 3VJCA 3ACYA 3LEEA 4NFIF 2ZEUA 1N1ZA 4LOBA 5ILHA 3KB9A 4ZQ8A 3EGTA 5B0KA 3WEJA 1YYSA 1N23A 3N0FA 2F9KF 3LOMA 4PVXF 3WEHA 4MC0A 4LUUA 3M00A 2F94F 4GA3A 5JV0F 3CC9A 5EATA 5JUZF 4NG6A 4H5EF 3P5RA 3OACB 2Q9ZA 3ICNA 4F6VA 3WJNA 3OABA 3Q2ZA 4UMJA 2QISA 3WCDA 3Q30A 3LDWA 4RXEA 5B0JA 2AZKA 3ACWA 3KRFA 5A0KA 5EAUA 1V4JA 4DZWA 2AETA 3B7LA 3WCLA 5CG5A 2ZCQA 2AEKA 1PS1A 5DHKA 4OKMA 3TFVA 2ZCRA 5CG6A 5DJPF 2ZCOA 4LIXA 4P0VA 2Z4ZA 3APZA 3P8LA 4XQTF 3PKOA 1EZFA 3NRIA 5A0IA 5A0JA 3V1XA 3N49F 4FP4A 4KWDA 2O1OA 1KIZA 4LZ3A 1UBVA 3ZCDA 4OGUA 4PVYF 4LPGF 3M0GA 3SDVA 3VJ8A 3W7FA 2PS5A 4HD1A 4DEMF 4P0XA 2E8TA 2J1OA 2E90A 2Z7HA 3RMGA 3NF2A 4WK5A 1WL3A 1N20A 2Z4WA 5DGMF 4L2XF 4F6XA 5ERMA 3OABB 2EWGA 1FPSA 5B0MA 3PYBA 4RNQA 5B01A 2OPMA 3KRFB 1YYTA 4DWBA 2E8XA 1YYUA 3LGKA 4DHDA 3IPIA 5EASA 4RXDA 3LZ9A 3IBAA 3VJEA 5IKHA 5IM1A 1WL0A 4KVIA 1JFAA 3EFQA 4KPJA 5DGSF 3RYWA 1HXAA 5IK0A 4LPHF 3N5JF 2I19A 3DYFA 4LXWA 1V4IA 5IMPA 3SDTA 2F8CF 5HN7A 4KQSA 2Z4VA 3PDEA 2Z50A 3N6KF 4DXJA 3WC9A 3SDRA 5HN8A 1WL2A 5DGNF 2FTZA 2AZLA 4LFEA 1YYRA 3SDQA 3WJKA 5ILKA 3AE0A 1YHLA 4MC8A 3VJDA 3WCEA 4KKMA 2F8ZF 1WKZA 1RQJA 1JFGA 2E93A 2Q80A 4JXYA 4GAXA 3WEFA 4GP1A 1HM7A 4KQUA 2E8VA 3KROA 5DIQF 3KRAA 3N0GA 3WCCA 4JZBA 3V66A 5IMNA 2F7MF 2ONHA 3ADZA 3RYEA 5AELA 4LZ0A 3AQCB 3WCAA 5IK9A 3M01A 5B0LA 3WSAA 3WCIA 5DJVF 3KRCA 4KVWA 1YV5A 4N9UA 3ACXA 5ILIA 3WJOA 4OKZA 4NUAA 4LTZA 3LLWA 2ZY1A 2FORA 3AQBB 4LTVA 4KVYA 4DI5A 4KVDA 2PS4A 4QPFA 4QXSF 5ER8A 3BNXA 2P1CA 4RYPA 2Z4XA 4KK2A 5E8LA 2Z78A 3BNYA 2E91A 3WEKA 2VF6A 2E8UA 3EZ3A 5IL8A 1UBXA 1DI1A 4NFKF 4NFJF 4JZXA 5B0IA 4E9UA 3WCBA 1WL1A 4MC3A 4EA2A 3NPRA 1WY0A 4EA0A 2OGDA 3KROB 3SDUA 3KRAB 3DYHA 3RBMA 5DZ2A 1HM4A 3WEGA 3TS7A 2E92A 5DHIA 2E95A 3M9UA 4H5CF 3VJAA 5B02A 3LGZB 3AQ0A 4KPDA 3LVSA 5HN9A 3WCFA 3KRCB 1N24A 2E8WA 4E9ZA 2F92F 3N45F 3LK5A 4OMHA 2PS8A 4LA6A 3WEIA 4NKFA 4LZCA 2Z7IA 5JV1F 3N46F 4LFVF 3NPKA 2J1PA 3Q1OA 4RXCA 5JA0F 3TFPA 5ILZA 1V4EA 4LFGA 3CP6A 4E1EA 4P0WA 3UCAA 5E8HA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4JXN A;  5ILY A;  5I1U A;  2ZEV A;  5IVG A;  5C05 A;  1YHK A;  4F62 A;  5B00 A;  4XQR F;  2OPN A;  5B03 A;  3MAV A;  3LMD A;  3ZMC A;  2PS7 A;  3G4D A;  3LSN A;  3WCG A;  5HNA A;  3DYG A;  2PS6 A;  1N21 A;  1DGP A;  3VJ9 A;  1VG2 A;  2ZCS A;  3CKE A;  3KRP A;  2F89 F;  3WCH A;  4EA1 A;  5IMI A;  5ILD A;  5H9D A;  2AZJ A;  2DH4 A;  1VG4 A;  3Q2Q A;  3N5H F;  3QKC A;  5ERN A;  1HXC A;  3S4J A;  4KQ5 A;  3VJB A;  1VG3 A;  1WMW A;  4K10 A;  5E8K A;  3ICM A;  5KSX F;  3KBK A;  1N22 A;  3ZOU A;  4KUX A;  5AYP A;  5JV2 F;  1RQI A;  3ASX A;  3P41 A;  4H5D F;  1KIY A;  2Q58 A;  3SAE A;  5ILJ A;  1N1B A;  2Z4Y A;  3ZMB A;  1YYQ A;  3ID0 A;  3N3D A;  1YHM A;  4GP2 A;  1UBW A;  3LJI A;  4LA5 A;  2E4O A;  3PH7 A;  2Z52 A;  3PYA A;  1YQ7 A;  4KFA A;  4N1Z F;  3LG5 A;  3G4F A;  4LLS A;  4FJQ A;  1UBY A;  4RXA A;  1VG6 A;  2E94 A;  1HXG A;  3P5P A;  1ZW5 A;  1V4K A;  3MZV A;  3ZL6 A;  3TC1 A;  3KRP B;  3V1V A;  4XQS F;  5DJR F;  1RTR A;  3M02 A;  4NKE A;  5AFX A;  3OYR A;  3N1V F;  3WCM A;  5IN8 A;  3S9V A;  4JVJ F;  3WCJ A;  2OA6 A;  3ICK A;  2AEL A;  4Q23 A;  1HX9 A;  1V4H A;  5IL3 A;  2H8O A;  5DW7 A;  3N1W F;  3OAC A;  5ERO A;  2J5C A;  5IKA A;  4DWG A;  3N3L F;  3WSB A;  4OMG A;  2RAH A;  2ONG A;  5AHU B;  1YJ4 A;  1VG7 A;  4LLT A;  4JYX A;  3WE9 A;  2Q9Y A;  3TFN A;  5IK6 A;  3ICZ A;  3QQV A;  3P8R A;  3VJC A;  3ACY A;  3LEE A;  4NFI F;  2ZEU A;  1N1Z A;  4LOB A;  5ILH A;  3KB9 A;  4ZQ8 A;  3EGT A;  5B0K A;  3WEJ A;  1YYS A;  1N23 A;  3N0F A;  2F9K F;  3LOM A;  4PVX F;  3WEH A;  4MC0 A;  4LUU A;  3M00 A;  2F94 F;  4GA3 A;  5JV0 F;  3CC9 A;  5EAT A;  5JUZ F;  4NG6 A;  4H5E F;  3P5R A;  3OAC B;  2Q9Z A;  3ICN A;  4F6V A;  3WJN A;  3OAB A;  3Q2Z A;  4UMJ A;  2QIS A;  3WCD A;  3Q30 A;  3LDW A;  4RXE A;  5B0J A;  2AZK A;  3ACW A;  3KRF A;  5A0K A;  5EAU A;  1V4J A;  4DZW A;  2AET A;  3B7L A;  3WCL A;  5CG5 A;  2ZCQ A;  2AEK A;  1PS1 A;  5DHK A;  4OKM A;  3TFV A;  2ZCR A;  5CG6 A;  5DJP F;  2ZCO A;  4LIX A;  4P0V A;  2Z4Z A;  3APZ A;  3P8L A;  4XQT F;  3PKO A;  1EZF A;  3NRI A;  5A0I A;  5A0J A;  3V1X A;  3N49 F;  4FP4 A;  4KWD A;  2O1O A;  1KIZ A;  4LZ3 A;  1UBV A;  3ZCD A;  4OGU A;  4PVY F;  4LPG F;  3M0G A;  3SDV A;  3VJ8 A;  3W7F A;  2PS5 A;  4HD1 A;  4DEM F;  4P0X A;  2E8T A;  2J1O A;  2E90 A;  2Z7H A;  3RMG A;  3NF2 A;  4WK5 A;  1WL3 A;  1N20 A;  2Z4W A;  5DGM F;  4L2X F;  4F6X A;  5ERM A;  3OAB B;  2EWG A;  1FPS A;  5B0M A;  3PYB A;  4RNQ A;  5B01 A;  2OPM A;  3KRF B;  1YYT A;  4DWB A;  2E8X A;  1YYU A;  3LGK A;  4DHD A;  3IPI A;  5EAS A;  4RXD A;  3LZ9 A;  3IBA A;  3VJE A;  5IKH A;  5IM1 A;  1WL0 A;  4KVI A;  1JFA A;  3EFQ A;  4KPJ A;  5DGS F;  3RYW A;  1HXA A;  5IK0 A;  4LPH F;  3N5J F;  2I19 A;  3DYF A;  4LXW A;  1V4I A;  5IMP A;  3SDT A;  2F8C F;  5HN7 A;  4KQS A;  2Z4V A;  3PDE A;  2Z50 A;  3N6K F;  4DXJ A;  3WC9 A;  3SDR A;  5HN8 A;  1WL2 A;  5DGN F;  2FTZ A;  2AZL A;  4LFE A;  1YYR A;  3SDQ A;  3WJK A;  5ILK A;  3AE0 A;  1YHL A;  4MC8 A;  3VJD A;  3WCE A;  4KKM A;  2F8Z F;  1WKZ A;  1RQJ A;  1JFG A;  2E93 A;  2Q80 A;  4JXY A;  4GAX A;  3WEF A;  4GP1 A;  1HM7 A;  4KQU A;  2E8V A;  3KRO A;  5DIQ F;  3KRA A;  3N0G A;  3WCC A;  4JZB A;  3V66 A;  5IMN A;  2F7M F;  2ONH A;  3ADZ A;  3RYE A;  5AEL A;  4LZ0 A;  3AQC B;  3WCA A;  5IK9 A;  3M01 A;  5B0L A;  3WSA A;  3WCI A;  5DJV F;  3KRC A;  4KVW A;  1YV5 A;  4N9U A;  3ACX A;  5ILI A;  3WJO A;  4OKZ A;  4NUA A;  4LTZ A;  3LLW A;  2ZY1 A;  2FOR A;  3AQB B;  4LTV A;  4KVY A;  4DI5 A;  4KVD A;  2PS4 A;  4QPF A;  4QXS F;  5ER8 A;  3BNX A;  2P1C A;  4RYP A;  2Z4X A;  4KK2 A;  5E8L A;  2Z78 A;  3BNY A;  2E91 A;  3WEK A;  2VF6 A;  2E8U A;  3EZ3 A;  5IL8 A;  1UBX A;  1DI1 A;  4NFK F;  4NFJ F;  4JZX A;  5B0I A;  4E9U A;  3WCB A;  1WL1 A;  4MC3 A;  4EA2 A;  3NPR A;  1WY0 A;  4EA0 A;  2OGD A;  3KRO B;  3SDU A;  3KRA B;  3DYH A;  3RBM A;  5DZ2 A;  1HM4 A;  3WEG A;  3TS7 A;  2E92 A;  5DHI A;  2E95 A;  3M9U A;  4H5C F;  3VJA A;  5B02 A;  3LGZ B;  3AQ0 A;  4KPD A;  3LVS A;  5HN9 A;  3WCF A;  3KRC B;  1N24 A;  2E8W A;  4E9Z A;  2F92 F;  3N45 F;  3LK5 A;  4OMH A;  2PS8 A;  4LA6 A;  3WEI A;  4NKF A;  4LZC A;  2Z7I A;  5JV1 F;  3N46 F;  4LFV F;  3NPK A;  2J1P A;  3Q1O A;  4RXC A;  5JA0 F;  3TFP A;  5ILZ A;  1V4E A;  4LFG A;  3CP6 A;  4E1E A;  4P0W A;  3UCA A;  5E8H A; 
#chains in the Genus database with same CATH topology
 4JXN A;  5ILY A;  5I1U A;  2ZEV A;  5IVG A;  5C05 A;  1YHK A;  4F62 A;  5B00 A;  4XQR F;  2OPN A;  5B03 A;  3MAV A;  3LMD A;  3ZMC A;  2PS7 A;  3G4D A;  3LSN A;  3WCG A;  5HNA A;  3DYG A;  2PS6 A;  1N21 A;  1DGP A;  3VJ9 A;  1VG2 A;  2ZCS A;  3CKE A;  3KRP A;  2F89 F;  3WCH A;  4EA1 A;  5IMI A;  5ILD A;  5H9D A;  2AZJ A;  2DH4 A;  1VG4 A;  3Q2Q A;  3N5H F;  3QKC A;  5ERN A;  1HXC A;  3S4J A;  4KQ5 A;  3VJB A;  1VG3 A;  1WMW A;  4K10 A;  5E8K A;  3ICM A;  5KSX F;  3KBK A;  1N22 A;  3ZOU A;  4KUX A;  5AYP A;  5JV2 F;  1RQI A;  3ASX A;  3P41 A;  4H5D F;  1KIY A;  2Q58 A;  3SAE A;  5ILJ A;  1N1B A;  2Z4Y A;  3ZMB A;  1YYQ A;  3ID0 A;  3N3D A;  1YHM A;  4GP2 A;  1UBW A;  3LJI A;  4LA5 A;  2E4O A;  3PH7 A;  2Z52 A;  3PYA A;  1YQ7 A;  4KFA A;  4N1Z F;  3LG5 A;  3G4F A;  4LLS A;  4FJQ A;  1UBY A;  4RXA A;  1VG6 A;  2E94 A;  1HXG A;  3P5P A;  1ZW5 A;  1V4K A;  3MZV A;  3ZL6 A;  3TC1 A;  3KRP B;  3V1V A;  4XQS F;  5DJR F;  1RTR A;  3M02 A;  4NKE A;  5AFX A;  3OYR A;  3N1V F;  3WCM A;  5IN8 A;  3S9V A;  4JVJ F;  3WCJ A;  2OA6 A;  3ICK A;  2AEL A;  4Q23 A;  1HX9 A;  1V4H A;  5IL3 A;  2H8O A;  5DW7 A;  3N1W F;  3OAC A;  5ERO A;  2J5C A;  5IKA A;  4DWG A;  3N3L F;  3WSB A;  4OMG A;  2RAH A;  2ONG A;  5AHU B;  1YJ4 A;  1VG7 A;  4LLT A;  4JYX A;  3WE9 A;  2Q9Y A;  3TFN A;  5IK6 A;  3ICZ A;  3QQV A;  3P8R A;  3VJC A;  3ACY A;  3LEE A;  4NFI F;  2ZEU A;  1N1Z A;  4LOB A;  5ILH A;  3KB9 A;  4ZQ8 A;  3EGT A;  5B0K A;  3WEJ A;  1YYS A;  1N23 A;  3N0F A;  2F9K F;  3LOM A;  4PVX F;  3WEH A;  4MC0 A;  4LUU A;  3M00 A;  2F94 F;  4GA3 A;  5JV0 F;  3CC9 A;  5EAT A;  5JUZ F;  4NG6 A;  4H5E F;  3P5R A;  3OAC B;  2Q9Z A;  3ICN A;  4F6V A;  3WJN A;  3OAB A;  3Q2Z A;  4UMJ A;  2QIS A;  3WCD A;  3Q30 A;  3LDW A;  4RXE A;  5B0J A;  2AZK A;  3ACW A;  3KRF A;  5A0K A;  5EAU A;  1V4J A;  4DZW A;  2AET A;  3B7L A;  3WCL A;  5CG5 A;  2ZCQ A;  2AEK A;  1PS1 A;  5DHK A;  4OKM A;  3TFV A;  2ZCR A;  5CG6 A;  5DJP F;  2ZCO A;  4LIX A;  4P0V A;  2Z4Z A;  3APZ A;  3P8L A;  4XQT F;  3PKO A;  1EZF A;  3NRI A;  5A0I A;  5A0J A;  3V1X A;  3N49 F;  4FP4 A;  4KWD A;  2O1O A;  1KIZ A;  4LZ3 A;  1UBV A;  3ZCD A;  4OGU A;  4PVY F;  4LPG F;  3M0G A;  3SDV A;  3VJ8 A;  3W7F A;  2PS5 A;  4HD1 A;  4DEM F;  4P0X A;  2E8T A;  2J1O A;  2E90 A;  2Z7H A;  3RMG A;  3NF2 A;  4WK5 A;  1WL3 A;  1N20 A;  2Z4W A;  5DGM F;  4L2X F;  4F6X A;  5ERM A;  3OAB B;  2EWG A;  1FPS A;  5B0M A;  3PYB A;  4RNQ A;  5B01 A;  2OPM A;  3KRF B;  1YYT A;  4DWB A;  2E8X A;  1YYU A;  3LGK A;  4DHD A;  3IPI A;  5EAS A;  4RXD A;  3LZ9 A;  3IBA A;  3VJE A;  5IKH A;  5IM1 A;  1WL0 A;  4KVI A;  1JFA A;  3EFQ A;  4KPJ A;  5DGS F;  3RYW A;  1HXA A;  5IK0 A;  4LPH F;  3N5J F;  2I19 A;  3DYF A;  4LXW A;  1V4I A;  5IMP A;  3SDT A;  2F8C F;  5HN7 A;  4KQS A;  2Z4V A;  3PDE A;  2Z50 A;  3N6K F;  4DXJ A;  3WC9 A;  3SDR A;  5HN8 A;  1WL2 A;  5DGN F;  2FTZ A;  2AZL A;  4LFE A;  1YYR A;  3SDQ A;  3WJK A;  5ILK A;  3AE0 A;  1YHL A;  4MC8 A;  3VJD A;  3WCE A;  4KKM A;  2F8Z F;  1WKZ A;  1RQJ A;  1JFG A;  2E93 A;  2Q80 A;  4JXY A;  4GAX A;  3WEF A;  4GP1 A;  1HM7 A;  4KQU A;  2E8V A;  3KRO A;  5DIQ F;  3KRA A;  3N0G A;  3WCC A;  4JZB A;  3V66 A;  5IMN A;  2F7M F;  2ONH A;  3ADZ A;  3RYE A;  5AEL A;  4LZ0 A;  3AQC B;  3WCA A;  5IK9 A;  3M01 A;  5B0L A;  3WSA A;  3WCI A;  5DJV F;  3KRC A;  4KVW A;  1YV5 A;  4N9U A;  3ACX A;  5ILI A;  3WJO A;  4OKZ A;  4NUA A;  4LTZ A;  3LLW A;  2ZY1 A;  2FOR A;  3AQB B;  4LTV A;  4KVY A;  4DI5 A;  4KVD A;  2PS4 A;  4QPF A;  4QXS F;  5ER8 A;  3BNX A;  2P1C A;  4RYP A;  2Z4X A;  4KK2 A;  5E8L A;  2Z78 A;  3BNY A;  2E91 A;  3WEK A;  2VF6 A;  2E8U A;  3EZ3 A;  5IL8 A;  1UBX A;  1DI1 A;  4NFK F;  4NFJ F;  4JZX A;  5B0I A;  4E9U A;  3WCB A;  1WL1 A;  4MC3 A;  4EA2 A;  3NPR A;  1WY0 A;  4EA0 A;  2OGD A;  3KRO B;  3SDU A;  3KRA B;  3DYH A;  3RBM A;  5DZ2 A;  1HM4 A;  3WEG A;  3TS7 A;  2E92 A;  5DHI A;  2E95 A;  3M9U A;  4H5C F;  3VJA A;  5B02 A;  3LGZ B;  3AQ0 A;  4KPD A;  3LVS A;  5HN9 A;  3WCF A;  3KRC B;  1N24 A;  2E8W A;  4E9Z A;  2F92 F;  3N45 F;  3LK5 A;  4OMH A;  2PS8 A;  4LA6 A;  3WEI A;  4NKF A;  4LZC A;  2Z7I A;  5JV1 F;  3N46 F;  4LFV F;  3NPK A;  2J1P A;  3Q1O A;  4RXC A;  5JA0 F;  3TFP A;  5ILZ A;  1V4E A;  4LFG A;  3CP6 A;  4E1E A;  4P0W A;  3UCA A;  5E8H A; 
#chains in the Genus database with same CATH homology
 4JXN A;  5ILY A;  5I1U A;  2ZEV A;  5IVG A;  5C05 A;  1YHK A;  4F62 A;  5B00 A;  4XQR F;  2OPN A;  5B03 A;  3MAV A;  3LMD A;  3ZMC A;  2PS7 A;  3G4D A;  3LSN A;  3WCG A;  5HNA A;  3DYG A;  2PS6 A;  1N21 A;  1DGP A;  3VJ9 A;  1VG2 A;  2ZCS A;  3CKE A;  3KRP A;  2F89 F;  3WCH A;  4EA1 A;  5IMI A;  5ILD A;  5H9D A;  2AZJ A;  2DH4 A;  1VG4 A;  3Q2Q A;  3N5H F;  3QKC A;  5ERN A;  1HXC A;  3S4J A;  4KQ5 A;  3VJB A;  1VG3 A;  1WMW A;  4K10 A;  5E8K A;  3ICM A;  5KSX F;  3KBK A;  1N22 A;  3ZOU A;  4KUX A;  5AYP A;  5JV2 F;  1RQI A;  3ASX A;  3P41 A;  4H5D F;  1KIY A;  2Q58 A;  3SAE A;  5ILJ A;  1N1B A;  2Z4Y A;  3ZMB A;  1YYQ A;  3ID0 A;  3N3D A;  1YHM A;  4GP2 A;  1UBW A;  3LJI A;  4LA5 A;  2E4O A;  3PH7 A;  2Z52 A;  3PYA A;  1YQ7 A;  4KFA A;  4N1Z F;  3LG5 A;  3G4F A;  4LLS A;  4FJQ A;  1UBY A;  4RXA A;  1VG6 A;  2E94 A;  1HXG A;  3P5P A;  1ZW5 A;  1V4K A;  3MZV A;  3ZL6 A;  3TC1 A;  3KRP B;  3V1V A;  4XQS F;  5DJR F;  1RTR A;  3M02 A;  4NKE A;  5AFX A;  3OYR A;  3N1V F;  3WCM A;  5IN8 A;  3S9V A;  4JVJ F;  3WCJ A;  2OA6 A;  3ICK A;  2AEL A;  4Q23 A;  1HX9 A;  1V4H A;  5IL3 A;  2H8O A;  5DW7 A;  3N1W F;  3OAC A;  5ERO A;  2J5C A;  5IKA A;  4DWG A;  3N3L F;  3WSB A;  4OMG A;  2RAH A;  2ONG A;  5AHU B;  1YJ4 A;  1VG7 A;  4LLT A;  4JYX A;  3WE9 A;  2Q9Y A;  3TFN A;  5IK6 A;  3ICZ A;  3QQV A;  3P8R A;  3VJC A;  3ACY A;  3LEE A;  4NFI F;  2ZEU A;  1N1Z A;  4LOB A;  5ILH A;  3KB9 A;  4ZQ8 A;  3EGT A;  5B0K A;  3WEJ A;  1YYS A;  1N23 A;  3N0F A;  2F9K F;  3LOM A;  4PVX F;  3WEH A;  4MC0 A;  4LUU A;  3M00 A;  2F94 F;  4GA3 A;  5JV0 F;  3CC9 A;  5EAT A;  5JUZ F;  4NG6 A;  4H5E F;  3P5R A;  3OAC B;  2Q9Z A;  3ICN A;  4F6V A;  3WJN A;  3OAB A;  3Q2Z A;  4UMJ A;  2QIS A;  3WCD A;  3Q30 A;  3LDW A;  4RXE A;  5B0J A;  2AZK A;  3ACW A;  3KRF A;  5A0K A;  5EAU A;  1V4J A;  4DZW A;  2AET A;  3B7L A;  3WCL A;  5CG5 A;  2ZCQ A;  2AEK A;  1PS1 A;  5DHK A;  4OKM A;  3TFV A;  2ZCR A;  5CG6 A;  5DJP F;  2ZCO A;  4LIX A;  4P0V A;  2Z4Z A;  3APZ A;  3P8L A;  4XQT F;  3PKO A;  1EZF A;  3NRI A;  5A0I A;  5A0J A;  3V1X A;  3N49 F;  4FP4 A;  4KWD A;  2O1O A;  1KIZ A;  4LZ3 A;  1UBV A;  3ZCD A;  4OGU A;  4PVY F;  4LPG F;  3M0G A;  3SDV A;  3VJ8 A;  3W7F A;  2PS5 A;  4HD1 A;  4DEM F;  4P0X A;  2E8T A;  2J1O A;  2E90 A;  2Z7H A;  3RMG A;  3NF2 A;  4WK5 A;  1WL3 A;  1N20 A;  2Z4W A;  5DGM F;  4L2X F;  4F6X A;  5ERM A;  3OAB B;  2EWG A;  1FPS A;  5B0M A;  3PYB A;  4RNQ A;  5B01 A;  2OPM A;  3KRF B;  1YYT A;  4DWB A;  2E8X A;  1YYU A;  3LGK A;  4DHD A;  3IPI A;  5EAS A;  4RXD A;  3LZ9 A;  3IBA A;  3VJE A;  5IKH A;  5IM1 A;  1WL0 A;  4KVI A;  1JFA A;  3EFQ A;  4KPJ A;  5DGS F;  3RYW A;  1HXA A;  5IK0 A;  4LPH F;  3N5J F;  2I19 A;  3DYF A;  4LXW A;  1V4I A;  5IMP A;  3SDT A;  2F8C F;  5HN7 A;  4KQS A;  2Z4V A;  3PDE A;  2Z50 A;  3N6K F;  4DXJ A;  3WC9 A;  3SDR A;  5HN8 A;  1WL2 A;  5DGN F;  2FTZ A;  2AZL A;  4LFE A;  1YYR A;  3SDQ A;  3WJK A;  5ILK A;  3AE0 A;  1YHL A;  4MC8 A;  3VJD A;  3WCE A;  4KKM A;  2F8Z F;  1WKZ A;  1RQJ A;  1JFG A;  2E93 A;  2Q80 A;  4JXY A;  4GAX A;  3WEF A;  4GP1 A;  1HM7 A;  4KQU A;  2E8V A;  3KRO A;  5DIQ F;  3KRA A;  3N0G A;  3WCC A;  4JZB A;  3V66 A;  5IMN A;  2F7M F;  2ONH A;  3ADZ A;  3RYE A;  5AEL A;  4LZ0 A;  3AQC B;  3WCA A;  5IK9 A;  3M01 A;  5B0L A;  3WSA A;  3WCI A;  5DJV F;  3KRC A;  4KVW A;  1YV5 A;  4N9U A;  3ACX A;  5ILI A;  3WJO A;  4OKZ A;  4NUA A;  4LTZ A;  3LLW A;  2ZY1 A;  2FOR A;  3AQB B;  4LTV A;  4KVY A;  4DI5 A;  4KVD A;  2PS4 A;  4QPF A;  4QXS F;  5ER8 A;  3BNX A;  2P1C A;  4RYP A;  2Z4X A;  4KK2 A;  5E8L A;  2Z78 A;  3BNY A;  2E91 A;  3WEK A;  2VF6 A;  2E8U A;  3EZ3 A;  5IL8 A;  1UBX A;  1DI1 A;  4NFK F;  4NFJ F;  4JZX A;  5B0I A;  4E9U A;  3WCB A;  1WL1 A;  4MC3 A;  4EA2 A;  3NPR A;  1WY0 A;  4EA0 A;  2OGD A;  3KRO B;  3SDU A;  3KRA B;  3DYH A;  3RBM A;  5DZ2 A;  1HM4 A;  3WEG A;  3TS7 A;  2E92 A;  5DHI A;  2E95 A;  3M9U A;  4H5C F;  3VJA A;  5B02 A;  3LGZ B;  3AQ0 A;  4KPD A;  3LVS A;  5HN9 A;  3WCF A;  3KRC B;  1N24 A;  2E8W A;  4E9Z A;  2F92 F;  3N45 F;  3LK5 A;  4OMH A;  2PS8 A;  4LA6 A;  3WEI A;  4NKF A;  4LZC A;  2Z7I A;  5JV1 F;  3N46 F;  4LFV F;  3NPK A;  2J1P A;  3Q1O A;  4RXC A;  5JA0 F;  3TFP A;  5ILZ A;  1V4E A;  4LFG A;  3CP6 A;  4E1E A;  4P0W A;  3UCA A;  5E8H A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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