5KSXF

Crystal structure of human fpps in complex with an allosteric inhibitor am-02-072
Total Genus 132
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
132
sequence length
343
structure length
339
Chain Sequence
VYAQEKQDFVQHFSQIVRVLTEGHPEIGDAIARLKEVLEYNAIGGKYNRGLTVVVAFRELVEPRKQDADSLQRAWTVGWCVELLQAFFLVADDIMDSSLTRRGQICWYQKPGVGLDAINDANLLEACIYRLLKLYCREQPYYLNLIELFLQSSYQTEIGQTLDLLTAPQNVDLVRFTEKRYKSIVKYKTAFYSFYLPIAAAMYMAGIDGEKEHANAKKILLEMGEFFQIQDDYLDLFGDPSVTGKIGTDIQDNKCSWLVVQCLQRATPEQYQILKENYGQKEAEKVARVKALYEELDLPAVFLQYEEDSYSHIMALIEQYAAPLPPAVFLGLARKIYKR
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Transferase/transferase inhibitor
molecule keywords Farnesyl pyrophosphate synthase
publication title Pharmacophore Mapping of Thienopyrimidine-Based Monophosphonate (ThP-MP) Inhibitors of the Human Farnesyl Pyrophosphate Synthase.
pubmed doi rcsb
source organism Homo sapiens
total genus 132
structure length 339
sequence length 343
ec nomenclature ec 2.5.1.1: Dimethylallyltranstransferase.
pdb deposition date 2016-07-10

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
F PF00348 polyprenyl_synt Polyprenyl synthetase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.600.10 Mainly Alpha Orthogonal Bundle Farnesyl Diphosphate Synthase Farnesyl Diphosphate Synthase 5ksxF00
5A0IA 4N1ZF 4E9ZA 2H8OA 1WMWA 1YV5A 2Z4XA 3N46F 5KSXF 5B0JA 3V66A 5JV1F 3M02A 3NPRA 4JXYA 2ZCRA 1YQ7A 3KRAB 4F62A 3CC9A 4LA5A 4OMGA 4KPDA 3TC1A 4L2XF 3WEKA 2P1CA 2Z4YA 4GP2A 3LK5A 2E8XA 2Q9ZA 1KIZA 3VJCA 3LGZB 5IK9A 5B0KA 4LIXA 3WEJA 4PVYF 2OPNA 1YYTA 5JV2F 3ICNA 2O1OA 1KIYA 4EA2A 3VJ9A 4DHDA 5JV0F 1WL2A 5EROA 1N21A 5IKHA 1WL3A 4DXJA 1UBVA 4JVJF 4KVDA 4LPHF 1FPSA 3ICMA 2ZCQA 4LFEA 2PS7A 3LOMA 5AFXA 3EGTA 1YHKA 2E94A 4DWGA 4LXWA 5IMNA 1YYRA 3OABA 3WCFA 3NF2A 4LTZA 3BNYA 5ILJA 2E90A 4GA3A 2AETA 3P8LA 3EFQA 3ACWA 2Z4VA 1HXAA 2ONGA 4KVIA 3V1VA 4MC0A 5ILZA 1VG7A 3EZ3A 2ZEVA 4F6VA 1HX9A 3ZCDA 3ACXA 4QPFA 5HN9A 2OGDA 3MZVA 3N0FA 3RBMA 4UMJA 3WCMA 5AELA 4LLTA 5EASA 3ZMCA 5E8HA 3RYEA 4DZWA 2ZEUA 1ZW5A 5B0IA 3WSAA 3N6KF 5ILDA 2F7MF 4QXSF 1PS1A 3RMGA 2E92A 5HNAA 4KQ5A 3TS7A 5DGSF 3DYGA 3OACA 3LDWA 3WCAA 1YJ4A 3VJEA 3KRCA 1V4IA 1RQJA 3QQVA 2E93A 3WCBA 4DWBA 4LTVA 5B02A 5ERMA 3WEFA 1V4JA 1V4EA 3WSBA 3LMDA 3APZA 3CP6A 5HN8A 3KROA 3N3DA 2F8CF 4OGUA 3LVSA 3OACB 3Q1OA 2Q9YA 3M0GA 4WK5A 1WY0A 2E95A 2E4OA 3WCDA 4NKFA 2Z78A 3WCCA 3WJKA 3WCIA 4DEMF 3SDVA 3LJIA 5B01A 4P0WA 1UBYA 3KROB 5JUZF 4KKMA 2Z50A 1DI1A 5HN7A 3BNXA 4NG6A 3DYFA 1UBXA 1YHMA 2PS6A 1VG2A 4K10A 3AQ0A 3WE9A 4KK2A 5ILKA 2E91A 4LZCA 3WEGA 3PYBA 3S4JA 3N1WF 4GAXA 3WCEA 4LUUA 5DIQF 4HD1A 3ICZA 4H5DF 3N49F 4NFIF 2Z52A 1VG3A 3N45F 5B0LA 5IVGA 3G4FA 2E8VA 4DI5A 4NFKF 3QKCA 2Q80A 1DGPA 5I1UA 3AQBB 5DJRF 4KVYA 4H5CF 1JFGA 1HM4A 2VF6A 3AE0A 5A0KA 5H9DA 3ACYA 2AZJA 1V4KA 3P8RA 2PS8A 3OABB 2F8ZF 5B00A 2OA6A 3VJDA 3TFVA 5DGMF 1N22A 3ID0A 3ASXA 4FJQA 4JYXA 4P0VA 4XQRF 5E8KA 3UCAA 3WJOA 3W7FA 5IM1A 4NKEA 4RXCA 3SAEA 3RYWA 4LFGA 5IK0A 5B0MA 5ILIA 4ZQ8A 2FORA 3KRFA 4LPGF 4XQTF 1HXCA 1HM7A 5C05A 1N23A 2Z4WA 5IN8A 3SDQA 1YHLA 4KQSA 3LLWA 3SDUA 1N1BA 3KBKA 2F89F 2OPMA 5DHKA 3Q30A 3AQCB 5A0JA 1N20A 3LG5A 4FP4A 3KRFB 5DHIA 5DJPF 2J1PA 4E9UA 3ZL6A 1N24A 1HXGA 4XQSF 4RNQA 5EATA 2AEKA 5E8LA 5IMPA 3NPKA 3SDTA 3ZMBA 4KPJA 4LZ0A 4EA1A 3G4DA 3N1VF 3PDEA 3Q2QA 4KQUA 3KRAA 2Z7IA 3KRCB 3VJ8A 3N0GA 5ILHA 4EA0A 4LLSA 2J5CA 3V1XA 2J1OA 5EAUA 3LGKA 3WCHA 3WCJA 2AELA 2EWGA 2Z4ZA 4GP1A 1EZFA 3PH7A 5ILYA 4KFAA 3NRIA 4LZ3A 1UBWA 4KUXA 3OYRA 2Z7HA 2F9KF 1VG4A 1WL0A 3M01A 3VJBA 4JXNA 3P5RA 5IK6A 3WCGA 4N9UA 4RXDA 5DJVF 3VJAA 2ZY1A 4RYPA 3LEEA 3KB9A 4JZXA 3PYAA 3WC9A 5AYPA 3S9VA 5DZ2A 4Q23A 3MAVA 3WEHA 1YYQA 5IL3A 3TFNA 3LZ9A 1YYSA 3WEIA 3WCLA 2ZCSA 5JA0F 3IBAA 3LSNA 3ADZA 3ICKA 4NFJF 5DGNF 3M9UA 5ER8A 3DYHA 3SDRA 4LOBA 4KVWA 2F94F 1YYUA 1VG6A 3N3LF 2FTZA 3P41A 4LA6A 4PVXF 5DW7A 3CKEA 4OMHA 3PKOA 4P0XA 5IL8A 1WL1A 2E8UA 5IKAA 2ZCOA 2I19A 5B03A 2QISA 3B7LA 3IPIA 4OKZA 2F92F 5AHUB 4LFVF 4RXEA 4H5EF 2DH4A 5IMIA 1WKZA 3N5HF 3P5PA 1RTRA 2Q58A 2RAHA 4E1EA 3KRPA 4F6XA 1JFAA 2PS5A 3M00A 1V4HA 2ONHA 3Q2ZA 4JZBA 3TFPA 1RQIA 4RXAA 3WJNA 5ERNA 4MC3A 4KWDA 2PS4A 1N1ZA 2E8WA 4MC8A 3N5JF 5CG5A 4NUAA 5CG6A 3KRPB 2E8TA 2AZKA 2AZLA 3ZOUA 4OKMA
chains in the Genus database with same CATH superfamily
5A0IA 4N1ZF 4E9ZA 2H8OA 1WMWA 1YV5A 2Z4XA 3N46F 5KSXF 5B0JA 3V66A 5JV1F 3M02A 3NPRA 4JXYA 2ZCRA 1YQ7A 3KRAB 4F62A 3CC9A 4LA5A 4OMGA 4KPDA 3TC1A 4L2XF 3WEKA 2P1CA 2Z4YA 4GP2A 3LK5A 2E8XA 2Q9ZA 1KIZA 3VJCA 3LGZB 5IK9A 5B0KA 4LIXA 3WEJA 4PVYF 2OPNA 1YYTA 5JV2F 3ICNA 2O1OA 1KIYA 4EA2A 3VJ9A 4DHDA 5JV0F 1WL2A 5EROA 1N21A 5IKHA 1WL3A 4DXJA 1UBVA 4JVJF 4KVDA 4LPHF 1FPSA 3ICMA 2ZCQA 4LFEA 2PS7A 3LOMA 5AFXA 3EGTA 1YHKA 2E94A 4DWGA 4LXWA 5IMNA 1YYRA 3OABA 3WCFA 3NF2A 4LTZA 3BNYA 5ILJA 2E90A 4GA3A 2AETA 3P8LA 3EFQA 3ACWA 2Z4VA 1HXAA 2ONGA 4KVIA 3V1VA 4MC0A 5ILZA 1VG7A 3EZ3A 2ZEVA 4F6VA 1HX9A 3ZCDA 3ACXA 4QPFA 5HN9A 2OGDA 3MZVA 3N0FA 3RBMA 4UMJA 3WCMA 5AELA 4LLTA 5EASA 3ZMCA 5E8HA 3RYEA 4DZWA 2ZEUA 1ZW5A 5B0IA 3WSAA 3N6KF 5ILDA 2F7MF 4QXSF 1PS1A 3RMGA 2E92A 5HNAA 4KQ5A 3TS7A 5DGSF 3DYGA 3OACA 3LDWA 3WCAA 1YJ4A 3VJEA 3KRCA 1V4IA 1RQJA 3QQVA 2E93A 3WCBA 4DWBA 4LTVA 5B02A 5ERMA 3WEFA 1V4JA 1V4EA 3WSBA 3LMDA 3APZA 3CP6A 5HN8A 3KROA 3N3DA 2F8CF 4OGUA 3LVSA 3OACB 3Q1OA 2Q9YA 3M0GA 4WK5A 1WY0A 2E95A 2E4OA 3WCDA 4NKFA 2Z78A 3WCCA 3WJKA 3WCIA 4DEMF 3SDVA 3LJIA 5B01A 4P0WA 1UBYA 3KROB 5JUZF 4KKMA 2Z50A 1DI1A 5HN7A 3BNXA 4NG6A 3DYFA 1UBXA 1YHMA 2PS6A 1VG2A 4K10A 3AQ0A 3WE9A 4KK2A 5ILKA 2E91A 4LZCA 3WEGA 3PYBA 3S4JA 3N1WF 4GAXA 3WCEA 4LUUA 5DIQF 4HD1A 3ICZA 4H5DF 3N49F 4NFIF 2Z52A 1VG3A 3N45F 5B0LA 5IVGA 3G4FA 2E8VA 4DI5A 4NFKF 3QKCA 2Q80A 1DGPA 5I1UA 3AQBB 5DJRF 4KVYA 4H5CF 1JFGA 1HM4A 2VF6A 3AE0A 5A0KA 5H9DA 3ACYA 2AZJA 1V4KA 3P8RA 2PS8A 3OABB 2F8ZF 5B00A 2OA6A 3VJDA 3TFVA 5DGMF 1N22A 3ID0A 3ASXA 4FJQA 4JYXA 4P0VA 4XQRF 5E8KA 3UCAA 3WJOA 3W7FA 5IM1A 4NKEA 4RXCA 3SAEA 3RYWA 4LFGA 5IK0A 5B0MA 5ILIA 4ZQ8A 2FORA 3KRFA 4LPGF 4XQTF 1HXCA 1HM7A 5C05A 1N23A 2Z4WA 5IN8A 3SDQA 1YHLA 4KQSA 3LLWA 3SDUA 1N1BA 3KBKA 2F89F 2OPMA 5DHKA 3Q30A 3AQCB 5A0JA 1N20A 3LG5A 4FP4A 3KRFB 5DHIA 5DJPF 2J1PA 4E9UA 3ZL6A 1N24A 1HXGA 4XQSF 4RNQA 5EATA 2AEKA 5E8LA 5IMPA 3NPKA 3SDTA 3ZMBA 4KPJA 4LZ0A 4EA1A 3G4DA 3N1VF 3PDEA 3Q2QA 4KQUA 3KRAA 2Z7IA 3KRCB 3VJ8A 3N0GA 5ILHA 4EA0A 4LLSA 2J5CA 3V1XA 2J1OA 5EAUA 3LGKA 3WCHA 3WCJA 2AELA 2EWGA 2Z4ZA 4GP1A 1EZFA 3PH7A 5ILYA 4KFAA 3NRIA 4LZ3A 1UBWA 4KUXA 3OYRA 2Z7HA 2F9KF 1VG4A 1WL0A 3M01A 3VJBA 4JXNA 3P5RA 5IK6A 3WCGA 4N9UA 4RXDA 5DJVF 3VJAA 2ZY1A 4RYPA 3LEEA 3KB9A 4JZXA 3PYAA 3WC9A 5AYPA 3S9VA 5DZ2A 4Q23A 3MAVA 3WEHA 1YYQA 5IL3A 3TFNA 3LZ9A 1YYSA 3WEIA 3WCLA 2ZCSA 5JA0F 3IBAA 3LSNA 3ADZA 3ICKA 4NFJF 5DGNF 3M9UA 5ER8A 3DYHA 3SDRA 4LOBA 4KVWA 2F94F 1YYUA 1VG6A 3N3LF 2FTZA 3P41A 4LA6A 4PVXF 5DW7A 3CKEA 4OMHA 3PKOA 4P0XA 5IL8A 1WL1A 2E8UA 5IKAA 2ZCOA 2I19A 5B03A 2QISA 3B7LA 3IPIA 4OKZA 2F92F 5AHUB 4LFVF 4RXEA 4H5EF 2DH4A 5IMIA 1WKZA 3N5HF 3P5PA 1RTRA 2Q58A 2RAHA 4E1EA 3KRPA 4F6XA 1JFAA 2PS5A 3M00A 1V4HA 2ONHA 3Q2ZA 4JZBA 3TFPA 1RQIA 4RXAA 3WJNA 5ERNA 4MC3A 4KWDA 2PS4A 1N1ZA 2E8WA 4MC8A 3N5JF 5CG5A 4NUAA 5CG6A 3KRPB 2E8TA 2AZKA 2AZLA 3ZOUA 4OKMA
chains in the Genus database with same CATH topology
5A0IA 4N1ZF 4E9ZA 2H8OA 1WMWA 1YV5A 2Z4XA 3N46F 5KSXF 5B0JA 3V66A 5JV1F 3M02A 3NPRA 4JXYA 2ZCRA 1YQ7A 3KRAB 4F62A 3CC9A 4LA5A 4OMGA 4KPDA 3TC1A 4L2XF 3WEKA 2P1CA 2Z4YA 4GP2A 3LK5A 2E8XA 2Q9ZA 1KIZA 3VJCA 3LGZB 5IK9A 5B0KA 4LIXA 3WEJA 4PVYF 2OPNA 1YYTA 5JV2F 3ICNA 2O1OA 1KIYA 4EA2A 3VJ9A 4DHDA 5JV0F 1WL2A 5EROA 1N21A 5IKHA 1WL3A 4DXJA 1UBVA 4JVJF 4KVDA 4LPHF 1FPSA 3ICMA 2ZCQA 4LFEA 2PS7A 3LOMA 5AFXA 3EGTA 1YHKA 2E94A 4DWGA 4LXWA 5IMNA 1YYRA 3OABA 3WCFA 3NF2A 4LTZA 3BNYA 5ILJA 2E90A 4GA3A 2AETA 3P8LA 3EFQA 3ACWA 2Z4VA 1HXAA 2ONGA 4KVIA 3V1VA 4MC0A 5ILZA 1VG7A 3EZ3A 2ZEVA 4F6VA 1HX9A 3ZCDA 3ACXA 4QPFA 5HN9A 2OGDA 3MZVA 3N0FA 3RBMA 4UMJA 3WCMA 5AELA 4LLTA 5EASA 3ZMCA 5E8HA 3RYEA 4DZWA 2ZEUA 1ZW5A 5B0IA 3WSAA 3N6KF 5ILDA 2F7MF 4QXSF 1PS1A 3RMGA 2E92A 5HNAA 4KQ5A 3TS7A 5DGSF 3DYGA 3OACA 3LDWA 3WCAA 1YJ4A 3VJEA 3KRCA 1V4IA 1RQJA 3QQVA 2E93A 3WCBA 4DWBA 4LTVA 5B02A 5ERMA 3WEFA 1V4JA 1V4EA 3WSBA 3LMDA 3APZA 3CP6A 5HN8A 3KROA 3N3DA 2F8CF 4OGUA 3LVSA 3OACB 3Q1OA 2Q9YA 3M0GA 4WK5A 1WY0A 2E95A 2E4OA 3WCDA 4NKFA 2Z78A 3WCCA 3WJKA 3WCIA 4DEMF 3SDVA 3LJIA 5B01A 4P0WA 1UBYA 3KROB 5JUZF 4KKMA 2Z50A 1DI1A 5HN7A 3BNXA 4NG6A 3DYFA 1UBXA 1YHMA 2PS6A 1VG2A 4K10A 3AQ0A 3WE9A 4KK2A 5ILKA 2E91A 4LZCA 3WEGA 3PYBA 3S4JA 3N1WF 4GAXA 3WCEA 4LUUA 5DIQF 4HD1A 3ICZA 4H5DF 3N49F 4NFIF 2Z52A 1VG3A 3N45F 5B0LA 5IVGA 3G4FA 2E8VA 4DI5A 4NFKF 3QKCA 2Q80A 1DGPA 5I1UA 3AQBB 5DJRF 4KVYA 4H5CF 1JFGA 1HM4A 2VF6A 3AE0A 5A0KA 5H9DA 3ACYA 2AZJA 1V4KA 3P8RA 2PS8A 3OABB 2F8ZF 5B00A 2OA6A 3VJDA 3TFVA 5DGMF 1N22A 3ID0A 3ASXA 4FJQA 4JYXA 4P0VA 4XQRF 5E8KA 3UCAA 3WJOA 3W7FA 5IM1A 4NKEA 4RXCA 3SAEA 3RYWA 4LFGA 5IK0A 5B0MA 5ILIA 4ZQ8A 2FORA 3KRFA 4LPGF 4XQTF 1HXCA 1HM7A 5C05A 1N23A 2Z4WA 5IN8A 3SDQA 1YHLA 4KQSA 3LLWA 3SDUA 1N1BA 3KBKA 2F89F 2OPMA 5DHKA 3Q30A 3AQCB 5A0JA 1N20A 3LG5A 4FP4A 3KRFB 5DHIA 5DJPF 2J1PA 4E9UA 3ZL6A 1N24A 1HXGA 4XQSF 4RNQA 5EATA 2AEKA 5E8LA 5IMPA 3NPKA 3SDTA 3ZMBA 4KPJA 4LZ0A 4EA1A 3G4DA 3N1VF 3PDEA 3Q2QA 4KQUA 3KRAA 2Z7IA 3KRCB 3VJ8A 3N0GA 5ILHA 4EA0A 4LLSA 2J5CA 3V1XA 2J1OA 5EAUA 3LGKA 3WCHA 3WCJA 2AELA 2EWGA 2Z4ZA 4GP1A 1EZFA 3PH7A 5ILYA 4KFAA 3NRIA 4LZ3A 1UBWA 4KUXA 3OYRA 2Z7HA 2F9KF 1VG4A 1WL0A 3M01A 3VJBA 4JXNA 3P5RA 5IK6A 3WCGA 4N9UA 4RXDA 5DJVF 3VJAA 2ZY1A 4RYPA 3LEEA 3KB9A 4JZXA 3PYAA 3WC9A 5AYPA 3S9VA 5DZ2A 4Q23A 3MAVA 3WEHA 1YYQA 5IL3A 3TFNA 3LZ9A 1YYSA 3WEIA 3WCLA 2ZCSA 5JA0F 3IBAA 3LSNA 3ADZA 3ICKA 4NFJF 5DGNF 3M9UA 5ER8A 3DYHA 3SDRA 4LOBA 4KVWA 2F94F 1YYUA 1VG6A 3N3LF 2FTZA 3P41A 4LA6A 4PVXF 5DW7A 3CKEA 4OMHA 3PKOA 4P0XA 5IL8A 1WL1A 2E8UA 5IKAA 2ZCOA 2I19A 5B03A 2QISA 3B7LA 3IPIA 4OKZA 2F92F 5AHUB 4LFVF 4RXEA 4H5EF 2DH4A 5IMIA 1WKZA 3N5HF 3P5PA 1RTRA 2Q58A 2RAHA 4E1EA 3KRPA 4F6XA 1JFAA 2PS5A 3M00A 1V4HA 2ONHA 3Q2ZA 4JZBA 3TFPA 1RQIA 4RXAA 3WJNA 5ERNA 4MC3A 4KWDA 2PS4A 1N1ZA 2E8WA 4MC8A 3N5JF 5CG5A 4NUAA 5CG6A 3KRPB 2E8TA 2AZKA 2AZLA 3ZOUA 4OKMA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5A0I A;  4N1Z F;  4E9Z A;  2H8O A;  1WMW A;  1YV5 A;  2Z4X A;  3N46 F;  5KSX F;  5B0J A;  3V66 A;  5JV1 F;  3M02 A;  3NPR A;  4JXY A;  2ZCR A;  1YQ7 A;  3KRA B;  4F62 A;  3CC9 A;  4LA5 A;  4OMG A;  4KPD A;  3TC1 A;  4L2X F;  3WEK A;  2P1C A;  2Z4Y A;  4GP2 A;  3LK5 A;  2E8X A;  2Q9Z A;  1KIZ A;  3VJC A;  3LGZ B;  5IK9 A;  5B0K A;  4LIX A;  3WEJ A;  4PVY F;  2OPN A;  1YYT A;  5JV2 F;  3ICN A;  2O1O A;  1KIY A;  4EA2 A;  3VJ9 A;  4DHD A;  5JV0 F;  1WL2 A;  5ERO A;  1N21 A;  5IKH A;  1WL3 A;  4DXJ A;  1UBV A;  4JVJ F;  4KVD A;  4LPH F;  1FPS A;  3ICM A;  2ZCQ A;  4LFE A;  2PS7 A;  3LOM A;  5AFX A;  3EGT A;  1YHK A;  2E94 A;  4DWG A;  4LXW A;  5IMN A;  1YYR A;  3OAB A;  3WCF A;  3NF2 A;  4LTZ A;  3BNY A;  5ILJ A;  2E90 A;  4GA3 A;  2AET A;  3P8L A;  3EFQ A;  3ACW A;  2Z4V A;  1HXA A;  2ONG A;  4KVI A;  3V1V A;  4MC0 A;  5ILZ A;  1VG7 A;  3EZ3 A;  2ZEV A;  4F6V A;  1HX9 A;  3ZCD A;  3ACX A;  4QPF A;  5HN9 A;  2OGD A;  3MZV A;  3N0F A;  3RBM A;  4UMJ A;  3WCM A;  5AEL A;  4LLT A;  5EAS A;  3ZMC A;  5E8H A;  3RYE A;  4DZW A;  2ZEU A;  1ZW5 A;  5B0I A;  3WSA A;  3N6K F;  5ILD A;  2F7M F;  4QXS F;  1PS1 A;  3RMG A;  2E92 A;  5HNA A;  4KQ5 A;  3TS7 A;  5DGS F;  3DYG A;  3OAC A;  3LDW A;  3WCA A;  1YJ4 A;  3VJE A;  3KRC A;  1V4I A;  1RQJ A;  3QQV A;  2E93 A;  3WCB A;  4DWB A;  4LTV A;  5B02 A;  5ERM A;  3WEF A;  1V4J A;  1V4E A;  3WSB A;  3LMD A;  3APZ A;  3CP6 A;  5HN8 A;  3KRO A;  3N3D A;  2F8C F;  4OGU A;  3LVS A;  3OAC B;  3Q1O A;  2Q9Y A;  3M0G A;  4WK5 A;  1WY0 A;  2E95 A;  2E4O A;  3WCD A;  4NKF A;  2Z78 A;  3WCC A;  3WJK A;  3WCI A;  4DEM F;  3SDV A;  3LJI A;  5B01 A;  4P0W A;  1UBY A;  3KRO B;  5JUZ F;  4KKM A;  2Z50 A;  1DI1 A;  5HN7 A;  3BNX A;  4NG6 A;  3DYF A;  1UBX A;  1YHM A;  2PS6 A;  1VG2 A;  4K10 A;  3AQ0 A;  3WE9 A;  4KK2 A;  5ILK A;  2E91 A;  4LZC A;  3WEG A;  3PYB A;  3S4J A;  3N1W F;  4GAX A;  3WCE A;  4LUU A;  5DIQ F;  4HD1 A;  3ICZ A;  4H5D F;  3N49 F;  4NFI F;  2Z52 A;  1VG3 A;  3N45 F;  5B0L A;  5IVG A;  3G4F A;  2E8V A;  4DI5 A;  4NFK F;  3QKC A;  2Q80 A;  1DGP A;  5I1U A;  3AQB B;  5DJR F;  4KVY A;  4H5C F;  1JFG A;  1HM4 A;  2VF6 A;  3AE0 A;  5A0K A;  5H9D A;  3ACY A;  2AZJ A;  1V4K A;  3P8R A;  2PS8 A;  3OAB B;  2F8Z F;  5B00 A;  2OA6 A;  3VJD A;  3TFV A;  5DGM F;  1N22 A;  3ID0 A;  3ASX A;  4FJQ A;  4JYX A;  4P0V A;  4XQR F;  5E8K A;  3UCA A;  3WJO A;  3W7F A;  5IM1 A;  4NKE A;  4RXC A;  3SAE A;  3RYW A;  4LFG A;  5IK0 A;  5B0M A;  5ILI A;  4ZQ8 A;  2FOR A;  3KRF A;  4LPG F;  4XQT F;  1HXC A;  1HM7 A;  5C05 A;  1N23 A;  2Z4W A;  5IN8 A;  3SDQ A;  1YHL A;  4KQS A;  3LLW A;  3SDU A;  1N1B A;  3KBK A;  2F89 F;  2OPM A;  5DHK A;  3Q30 A;  3AQC B;  5A0J A;  1N20 A;  3LG5 A;  4FP4 A;  3KRF B;  5DHI A;  5DJP F;  2J1P A;  4E9U A;  3ZL6 A;  1N24 A;  1HXG A;  4XQS F;  4RNQ A;  5EAT A;  2AEK A;  5E8L A;  5IMP A;  3NPK A;  3SDT A;  3ZMB A;  4KPJ A;  4LZ0 A;  4EA1 A;  3G4D A;  3N1V F;  3PDE A;  3Q2Q A;  4KQU A;  3KRA A;  2Z7I A;  3KRC B;  3VJ8 A;  3N0G A;  5ILH A;  4EA0 A;  4LLS A;  2J5C A;  3V1X A;  2J1O A;  5EAU A;  3LGK A;  3WCH A;  3WCJ A;  2AEL A;  2EWG A;  2Z4Z A;  4GP1 A;  1EZF A;  3PH7 A;  5ILY A;  4KFA A;  3NRI A;  4LZ3 A;  1UBW A;  4KUX A;  3OYR A;  2Z7H A;  2F9K F;  1VG4 A;  1WL0 A;  3M01 A;  3VJB A;  4JXN A;  3P5R A;  5IK6 A;  3WCG A;  4N9U A;  4RXD A;  5DJV F;  3VJA A;  2ZY1 A;  4RYP A;  3LEE A;  3KB9 A;  4JZX A;  3PYA A;  3WC9 A;  5AYP A;  3S9V A;  5DZ2 A;  4Q23 A;  3MAV A;  3WEH A;  1YYQ A;  5IL3 A;  3TFN A;  3LZ9 A;  1YYS A;  3WEI A;  3WCL A;  2ZCS A;  5JA0 F;  3IBA A;  3LSN A;  3ADZ A;  3ICK A;  4NFJ F;  5DGN F;  3M9U A;  5ER8 A;  3DYH A;  3SDR A;  4LOB A;  4KVW A;  2F94 F;  1YYU A;  1VG6 A;  3N3L F;  2FTZ A;  3P41 A;  4LA6 A;  4PVX F;  5DW7 A;  3CKE A;  4OMH A;  3PKO A;  4P0X A;  5IL8 A;  1WL1 A;  2E8U A;  5IKA A;  2ZCO A;  2I19 A;  5B03 A;  2QIS A;  3B7L A;  3IPI A;  4OKZ A;  2F92 F;  5AHU B;  4LFV F;  4RXE A;  4H5E F;  2DH4 A;  5IMI A;  1WKZ A;  3N5H F;  3P5P A;  1RTR A;  2Q58 A;  2RAH A;  4E1E A;  3KRP A;  4F6X A;  1JFA A;  2PS5 A;  3M00 A;  1V4H A;  2ONH A;  3Q2Z A;  4JZB A;  3TFP A;  1RQI A;  4RXA A;  3WJN A;  5ERN A;  4MC3 A;  4KWD A;  2PS4 A;  1N1Z A;  2E8W A;  4MC8 A;  3N5J F;  5CG5 A;  4NUA A;  5CG6 A;  3KRP B;  2E8T A;  2AZK A;  2AZL A;  3ZOU A;  4OKM A; 
#chains in the Genus database with same CATH topology
 5A0I A;  4N1Z F;  4E9Z A;  2H8O A;  1WMW A;  1YV5 A;  2Z4X A;  3N46 F;  5KSX F;  5B0J A;  3V66 A;  5JV1 F;  3M02 A;  3NPR A;  4JXY A;  2ZCR A;  1YQ7 A;  3KRA B;  4F62 A;  3CC9 A;  4LA5 A;  4OMG A;  4KPD A;  3TC1 A;  4L2X F;  3WEK A;  2P1C A;  2Z4Y A;  4GP2 A;  3LK5 A;  2E8X A;  2Q9Z A;  1KIZ A;  3VJC A;  3LGZ B;  5IK9 A;  5B0K A;  4LIX A;  3WEJ A;  4PVY F;  2OPN A;  1YYT A;  5JV2 F;  3ICN A;  2O1O A;  1KIY A;  4EA2 A;  3VJ9 A;  4DHD A;  5JV0 F;  1WL2 A;  5ERO A;  1N21 A;  5IKH A;  1WL3 A;  4DXJ A;  1UBV A;  4JVJ F;  4KVD A;  4LPH F;  1FPS A;  3ICM A;  2ZCQ A;  4LFE A;  2PS7 A;  3LOM A;  5AFX A;  3EGT A;  1YHK A;  2E94 A;  4DWG A;  4LXW A;  5IMN A;  1YYR A;  3OAB A;  3WCF A;  3NF2 A;  4LTZ A;  3BNY A;  5ILJ A;  2E90 A;  4GA3 A;  2AET A;  3P8L A;  3EFQ A;  3ACW A;  2Z4V A;  1HXA A;  2ONG A;  4KVI A;  3V1V A;  4MC0 A;  5ILZ A;  1VG7 A;  3EZ3 A;  2ZEV A;  4F6V A;  1HX9 A;  3ZCD A;  3ACX A;  4QPF A;  5HN9 A;  2OGD A;  3MZV A;  3N0F A;  3RBM A;  4UMJ A;  3WCM A;  5AEL A;  4LLT A;  5EAS A;  3ZMC A;  5E8H A;  3RYE A;  4DZW A;  2ZEU A;  1ZW5 A;  5B0I A;  3WSA A;  3N6K F;  5ILD A;  2F7M F;  4QXS F;  1PS1 A;  3RMG A;  2E92 A;  5HNA A;  4KQ5 A;  3TS7 A;  5DGS F;  3DYG A;  3OAC A;  3LDW A;  3WCA A;  1YJ4 A;  3VJE A;  3KRC A;  1V4I A;  1RQJ A;  3QQV A;  2E93 A;  3WCB A;  4DWB A;  4LTV A;  5B02 A;  5ERM A;  3WEF A;  1V4J A;  1V4E A;  3WSB A;  3LMD A;  3APZ A;  3CP6 A;  5HN8 A;  3KRO A;  3N3D A;  2F8C F;  4OGU A;  3LVS A;  3OAC B;  3Q1O A;  2Q9Y A;  3M0G A;  4WK5 A;  1WY0 A;  2E95 A;  2E4O A;  3WCD A;  4NKF A;  2Z78 A;  3WCC A;  3WJK A;  3WCI A;  4DEM F;  3SDV A;  3LJI A;  5B01 A;  4P0W A;  1UBY A;  3KRO B;  5JUZ F;  4KKM A;  2Z50 A;  1DI1 A;  5HN7 A;  3BNX A;  4NG6 A;  3DYF A;  1UBX A;  1YHM A;  2PS6 A;  1VG2 A;  4K10 A;  3AQ0 A;  3WE9 A;  4KK2 A;  5ILK A;  2E91 A;  4LZC A;  3WEG A;  3PYB A;  3S4J A;  3N1W F;  4GAX A;  3WCE A;  4LUU A;  5DIQ F;  4HD1 A;  3ICZ A;  4H5D F;  3N49 F;  4NFI F;  2Z52 A;  1VG3 A;  3N45 F;  5B0L A;  5IVG A;  3G4F A;  2E8V A;  4DI5 A;  4NFK F;  3QKC A;  2Q80 A;  1DGP A;  5I1U A;  3AQB B;  5DJR F;  4KVY A;  4H5C F;  1JFG A;  1HM4 A;  2VF6 A;  3AE0 A;  5A0K A;  5H9D A;  3ACY A;  2AZJ A;  1V4K A;  3P8R A;  2PS8 A;  3OAB B;  2F8Z F;  5B00 A;  2OA6 A;  3VJD A;  3TFV A;  5DGM F;  1N22 A;  3ID0 A;  3ASX A;  4FJQ A;  4JYX A;  4P0V A;  4XQR F;  5E8K A;  3UCA A;  3WJO A;  3W7F A;  5IM1 A;  4NKE A;  4RXC A;  3SAE A;  3RYW A;  4LFG A;  5IK0 A;  5B0M A;  5ILI A;  4ZQ8 A;  2FOR A;  3KRF A;  4LPG F;  4XQT F;  1HXC A;  1HM7 A;  5C05 A;  1N23 A;  2Z4W A;  5IN8 A;  3SDQ A;  1YHL A;  4KQS A;  3LLW A;  3SDU A;  1N1B A;  3KBK A;  2F89 F;  2OPM A;  5DHK A;  3Q30 A;  3AQC B;  5A0J A;  1N20 A;  3LG5 A;  4FP4 A;  3KRF B;  5DHI A;  5DJP F;  2J1P A;  4E9U A;  3ZL6 A;  1N24 A;  1HXG A;  4XQS F;  4RNQ A;  5EAT A;  2AEK A;  5E8L A;  5IMP A;  3NPK A;  3SDT A;  3ZMB A;  4KPJ A;  4LZ0 A;  4EA1 A;  3G4D A;  3N1V F;  3PDE A;  3Q2Q A;  4KQU A;  3KRA A;  2Z7I A;  3KRC B;  3VJ8 A;  3N0G A;  5ILH A;  4EA0 A;  4LLS A;  2J5C A;  3V1X A;  2J1O A;  5EAU A;  3LGK A;  3WCH A;  3WCJ A;  2AEL A;  2EWG A;  2Z4Z A;  4GP1 A;  1EZF A;  3PH7 A;  5ILY A;  4KFA A;  3NRI A;  4LZ3 A;  1UBW A;  4KUX A;  3OYR A;  2Z7H A;  2F9K F;  1VG4 A;  1WL0 A;  3M01 A;  3VJB A;  4JXN A;  3P5R A;  5IK6 A;  3WCG A;  4N9U A;  4RXD A;  5DJV F;  3VJA A;  2ZY1 A;  4RYP A;  3LEE A;  3KB9 A;  4JZX A;  3PYA A;  3WC9 A;  5AYP A;  3S9V A;  5DZ2 A;  4Q23 A;  3MAV A;  3WEH A;  1YYQ A;  5IL3 A;  3TFN A;  3LZ9 A;  1YYS A;  3WEI A;  3WCL A;  2ZCS A;  5JA0 F;  3IBA A;  3LSN A;  3ADZ A;  3ICK A;  4NFJ F;  5DGN F;  3M9U A;  5ER8 A;  3DYH A;  3SDR A;  4LOB A;  4KVW A;  2F94 F;  1YYU A;  1VG6 A;  3N3L F;  2FTZ A;  3P41 A;  4LA6 A;  4PVX F;  5DW7 A;  3CKE A;  4OMH A;  3PKO A;  4P0X A;  5IL8 A;  1WL1 A;  2E8U A;  5IKA A;  2ZCO A;  2I19 A;  5B03 A;  2QIS A;  3B7L A;  3IPI A;  4OKZ A;  2F92 F;  5AHU B;  4LFV F;  4RXE A;  4H5E F;  2DH4 A;  5IMI A;  1WKZ A;  3N5H F;  3P5P A;  1RTR A;  2Q58 A;  2RAH A;  4E1E A;  3KRP A;  4F6X A;  1JFA A;  2PS5 A;  3M00 A;  1V4H A;  2ONH A;  3Q2Z A;  4JZB A;  3TFP A;  1RQI A;  4RXA A;  3WJN A;  5ERN A;  4MC3 A;  4KWD A;  2PS4 A;  1N1Z A;  2E8W A;  4MC8 A;  3N5J F;  5CG5 A;  4NUA A;  5CG6 A;  3KRP B;  2E8T A;  2AZK A;  2AZL A;  3ZOU A;  4OKM A; 
#chains in the Genus database with same CATH homology
 5A0I A;  4N1Z F;  4E9Z A;  2H8O A;  1WMW A;  1YV5 A;  2Z4X A;  3N46 F;  5KSX F;  5B0J A;  3V66 A;  5JV1 F;  3M02 A;  3NPR A;  4JXY A;  2ZCR A;  1YQ7 A;  3KRA B;  4F62 A;  3CC9 A;  4LA5 A;  4OMG A;  4KPD A;  3TC1 A;  4L2X F;  3WEK A;  2P1C A;  2Z4Y A;  4GP2 A;  3LK5 A;  2E8X A;  2Q9Z A;  1KIZ A;  3VJC A;  3LGZ B;  5IK9 A;  5B0K A;  4LIX A;  3WEJ A;  4PVY F;  2OPN A;  1YYT A;  5JV2 F;  3ICN A;  2O1O A;  1KIY A;  4EA2 A;  3VJ9 A;  4DHD A;  5JV0 F;  1WL2 A;  5ERO A;  1N21 A;  5IKH A;  1WL3 A;  4DXJ A;  1UBV A;  4JVJ F;  4KVD A;  4LPH F;  1FPS A;  3ICM A;  2ZCQ A;  4LFE A;  2PS7 A;  3LOM A;  5AFX A;  3EGT A;  1YHK A;  2E94 A;  4DWG A;  4LXW A;  5IMN A;  1YYR A;  3OAB A;  3WCF A;  3NF2 A;  4LTZ A;  3BNY A;  5ILJ A;  2E90 A;  4GA3 A;  2AET A;  3P8L A;  3EFQ A;  3ACW A;  2Z4V A;  1HXA A;  2ONG A;  4KVI A;  3V1V A;  4MC0 A;  5ILZ A;  1VG7 A;  3EZ3 A;  2ZEV A;  4F6V A;  1HX9 A;  3ZCD A;  3ACX A;  4QPF A;  5HN9 A;  2OGD A;  3MZV A;  3N0F A;  3RBM A;  4UMJ A;  3WCM A;  5AEL A;  4LLT A;  5EAS A;  3ZMC A;  5E8H A;  3RYE A;  4DZW A;  2ZEU A;  1ZW5 A;  5B0I A;  3WSA A;  3N6K F;  5ILD A;  2F7M F;  4QXS F;  1PS1 A;  3RMG A;  2E92 A;  5HNA A;  4KQ5 A;  3TS7 A;  5DGS F;  3DYG A;  3OAC A;  3LDW A;  3WCA A;  1YJ4 A;  3VJE A;  3KRC A;  1V4I A;  1RQJ A;  3QQV A;  2E93 A;  3WCB A;  4DWB A;  4LTV A;  5B02 A;  5ERM A;  3WEF A;  1V4J A;  1V4E A;  3WSB A;  3LMD A;  3APZ A;  3CP6 A;  5HN8 A;  3KRO A;  3N3D A;  2F8C F;  4OGU A;  3LVS A;  3OAC B;  3Q1O A;  2Q9Y A;  3M0G A;  4WK5 A;  1WY0 A;  2E95 A;  2E4O A;  3WCD A;  4NKF A;  2Z78 A;  3WCC A;  3WJK A;  3WCI A;  4DEM F;  3SDV A;  3LJI A;  5B01 A;  4P0W A;  1UBY A;  3KRO B;  5JUZ F;  4KKM A;  2Z50 A;  1DI1 A;  5HN7 A;  3BNX A;  4NG6 A;  3DYF A;  1UBX A;  1YHM A;  2PS6 A;  1VG2 A;  4K10 A;  3AQ0 A;  3WE9 A;  4KK2 A;  5ILK A;  2E91 A;  4LZC A;  3WEG A;  3PYB A;  3S4J A;  3N1W F;  4GAX A;  3WCE A;  4LUU A;  5DIQ F;  4HD1 A;  3ICZ A;  4H5D F;  3N49 F;  4NFI F;  2Z52 A;  1VG3 A;  3N45 F;  5B0L A;  5IVG A;  3G4F A;  2E8V A;  4DI5 A;  4NFK F;  3QKC A;  2Q80 A;  1DGP A;  5I1U A;  3AQB B;  5DJR F;  4KVY A;  4H5C F;  1JFG A;  1HM4 A;  2VF6 A;  3AE0 A;  5A0K A;  5H9D A;  3ACY A;  2AZJ A;  1V4K A;  3P8R A;  2PS8 A;  3OAB B;  2F8Z F;  5B00 A;  2OA6 A;  3VJD A;  3TFV A;  5DGM F;  1N22 A;  3ID0 A;  3ASX A;  4FJQ A;  4JYX A;  4P0V A;  4XQR F;  5E8K A;  3UCA A;  3WJO A;  3W7F A;  5IM1 A;  4NKE A;  4RXC A;  3SAE A;  3RYW A;  4LFG A;  5IK0 A;  5B0M A;  5ILI A;  4ZQ8 A;  2FOR A;  3KRF A;  4LPG F;  4XQT F;  1HXC A;  1HM7 A;  5C05 A;  1N23 A;  2Z4W A;  5IN8 A;  3SDQ A;  1YHL A;  4KQS A;  3LLW A;  3SDU A;  1N1B A;  3KBK A;  2F89 F;  2OPM A;  5DHK A;  3Q30 A;  3AQC B;  5A0J A;  1N20 A;  3LG5 A;  4FP4 A;  3KRF B;  5DHI A;  5DJP F;  2J1P A;  4E9U A;  3ZL6 A;  1N24 A;  1HXG A;  4XQS F;  4RNQ A;  5EAT A;  2AEK A;  5E8L A;  5IMP A;  3NPK A;  3SDT A;  3ZMB A;  4KPJ A;  4LZ0 A;  4EA1 A;  3G4D A;  3N1V F;  3PDE A;  3Q2Q A;  4KQU A;  3KRA A;  2Z7I A;  3KRC B;  3VJ8 A;  3N0G A;  5ILH A;  4EA0 A;  4LLS A;  2J5C A;  3V1X A;  2J1O A;  5EAU A;  3LGK A;  3WCH A;  3WCJ A;  2AEL A;  2EWG A;  2Z4Z A;  4GP1 A;  1EZF A;  3PH7 A;  5ILY A;  4KFA A;  3NRI A;  4LZ3 A;  1UBW A;  4KUX A;  3OYR A;  2Z7H A;  2F9K F;  1VG4 A;  1WL0 A;  3M01 A;  3VJB A;  4JXN A;  3P5R A;  5IK6 A;  3WCG A;  4N9U A;  4RXD A;  5DJV F;  3VJA A;  2ZY1 A;  4RYP A;  3LEE A;  3KB9 A;  4JZX A;  3PYA A;  3WC9 A;  5AYP A;  3S9V A;  5DZ2 A;  4Q23 A;  3MAV A;  3WEH A;  1YYQ A;  5IL3 A;  3TFN A;  3LZ9 A;  1YYS A;  3WEI A;  3WCL A;  2ZCS A;  5JA0 F;  3IBA A;  3LSN A;  3ADZ A;  3ICK A;  4NFJ F;  5DGN F;  3M9U A;  5ER8 A;  3DYH A;  3SDR A;  4LOB A;  4KVW A;  2F94 F;  1YYU A;  1VG6 A;  3N3L F;  2FTZ A;  3P41 A;  4LA6 A;  4PVX F;  5DW7 A;  3CKE A;  4OMH A;  3PKO A;  4P0X A;  5IL8 A;  1WL1 A;  2E8U A;  5IKA A;  2ZCO A;  2I19 A;  5B03 A;  2QIS A;  3B7L A;  3IPI A;  4OKZ A;  2F92 F;  5AHU B;  4LFV F;  4RXE A;  4H5E F;  2DH4 A;  5IMI A;  1WKZ A;  3N5H F;  3P5P A;  1RTR A;  2Q58 A;  2RAH A;  4E1E A;  3KRP A;  4F6X A;  1JFA A;  2PS5 A;  3M00 A;  1V4H A;  2ONH A;  3Q2Z A;  4JZB A;  3TFP A;  1RQI A;  4RXA A;  3WJN A;  5ERN A;  4MC3 A;  4KWD A;  2PS4 A;  1N1Z A;  2E8W A;  4MC8 A;  3N5J F;  5CG5 A;  4NUA A;  5CG6 A;  3KRP B;  2E8T A;  2AZK A;  2AZL A;  3ZOU A;  4OKM A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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