4FNVA

Crystal structure of heparinase iii
Total Genus 232
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
232
sequence length
659
structure length
659
Chain Sequence
VVDPQVFEAINLNYPGLEKVKEFYEAGEHYYAANALLEYYRTRTNVTNPNLSLINVTISEAEQAKADYALVDYRFHVNNFYEDKETLKPYSVKQDGGINWEYSPKDASDEYQKQLHRHQWFIPQAKAYRVSGDEKYIQSWIEVYKNWIENNPKPTTGPNTTSWWQLQVSTRIGDQVQLLEYFKNSVNFTPEWLSTFLVEFAEQADFLVDYPYESGGNILISQANALATAGTLMPEFKNAEKWMNTGYQILSEEVQNQIMSDGWHKEMSLHYHIGIVADFYEAMKLAEANQLSSKLPSDFTEPLRKAAEVVMYFTYPNYFIKGSDNVVPMFNDSWSRTRNVLKNTNFKQYVEMFPDSEELKYMQTAGNGGTAQGRTPNNDMKLFDQAGYYVLRNGWTPASTVMILSNNKSNDASNSLSAYSHNQPDNGTFELYHNGRNFFPDSGVCTYYTSGGDNDLRYWFRGIDKHNTLSIGKQNIKKAAGKLLKSEEGATELVVFENQGYDNLKHRRAVFYVNKKFFVLVDEGIGNAEGTINLSFNLCEGTASEVVMDTDKNGVHTAFSNNNNIIVRTFANKAVTCSPFTGRIAYLVDGAYNTRQSYTIDMNKSADETARYITVILPVNGSTDTSSISAKFIDSGYSENSASVEVSVNGETHTLSYTL
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structural basis of heparan sulfate-specific degradation by heparinase III.
pubmed doi rcsb
molecule tags Lyase
molecule keywords Heparinase III protein, heparitin sulfate lyase
total genus 232
structure length 659
sequence length 659
ec nomenclature ec 4.2.2.8: Heparin-sulfate lyase.
pdb deposition date 2012-06-20

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF07940 Hepar_II_III Heparinase II/III-like protein
A PF16889 Hepar_II_III_N Heparinase II/III N-terminus
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.50.10.100 Mainly Alpha Alpha/alpha barrel Glycosyltransferase Chondroitin AC/alginate lyase 4fnvA01
2.70.98.70 Mainly Beta Distorted Sandwich Beta-galactosidase; Chain A, domain 5 Beta-galactosidase; Chain A, domain 5 4fnvA02
1N7RA 2E22A 1RW9A 4OK2A 3VSMA 4NEIA 1F1SA 2BRPA 3NFVA 3VSNA 5JMFA 1N7PA 1LOHA 1C82A 1HN0A 1OJPA 4FNVA 4MMIA 4OZWA 4OJZA 1J0NA 4F10A 1LXMA 4MMHA 1RWFA 5JMDA 1HMWA 2Q1FA 1OJOA 3E80A 1X1IA 3NNBA 1HV6A 1OJMA 1OJNA 1QAZA 3AFLA 1RWGA 4E1YA 1J0MA 1N7QA 1RWAA 1RWHA 4F13A 4OZVA 2FUQA 2WCOA 2BRWA 1I8QA 1HMUA 3E7JA 1HM2A 2FUTA 3A0OA 2WDAA 1W3YA 1EGUA 2X03A 1N7OA 1F9GA 1LXKA 1N7NA 1RWCA 1X1JA 2BRVX 2E24A 1X1HA 1HM3A 4OK4A 1CB8A
chains in the Genus database with same CATH superfamily
2OKXA 4M76A 3RX5A 3WKGA 2Y73A 2CFGA 1DL2A 1W6JA 3E73A 3DDFA 3TY1A 3G4FA 1L2AA 5IL3A 4Z4JA 1TN8B 4L9PB 2B4FA 3KN4A 3Q78B 3P5PA 2V8JA 3M75A 3CZJA 1X1IA 2J5CA 2WY8A 5CD2A 4KFFA 1CEMA 1J0MA 1RWAA 3BUIA 4DODA 3E33B 3S4BA 3I3BA 2GOXA 1JYXA 3QT3A 3BVWA 3BVXA 1NSZA 5FO8B 2ALWA 1F9GA 1RWCA 1HX9A 2GZ6A 5ILKA 1US1A 1N23A 3S4DA 5KKBA 1GXOA 2SQCA 4TF4A 1DYUA 3M7EA 4OK2A 1JZ4A 3D51A 1NSSA 3HXBB 1K1WA 1IQYA 4FNVA 2F0YB 4CJ0A 3H3KA 3X17A 1PS3A 1UT9A 2F18A 1OJNA 2CWVA 1RWGA 4YDOB 3DYMA 2DRSA 4KKIA 4D94A 1SIHA 1MMUA 1QSJA 2GH4A 1V5DA 1KRFA 4Z4LA 2P0VA 3DPYB 3VDCA 2JKPA 2WOHA 1LF6A 1A2VA 2V3PA 3EU8A 1JRQA 2CIRA 2F7PA 3ANKA 3IAPA 3CU7A 2RDYA 1GXNA 3EJPA 4FUSA 4ZH1A 1DOGA 3MUY1 1WU4A 2ZBLA 1JZ7A 3E34B 2YIKA 1WMNA 2AFAA 4OJZA 1L7KA 4YCRA 3D4ZA 1MMZA 1XWQA 1N4RB 3E6UA 1H3CA 3H2WA 5E2JA 5GW7A 1NI1B 3SDTA 5ILYA 2AHFA 1NSXA 2WVYA 3N0FA 2CQTA 3X41A 1S63B 2EACA 3D4YA 3WIQA 5A1AA 1G87A 3Q7FB 3Q1NA 5JPNB 3DX0A 4GTRB 3GT5A 3SQCA 4L6XA 1KWFA 1Z45A 2XN0A 5FO9B 1IVWA 1TQWA 3BUPA 3WVFA 3SFYB 5DGQA 4BTWA 3MWXA 3DDGA 3OBAA 2WW2A 2A73B 3DYPA 2BRPA 3LZ9A 1O6RA 2C10A 1LOHA 2CISA 4MMIA 1NSRA 4F10A 1FBWA 1LD8B 3M7CA 3VDAA 1AYXA 1OJOA 5ILJA 1TQUA 1GHQA 2FBAA 3PZ1B 4GTVB 2WO0A 4GL3A 3MUZ1 1N7QA 1N95B 2FUQA 3SDQA 3BLCA 3DCDA 4GTMB 3EQAA 2WDAA 3ANJA 3PYAA 4LNGB 4LIXA 1O6QA 1AVLA 1EKMA 2FYVA 1JYVA 2JF4A 3D5RA 5MEHA 4DUVA 1QBQB 2I07B 3PGBA 2CFLA 4WVBA 1SIIA 2PN5A 1IA6A 3M76A 2WYNA 4OZWA 1NS8A 3M00A 4AYPA 3QFZA 1J0NA 3S4AA 4AYQA 2XHNA 3NBBA 1N9EA 2OOVC 2XWJB 1H13A 4WVCA 3K25A 2JKEA 3OEDA 3VD4A 2WOFA 3MPHA 1H39A 2OQEC 1N94B 3CIHA 4BOJA 2ONGA 3DX1A 1W3YA 3DSTB 1K72A 1N7NA 3PZ3B 2FUZA 3H7LA 1TQVA 1JS4A 2BT3A 5IKAA 2HTBA 3ALAA 3DSXB 3MV01 2E22A 3EUVB 3RENA 2OOVA 4UFCA 3LVTA 1KKTA 3VD5A 1GAHA 3A24A 4KTPA 1SA4B 2OQEA 3T0BA 4MMHA 1O6HA 2F7OA 2EADA 3E80A 2YFOA 3LOYA 1F9DA 3T2OA 3D3IA 3X3YA 1F4AA 1HXGA 3T0UA 1KSIA 1G9GA 1KSCA 1FT2B 3C72B 1C3DA 1TNOB 2FV1A 3M01A 2D73A 2ZZRA 5M7YA 1HM2A 3M73A 3QSPA 3X40A 2QNOA 4Q2BA 3E32B 2Y74A 1AGMA 3WKFA 1H35A 3P2CA 4D4DA 1L7JA 3AFJA 3GLYA 3BUBA 5KBPA 3G4DA 5IK9A 3P5RA 2E2TA 3DYOA 3VSMA 3OXUA 3RSYA 1IVVA 3NFVA 5JMFA 4FNSA 3SXXA 2BB6A 2B39A 3ACTA 1H36A 2XFGA 2WVXA 2DRRA 4ZH5A 2NOJA 5JMDA 3M78A 1O79A 3WKIA 3G6JB 2ZL8A 4BZGA 2D1WA 3HXDB 3SDRA 1N20A 2G02A 3WFAA 1H14A 1TN7B 1V7VA 4ZRQA 1LTXB 1D6YA 3SEPA 1GSZA 3BGAA 3OB8A 1JCQB 5EATA 2FV0A 3EJSA 2CG0A 3K11A 1MN0A 3VD7A 4V1RA 4L0GA 1KSDA 2Z07A 4BOKA 3QFYA 1NS2A 1D8DB 1HXCA 1NSMA 4KFEA 1PX4A 1X1HA 4AYRA 3BVTA 4V1SA 1V7WA 1O7DD 2F7RA 1O5MB 1NSVA 3T09A 3VD9A 4NEIA 4KFDA 1C82A 1FMIA 4J5TA 1JZ8A 4TTGA 2D5JA 4CJ1A 1TQTA 4CE7A 1SA5B 3M77A 4GTQB 3RX8A 4Q88A 2H6FB 3OS7A 1KREA 1JOVA 3VXDA 4WU0A 1LURA 4EHMB 3RX7A 1TN6B 2WCOA 1N4PB 1UG9A 1CLCA 1W6GA 3HI7A 2WGQA 1LVNA 1RQ5A 1NS4A 1RKYA 3QT9A 1FBOA 3IMHA 3QRYA 1OACA 3M72A 1TU5A 4BZEA 1HM3A 1GAIA 2BB5A 3S9VA 1R33A 2OW7A 1RW9A 3EJQA 3I3DA 3VSNA 3W5MA 5ILHA 1VD5A 3DX3A 2EABA 1FO3A 2OW6A 1KZOB 1LD7B 3T2PA 1HZFA 1QAKA 2BBCA 3T0AA 2JJBA 4E1YA 1N4SB 2WW1A 3SDUA 3QWTA 4BZFA 3HIGA 1N21A 3BUQA 4TXTA 2CWTA 1JCRB 2E2VA 3VD3A 2CFKA 2WIIB 3DX2A 4EL8A 2E2UA 2DROA 1W7CA 1X1JA 2XQWA 2C11A 2XN1A 1JYNA 3BVUA 1SQCA 1AVKA 1H37A 1S64B 3M71A 2YX9A 1NC5A 1W6KA 1DCEB 2IEJB 2WVZA 3W7UA 1HN0A 3Q79B 4QT9A 3NJXA 2F6DA 4LNBB 4FXGB 1L1YA 3SX1A 1GXMA 1HMWA 3EJUA 3HIIA 3IAQA 1FO2A 1FT1B 3CV5A 3Q75B 1O1TB 4MU9A 1JZ5A 1QQFA 5C05A 1W4NA 1W5ZA 1N1BA 4D4CA 1I8QA 4DOEA 3NBJA 5CA3A 1FPPB 1H3BA 3QXFA 3I3EA 3D50A 3KIIA 5ILDA 5FOBB 2XSGA 3M02A 1R76A 5IK0A 1HN1A 3QDEA 4GAXA 2ZIRB 5IL8A 1JZ6A 3PMMA 1ULVA 3TF4A 4ZRPA 2PMVA 3M74A 3BUDA 3T08A 2RI8A 4KTRA 3SAEA 2YFNA 2WVXB 2ZQ0A 3D5SA 1W6CA 2CQSA 3W7SA 1QAZA 3HXCB 2NVPA 2JKAA 3HXEB 4GTTB 3RJ3A 3WKHA 2BEDB 3EJRA 2ONHA 1NS0A 1N22A 4KKJA 3DECA 1N4QB 1KFGA 2BRVX 1LXKA 3DSVB 2E24A 2XN2A 3AMOA 1UI8A 3EJTA 4K3AA 3KLSA 1RJOA 1FCEA 1H12A 3CZSA 1YGAA 1H3AA 1QWUA 2V8IA 2A8ZA 1HWWA 4XUVA 2CFDA 3ON6A 1UI7A 3VDBA 2CG1A 3WIRA 3Q7AB 1D8EB 4FNRA 1G6IA 1V5CA 1JCSB 1XWTA 3K7XA 5IM1A 3NNBA 1TQSA 1G9JA 1TNZB 3E37B 3WUXA 1SPUA 2WW0A 1RWHA 5GZKA 5GY3A 1NKGA 1NXCA 3S4CA 3WC3A 2H6GB 3ECQA 3VW5A 1N1ZA 1NS7A 1HXKA 1LF9A 1IS9A 2X03A 4D4BA 3W7XA 4EV5A 3WIWA 3NREA 4D4AA 5AGDA 5DHKA 1WU6A 4FJQA 2CIQA 1N7RA 5M7IA 3DSWB 3PZ4B 1SNZA 2HTAA 1PU4A 3QPFA 2VN4A 3D52A 4AQ0A 2WYHA 4YDEB 1AV4A 1D6ZA 3K5TA 3HXFB 1QX1A 2V3NA 4C1SA 3E1F1 1OJMA 1WU5A 4BTXA 2WINB 1IA7A 1N24A 3W7TA 4F13A 1QALA 3BLBA 2WZSA 1X9DA 1HMUA 2VN7A 4JJJA 3N9HA 3E7JA 1WMPA 5E1QA 3A0OA 4MBGB 2EAEA 1N7OA 4K35A 1TXKA 2CWUA 5DHIA 5DGRA 3X3ZA 4OK4A 1IVXA 4GTPB 1DP0A 1MMYA 2WYIA 1WZZA 3N0GA 3BS6A 3X42A 3PYBA 4DUXA 1NSUA 3DRAB 3W5NA 3Q73B 1N9AB 1N7PA 1NL4B 1IU7A 1O1SB 1UMPA 3W7WA 2DRQA 4ONTA 3RRSA 1TF4A 2Q1FA 4DI5A 2F7QA 2F1BA 1HV6A 2RI9A 2PNCA 1YQ2A 2JG0A 4OZVA 2ZISB 1F9OA 3QG0A 3NJVA 2R2LB 3QXQA 4GTSB 3KSQB 5EAUA 1HTYA 1IVUA 2FUTA 4GTOB 3DSUB 1XW2A 1TNUB 1FAEA 4RNQA 1H54A 3WA3A 3BVVA 4LNVA 4FNPA 4AYOA 2RGKA 1K1XA 3KQ4A 1TNYB 1QWNA 1KS8A 1QAFA 1F1SA 3EZ8A 1F4HA 1OJPA 2V8KA 3EU5B 3T0DA 1R34A 1LXMA 1RWFA 2XWBB 4RNLA 3X3XA 1PX3A 1D6UA 4BZHA 3A3VA 4ZG8A 3SFXB 4FNTA 3AFLA 1GA2A 2CFWA 2H6HB 2AHGA 1MZCB 5IKHA 4BTYA 3GZKA 1JYWA 2BRWA 1JZ3A 1X81B 2W0QA 1HCUA 3T33A 5EASA 2H6IB 1FP3A 1IQXA 1V7XA 2G0DA 3ACSA 3SDVA 1KZPB 4DUWA 1CB8A 5ILIA 3KSLB 3WA2X 5IK6A 3AMOB 3DSSB 4EV2A 1JZ2A 2F1AA 1K1YA 1MMXA 3DX4A 4WVAA 1SO0A 4FXKB 2WY7A 1GLMA 5JPMB 1TNBB 3MI6A 3T2QA 3M7LA 3E30B 3PZ2B 4FNUA 5CZLA 1W2ZA 1HXAA 1O1RB 2WW3A 5ILZA 5FO7B 3CZNA 3ANIA 3J7HA 1EGUA 2ZXQA 3M7BA 3MV11 4FNQA 1WMOA 2D8LA
chains in the Genus database with same CATH topology
4DUVA 1N7RA 1RW9A 1SNZA 3I3DA 2HTAA 3VSNA 4OZWA 1NS8A 3TY1A 1J0NA 4AQ0A 3T2PA 3CZJA 1X1IA 2XHNA 3T0AA 3E1F1 1OJMA 4E1YA 2WW1A 1J0MA 3K25A 1RWAA 4F13A 2JKEA 4BZFA 2WZSA 3VD4A 1HMUA 1JYXA 3I3BA 3VD3A 3E7JA 5E1QA 3A0OA 1W3YA 1NSZA 1N7OA 1F9GA 1RWCA 1N7NA 1X1JA 1TXKA 4OK4A 1JYNA 1DP0A 1MMYA 2HTBA 3BS6A 3MV01 2E22A 4DUXA 4OK2A 1NSUA 1JZ4A 3VD5A 1NSSA 2WVZA 1K1WA 3A24A 1N7PA 1HN0A 4FNVA 3NJXA 3T0BA 4MMHA 1HMWA 3IAQA 2Q1FA 3E80A 3T2OA 1JZ5A 1HV6A 1OJNA 1F4AA 1RWGA 3DYMA 1YQ2A 4OZVA 1MMUA 3NJVA 1I8QA 2D73A 3VDCA 3I3EA 1HM2A 2FUTA 2JKPA 1LF6A 2XSGA 1HN1A 2CIRA 3IAPA 1L7JA 3MUY1 1JZ6A 1K1XA 1JZ7A 1ULVA 3DYOA 3VSMA 1F1SA 3NFVA 5JMFA 4OJZA 1F4HA 1OJPA 1L7KA 2WVXA 3T0DA 1MMZA 1LXMA 1RWFA 5JMDA 4RNLA 3T08A 1PX3A 4BZHA 4BZGA 2WVYA 2WVXB 1NSXA 2ZQ0A 3WFAA 1QAZA 3AFLA 5A1AA 3Q1NA 3SEPA 3BGAA 3OB8A 2JKAA 2BRWA 1JZ3A 1JYWA 1MN0A 3VD7A 1Z45A 1NS0A 3DECA 1NSMA 1NS2A 2BRVX 1LXKA 3WVFA 2E24A 1PX4A 1X1HA 4DUWA 1CB8A 3MWXA 3OBAA 2WW2A 1YGAA 1NSVA 3T09A 3VD9A 4NEIA 3DYPA 2BRPA 1LOHA 1C82A 2CISA 4J5TA 4MMIA 1JZ2A 1JZ8A 1NSRA 1K1YA 4F10A 1MMXA 3VDBA 4TTGA 1SO0A 3VDAA 1OJOA 3OS7A 3T2QA 3NNBA 1JOVA 2WW0A 1LURA 3MUZ1 1N7QA 1RWHA 2FUQA 1NKGA 2WCOA 1UG9A 3BLCA 3DCDA 2WW3A 3ECQA 1NS7A 1NS4A 3J7HA 2WDAA 1LF9A 1EGUA 2X03A 2ZXQA 3IMHA 1JYVA 3MV11 3NREA 4BZEA 1HM3A 2CIQA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1N7R A;  2E22 A;  1RW9 A;  4OK2 A;  3VSM A;  4NEI A;  1F1S A;  2BRP A;  3NFV A;  3VSN A;  5JMF A;  1N7P A;  1LOH A;  1C82 A;  1HN0 A;  1OJP A;  4FNV A;  4MMI A;  4OZW A;  4OJZ A;  1J0N A;  4F10 A;  1LXM A;  4MMH A;  1RWF A;  5JMD A;  1HMW A;  2Q1F A;  1OJO A;  3E80 A;  1X1I A;  3NNB A;  1HV6 A;  1OJM A;  1OJN A;  1QAZ A;  3AFL A;  1RWG A;  4E1Y A;  1J0M A;  1N7Q A;  1RWA A;  1RWH A;  4F13 A;  4OZV A;  2FUQ A;  2WCO A;  2BRW A;  1I8Q A;  1HMU A;  3E7J A;  1HM2 A;  2FUT A;  3A0O A;  2WDA A;  1W3Y A;  1EGU A;  2X03 A;  1N7O A;  1F9G A;  1LXK A;  1N7N A;  1RWC A;  1X1J A;  2BRV X;  2E24 A;  1X1H A;  1HM3 A;  4OK4 A;  1CB8 A; 
#chains in the Genus database with same CATH topology
 2OKX A;  4M76 A;  3RX5 A;  3WKG A;  2Y73 A;  2CFG A;  1DL2 A;  1W6J A;  3E73 A;  3DDF A;  3TY1 A;  3G4F A;  1L2A A;  5IL3 A;  4Z4J A;  1TN8 B;  4L9P B;  2B4F A;  3KN4 A;  3Q78 B;  3P5P A;  2V8J A;  3M75 A;  3CZJ A;  1X1I A;  2J5C A;  2WY8 A;  5CD2 A;  4KFF A;  1CEM A;  1J0M A;  1RWA A;  3BUI A;  4DOD A;  3E33 B;  3S4B A;  3I3B A;  2GOX A;  1JYX A;  3QT3 A;  3BVW A;  3BVX A;  1NSZ A;  5FO8 B;  2ALW A;  1F9G A;  1RWC A;  1HX9 A;  2GZ6 A;  5ILK A;  1US1 A;  1N23 A;  3S4D A;  5KKB A;  1GXO A;  2SQC A;  4TF4 A;  1DYU A;  3M7E A;  4OK2 A;  1JZ4 A;  3D51 A;  1NSS A;  3HXB B;  1K1W A;  1IQY A;  4FNV A;  2F0Y B;  4CJ0 A;  3H3K A;  3X17 A;  1PS3 A;  1UT9 A;  2F18 A;  1OJN A;  2CWV A;  1RWG A;  4YDO B;  3DYM A;  2DRS A;  4KKI A;  4D94 A;  1SIH A;  1MMU A;  1QSJ A;  2GH4 A;  1V5D A;  1KRF A;  4Z4L A;  2P0V A;  3DPY B;  3VDC A;  2JKP A;  2WOH A;  1LF6 A;  1A2V A;  2V3P A;  3EU8 A;  1JRQ A;  2CIR A;  2F7P A;  3ANK A;  3IAP A;  3CU7 A;  2RDY A;  1GXN A;  3EJP A;  4FUS A;  4ZH1 A;  1DOG A;  3MUY 1;  1WU4 A;  2ZBL A;  1JZ7 A;  3E34 B;  2YIK A;  1WMN A;  2AFA A;  4OJZ A;  1L7K A;  4YCR A;  3D4Z A;  1MMZ A;  1XWQ A;  1N4R B;  3E6U A;  1H3C A;  3H2W A;  5E2J A;  5GW7 A;  1NI1 B;  3SDT A;  5ILY A;  2AHF A;  1NSX A;  2WVY A;  3N0F A;  2CQT A;  3X41 A;  1S63 B;  2EAC A;  3D4Y A;  3WIQ A;  5A1A A;  1G87 A;  3Q7F B;  3Q1N A;  5JPN B;  3DX0 A;  4GTR B;  3GT5 A;  3SQC A;  4L6X A;  1KWF A;  1Z45 A;  2XN0 A;  5FO9 B;  1IVW A;  1TQW A;  3BUP A;  3WVF A;  3SFY B;  5DGQ A;  4BTW A;  3MWX A;  3DDG A;  3OBA A;  2WW2 A;  2A73 B;  3DYP A;  2BRP A;  3LZ9 A;  1O6R A;  2C10 A;  1LOH A;  2CIS A;  4MMI A;  1NSR A;  4F10 A;  1FBW A;  1LD8 B;  3M7C A;  3VDA A;  1AYX A;  1OJO A;  5ILJ A;  1TQU A;  1GHQ A;  2FBA A;  3PZ1 B;  4GTV B;  2WO0 A;  4GL3 A;  3MUZ 1;  1N7Q A;  1N95 B;  2FUQ A;  3SDQ A;  3BLC A;  3DCD A;  4GTM B;  3EQA A;  2WDA A;  3ANJ A;  3PYA A;  4LNG B;  4LIX A;  1O6Q A;  1AVL A;  1EKM A;  2FYV A;  1JYV A;  2JF4 A;  3D5R A;  5MEH A;  4DUV A;  1QBQ B;  2I07 B;  3PGB A;  2CFL A;  4WVB A;  1SII A;  2PN5 A;  1IA6 A;  3M76 A;  2WYN A;  4OZW A;  1NS8 A;  3M00 A;  4AYP A;  3QFZ A;  1J0N A;  3S4A A;  4AYQ A;  2XHN A;  3NBB A;  1N9E A;  2OOV C;  2XWJ B;  1H13 A;  4WVC A;  3K25 A;  2JKE A;  3OED A;  3VD4 A;  2WOF A;  3MPH A;  1H39 A;  2OQE C;  1N94 B;  3CIH A;  4BOJ A;  2ONG A;  3DX1 A;  1W3Y A;  3DST B;  1K72 A;  1N7N A;  3PZ3 B;  2FUZ A;  3H7L A;  1TQV A;  1JS4 A;  2BT3 A;  5IKA A;  2HTB A;  3ALA A;  3DSX B;  3MV0 1;  2E22 A;  3EUV B;  3REN A;  2OOV A;  4UFC A;  3LVT A;  1KKT A;  3VD5 A;  1GAH A;  3A24 A;  4KTP A;  1SA4 B;  2OQE A;  3T0B A;  4MMH A;  1O6H A;  2F7O A;  2EAD A;  3E80 A;  2YFO A;  3LOY A;  1F9D A;  3T2O A;  3D3I A;  3X3Y A;  1F4A A;  1HXG A;  3T0U A;  1KSI A;  1G9G A;  1KSC A;  1FT2 B;  3C72 B;  1C3D A;  1TNO B;  2FV1 A;  3M01 A;  2D73 A;  2ZZR A;  5M7Y A;  1HM2 A;  3M73 A;  3QSP A;  3X40 A;  2QNO A;  4Q2B A;  3E32 B;  2Y74 A;  1AGM A;  3WKF A;  1H35 A;  3P2C A;  4D4D A;  1L7J A;  3AFJ A;  3GLY A;  3BUB A;  5KBP A;  3G4D A;  5IK9 A;  3P5R A;  2E2T A;  3DYO A;  3VSM A;  3OXU A;  3RSY A;  1IVV A;  3NFV A;  5JMF A;  4FNS A;  3SXX A;  2BB6 A;  2B39 A;  3ACT A;  1H36 A;  2XFG A;  2WVX A;  2DRR A;  4ZH5 A;  2NOJ A;  5JMD A;  3M78 A;  1O79 A;  3WKI A;  3G6J B;  2ZL8 A;  4BZG A;  2D1W A;  3HXD B;  3SDR A;  1N20 A;  2G02 A;  3WFA A;  1H14 A;  1TN7 B;  1V7V A;  4ZRQ A;  1LTX B;  1D6Y A;  3SEP A;  1GSZ A;  3BGA A;  3OB8 A;  1JCQ B;  5EAT A;  2FV0 A;  3EJS A;  2CG0 A;  3K11 A;  1MN0 A;  3VD7 A;  4V1R A;  4L0G A;  1KSD A;  2Z07 A;  4BOK A;  3QFY A;  1NS2 A;  1D8D B;  1HXC A;  1NSM A;  4KFE A;  1PX4 A;  1X1H A;  4AYR A;  3BVT A;  4V1S A;  1V7W A;  1O7D D;  2F7R A;  1O5M B;  1NSV A;  3T09 A;  3VD9 A;  4NEI A;  4KFD A;  1C82 A;  1FMI A;  4J5T A;  1JZ8 A;  4TTG A;  2D5J A;  4CJ1 A;  1TQT A;  4CE7 A;  1SA5 B;  3M77 A;  4GTQ B;  3RX8 A;  4Q88 A;  2H6F B;  3OS7 A;  1KRE A;  1JOV A;  3VXD A;  4WU0 A;  1LUR A;  4EHM B;  3RX7 A;  1TN6 B;  2WCO A;  1N4P B;  1UG9 A;  1CLC A;  1W6G A;  3HI7 A;  2WGQ A;  1LVN A;  1RQ5 A;  1NS4 A;  1RKY A;  3QT9 A;  1FBO A;  3IMH A;  3QRY A;  1OAC A;  3M72 A;  1TU5 A;  4BZE A;  1HM3 A;  1GAI A;  2BB5 A;  3S9V A;  1R33 A;  2OW7 A;  1RW9 A;  3EJQ A;  3I3D A;  3VSN A;  3W5M A;  5ILH A;  1VD5 A;  3DX3 A;  2EAB A;  1FO3 A;  2OW6 A;  1KZO B;  1LD7 B;  3T2P A;  1HZF A;  1QAK A;  2BBC A;  3T0A A;  2JJB A;  4E1Y A;  1N4S B;  2WW1 A;  3SDU A;  3QWT A;  4BZF A;  3HIG A;  1N21 A;  3BUQ A;  4TXT A;  2CWT A;  1JCR B;  2E2V A;  3VD3 A;  2CFK A;  2WII B;  3DX2 A;  4EL8 A;  2E2U A;  2DRO A;  1W7C A;  1X1J A;  2XQW A;  2C11 A;  2XN1 A;  1JYN A;  3BVU A;  1SQC A;  1AVK A;  1H37 A;  1S64 B;  3M71 A;  2YX9 A;  1NC5 A;  1W6K A;  1DCE B;  2IEJ B;  2WVZ A;  3W7U A;  1HN0 A;  3Q79 B;  4QT9 A;  3NJX A;  2F6D A;  4LNB B;  4FXG B;  1L1Y A;  3SX1 A;  1GXM A;  1HMW A;  3EJU A;  3HII A;  3IAQ A;  1FO2 A;  1FT1 B;  3CV5 A;  3Q75 B;  1O1T B;  4MU9 A;  1JZ5 A;  1QQF A;  5C05 A;  1W4N A;  1W5Z A;  1N1B A;  4D4C A;  1I8Q A;  4DOE A;  3NBJ A;  5CA3 A;  1FPP B;  1H3B A;  3QXF A;  3I3E A;  3D50 A;  3KII A;  5ILD A;  5FOB B;  2XSG A;  3M02 A;  1R76 A;  5IK0 A;  1HN1 A;  3QDE A;  4GAX A;  2ZIR B;  5IL8 A;  1JZ6 A;  3PMM A;  1ULV A;  3TF4 A;  4ZRP A;  2PMV A;  3M74 A;  3BUD A;  3T08 A;  2RI8 A;  4KTR A;  3SAE A;  2YFN A;  2WVX B;  2ZQ0 A;  3D5S A;  1W6C A;  2CQS A;  3W7S A;  1QAZ A;  3HXC B;  2NVP A;  2JKA A;  3HXE B;  4GTT B;  3RJ3 A;  3WKH A;  2BED B;  3EJR A;  2ONH A;  1NS0 A;  1N22 A;  4KKJ A;  3DEC A;  1N4Q B;  1KFG A;  2BRV X;  1LXK A;  3DSV B;  2E24 A;  2XN2 A;  3AMO A;  1UI8 A;  3EJT A;  4K3A A;  3KLS A;  1RJO A;  1FCE A;  1H12 A;  3CZS A;  1YGA A;  1H3A A;  1QWU A;  2V8I A;  2A8Z A;  1HWW A;  4XUV A;  2CFD A;  3ON6 A;  1UI7 A;  3VDB A;  2CG1 A;  3WIR A;  3Q7A B;  1D8E B;  4FNR A;  1G6I A;  1V5C A;  1JCS B;  1XWT A;  3K7X A;  5IM1 A;  3NNB A;  1TQS A;  1G9J A;  1TNZ B;  3E37 B;  3WUX A;  1SPU A;  2WW0 A;  1RWH A;  5GZK A;  5GY3 A;  1NKG A;  1NXC A;  3S4C A;  3WC3 A;  2H6G B;  3ECQ A;  3VW5 A;  1N1Z A;  1NS7 A;  1HXK A;  1LF9 A;  1IS9 A;  2X03 A;  4D4B A;  3W7X A;  4EV5 A;  3WIW A;  3NRE A;  4D4A A;  5AGD A;  5DHK A;  1WU6 A;  4FJQ A;  2CIQ A;  1N7R A;  5M7I A;  3DSW B;  3PZ4 B;  1SNZ A;  2HTA A;  1PU4 A;  3QPF A;  2VN4 A;  3D52 A;  4AQ0 A;  2WYH A;  4YDE B;  1AV4 A;  1D6Z A;  3K5T A;  3HXF B;  1QX1 A;  2V3N A;  4C1S A;  3E1F 1;  1OJM A;  1WU5 A;  4BTX A;  2WIN B;  1IA7 A;  1N24 A;  3W7T A;  4F13 A;  1QAL A;  3BLB A;  2WZS A;  1X9D A;  1HMU A;  2VN7 A;  4JJJ A;  3N9H A;  3E7J A;  1WMP A;  5E1Q A;  3A0O A;  4MBG B;  2EAE A;  1N7O A;  4K35 A;  1TXK A;  2CWU A;  5DHI A;  5DGR A;  3X3Z A;  4OK4 A;  1IVX A;  4GTP B;  1DP0 A;  1MMY A;  2WYI A;  1WZZ A;  3N0G A;  3BS6 A;  3X42 A;  3PYB A;  4DUX A;  1NSU A;  3DRA B;  3W5N A;  3Q73 B;  1N9A B;  1N7P A;  1NL4 B;  1IU7 A;  1O1S B;  1UMP A;  3W7W A;  2DRQ A;  4ONT A;  3RRS A;  1TF4 A;  2Q1F A;  4DI5 A;  2F7Q A;  2F1B A;  1HV6 A;  2RI9 A;  2PNC A;  1YQ2 A;  2JG0 A;  4OZV A;  2ZIS B;  1F9O A;  3QG0 A;  3NJV A;  2R2L B;  3QXQ A;  4GTS B;  3KSQ B;  5EAU A;  1HTY A;  1IVU A;  2FUT A;  4GTO B;  3DSU B;  1XW2 A;  1TNU B;  1FAE A;  4RNQ A;  1H54 A;  3WA3 A;  3BVV A;  4LNV A;  4FNP A;  4AYO A;  2RGK A;  1K1X A;  3KQ4 A;  1TNY B;  1QWN A;  1KS8 A;  1QAF A;  1F1S A;  3EZ8 A;  1F4H A;  1OJP A;  2V8K A;  3EU5 B;  3T0D A;  1R34 A;  1LXM A;  1RWF A;  2XWB B;  4RNL A;  3X3X A;  1PX3 A;  1D6U A;  4BZH A;  3A3V A;  4ZG8 A;  3SFX B;  4FNT A;  3AFL A;  1GA2 A;  2CFW A;  2H6H B;  2AHG A;  1MZC B;  5IKH A;  4BTY A;  3GZK A;  1JYW A;  2BRW A;  1JZ3 A;  1X81 B;  2W0Q A;  1HCU A;  3T33 A;  5EAS A;  2H6I B;  1FP3 A;  1IQX A;  1V7X A;  2G0D A;  3ACS A;  3SDV A;  1KZP B;  4DUW A;  1CB8 A;  5ILI A;  3KSL B;  3WA2 X;  5IK6 A;  3AMO B;  3DSS B;  4EV2 A;  1JZ2 A;  2F1A A;  1K1Y A;  1MMX A;  3DX4 A;  4WVA A;  1SO0 A;  4FXK B;  2WY7 A;  1GLM A;  5JPM B;  1TNB B;  3MI6 A;  3T2Q A;  3M7L A;  3E30 B;  3PZ2 B;  4FNU A;  5CZL A;  1W2Z A;  1HXA A;  1O1R B;  2WW3 A;  5ILZ A;  5FO7 B;  3CZN A;  3ANI A;  3J7H A;  1EGU A;  2ZXQ A;  3M7B A;  3MV1 1;  4FNQ A;  1WMO A;  2D8L A; 
#chains in the Genus database with same CATH homology
 4DUV A;  1N7R A;  1RW9 A;  1SNZ A;  3I3D A;  2HTA A;  3VSN A;  4OZW A;  1NS8 A;  3TY1 A;  1J0N A;  4AQ0 A;  3T2P A;  3CZJ A;  1X1I A;  2XHN A;  3T0A A;  3E1F 1;  1OJM A;  4E1Y A;  2WW1 A;  1J0M A;  3K25 A;  1RWA A;  4F13 A;  2JKE A;  4BZF A;  2WZS A;  3VD4 A;  1HMU A;  1JYX A;  3I3B A;  3VD3 A;  3E7J A;  5E1Q A;  3A0O A;  1W3Y A;  1NSZ A;  1N7O A;  1F9G A;  1RWC A;  1N7N A;  1X1J A;  1TXK A;  4OK4 A;  1JYN A;  1DP0 A;  1MMY A;  2HTB A;  3BS6 A;  3MV0 1;  2E22 A;  4DUX A;  4OK2 A;  1NSU A;  1JZ4 A;  3VD5 A;  1NSS A;  2WVZ A;  1K1W A;  3A24 A;  1N7P A;  1HN0 A;  4FNV A;  3NJX A;  3T0B A;  4MMH A;  1HMW A;  3IAQ A;  2Q1F A;  3E80 A;  3T2O A;  1JZ5 A;  1HV6 A;  1OJN A;  1F4A A;  1RWG A;  3DYM A;  1YQ2 A;  4OZV A;  1MMU A;  3NJV A;  1I8Q A;  2D73 A;  3VDC A;  3I3E A;  1HM2 A;  2FUT A;  2JKP A;  1LF6 A;  2XSG A;  1HN1 A;  2CIR A;  3IAP A;  1L7J A;  3MUY 1;  1JZ6 A;  1K1X A;  1JZ7 A;  1ULV A;  3DYO A;  3VSM A;  1F1S A;  3NFV A;  5JMF A;  4OJZ A;  1F4H A;  1OJP A;  1L7K A;  2WVX A;  3T0D A;  1MMZ A;  1LXM A;  1RWF A;  5JMD A;  4RNL A;  3T08 A;  1PX3 A;  4BZH A;  4BZG A;  2WVY A;  2WVX B;  1NSX A;  2ZQ0 A;  3WFA A;  1QAZ A;  3AFL A;  5A1A A;  3Q1N A;  3SEP A;  3BGA A;  3OB8 A;  2JKA A;  2BRW A;  1JZ3 A;  1JYW A;  1MN0 A;  3VD7 A;  1Z45 A;  1NS0 A;  3DEC A;  1NSM A;  1NS2 A;  2BRV X;  1LXK A;  3WVF A;  2E24 A;  1PX4 A;  1X1H A;  4DUW A;  1CB8 A;  3MWX A;  3OBA A;  2WW2 A;  1YGA A;  1NSV A;  3T09 A;  3VD9 A;  4NEI A;  3DYP A;  2BRP A;  1LOH A;  1C82 A;  2CIS A;  4J5T A;  4MMI A;  1JZ2 A;  1JZ8 A;  1NSR A;  1K1Y A;  4F10 A;  1MMX A;  3VDB A;  4TTG A;  1SO0 A;  3VDA A;  1OJO A;  3OS7 A;  3T2Q A;  3NNB A;  1JOV A;  2WW0 A;  1LUR A;  3MUZ 1;  1N7Q A;  1RWH A;  2FUQ A;  1NKG A;  2WCO A;  1UG9 A;  3BLC A;  3DCD A;  2WW3 A;  3ECQ A;  1NS7 A;  1NS4 A;  3J7H A;  2WDA A;  1LF9 A;  1EGU A;  2X03 A;  2ZXQ A;  3IMH A;  1JYV A;  3MV1 1;  3NRE A;  4BZE A;  1HM3 A;  2CIQ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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