1FZHE

Methane monooxygenase hydroxylase, form ii pressurized with xenon gas
Total Genus 61
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
61
sequence length
165
structure length
165
Chain Sequence
KLGIHSNDTRDAWVNKIAQLNTLEKAAEMLKQFRMDHTTPFRNSYELDNDYLWIEAKLEEKVAVLKARAFNEVDFRHKTAFGEDAKSVLDGTVAKMNAAKDKWEAEKIHIGFRQAYKPPIMPVNYFLDGERQLGTRLMELRNLNYYDTPLEELRKQRGVRVVHLQ
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Xenon and halogenated alkanes track putative substrate binding cavities in the soluble methane monooxygenase hydroxylase.
pubmed doi rcsb
molecule tags Oxidoreductase
molecule keywords METHANE MONOOXYGENASE COMPONENT A, ALPHA CHAIN
total genus 61
structure length 165
sequence length 165
chains with identical sequence F
ec nomenclature ec 1.14.13.25: Methane monooxygenase (soluble).
pdb deposition date 2000-10-03

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
E PF02964 MeMO_Hyd_G Methane monooxygenase, hydrolase gamma chain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1280.10 Mainly Alpha Up-down Bundle Monooxygenase Monooxygenase 1fzhE01
1.20.1280.30 Mainly Alpha Up-down Bundle Monooxygenase Monooxygenase 1fzhE02
1MHYG 1FZ6E 1FZ8E 4GAMC 1XMFE 1XMGE 1MHZG 1XU5E 1FYZE 1XMHE 1XVGE 1XVEE 1FZ3E 1FZ9E 1MMOG 1FZ5E 1FZ2E 1FZIE 1XVFE 1XVDE 1MTYG 1FZ4E 1FZ1E 1FZ0E 1FZHE 1XU3E 1FZ7E 1XVCE 1XVBE
chains in the Genus database with same CATH superfamily
1JW2A 3L2OB 4FK4A 3CFRA 2DEBA 4RNGA 5IREA 4FJ7A 4DU3A 2JPNA 4JS4A 2B7MA 3C94A 4GAMC 4AKGA 1XMFE 2LF6A 2JQTA 3OGMB 2QXFA 4FVMA 4I9LA 3SI6A 1Q9YA 2MMBA 3L0MA 4ADNA 4DTSA 1LDKE 3C95A 3SUNA 4KHYA 4M3WA 4AKHA 4JRPA 3SUPA 1XVEE 4DTRA 3OGLB 4DTOA 2H4TA 1FZ3E 1MMOG 2OZSA 3QEPA 1FZIE 1XVFE 4FK2A 3KD5E 4FJGA 1XVDE 3QETA 3TJYA 2P5OA 3NDKA 1IG9A 1FZ0E 2JHAA 4ICGC 3QNNA 4EP9A 1XVCE 4DTPA 3NGIA 3LZJA 2JHPA 3TAFA 2DTUA 3NE6A 4EPHA 2PFTA 4FJJA 3CFOA 4FK0A 3C6OB 4J2EA 2ATQA 3NAEA 3LZIA 4FJNA 1FZ6E 1FZ8E 4DTNA 1CLQA 2DY4A 4DU1A 3TABA 2E31A 2P1QB 4M3RA 4E4BA 3SCXA 3SQ4A 3RMAA 4I6JB 3RMBA 3HGKE 2JHCA 4M3TA 4FJXA 1XMHE 4FJ5A 2OYQA 4RL5A 3RMCA 4KHWA 4DTUA 4J2BA 2OZMA 1FS1A 2FW3A 3SVIA 5IZ7A 1WAFA 4J2DA 2P1PB 3RWUA 3E4YA 2E32A 2PFVA 2LF3A 3OGKB 4I9QA 1MTYG 1FZ1E 4KI4A 1FZHE 5IBKB 4KI6A 3J27A 4HCCA 2VIXA 3TAEA 3SUQA 3LDSA 4FJIA 4DTMA 4M42A 2YB5A 4JS5A 4X5NA 4QNCA 3TL8B 4FJMA 2MZWB 2HD0A 3QEXA 3SQ1A 3QEIA 4DTJA 4FJLA 2JH9A 3UO2A 3NCIA 3UIQA 3SUOA 1FYZE 2OVQB 1NEXB 2VJ4A 2RCUA 4EYWA 4E3SA 2B8IA 4HCBA 4AI6A 3SNNA 3QESA 3NHGA 1FPOA 4DU4A 3C6NB 2OVPB 1FZ5E 2JH8A 3SPZA 1N1CA 3SQ0A 4FJKA 3UO3A 3QEWA 3KD1E 3N1BA 4ADOA 4IT5A 3HL8A 2MW2A 4M41A 3HP9A 2VJ5A 4KHQA 3CFPA 3V7DB 3SPYA 3HGLA 1XVBE 2FYOA 3QEVA 4JRQA 4M3XA 3RMDA 2P5GA 4QNDA 1MHYG 3S9HA 5H37A 2RKHA 1IH7A 3LDBA 3LD8A 4FJ8A 4M3YA 4J2AA 1XMGE 1MHZG 1XU5E 1WAJA 3QNOA 4M45A 1P22A 4B08A 3WSOA 2P1OB 1XVGE 3E4WA 3K2OA 3N1EA 4FJHA 4KHSA 1FXXA 2P1NB 3C6PB 3MKSB 4KHUA 4M3ZA 3CQ8A 3J2PA 1FZ9E 3L8BA 1FZ2E 2B1EA 3L1NA 3SQ2A 3SJJA 4AKIA 4RG8A 3QERA 2K5SA 3TAGA 1FZ4E 2OVRB 2P1MB 1XU3E 4FJ9A 4X5MA 4DTXA 1FZ7E 3BVOA 1Q9XA 4M3UA 1XL3C 4KHNA
chains in the Genus database with same CATH topology
3L2OB 4FK4A 3CFRA 2DEBA 4RNGA 5IREA 4FJ7A 4DU3A 2JPNA 4JS4A 2B7MA 3C94A 4GAMC 4AKGA 1XMFE 2LF6A 3OGMB 4I9LA 2QXFA 4FVMA 3SI6A 1Q9YA 2MMBA 3L0MA 4ADNA 4DTSA 1LDKE 3C95A 3SUNA 4KHYA 4M3WA 4AKHA 4JRPA 3SUPA 1XVEE 4DTRA 3OGLB 4DTOA 2H4TA 1FZ3E 1MMOG 2OZSA 3QEPA 1FZIE 1XVFE 4FK2A 3KD5E 4FJGA 1XVDE 3QETA 3TJYA 2P5OA 3NDKA 1IG9A 1FZ0E 2JHAA 3QNNA 4EP9A 1XVCE 4DTPA 3NGIA 3LZJA 2JHPA 3TAFA 2DTUA 3NE6A 4EPHA 2PFTA 4FJJA 3CFOA 4FK0A 3C6OB 4J2EA 2ATQA 3NAEA 3LZIA 4FJNA 1FZ6E 1FZ8E 4DTNA 1CLQA 2DY4A 4DU1A 3TABA 2E31A 2P1QB 4M3RA 4E4BA 3SCXA 3SQ4A 3RMAA 4I6JB 3RMBA 3HGKE 2JHCA 4M3TA 4FJXA 1XMHE 4FJ5A 2OYQA 4RL5A 3RMCA 4KHWA 4DTUA 4J2BA 2OZMA 1FS1A 2FW3A 3SVIA 5IZ7A 1WAFA 4J2DA 2P1PB 3RWUA 3E4YA 2E32A 2PFVA 2LF3A 3OGKB 4I9QA 1MTYG 1FZ1E 4KI4A 1FZHE 5IBKB 4KI6A 3J27A 4HCCA 2VIXA 3TAEA 3SUQA 3LDSA 4FJIA 4DTMA 4M42A 2YB5A 4JS5A 4X5NA 4QNCA 3TL8B 4FJMA 2MZWB 2HD0A 3QEXA 3SQ1A 3QEIA 4DTJA 4FJLA 2JH9A 3NCIA 3UIQA 3SUOA 1FYZE 2OVQB 1NEXB 2VJ4A 2RCUA 4EYWA 4E3SA 2B8IA 4HCBA 4AI6A 3SNNA 3QESA 3NHGA 4DU4A 3C6NB 2OVPB 1FZ5E 2JH8A 3SPZA 3SQ0A 4FJKA 3QEWA 3KD1E 3N1BA 4ADOA 3HL8A 4M41A 3HP9A 2VJ5A 4KHQA 3CFPA 3V7DB 3SPYA 3HGLA 1XVBE 2FYOA 3QEVA 4JRQA 4M3XA 3RMDA 2P5GA 4QNDA 1MHYG 3S9HA 5H37A 1IH7A 3LDBA 3LD8A 4FJ8A 4M3YA 4J2AA 1XMGE 1MHZG 1XU5E 1WAJA 3QNOA 4M45A 1P22A 4B08A 3WSOA 2P1OB 1XVGE 3E4WA 3K2OA 3N1EA 4FJHA 4KHSA 1FXXA 2P1NB 3C6PB 3MKSB 4KHUA 4M3ZA 3CQ8A 3J2PA 1FZ9E 3L8BA 1FZ2E 2B1EA 3L1NA 3SQ2A 3SJJA 4AKIA 4RG8A 3QERA 3TAGA 1FZ4E 2OVRB 2P1MB 1XU3E 4FJ9A 4X5MA 4DTXA 1FZ7E 1Q9XA 4M3UA 1XL3C 4KHNA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1MHY G;  1FZ6 E;  1FZ8 E;  4GAM C;  1XMF E;  1XMG E;  1MHZ G;  1XU5 E;  1FYZ E;  1XMH E;  1XVG E;  1XVE E;  1FZ3 E;  1FZ9 E;  1MMO G;  1FZ5 E;  1FZ2 E;  1FZI E;  1XVF E;  1XVD E;  1MTY G;  1FZ4 E;  1FZ1 E;  1FZ0 E;  1FZH E;  1XU3 E;  1FZ7 E;  1XVC E;  1XVB E; 
#chains in the Genus database with same CATH topology
 1JW2 A;  3L2O B;  4FK4 A;  3CFR A;  2DEB A;  4RNG A;  5IRE A;  4FJ7 A;  4DU3 A;  2JPN A;  4JS4 A;  2B7M A;  3C94 A;  4GAM C;  4AKG A;  1XMF E;  2LF6 A;  2JQT A;  3OGM B;  2QXF A;  4FVM A;  4I9L A;  3SI6 A;  1Q9Y A;  2MMB A;  3L0M A;  4ADN A;  4DTS A;  1LDK E;  3C95 A;  3SUN A;  4KHY A;  4M3W A;  4AKH A;  4JRP A;  3SUP A;  1XVE E;  4DTR A;  3OGL B;  4DTO A;  2H4T A;  1FZ3 E;  1MMO G;  2OZS A;  3QEP A;  1FZI E;  1XVF E;  4FK2 A;  3KD5 E;  4FJG A;  1XVD E;  3QET A;  3TJY A;  2P5O A;  3NDK A;  1IG9 A;  1FZ0 E;  2JHA A;  4ICG C;  3QNN A;  4EP9 A;  1XVC E;  4DTP A;  3NGI A;  3LZJ A;  2JHP A;  3TAF A;  2DTU A;  3NE6 A;  4EPH A;  2PFT A;  4FJJ A;  3CFO A;  4FK0 A;  3C6O B;  4J2E A;  2ATQ A;  3NAE A;  3LZI A;  4FJN A;  1FZ6 E;  1FZ8 E;  4DTN A;  1CLQ A;  2DY4 A;  4DU1 A;  3TAB A;  2E31 A;  2P1Q B;  4M3R A;  4E4B A;  3SCX A;  3SQ4 A;  3RMA A;  4I6J B;  3RMB A;  3HGK E;  2JHC A;  4M3T A;  4FJX A;  1XMH E;  4FJ5 A;  2OYQ A;  4RL5 A;  3RMC A;  4KHW A;  4DTU A;  4J2B A;  2OZM A;  1FS1 A;  2FW3 A;  3SVI A;  5IZ7 A;  1WAF A;  4J2D A;  2P1P B;  3RWU A;  3E4Y A;  2E32 A;  2PFV A;  2LF3 A;  3OGK B;  4I9Q A;  1MTY G;  1FZ1 E;  4KI4 A;  1FZH E;  5IBK B;  4KI6 A;  3J27 A;  4HCC A;  2VIX A;  3TAE A;  3SUQ A;  3LDS A;  4FJI A;  4DTM A;  4M42 A;  2YB5 A;  4JS5 A;  4X5N A;  4QNC A;  3TL8 B;  4FJM A;  2MZW B;  2HD0 A;  3QEX A;  3SQ1 A;  3QEI A;  4DTJ A;  4FJL A;  2JH9 A;  3UO2 A;  3NCI A;  3UIQ A;  3SUO A;  1FYZ E;  2OVQ B;  1NEX B;  2VJ4 A;  2RCU A;  4EYW A;  4E3S A;  2B8I A;  4HCB A;  4AI6 A;  3SNN A;  3QES A;  3NHG A;  1FPO A;  4DU4 A;  3C6N B;  2OVP B;  1FZ5 E;  2JH8 A;  3SPZ A;  1N1C A;  3SQ0 A;  4FJK A;  3UO3 A;  3QEW A;  3KD1 E;  3N1B A;  4ADO A;  4IT5 A;  3HL8 A;  2MW2 A;  4M41 A;  3HP9 A;  2VJ5 A;  4KHQ A;  3CFP A;  3V7D B;  3SPY A;  3HGL A;  1XVB E;  2FYO A;  3QEV A;  4JRQ A;  4M3X A;  3RMD A;  2P5G A;  4QND A;  1MHY G;  3S9H A;  5H37 A;  2RKH A;  1IH7 A;  3LDB A;  3LD8 A;  4FJ8 A;  4M3Y A;  4J2A A;  1XMG E;  1MHZ G;  1XU5 E;  1WAJ A;  3QNO A;  4M45 A;  1P22 A;  4B08 A;  3WSO A;  2P1O B;  1XVG E;  3E4W A;  3K2O A;  3N1E A;  4FJH A;  4KHS A;  1FXX A;  2P1N B;  3C6P B;  3MKS B;  4KHU A;  4M3Z A;  3CQ8 A;  3J2P A;  1FZ9 E;  3L8B A;  1FZ2 E;  2B1E A;  3L1N A;  3SQ2 A;  3SJJ A;  4AKI A;  4RG8 A;  3QER A;  2K5S A;  3TAG A;  1FZ4 E;  2OVR B;  2P1M B;  1XU3 E;  4FJ9 A;  4X5M A;  4DTX A;  1FZ7 E;  3BVO A;  1Q9X A;  4M3U A;  1XL3 C;  4KHN A; 
#chains in the Genus database with same CATH homology
 3L2O B;  4FK4 A;  3CFR A;  2DEB A;  4RNG A;  5IRE A;  4FJ7 A;  4DU3 A;  2JPN A;  4JS4 A;  2B7M A;  3C94 A;  4GAM C;  4AKG A;  1XMF E;  2LF6 A;  3OGM B;  4I9L A;  2QXF A;  4FVM A;  3SI6 A;  1Q9Y A;  2MMB A;  3L0M A;  4ADN A;  4DTS A;  1LDK E;  3C95 A;  3SUN A;  4KHY A;  4M3W A;  4AKH A;  4JRP A;  3SUP A;  1XVE E;  4DTR A;  3OGL B;  4DTO A;  2H4T A;  1FZ3 E;  1MMO G;  2OZS A;  3QEP A;  1FZI E;  1XVF E;  4FK2 A;  3KD5 E;  4FJG A;  1XVD E;  3QET A;  3TJY A;  2P5O A;  3NDK A;  1IG9 A;  1FZ0 E;  2JHA A;  3QNN A;  4EP9 A;  1XVC E;  4DTP A;  3NGI A;  3LZJ A;  2JHP A;  3TAF A;  2DTU A;  3NE6 A;  4EPH A;  2PFT A;  4FJJ A;  3CFO A;  4FK0 A;  3C6O B;  4J2E A;  2ATQ A;  3NAE A;  3LZI A;  4FJN A;  1FZ6 E;  1FZ8 E;  4DTN A;  1CLQ A;  2DY4 A;  4DU1 A;  3TAB A;  2E31 A;  2P1Q B;  4M3R A;  4E4B A;  3SCX A;  3SQ4 A;  3RMA A;  4I6J B;  3RMB A;  3HGK E;  2JHC A;  4M3T A;  4FJX A;  1XMH E;  4FJ5 A;  2OYQ A;  4RL5 A;  3RMC A;  4KHW A;  4DTU A;  4J2B A;  2OZM A;  1FS1 A;  2FW3 A;  3SVI A;  5IZ7 A;  1WAF A;  4J2D A;  2P1P B;  3RWU A;  3E4Y A;  2E32 A;  2PFV A;  2LF3 A;  3OGK B;  4I9Q A;  1MTY G;  1FZ1 E;  4KI4 A;  1FZH E;  5IBK B;  4KI6 A;  3J27 A;  4HCC A;  2VIX A;  3TAE A;  3SUQ A;  3LDS A;  4FJI A;  4DTM A;  4M42 A;  2YB5 A;  4JS5 A;  4X5N A;  4QNC A;  3TL8 B;  4FJM A;  2MZW B;  2HD0 A;  3QEX A;  3SQ1 A;  3QEI A;  4DTJ A;  4FJL A;  2JH9 A;  3NCI A;  3UIQ A;  3SUO A;  1FYZ E;  2OVQ B;  1NEX B;  2VJ4 A;  2RCU A;  4EYW A;  4E3S A;  2B8I A;  4HCB A;  4AI6 A;  3SNN A;  3QES A;  3NHG A;  4DU4 A;  3C6N B;  2OVP B;  1FZ5 E;  2JH8 A;  3SPZ A;  3SQ0 A;  4FJK A;  3QEW A;  3KD1 E;  3N1B A;  4ADO A;  3HL8 A;  4M41 A;  3HP9 A;  2VJ5 A;  4KHQ A;  3CFP A;  3V7D B;  3SPY A;  3HGL A;  1XVB E;  2FYO A;  3QEV A;  4JRQ A;  4M3X A;  3RMD A;  2P5G A;  4QND A;  1MHY G;  3S9H A;  5H37 A;  1IH7 A;  3LDB A;  3LD8 A;  4FJ8 A;  4M3Y A;  4J2A A;  1XMG E;  1MHZ G;  1XU5 E;  1WAJ A;  3QNO A;  4M45 A;  1P22 A;  4B08 A;  3WSO A;  2P1O B;  1XVG E;  3E4W A;  3K2O A;  3N1E A;  4FJH A;  4KHS A;  1FXX A;  2P1N B;  3C6P B;  3MKS B;  4KHU A;  4M3Z A;  3CQ8 A;  3J2P A;  1FZ9 E;  3L8B A;  1FZ2 E;  2B1E A;  3L1N A;  3SQ2 A;  3SJJ A;  4AKI A;  4RG8 A;  3QER A;  3TAG A;  1FZ4 E;  2OVR B;  2P1M B;  1XU3 E;  4FJ9 A;  4X5M A;  4DTX A;  1FZ7 E;  1Q9X A;  4M3U A;  1XL3 C;  4KHN A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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