2PFTA

The crystal structure of mouse exo70 reveals unique features of the mammalian exocyst
Total Genus 222
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
222
sequence length
568
structure length
519
Chain Sequence
DHVISYYHVASDTEKIIREGPTGRLEEYLGSMAKIQKAVEYFQDNSPDSPELNKVKLLFERGKESLESEFRSLMTRHSKVVSPVLLLDLISADDELEHLPESVLRDVVRISRWLVEYGRNQDFMNVYYQIRSSQLDRSIKGLKEHFRKSLDVETDAYIHCVSAFVKLAQSEYRLLMEIIPEHHQKKTFDSLIQDALDGLMLEGENIVSAARKAIIRHDFSTVLTVFPILRHLKQTKPEFDQVLQGTAASTKNKLPGLITSMETIGAKALEDFADNIKNDPDKEYNMPKDGTVHELTSNAILFLQQLLDFQETAGAMLASQESSEFSKRLLSTYICKVLGNLQLNLLSKSKVYEDPALSAIFLHNNYNYILKSLEKSELIQLVAVTQKTAERSYREHIEQQIQTYQRSWLKVTDYIAEKNLPVFQPGVKLRDKERQMIKERFKGFNDGLEELCKIQKVWAIPDTEQRDKIRQAQKDIVKETYGAFLHRYGSVPFTKNPEKYIKYRVEQVGDMIDRLFDTS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The crystal structure of mouse Exo70 reveals unique features of the mammalian exocyst.
pubmed doi rcsb
source organism Mus musculus
molecule tags Endocytosis/exocytosis
molecule keywords Exocytosis Protein
total genus 222
structure length 519
sequence length 568
ec nomenclature
pdb deposition date 2007-04-05

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03081 Exo70 Exo70 exocyst complex subunit
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1280.170 Mainly Alpha Up-down Bundle Monooxygenase Monooxygenase 2pftA00
4RL5A 2B1EA 2B7MA 2PFTA 2PFVA
chains in the Genus database with same CATH superfamily
4EP9A 3TJYA 4FJ9A 4RL5A 3UO3A 3UO2A 3NAEA 3SI6A 2JHPA 3N1EA 4I9LA 4FJIA 4FK0A 4KHUA 3RMDA 2H4TA 2OYQA 2QXFA 5IZ7A 3SUOA 1XVCE 4M3RA 1FZHE 3QEPA 4FJHA 1FZ5E 3SVIA 2DY4A 3L1NA 3HL8A 4KHWA 4M3XA 4QNDA 4E4BA 1XMGE 2E31A 3QEIA 3S9HA 2FYOA 2P1PB 3QEVA 3NGIA 1FZ1E 2B1EA 4B08A 4AKHA 4DU3A 2JH9A 2DEBA 3QETA 3HGKE 2VJ5A 2OZMA 3J2PA 3E4WA 4J2AA 4KHYA 2OZSA 4FJLA 3L8BA 4AKIA 3SQ1A 3NDKA 4HCCA 3NE6A 1IH7A 2RKHA 2MMBA 1XL3C 3SUNA 1FXXA 3RMBA 1FZ7E 3QNOA 4FJKA 4FJXA 4M41A 2HD0A 3QERA 4M3ZA 5H37A 2OVPB 2PFTA 1Q9XA 4JS4A 2YB5A 3QEXA 1FYZE 4HCBA 2LF3A 3HGLA 1MHYG 1FPOA 4AKGA 4DTOA 4FJ8A 1XVEE 4AI6A 2E32A 2P1MB 4RG8A 2P1OB 4EPHA 3TAGA 4DTRA 4FJNA 3SCXA 4ADOA 1XVDE 3SQ2A 4DTJA 2P1NB 3K2OA 3OGLB 4KI4A 2MZWB 3J27A 2P5GA 1XU3E 3SQ0A 3QESA 4FJMA 4KI6A 2FW3A 3QEWA 3L0MA 4DTUA 1XU5E 3OGKB 2JPNA 4DU4A 4FJJA 1WAJA 2ATQA 3CFPA 4JRPA 3E4YA 3SQ4A 3RMCA 4FJ5A 4FVMA 3KD5E 3CFOA 1IG9A 1XVGE 3MKSB 3TABA 1FZ3E 3CQ8A 4JS5A 4M42A 1FZ4E 1N1CA 3N1BA 4I6JB 4J2BA 3SPYA 3TL8B 4GAMC 4EYWA 3V7DB 3SJJA 4FK2A 2RCUA 2K5SA 2VJ4A 3WSOA 1MTYG 4J2EA 2OVQB 4KHSA 3RMAA 2JHAA 4M3UA 4X5MA 4DTXA 3L2OB 2B7MA 4X5NA 3NHGA 3TAFA 4DTSA 3TAEA 3LDSA 4M3YA 2DTUA 1WAFA 2JQTA 1FZ8E 1P22A 4I9QA 1FZ0E 2LF6A 1MHZG 1NEXB 1XMFE 5IBKB 3SPZA 3CFRA 1XVFE 2PFVA 2OVRB 3NCIA 4JRQA 3SUPA 2MW2A 3LZIA 3C95A 4QNCA 1FZ9E 1XMHE 4ICGC 4DTPA 3SNNA 1FZ2E 3KD1E 3OGMB 4KHQA 4M3TA 4IT5A 4DU1A 3C6OB 3UIQA 3HP9A 3BVOA 5IREA 4DTNA 3LDBA 3C94A 2B8IA 4M3WA 1CLQA 4RNGA 1JW2A 1LDKE 4M45A 3SUQA 2JH8A 2VIXA 2P5OA 4FJGA 4FJ7A 1Q9YA 3QNNA 3LZJA 4DTMA 1FZ6E 2JHCA 3C6PB 3RWUA 1FZIE 2P1QB 3LD8A 4FK4A 4E3SA 1MMOG 4J2DA 4ADNA 4KHNA 3C6NB 1FS1A 1XVBE
chains in the Genus database with same CATH topology
4EP9A 3TJYA 4FJ9A 4RL5A 3NAEA 3SI6A 2JHPA 3N1EA 4I9LA 4FJIA 4FK0A 4KHUA 3RMDA 2H4TA 2OYQA 2QXFA 5IZ7A 3SUOA 1XVCE 4M3RA 1FZHE 3QEPA 4FJHA 1FZ5E 3SVIA 2DY4A 3L1NA 3HL8A 4KHWA 4M3XA 4QNDA 4E4BA 1XMGE 2E31A 3QEIA 3S9HA 2FYOA 2P1PB 3QEVA 3NGIA 1FZ1E 2B1EA 4B08A 4AKHA 4DU3A 2JH9A 2DEBA 3QETA 3HGKE 2VJ5A 2OZMA 3J2PA 3E4WA 4J2AA 4KHYA 2OZSA 4FJLA 3L8BA 4AKIA 3SQ1A 3NDKA 4HCCA 3NE6A 1IH7A 2MMBA 1XL3C 3SUNA 1FXXA 3RMBA 1FZ7E 3QNOA 4FJKA 4FJXA 4M41A 2HD0A 3QERA 4M3ZA 5H37A 2OVPB 2PFTA 1Q9XA 4JS4A 2YB5A 3QEXA 1FYZE 4HCBA 2LF3A 3HGLA 1MHYG 4AKGA 4DTOA 4FJ8A 1XVEE 4AI6A 2E32A 2P1MB 4RG8A 2P1OB 4EPHA 3TAGA 4DTRA 4FJNA 3SCXA 4ADOA 1XVDE 3SQ2A 4DTJA 2P1NB 3K2OA 3OGLB 4KI4A 2MZWB 3J27A 2P5GA 1XU3E 3SQ0A 3QESA 4FJMA 4KI6A 2FW3A 3QEWA 3L0MA 4DTUA 1XU5E 3OGKB 2JPNA 4DU4A 4FJJA 1WAJA 2ATQA 3CFPA 4JRPA 3E4YA 3SQ4A 3RMCA 4FJ5A 4FVMA 3KD5E 3CFOA 1IG9A 1XVGE 3MKSB 3TABA 1FZ3E 3CQ8A 4JS5A 4M42A 1FZ4E 3N1BA 4I6JB 4J2BA 3SPYA 3TL8B 4GAMC 4EYWA 3V7DB 3SJJA 4FK2A 2RCUA 2VJ4A 3WSOA 4J2EA 1MTYG 4KHSA 2OVQB 4M3UA 3RMAA 2JHAA 4X5MA 4DTXA 3L2OB 2B7MA 4X5NA 3NHGA 3TAFA 4DTSA 3TAEA 3LDSA 4M3YA 2DTUA 1WAFA 4I9QA 1FZ8E 1P22A 1FZ0E 2LF6A 1MHZG 1NEXB 1XMFE 5IBKB 3SPZA 3CFRA 1XVFE 2PFVA 2OVRB 3NCIA 4JRQA 3SUPA 3LZIA 3C95A 4QNCA 1FZ9E 1XMHE 4DTPA 3SNNA 1FZ2E 3KD1E 3OGMB 4KHQA 4M3TA 4DU1A 3C6OB 3UIQA 3HP9A 5IREA 4DTNA 3LDBA 3C94A 2B8IA 4M3WA 1CLQA 4RNGA 1LDKE 4M45A 3SUQA 2JH8A 2VIXA 2P5OA 4FJGA 4FJ7A 1Q9YA 3QNNA 3LZJA 4DTMA 1FZ6E 2JHCA 3C6PB 3RWUA 1FZIE 2P1QB 3LD8A 4FK4A 4E3SA 1MMOG 4J2DA 4ADNA 4KHNA 3C6NB 1FS1A 1XVBE
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4RL5 A;  2B1E A;  2B7M A;  2PFT A;  2PFV A; 
#chains in the Genus database with same CATH topology
 4EP9 A;  3TJY A;  4FJ9 A;  4RL5 A;  3UO3 A;  3UO2 A;  3NAE A;  3SI6 A;  2JHP A;  3N1E A;  4I9L A;  4FJI A;  4FK0 A;  4KHU A;  3RMD A;  2H4T A;  2OYQ A;  2QXF A;  5IZ7 A;  3SUO A;  1XVC E;  4M3R A;  1FZH E;  3QEP A;  4FJH A;  1FZ5 E;  3SVI A;  2DY4 A;  3L1N A;  3HL8 A;  4KHW A;  4M3X A;  4QND A;  4E4B A;  1XMG E;  2E31 A;  3QEI A;  3S9H A;  2FYO A;  2P1P B;  3QEV A;  3NGI A;  1FZ1 E;  2B1E A;  4B08 A;  4AKH A;  4DU3 A;  2JH9 A;  2DEB A;  3QET A;  3HGK E;  2VJ5 A;  2OZM A;  3J2P A;  3E4W A;  4J2A A;  4KHY A;  2OZS A;  4FJL A;  3L8B A;  4AKI A;  3SQ1 A;  3NDK A;  4HCC A;  3NE6 A;  1IH7 A;  2RKH A;  2MMB A;  1XL3 C;  3SUN A;  1FXX A;  3RMB A;  1FZ7 E;  3QNO A;  4FJK A;  4FJX A;  4M41 A;  2HD0 A;  3QER A;  4M3Z A;  5H37 A;  2OVP B;  2PFT A;  1Q9X A;  4JS4 A;  2YB5 A;  3QEX A;  1FYZ E;  4HCB A;  2LF3 A;  3HGL A;  1MHY G;  1FPO A;  4AKG A;  4DTO A;  4FJ8 A;  1XVE E;  4AI6 A;  2E32 A;  2P1M B;  4RG8 A;  2P1O B;  4EPH A;  3TAG A;  4DTR A;  4FJN A;  3SCX A;  4ADO A;  1XVD E;  3SQ2 A;  4DTJ A;  2P1N B;  3K2O A;  3OGL B;  4KI4 A;  2MZW B;  3J27 A;  2P5G A;  1XU3 E;  3SQ0 A;  3QES A;  4FJM A;  4KI6 A;  2FW3 A;  3QEW A;  3L0M A;  4DTU A;  1XU5 E;  3OGK B;  2JPN A;  4DU4 A;  4FJJ A;  1WAJ A;  2ATQ A;  3CFP A;  4JRP A;  3E4Y A;  3SQ4 A;  3RMC A;  4FJ5 A;  4FVM A;  3KD5 E;  3CFO A;  1IG9 A;  1XVG E;  3MKS B;  3TAB A;  1FZ3 E;  3CQ8 A;  4JS5 A;  4M42 A;  1FZ4 E;  1N1C A;  3N1B A;  4I6J B;  4J2B A;  3SPY A;  3TL8 B;  4GAM C;  4EYW A;  3V7D B;  3SJJ A;  4FK2 A;  2RCU A;  2K5S A;  2VJ4 A;  3WSO A;  1MTY G;  4J2E A;  2OVQ B;  4KHS A;  3RMA A;  2JHA A;  4M3U A;  4X5M A;  4DTX A;  3L2O B;  2B7M A;  4X5N A;  3NHG A;  3TAF A;  4DTS A;  3TAE A;  3LDS A;  4M3Y A;  2DTU A;  1WAF A;  2JQT A;  1FZ8 E;  1P22 A;  4I9Q A;  1FZ0 E;  2LF6 A;  1MHZ G;  1NEX B;  1XMF E;  5IBK B;  3SPZ A;  3CFR A;  1XVF E;  2PFV A;  2OVR B;  3NCI A;  4JRQ A;  3SUP A;  2MW2 A;  3LZI A;  3C95 A;  4QNC A;  1FZ9 E;  1XMH E;  4ICG C;  4DTP A;  3SNN A;  1FZ2 E;  3KD1 E;  3OGM B;  4KHQ A;  4M3T A;  4IT5 A;  4DU1 A;  3C6O B;  3UIQ A;  3HP9 A;  3BVO A;  5IRE A;  4DTN A;  3LDB A;  3C94 A;  2B8I A;  4M3W A;  1CLQ A;  4RNG A;  1JW2 A;  1LDK E;  4M45 A;  3SUQ A;  2JH8 A;  2VIX A;  2P5O A;  4FJG A;  4FJ7 A;  1Q9Y A;  3QNN A;  3LZJ A;  4DTM A;  1FZ6 E;  2JHC A;  3C6P B;  3RWU A;  1FZI E;  2P1Q B;  3LD8 A;  4FK4 A;  4E3S A;  1MMO G;  4J2D A;  4ADN A;  4KHN A;  3C6N B;  1FS1 A;  1XVB E; 
#chains in the Genus database with same CATH homology
 4EP9 A;  3TJY A;  4FJ9 A;  4RL5 A;  3NAE A;  3SI6 A;  2JHP A;  3N1E A;  4I9L A;  4FJI A;  4FK0 A;  4KHU A;  3RMD A;  2H4T A;  2OYQ A;  2QXF A;  5IZ7 A;  3SUO A;  1XVC E;  4M3R A;  1FZH E;  3QEP A;  4FJH A;  1FZ5 E;  3SVI A;  2DY4 A;  3L1N A;  3HL8 A;  4KHW A;  4M3X A;  4QND A;  4E4B A;  1XMG E;  2E31 A;  3QEI A;  3S9H A;  2FYO A;  2P1P B;  3QEV A;  3NGI A;  1FZ1 E;  2B1E A;  4B08 A;  4AKH A;  4DU3 A;  2JH9 A;  2DEB A;  3QET A;  3HGK E;  2VJ5 A;  2OZM A;  3J2P A;  3E4W A;  4J2A A;  4KHY A;  2OZS A;  4FJL A;  3L8B A;  4AKI A;  3SQ1 A;  3NDK A;  4HCC A;  3NE6 A;  1IH7 A;  2MMB A;  1XL3 C;  3SUN A;  1FXX A;  3RMB A;  1FZ7 E;  3QNO A;  4FJK A;  4FJX A;  4M41 A;  2HD0 A;  3QER A;  4M3Z A;  5H37 A;  2OVP B;  2PFT A;  1Q9X A;  4JS4 A;  2YB5 A;  3QEX A;  1FYZ E;  4HCB A;  2LF3 A;  3HGL A;  1MHY G;  4AKG A;  4DTO A;  4FJ8 A;  1XVE E;  4AI6 A;  2E32 A;  2P1M B;  4RG8 A;  2P1O B;  4EPH A;  3TAG A;  4DTR A;  4FJN A;  3SCX A;  4ADO A;  1XVD E;  3SQ2 A;  4DTJ A;  2P1N B;  3K2O A;  3OGL B;  4KI4 A;  2MZW B;  3J27 A;  2P5G A;  1XU3 E;  3SQ0 A;  3QES A;  4FJM A;  4KI6 A;  2FW3 A;  3QEW A;  3L0M A;  4DTU A;  1XU5 E;  3OGK B;  2JPN A;  4DU4 A;  4FJJ A;  1WAJ A;  2ATQ A;  3CFP A;  4JRP A;  3E4Y A;  3SQ4 A;  3RMC A;  4FJ5 A;  4FVM A;  3KD5 E;  3CFO A;  1IG9 A;  1XVG E;  3MKS B;  3TAB A;  1FZ3 E;  3CQ8 A;  4JS5 A;  4M42 A;  1FZ4 E;  3N1B A;  4I6J B;  4J2B A;  3SPY A;  3TL8 B;  4GAM C;  4EYW A;  3V7D B;  3SJJ A;  4FK2 A;  2RCU A;  2VJ4 A;  3WSO A;  4J2E A;  1MTY G;  4KHS A;  2OVQ B;  4M3U A;  3RMA A;  2JHA A;  4X5M A;  4DTX A;  3L2O B;  2B7M A;  4X5N A;  3NHG A;  3TAF A;  4DTS A;  3TAE A;  3LDS A;  4M3Y A;  2DTU A;  1WAF A;  4I9Q A;  1FZ8 E;  1P22 A;  1FZ0 E;  2LF6 A;  1MHZ G;  1NEX B;  1XMF E;  5IBK B;  3SPZ A;  3CFR A;  1XVF E;  2PFV A;  2OVR B;  3NCI A;  4JRQ A;  3SUP A;  3LZI A;  3C95 A;  4QNC A;  1FZ9 E;  1XMH E;  4DTP A;  3SNN A;  1FZ2 E;  3KD1 E;  3OGM B;  4KHQ A;  4M3T A;  4DU1 A;  3C6O B;  3UIQ A;  3HP9 A;  5IRE A;  4DTN A;  3LDB A;  3C94 A;  2B8I A;  4M3W A;  1CLQ A;  4RNG A;  1LDK E;  4M45 A;  3SUQ A;  2JH8 A;  2VIX A;  2P5O A;  4FJG A;  4FJ7 A;  1Q9Y A;  3QNN A;  3LZJ A;  4DTM A;  1FZ6 E;  2JHC A;  3C6P B;  3RWU A;  1FZI E;  2P1Q B;  3LD8 A;  4FK4 A;  4E3S A;  1MMO G;  4J2D A;  4ADN A;  4KHN A;  3C6N B;  1FS1 A;  1XVB E; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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