2PFTA

The crystal structure of mouse exo70 reveals unique features of the mammalian exocyst
Total Genus 222
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
222
sequence length
568
structure length
519
Chain Sequence
DHVISYYHVASDTEKIIREGPTGRLEEYLGSMAKIQKAVEYFQDNSPDSPELNKVKLLFERGKESLESEFRSLMTRHSKVVSPVLLLDLISADDELEHLPESVLRDVVRISRWLVEYGRNQDFMNVYYQIRSSQLDRSIKGLKEHFRKSLDVETDAYIHCVSAFVKLAQSEYRLLMEIIPEHHQKKTFDSLIQDALDGLMLEGENIVSAARKAIIRHDFSTVLTVFPILRHLKQTKPEFDQVLQGTAASTKNKLPGLITSMETIGAKALEDFADNIKNDPDKEYNMPKDGTVHELTSNAILFLQQLLDFQETAGAMLASQESSEFSKRLLSTYICKVLGNLQLNLLSKSKVYEDPALSAIFLHNNYNYILKSLEKSELIQLVAVTQKTAERSYREHIEQQIQTYQRSWLKVTDYIAEKNLPVFQPGVKLRDKERQMIKERFKGFNDGLEELCKIQKVWAIPDTEQRDKIRQAQKDIVKETYGAFLHRYGSVPFTKNPEKYIKYRVEQVGDMIDRLFDTS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Endocytosis/exocytosis
molecule keywords Exocytosis Protein
publication title The crystal structure of mouse Exo70 reveals unique features of the mammalian exocyst.
pubmed doi rcsb
source organism Mus musculus
total genus 222
structure length 519
sequence length 568
ec nomenclature
pdb deposition date 2007-04-05

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03081 Exo70 Exo70 exocyst complex subunit
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1280.170 Mainly Alpha Up-down Bundle Monooxygenase Monooxygenase 2pftA00
4RL5A 2PFTA 2B7MA 2B1EA 2PFVA
chains in the Genus database with same CATH superfamily
3UO3A 4QNCA 4FJXA 4AKHA 2OVQB 4DTOA 1N1CA 3QNOA 4DTSA 1FZ6E 1FXXA 3J27A 1FPOA 2PFTA 3TL8B 2OYQA 4FJ7A 4DTXA 4FJ5A 3L1NA 2FYOA 3TAFA 4QNDA 1FZ7E 4I9LA 4KI4A 4KHUA 4FJ8A 3TABA 4HCBA 1IG9A 4M3YA 5IBKB 4M41A 1Q9YA 4J2AA 2LF3A 1CLQA 4JRPA 1FYZE 1WAFA 3CFPA 3QEXA 4KI6A 1FZ1E 2QXFA 4RNGA 1FZ4E 3QETA 3TAGA 4FJIA 4FJHA 3MKSB 1XVFE 3L8BA 1WAJA 1XL3C 1MTYG 5IZ7A 4DTPA 3SJJA 4KHSA 1P22A 3LDSA 4JS4A 4I6JB 2P1NB 4M3ZA 3N1EA 2LF6A 2HD0A 4DU3A 3RMDA 4ADOA 3SQ0A 1XVEE 1Q9XA 4J2BA 3LZJA 4DTJA 5IREA 3S9HA 3SQ4A 3QERA 3CFOA 3SPZA 4I9QA 2VIXA 2P1QB 4GAMC 2MZWB 4FJ9A 4EP9A 3C94A 2YB5A 3TJYA 3SQ2A 1MMOG 3C95A 1LDKE 1FS1A 4DU4A 1FZ5E 3L2OB 2JHAA 4EYWA 3TAEA 3SPYA 2E31A 2P1PB 3WSOA 4ADNA 4FJNA 4IT5A 2MW2A 2DEBA 3NCIA 4RG8A 2P5OA 1XU5E 4KHYA 1XVDE 2DTUA 3E4YA 4E3SA 4FJMA 3NGIA 3SI6A 2JH8A 3SCXA 1XMHE 2OZMA 4M3RA 4FK4A 3QEIA 1MHZG 2H4TA 4M3UA 3KD5E 2E32A 2JH9A 2MMBA 3OGLB 1XMGE 4FVMA 5H37A 3LZIA 3QEWA 4DTUA 4DTRA 3C6OB 4KHNA 1MHYG 1FZ8E 3NDKA 4AI6A 1XU3E 3OGKB 2RCUA 1XMFE 3SQ1A 4FJKA 1XVBE 2VJ4A 1IH7A 2ATQA 3RWUA 4KHWA 2P1OB 3UO2A 1XVCE 3C6NB 1NEXB 1JW2A 2RKHA 4RL5A 4M3TA 2JHCA 3HP9A 4X5MA 3CQ8A 3C6PB 3HL8A 2B7MA 3HGLA 3LD8A 3RMAA 4E4BA 4DTMA 1FZ9E 2P5GA 3BVOA 4EPHA 3K2OA 2PFVA 3N1BA 4B08A 4JRQA 2B1EA 4M45A 4JS5A 3NHGA 3RMCA 4FK0A 4AKIA 3SUQA 4DTNA 3SUOA 4M3XA 3QNNA 2FW3A 4DU1A 1FZ3E 1XVGE 3HGKE 2JHPA 3L0MA 4J2DA 4X5NA 4FJLA 3KD1E 4FJJA 2K5SA 3UIQA 2P1MB 4HCCA 2OVRB 1FZHE 3CFRA 3RMBA 4M3WA 4FK2A 3OGMB 3SVIA 3QEPA 4M42A 3V7DB 3QEVA 2DY4A 2B8IA 3SUPA 1FZ2E 2JQTA 3LDBA 4ICGC 1FZIE 4FJGA 4KHQA 3QESA 4J2EA 3E4WA 4AKGA 3J2PA 1FZ0E 2OVPB 3SUNA 2JPNA 3SNNA 3NE6A 2OZSA 2VJ5A 3NAEA
chains in the Genus database with same CATH topology
4QNCA 4FJXA 4AKHA 2OVQB 4DTOA 3QNOA 4DTSA 1FZ6E 1FXXA 3J27A 2PFTA 3TL8B 2OYQA 4FJ7A 4DTXA 4FJ5A 3L1NA 2FYOA 3TAFA 4QNDA 1FZ7E 4I9LA 4KI4A 4KHUA 4FJ8A 3TABA 4HCBA 1IG9A 4M3YA 5IBKB 4M41A 1Q9YA 4J2AA 2LF3A 1CLQA 4JRPA 1FYZE 1WAFA 3CFPA 3QEXA 4KI6A 1FZ1E 2QXFA 4RNGA 1FZ4E 3QETA 3TAGA 4FJIA 4FJHA 3MKSB 1XVFE 3L8BA 1WAJA 1XL3C 1MTYG 5IZ7A 4DTPA 3SJJA 4KHSA 1P22A 3LDSA 4JS4A 4I6JB 2P1NB 4M3ZA 3N1EA 2LF6A 2HD0A 4DU3A 3RMDA 4ADOA 3SQ0A 1XVEE 1Q9XA 4J2BA 3LZJA 4DTJA 5IREA 3S9HA 3SQ4A 3QERA 3CFOA 3SPZA 4I9QA 2VIXA 2P1QB 4GAMC 2MZWB 4FJ9A 4EP9A 3C94A 2YB5A 3TJYA 3SQ2A 1MMOG 3C95A 1LDKE 1FS1A 4DU4A 1FZ5E 3L2OB 2JHAA 4EYWA 3TAEA 3SPYA 2E31A 2P1PB 3WSOA 4ADNA 4FJNA 2DEBA 3NCIA 4RG8A 2P5OA 1XU5E 4KHYA 1XVDE 2DTUA 3E4YA 4E3SA 4FJMA 3NGIA 3SI6A 2JH8A 3SCXA 1XMHE 2OZMA 4M3RA 4FK4A 3QEIA 1MHZG 2H4TA 4M3UA 3KD5E 2E32A 2JH9A 2MMBA 3OGLB 1XMGE 4FVMA 5H37A 3LZIA 3QEWA 4DTUA 4DTRA 3C6OB 4KHNA 1MHYG 1FZ8E 3NDKA 4AI6A 1XU3E 3OGKB 2RCUA 1XMFE 3SQ1A 4FJKA 1XVBE 2VJ4A 1IH7A 2ATQA 3RWUA 4KHWA 2P1OB 1XVCE 3C6NB 1NEXB 4RL5A 4M3TA 2JHCA 3HP9A 4X5MA 3CQ8A 3C6PB 3HL8A 2B7MA 3HGLA 3LD8A 3RMAA 4E4BA 4DTMA 1FZ9E 2P5GA 4EPHA 3K2OA 2PFVA 3N1BA 4B08A 4JRQA 2B1EA 4M45A 4JS5A 3NHGA 3RMCA 4FK0A 4AKIA 3SUQA 4DTNA 3SUOA 4M3XA 3QNNA 2FW3A 4DU1A 1FZ3E 1XVGE 3HGKE 2JHPA 3L0MA 4J2DA 4X5NA 4FJLA 3KD1E 4FJJA 3UIQA 2P1MB 4HCCA 2OVRB 1FZHE 3CFRA 3RMBA 4M3WA 4FK2A 3OGMB 3SVIA 3QEPA 4M42A 3V7DB 3QEVA 2DY4A 2B8IA 3SUPA 1FZ2E 3LDBA 4FJGA 4KHQA 1FZIE 3QESA 4J2EA 3E4WA 4AKGA 3J2PA 1FZ0E 2OVPB 3SUNA 2JPNA 3SNNA 3NE6A 2OZSA 2VJ5A 3NAEA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4RL5 A;  2PFT A;  2B7M A;  2B1E A;  2PFV A; 
#chains in the Genus database with same CATH topology
 3UO3 A;  4QNC A;  4FJX A;  4AKH A;  2OVQ B;  4DTO A;  1N1C A;  3QNO A;  4DTS A;  1FZ6 E;  1FXX A;  3J27 A;  1FPO A;  2PFT A;  3TL8 B;  2OYQ A;  4FJ7 A;  4DTX A;  4FJ5 A;  3L1N A;  2FYO A;  3TAF A;  4QND A;  1FZ7 E;  4I9L A;  4KI4 A;  4KHU A;  4FJ8 A;  3TAB A;  4HCB A;  1IG9 A;  4M3Y A;  5IBK B;  4M41 A;  1Q9Y A;  4J2A A;  2LF3 A;  1CLQ A;  4JRP A;  1FYZ E;  1WAF A;  3CFP A;  3QEX A;  4KI6 A;  1FZ1 E;  2QXF A;  4RNG A;  1FZ4 E;  3QET A;  3TAG A;  4FJI A;  4FJH A;  3MKS B;  1XVF E;  3L8B A;  1WAJ A;  1XL3 C;  1MTY G;  5IZ7 A;  4DTP A;  3SJJ A;  4KHS A;  1P22 A;  3LDS A;  4JS4 A;  4I6J B;  2P1N B;  4M3Z A;  3N1E A;  2LF6 A;  2HD0 A;  4DU3 A;  3RMD A;  4ADO A;  3SQ0 A;  1XVE E;  1Q9X A;  4J2B A;  3LZJ A;  4DTJ A;  5IRE A;  3S9H A;  3SQ4 A;  3QER A;  3CFO A;  3SPZ A;  4I9Q A;  2VIX A;  2P1Q B;  4GAM C;  2MZW B;  4FJ9 A;  4EP9 A;  3C94 A;  2YB5 A;  3TJY A;  3SQ2 A;  1MMO G;  3C95 A;  1LDK E;  1FS1 A;  4DU4 A;  1FZ5 E;  3L2O B;  2JHA A;  4EYW A;  3TAE A;  3SPY A;  2E31 A;  2P1P B;  3WSO A;  4ADN A;  4FJN A;  4IT5 A;  2MW2 A;  2DEB A;  3NCI A;  4RG8 A;  2P5O A;  1XU5 E;  4KHY A;  1XVD E;  2DTU A;  3E4Y A;  4E3S A;  4FJM A;  3NGI A;  3SI6 A;  2JH8 A;  3SCX A;  1XMH E;  2OZM A;  4M3R A;  4FK4 A;  3QEI A;  1MHZ G;  2H4T A;  4M3U A;  3KD5 E;  2E32 A;  2JH9 A;  2MMB A;  3OGL B;  1XMG E;  4FVM A;  5H37 A;  3LZI A;  3QEW A;  4DTU A;  4DTR A;  3C6O B;  4KHN A;  1MHY G;  1FZ8 E;  3NDK A;  4AI6 A;  1XU3 E;  3OGK B;  2RCU A;  1XMF E;  3SQ1 A;  4FJK A;  1XVB E;  2VJ4 A;  1IH7 A;  2ATQ A;  3RWU A;  4KHW A;  2P1O B;  3UO2 A;  1XVC E;  3C6N B;  1NEX B;  1JW2 A;  2RKH A;  4RL5 A;  4M3T A;  2JHC A;  3HP9 A;  4X5M A;  3CQ8 A;  3C6P B;  3HL8 A;  2B7M A;  3HGL A;  3LD8 A;  3RMA A;  4E4B A;  4DTM A;  1FZ9 E;  2P5G A;  3BVO A;  4EPH A;  3K2O A;  2PFV A;  3N1B A;  4B08 A;  4JRQ A;  2B1E A;  4M45 A;  4JS5 A;  3NHG A;  3RMC A;  4FK0 A;  4AKI A;  3SUQ A;  4DTN A;  3SUO A;  4M3X A;  3QNN A;  2FW3 A;  4DU1 A;  1FZ3 E;  1XVG E;  3HGK E;  2JHP A;  3L0M A;  4J2D A;  4X5N A;  4FJL A;  3KD1 E;  4FJJ A;  2K5S A;  3UIQ A;  2P1M B;  4HCC A;  2OVR B;  1FZH E;  3CFR A;  3RMB A;  4M3W A;  4FK2 A;  3OGM B;  3SVI A;  3QEP A;  4M42 A;  3V7D B;  3QEV A;  2DY4 A;  2B8I A;  3SUP A;  1FZ2 E;  2JQT A;  3LDB A;  4ICG C;  1FZI E;  4FJG A;  4KHQ A;  3QES A;  4J2E A;  3E4W A;  4AKG A;  3J2P A;  1FZ0 E;  2OVP B;  3SUN A;  2JPN A;  3SNN A;  3NE6 A;  2OZS A;  2VJ5 A;  3NAE A; 
#chains in the Genus database with same CATH homology
 4QNC A;  4FJX A;  4AKH A;  2OVQ B;  4DTO A;  3QNO A;  4DTS A;  1FZ6 E;  1FXX A;  3J27 A;  2PFT A;  3TL8 B;  2OYQ A;  4FJ7 A;  4DTX A;  4FJ5 A;  3L1N A;  2FYO A;  3TAF A;  4QND A;  1FZ7 E;  4I9L A;  4KI4 A;  4KHU A;  4FJ8 A;  3TAB A;  4HCB A;  1IG9 A;  4M3Y A;  5IBK B;  4M41 A;  1Q9Y A;  4J2A A;  2LF3 A;  1CLQ A;  4JRP A;  1FYZ E;  1WAF A;  3CFP A;  3QEX A;  4KI6 A;  1FZ1 E;  2QXF A;  4RNG A;  1FZ4 E;  3QET A;  3TAG A;  4FJI A;  4FJH A;  3MKS B;  1XVF E;  3L8B A;  1WAJ A;  1XL3 C;  1MTY G;  5IZ7 A;  4DTP A;  3SJJ A;  4KHS A;  1P22 A;  3LDS A;  4JS4 A;  4I6J B;  2P1N B;  4M3Z A;  3N1E A;  2LF6 A;  2HD0 A;  4DU3 A;  3RMD A;  4ADO A;  3SQ0 A;  1XVE E;  1Q9X A;  4J2B A;  3LZJ A;  4DTJ A;  5IRE A;  3S9H A;  3SQ4 A;  3QER A;  3CFO A;  3SPZ A;  4I9Q A;  2VIX A;  2P1Q B;  4GAM C;  2MZW B;  4FJ9 A;  4EP9 A;  3C94 A;  2YB5 A;  3TJY A;  3SQ2 A;  1MMO G;  3C95 A;  1LDK E;  1FS1 A;  4DU4 A;  1FZ5 E;  3L2O B;  2JHA A;  4EYW A;  3TAE A;  3SPY A;  2E31 A;  2P1P B;  3WSO A;  4ADN A;  4FJN A;  2DEB A;  3NCI A;  4RG8 A;  2P5O A;  1XU5 E;  4KHY A;  1XVD E;  2DTU A;  3E4Y A;  4E3S A;  4FJM A;  3NGI A;  3SI6 A;  2JH8 A;  3SCX A;  1XMH E;  2OZM A;  4M3R A;  4FK4 A;  3QEI A;  1MHZ G;  2H4T A;  4M3U A;  3KD5 E;  2E32 A;  2JH9 A;  2MMB A;  3OGL B;  1XMG E;  4FVM A;  5H37 A;  3LZI A;  3QEW A;  4DTU A;  4DTR A;  3C6O B;  4KHN A;  1MHY G;  1FZ8 E;  3NDK A;  4AI6 A;  1XU3 E;  3OGK B;  2RCU A;  1XMF E;  3SQ1 A;  4FJK A;  1XVB E;  2VJ4 A;  1IH7 A;  2ATQ A;  3RWU A;  4KHW A;  2P1O B;  1XVC E;  3C6N B;  1NEX B;  4RL5 A;  4M3T A;  2JHC A;  3HP9 A;  4X5M A;  3CQ8 A;  3C6P B;  3HL8 A;  2B7M A;  3HGL A;  3LD8 A;  3RMA A;  4E4B A;  4DTM A;  1FZ9 E;  2P5G A;  4EPH A;  3K2O A;  2PFV A;  3N1B A;  4B08 A;  4JRQ A;  2B1E A;  4M45 A;  4JS5 A;  3NHG A;  3RMC A;  4FK0 A;  4AKI A;  3SUQ A;  4DTN A;  3SUO A;  4M3X A;  3QNN A;  2FW3 A;  4DU1 A;  1FZ3 E;  1XVG E;  3HGK E;  2JHP A;  3L0M A;  4J2D A;  4X5N A;  4FJL A;  3KD1 E;  4FJJ A;  3UIQ A;  2P1M B;  4HCC A;  2OVR B;  1FZH E;  3CFR A;  3RMB A;  4M3W A;  4FK2 A;  3OGM B;  3SVI A;  3QEP A;  4M42 A;  3V7D B;  3QEV A;  2DY4 A;  2B8I A;  3SUP A;  1FZ2 E;  3LDB A;  4FJG A;  4KHQ A;  1FZI E;  3QES A;  4J2E A;  3E4W A;  4AKG A;  3J2P A;  1FZ0 E;  2OVP B;  3SUN A;  2JPN A;  3SNN A;  3NE6 A;  2OZS A;  2VJ5 A;  3NAE A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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