2PFTA

The crystal structure of mouse exo70 reveals unique features of the mammalian exocyst
Total Genus 222
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
222
sequence length
568
structure length
519
Chain Sequence
DHVISYYHVASDTEKIIREGPTGRLEEYLGSMAKIQKAVEYFQDNSPDSPELNKVKLLFERGKESLESEFRSLMTRHSKVVSPVLLLDLISADDELEHLPESVLRDVVRISRWLVEYGRNQDFMNVYYQIRSSQLDRSIKGLKEHFRKSLDVETDAYIHCVSAFVKLAQSEYRLLMEIIPEHHQKKTFDSLIQDALDGLMLEGENIVSAARKAIIRHDFSTVLTVFPILRHLKQTKPEFDQVLQGTAASTKNKLPGLITSMETIGAKALEDFADNIKNDPDKEYNMPKDGTVHELTSNAILFLQQLLDFQETAGAMLASQESSEFSKRLLSTYICKVLGNLQLNLLSKSKVYEDPALSAIFLHNNYNYILKSLEKSELIQLVAVTQKTAERSYREHIEQQIQTYQRSWLKVTDYIAEKNLPVFQPGVKLRDKERQMIKERFKGFNDGLEELCKIQKVWAIPDTEQRDKIRQAQKDIVKETYGAFLHRYGSVPFTKNPEKYIKYRVEQVGDMIDRLFDTS
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
molecule keywords Exocytosis Protein
publication title The crystal structure of mouse Exo70 reveals unique features of the mammalian exocyst.
pubmed doi rcsb
source organism Mus musculus
molecule tags Endocytosis/exocytosis
total genus 222
structure length 519
sequence length 568
ec nomenclature
pdb deposition date 2007-04-05

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03081 Exo70 Exo70 exocyst complex subunit
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1280.170 Mainly Alpha Up-down Bundle Monooxygenase Monooxygenase 2pftA00
2PFVA 2B7MA 2B1EA 2PFTA 4RL5A
chains in the Genus database with same CATH superfamily
4FJ8A 5IREA 2LF3A 3NCIA 3TAGA 4DTPA 2ATQA 4M45A 4QNCA 2P1OB 3UO3A 4FJXA 4FJIA 2P1PB 2JPNA 2FYOA 3UO2A 3QEIA 4FK0A 4DU4A 2K5SA 1FZ3E 2E31A 4AKHA 4FJGA 1XVGE 2JHAA 3NHGA 1XVEE 1XL3C 3SNNA 4DTJA 2PFTA 5IZ7A 4EP9A 2P5OA 4JS4A 4DTOA 2P1NB 3QNNA 4M42A 3SQ1A 2B7MA 3KD5E 4FK2A 3OGKB 3RWUA 4DTUA 2DEBA 4DTNA 4JS5A 2OZSA 4M3TA 2MZWB 3QEWA 4FJNA 1LDKE 1FZ1E 1WAFA 4KHUA 2P5GA 2B1EA 2VIXA 4I9QA 2YB5A 3QNOA 2VJ5A 3TAFA 4RNGA 1FZ0E 4J2AA 1WAJA 1XVBE 3MKSB 4J2BA 1FZ4E 2OVRB 4JRQA 1MTYG 3SUQA 1MHZG 3K2OA 3C6OB 1FZ6E 2P1QB 3WSOA 4KHNA 4M3YA 4KI6A 3J2PA 2B8IA 3HP9A 3OGMB 2FW3A 4M3UA 4GAMC 3SQ4A 4AI6A 4J2EA 3OGLB 3NE6A 4AKGA 3NDKA 3QESA 4FJMA 3QETA 3L8BA 2QXFA 1IH7A 3NAEA 1P22A 1FS1A 3HGKE 1N1CA 4M41A 3QERA 3L2OB 1FZIE 4DU1A 4DTRA 3UIQA 3C6NB 2PFVA 1FZHE 3L1NA 4B08A 2DY4A 3SJJA 5IBKB 2OZMA 1XVFE 2JH8A 3SQ0A 3N1BA 3HL8A 1FYZE 4I6JB 1FZ2E 3E4YA 4QNDA 3RMDA 4M3WA 3E4WA 1JW2A 3S9HA 3TABA 1IG9A 1FZ8E 4FJ5A 4X5MA 2RKHA 2E32A 3C95A 3TAEA 1FXXA 1FZ5E 4ADNA 1XMGE 1XU5E 2OVPB 2P1MB 2VJ4A 4JRPA 2JH9A 3KD1E 2OVQB 3SQ2A 1NEXB 3QEPA 2RCUA 2JHCA 3CQ8A 3SUNA 3C94A 4FJHA 1XU3E 3LZIA 1Q9YA 4FJJA 4KHWA 4ADOA 4DTXA 3SUOA 4KI4A 1XVDE 1XMFE 3TL8B 4J2DA 3SPYA 1MMOG 3V7DB 1XMHE 4HCBA 1CLQA 4AKIA 4FJ9A 2OYQA 4KHQA 2JHPA 3QEXA 4M3RA 3RMBA 3NGIA 4FJLA 2HD0A 3N1EA 4DU3A 3J27A 3L0MA 3SI6A 3HGLA 1XVCE 4RL5A 3CFOA 4FVMA 3SCXA 1FZ7E 3CFPA 3TJYA 3LZJA 2MW2A 4EYWA 4I9LA 3SPZA 3RMCA 2H4TA 1Q9XA 2DTUA 4KHSA 3RMAA 4E3SA 2JQTA 3C6PB 4X5NA 4EPHA 4FJKA 4ICGC 3LDSA 4DTMA 4KHYA 3LD8A 3CFRA 3BVOA 4DTSA 4IT5A 3SUPA 4FK4A 2LF6A 4RG8A 4FJ7A 3QEVA 3LDBA 2MMBA 4HCCA 4M3XA 4E4BA 5H37A 1FPOA 1MHYG 4M3ZA 1FZ9E 3SVIA
chains in the Genus database with same CATH topology
4FJ8A 5IREA 2LF3A 3NCIA 3TAGA 4DTPA 2ATQA 4M45A 4QNCA 2P1OB 4FJXA 4FJIA 2P1PB 2JPNA 2FYOA 3QEIA 4FK0A 4DU4A 4AKHA 1FZ3E 2E31A 4FJGA 1XVGE 2JHAA 3NHGA 1XVEE 1XL3C 3SNNA 4DTJA 2PFTA 5IZ7A 4EP9A 2P5OA 4JS4A 4DTOA 2P1NB 3QNNA 4M42A 3SQ1A 2B7MA 3KD5E 4FK2A 3OGKB 3RWUA 4DTUA 2DEBA 4DTNA 4JS5A 2OZSA 4M3TA 2MZWB 3QEWA 4FJNA 1LDKE 1FZ1E 1WAFA 4KHUA 2P5GA 2B1EA 2VIXA 4I9QA 2YB5A 3QNOA 2VJ5A 3TAFA 4RNGA 1FZ0E 4J2AA 1WAJA 1XVBE 3MKSB 4J2BA 1FZ4E 2OVRB 4JRQA 1MTYG 3SUQA 1MHZG 3K2OA 3C6OB 1FZ6E 2P1QB 3WSOA 4KHNA 4M3YA 4KI6A 3J2PA 2B8IA 3HP9A 3OGMB 2FW3A 4M3UA 4GAMC 3SQ4A 4AI6A 4J2EA 3OGLB 3NE6A 4AKGA 3NDKA 3QESA 4FJMA 3QETA 3L8BA 2QXFA 1IH7A 3NAEA 1P22A 1FS1A 3HGKE 4M41A 3QERA 3L2OB 1FZIE 4DU1A 4DTRA 3UIQA 3C6NB 2PFVA 1FZHE 3L1NA 4B08A 2DY4A 3SJJA 5IBKB 2OZMA 1XVFE 2JH8A 3SQ0A 3N1BA 3HL8A 1FYZE 4I6JB 1FZ2E 3E4YA 4QNDA 3RMDA 4M3WA 3E4WA 3S9HA 3TABA 1IG9A 1FZ8E 4FJ5A 4X5MA 2E32A 3C95A 3TAEA 1FXXA 1FZ5E 4ADNA 1XMGE 1XU5E 2OVPB 2P1MB 2VJ4A 4JRPA 2JH9A 3KD1E 2OVQB 3SQ2A 1NEXB 3QEPA 2RCUA 2JHCA 3CQ8A 3SUNA 3C94A 4FJHA 1XU3E 3LZIA 1Q9YA 4FJJA 4KHWA 4ADOA 4DTXA 3SUOA 4KI4A 1XVDE 1XMFE 3TL8B 4J2DA 3SPYA 1MMOG 3V7DB 1XMHE 4HCBA 1CLQA 4AKIA 4FJ9A 2OYQA 4KHQA 2JHPA 3QEXA 4M3RA 3RMBA 3NGIA 4FJLA 2HD0A 3N1EA 4DU3A 3J27A 3L0MA 3SI6A 3HGLA 1XVCE 4RL5A 3CFOA 4FVMA 3SCXA 1FZ7E 3CFPA 3TJYA 3LZJA 4EYWA 4I9LA 3SPZA 3RMCA 2H4TA 1Q9XA 2DTUA 4KHSA 3RMAA 4E3SA 4EPHA 3C6PB 4X5NA 4FJKA 4DTMA 3LDSA 4KHYA 3LD8A 3CFRA 4DTSA 3SUPA 4FK4A 2LF6A 4RG8A 4FJ7A 3QEVA 3LDBA 2MMBA 4HCCA 4M3XA 4E4BA 5H37A 1MHYG 4M3ZA 1FZ9E 3SVIA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2PFV A;  2B7M A;  2B1E A;  2PFT A;  4RL5 A; 
#chains in the Genus database with same CATH topology
 4FJ8 A;  5IRE A;  2LF3 A;  3NCI A;  3TAG A;  4DTP A;  2ATQ A;  4M45 A;  4QNC A;  2P1O B;  3UO3 A;  4FJX A;  4FJI A;  2P1P B;  2JPN A;  2FYO A;  3UO2 A;  3QEI A;  4FK0 A;  4DU4 A;  2K5S A;  1FZ3 E;  2E31 A;  4AKH A;  4FJG A;  1XVG E;  2JHA A;  3NHG A;  1XVE E;  1XL3 C;  3SNN A;  4DTJ A;  2PFT A;  5IZ7 A;  4EP9 A;  2P5O A;  4JS4 A;  4DTO A;  2P1N B;  3QNN A;  4M42 A;  3SQ1 A;  2B7M A;  3KD5 E;  4FK2 A;  3OGK B;  3RWU A;  4DTU A;  2DEB A;  4DTN A;  4JS5 A;  2OZS A;  4M3T A;  2MZW B;  3QEW A;  4FJN A;  1LDK E;  1FZ1 E;  1WAF A;  4KHU A;  2P5G A;  2B1E A;  2VIX A;  4I9Q A;  2YB5 A;  3QNO A;  2VJ5 A;  3TAF A;  4RNG A;  1FZ0 E;  4J2A A;  1WAJ A;  1XVB E;  3MKS B;  4J2B A;  1FZ4 E;  2OVR B;  4JRQ A;  1MTY G;  3SUQ A;  1MHZ G;  3K2O A;  3C6O B;  1FZ6 E;  2P1Q B;  3WSO A;  4KHN A;  4M3Y A;  4KI6 A;  3J2P A;  2B8I A;  3HP9 A;  3OGM B;  2FW3 A;  4M3U A;  4GAM C;  3SQ4 A;  4AI6 A;  4J2E A;  3OGL B;  3NE6 A;  4AKG A;  3NDK A;  3QES A;  4FJM A;  3QET A;  3L8B A;  2QXF A;  1IH7 A;  3NAE A;  1P22 A;  1FS1 A;  3HGK E;  1N1C A;  4M41 A;  3QER A;  3L2O B;  1FZI E;  4DU1 A;  4DTR A;  3UIQ A;  3C6N B;  2PFV A;  1FZH E;  3L1N A;  4B08 A;  2DY4 A;  3SJJ A;  5IBK B;  2OZM A;  1XVF E;  2JH8 A;  3SQ0 A;  3N1B A;  3HL8 A;  1FYZ E;  4I6J B;  1FZ2 E;  3E4Y A;  4QND A;  3RMD A;  4M3W A;  3E4W A;  1JW2 A;  3S9H A;  3TAB A;  1IG9 A;  1FZ8 E;  4FJ5 A;  4X5M A;  2RKH A;  2E32 A;  3C95 A;  3TAE A;  1FXX A;  1FZ5 E;  4ADN A;  1XMG E;  1XU5 E;  2OVP B;  2P1M B;  2VJ4 A;  4JRP A;  2JH9 A;  3KD1 E;  2OVQ B;  3SQ2 A;  1NEX B;  3QEP A;  2RCU A;  2JHC A;  3CQ8 A;  3SUN A;  3C94 A;  4FJH A;  1XU3 E;  3LZI A;  1Q9Y A;  4FJJ A;  4KHW A;  4ADO A;  4DTX A;  3SUO A;  4KI4 A;  1XVD E;  1XMF E;  3TL8 B;  4J2D A;  3SPY A;  1MMO G;  3V7D B;  1XMH E;  4HCB A;  1CLQ A;  4AKI A;  4FJ9 A;  2OYQ A;  4KHQ A;  2JHP A;  3QEX A;  4M3R A;  3RMB A;  3NGI A;  4FJL A;  2HD0 A;  3N1E A;  4DU3 A;  3J27 A;  3L0M A;  3SI6 A;  3HGL A;  1XVC E;  4RL5 A;  3CFO A;  4FVM A;  3SCX A;  1FZ7 E;  3CFP A;  3TJY A;  3LZJ A;  2MW2 A;  4EYW A;  4I9L A;  3SPZ A;  3RMC A;  2H4T A;  1Q9X A;  2DTU A;  4KHS A;  3RMA A;  4E3S A;  2JQT A;  3C6P B;  4X5N A;  4EPH A;  4FJK A;  4ICG C;  3LDS A;  4DTM A;  4KHY A;  3LD8 A;  3CFR A;  3BVO A;  4DTS A;  4IT5 A;  3SUP A;  4FK4 A;  2LF6 A;  4RG8 A;  4FJ7 A;  3QEV A;  3LDB A;  2MMB A;  4HCC A;  4M3X A;  4E4B A;  5H37 A;  1FPO A;  1MHY G;  4M3Z A;  1FZ9 E;  3SVI A; 
#chains in the Genus database with same CATH homology
 4FJ8 A;  5IRE A;  2LF3 A;  3NCI A;  3TAG A;  4DTP A;  2ATQ A;  4M45 A;  4QNC A;  2P1O B;  4FJX A;  4FJI A;  2P1P B;  2JPN A;  2FYO A;  3QEI A;  4FK0 A;  4DU4 A;  4AKH A;  1FZ3 E;  2E31 A;  4FJG A;  1XVG E;  2JHA A;  3NHG A;  1XVE E;  1XL3 C;  3SNN A;  4DTJ A;  2PFT A;  5IZ7 A;  4EP9 A;  2P5O A;  4JS4 A;  4DTO A;  2P1N B;  3QNN A;  4M42 A;  3SQ1 A;  2B7M A;  3KD5 E;  4FK2 A;  3OGK B;  3RWU A;  4DTU A;  2DEB A;  4DTN A;  4JS5 A;  2OZS A;  4M3T A;  2MZW B;  3QEW A;  4FJN A;  1LDK E;  1FZ1 E;  1WAF A;  4KHU A;  2P5G A;  2B1E A;  2VIX A;  4I9Q A;  2YB5 A;  3QNO A;  2VJ5 A;  3TAF A;  4RNG A;  1FZ0 E;  4J2A A;  1WAJ A;  1XVB E;  3MKS B;  4J2B A;  1FZ4 E;  2OVR B;  4JRQ A;  1MTY G;  3SUQ A;  1MHZ G;  3K2O A;  3C6O B;  1FZ6 E;  2P1Q B;  3WSO A;  4KHN A;  4M3Y A;  4KI6 A;  3J2P A;  2B8I A;  3HP9 A;  3OGM B;  2FW3 A;  4M3U A;  4GAM C;  3SQ4 A;  4AI6 A;  4J2E A;  3OGL B;  3NE6 A;  4AKG A;  3NDK A;  3QES A;  4FJM A;  3QET A;  3L8B A;  2QXF A;  1IH7 A;  3NAE A;  1P22 A;  1FS1 A;  3HGK E;  4M41 A;  3QER A;  3L2O B;  1FZI E;  4DU1 A;  4DTR A;  3UIQ A;  3C6N B;  2PFV A;  1FZH E;  3L1N A;  4B08 A;  2DY4 A;  3SJJ A;  5IBK B;  2OZM A;  1XVF E;  2JH8 A;  3SQ0 A;  3N1B A;  3HL8 A;  1FYZ E;  4I6J B;  1FZ2 E;  3E4Y A;  4QND A;  3RMD A;  4M3W A;  3E4W A;  3S9H A;  3TAB A;  1IG9 A;  1FZ8 E;  4FJ5 A;  4X5M A;  2E32 A;  3C95 A;  3TAE A;  1FXX A;  1FZ5 E;  4ADN A;  1XMG E;  1XU5 E;  2OVP B;  2P1M B;  2VJ4 A;  4JRP A;  2JH9 A;  3KD1 E;  2OVQ B;  3SQ2 A;  1NEX B;  3QEP A;  2RCU A;  2JHC A;  3CQ8 A;  3SUN A;  3C94 A;  4FJH A;  1XU3 E;  3LZI A;  1Q9Y A;  4FJJ A;  4KHW A;  4ADO A;  4DTX A;  3SUO A;  4KI4 A;  1XVD E;  1XMF E;  3TL8 B;  4J2D A;  3SPY A;  1MMO G;  3V7D B;  1XMH E;  4HCB A;  1CLQ A;  4AKI A;  4FJ9 A;  2OYQ A;  4KHQ A;  2JHP A;  3QEX A;  4M3R A;  3RMB A;  3NGI A;  4FJL A;  2HD0 A;  3N1E A;  4DU3 A;  3J27 A;  3L0M A;  3SI6 A;  3HGL A;  1XVC E;  4RL5 A;  3CFO A;  4FVM A;  3SCX A;  1FZ7 E;  3CFP A;  3TJY A;  3LZJ A;  4EYW A;  4I9L A;  3SPZ A;  3RMC A;  2H4T A;  1Q9X A;  2DTU A;  4KHS A;  3RMA A;  4E3S A;  4EPH A;  3C6P B;  4X5N A;  4FJK A;  4DTM A;  3LDS A;  4KHY A;  3LD8 A;  3CFR A;  4DTS A;  3SUP A;  4FK4 A;  2LF6 A;  4RG8 A;  4FJ7 A;  3QEV A;  3LDB A;  2MMB A;  4HCC A;  4M3X A;  4E4B A;  5H37 A;  1MHY G;  4M3Z A;  1FZ9 E;  3SVI A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...