2X98A

H.salinarum alkaline phosphatase
Total Genus 149
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
149
Knots found
sequence length
430
structure length
430
Chain Sequence
ASPAANAIAYIVDGMGQTQISAARYLNAYKTAPERFPLNVSPAETPTGFDAFSSRGSMTTFPDDPYETTTDSAAAATAFASGVKTYNGAIGGVQTSGGGFQRVDTVLERASAQGYATGLITTTEATHATPAAFAAHVEDRGNQTEIARQYIEETQPDVILGGQRRDFEADASNGGTLVDAARDNGYTIAETAAELDAVDDPPVLGLFSQESHLDYYLDRKNDPENTQPNLDAMVDAGVDLLSSAGDPDKGFFLLVESGRVDHAGHANYPAQVAEQYEATQVAGQLVEYAETTAEPTFLVSTGDHECGGLTLGRDSPYEVEYDVLAAQKATTSRLRDLLAGVRSADELESIVAAHTGITALTDREVAKLRDAPGSISTILAERAGIAFTTDGHTGTDVPVFAHGPNAARFDAARDNTAVADALAAALGVSL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural and Biochemical Characterization of a Halophilic Archaeal Alkaline Phosphatase.
pubmed doi rcsb
molecule tags Hydrolase
source organism Halobacterium salinarum
molecule keywords ALKALINE PHOSPHATASE
total genus 149
structure length 430
sequence length 430
chains with identical sequence B
other databases KnotProt 2.0: S +31
ec nomenclature ec 3.1.3.1: Alkaline phosphatase.
pdb deposition date 2010-03-14

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00245 Alk_phosphatase Alkaline phosphatase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.60.40 Mainly Alpha Orthogonal Bundle Diphtheria Toxin Repressor; domain 2 Diphtheria Toxin Repressor; domain 2 2x98A02
3.40.720.10 Alpha Beta 3-Layer(aba) Sandwich Alkaline Phosphatase, subunit A Alkaline Phosphatase, subunit A 2x98A01
4FDJA 4CXUA 3NKOA 2XR9A 4ZG7A 1N2KA 1KH5A 1HQAA 2W5SA 1SHNA 3ED4A 1AUKA 1AJCA 2QZUA 3IGZB 4LREA 3BDHA 5LIAA 3NKRA 4TN0A 4ZG6A 4NWXA 2D1GA 1ANJA 2XRGA 2W5VA 4GTXA 4CYSA 3UO0A 4GTWA 1HJKA 5INHA 4KJDA 4UPHA 1ZEFA 3E2DA 4FDIA 2IUCA 5GRRA 3MK0A 4QAXA 1ED9A 4KJGA 3DPCA 4CXKA 1E2SP 2W8DA 2GSNA 5IJQA 4UOOA 3IDDA 2W5XA 5GOVA 3LXQA 3BDGA 5DLVA 2VQRA 2W5QA 3NVLA 5C66A 4ZGAA 2X98A 1EW9A 1FSUA 2GA3A 5LRMA 2G9YA 4MY4A 4UOPA 1EI6A 3WAWA 4CXSA 4KAYA 3MK2A 3WAVA 1EW8A 1KHLA 4LR7A 1EJJA 4LRDA 3TX0A 1ELYA 1ELZA 4LR9A 5AJ9A 5L0EA 5LRNA 3M8YA 3UN3A 1EQJA 5HRTA 3SZZA 2GSOA 3OT9A 3WAXA 3B5QA 3T00A 3SZYA 4KM4A 3M7VA 3WBHA 4MIVA 2ZKTA 2W5RA 4UPIA 4YR1A 1ED8A 1EW2A 1KH9A 1O99A 4LRAA 3UN2A 1ELXA 1KH7A 4LRBA 4LQYA 2GSUA 5TJ3A 1E3CP 4CYRA 3NKMA 3KD8A 1Y7AA 1N2LA 1ALJA 4N7TA 3UNYA 4KAVA 3NKQA 4GTZA 1URAA 3M8ZA 3A52A 4UORA 4ZG9A 1SHQA 1Y6VA 2IUCB 1AJAA 4LR8A 1ANIA 2W5TA 1O98A 5L0KA 3DYCA 1P49A 2W8SA 3TWZA 2RH6A 1E33P 4LRCA 3TG0A 4GTYA 1AJBA 3IGYB 3NKNA 5IJSA 1HDHA 1E1ZP 4LR2A 1ZEDA 5L0BA 5LQQA 2IFYA 3BDGB 5KXAA 3CMRA 3UN5A 3M8WA 5EGHA 3BDFA 2GLQA 1ALIA 5EGEA 1ALHA 1K7HA 4LRFA 1KH4A 1KHKA 1KHJA 3NKPA 3WAYA 1AJDA 4UPLA 1URBA 5DLWA 2W5WA 4MHXA 1ZEBA 2ANHA 3MK1A 4UPKA 3T02A 3Q3QA 4B56A 5DLTA 5K4PA 4NWJA 3T01A 1ALKA 1B8JA 1KHNA
chains in the Genus database with same CATH superfamily
4FDJA 4CXUA 3NKOA 2XR9A 3R61A 4O6JA 2QQ9A 1N2KA 1KH5A 4ZG7A 1BI1A 1HQAA 2HYFA 2W5SA 1SHNA 3ED4A 1AUKA 1AJCA 2QZUA 3IGZB 4LREA 3BDHA 4HX8A 1DDNA 3J81R 2F5FA 1BI3A 5LIAA 5IT9R 3NKRA 4TN0A 4ZG6A 4NWXA 2D1GA 1ANJA 4HX7A 2XRGA 5FLXR 2W5VA 1BI0A 4GTXA 4CYSA 1BI2A 2HYGD 4GTWA 3UO0A 1HJKA 5INHA 1FX7A 4KJDA 2MZ4A 4UPHA 1ZEFA 3E2DA 4FDIA 2IUCA 5GRRA 3MK0A 4QAXA 1ED9A 1B1BA 2ISZA 3DPCA 4KJGA 4CXKA 1E2SP 3R60A 2W8DA 2GSNA 5IJQA 4UOOA 3IDDA 5A2QR 2W5XA 5GOVA 1P92A 1U8RA 3JAMR 3LXQA 2MUNA 1G3TA 2DTRA 3BDGA 5DLVA 2VQRA 2W5QA 2F5CA 2QQBA 3NVLA 5C66A 4ZGAA 2X98A 4O5VA 1G3YA 1EW9A 1FSUA 2GA3A 5LRMA 2G9YA 4MY4A 4UOPA 1EI6A 3J80R 3WAWA 4CXSA 4KAYA 3MK2A 3WAVA 1EW8A 1KHLA 4LR7A 1EJJA 4LRDA 3TX0A 1ELYA 1ELZA 4LR9A 5AJ9A 5L0EA 5LRNA 3M8YA 3UN3A 1EQJA 3GLXA 5HRTA 3SZZA 2GSOA 3OT9A 2QQAA 3WAXA 3B5QA 3T00A 3SZYA 4KM4A 2M35A 1G3WA 3M7VA 1DPRA 3WBHA 4MIVA 2ZKTA 2W5RA 4UPIA 4YR1A 1ED8A 1EW2A 1KH9A 3J7AW 1O99A 4LRAA 3UN2A 1ELXA 1KH7A 4LRBA 1G3SA 4LQYA 2EV5A 2GSUA 2EV0A 5TJ3A 1E3CP 1RQ6A 4CYRA 3NKMA 1FWZA 3KD8A 1Y7AA 1N2LA 1ALJA 4N7TA 3UNYA 4HV5A 4KAVA 3NKQA 4GTZA 1URAA 3M8ZA 3A52A 4HV6A 4UORA 4ZG9A 1SHQA 1Y6VA 2IUCB 2EV6A 1AJAA 1F5TA 4LR8A 1ANIA 2MVTA 1O98A 2F5DA 2W5TA 5L0KA 3DYCA 1P49A 2W8SA 3TWZA 2RH6A 1E33P 4LRCA 3TG0A 4GTYA 1AJBA 3IGYB 3NKNA 1C0WA 5IJSA 1HDHA 1E1ZP 4LR2A 1ZEDA 5L0BA 5LQQA 2IFYA 3BDGB 5KXAA 3CMRA 3UN5A 3M8WA 5EGHA 3BDFA 2GLQA 1ALIA 5EGEA 2P0TA 1ALHA 1K7HA 4LRFA 1KH4A 1KHKA 1KHJA 3NKPA 2H09A 1AJDA 3WAYA 4UPLA 1URBA 2TDXA 1ON2A 5DLWA 2W5WA 4MHXA 1ZEBA 1ON1A 2ANHA 3MK1A 4UPKA 3Q3QA 3T02A 4B56A 5DLTA 2F5EA 5K4PA 4HX4A 4NWJA 3T01A 1XCVA 1ALKA 1B8JA 1KHNA
chains in the Genus database with same CATH topology
4FDJA 4CXUA 3NKOA 2XR9A 4ZG7A 1N2KA 1KH5A 1HQAA 2W5SA 1SHNA 3ED4A 1AUKA 1AJCA 2QZUA 3IGZB 4LREA 3BDHA 5LIAA 3NKRA 4TN0A 4ZG6A 4NWXA 2D1GA 1ANJA 2XRGA 2W5VA 4GTXA 4CYSA 3UO0A 4GTWA 1HJKA 5INHA 4KJDA 2MZ4A 4UPHA 1ZEFA 3E2DA 4FDIA 2IUCA 5GRRA 3MK0A 4QAXA 1ED9A 4KJGA 3DPCA 4CXKA 1E2SP 2W8DA 2GSNA 5IJQA 4UOOA 3IDDA 2W5XA 5GOVA 3LXQA 2MUNA 3BDGA 5DLVA 2VQRA 2W5QA 3NVLA 5C66A 4ZGAA 2X98A 1EW9A 1FSUA 2GA3A 5LRMA 2G9YA 4MY4A 4UOPA 1EI6A 3WAWA 4CXSA 4KAYA 3MK2A 3WAVA 1EW8A 1KHLA 4LR7A 1EJJA 4LRDA 3TX0A 1ELYA 1ELZA 4LR9A 5AJ9A 5L0EA 5LRNA 3M8YA 3UN3A 1EQJA 5HRTA 3SZZA 2GSOA 3OT9A 3WAXA 3B5QA 3T00A 3SZYA 4KM4A 2M35A 3M7VA 3WBHA 4MIVA 2ZKTA 2W5RA 4UPIA 4YR1A 1ED8A 1EW2A 1KH9A 1O99A 4LRAA 3UN2A 1ELXA 1KH7A 4LRBA 4LQYA 2GSUA 5TJ3A 1E3CP 4CYRA 3NKMA 3KD8A 1Y7AA 1N2LA 1ALJA 4N7TA 3UNYA 4KAVA 3NKQA 4GTZA 1URAA 3M8ZA 3A52A 4UORA 4ZG9A 1SHQA 1Y6VA 2IUCB 1AJAA 4LR8A 1ANIA 2MVTA 1O98A 2W5TA 5L0KA 3DYCA 1P49A 2W8SA 3TWZA 2RH6A 1E33P 4LRCA 3TG0A 4GTYA 1AJBA 3IGYB 3NKNA 5IJSA 1HDHA 1E1ZP 4LR2A 1ZEDA 5L0BA 5LQQA 2IFYA 3BDGB 5KXAA 3CMRA 3UN5A 3M8WA 5EGHA 3BDFA 2GLQA 1ALIA 5EGEA 1ALHA 1K7HA 4LRFA 1KH4A 1KHKA 1KHJA 3NKPA 3WAYA 1AJDA 4UPLA 1URBA 5DLWA 2W5WA 4MHXA 1ZEBA 2ANHA 3MK1A 4UPKA 3T02A 3Q3QA 4B56A 5DLTA 5K4PA 4NWJA 3T01A 1ALKA 1B8JA 1KHNA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4FDJ A;  4CXU A;  3NKO A;  2XR9 A;  4ZG7 A;  1N2K A;  1KH5 A;  1HQA A;  2W5S A;  1SHN A;  3ED4 A;  1AUK A;  1AJC A;  2QZU A;  3IGZ B;  4LRE A;  3BDH A;  5LIA A;  3NKR A;  4TN0 A;  4ZG6 A;  4NWX A;  2D1G A;  1ANJ A;  2XRG A;  2W5V A;  4GTX A;  4CYS A;  3UO0 A;  4GTW A;  1HJK A;  5INH A;  4KJD A;  4UPH A;  1ZEF A;  3E2D A;  4FDI A;  2IUC A;  5GRR A;  3MK0 A;  4QAX A;  1ED9 A;  4KJG A;  3DPC A;  4CXK A;  1E2S P;  2W8D A;  2GSN A;  5IJQ A;  4UOO A;  3IDD A;  2W5X A;  5GOV A;  3LXQ A;  3BDG A;  5DLV A;  2VQR A;  2W5Q A;  3NVL A;  5C66 A;  4ZGA A;  2X98 A;  1EW9 A;  1FSU A;  2GA3 A;  5LRM A;  2G9Y A;  4MY4 A;  4UOP A;  1EI6 A;  3WAW A;  4CXS A;  4KAY A;  3MK2 A;  3WAV A;  1EW8 A;  1KHL A;  4LR7 A;  1EJJ A;  4LRD A;  3TX0 A;  1ELY A;  1ELZ A;  4LR9 A;  5AJ9 A;  5L0E A;  5LRN A;  3M8Y A;  3UN3 A;  1EQJ A;  5HRT A;  3SZZ A;  2GSO A;  3OT9 A;  3WAX A;  3B5Q A;  3T00 A;  3SZY A;  4KM4 A;  3M7V A;  3WBH A;  4MIV A;  2ZKT A;  2W5R A;  4UPI A;  4YR1 A;  1ED8 A;  1EW2 A;  1KH9 A;  1O99 A;  4LRA A;  3UN2 A;  1ELX A;  1KH7 A;  4LRB A;  4LQY A;  2GSU A;  5TJ3 A;  1E3C P;  4CYR A;  3NKM A;  3KD8 A;  1Y7A A;  1N2L A;  1ALJ A;  4N7T A;  3UNY A;  4KAV A;  3NKQ A;  4GTZ A;  1URA A;  3M8Z A;  3A52 A;  4UOR A;  4ZG9 A;  1SHQ A;  1Y6V A;  2IUC B;  1AJA A;  4LR8 A;  1ANI A;  2W5T A;  1O98 A;  5L0K A;  3DYC A;  1P49 A;  2W8S A;  3TWZ A;  2RH6 A;  1E33 P;  4LRC A;  3TG0 A;  4GTY A;  1AJB A;  3IGY B;  3NKN A;  5IJS A;  1HDH A;  1E1Z P;  4LR2 A;  1ZED A;  5L0B A;  5LQQ A;  2IFY A;  3BDG B;  5KXA A;  3CMR A;  3UN5 A;  3M8W A;  5EGH A;  3BDF A;  2GLQ A;  1ALI A;  5EGE A;  1ALH A;  1K7H A;  4LRF A;  1KH4 A;  1KHK A;  1KHJ A;  3NKP A;  3WAY A;  1AJD A;  4UPL A;  1URB A;  5DLW A;  2W5W A;  4MHX A;  1ZEB A;  2ANH A;  3MK1 A;  4UPK A;  3T02 A;  3Q3Q A;  4B56 A;  5DLT A;  5K4P A;  4NWJ A;  3T01 A;  1ALK A;  1B8J A;  1KHN A; 
#chains in the Genus database with same CATH topology
 4FDJ A;  4CXU A;  3NKO A;  2XR9 A;  3R61 A;  4O6J A;  2QQ9 A;  1N2K A;  1KH5 A;  4ZG7 A;  1BI1 A;  1HQA A;  2HYF A;  2W5S A;  1SHN A;  3ED4 A;  1AUK A;  1AJC A;  2QZU A;  3IGZ B;  4LRE A;  3BDH A;  4HX8 A;  1DDN A;  3J81 R;  2F5F A;  1BI3 A;  5LIA A;  5IT9 R;  3NKR A;  4TN0 A;  4ZG6 A;  4NWX A;  2D1G A;  1ANJ A;  4HX7 A;  2XRG A;  5FLX R;  2W5V A;  1BI0 A;  4GTX A;  4CYS A;  1BI2 A;  2HYG D;  4GTW A;  3UO0 A;  1HJK A;  5INH A;  1FX7 A;  4KJD A;  2MZ4 A;  4UPH A;  1ZEF A;  3E2D A;  4FDI A;  2IUC A;  5GRR A;  3MK0 A;  4QAX A;  1ED9 A;  1B1B A;  2ISZ A;  3DPC A;  4KJG A;  4CXK A;  1E2S P;  3R60 A;  2W8D A;  2GSN A;  5IJQ A;  4UOO A;  3IDD A;  5A2Q R;  2W5X A;  5GOV A;  1P92 A;  1U8R A;  3JAM R;  3LXQ A;  2MUN A;  1G3T A;  2DTR A;  3BDG A;  5DLV A;  2VQR A;  2W5Q A;  2F5C A;  2QQB A;  3NVL A;  5C66 A;  4ZGA A;  2X98 A;  4O5V A;  1G3Y A;  1EW9 A;  1FSU A;  2GA3 A;  5LRM A;  2G9Y A;  4MY4 A;  4UOP A;  1EI6 A;  3J80 R;  3WAW A;  4CXS A;  4KAY A;  3MK2 A;  3WAV A;  1EW8 A;  1KHL A;  4LR7 A;  1EJJ A;  4LRD A;  3TX0 A;  1ELY A;  1ELZ A;  4LR9 A;  5AJ9 A;  5L0E A;  5LRN A;  3M8Y A;  3UN3 A;  1EQJ A;  3GLX A;  5HRT A;  3SZZ A;  2GSO A;  3OT9 A;  2QQA A;  3WAX A;  3B5Q A;  3T00 A;  3SZY A;  4KM4 A;  2M35 A;  1G3W A;  3M7V A;  1DPR A;  3WBH A;  4MIV A;  2ZKT A;  2W5R A;  4UPI A;  4YR1 A;  1ED8 A;  1EW2 A;  1KH9 A;  3J7A W;  1O99 A;  4LRA A;  3UN2 A;  1ELX A;  1KH7 A;  4LRB A;  1G3S A;  4LQY A;  2EV5 A;  2GSU A;  2EV0 A;  5TJ3 A;  1E3C P;  1RQ6 A;  4CYR A;  3NKM A;  1FWZ A;  3KD8 A;  1Y7A A;  1N2L A;  1ALJ A;  4N7T A;  3UNY A;  4HV5 A;  4KAV A;  3NKQ A;  4GTZ A;  1URA A;  3M8Z A;  3A52 A;  4HV6 A;  4UOR A;  4ZG9 A;  1SHQ A;  1Y6V A;  2IUC B;  2EV6 A;  1AJA A;  1F5T A;  4LR8 A;  1ANI A;  2MVT A;  1O98 A;  2F5D A;  2W5T A;  5L0K A;  3DYC A;  1P49 A;  2W8S A;  3TWZ A;  2RH6 A;  1E33 P;  4LRC A;  3TG0 A;  4GTY A;  1AJB A;  3IGY B;  3NKN A;  1C0W A;  5IJS A;  1HDH A;  1E1Z P;  4LR2 A;  1ZED A;  5L0B A;  5LQQ A;  2IFY A;  3BDG B;  5KXA A;  3CMR A;  3UN5 A;  3M8W A;  5EGH A;  3BDF A;  2GLQ A;  1ALI A;  5EGE A;  2P0T A;  1ALH A;  1K7H A;  4LRF A;  1KH4 A;  1KHK A;  1KHJ A;  3NKP A;  2H09 A;  1AJD A;  3WAY A;  4UPL A;  1URB A;  2TDX A;  1ON2 A;  5DLW A;  2W5W A;  4MHX A;  1ZEB A;  1ON1 A;  2ANH A;  3MK1 A;  4UPK A;  3Q3Q A;  3T02 A;  4B56 A;  5DLT A;  2F5E A;  5K4P A;  4HX4 A;  4NWJ A;  3T01 A;  1XCV A;  1ALK A;  1B8J A;  1KHN A; 
#chains in the Genus database with same CATH homology
 4FDJ A;  4CXU A;  3NKO A;  2XR9 A;  4ZG7 A;  1N2K A;  1KH5 A;  1HQA A;  2W5S A;  1SHN A;  3ED4 A;  1AUK A;  1AJC A;  2QZU A;  3IGZ B;  4LRE A;  3BDH A;  5LIA A;  3NKR A;  4TN0 A;  4ZG6 A;  4NWX A;  2D1G A;  1ANJ A;  2XRG A;  2W5V A;  4GTX A;  4CYS A;  3UO0 A;  4GTW A;  1HJK A;  5INH A;  4KJD A;  2MZ4 A;  4UPH A;  1ZEF A;  3E2D A;  4FDI A;  2IUC A;  5GRR A;  3MK0 A;  4QAX A;  1ED9 A;  4KJG A;  3DPC A;  4CXK A;  1E2S P;  2W8D A;  2GSN A;  5IJQ A;  4UOO A;  3IDD A;  2W5X A;  5GOV A;  3LXQ A;  2MUN A;  3BDG A;  5DLV A;  2VQR A;  2W5Q A;  3NVL A;  5C66 A;  4ZGA A;  2X98 A;  1EW9 A;  1FSU A;  2GA3 A;  5LRM A;  2G9Y A;  4MY4 A;  4UOP A;  1EI6 A;  3WAW A;  4CXS A;  4KAY A;  3MK2 A;  3WAV A;  1EW8 A;  1KHL A;  4LR7 A;  1EJJ A;  4LRD A;  3TX0 A;  1ELY A;  1ELZ A;  4LR9 A;  5AJ9 A;  5L0E A;  5LRN A;  3M8Y A;  3UN3 A;  1EQJ A;  5HRT A;  3SZZ A;  2GSO A;  3OT9 A;  3WAX A;  3B5Q A;  3T00 A;  3SZY A;  4KM4 A;  2M35 A;  3M7V A;  3WBH A;  4MIV A;  2ZKT A;  2W5R A;  4UPI A;  4YR1 A;  1ED8 A;  1EW2 A;  1KH9 A;  1O99 A;  4LRA A;  3UN2 A;  1ELX A;  1KH7 A;  4LRB A;  4LQY A;  2GSU A;  5TJ3 A;  1E3C P;  4CYR A;  3NKM A;  3KD8 A;  1Y7A A;  1N2L A;  1ALJ A;  4N7T A;  3UNY A;  4KAV A;  3NKQ A;  4GTZ A;  1URA A;  3M8Z A;  3A52 A;  4UOR A;  4ZG9 A;  1SHQ A;  1Y6V A;  2IUC B;  1AJA A;  4LR8 A;  1ANI A;  2MVT A;  1O98 A;  2W5T A;  5L0K A;  3DYC A;  1P49 A;  2W8S A;  3TWZ A;  2RH6 A;  1E33 P;  4LRC A;  3TG0 A;  4GTY A;  1AJB A;  3IGY B;  3NKN A;  5IJS A;  1HDH A;  1E1Z P;  4LR2 A;  1ZED A;  5L0B A;  5LQQ A;  2IFY A;  3BDG B;  5KXA A;  3CMR A;  3UN5 A;  3M8W A;  5EGH A;  3BDF A;  2GLQ A;  1ALI A;  5EGE A;  1ALH A;  1K7H A;  4LRF A;  1KH4 A;  1KHK A;  1KHJ A;  3NKP A;  3WAY A;  1AJD A;  4UPL A;  1URB A;  5DLW A;  2W5W A;  4MHX A;  1ZEB A;  2ANH A;  3MK1 A;  4UPK A;  3T02 A;  3Q3Q A;  4B56 A;  5DLT A;  5K4P A;  4NWJ A;  3T01 A;  1ALK A;  1B8J A;  1KHN A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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