2PFTA

The crystal structure of mouse exo70 reveals unique features of the mammalian exocyst
Total Genus 222
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
222
sequence length
568
structure length
519
Chain Sequence
DHVISYYHVASDTEKIIREGPTGRLEEYLGSMAKIQKAVEYFQDNSPDSPELNKVKLLFERGKESLESEFRSLMTRHSKVVSPVLLLDLISADDELEHLPESVLRDVVRISRWLVEYGRNQDFMNVYYQIRSSQLDRSIKGLKEHFRKSLDVETDAYIHCVSAFVKLAQSEYRLLMEIIPEHHQKKTFDSLIQDALDGLMLEGENIVSAARKAIIRHDFSTVLTVFPILRHLKQTKPEFDQVLQGTAASTKNKLPGLITSMETIGAKALEDFADNIKNDPDKEYNMPKDGTVHELTSNAILFLQQLLDFQETAGAMLASQESSEFSKRLLSTYICKVLGNLQLNLLSKSKVYEDPALSAIFLHNNYNYILKSLEKSELIQLVAVTQKTAERSYREHIEQQIQTYQRSWLKVTDYIAEKNLPVFQPGVKLRDKERQMIKERFKGFNDGLEELCKIQKVWAIPDTEQRDKIRQAQKDIVKETYGAFLHRYGSVPFTKNPEKYIKYRVEQVGDMIDRLFDTS
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
molecule tags Endocytosis/exocytosis
molecule keywords Exocytosis Protein
publication title The crystal structure of mouse Exo70 reveals unique features of the mammalian exocyst.
pubmed doi rcsb
source organism Mus musculus
total genus 222
structure length 519
sequence length 568
ec nomenclature
pdb deposition date 2007-04-05

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03081 Exo70 Exo70 exocyst complex subunit
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1280.170 Mainly Alpha Up-down Bundle Monooxygenase Monooxygenase 2pftA00
2PFVA 2B7MA 2PFTA 4RL5A 2B1EA
chains in the Genus database with same CATH superfamily
2MW2A 4J2AA 1MHYG 3QEVA 4M3XA 1XVCE 3NDKA 1FZ7E 2HD0A 2P1OB 3C6OB 3E4YA 3SPYA 4I9LA 1IG9A 4FJ8A 3J2PA 1LDKE 4M42A 4M3ZA 2P1QB 4FK2A 2JHAA 2RCUA 4RNGA 3QEPA 3NE6A 2JQTA 4B08A 2K5SA 2P5OA 1FXXA 1FZ3E 2P1NB 2YB5A 4GAMC 3SQ1A 1XMFE 4FJIA 3HP9A 4FJKA 2P1PB 4KHNA 3RMCA 3L0MA 1IH7A 1Q9XA 4DTNA 1WAJA 2VIXA 4KI4A 3LDSA 5IREA 1P22A 3SJJA 4E4BA 3HL8A 1FYZE 4X5NA 4X5MA 3HGLA 4JRPA 4M3WA 3LZJA 1XU3E 2B7MA 3SCXA 3CFOA 1XVBE 1XVGE 1FZ9E 1FZ8E 3HGKE 3LD8A 1FZ2E 2MZWB 3LZIA 4JS5A 4KHSA 2OZMA 4I9QA 1FZIE 4DU1A 4KI6A 3BVOA 3TAFA 4IT5A 4M3RA 3J27A 3CQ8A 3TJYA 4AKGA 3C95A 2QXFA 1XVDE 4AKHA 3TAGA 1FZ5E 2E31A 2JHPA 2E32A 2LF3A 3SVIA 3MKSB 4J2BA 1WAFA 2RKHA 3SQ2A 3TL8B 2FW3A 2DTUA 3RMDA 4M3YA 4DTSA 3OGKB 2PFTA 4EPHA 3SPZA 4FJXA 1N1CA 4FJNA 4M3UA 1JW2A 4JS4A 3NCIA 3SUNA 2JHCA 4FJJA 3C6PB 4FJ7A 4QNCA 4M3TA 3N1EA 3SI6A 1FZHE 4HCCA 1FS1A 1MHZG 1FZ0E 4DU4A 4M41A 3SUQA 1CLQA 4DTRA 2PFVA 3UO2A 3C6NB 4QNDA 1FZ6E 4M45A 3QETA 2VJ5A 3SUPA 1XVEE 3L8BA 3SUOA 3S9HA 3KD1E 3L1NA 3N1BA 1XU5E 2DY4A 3L2OB 2B8IA 3QNNA 4J2EA 3K2OA 3NHGA 3E4WA 3NGIA 3QNOA 3OGMB 3WSOA 2VJ4A 4E3SA 4DTOA 3KD5E 4KHUA 1XMHE 4FVMA 4KHWA 3SQ4A 1FPOA 2ATQA 1XL3C 4EP9A 4KHYA 3NAEA 4JRQA 2JH8A 1MTYG 5H37A 3V7DB 4DU3A 3CFRA 3UO3A 4HCBA 4EYWA 4I6JB 4DTMA 4FJ9A 4J2DA 4KHQA 2B1EA 3TAEA 4ADOA 2DEBA 2OZSA 4FJLA 4RG8A 2JH9A 2FYOA 3SNNA 3TABA 1FZ1E 5IZ7A 3SQ0A 2OVRB 4AI6A 4AKIA 3RWUA 4FK4A 4ADNA 2P1MB 2MMBA 4DTPA 5IBKB 1FZ4E 3LDBA 1XMGE 3RMBA 4ICGC 4DTJA 2P5GA 3QEWA 2LF6A 2OYQA 3UIQA 1MMOG 3QERA 4FJHA 4FJMA 3QESA 4FJGA 4FK0A 3OGLB 1XVFE 4DTXA 3QEIA 1Q9YA 1NEXB 3C94A 2H4TA 4DTUA 2OVPB 2JPNA 3RMAA 4RL5A 3QEXA 4FJ5A 2OVQB 3CFPA
chains in the Genus database with same CATH topology
4J2AA 1MHYG 3QEVA 4M3XA 1XVCE 3NDKA 1FZ7E 3C6OB 2HD0A 2P1OB 3E4YA 3SPYA 4I9LA 1IG9A 4FJ8A 3J2PA 1LDKE 4M42A 4M3ZA 2P1QB 4FK2A 2JHAA 2RCUA 4RNGA 3QEPA 3NE6A 4B08A 2P5OA 1FXXA 1FZ3E 2P1NB 2YB5A 4GAMC 3SQ1A 1XMFE 4FJIA 3HP9A 4FJKA 2P1PB 4KHNA 3RMCA 3L0MA 1IH7A 1Q9XA 4DTNA 1WAJA 2VIXA 4KI4A 3LDSA 5IREA 1P22A 3SJJA 4E4BA 3HL8A 1FYZE 4X5NA 4X5MA 3HGLA 4JRPA 4M3WA 3LZJA 1XU3E 2B7MA 3SCXA 3CFOA 1XVBE 1XVGE 1FZ9E 1FZ8E 3HGKE 3LD8A 1FZ2E 2MZWB 3LZIA 4JS5A 4KHSA 2OZMA 4I9QA 1FZIE 4DU1A 4KI6A 3TAFA 4M3RA 3J27A 3CQ8A 3TJYA 4AKGA 3C95A 2QXFA 1XVDE 4AKHA 3TAGA 1FZ5E 2E31A 2JHPA 2E32A 2LF3A 3SVIA 3MKSB 4J2BA 1WAFA 3SQ2A 3TL8B 2FW3A 2DTUA 3RMDA 4M3YA 4DTSA 3OGKB 2PFTA 4EPHA 3SPZA 4FJXA 4FJNA 4M3UA 4JS4A 3NCIA 3SUNA 2JHCA 4FJJA 3C6PB 4FJ7A 4QNCA 4M3TA 3N1EA 3SI6A 1FZHE 4HCCA 1FS1A 1MHZG 1FZ0E 4DU4A 4M41A 3SUQA 1CLQA 4DTRA 2PFVA 3C6NB 4QNDA 1FZ6E 4M45A 3QETA 2VJ5A 3SUPA 1XVEE 3L8BA 3SUOA 3S9HA 3KD1E 3L1NA 3N1BA 1XU5E 2DY4A 3L2OB 2B8IA 3QNNA 4J2EA 3K2OA 3NHGA 3E4WA 3NGIA 3QNOA 3OGMB 3WSOA 2VJ4A 4E3SA 4DTOA 3KD5E 4KHUA 1XMHE 4FVMA 4KHWA 3SQ4A 2ATQA 1XL3C 4EP9A 4KHYA 3NAEA 4JRQA 2JH8A 1MTYG 5H37A 3V7DB 4DU3A 3CFRA 4HCBA 4EYWA 4I6JB 4DTMA 4FJ9A 4J2DA 4KHQA 2B1EA 3TAEA 4ADOA 2DEBA 2OZSA 4FJLA 4RG8A 2JH9A 2FYOA 3SNNA 3TABA 1FZ1E 5IZ7A 3SQ0A 2OVRB 4AI6A 4AKIA 3RWUA 4FK4A 4ADNA 2P1MB 2MMBA 4DTPA 5IBKB 1FZ4E 3LDBA 1XMGE 3RMBA 4DTJA 2P5GA 3QEWA 2LF6A 2OYQA 3UIQA 1MMOG 3QERA 4FJHA 4FJMA 3QESA 4FJGA 4FK0A 3OGLB 1XVFE 4DTXA 3QEIA 1Q9YA 1NEXB 3C94A 2H4TA 4DTUA 2OVPB 2JPNA 3RMAA 4RL5A 3QEXA 4FJ5A 2OVQB 3CFPA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2PFV A;  2B7M A;  2PFT A;  4RL5 A;  2B1E A; 
#chains in the Genus database with same CATH topology
 2MW2 A;  4J2A A;  1MHY G;  3QEV A;  4M3X A;  1XVC E;  3NDK A;  1FZ7 E;  2HD0 A;  2P1O B;  3C6O B;  3E4Y A;  3SPY A;  4I9L A;  1IG9 A;  4FJ8 A;  3J2P A;  1LDK E;  4M42 A;  4M3Z A;  2P1Q B;  4FK2 A;  2JHA A;  2RCU A;  4RNG A;  3QEP A;  3NE6 A;  2JQT A;  4B08 A;  2K5S A;  2P5O A;  1FXX A;  1FZ3 E;  2P1N B;  2YB5 A;  4GAM C;  3SQ1 A;  1XMF E;  4FJI A;  3HP9 A;  4FJK A;  2P1P B;  4KHN A;  3RMC A;  3L0M A;  1IH7 A;  1Q9X A;  4DTN A;  1WAJ A;  2VIX A;  4KI4 A;  3LDS A;  5IRE A;  1P22 A;  3SJJ A;  4E4B A;  3HL8 A;  1FYZ E;  4X5N A;  4X5M A;  3HGL A;  4JRP A;  4M3W A;  3LZJ A;  1XU3 E;  2B7M A;  3SCX A;  3CFO A;  1XVB E;  1XVG E;  1FZ9 E;  1FZ8 E;  3HGK E;  3LD8 A;  1FZ2 E;  2MZW B;  3LZI A;  4JS5 A;  4KHS A;  2OZM A;  4I9Q A;  1FZI E;  4DU1 A;  4KI6 A;  3BVO A;  3TAF A;  4IT5 A;  4M3R A;  3J27 A;  3CQ8 A;  3TJY A;  4AKG A;  3C95 A;  2QXF A;  1XVD E;  4AKH A;  3TAG A;  1FZ5 E;  2E31 A;  2JHP A;  2E32 A;  2LF3 A;  3SVI A;  3MKS B;  4J2B A;  1WAF A;  2RKH A;  3SQ2 A;  3TL8 B;  2FW3 A;  2DTU A;  3RMD A;  4M3Y A;  4DTS A;  3OGK B;  2PFT A;  4EPH A;  3SPZ A;  4FJX A;  1N1C A;  4FJN A;  4M3U A;  1JW2 A;  4JS4 A;  3NCI A;  3SUN A;  2JHC A;  4FJJ A;  3C6P B;  4FJ7 A;  4QNC A;  4M3T A;  3N1E A;  3SI6 A;  1FZH E;  4HCC A;  1FS1 A;  1MHZ G;  1FZ0 E;  4DU4 A;  4M41 A;  3SUQ A;  1CLQ A;  4DTR A;  2PFV A;  3UO2 A;  3C6N B;  4QND A;  1FZ6 E;  4M45 A;  3QET A;  2VJ5 A;  3SUP A;  1XVE E;  3L8B A;  3SUO A;  3S9H A;  3KD1 E;  3L1N A;  3N1B A;  1XU5 E;  2DY4 A;  3L2O B;  2B8I A;  3QNN A;  4J2E A;  3K2O A;  3NHG A;  3E4W A;  3NGI A;  3QNO A;  3OGM B;  3WSO A;  2VJ4 A;  4E3S A;  4DTO A;  3KD5 E;  4KHU A;  1XMH E;  4FVM A;  4KHW A;  3SQ4 A;  1FPO A;  2ATQ A;  1XL3 C;  4EP9 A;  4KHY A;  3NAE A;  4JRQ A;  2JH8 A;  1MTY G;  5H37 A;  3V7D B;  4DU3 A;  3CFR A;  3UO3 A;  4HCB A;  4EYW A;  4I6J B;  4DTM A;  4FJ9 A;  4J2D A;  4KHQ A;  2B1E A;  3TAE A;  4ADO A;  2DEB A;  2OZS A;  4FJL A;  4RG8 A;  2JH9 A;  2FYO A;  3SNN A;  3TAB A;  1FZ1 E;  5IZ7 A;  3SQ0 A;  2OVR B;  4AI6 A;  4AKI A;  3RWU A;  4FK4 A;  4ADN A;  2P1M B;  2MMB A;  4DTP A;  5IBK B;  1FZ4 E;  3LDB A;  1XMG E;  3RMB A;  4ICG C;  4DTJ A;  2P5G A;  3QEW A;  2LF6 A;  2OYQ A;  3UIQ A;  1MMO G;  3QER A;  4FJH A;  4FJM A;  3QES A;  4FJG A;  4FK0 A;  3OGL B;  1XVF E;  4DTX A;  3QEI A;  1Q9Y A;  1NEX B;  3C94 A;  2H4T A;  4DTU A;  2OVP B;  2JPN A;  3RMA A;  4RL5 A;  3QEX A;  4FJ5 A;  2OVQ B;  3CFP A; 
#chains in the Genus database with same CATH homology
 4J2A A;  1MHY G;  3QEV A;  4M3X A;  1XVC E;  3NDK A;  1FZ7 E;  3C6O B;  2HD0 A;  2P1O B;  3E4Y A;  3SPY A;  4I9L A;  1IG9 A;  4FJ8 A;  3J2P A;  1LDK E;  4M42 A;  4M3Z A;  2P1Q B;  4FK2 A;  2JHA A;  2RCU A;  4RNG A;  3QEP A;  3NE6 A;  4B08 A;  2P5O A;  1FXX A;  1FZ3 E;  2P1N B;  2YB5 A;  4GAM C;  3SQ1 A;  1XMF E;  4FJI A;  3HP9 A;  4FJK A;  2P1P B;  4KHN A;  3RMC A;  3L0M A;  1IH7 A;  1Q9X A;  4DTN A;  1WAJ A;  2VIX A;  4KI4 A;  3LDS A;  5IRE A;  1P22 A;  3SJJ A;  4E4B A;  3HL8 A;  1FYZ E;  4X5N A;  4X5M A;  3HGL A;  4JRP A;  4M3W A;  3LZJ A;  1XU3 E;  2B7M A;  3SCX A;  3CFO A;  1XVB E;  1XVG E;  1FZ9 E;  1FZ8 E;  3HGK E;  3LD8 A;  1FZ2 E;  2MZW B;  3LZI A;  4JS5 A;  4KHS A;  2OZM A;  4I9Q A;  1FZI E;  4DU1 A;  4KI6 A;  3TAF A;  4M3R A;  3J27 A;  3CQ8 A;  3TJY A;  4AKG A;  3C95 A;  2QXF A;  1XVD E;  4AKH A;  3TAG A;  1FZ5 E;  2E31 A;  2JHP A;  2E32 A;  2LF3 A;  3SVI A;  3MKS B;  4J2B A;  1WAF A;  3SQ2 A;  3TL8 B;  2FW3 A;  2DTU A;  3RMD A;  4M3Y A;  4DTS A;  3OGK B;  2PFT A;  4EPH A;  3SPZ A;  4FJX A;  4FJN A;  4M3U A;  4JS4 A;  3NCI A;  3SUN A;  2JHC A;  4FJJ A;  3C6P B;  4FJ7 A;  4QNC A;  4M3T A;  3N1E A;  3SI6 A;  1FZH E;  4HCC A;  1FS1 A;  1MHZ G;  1FZ0 E;  4DU4 A;  4M41 A;  3SUQ A;  1CLQ A;  4DTR A;  2PFV A;  3C6N B;  4QND A;  1FZ6 E;  4M45 A;  3QET A;  2VJ5 A;  3SUP A;  1XVE E;  3L8B A;  3SUO A;  3S9H A;  3KD1 E;  3L1N A;  3N1B A;  1XU5 E;  2DY4 A;  3L2O B;  2B8I A;  3QNN A;  4J2E A;  3K2O A;  3NHG A;  3E4W A;  3NGI A;  3QNO A;  3OGM B;  3WSO A;  2VJ4 A;  4E3S A;  4DTO A;  3KD5 E;  4KHU A;  1XMH E;  4FVM A;  4KHW A;  3SQ4 A;  2ATQ A;  1XL3 C;  4EP9 A;  4KHY A;  3NAE A;  4JRQ A;  2JH8 A;  1MTY G;  5H37 A;  3V7D B;  4DU3 A;  3CFR A;  4HCB A;  4EYW A;  4I6J B;  4DTM A;  4FJ9 A;  4J2D A;  4KHQ A;  2B1E A;  3TAE A;  4ADO A;  2DEB A;  2OZS A;  4FJL A;  4RG8 A;  2JH9 A;  2FYO A;  3SNN A;  3TAB A;  1FZ1 E;  5IZ7 A;  3SQ0 A;  2OVR B;  4AI6 A;  4AKI A;  3RWU A;  4FK4 A;  4ADN A;  2P1M B;  2MMB A;  4DTP A;  5IBK B;  1FZ4 E;  3LDB A;  1XMG E;  3RMB A;  4DTJ A;  2P5G A;  3QEW A;  2LF6 A;  2OYQ A;  3UIQ A;  1MMO G;  3QER A;  4FJH A;  4FJM A;  3QES A;  4FJG A;  4FK0 A;  3OGL B;  1XVF E;  4DTX A;  3QEI A;  1Q9Y A;  1NEX B;  3C94 A;  2H4T A;  4DTU A;  2OVP B;  2JPN A;  3RMA A;  4RL5 A;  3QEX A;  4FJ5 A;  2OVQ B;  3CFP A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...