3N1EA

Vps54 c-terminal domain
Total Genus 56
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
56
sequence length
140
structure length
140
Chain Sequence
DQWSMLRHFDHITKDYHDHIAEISAKLVAIMDSLFDKLLSKYEVKAPVPSPCFRNICKQMTKMHEAIFDLLPEEQTQMLFLRINASYKLHLKKQLSHLNVINDGGPQNGLVTADVAFYTGNLQALKGLKDLDLNMAEIWE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structural basis for the wobbler mouse neurodegenerative disorder caused by mutation in the Vps54 subunit of the GARP complex.
pubmed doi rcsb
molecule tags Transport protein
source organism Mus musculus
molecule keywords Vacuolar protein sorting-associated protein 54
total genus 56
structure length 140
sequence length 140
chains with identical sequence B
ec nomenclature
pdb deposition date 2010-05-15
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1280.130 Mainly Alpha Up-down Bundle Monooxygenase Monooxygenase 3n1eA02
3N1BA 3N1EA
chains in the Genus database with same CATH superfamily
4J2DA 3L2OB 4FJNA 4FK0A 1FYZE 1FZ0E 1XVFE 3MKSB 4FJHA 4ADOA 3NAEA 1FZ6E 4QNCA 1MHZG 1FZIE 3SJJA 3LDSA 2DY4A 4FJGA 4KHUA 1XMHE 4I9LA 4M45A 2OVQB 3WSOA 2H4TA 4M3RA 4DTOA 4M3WA 1XMFE 1FZ3E 4DU4A 4FJ9A 3OGKB 2P1NB 3QNNA 4FJLA 3RWUA 4E4BA 1Q9YA 4M3YA 4IT5A 2OZSA 3HGLA 1XL3C 3L0MA 3LD8A 3NCIA 4I6JB 1XVGE 3LZIA 3LZJA 2JH8A 2K5SA 3HL8A 3LDBA 2OZMA 4X5NA 1XU3E 4M3UA 3TL8B 3CFPA 1IH7A 2DEBA 4EPHA 4QNDA 4AI6A 3N1EA 1WAJA 1XVDE 4DTJA 4M3XA 3TJYA 3RMAA 2MMBA 3N1BA 2P5OA 4M3ZA 3KD1E 4FJ5A 1FPOA 2B1EA 1NEXB 3K2OA 2PFTA 4M42A 2P1MB 3SPZA 2HD0A 2P5GA 4FJXA 3TABA 4JS4A 2FW3A 5IBKB 3NHGA 3QEVA 1FZHE 2JH9A 1MMOG 3J27A 3RMCA 3SQ1A 3OGLB 3C6OB 2LF6A 1XVBE 3KD5E 2JHCA 5IREA 4DU3A 2QXFA 1XVEE 2ATQA 2OYQA 4KHYA 2P1PB 4DTPA 1IG9A 4FJ7A 1FZ7E 3E4WA 3QEPA 3SUQA 4I9QA 4ADNA 1Q9XA 3C94A 3UO3A 4DTNA 3QEIA 4KI4A 2JQTA 3NGIA 2YB5A 1FZ5E 3E4YA 3SQ2A 1FXXA 1N1CA 1LDKE 3L8BA 2P1QB 3CQ8A 4HCCA 2VIXA 1CLQA 2RCUA 2P1OB 3QNOA 4AKIA 3TAEA 4KI6A 3SVIA 4KHQA 1FZ4E 4AKHA 2JHAA 2MZWB 1XVCE 3SNNA 1XMGE 4KHSA 3SPYA 4RL5A 4DU1A 3RMBA 4DTSA 4ICGC 4X5MA 2OVRB 2VJ4A 3C6PB 4J2BA 3TAGA 1FZ8E 2E32A 4GAMC 2OVPB 3L1NA 4B08A 3QEXA 3RMDA 1MHYG 4RG8A 1XU5E 3SI6A 4KHNA 4J2AA 4FJIA 3C6NB 1FZ1E 5IZ7A 3CFRA 4FJJA 4FK4A 4AKGA 2VJ5A 3C95A 3UIQA 2B7MA 3OGMB 3TAFA 2RKHA 3BVOA 3SQ4A 3V7DB 3UO2A 3NE6A 3NDKA 2E31A 3QETA 1MTYG 1FZ2E 2MW2A 1JW2A 4FJMA 4KHWA 2JHPA 5H37A 3SUOA 4FJKA 1FZ9E 3QESA 4EP9A 2FYOA 3HP9A 3QERA 3S9HA 2B8IA 4FVMA 3J2PA 2DTUA 4DTXA 2LF3A 4HCBA 3HGKE 3SUNA 4DTRA 4M3TA 1WAFA 2JPNA 4M41A 3SQ0A 4J2EA 1FS1A 4JRPA 3QEWA 4EYWA 4JS5A 4FJ8A 3CFOA 3SUPA 4FK2A 3SCXA 4RNGA 4DTUA 4E3SA 4JRQA 2PFVA 4DTMA 1P22A
chains in the Genus database with same CATH topology
4J2DA 3L2OB 4FJNA 4FK0A 1FYZE 1FZ0E 1XVFE 3MKSB 4FJHA 4ADOA 3NAEA 1FZ6E 4QNCA 1MHZG 1FZIE 3SJJA 3LDSA 2DY4A 4FJGA 4KHUA 1XMHE 4I9LA 4M45A 2OVQB 3WSOA 2H4TA 4M3RA 4DTOA 4M3WA 1XMFE 1FZ3E 4DU4A 4FJ9A 3OGKB 2P1NB 3QNNA 4FJLA 3RWUA 4E4BA 1Q9YA 4M3YA 2OZSA 3HGLA 1XL3C 3L0MA 3LD8A 3NCIA 4I6JB 1XVGE 3LZIA 3LZJA 2JH8A 3HL8A 3LDBA 4M3UA 2OZMA 4X5NA 1XU3E 3TL8B 3CFPA 1IH7A 2DEBA 4EPHA 4QNDA 4AI6A 3N1EA 1WAJA 1XVDE 4DTJA 4M3XA 3TJYA 3RMAA 2MMBA 3N1BA 2P5OA 4M3ZA 3KD1E 4FJ5A 2B1EA 1NEXB 3K2OA 2PFTA 4M42A 2P1MB 3SPZA 2HD0A 2P5GA 4FJXA 3TABA 4JS4A 2FW3A 5IBKB 3NHGA 3QEVA 1FZHE 2JH9A 1MMOG 3J27A 3RMCA 3SQ1A 3OGLB 3C6OB 2LF6A 1XVBE 3KD5E 2JHCA 5IREA 4DU3A 2QXFA 1XVEE 2ATQA 2OYQA 4KHYA 2P1PB 4DTPA 1IG9A 4FJ7A 1FZ7E 3E4WA 3QEPA 3SUQA 4I9QA 4ADNA 1Q9XA 3C94A 4DTNA 3QEIA 4KI4A 3NGIA 2YB5A 1FZ5E 3E4YA 3SQ2A 1FXXA 1LDKE 3L8BA 2P1QB 3CQ8A 4HCCA 2VIXA 1CLQA 2RCUA 2P1OB 3QNOA 4AKIA 3TAEA 4KI6A 3SVIA 4KHQA 1FZ4E 4AKHA 2JHAA 2MZWB 1XVCE 3SNNA 1XMGE 4KHSA 3SPYA 4RL5A 4DU1A 3RMBA 4DTSA 4X5MA 2OVRB 2VJ4A 3C6PB 4J2BA 3TAGA 1FZ8E 2E32A 4GAMC 2OVPB 3L1NA 4B08A 3QEXA 3RMDA 1MHYG 4RG8A 1XU5E 3SI6A 4KHNA 4J2AA 4FJIA 3C6NB 1FZ1E 5IZ7A 3CFRA 4FJJA 4FK4A 4AKGA 2VJ5A 3C95A 3UIQA 2B7MA 3OGMB 3TAFA 3SQ4A 3V7DB 3NE6A 3NDKA 2E31A 3QETA 1MTYG 1FZ2E 4FJMA 4KHWA 2JHPA 5H37A 3SUOA 4FJKA 1FZ9E 3QESA 4EP9A 2FYOA 3HP9A 3QERA 3S9HA 2B8IA 4FVMA 3J2PA 2DTUA 4DTXA 2LF3A 4HCBA 3HGKE 3SUNA 4DTRA 4M3TA 1WAFA 2JPNA 4M41A 3SQ0A 4J2EA 1FS1A 4JRPA 3QEWA 4EYWA 4JS5A 4FJ8A 3CFOA 3SUPA 4FK2A 3SCXA 4RNGA 4DTUA 4E3SA 4JRQA 2PFVA 4DTMA 1P22A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3N1B A;  3N1E A; 
#chains in the Genus database with same CATH topology
 4J2D A;  3L2O B;  4FJN A;  4FK0 A;  1FYZ E;  1FZ0 E;  1XVF E;  3MKS B;  4FJH A;  4ADO A;  3NAE A;  1FZ6 E;  4QNC A;  1MHZ G;  1FZI E;  3SJJ A;  3LDS A;  2DY4 A;  4FJG A;  4KHU A;  1XMH E;  4I9L A;  4M45 A;  2OVQ B;  3WSO A;  2H4T A;  4M3R A;  4DTO A;  4M3W A;  1XMF E;  1FZ3 E;  4DU4 A;  4FJ9 A;  3OGK B;  2P1N B;  3QNN A;  4FJL A;  3RWU A;  4E4B A;  1Q9Y A;  4M3Y A;  4IT5 A;  2OZS A;  3HGL A;  1XL3 C;  3L0M A;  3LD8 A;  3NCI A;  4I6J B;  1XVG E;  3LZI A;  3LZJ A;  2JH8 A;  2K5S A;  3HL8 A;  3LDB A;  2OZM A;  4X5N A;  1XU3 E;  4M3U A;  3TL8 B;  3CFP A;  1IH7 A;  2DEB A;  4EPH A;  4QND A;  4AI6 A;  3N1E A;  1WAJ A;  1XVD E;  4DTJ A;  4M3X A;  3TJY A;  3RMA A;  2MMB A;  3N1B A;  2P5O A;  4M3Z A;  3KD1 E;  4FJ5 A;  1FPO A;  2B1E A;  1NEX B;  3K2O A;  2PFT A;  4M42 A;  2P1M B;  3SPZ A;  2HD0 A;  2P5G A;  4FJX A;  3TAB A;  4JS4 A;  2FW3 A;  5IBK B;  3NHG A;  3QEV A;  1FZH E;  2JH9 A;  1MMO G;  3J27 A;  3RMC A;  3SQ1 A;  3OGL B;  3C6O B;  2LF6 A;  1XVB E;  3KD5 E;  2JHC A;  5IRE A;  4DU3 A;  2QXF A;  1XVE E;  2ATQ A;  2OYQ A;  4KHY A;  2P1P B;  4DTP A;  1IG9 A;  4FJ7 A;  1FZ7 E;  3E4W A;  3QEP A;  3SUQ A;  4I9Q A;  4ADN A;  1Q9X A;  3C94 A;  3UO3 A;  4DTN A;  3QEI A;  4KI4 A;  2JQT A;  3NGI A;  2YB5 A;  1FZ5 E;  3E4Y A;  3SQ2 A;  1FXX A;  1N1C A;  1LDK E;  3L8B A;  2P1Q B;  3CQ8 A;  4HCC A;  2VIX A;  1CLQ A;  2RCU A;  2P1O B;  3QNO A;  4AKI A;  3TAE A;  4KI6 A;  3SVI A;  4KHQ A;  1FZ4 E;  4AKH A;  2JHA A;  2MZW B;  1XVC E;  3SNN A;  1XMG E;  4KHS A;  3SPY A;  4RL5 A;  4DU1 A;  3RMB A;  4DTS A;  4ICG C;  4X5M A;  2OVR B;  2VJ4 A;  3C6P B;  4J2B A;  3TAG A;  1FZ8 E;  2E32 A;  4GAM C;  2OVP B;  3L1N A;  4B08 A;  3QEX A;  3RMD A;  1MHY G;  4RG8 A;  1XU5 E;  3SI6 A;  4KHN A;  4J2A A;  4FJI A;  3C6N B;  1FZ1 E;  5IZ7 A;  3CFR A;  4FJJ A;  4FK4 A;  4AKG A;  2VJ5 A;  3C95 A;  3UIQ A;  2B7M A;  3OGM B;  3TAF A;  2RKH A;  3BVO A;  3SQ4 A;  3V7D B;  3UO2 A;  3NE6 A;  3NDK A;  2E31 A;  3QET A;  1MTY G;  1FZ2 E;  2MW2 A;  1JW2 A;  4FJM A;  4KHW A;  2JHP A;  5H37 A;  3SUO A;  4FJK A;  1FZ9 E;  3QES A;  4EP9 A;  2FYO A;  3HP9 A;  3QER A;  3S9H A;  2B8I A;  4FVM A;  3J2P A;  2DTU A;  4DTX A;  2LF3 A;  4HCB A;  3HGK E;  3SUN A;  4DTR A;  4M3T A;  1WAF A;  2JPN A;  4M41 A;  3SQ0 A;  4J2E A;  1FS1 A;  4JRP A;  3QEW A;  4EYW A;  4JS5 A;  4FJ8 A;  3CFO A;  3SUP A;  4FK2 A;  3SCX A;  4RNG A;  4DTU A;  4E3S A;  4JRQ A;  2PFV A;  4DTM A;  1P22 A; 
#chains in the Genus database with same CATH homology
 4J2D A;  3L2O B;  4FJN A;  4FK0 A;  1FYZ E;  1FZ0 E;  1XVF E;  3MKS B;  4FJH A;  4ADO A;  3NAE A;  1FZ6 E;  4QNC A;  1MHZ G;  1FZI E;  3SJJ A;  3LDS A;  2DY4 A;  4FJG A;  4KHU A;  1XMH E;  4I9L A;  4M45 A;  2OVQ B;  3WSO A;  2H4T A;  4M3R A;  4DTO A;  4M3W A;  1XMF E;  1FZ3 E;  4DU4 A;  4FJ9 A;  3OGK B;  2P1N B;  3QNN A;  4FJL A;  3RWU A;  4E4B A;  1Q9Y A;  4M3Y A;  2OZS A;  3HGL A;  1XL3 C;  3L0M A;  3LD8 A;  3NCI A;  4I6J B;  1XVG E;  3LZI A;  3LZJ A;  2JH8 A;  3HL8 A;  3LDB A;  4M3U A;  2OZM A;  4X5N A;  1XU3 E;  3TL8 B;  3CFP A;  1IH7 A;  2DEB A;  4EPH A;  4QND A;  4AI6 A;  3N1E A;  1WAJ A;  1XVD E;  4DTJ A;  4M3X A;  3TJY A;  3RMA A;  2MMB A;  3N1B A;  2P5O A;  4M3Z A;  3KD1 E;  4FJ5 A;  2B1E A;  1NEX B;  3K2O A;  2PFT A;  4M42 A;  2P1M B;  3SPZ A;  2HD0 A;  2P5G A;  4FJX A;  3TAB A;  4JS4 A;  2FW3 A;  5IBK B;  3NHG A;  3QEV A;  1FZH E;  2JH9 A;  1MMO G;  3J27 A;  3RMC A;  3SQ1 A;  3OGL B;  3C6O B;  2LF6 A;  1XVB E;  3KD5 E;  2JHC A;  5IRE A;  4DU3 A;  2QXF A;  1XVE E;  2ATQ A;  2OYQ A;  4KHY A;  2P1P B;  4DTP A;  1IG9 A;  4FJ7 A;  1FZ7 E;  3E4W A;  3QEP A;  3SUQ A;  4I9Q A;  4ADN A;  1Q9X A;  3C94 A;  4DTN A;  3QEI A;  4KI4 A;  3NGI A;  2YB5 A;  1FZ5 E;  3E4Y A;  3SQ2 A;  1FXX A;  1LDK E;  3L8B A;  2P1Q B;  3CQ8 A;  4HCC A;  2VIX A;  1CLQ A;  2RCU A;  2P1O B;  3QNO A;  4AKI A;  3TAE A;  4KI6 A;  3SVI A;  4KHQ A;  1FZ4 E;  4AKH A;  2JHA A;  2MZW B;  1XVC E;  3SNN A;  1XMG E;  4KHS A;  3SPY A;  4RL5 A;  4DU1 A;  3RMB A;  4DTS A;  4X5M A;  2OVR B;  2VJ4 A;  3C6P B;  4J2B A;  3TAG A;  1FZ8 E;  2E32 A;  4GAM C;  2OVP B;  3L1N A;  4B08 A;  3QEX A;  3RMD A;  1MHY G;  4RG8 A;  1XU5 E;  3SI6 A;  4KHN A;  4J2A A;  4FJI A;  3C6N B;  1FZ1 E;  5IZ7 A;  3CFR A;  4FJJ A;  4FK4 A;  4AKG A;  2VJ5 A;  3C95 A;  3UIQ A;  2B7M A;  3OGM B;  3TAF A;  3SQ4 A;  3V7D B;  3NE6 A;  3NDK A;  2E31 A;  3QET A;  1MTY G;  1FZ2 E;  4FJM A;  4KHW A;  2JHP A;  5H37 A;  3SUO A;  4FJK A;  1FZ9 E;  3QES A;  4EP9 A;  2FYO A;  3HP9 A;  3QER A;  3S9H A;  2B8I A;  4FVM A;  3J2P A;  2DTU A;  4DTX A;  2LF3 A;  4HCB A;  3HGK E;  3SUN A;  4DTR A;  4M3T A;  1WAF A;  2JPN A;  4M41 A;  3SQ0 A;  4J2E A;  1FS1 A;  4JRP A;  3QEW A;  4EYW A;  4JS5 A;  4FJ8 A;  3CFO A;  3SUP A;  4FK2 A;  3SCX A;  4RNG A;  4DTU A;  4E3S A;  4JRQ A;  2PFV A;  4DTM A;  1P22 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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