3N1EA

Vps54 c-terminal domain
Total Genus 56
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
56
sequence length
140
structure length
140
Chain Sequence
DQWSMLRHFDHITKDYHDHIAEISAKLVAIMDSLFDKLLSKYEVKAPVPSPCFRNICKQMTKMHEAIFDLLPEEQTQMLFLRINASYKLHLKKQLSHLNVINDGGPQNGLVTADVAFYTGNLQALKGLKDLDLNMAEIWE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structural basis for the wobbler mouse neurodegenerative disorder caused by mutation in the Vps54 subunit of the GARP complex.
pubmed doi rcsb
molecule tags Transport protein
source organism Mus musculus
molecule keywords Vacuolar protein sorting-associated protein 54
total genus 56
structure length 140
sequence length 140
chains with identical sequence B
ec nomenclature
pdb deposition date 2010-05-15
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1280.130 Mainly Alpha Up-down Bundle Monooxygenase Monooxygenase 3n1eA02
3N1EA 3N1BA
chains in the Genus database with same CATH superfamily
2P1QB 4DTJA 2JHPA 5IZ7A 4IT5A 1WAFA 3N1BA 4M3RA 1FZ4E 2B8IA 4ADOA 3J2PA 2PFVA 2DEBA 3QEIA 3MKSB 1XVBE 2HD0A 4DTMA 4J2BA 4DTXA 4FJJA 5IBKB 1XU3E 3NAEA 2ATQA 4X5NA 4DTNA 2OYQA 3UIQA 1XVDE 3CQ8A 3SUQA 3NHGA 3QESA 1XMFE 1XVCE 3HL8A 2VIXA 1MHYG 3L0MA 2VJ5A 3C94A 3LZJA 4EYWA 3TABA 4FJKA 1XVEE 4X5MA 2RCUA 2P1PB 3QEWA 1IH7A 1FZ0E 1Q9YA 2P1NB 4QNDA 3L2OB 4RG8A 4J2EA 2JH9A 2MW2A 4DU3A 3UO2A 4KHYA 1JW2A 4KHNA 2RKHA 4DTUA 2PFTA 3QEVA 3RMCA 4QNCA 4DTSA 1MTYG 2P5OA 4KHUA 4E3SA 1WAJA 3SPYA 3SQ4A 1FZ6E 3NGIA 3HP9A 4M42A 4AI6A 3TL8B 2LF6A 2FYOA 3N1EA 3SQ1A 3C6NB 3OGKB 1FYZE 3HGKE 4ICGC 4JS4A 3TAGA 2JHAA 3QNNA 4J2AA 4JS5A 2OZMA 3OGLB 4DTRA 4FJNA 4FJIA 4KHWA 2K5SA 4DU1A 3SUNA 4J2DA 3BVOA 4RNGA 5H37A 1NEXB 1FXXA 1FZ9E 3KD5E 1XU5E 3SPZA 4M3ZA 4RL5A 3SQ2A 4GAMC 1FZ1E 1MMOG 4DU4A 2MMBA 2FW3A 2VJ4A 3SUPA 3RMAA 4HCBA 2JPNA 4FK0A 4KHSA 4M3TA 4DTPA 4DTOA 3SNNA 4FJ8A 2OVQB 2P1MB 1XL3C 3CFRA 4M3UA 4KI4A 2E32A 4E4BA 4JRQA 3RMDA 4FJGA 4M45A 2YB5A 3C95A 3KD1E 4FJLA 2QXFA 1XVGE 1FZ3E 3LDSA 3QETA 2P5GA 2DTUA 4AKHA 1XMHE 2JQTA 2OZSA 4KHQA 4FVMA 4I6JB 2JH8A 3J27A 4JRPA 3RMBA 1MHZG 2E31A 3LD8A 1FZ8E 4EP9A 3SJJA 2LF3A 3QEXA 1N1CA 3C6PB 1FZ5E 4FK4A 3CFPA 4FJHA 5IREA 1FZ2E 3TJYA 1FZ7E 3SUOA 4FJ9A 1CLQA 3QNOA 1FZIE 3SVIA 3OGMB 3TAEA 1FS1A 4AKIA 2B7MA 2JHCA 3CFOA 3TAFA 3V7DB 4M3XA 2B1EA 4I9LA 4M41A 3S9HA 1Q9XA 1XMGE 4FJ7A 4HCCA 4AKGA 1FPOA 1LDKE 4FJ5A 4M3WA 3NE6A 3NDKA 3L1NA 2DY4A 3E4YA 3UO3A 3E4WA 4FJXA 4I9QA 3SI6A 3SQ0A 3HGLA 4FK2A 2P1OB 2H4TA 3LZIA 3QEPA 4FJMA 4EPHA 4KI6A 3LDBA 1FZHE 1IG9A 3RWUA 4ADNA 3L8BA 4M3YA 2OVPB 1XVFE 2MZWB 3WSOA 3QERA 3NCIA 3K2OA 4B08A 1P22A 3SCXA 2OVRB 3C6OB
chains in the Genus database with same CATH topology
2P1QB 4DTJA 2JHPA 5IZ7A 1WAFA 3N1BA 4M3RA 1FZ4E 2B8IA 4ADOA 3J2PA 2PFVA 2DEBA 3QEIA 3MKSB 1XVBE 2HD0A 4DTMA 4J2BA 4DTXA 4FJJA 5IBKB 1XU3E 3NAEA 2ATQA 4X5NA 4DTNA 2OYQA 3UIQA 1XVDE 3CQ8A 3SUQA 3NHGA 3QESA 1XMFE 1XVCE 3HL8A 2VIXA 1MHYG 3L0MA 2VJ5A 3C94A 3LZJA 4EYWA 3TABA 4FJKA 1XVEE 4X5MA 2RCUA 2P1PB 3QEWA 1IH7A 1FZ0E 1Q9YA 2P1NB 4QNDA 3L2OB 4RG8A 4J2EA 2JH9A 4DU3A 4KHYA 4KHNA 4DTUA 2PFTA 3QEVA 3RMCA 4QNCA 4DTSA 1MTYG 2P5OA 4KHUA 4E3SA 1WAJA 3SPYA 3SQ4A 1FZ6E 3NGIA 3HP9A 4M42A 4AI6A 3TL8B 2LF6A 2FYOA 3N1EA 3SQ1A 3C6NB 3OGKB 1FYZE 3HGKE 4JS4A 3TAGA 2JHAA 3QNNA 4J2AA 4JS5A 2OZMA 3OGLB 4DTRA 4FJNA 4FJIA 4KHWA 4DU1A 4J2DA 3SUNA 5H37A 4RNGA 1NEXB 1FXXA 1FZ9E 3KD5E 1XU5E 3SPZA 4M3ZA 4RL5A 3SQ2A 4GAMC 1FZ1E 1MMOG 4DU4A 2MMBA 2FW3A 2VJ4A 3SUPA 3RMAA 4HCBA 2JPNA 4FK0A 4KHSA 4M3TA 4DTPA 4DTOA 3SNNA 4FJ8A 2OVQB 2P1MB 1XL3C 3CFRA 4M3UA 4KI4A 2E32A 4E4BA 4JRQA 3RMDA 4FJGA 4M45A 2YB5A 3C95A 3KD1E 4FJLA 2QXFA 1XVGE 1FZ3E 3LDSA 3QETA 2P5GA 2DTUA 4AKHA 1XMHE 2OZSA 4KHQA 4FVMA 4I6JB 2JH8A 3J27A 4JRPA 3RMBA 1MHZG 2E31A 3LD8A 1FZ8E 4EP9A 3SJJA 2LF3A 3QEXA 3C6PB 1FZ5E 4FK4A 3CFPA 4FJHA 5IREA 1FZ2E 3TJYA 1FZ7E 3SUOA 4FJ9A 1CLQA 3QNOA 1FZIE 3SVIA 3OGMB 3TAEA 1FS1A 4AKIA 2B7MA 2JHCA 3CFOA 3TAFA 3V7DB 4M3XA 2B1EA 4I9LA 4M41A 3S9HA 1Q9XA 1XMGE 4FJ7A 4HCCA 4AKGA 1LDKE 4FJ5A 4M3WA 3NE6A 3NDKA 3L1NA 2DY4A 3E4YA 3E4WA 4FJXA 4I9QA 3SI6A 3SQ0A 3HGLA 4FK2A 2P1OB 2H4TA 3LZIA 3QEPA 4FJMA 4EPHA 4KI6A 3LDBA 1FZHE 1IG9A 3RWUA 4ADNA 3L8BA 4M3YA 2OVPB 1XVFE 2MZWB 3WSOA 3QERA 3NCIA 3K2OA 4B08A 1P22A 3SCXA 2OVRB 3C6OB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3N1E A;  3N1B A; 
#chains in the Genus database with same CATH topology
 2P1Q B;  4DTJ A;  2JHP A;  5IZ7 A;  4IT5 A;  1WAF A;  3N1B A;  4M3R A;  1FZ4 E;  2B8I A;  4ADO A;  3J2P A;  2PFV A;  2DEB A;  3QEI A;  3MKS B;  1XVB E;  2HD0 A;  4DTM A;  4J2B A;  4DTX A;  4FJJ A;  5IBK B;  1XU3 E;  3NAE A;  2ATQ A;  4X5N A;  4DTN A;  2OYQ A;  3UIQ A;  1XVD E;  3CQ8 A;  3SUQ A;  3NHG A;  3QES A;  1XMF E;  1XVC E;  3HL8 A;  2VIX A;  1MHY G;  3L0M A;  2VJ5 A;  3C94 A;  3LZJ A;  4EYW A;  3TAB A;  4FJK A;  1XVE E;  4X5M A;  2RCU A;  2P1P B;  3QEW A;  1IH7 A;  1FZ0 E;  1Q9Y A;  2P1N B;  4QND A;  3L2O B;  4RG8 A;  4J2E A;  2JH9 A;  2MW2 A;  4DU3 A;  3UO2 A;  4KHY A;  1JW2 A;  4KHN A;  2RKH A;  4DTU A;  2PFT A;  3QEV A;  3RMC A;  4QNC A;  4DTS A;  1MTY G;  2P5O A;  4KHU A;  4E3S A;  1WAJ A;  3SPY A;  3SQ4 A;  1FZ6 E;  3NGI A;  3HP9 A;  4M42 A;  4AI6 A;  3TL8 B;  2LF6 A;  2FYO A;  3N1E A;  3SQ1 A;  3C6N B;  3OGK B;  1FYZ E;  3HGK E;  4ICG C;  4JS4 A;  3TAG A;  2JHA A;  3QNN A;  4J2A A;  4JS5 A;  2OZM A;  3OGL B;  4DTR A;  4FJN A;  4FJI A;  4KHW A;  2K5S A;  4DU1 A;  3SUN A;  4J2D A;  3BVO A;  4RNG A;  5H37 A;  1NEX B;  1FXX A;  1FZ9 E;  3KD5 E;  1XU5 E;  3SPZ A;  4M3Z A;  4RL5 A;  3SQ2 A;  4GAM C;  1FZ1 E;  1MMO G;  4DU4 A;  2MMB A;  2FW3 A;  2VJ4 A;  3SUP A;  3RMA A;  4HCB A;  2JPN A;  4FK0 A;  4KHS A;  4M3T A;  4DTP A;  4DTO A;  3SNN A;  4FJ8 A;  2OVQ B;  2P1M B;  1XL3 C;  3CFR A;  4M3U A;  4KI4 A;  2E32 A;  4E4B A;  4JRQ A;  3RMD A;  4FJG A;  4M45 A;  2YB5 A;  3C95 A;  3KD1 E;  4FJL A;  2QXF A;  1XVG E;  1FZ3 E;  3LDS A;  3QET A;  2P5G A;  2DTU A;  4AKH A;  1XMH E;  2JQT A;  2OZS A;  4KHQ A;  4FVM A;  4I6J B;  2JH8 A;  3J27 A;  4JRP A;  3RMB A;  1MHZ G;  2E31 A;  3LD8 A;  1FZ8 E;  4EP9 A;  3SJJ A;  2LF3 A;  3QEX A;  1N1C A;  3C6P B;  1FZ5 E;  4FK4 A;  3CFP A;  4FJH A;  5IRE A;  1FZ2 E;  3TJY A;  1FZ7 E;  3SUO A;  4FJ9 A;  1CLQ A;  3QNO A;  1FZI E;  3SVI A;  3OGM B;  3TAE A;  1FS1 A;  4AKI A;  2B7M A;  2JHC A;  3CFO A;  3TAF A;  3V7D B;  4M3X A;  2B1E A;  4I9L A;  4M41 A;  3S9H A;  1Q9X A;  1XMG E;  4FJ7 A;  4HCC A;  4AKG A;  1FPO A;  1LDK E;  4FJ5 A;  4M3W A;  3NE6 A;  3NDK A;  3L1N A;  2DY4 A;  3E4Y A;  3UO3 A;  3E4W A;  4FJX A;  4I9Q A;  3SI6 A;  3SQ0 A;  3HGL A;  4FK2 A;  2P1O B;  2H4T A;  3LZI A;  3QEP A;  4FJM A;  4EPH A;  4KI6 A;  3LDB A;  1FZH E;  1IG9 A;  3RWU A;  4ADN A;  3L8B A;  4M3Y A;  2OVP B;  1XVF E;  2MZW B;  3WSO A;  3QER A;  3NCI A;  3K2O A;  4B08 A;  1P22 A;  3SCX A;  2OVR B;  3C6O B; 
#chains in the Genus database with same CATH homology
 2P1Q B;  4DTJ A;  2JHP A;  5IZ7 A;  1WAF A;  3N1B A;  4M3R A;  1FZ4 E;  2B8I A;  4ADO A;  3J2P A;  2PFV A;  2DEB A;  3QEI A;  3MKS B;  1XVB E;  2HD0 A;  4DTM A;  4J2B A;  4DTX A;  4FJJ A;  5IBK B;  1XU3 E;  3NAE A;  2ATQ A;  4X5N A;  4DTN A;  2OYQ A;  3UIQ A;  1XVD E;  3CQ8 A;  3SUQ A;  3NHG A;  3QES A;  1XMF E;  1XVC E;  3HL8 A;  2VIX A;  1MHY G;  3L0M A;  2VJ5 A;  3C94 A;  3LZJ A;  4EYW A;  3TAB A;  4FJK A;  1XVE E;  4X5M A;  2RCU A;  2P1P B;  3QEW A;  1IH7 A;  1FZ0 E;  1Q9Y A;  2P1N B;  4QND A;  3L2O B;  4RG8 A;  4J2E A;  2JH9 A;  4DU3 A;  4KHY A;  4KHN A;  4DTU A;  2PFT A;  3QEV A;  3RMC A;  4QNC A;  4DTS A;  1MTY G;  2P5O A;  4KHU A;  4E3S A;  1WAJ A;  3SPY A;  3SQ4 A;  1FZ6 E;  3NGI A;  3HP9 A;  4M42 A;  4AI6 A;  3TL8 B;  2LF6 A;  2FYO A;  3N1E A;  3SQ1 A;  3C6N B;  3OGK B;  1FYZ E;  3HGK E;  4JS4 A;  3TAG A;  2JHA A;  3QNN A;  4J2A A;  4JS5 A;  2OZM A;  3OGL B;  4DTR A;  4FJN A;  4FJI A;  4KHW A;  4DU1 A;  4J2D A;  3SUN A;  5H37 A;  4RNG A;  1NEX B;  1FXX A;  1FZ9 E;  3KD5 E;  1XU5 E;  3SPZ A;  4M3Z A;  4RL5 A;  3SQ2 A;  4GAM C;  1FZ1 E;  1MMO G;  4DU4 A;  2MMB A;  2FW3 A;  2VJ4 A;  3SUP A;  3RMA A;  4HCB A;  2JPN A;  4FK0 A;  4KHS A;  4M3T A;  4DTP A;  4DTO A;  3SNN A;  4FJ8 A;  2OVQ B;  2P1M B;  1XL3 C;  3CFR A;  4M3U A;  4KI4 A;  2E32 A;  4E4B A;  4JRQ A;  3RMD A;  4FJG A;  4M45 A;  2YB5 A;  3C95 A;  3KD1 E;  4FJL A;  2QXF A;  1XVG E;  1FZ3 E;  3LDS A;  3QET A;  2P5G A;  2DTU A;  4AKH A;  1XMH E;  2OZS A;  4KHQ A;  4FVM A;  4I6J B;  2JH8 A;  3J27 A;  4JRP A;  3RMB A;  1MHZ G;  2E31 A;  3LD8 A;  1FZ8 E;  4EP9 A;  3SJJ A;  2LF3 A;  3QEX A;  3C6P B;  1FZ5 E;  4FK4 A;  3CFP A;  4FJH A;  5IRE A;  1FZ2 E;  3TJY A;  1FZ7 E;  3SUO A;  4FJ9 A;  1CLQ A;  3QNO A;  1FZI E;  3SVI A;  3OGM B;  3TAE A;  1FS1 A;  4AKI A;  2B7M A;  2JHC A;  3CFO A;  3TAF A;  3V7D B;  4M3X A;  2B1E A;  4I9L A;  4M41 A;  3S9H A;  1Q9X A;  1XMG E;  4FJ7 A;  4HCC A;  4AKG A;  1LDK E;  4FJ5 A;  4M3W A;  3NE6 A;  3NDK A;  3L1N A;  2DY4 A;  3E4Y A;  3E4W A;  4FJX A;  4I9Q A;  3SI6 A;  3SQ0 A;  3HGL A;  4FK2 A;  2P1O B;  2H4T A;  3LZI A;  3QEP A;  4FJM A;  4EPH A;  4KI6 A;  3LDB A;  1FZH E;  1IG9 A;  3RWU A;  4ADN A;  3L8B A;  4M3Y A;  2OVP B;  1XVF E;  2MZW B;  3WSO A;  3QER A;  3NCI A;  3K2O A;  4B08 A;  1P22 A;  3SCX A;  2OVR B;  3C6O B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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