1JFIC

Crystal structure of the nc2-tbp-dna ternary complex
Total Genus 46
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
46
sequence length
183
structure length
183
Chain Sequence
SHMSGIVPQLQNIVSTVNLGCKLDLKTIALRARNAEYNPKRFAAVIMRIREPRTTALIFSSGKMVCTGAKSEEQSRLAARKYARVVQKLGFPAKFLDFKIQNMVGSCDVKFPIRLEGLVLTHQQFSSYEPELFPGLIYRMIKPRIVLLIFVSGKVVLTGAKVRAEIYEAFENIYPILKGFRKT
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Crystal structure of negative cofactor 2 recognizing the TBP-DNA transcription complex.
pubmed doi rcsb
molecule tags Transcription/dna
source organism Homo sapiens
molecule keywords 5'-D(*TP*TP*GP*GP*CP*TP*AP*TP*AP*AP*AP*AP*GP*GP*GP*CP*TP*CP*
total genus 46
structure length 183
sequence length 183
ec nomenclature
pdb deposition date 2001-06-20

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
C PF00352 TBP Transcription factor TFIID (or TATA-binding protein, TBP)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.310.10 Alpha Beta 2-Layer Sandwich TATA-Binding Protein TATA-Binding Protein 1jfiC01
3.30.310.10 Alpha Beta 2-Layer Sandwich TATA-Binding Protein TATA-Binding Protein 1jfiC02
4RODB 1AISA 1QN7A 3VN5A 2D0AA 1QN4A 3H1ZA 1QNEA 1JFIC 1TGHA 1VOLB 1YTFA 1CDWA 2VJ0A 2G30A 1D3UA 5IYBP 1RM1A 1QNAA 1NVPA 1VOKA 1VTOA 1QNBA 1PZDA 2D0BA 3HS9A 1QN5A 3EIKA 1VTLE 1QNCA 5IYDP 1C9BB 1QN6A 1NH2A 4B0AA 1R4XA 1B9KA 1YTBA 2D0CA 1NGMA 1KYUA 1KYFA 1W80A 4WZSD 5IYCP 2IV9A 1KYDA 1QN9A 4ROEB 4PY5A 1QN3A 1KY6A 1MP9A 2MJ7A 1QN8A 1PCZA 1E42A 1KY7A 2IV8A 4ROCB 1TBPA 3OC3C 1QTSA 1QTPA 3OCIA 3ASMA 3HS8A 2Z8UA 1TBAB
chains in the Genus database with same CATH superfamily
1WQAA 5BMPA 3TE5A 1M3HA 1QN7A 3VN5A 1XSZA 1TGHA 1QNEA 3F0ZA 1DIZA 1RM1A 2NOHA 1VTOA 2YH5A 1P5GX 4C7PA 1QN5A 3I0WA 4D7RA 1QNCA 1YQRA 5JN5A 1C9BB 1QN6A 3CW7A 3EAYA 3KTUA 2HKPA 1P5DX 4BJUA 2D0CA 5AN4A 3D7QA 2NOZA 2FGTA 1W80A 1PCJX 2Y8LA 5IYCP 3PDKA 1N39A 1KYDA 1QN9A 2NOBA 4HJHA 4WX8A 1KY6A 2XHIA 1PCZA 2IV8A 1KY7A 1N3AA 2OOYA 1PVSA 2HZMA 2HL9A 1K35A 3OSEA 2QLVA 1UT4A 1PCMX 2V9JA 3H1ZA 1VOLB 1UL7A 1KFIA 5KL0A 1LWWA 1CDWA 1D3UA 4EJYA 2PWWA 1QNAA 1NVPA 1VOKA 1TUOA 4QG5A 2JHJA 3DPUA 1KO9A 2H5AX 3EIKA 3OLPA 4EAGA 3D4VA 1K2YX 3OH6A 1YQKA 1NH2A 2FKFA 1C4GA 4Q11A 1R4XA 3OH9A 1T6AA 4I8OA 3OSTA 1M3QA 2NVMA 1LWYA 3I3WA 2DKCA 3UW2A 1V5SA 3ULXA 1MP9A 1YQMA 3ENOC 1QN8A 3CWTA 2QR1A 1EBMA 3OGDA 1E42A 2NOLA 2NOIA 3DPTA 4WXAA 3OC3C 3CWSA 4EAIA 5F9CA 1LXTA 2Z8UA 4RODB 1AISA 3IH7A 1QN4A 3ENCA 1YTFA 2VJ0A 2FKMX 1QNBA 2D0BA 3HS9A 3CWAA 5BMNA 2JHNA 2Y8QA 2V92A 2H4LX 5HSHA 5IYDP 3PMGA 4MRQA 2NLVA 2QREA 2HL8A 1B9KA 2JPIA 1VKLA 3N89A 1HU0A 3RPJA 1Q9UA 1KYUA 1KYFA 1LWVA 2FUVA 4EJZA 1WJWA 1N3CA 1M5Q1 2R5XA 4ROEB 2NOEA 1QN3A 2MJ7A 4D7QA 4EALA 1MPGA 2V8QA 4ROCB 1TBPA 1QTSA 3ASMA 4EAJA 1EUVA 3OCIA 3I0XA 5IYBP 2OOXA 1J3MA 3TDHA 2JOIA 2D0AA 2YA3A 3NA5A 3BKQX 1JFIC 3CVTA 2QRCA 2G30A 2NWVA 4EAKA 1UT7A 2NOFA 1PZDA 3OSMA 1FN7A 1VTLE 2I5WA 2DKAA 2HZSA 4IL8A 5EPCA 4DULA 2LAEA 3KRMA 3RSMA 4B0AA 2EHBD 1YTBA 3F10A 1NGMA 1KFQA 4TPSA 3SNSA 1JDYA 2QRDA 4WZSD 1YQLA 2IV9A 1C47A 4CFFA 4PY5A 2O3OA 2F7LA 3CWUA 2Z0FA 2DKDA 3C04A 3CVSA 1QTPA 5JMVD 2MZ8A 3HS8A 2ZFDB 1TBAB 3T4NA
chains in the Genus database with same CATH topology
1M3HA 1QN7A 3VN5A 1TGHA 1QNEA 3F0ZA 1RM1A 2NOHA 1VTOA 2YH5A 1QN5A 3I0WA 1QNCA 1YQRA 1C9BB 1QN6A 3KTUA 2D0CA 5AN4A 2NOZA 2FGTA 1W80A 5IYCP 1N39A 1KYDA 1QN9A 2NOBA 1KY6A 2XHIA 1PCZA 2IV8A 1KY7A 1N3AA 2HZMA 1UT4A 3H1ZA 1VOLB 1LWWA 1CDWA 4EJYA 1D3UA 1QNAA 1NVPA 1VOKA 3DPUA 1KO9A 3EIKA 1YQKA 1NH2A 4Q11A 1R4XA 4I8OA 3OSTA 1M3QA 1LWYA 3ULXA 1MP9A 1YQMA 1QN8A 1EBMA 2NOLA 1E42A 2NOIA 3DPTA 3OC3C 2Z8UA 4RODB 1AISA 3IH7A 1QN4A 1YTFA 2VJ0A 1QNBA 2D0BA 3HS9A 5IYDP 1B9KA 3N89A 1HU0A 3RPJA 1KYUA 1KYFA 1LWVA 4EJZA 1N3CA 4ROEB 2NOEA 1QN3A 2MJ7A 4ROCB 1TBPA 1QTSA 3ASMA 3OCIA 3I0XA 5IYBP 2JOIA 2D0AA 1JFIC 2G30A 1UT7A 2NOFA 1PZDA 3OSMA 1FN7A 1VTLE 2I5WA 2HZSA 4DULA 2LAEA 3KRMA 4B0AA 1YTBA 3F10A 1NGMA 4TPSA 3SNSA 4WZSD 1YQLA 2IV9A 4PY5A 2O3OA 1QTPA 2MZ8A 3HS8A 1TBAB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4ROD B;  1AIS A;  1QN7 A;  3VN5 A;  2D0A A;  1QN4 A;  3H1Z A;  1QNE A;  1JFI C;  1TGH A;  1VOL B;  1YTF A;  1CDW A;  2VJ0 A;  2G30 A;  1D3U A;  5IYB P;  1RM1 A;  1QNA A;  1NVP A;  1VOK A;  1VTO A;  1QNB A;  1PZD A;  2D0B A;  3HS9 A;  1QN5 A;  3EIK A;  1VTL E;  1QNC A;  5IYD P;  1C9B B;  1QN6 A;  1NH2 A;  4B0A A;  1R4X A;  1B9K A;  1YTB A;  2D0C A;  1NGM A;  1KYU A;  1KYF A;  1W80 A;  4WZS D;  5IYC P;  2IV9 A;  1KYD A;  1QN9 A;  4ROE B;  4PY5 A;  1QN3 A;  1KY6 A;  1MP9 A;  2MJ7 A;  1QN8 A;  1PCZ A;  1E42 A;  1KY7 A;  2IV8 A;  4ROC B;  1TBP A;  3OC3 C;  1QTS A;  1QTP A;  3OCI A;  3ASM A;  3HS8 A;  2Z8U A;  1TBA B; 
#chains in the Genus database with same CATH topology
 1WQA A;  5BMP A;  3TE5 A;  1M3H A;  1QN7 A;  3VN5 A;  1XSZ A;  1TGH A;  1QNE A;  3F0Z A;  1DIZ A;  1RM1 A;  2NOH A;  1VTO A;  2YH5 A;  1P5G X;  4C7P A;  1QN5 A;  3I0W A;  4D7R A;  1QNC A;  1YQR A;  5JN5 A;  1C9B B;  1QN6 A;  3CW7 A;  3EAY A;  3KTU A;  2HKP A;  1P5D X;  4BJU A;  2D0C A;  5AN4 A;  3D7Q A;  2NOZ A;  2FGT A;  1W80 A;  1PCJ X;  2Y8L A;  5IYC P;  3PDK A;  1N39 A;  1KYD A;  1QN9 A;  2NOB A;  4HJH A;  4WX8 A;  1KY6 A;  2XHI A;  1PCZ A;  2IV8 A;  1KY7 A;  1N3A A;  2OOY A;  1PVS A;  2HZM A;  2HL9 A;  1K35 A;  3OSE A;  2QLV A;  1UT4 A;  1PCM X;  2V9J A;  3H1Z A;  1VOL B;  1UL7 A;  1KFI A;  5KL0 A;  1LWW A;  1CDW A;  1D3U A;  4EJY A;  2PWW A;  1QNA A;  1NVP A;  1VOK A;  1TUO A;  4QG5 A;  2JHJ A;  3DPU A;  1KO9 A;  2H5A X;  3EIK A;  3OLP A;  4EAG A;  3D4V A;  1K2Y X;  3OH6 A;  1YQK A;  1NH2 A;  2FKF A;  1C4G A;  4Q11 A;  1R4X A;  3OH9 A;  1T6A A;  4I8O A;  3OST A;  1M3Q A;  2NVM A;  1LWY A;  3I3W A;  2DKC A;  3UW2 A;  1V5S A;  3ULX A;  1MP9 A;  1YQM A;  3ENO C;  1QN8 A;  3CWT A;  2QR1 A;  1EBM A;  3OGD A;  1E42 A;  2NOL A;  2NOI A;  3DPT A;  4WXA A;  3OC3 C;  3CWS A;  4EAI A;  5F9C A;  1LXT A;  2Z8U A;  4ROD B;  1AIS A;  3IH7 A;  1QN4 A;  3ENC A;  1YTF A;  2VJ0 A;  2FKM X;  1QNB A;  2D0B A;  3HS9 A;  3CWA A;  5BMN A;  2JHN A;  2Y8Q A;  2V92 A;  2H4L X;  5HSH A;  5IYD P;  3PMG A;  4MRQ A;  2NLV A;  2QRE A;  2HL8 A;  1B9K A;  2JPI A;  1VKL A;  3N89 A;  1HU0 A;  3RPJ A;  1Q9U A;  1KYU A;  1KYF A;  1LWV A;  2FUV A;  4EJZ A;  1WJW A;  1N3C A;  1M5Q 1;  2R5X A;  4ROE B;  2NOE A;  1QN3 A;  2MJ7 A;  4D7Q A;  4EAL A;  1MPG A;  2V8Q A;  4ROC B;  1TBP A;  1QTS A;  3ASM A;  4EAJ A;  1EUV A;  3OCI A;  3I0X A;  5IYB P;  2OOX A;  1J3M A;  3TDH A;  2JOI A;  2D0A A;  2YA3 A;  3NA5 A;  3BKQ X;  1JFI C;  3CVT A;  2QRC A;  2G30 A;  2NWV A;  4EAK A;  1UT7 A;  2NOF A;  1PZD A;  3OSM A;  1FN7 A;  1VTL E;  2I5W A;  2DKA A;  2HZS A;  4IL8 A;  5EPC A;  4DUL A;  2LAE A;  3KRM A;  3RSM A;  4B0A A;  2EHB D;  1YTB A;  3F10 A;  1NGM A;  1KFQ A;  4TPS A;  3SNS A;  1JDY A;  2QRD A;  4WZS D;  1YQL A;  2IV9 A;  1C47 A;  4CFF A;  4PY5 A;  2O3O A;  2F7L A;  3CWU A;  2Z0F A;  2DKD A;  3C04 A;  3CVS A;  1QTP A;  5JMV D;  2MZ8 A;  3HS8 A;  2ZFD B;  1TBA B;  3T4N A; 
#chains in the Genus database with same CATH homology
 1M3H A;  1QN7 A;  3VN5 A;  1TGH A;  1QNE A;  3F0Z A;  1RM1 A;  2NOH A;  1VTO A;  2YH5 A;  1QN5 A;  3I0W A;  1QNC A;  1YQR A;  1C9B B;  1QN6 A;  3KTU A;  2D0C A;  5AN4 A;  2NOZ A;  2FGT A;  1W80 A;  5IYC P;  1N39 A;  1KYD A;  1QN9 A;  2NOB A;  1KY6 A;  2XHI A;  1PCZ A;  2IV8 A;  1KY7 A;  1N3A A;  2HZM A;  1UT4 A;  3H1Z A;  1VOL B;  1LWW A;  1CDW A;  4EJY A;  1D3U A;  1QNA A;  1NVP A;  1VOK A;  3DPU A;  1KO9 A;  3EIK A;  1YQK A;  1NH2 A;  4Q11 A;  1R4X A;  4I8O A;  3OST A;  1M3Q A;  1LWY A;  3ULX A;  1MP9 A;  1YQM A;  1QN8 A;  1EBM A;  2NOL A;  1E42 A;  2NOI A;  3DPT A;  3OC3 C;  2Z8U A;  4ROD B;  1AIS A;  3IH7 A;  1QN4 A;  1YTF A;  2VJ0 A;  1QNB A;  2D0B A;  3HS9 A;  5IYD P;  1B9K A;  3N89 A;  1HU0 A;  3RPJ A;  1KYU A;  1KYF A;  1LWV A;  4EJZ A;  1N3C A;  4ROE B;  2NOE A;  1QN3 A;  2MJ7 A;  4ROC B;  1TBP A;  1QTS A;  3ASM A;  3OCI A;  3I0X A;  5IYB P;  2JOI A;  2D0A A;  1JFI C;  2G30 A;  1UT7 A;  2NOF A;  1PZD A;  3OSM A;  1FN7 A;  1VTL E;  2I5W A;  2HZS A;  4DUL A;  2LAE A;  3KRM A;  4B0A A;  1YTB A;  3F10 A;  1NGM A;  4TPS A;  3SNS A;  4WZS D;  1YQL A;  2IV9 A;  4PY5 A;  2O3O A;  1QTP A;  2MZ8 A;  3HS8 A;  1TBA B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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