3NA5A

Crystal structure of a bacterial phosphoglucomutase, an enzyme important in the virulence of several human pathogens.
Total Genus 183
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
183
sequence length
545
structure length
544
Chain Sequence
AIHNRAGQPAQQSDLINVAQLTAQYYVLKPEAGNAEHAVKFGTSGHRGSAGRHSFNEPHILAIAQAIAEERAKNGITGPCYVGKDTHALSEPAFISVLEVLAANGVDVIVQENNGFTPTPAVSNAILVHNKKGGPLADGIVITPSHNPPEDGGIKYNPPNGGPADTNVTKVVEDRANALLAGGLQGVKRISLDAAMASGHVKAVDLVQPFVEGLADIVDMAAIQKAGLTLGVDPLGGSGIEYWKRIAEHYKLNLTLVNDQVDQTFRFMHLDKDGAIRMDCSSEAMAGLLALRDKFDLAFANDPDYDRHGIVTPAGLMNPNHYLAVAINYLFQHRPLWGKDVAVGKTLVSSAMIDRVVNDLGRKLVEVPVGFKWFVDGLFDGSFGFGGEESAGASFLRFDGTPWSTDKDGIIMCLLAAEITAVTGKNPQEHYNELAARFGAPSYNRLQASATSAQKAALSKLSPEMVSASTLAGDPITARLTAAPGNGASIGGLKVMTDNGWFAARPSGTEDAYKIYCESFLGEEHRKQIEKEAVEIVSEVLKNA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule tags Isomerase
molecule keywords Phosphoglucomutase
publication title Crystal structure of a bacterial phosphoglucomutase, an enzyme involved in the virulence of multiple human pathogens.
pubmed doi rcsb
source organism Salmonella enterica subsp. enterica serovar typhimurium
total genus 183
structure length 544
sequence length 545
chains with identical sequence B
ec nomenclature ec 5.4.2.2: Phosphoglucomutase (alpha-D-glucose-1,6-bisphosphate-dependent).
pdb deposition date 2010-06-01

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00408 PGM_PMM_IV Phosphoglucomutase/phosphomannomutase, C-terminal domain
A PF02878 PGM_PMM_I Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I
A PF02879 PGM_PMM_II Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II
A PF02880 PGM_PMM_III Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.310.50 Alpha Beta 2-Layer Sandwich TATA-Binding Protein Alpha-D-phosphohexomutase, C-terminal domain 3na5A04
3.40.120.10 Alpha Beta 3-Layer(aba) Sandwich Alpha-D-Glucose-1,6-Bisphosphate; Chain A, domain 3 Alpha-D-Glucose-1,6-Bisphosphate, subunit A, domain 3 3na5A03
3.40.120.10 Alpha Beta 3-Layer(aba) Sandwich Alpha-D-Glucose-1,6-Bisphosphate; Chain A, domain 3 Alpha-D-Glucose-1,6-Bisphosphate, subunit A, domain 3 3na5A02
3.40.120.10 Alpha Beta 3-Layer(aba) Sandwich Alpha-D-Glucose-1,6-Bisphosphate; Chain A, domain 3 Alpha-D-Glucose-1,6-Bisphosphate, subunit A, domain 3 3na5A01
1VKLA 1WQAA 5F9CA 3ENOC 5JMVD 1C47A 2DKCA 2FKMX 4BJUA 1PCJX 1LXTA 2Z0FA 3I3WA 3ENCA 3RSMA 5HSHA 1P5GX 5BMNA 4QG5A 3BKQX 3OLPA 3UW2A 2EHPA 3NA5A 2H4LX 1C4GA 4HJHA 1KFQA 2DKAA 4IL8A 1JDYA 1K35A 5KL0A 2FKFA 3C04A 4WX8A 5EPCA 2EIUA 1PCMX 4MRQA 2JPIA 1P5DX 1TUOA 4WXAA 3PDKA 1WJWA 2DKDA 5JN5A 1K2YX 2F7LA 2H5AX 2FUVA 1KFIA 3PMGA 5BMPA
chains in the Genus database with same CATH superfamily
2R5XA 1WQAA 5F9CA 1UL7A 3OSMA 2DKCA 1MPGA 3ULXA 2NOFA 1LXTA 3ENCA 3UW2A 1LWYA 1UT4A 2V8QA 1TBPA 1FN7A 2NOZA 3OC3C 2QREA 4EAGA 5IYDP 1KYDA 4HJHA 1B9KA 2DKAA 1YTBA 1QN5A 2XHIA 1QN6A 1VOKA 1PZDA 1NGMA 2O3OA 1M3HA 2EIUA 3D7QA 1YQLA 3CVTA 1TUOA 4WXAA 2Y8LA 4DULA 4I8OA 2NWVA 3VN5A 2HL8A 2FUVA 4IL8A 1LWVA 3N89A 3PMGA 5BMPA 3CWAA 3IH7A 4RODB 1QNCA 2NOLA 2NOIA 4BJUA 1QN3A 1MP9A 2Z0FA 3RSMA 5HSHA 1HU0A 2YA3A 1P5GX 1C9BB 4QG5A 3BKQX 1KYFA 4D7QA 1KY6A 1C4GA 2D0AA 1JFIC 2PWWA 1M5Q1 1UT7A 1YQRA 1N3AA 3OH6A 4CFFA 1K35A 5KL0A 2NVMA 1QN9A 2EHBD 2Z8UA 5IYCP 3D4VA 1QN7A 3OSTA 2JPIA 2D0CA 2NOBA 2VJ0A 5AN4A 1EBMA 2DKDA 3HS8A 2FGTA 1K2YX 2F7LA 2QRCA 3DPTA 4EAJA 1QN8A 1VKLA 1LWWA 2ZFDB 1QNEA 3SNSA 3DPUA 3ASMA 1PVSA 2FKMX 1VTOA 2G30A 4EJZA 3OCIA 2OOXA 2YH5A 1KYUA 2EHPA 3OLPA 1NVPA 1QNBA 4PY5A 1R4XA 4B0AA 1V5SA 3KTUA 2H4LX 4EALA 2MJ7A 2JHJA 4ROEB 2LAEA 4Q11A 1EUVA 1JDYA 1QTSA 3OSEA 4EAKA 1D3UA 3CWSA 2NOHA 2Y8QA 3OH9A 1N3CA 3CW7A 1PCMX 1Q9UA 2NOEA 1P5DX 1TBAB 2IV9A 2HKPA 3TE5A 5JN5A 1YQKA 3HS9A 1AISA 1QN4A 3CVSA 1KFIA 1XSZA 5JMVD 1DIZA 3H1ZA 3ENOC 1C47A 4EJYA 2NLVA 3I0WA 1KO9A 1TGHA 1PCJX 3EAYA 2IV8A 2QLVA 3I3WA 3F0ZA 1KY7A 1T6AA 3T4NA 5BMNA 3OGDA 3CWUA 3I0XA 1CDWA 3EIKA 2HL9A 2D0BA 2V9JA 1PCZA 1YQMA 3CWTA 3NA5A 1QTPA 1E42A 2QR1A 1M3QA 4ROCB 1N39A 3F10A 1KFQA 4C7PA 4TPSA 4D7RA 4WZSD 1YTFA 2OOYA 2V92A 2HZMA 5IYBP 2JHNA 4EAIA 2FKFA 1NH2A 2I5WA 2MZ8A 1VOLB 3C04A 2HZSA 4WX8A 5EPCA 3RPJA 4MRQA 1W80A 3TDHA 3PDKA 1WJWA 3KRMA 1VTLE 2H5AX 1QNAA 2QRDA 2JOIA 1J3MA 1RM1A
chains in the Genus database with same CATH topology
1VKLA 1WQAA 5F9CA 3ENOC 5JMVD 1C47A 2DKCA 2FKMX 4BJUA 1PCJX 1LXTA 2Z0FA 3I3WA 3ENCA 3RSMA 5HSHA 1P5GX 5BMNA 4QG5A 3BKQX 3OLPA 3UW2A 2EHPA 3NA5A 2H4LX 1C4GA 4HJHA 1KFQA 2DKAA 4IL8A 1JDYA 1K35A 5KL0A 2FKFA 3C04A 4WX8A 5EPCA 2EIUA 1PCMX 4MRQA 2JPIA 1P5DX 1TUOA 4WXAA 3PDKA 1WJWA 2DKDA 5JN5A 1K2YX 2F7LA 2H5AX 2FUVA 1KFIA 3PMGA 5BMPA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1VKL A;  1WQA A;  5F9C A;  3ENO C;  5JMV D;  1C47 A;  2DKC A;  2FKM X;  4BJU A;  1PCJ X;  1LXT A;  2Z0F A;  3I3W A;  3ENC A;  3RSM A;  5HSH A;  1P5G X;  5BMN A;  4QG5 A;  3BKQ X;  3OLP A;  3UW2 A;  2EHP A;  3NA5 A;  2H4L X;  1C4G A;  4HJH A;  1KFQ A;  2DKA A;  4IL8 A;  1JDY A;  1K35 A;  5KL0 A;  2FKF A;  3C04 A;  4WX8 A;  5EPC A;  2EIU A;  1PCM X;  4MRQ A;  2JPI A;  1P5D X;  1TUO A;  4WXA A;  3PDK A;  1WJW A;  2DKD A;  5JN5 A;  1K2Y X;  2F7L A;  2H5A X;  2FUV A;  1KFI A;  3PMG A;  5BMP A; 
#chains in the Genus database with same CATH topology
 2R5X A;  1WQA A;  5F9C A;  1UL7 A;  3OSM A;  2DKC A;  1MPG A;  3ULX A;  2NOF A;  1LXT A;  3ENC A;  3UW2 A;  1LWY A;  1UT4 A;  2V8Q A;  1TBP A;  1FN7 A;  2NOZ A;  3OC3 C;  2QRE A;  4EAG A;  5IYD P;  1KYD A;  4HJH A;  1B9K A;  2DKA A;  1YTB A;  1QN5 A;  2XHI A;  1QN6 A;  1VOK A;  1PZD A;  1NGM A;  2O3O A;  1M3H A;  2EIU A;  3D7Q A;  1YQL A;  3CVT A;  1TUO A;  4WXA A;  2Y8L A;  4DUL A;  4I8O A;  2NWV A;  3VN5 A;  2HL8 A;  2FUV A;  4IL8 A;  1LWV A;  3N89 A;  3PMG A;  5BMP A;  3CWA A;  3IH7 A;  4ROD B;  1QNC A;  2NOL A;  2NOI A;  4BJU A;  1QN3 A;  1MP9 A;  2Z0F A;  3RSM A;  5HSH A;  1HU0 A;  2YA3 A;  1P5G X;  1C9B B;  4QG5 A;  3BKQ X;  1KYF A;  4D7Q A;  1KY6 A;  1C4G A;  2D0A A;  1JFI C;  2PWW A;  1M5Q 1;  1UT7 A;  1YQR A;  1N3A A;  3OH6 A;  4CFF A;  1K35 A;  5KL0 A;  2NVM A;  1QN9 A;  2EHB D;  2Z8U A;  5IYC P;  3D4V A;  1QN7 A;  3OST A;  2JPI A;  2D0C A;  2NOB A;  2VJ0 A;  5AN4 A;  1EBM A;  2DKD A;  3HS8 A;  2FGT A;  1K2Y X;  2F7L A;  2QRC A;  3DPT A;  4EAJ A;  1QN8 A;  1VKL A;  1LWW A;  2ZFD B;  1QNE A;  3SNS A;  3DPU A;  3ASM A;  1PVS A;  2FKM X;  1VTO A;  2G30 A;  4EJZ A;  3OCI A;  2OOX A;  2YH5 A;  1KYU A;  2EHP A;  3OLP A;  1NVP A;  1QNB A;  4PY5 A;  1R4X A;  4B0A A;  1V5S A;  3KTU A;  2H4L X;  4EAL A;  2MJ7 A;  2JHJ A;  4ROE B;  2LAE A;  4Q11 A;  1EUV A;  1JDY A;  1QTS A;  3OSE A;  4EAK A;  1D3U A;  3CWS A;  2NOH A;  2Y8Q A;  3OH9 A;  1N3C A;  3CW7 A;  1PCM X;  1Q9U A;  2NOE A;  1P5D X;  1TBA B;  2IV9 A;  2HKP A;  3TE5 A;  5JN5 A;  1YQK A;  3HS9 A;  1AIS A;  1QN4 A;  3CVS A;  1KFI A;  1XSZ A;  5JMV D;  1DIZ A;  3H1Z A;  3ENO C;  1C47 A;  4EJY A;  2NLV A;  3I0W A;  1KO9 A;  1TGH A;  1PCJ X;  3EAY A;  2IV8 A;  2QLV A;  3I3W A;  3F0Z A;  1KY7 A;  1T6A A;  3T4N A;  5BMN A;  3OGD A;  3CWU A;  3I0X A;  1CDW A;  3EIK A;  2HL9 A;  2D0B A;  2V9J A;  1PCZ A;  1YQM A;  3CWT A;  3NA5 A;  1QTP A;  1E42 A;  2QR1 A;  1M3Q A;  4ROC B;  1N39 A;  3F10 A;  1KFQ A;  4C7P A;  4TPS A;  4D7R A;  4WZS D;  1YTF A;  2OOY A;  2V92 A;  2HZM A;  5IYB P;  2JHN A;  4EAI A;  2FKF A;  1NH2 A;  2I5W A;  2MZ8 A;  1VOL B;  3C04 A;  2HZS A;  4WX8 A;  5EPC A;  3RPJ A;  4MRQ A;  1W80 A;  3TDH A;  3PDK A;  1WJW A;  3KRM A;  1VTL E;  2H5A X;  1QNA A;  2QRD A;  2JOI A;  1J3M A;  1RM1 A; 
#chains in the Genus database with same CATH homology
 1VKL A;  1WQA A;  5F9C A;  3ENO C;  5JMV D;  1C47 A;  2DKC A;  2FKM X;  4BJU A;  1PCJ X;  1LXT A;  2Z0F A;  3I3W A;  3ENC A;  3RSM A;  5HSH A;  1P5G X;  5BMN A;  4QG5 A;  3BKQ X;  3OLP A;  3UW2 A;  2EHP A;  3NA5 A;  2H4L X;  1C4G A;  4HJH A;  1KFQ A;  2DKA A;  4IL8 A;  1JDY A;  1K35 A;  5KL0 A;  2FKF A;  3C04 A;  4WX8 A;  5EPC A;  2EIU A;  1PCM X;  4MRQ A;  2JPI A;  1P5D X;  1TUO A;  4WXA A;  3PDK A;  1WJW A;  2DKD A;  5JN5 A;  1K2Y X;  2F7L A;  2H5A X;  2FUV A;  1KFI A;  3PMG A;  5BMP A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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