4MRQA

Crystal structure of wild-type unphosphorylated pmm/pgm
Total Genus 168
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
168
sequence length
455
structure length
455
Chain Sequence
LPASIFRAYDIRGVVGDTLTAETAYWIGRAIGSESLARGEPCVAVGRDGRLSGPELVKQLIQGLVDCGCQVSDVGMVPTPVLYYAANVLEGKSGVMLTGSHNPPDYNGFKIVVAGETLANEQIQALRERIEKNDLASGVGSVEQVDILPRYFKQIRDDIAMAKPMKVVVDCGNGVAGVIAPQLIEALGCSVIPLYCEVDGNFPNHHPDPGKPENLKDLIAKVKAENADLGLAFDGDGDRVGVVTNTGTIIYPDRLLMLFAKDVVSRNPGADIIFDVKCTRRLIALISGYGGRPVMWKTGHSLIKKKMKETGALLAGEMSGHVFFKERWFGFDDGIYSAARLLEILSQDQRDSEHVFSAFPSDISTPEINITVTEDSKFAIIEALQRDAQWGEGNITTLDGVRVDYPKGWGLVRASNTTPVLVLRFEADTEEELERIKTVFRNQLKAVDSSLPVPF
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule keywords Phosphomannomutase/phosphoglucomutase
publication title Promotion of enzyme flexibility by dephosphorylation and coupling to the catalytic mechanism of a phosphohexomutase.
pubmed doi rcsb
source organism Pseudomonas aeruginosa
molecule tags Isomerase
total genus 168
structure length 455
sequence length 455
ec nomenclature ec 5.4.2.2: Phosphoglucomutase (alpha-D-glucose-1,6-bisphosphate-dependent).
pdb deposition date 2013-09-17

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00408 PGM_PMM_IV Phosphoglucomutase/phosphomannomutase, C-terminal domain
A PF02878 PGM_PMM_I Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I
A PF02879 PGM_PMM_II Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II
A PF02880 PGM_PMM_III Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.310.50 Alpha Beta 2-Layer Sandwich TATA-Binding Protein Alpha-D-phosphohexomutase, C-terminal domain 4mrqA04
3.40.120.10 Alpha Beta 3-Layer(aba) Sandwich Alpha-D-Glucose-1,6-Bisphosphate; Chain A, domain 3 Alpha-D-Glucose-1,6-Bisphosphate, subunit A, domain 3 4mrqA03
3.40.120.10 Alpha Beta 3-Layer(aba) Sandwich Alpha-D-Glucose-1,6-Bisphosphate; Chain A, domain 3 Alpha-D-Glucose-1,6-Bisphosphate, subunit A, domain 3 4mrqA01
3.40.120.10 Alpha Beta 3-Layer(aba) Sandwich Alpha-D-Glucose-1,6-Bisphosphate; Chain A, domain 3 Alpha-D-Glucose-1,6-Bisphosphate, subunit A, domain 3 4mrqA02
2H4LX 4HJHA 2DKCA 1WQAA 5F9CA 2EIUA 3NA5A 2DKAA 3PDKA 1PCJX 5KL0A 1KFIA 4MRQA 2F7LA 1LXTA 2JPIA 1K2YX 2H5AX 3RSMA 1VKLA 5BMPA 5BMNA 3BKQX 1JDYA 2FKMX 1WJWA 3ENOC 1P5GX 5JN5A 1P5DX 4QG5A 3C04A 4WXAA 3OLPA 5EPCA 3ENCA 3I3WA 3UW2A 1C4GA 4WX8A 4BJUA 1C47A 5HSHA 1PCMX 2DKDA 2Z0FA 2EHPA 4IL8A 1TUOA 2FKFA 3PMGA 1K35A 5JMVD 2FUVA 1KFQA
chains in the Genus database with same CATH superfamily
1UT7A 2O3OA 2DKCA 2R5XA 4HJHA 1WQAA 4EAGA 4EJYA 3NA5A 3KRMA 1MPGA 3RPJA 1JDYA 2FKMX 1N3CA 2NOLA 4B0AA 1P5GX 1B9KA 3SNSA 1YQLA 2MJ7A 2V9JA 2JHJA 1QNEA 3DPUA 3HS8A 1UT4A 2QRDA 1EBMA 3D4VA 2PWWA 2NOIA 1XSZA 2YA3A 1KY7A 3ASMA 1YQKA 4C7PA 2NOZA 1NVPA 5AN4A 1QN5A 2VJ0A 3I0WA 2HL8A 4EJZA 2MZ8A 1T6AA 3D7QA 3OSMA 5F9CA 1LWVA 1KO9A 2D0BA 1PCJX 2D0CA 3OCIA 3CVSA 1LWYA 2D0AA 5IYCP 4MRQA 1QN6A 2JPIA 1K2YX 1LWWA 1QNCA 1VOLB 1QN7A 1TBPA 1WJWA 2ZFDB 1P5DX 3N89A 1QN4A 2Y8LA 3C04A 3EIKA 4WXAA 3I0XA 1W80A 5EPCA 1FN7A 3ENCA 1VTOA 4D7QA 1JFIC 2Z8UA 4TPSA 1UL7A 1QTPA 3UW2A 4EAKA 4BJUA 4ROEB 1C47A 2EHBD 2G30A 1KYUA 2IV8A 2DKDA 2EHPA 1J3MA 3IH7A 2QREA 4EAJA 3PMGA 2HZMA 1C4GA 2NOEA 1M5Q1 2HZSA 4EALA 2EIUA 1MP9A 3CWAA 1D3UA 1KY6A 1NGMA 1AISA 1QN8A 1KFIA 4WZSD 3DPTA 1KYDA 2V8QA 4CFFA 2F7LA 2NWVA 2QR1A 2H5AX 3RSMA 1VKLA 5BMPA 5IYBP 3OGDA 3BKQX 1RM1A 1N39A 2IV9A 2OOXA 3ENOC 3H1ZA 2JHNA 2LAEA 1Q9UA 1YTFA 3OLPA 2YH5A 4RODB 4EAIA 3I3WA 3F10A 4DULA 4PY5A 3OSEA 1V5SA 2HL9A 1N3AA 1M3QA 5HSHA 1TGHA 2NOFA 2XHIA 1YTBA 1VOKA 1PCMX 3CWSA 2Z0FA 2OOYA 3CWUA 4IL8A 4Q11A 3OH6A 2I5WA 2NOBA 1K35A 5JMVD 2FUVA 1KFQA 1VTLE 3CW7A 5IYDP 1PVSA 2H4LX 1R4XA 1YQRA 1QNAA 5KL0A 2DKAA 3PDKA 1QNBA 3OH9A 1PZDA 3VN5A 1QTSA 1CDWA 1KYFA 1LXTA 3KTUA 5BMNA 2NVMA 2NOHA 3HS9A 1NH2A 3ULXA 3T4NA 5JN5A 3EAYA 4I8OA 2QRCA 1C9BB 4QG5A 1E42A 2V92A 3OSTA 1PCZA 3CWTA 2Y8QA 1QN9A 1TBAB 1DIZA 3CVTA 1QN3A 4D7RA 1M3HA 4WX8A 2QLVA 3F0ZA 2JOIA 3OC3C 3TDHA 1YQMA 2NLVA 4ROCB 1HU0A 3TE5A 2FKFA 2FGTA 2HKPA 1TUOA 1EUVA
chains in the Genus database with same CATH topology
2H4LX 4HJHA 2DKCA 1WQAA 5F9CA 2EIUA 3NA5A 2DKAA 3PDKA 1PCJX 5KL0A 1KFIA 4MRQA 2F7LA 1LXTA 2JPIA 1K2YX 2H5AX 3RSMA 1VKLA 5BMPA 5BMNA 3BKQX 1JDYA 2FKMX 1WJWA 3ENOC 1P5GX 5JN5A 1P5DX 4QG5A 3C04A 4WXAA 3OLPA 5EPCA 3ENCA 3I3WA 3UW2A 1C4GA 4WX8A 4BJUA 1C47A 5HSHA 1PCMX 2DKDA 2Z0FA 2EHPA 4IL8A 1TUOA 2FKFA 3PMGA 1K35A 5JMVD 2FUVA 1KFQA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2H4L X;  4HJH A;  2DKC A;  1WQA A;  5F9C A;  2EIU A;  3NA5 A;  2DKA A;  3PDK A;  1PCJ X;  5KL0 A;  1KFI A;  4MRQ A;  2F7L A;  1LXT A;  2JPI A;  1K2Y X;  2H5A X;  3RSM A;  1VKL A;  5BMP A;  5BMN A;  3BKQ X;  1JDY A;  2FKM X;  1WJW A;  3ENO C;  1P5G X;  5JN5 A;  1P5D X;  4QG5 A;  3C04 A;  4WXA A;  3OLP A;  5EPC A;  3ENC A;  3I3W A;  3UW2 A;  1C4G A;  4WX8 A;  4BJU A;  1C47 A;  5HSH A;  1PCM X;  2DKD A;  2Z0F A;  2EHP A;  4IL8 A;  1TUO A;  2FKF A;  3PMG A;  1K35 A;  5JMV D;  2FUV A;  1KFQ A; 
#chains in the Genus database with same CATH topology
 1UT7 A;  2O3O A;  2DKC A;  2R5X A;  4HJH A;  1WQA A;  4EAG A;  4EJY A;  3NA5 A;  3KRM A;  1MPG A;  3RPJ A;  1JDY A;  2FKM X;  1N3C A;  2NOL A;  4B0A A;  1P5G X;  1B9K A;  3SNS A;  1YQL A;  2MJ7 A;  2V9J A;  2JHJ A;  1QNE A;  3DPU A;  3HS8 A;  1UT4 A;  2QRD A;  1EBM A;  3D4V A;  2PWW A;  2NOI A;  1XSZ A;  2YA3 A;  1KY7 A;  3ASM A;  1YQK A;  4C7P A;  2NOZ A;  1NVP A;  5AN4 A;  1QN5 A;  2VJ0 A;  3I0W A;  2HL8 A;  4EJZ A;  2MZ8 A;  1T6A A;  3D7Q A;  3OSM A;  5F9C A;  1LWV A;  1KO9 A;  2D0B A;  1PCJ X;  2D0C A;  3OCI A;  3CVS A;  1LWY A;  2D0A A;  5IYC P;  4MRQ A;  1QN6 A;  2JPI A;  1K2Y X;  1LWW A;  1QNC A;  1VOL B;  1QN7 A;  1TBP A;  1WJW A;  2ZFD B;  1P5D X;  3N89 A;  1QN4 A;  2Y8L A;  3C04 A;  3EIK A;  4WXA A;  3I0X A;  1W80 A;  5EPC A;  1FN7 A;  3ENC A;  1VTO A;  4D7Q A;  1JFI C;  2Z8U A;  4TPS A;  1UL7 A;  1QTP A;  3UW2 A;  4EAK A;  4BJU A;  4ROE B;  1C47 A;  2EHB D;  2G30 A;  1KYU A;  2IV8 A;  2DKD A;  2EHP A;  1J3M A;  3IH7 A;  2QRE A;  4EAJ A;  3PMG A;  2HZM A;  1C4G A;  2NOE A;  1M5Q 1;  2HZS A;  4EAL A;  2EIU A;  1MP9 A;  3CWA A;  1D3U A;  1KY6 A;  1NGM A;  1AIS A;  1QN8 A;  1KFI A;  4WZS D;  3DPT A;  1KYD A;  2V8Q A;  4CFF A;  2F7L A;  2NWV A;  2QR1 A;  2H5A X;  3RSM A;  1VKL A;  5BMP A;  5IYB P;  3OGD A;  3BKQ X;  1RM1 A;  1N39 A;  2IV9 A;  2OOX A;  3ENO C;  3H1Z A;  2JHN A;  2LAE A;  1Q9U A;  1YTF A;  3OLP A;  2YH5 A;  4ROD B;  4EAI A;  3I3W A;  3F10 A;  4DUL A;  4PY5 A;  3OSE A;  1V5S A;  2HL9 A;  1N3A A;  1M3Q A;  5HSH A;  1TGH A;  2NOF A;  2XHI A;  1YTB A;  1VOK A;  1PCM X;  3CWS A;  2Z0F A;  2OOY A;  3CWU A;  4IL8 A;  4Q11 A;  3OH6 A;  2I5W A;  2NOB A;  1K35 A;  5JMV D;  2FUV A;  1KFQ A;  1VTL E;  3CW7 A;  5IYD P;  1PVS A;  2H4L X;  1R4X A;  1YQR A;  1QNA A;  5KL0 A;  2DKA A;  3PDK A;  1QNB A;  3OH9 A;  1PZD A;  3VN5 A;  1QTS A;  1CDW A;  1KYF A;  1LXT A;  3KTU A;  5BMN A;  2NVM A;  2NOH A;  3HS9 A;  1NH2 A;  3ULX A;  3T4N A;  5JN5 A;  3EAY A;  4I8O A;  2QRC A;  1C9B B;  4QG5 A;  1E42 A;  2V92 A;  3OST A;  1PCZ A;  3CWT A;  2Y8Q A;  1QN9 A;  1TBA B;  1DIZ A;  3CVT A;  1QN3 A;  4D7R A;  1M3H A;  4WX8 A;  2QLV A;  3F0Z A;  2JOI A;  3OC3 C;  3TDH A;  1YQM A;  2NLV A;  4ROC B;  1HU0 A;  3TE5 A;  2FKF A;  2FGT A;  2HKP A;  1TUO A;  1EUV A; 
#chains in the Genus database with same CATH homology
 2H4L X;  4HJH A;  2DKC A;  1WQA A;  5F9C A;  2EIU A;  3NA5 A;  2DKA A;  3PDK A;  1PCJ X;  5KL0 A;  1KFI A;  4MRQ A;  2F7L A;  1LXT A;  2JPI A;  1K2Y X;  2H5A X;  3RSM A;  1VKL A;  5BMP A;  5BMN A;  3BKQ X;  1JDY A;  2FKM X;  1WJW A;  3ENO C;  1P5G X;  5JN5 A;  1P5D X;  4QG5 A;  3C04 A;  4WXA A;  3OLP A;  5EPC A;  3ENC A;  3I3W A;  3UW2 A;  1C4G A;  4WX8 A;  4BJU A;  1C47 A;  5HSH A;  1PCM X;  2DKD A;  2Z0F A;  2EHP A;  4IL8 A;  1TUO A;  2FKF A;  3PMG A;  1K35 A;  5JMV D;  2FUV A;  1KFQ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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