4MRQA

Crystal structure of wild-type unphosphorylated pmm/pgm
Total Genus 168
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
168
sequence length
455
structure length
455
Chain Sequence
LPASIFRAYDIRGVVGDTLTAETAYWIGRAIGSESLARGEPCVAVGRDGRLSGPELVKQLIQGLVDCGCQVSDVGMVPTPVLYYAANVLEGKSGVMLTGSHNPPDYNGFKIVVAGETLANEQIQALRERIEKNDLASGVGSVEQVDILPRYFKQIRDDIAMAKPMKVVVDCGNGVAGVIAPQLIEALGCSVIPLYCEVDGNFPNHHPDPGKPENLKDLIAKVKAENADLGLAFDGDGDRVGVVTNTGTIIYPDRLLMLFAKDVVSRNPGADIIFDVKCTRRLIALISGYGGRPVMWKTGHSLIKKKMKETGALLAGEMSGHVFFKERWFGFDDGIYSAARLLEILSQDQRDSEHVFSAFPSDISTPEINITVTEDSKFAIIEALQRDAQWGEGNITTLDGVRVDYPKGWGLVRASNTTPVLVLRFEADTEEELERIKTVFRNQLKAVDSSLPVPF
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule tags Isomerase
molecule keywords Phosphomannomutase/phosphoglucomutase
publication title Promotion of enzyme flexibility by dephosphorylation and coupling to the catalytic mechanism of a phosphohexomutase.
pubmed doi rcsb
source organism Pseudomonas aeruginosa
total genus 168
structure length 455
sequence length 455
ec nomenclature ec 5.4.2.2: Phosphoglucomutase (alpha-D-glucose-1,6-bisphosphate-dependent).
pdb deposition date 2013-09-17

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00408 PGM_PMM_IV Phosphoglucomutase/phosphomannomutase, C-terminal domain
A PF02878 PGM_PMM_I Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I
A PF02879 PGM_PMM_II Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II
A PF02880 PGM_PMM_III Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.310.50 Alpha Beta 2-Layer Sandwich TATA-Binding Protein Alpha-D-phosphohexomutase, C-terminal domain 4mrqA04
3.40.120.10 Alpha Beta 3-Layer(aba) Sandwich Alpha-D-Glucose-1,6-Bisphosphate; Chain A, domain 3 Alpha-D-Glucose-1,6-Bisphosphate, subunit A, domain 3 4mrqA03
3.40.120.10 Alpha Beta 3-Layer(aba) Sandwich Alpha-D-Glucose-1,6-Bisphosphate; Chain A, domain 3 Alpha-D-Glucose-1,6-Bisphosphate, subunit A, domain 3 4mrqA01
3.40.120.10 Alpha Beta 3-Layer(aba) Sandwich Alpha-D-Glucose-1,6-Bisphosphate; Chain A, domain 3 Alpha-D-Glucose-1,6-Bisphosphate, subunit A, domain 3 4mrqA02
2FKMX 1K2YX 2FUVA 5KL0A 1VKLA 2DKCA 1P5DX 3PMGA 4HJHA 2DKAA 4QG5A 3RSMA 1TUOA 2FKFA 1WJWA 2EHPA 2H5AX 3I3WA 3C04A 5BMNA 4BJUA 5JN5A 3OLPA 1PCMX 5BMPA 1K35A 5JMVD 2Z0FA 5EPCA 4IL8A 2F7LA 5F9CA 3ENOC 1JDYA 2JPIA 2EIUA 1KFQA 3UW2A 2H4LX 3ENCA 4WXAA 1WQAA 4WX8A 1P5GX 1C4GA 1LXTA 3PDKA 3NA5A 5HSHA 1KFIA 1C47A 3BKQX 4MRQA 1PCJX 2DKDA
chains in the Genus database with same CATH superfamily
3HS8A 1VKLA 5AN4A 2QRCA 1QTSA 1D3UA 1UT7A 2VJ0A 3I3WA 3H1ZA 5JN5A 1QNCA 1QNAA 1V5SA 3OSMA 3ULXA 1AISA 1CDWA 2NOLA 2LAEA 4B0AA 1QN4A 2QREA 3KRMA 1M3QA 3F0ZA 2ZFDB 5IYCP 1N3AA 1C9BB 1KFQA 2IV8A 1NGMA 1B9KA 3EAYA 3UW2A 2HL8A 4WXAA 4WX8A 3IH7A 1WQAA 2NOBA 3OGDA 5IYDP 1P5GX 2V92A 2OOXA 1J3MA 2PWWA 3OC3C 1QN7A 5HSHA 2D0BA 1KFIA 3CVSA 3I0WA 1C47A 1HU0A 1DIZA 2QRDA 1QN9A 1K2YX 2FUVA 2Y8QA 1N3CA 1TGHA 3CWSA 1QTPA 2G30A 3RSMA 1TUOA 2FKFA 3OCIA 1WJWA 2H5AX 2NLVA 1LWYA 4D7QA 1KO9A 2I5WA 4BJUA 2Z8UA 1M3HA 3OSEA 1PCMX 1QN3A 1QN6A 5BMPA 2NOFA 4PY5A 1K35A 4DULA 2Z0FA 3CWUA 1UT4A 2F7LA 1KY7A 2HZSA 2O3OA 2Y8LA 1NH2A 2H4LX 2YA3A 1N39A 1VOLB 1PCZA 3D7QA 3EIKA 3KTUA 2IV9A 3CW7A 3NA5A 1PZDA 1LWVA 4TPSA 3CWTA 4MRQA 1PCJX 1W80A 3T4NA 2QR1A 2FKMX 2NWVA 3VN5A 2HKPA 1FN7A 2HL9A 4HJHA 1KYFA 3PMGA 2DKAA 1MPGA 4EAKA 4Q11A 3TDHA 1VTOA 1QNEA 4ROCB 1QN8A 2YH5A 2JHJA 3RPJA 1LWWA 2FGTA 2NVMA 1KY6A 2V8QA 4EALA 2JOIA 1KYDA 2QLVA 4ROEB 4EAJA 1RM1A 2NOEA 1XSZA 1YQMA 2D0AA 1QN5A 1VOKA 1JDYA 2JPIA 1R4XA 1MP9A 2EIUA 4WZSD 1YTBA 1YQLA 4I8OA 4RODB 3OH9A 1LXTA 3CWAA 3PDKA 4C7PA 2XHIA 3D4VA 2EHBD 3CVTA 1Q9UA 2JHNA 1M5Q1 2NOHA 3ASMA 3ENCA 1JFIC 2R5XA 1QNBA 1E42A 1EBMA 2HZMA 1EUVA 3OSTA 4CFFA 5KL0A 3HS9A 2DKCA 1P5DX 1PVSA 2V9JA 3I0XA 2EHPA 2NOIA 2NOZA 2D0CA 4EJYA 3C04A 4EJZA 3DPUA 1TBPA 5IYBP 5BMNA 1NVPA 3OLPA 1YQRA 2MJ7A 5JMVD 5EPCA 4IL8A 5F9CA 1UL7A 4D7RA 3TE5A 3ENOC 1YTFA 3SNSA 1KYUA 3N89A 2MZ8A 4EAIA 1YQKA 1C4GA 1VTLE 3DPTA 1TBAB 4EAGA 3OH6A 2OOYA 3BKQX 1T6AA 4QG5A 2DKDA 3F10A
chains in the Genus database with same CATH topology
2FKMX 1K2YX 2FUVA 5KL0A 1VKLA 2DKCA 1P5DX 3PMGA 4HJHA 2DKAA 4QG5A 3RSMA 1TUOA 2FKFA 1WJWA 2EHPA 2H5AX 3I3WA 3C04A 5BMNA 4BJUA 5JN5A 3OLPA 1PCMX 5BMPA 1K35A 5JMVD 2Z0FA 5EPCA 4IL8A 2F7LA 5F9CA 3ENOC 1JDYA 2JPIA 2EIUA 1KFQA 3UW2A 2H4LX 3ENCA 4WXAA 1WQAA 4WX8A 1P5GX 1C4GA 1LXTA 3PDKA 3NA5A 5HSHA 1KFIA 1C47A 3BKQX 4MRQA 1PCJX 2DKDA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2FKM X;  1K2Y X;  2FUV A;  5KL0 A;  1VKL A;  2DKC A;  1P5D X;  3PMG A;  4HJH A;  2DKA A;  4QG5 A;  3RSM A;  1TUO A;  2FKF A;  1WJW A;  2EHP A;  2H5A X;  3I3W A;  3C04 A;  5BMN A;  4BJU A;  5JN5 A;  3OLP A;  1PCM X;  5BMP A;  1K35 A;  5JMV D;  2Z0F A;  5EPC A;  4IL8 A;  2F7L A;  5F9C A;  3ENO C;  1JDY A;  2JPI A;  2EIU A;  1KFQ A;  3UW2 A;  2H4L X;  3ENC A;  4WXA A;  1WQA A;  4WX8 A;  1P5G X;  1C4G A;  1LXT A;  3PDK A;  3NA5 A;  5HSH A;  1KFI A;  1C47 A;  3BKQ X;  4MRQ A;  1PCJ X;  2DKD A; 
#chains in the Genus database with same CATH topology
 3HS8 A;  1VKL A;  5AN4 A;  2QRC A;  1QTS A;  1D3U A;  1UT7 A;  2VJ0 A;  3I3W A;  3H1Z A;  5JN5 A;  1QNC A;  1QNA A;  1V5S A;  3OSM A;  3ULX A;  1AIS A;  1CDW A;  2NOL A;  2LAE A;  4B0A A;  1QN4 A;  2QRE A;  3KRM A;  1M3Q A;  3F0Z A;  2ZFD B;  5IYC P;  1N3A A;  1C9B B;  1KFQ A;  2IV8 A;  1NGM A;  1B9K A;  3EAY A;  3UW2 A;  2HL8 A;  4WXA A;  4WX8 A;  3IH7 A;  1WQA A;  2NOB A;  3OGD A;  5IYD P;  1P5G X;  2V92 A;  2OOX A;  1J3M A;  2PWW A;  3OC3 C;  1QN7 A;  5HSH A;  2D0B A;  1KFI A;  3CVS A;  3I0W A;  1C47 A;  1HU0 A;  1DIZ A;  2QRD A;  1QN9 A;  1K2Y X;  2FUV A;  2Y8Q A;  1N3C A;  1TGH A;  3CWS A;  1QTP A;  2G30 A;  3RSM A;  1TUO A;  2FKF A;  3OCI A;  1WJW A;  2H5A X;  2NLV A;  1LWY A;  4D7Q A;  1KO9 A;  2I5W A;  4BJU A;  2Z8U A;  1M3H A;  3OSE A;  1PCM X;  1QN3 A;  1QN6 A;  5BMP A;  2NOF A;  4PY5 A;  1K35 A;  4DUL A;  2Z0F A;  3CWU A;  1UT4 A;  2F7L A;  1KY7 A;  2HZS A;  2O3O A;  2Y8L A;  1NH2 A;  2H4L X;  2YA3 A;  1N39 A;  1VOL B;  1PCZ A;  3D7Q A;  3EIK A;  3KTU A;  2IV9 A;  3CW7 A;  3NA5 A;  1PZD A;  1LWV A;  4TPS A;  3CWT A;  4MRQ A;  1PCJ X;  1W80 A;  3T4N A;  2QR1 A;  2FKM X;  2NWV A;  3VN5 A;  2HKP A;  1FN7 A;  2HL9 A;  4HJH A;  1KYF A;  3PMG A;  2DKA A;  1MPG A;  4EAK A;  4Q11 A;  3TDH A;  1VTO A;  1QNE A;  4ROC B;  1QN8 A;  2YH5 A;  2JHJ A;  3RPJ A;  1LWW A;  2FGT A;  2NVM A;  1KY6 A;  2V8Q A;  4EAL A;  2JOI A;  1KYD A;  2QLV A;  4ROE B;  4EAJ A;  1RM1 A;  2NOE A;  1XSZ A;  1YQM A;  2D0A A;  1QN5 A;  1VOK A;  1JDY A;  2JPI A;  1R4X A;  1MP9 A;  2EIU A;  4WZS D;  1YTB A;  1YQL A;  4I8O A;  4ROD B;  3OH9 A;  1LXT A;  3CWA A;  3PDK A;  4C7P A;  2XHI A;  3D4V A;  2EHB D;  3CVT A;  1Q9U A;  2JHN A;  1M5Q 1;  2NOH A;  3ASM A;  3ENC A;  1JFI C;  2R5X A;  1QNB A;  1E42 A;  1EBM A;  2HZM A;  1EUV A;  3OST A;  4CFF A;  5KL0 A;  3HS9 A;  2DKC A;  1P5D X;  1PVS A;  2V9J A;  3I0X A;  2EHP A;  2NOI A;  2NOZ A;  2D0C A;  4EJY A;  3C04 A;  4EJZ A;  3DPU A;  1TBP A;  5IYB P;  5BMN A;  1NVP A;  3OLP A;  1YQR A;  2MJ7 A;  5JMV D;  5EPC A;  4IL8 A;  5F9C A;  1UL7 A;  4D7R A;  3TE5 A;  3ENO C;  1YTF A;  3SNS A;  1KYU A;  3N89 A;  2MZ8 A;  4EAI A;  1YQK A;  1C4G A;  1VTL E;  3DPT A;  1TBA B;  4EAG A;  3OH6 A;  2OOY A;  3BKQ X;  1T6A A;  4QG5 A;  2DKD A;  3F10 A; 
#chains in the Genus database with same CATH homology
 2FKM X;  1K2Y X;  2FUV A;  5KL0 A;  1VKL A;  2DKC A;  1P5D X;  3PMG A;  4HJH A;  2DKA A;  4QG5 A;  3RSM A;  1TUO A;  2FKF A;  1WJW A;  2EHP A;  2H5A X;  3I3W A;  3C04 A;  5BMN A;  4BJU A;  5JN5 A;  3OLP A;  1PCM X;  5BMP A;  1K35 A;  5JMV D;  2Z0F A;  5EPC A;  4IL8 A;  2F7L A;  5F9C A;  3ENO C;  1JDY A;  2JPI A;  2EIU A;  1KFQ A;  3UW2 A;  2H4L X;  3ENC A;  4WXA A;  1WQA A;  4WX8 A;  1P5G X;  1C4G A;  1LXT A;  3PDK A;  3NA5 A;  5HSH A;  1KFI A;  1C47 A;  3BKQ X;  4MRQ A;  1PCJ X;  2DKD A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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