2Y8QA

Structure of the regulatory fragment of mammalian ampk in complex with one adp
Total Genus 23
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
23
sequence length
158
structure length
104
Chain Sequence
SMAWHLGIRSQSRPNDIMAEVCRAIKQLDYEWKVVNPYYLRVRRKNPVTSTFSKMSLQLYQVDSRTYLLDFRSIDDEVAPRPGSHTIEFFEMCANLIKNSCTVN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule keywords 5'-AMP-ACTIVATED PROTEIN KINASE CATALYTIC SUBUNIT ALPHA-1
publication title Structure of Mammalian Ampk and its Regulation by Adp
pubmed doi rcsb
source organism Rattus norvegicus
molecule tags Transferase
total genus 23
structure length 104
sequence length 158
ec nomenclature ec 2.7.11.1: Non-specific serine/threonine protein kinase.
pdb deposition date 2011-02-09
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.310.80 Alpha Beta 2-Layer Sandwich TATA-Binding Protein Kinase associated domain 1, KA1 2y8qA01
3OSEA 2QREA 2V9JA 4EAIA 4EAKA 2OOXA 2OOYA 3T4NA 2QRDA 3TE5A 2QR1A 2QRCA 4EAGA 2ZFDB 2Y8QA 2EHBD 3TDHA 4EAJA 1V5SA 4EALA 1UL7A 2YA3A 2V92A 4CFFA 2V8QA 2QLVA 2Y8LA
chains in the Genus database with same CATH superfamily
2NOBA 1K2YX 1PVSA 3F0ZA 3HS9A 2I5WA 2HZSA 2VJ0A 3PDKA 1YQRA 3SNSA 2OOXA 5IYCP 4I8OA 1M3HA 1QN9A 4PY5A 3CWSA 2F7LA 2IV9A 3H1ZA 4D7RA 2QR1A 4EAGA 3CVTA 4WZSD 2HL9A 1PCZA 1K35A 3N89A 1PCJX 1LXTA 2XHIA 5BMNA 3PMGA 1MP9A 5EPCA 2EHBD 1CDWA 2FKFA 1V5SA 1N39A 3C04A 1QTSA 1UL7A 4ROCB 2V92A 1UT4A 1KYFA 2HKPA 1KY6A 4QG5A 2QLVA 3BKQX 4BJUA 3ENCA 1QN3A 2Y8LA 3OSEA 3ASMA 2V9JA 2YH5A 2NOHA 3HS8A 1KFIA 1VKLA 5AN4A 4D7QA 5JMVD 2NOIA 1VTOA 2OOYA 2DKAA 1JDYA 1EBMA 1C4GA 3TE5A 4C7PA 3OGDA 5F9CA 2QRCA 1XSZA 3CW7A 2H5AX 1QNEA 1MPGA 2ZFDB 1JFIC 3F10A 3I0WA 1QN4A 1KYDA 3TDHA 1KY7A 1Q9UA 4EALA 2FGTA 1WQAA 2FUVA 2HL8A 3OSTA 1FN7A 4CFFA 3NA5A 3RSMA 5KL0A 1C47A 3ULXA 3VN5A 1VOKA 5JN5A 1QN5A 1QNCA 1VOLB 4EJYA 4MRQA 1T6AA 1YQLA 1B9KA 2HZMA 3OSMA 4B0AA 1YTBA 1PZDA 2O3OA 1TBAB 3EIKA 4EAIA 3KTUA 4EAKA 1QNBA 2H4LX 2QRDA 3T4NA 5IYBP 2JOIA 3I0XA 5HSHA 2NLVA 2PWWA 4RODB 1TUOA 2NWVA 3DPTA 1M3QA 3ENOC 2DKCA 2FKMX 2MZ8A 1WJWA 3RPJA 2R5XA 1E42A 2G30A 4ROEB 1QN6A 3DPUA 3OLPA 1QNAA 1N3CA 3CWTA 4Q11A 3OC3C 2D0CA 1KYUA 2NOFA 1DIZA 1TBPA 2DKDA 1NGMA 1N3AA 2IV8A 1R4XA 4TPSA 1J3MA 3CWAA 1YQMA 3CWUA 2NOZA 2D0AA 1M5Q1 2JHNA 2QREA 3EAYA 3UW2A 2NOEA 3I3WA 2MJ7A 4WXAA 3D4VA 1D3UA 2JPIA 1UT7A 1YTFA 2NVMA 1QN7A 4HJHA 4WX8A 1PCMX 1AISA 3KRMA 1KO9A 1RM1A 1NH2A 5BMPA 1NVPA 1LWVA 2D0BA 3IH7A 5IYDP 1TGHA 1W80A 3OCIA 1LWYA 1P5DX 2Y8QA 2JHJA 3OH6A 1HU0A 2LAEA 4EAJA 1LWWA 2YA3A 1C9BB 1P5GX 1EUVA 2V8QA 3CVSA 3D7QA 4DULA 1QN8A 4EJZA 2NOLA 4IL8A 1VTLE 1KFQA 1YQKA 3OH9A 1QTPA 2Z8UA 2Z0FA
chains in the Genus database with same CATH topology
3OSEA 2QREA 2V9JA 4EAIA 4EAKA 2OOXA 2OOYA 3T4NA 2QRDA 3TE5A 2QR1A 2QRCA 4EAGA 2ZFDB 2Y8QA 2EHBD 3TDHA 4EAJA 1V5SA 4EALA 1UL7A 2YA3A 2V92A 4CFFA 2V8QA 2QLVA 2Y8LA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3OSE A;  2QRE A;  2V9J A;  4EAI A;  4EAK A;  2OOX A;  2OOY A;  3T4N A;  2QRD A;  3TE5 A;  2QR1 A;  2QRC A;  4EAG A;  2ZFD B;  2Y8Q A;  2EHB D;  3TDH A;  4EAJ A;  1V5S A;  4EAL A;  1UL7 A;  2YA3 A;  2V92 A;  4CFF A;  2V8Q A;  2QLV A;  2Y8L A; 
#chains in the Genus database with same CATH topology
 2NOB A;  1K2Y X;  1PVS A;  3F0Z A;  3HS9 A;  2I5W A;  2HZS A;  2VJ0 A;  3PDK A;  1YQR A;  3SNS A;  2OOX A;  5IYC P;  4I8O A;  1M3H A;  1QN9 A;  4PY5 A;  3CWS A;  2F7L A;  2IV9 A;  3H1Z A;  4D7R A;  2QR1 A;  4EAG A;  3CVT A;  4WZS D;  2HL9 A;  1PCZ A;  1K35 A;  3N89 A;  1PCJ X;  1LXT A;  2XHI A;  5BMN A;  3PMG A;  1MP9 A;  5EPC A;  2EHB D;  1CDW A;  2FKF A;  1V5S A;  1N39 A;  3C04 A;  1QTS A;  1UL7 A;  4ROC B;  2V92 A;  1UT4 A;  1KYF A;  2HKP A;  1KY6 A;  4QG5 A;  2QLV A;  3BKQ X;  4BJU A;  3ENC A;  1QN3 A;  2Y8L A;  3OSE A;  3ASM A;  2V9J A;  2YH5 A;  2NOH A;  3HS8 A;  1KFI A;  1VKL A;  5AN4 A;  4D7Q A;  5JMV D;  2NOI A;  1VTO A;  2OOY A;  2DKA A;  1JDY A;  1EBM A;  1C4G A;  3TE5 A;  4C7P A;  3OGD A;  5F9C A;  2QRC A;  1XSZ A;  3CW7 A;  2H5A X;  1QNE A;  1MPG A;  2ZFD B;  1JFI C;  3F10 A;  3I0W A;  1QN4 A;  1KYD A;  3TDH A;  1KY7 A;  1Q9U A;  4EAL A;  2FGT A;  1WQA A;  2FUV A;  2HL8 A;  3OST A;  1FN7 A;  4CFF A;  3NA5 A;  3RSM A;  5KL0 A;  1C47 A;  3ULX A;  3VN5 A;  1VOK A;  5JN5 A;  1QN5 A;  1QNC A;  1VOL B;  4EJY A;  4MRQ A;  1T6A A;  1YQL A;  1B9K A;  2HZM A;  3OSM A;  4B0A A;  1YTB A;  1PZD A;  2O3O A;  1TBA B;  3EIK A;  4EAI A;  3KTU A;  4EAK A;  1QNB A;  2H4L X;  2QRD A;  3T4N A;  5IYB P;  2JOI A;  3I0X A;  5HSH A;  2NLV A;  2PWW A;  4ROD B;  1TUO A;  2NWV A;  3DPT A;  1M3Q A;  3ENO C;  2DKC A;  2FKM X;  2MZ8 A;  1WJW A;  3RPJ A;  2R5X A;  1E42 A;  2G30 A;  4ROE B;  1QN6 A;  3DPU A;  3OLP A;  1QNA A;  1N3C A;  3CWT A;  4Q11 A;  3OC3 C;  2D0C A;  1KYU A;  2NOF A;  1DIZ A;  1TBP A;  2DKD A;  1NGM A;  1N3A A;  2IV8 A;  1R4X A;  4TPS A;  1J3M A;  3CWA A;  1YQM A;  3CWU A;  2NOZ A;  2D0A A;  1M5Q 1;  2JHN A;  2QRE A;  3EAY A;  3UW2 A;  2NOE A;  3I3W A;  2MJ7 A;  4WXA A;  3D4V A;  1D3U A;  2JPI A;  1UT7 A;  1YTF A;  2NVM A;  1QN7 A;  4HJH A;  4WX8 A;  1PCM X;  1AIS A;  3KRM A;  1KO9 A;  1RM1 A;  1NH2 A;  5BMP A;  1NVP A;  1LWV A;  2D0B A;  3IH7 A;  5IYD P;  1TGH A;  1W80 A;  3OCI A;  1LWY A;  1P5D X;  2Y8Q A;  2JHJ A;  3OH6 A;  1HU0 A;  2LAE A;  4EAJ A;  1LWW A;  2YA3 A;  1C9B B;  1P5G X;  1EUV A;  2V8Q A;  3CVS A;  3D7Q A;  4DUL A;  1QN8 A;  4EJZ A;  2NOL A;  4IL8 A;  1VTL E;  1KFQ A;  1YQK A;  3OH9 A;  1QTP A;  2Z8U A;  2Z0F A; 
#chains in the Genus database with same CATH homology
 3OSE A;  2QRE A;  2V9J A;  4EAI A;  4EAK A;  2OOX A;  2OOY A;  3T4N A;  2QRD A;  3TE5 A;  2QR1 A;  2QRC A;  4EAG A;  2ZFD B;  2Y8Q A;  2EHB D;  3TDH A;  4EAJ A;  1V5S A;  4EAL A;  1UL7 A;  2YA3 A;  2V92 A;  4CFF A;  2V8Q A;  2QLV A;  2Y8L A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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