5IYBP

Human core-pic in the open state
Total Genus 43
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
43
sequence length
185
structure length
185
Chain Sequence
TPASESSGIVPQLQNIVSTVNLGCKLDLKTIALRARNAEYNPKRFAAVIMRIREPRTTALIFSSGKMVCTGAKSEEQSRLAARKYARVVQKLGFPAKFLDFKIQNMVGSCDVKFPIRLEGLVLTHQQFSSYEPELFPGLIYRMIKPRIVLLIFVSGKVVLTGAKVRAEIYEAFENIYPILKGFRK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Near-atomic resolution visualization of human transcription promoter opening.
pubmed doi rcsb
molecule tags Transcription, transferase/dna
source organism Homo sapiens
molecule keywords DNA-directed RNA polymerase II subunit RPB1
total genus 43
structure length 185
sequence length 185
ec nomenclature
pdb deposition date 2016-03-24

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
P PF00352 TBP Transcription factor TFIID (or TATA-binding protein, TBP)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.310.10 Alpha Beta 2-Layer Sandwich TATA-Binding Protein TATA-Binding Protein 5iybP01
3.30.310.10 Alpha Beta 2-Layer Sandwich TATA-Binding Protein TATA-Binding Protein 5iybP02
1W80A 1QTSA 2VJ0A 1QN5A 2D0CA 5IYCP 1KY6A 2D0BA 2G30A 1AISA 1QN4A 1QN6A 1TBAB 1YTFA 1NH2A 1KYDA 3HS8A 1C9BB 1VOKA 1QTPA 1VTLE 1VOLB 4ROEB 2MJ7A 1QN9A 4WZSD 1TGHA 1PCZA 2IV9A 1NVPA 1QNAA 4ROCB 3H1ZA 1KY7A 1NGMA 1YTBA 1E42A 3OCIA 1RM1A 1R4XA 3ASMA 2IV8A 1QNEA 3VN5A 4RODB 1B9KA 1MP9A 3HS9A 1QNCA 1QN7A 3OC3C 1PZDA 1QN8A 1QN3A 1TBPA 3EIKA 4B0AA 1QNBA 1KYFA 2Z8UA 1D3UA 5IYDP 4PY5A 1KYUA 1VTOA 2D0AA 1CDWA 1JFIC 5IYBP
chains in the Genus database with same CATH superfamily
1XSZA 2NOEA 4EAKA 1QTSA 2VJ0A 3OSMA 1YQLA 1QN6A 2G30A 5EPCA 1QN4A 4MRQA 1TBAB 2NOFA 3CWUA 3HS8A 1T6AA 2FKFA 1VOKA 1VTLE 2O3OA 4WX8A 1M3QA 2HZSA 1DIZA 1TGHA 2IV9A 5HSHA 5JMVD 2Y8LA 3OGDA 1KY7A 4EAGA 3CVSA 1JFIC 3ASMA 1Q9UA 1QNEA 2OOXA 1TUOA 2OOYA 3D7QA 3TDHA 1QN7A 3OC3C 2NOZA 1JDYA 1PZDA 1QN8A 1J3MA 3CWTA 1LWVA 1K2YX 4B0AA 4EAIA 4PY5A 2QRDA 2FUVA 1KYUA 2NOLA 4CFFA 5JN5A 1C4GA 2F7LA 1EUVA 2Z0FA 5BMPA 5IYBP 1M5Q1 3EAYA 3OLPA 1LWYA 2R5XA 3F0ZA 1HU0A 3OH9A 1AISA 5IYCP 2MZ8A 1KFIA 3ULXA 1FN7A 4D7QA 1P5GX 1KYDA 3I0WA 1NH2A 1QTPA 3I0XA 3OSTA 3N89A 1QN9A 2H5AX 1PCZA 5F9CA 1NVPA 2QLVA 5KL0A 3C04A 3RSMA 2LAEA 4ROCB 2NOIA 2DKAA 2HZMA 3OCIA 3DPUA 4EALA 5BMNA 3HS9A 1VKLA 2HL9A 2QREA 1C47A 2NWVA 3CW7A 2YH5A 3TE5A 2NOHA 4D7RA 3NA5A 2HKPA 2DKCA 3BKQX 2JOIA 2QRCA 1PCMX 3OSEA 1EBMA 1QNBA 4C7PA 2XHIA 2D0AA 1CDWA 3CWSA 1LXTA 2PWWA 3SNSA 3CWAA 2FGTA 2YA3A 2NOBA 1N3AA 2H4LX 1C9BB 3RPJA 1YQRA 1PCJX 2FKMX 4ROEB 4WZSD 1QNAA 2ZFDB 2JPIA 3H1ZA 1YTBA 1E42A 1RM1A 4EJZA 1R4XA 2NVMA 1UL7A 3ENCA 4I8OA 1MP9A 1WQAA 3VN5A 4RODB 1M3HA 4QG5A 1N39A 2Y8QA 4Q11A 3KTUA 1UT4A 4DULA 2DKDA 2NLVA 1TBPA 3EIKA 2HL8A 2V9JA 2I5WA 1D3UA 5IYDP 3OH6A 3UW2A 3DPTA 3PDKA 5AN4A 3IH7A 1W80A 2JHNA 4HJHA 1PVSA 1QN5A 2D0CA 1YTFA 1KY6A 2D0BA 1P5DX 3D4VA 1YQKA 1VOLB 3ENOC 1LWWA 3KRMA 2MJ7A 3T4NA 2EHBD 4TPSA 4BJUA 1YQMA 1K35A 4WXAA 4EAJA 3CVTA 1NGMA 1MPGA 2IV8A 1UT7A 1B9KA 1QNCA 1N3CA 2V92A 2V8QA 3PMGA 2QR1A 3F10A 1WJWA 1QN3A 1KFQA 4IL8A 4EJYA 1KYFA 2Z8UA 1V5SA 2JHJA 1VTOA 3I3WA 1KO9A
chains in the Genus database with same CATH topology
2NOEA 1QTSA 2VJ0A 3OSMA 1YQLA 1QN6A 2G30A 1QN4A 1TBAB 2NOFA 3HS8A 1VOKA 1VTLE 2O3OA 1M3QA 2HZSA 1TGHA 2IV9A 1KY7A 3ASMA 1QNEA 1QN7A 3OC3C 2NOZA 1PZDA 1QN8A 1LWVA 4B0AA 4PY5A 1KYUA 2NOLA 5IYBP 1LWYA 3F0ZA 1HU0A 1AISA 5IYCP 2MZ8A 3ULXA 1FN7A 1NH2A 1KYDA 3I0WA 1QTPA 3I0XA 3OSTA 3N89A 1QN9A 1PCZA 1NVPA 2LAEA 4ROCB 2NOIA 2HZMA 3OCIA 3DPUA 3HS9A 2YH5A 2NOHA 1QNBA 1EBMA 2JOIA 2XHIA 2D0AA 1CDWA 3SNSA 2FGTA 2NOBA 1N3AA 1C9BB 3RPJA 1YQRA 4ROEB 4WZSD 1QNAA 3H1ZA 1YTBA 1E42A 1RM1A 4EJZA 1R4XA 4I8OA 3VN5A 4RODB 1MP9A 1M3HA 1N39A 4Q11A 3KTUA 1UT4A 4DULA 1TBPA 3EIKA 2I5WA 1D3UA 5IYDP 3DPTA 3IH7A 5AN4A 1W80A 1QN5A 2D0CA 1YTFA 1KY6A 2D0BA 1YQKA 1VOLB 1LWWA 3KRMA 2MJ7A 1YQMA 4TPSA 1NGMA 2IV8A 1UT7A 1B9KA 1QNCA 1N3CA 3F10A 1QN3A 4EJYA 1KYFA 2Z8UA 1VTOA 1JFIC 1KO9A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1W80 A;  1QTS A;  2VJ0 A;  1QN5 A;  2D0C A;  5IYC P;  1KY6 A;  2D0B A;  2G30 A;  1AIS A;  1QN4 A;  1QN6 A;  1TBA B;  1YTF A;  1NH2 A;  1KYD A;  3HS8 A;  1C9B B;  1VOK A;  1QTP A;  1VTL E;  1VOL B;  4ROE B;  2MJ7 A;  1QN9 A;  4WZS D;  1TGH A;  1PCZ A;  2IV9 A;  1NVP A;  1QNA A;  4ROC B;  3H1Z A;  1KY7 A;  1NGM A;  1YTB A;  1E42 A;  3OCI A;  1RM1 A;  1R4X A;  3ASM A;  2IV8 A;  1QNE A;  3VN5 A;  4ROD B;  1B9K A;  1MP9 A;  3HS9 A;  1QNC A;  1QN7 A;  3OC3 C;  1PZD A;  1QN8 A;  1QN3 A;  1TBP A;  3EIK A;  4B0A A;  1QNB A;  1KYF A;  2Z8U A;  1D3U A;  5IYD P;  4PY5 A;  1KYU A;  1VTO A;  2D0A A;  1CDW A;  1JFI C;  5IYB P; 
#chains in the Genus database with same CATH topology
 1XSZ A;  2NOE A;  4EAK A;  1QTS A;  2VJ0 A;  3OSM A;  1YQL A;  1QN6 A;  2G30 A;  5EPC A;  1QN4 A;  4MRQ A;  1TBA B;  2NOF A;  3CWU A;  3HS8 A;  1T6A A;  2FKF A;  1VOK A;  1VTL E;  2O3O A;  4WX8 A;  1M3Q A;  2HZS A;  1DIZ A;  1TGH A;  2IV9 A;  5HSH A;  5JMV D;  2Y8L A;  3OGD A;  1KY7 A;  4EAG A;  3CVS A;  1JFI C;  3ASM A;  1Q9U A;  1QNE A;  2OOX A;  1TUO A;  2OOY A;  3D7Q A;  3TDH A;  1QN7 A;  3OC3 C;  2NOZ A;  1JDY A;  1PZD A;  1QN8 A;  1J3M A;  3CWT A;  1LWV A;  1K2Y X;  4B0A A;  4EAI A;  4PY5 A;  2QRD A;  2FUV A;  1KYU A;  2NOL A;  4CFF A;  5JN5 A;  1C4G A;  2F7L A;  1EUV A;  2Z0F A;  5BMP A;  5IYB P;  1M5Q 1;  3EAY A;  3OLP A;  1LWY A;  2R5X A;  3F0Z A;  1HU0 A;  3OH9 A;  1AIS A;  5IYC P;  2MZ8 A;  1KFI A;  3ULX A;  1FN7 A;  4D7Q A;  1P5G X;  1KYD A;  3I0W A;  1NH2 A;  1QTP A;  3I0X A;  3OST A;  3N89 A;  1QN9 A;  2H5A X;  1PCZ A;  5F9C A;  1NVP A;  2QLV A;  5KL0 A;  3C04 A;  3RSM A;  2LAE A;  4ROC B;  2NOI A;  2DKA A;  2HZM A;  3OCI A;  3DPU A;  4EAL A;  5BMN A;  3HS9 A;  1VKL A;  2HL9 A;  2QRE A;  1C47 A;  2NWV A;  3CW7 A;  2YH5 A;  3TE5 A;  2NOH A;  4D7R A;  3NA5 A;  2HKP A;  2DKC A;  3BKQ X;  2JOI A;  2QRC A;  1PCM X;  3OSE A;  1EBM A;  1QNB A;  4C7P A;  2XHI A;  2D0A A;  1CDW A;  3CWS A;  1LXT A;  2PWW A;  3SNS A;  3CWA A;  2FGT A;  2YA3 A;  2NOB A;  1N3A A;  2H4L X;  1C9B B;  3RPJ A;  1YQR A;  1PCJ X;  2FKM X;  4ROE B;  4WZS D;  1QNA A;  2ZFD B;  2JPI A;  3H1Z A;  1YTB A;  1E42 A;  1RM1 A;  4EJZ A;  1R4X A;  2NVM A;  1UL7 A;  3ENC A;  4I8O A;  1MP9 A;  1WQA A;  3VN5 A;  4ROD B;  1M3H A;  4QG5 A;  1N39 A;  2Y8Q A;  4Q11 A;  3KTU A;  1UT4 A;  4DUL A;  2DKD A;  2NLV A;  1TBP A;  3EIK A;  2HL8 A;  2V9J A;  2I5W A;  1D3U A;  5IYD P;  3OH6 A;  3UW2 A;  3DPT A;  3PDK A;  5AN4 A;  3IH7 A;  1W80 A;  2JHN A;  4HJH A;  1PVS A;  1QN5 A;  2D0C A;  1YTF A;  1KY6 A;  2D0B A;  1P5D X;  3D4V A;  1YQK A;  1VOL B;  3ENO C;  1LWW A;  3KRM A;  2MJ7 A;  3T4N A;  2EHB D;  4TPS A;  4BJU A;  1YQM A;  1K35 A;  4WXA A;  4EAJ A;  3CVT A;  1NGM A;  1MPG A;  2IV8 A;  1UT7 A;  1B9K A;  1QNC A;  1N3C A;  2V92 A;  2V8Q A;  3PMG A;  2QR1 A;  3F10 A;  1WJW A;  1QN3 A;  1KFQ A;  4IL8 A;  4EJY A;  1KYF A;  2Z8U A;  1V5S A;  2JHJ A;  1VTO A;  3I3W A;  1KO9 A; 
#chains in the Genus database with same CATH homology
 2NOE A;  1QTS A;  2VJ0 A;  3OSM A;  1YQL A;  1QN6 A;  2G30 A;  1QN4 A;  1TBA B;  2NOF A;  3HS8 A;  1VOK A;  1VTL E;  2O3O A;  1M3Q A;  2HZS A;  1TGH A;  2IV9 A;  1KY7 A;  3ASM A;  1QNE A;  1QN7 A;  3OC3 C;  2NOZ A;  1PZD A;  1QN8 A;  1LWV A;  4B0A A;  4PY5 A;  1KYU A;  2NOL A;  5IYB P;  1LWY A;  3F0Z A;  1HU0 A;  1AIS A;  5IYC P;  2MZ8 A;  3ULX A;  1FN7 A;  1NH2 A;  1KYD A;  3I0W A;  1QTP A;  3I0X A;  3OST A;  3N89 A;  1QN9 A;  1PCZ A;  1NVP A;  2LAE A;  4ROC B;  2NOI A;  2HZM A;  3OCI A;  3DPU A;  3HS9 A;  2YH5 A;  2NOH A;  1QNB A;  1EBM A;  2JOI A;  2XHI A;  2D0A A;  1CDW A;  3SNS A;  2FGT A;  2NOB A;  1N3A A;  1C9B B;  3RPJ A;  1YQR A;  4ROE B;  4WZS D;  1QNA A;  3H1Z A;  1YTB A;  1E42 A;  1RM1 A;  4EJZ A;  1R4X A;  4I8O A;  3VN5 A;  4ROD B;  1MP9 A;  1M3H A;  1N39 A;  4Q11 A;  3KTU A;  1UT4 A;  4DUL A;  1TBP A;  3EIK A;  2I5W A;  1D3U A;  5IYD P;  3DPT A;  3IH7 A;  5AN4 A;  1W80 A;  1QN5 A;  2D0C A;  1YTF A;  1KY6 A;  2D0B A;  1YQK A;  1VOL B;  1LWW A;  3KRM A;  2MJ7 A;  1YQM A;  4TPS A;  1NGM A;  2IV8 A;  1UT7 A;  1B9K A;  1QNC A;  1N3C A;  3F10 A;  1QN3 A;  4EJY A;  1KYF A;  2Z8U A;  1VTO A;  1JFI C;  1KO9 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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