5IYCP

Human core-pic in the initial transcribing state
Total Genus 44
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
44
sequence length
185
structure length
185
Chain Sequence
TPASESSGIVPQLQNIVSTVNLGCKLDLKTIALRARNAEYNPKRFAAVIMRIREPRTTALIFSSGKMVCTGAKSEEQSRLAARKYARVVQKLGFPAKFLDFKIQNMVGSCDVKFPIRLEGLVLTHQQFSSYEPELFPGLIYRMIKPRIVLLIFVSGKVVLTGAKVRAEIYEAFENIYPILKGFRK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Near-atomic resolution visualization of human transcription promoter opening.
pubmed doi rcsb
molecule tags Transcription, transferase/dna
source organism Homo sapiens
molecule keywords DNA-directed RNA polymerase II subunit RPB1
total genus 44
structure length 185
sequence length 185
ec nomenclature
pdb deposition date 2016-03-24

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
P PF00352 TBP Transcription factor TFIID (or TATA-binding protein, TBP)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.310.10 Alpha Beta 2-Layer Sandwich TATA-Binding Protein TATA-Binding Protein 5iycP01
3.30.310.10 Alpha Beta 2-Layer Sandwich TATA-Binding Protein TATA-Binding Protein 5iycP02
2Z8UA 1AISA 1B9KA 1VOLB 1E42A 1QN3A 3ASMA 1PCZA 4WZSD 1RM1A 4ROCB 1MP9A 1W80A 4B0AA 1NH2A 1R4XA 1KY6A 1D3UA 1QN5A 1NGMA 1KYDA 1VTOA 3HS9A 1VTLE 1QN6A 1C9BB 2VJ0A 1CDWA 1TBPA 1QN7A 1PZDA 5IYDP 1TBAB 2IV9A 1KYFA 1JFIC 3OCIA 3OC3C 1QNBA 1YTBA 3HS8A 4PY5A 4ROEB 3EIKA 2D0BA 1TGHA 1QN8A 1QNEA 1KY7A 2IV8A 1KYUA 1NVPA 1QNAA 5IYBP 3H1ZA 1QNCA 2G30A 5IYCP 2D0CA 1YTFA 2D0AA 1VOKA 1QTSA 1QN9A 1QN4A 1QTPA 3VN5A 4RODB 2MJ7A
chains in the Genus database with same CATH superfamily
3I0WA 1YQLA 2NOZA 3I0XA 3ENCA 1VOLB 3CWTA 4D7QA 1RM1A 3N89A 3KRMA 4C7PA 1DIZA 3OGDA 2FKMX 2NOEA 1YQRA 1N3AA 2F7LA 1M3QA 3ENOC 3PMGA 1TUOA 2VJ0A 2NOBA 3RPJA 5KL0A 1QN7A 2QR1A 3NA5A 4Q11A 2O3OA 1VKLA 3OCIA 3OC3C 3HS8A 2Y8LA 2YA3A 5BMPA 2HKPA 1KFIA 1T6AA 2HZMA 1C47A 2NOIA 1PCJX 1N39A 1EBMA 2FKFA 1QNAA 2XHIA 2FGTA 1UT4A 3H1ZA 5F9CA 1QNCA 2G30A 2ZFDB 3I3WA 2D0AA 1VOKA 2PWWA 1QN9A 1KO9A 3CWAA 2NOLA 4EALA 1NVPA 4WXAA 2I5WA 1C4GA 1B9KA 4MRQA 2V9JA 4EAIA 2Z0FA 4D7RA 3ASMA 1PCZA 4EJYA 1W80A 4B0AA 1KY6A 1QN5A 2JPIA 1KYDA 3HS9A 2V8QA 1C9BB 2JHNA 1CDWA 3OLPA 3PDKA 1HU0A 5HSHA 4TPSA 2DKAA 1YTBA 5EPCA 2HZSA 1EUVA 4BJUA 3CVTA 3F0ZA 1J3MA 3D7QA 5JN5A 3C04A 3TDHA 1KYUA 1PCMX 3F10A 3TE5A 4EAJA 1YTFA 2NOHA 4I8OA 1QTSA 3DPUA 1YQMA 2FUVA 1QTPA 2QREA 1QN4A 2MZ8A 1AISA 2QRDA 2OOYA 5JMVD 2H4LX 1LWVA 3T4NA 3DPTA 1QN3A 4HJHA 4CFFA 4WX8A 4WZSD 4EJZA 5AN4A 4ROCB 1MP9A 1LWWA 1R4XA 2NWVA 2Y8QA 1NGMA 2EHBD 3IH7A 1K35A 1VTOA 1PVSA 1VTLE 1QN6A 1TBPA 1UT7A 1V5SA 1PZDA 2IV9A 1JFIC 3UW2A 1QNBA 4EAKA 3D4VA 2QLVA 1YQKA 2HL9A 1UL7A 1KY7A 2DKDA 5BMNA 3OH6A 5IYBP 2JHJA 1JDYA 2NLVA 1QNEA 2MJ7A 2DKCA 2Z8UA 4DULA 2LAEA 1WQAA 2NOFA 2JOIA 3OSMA 1E42A 3CWSA 1MPGA 1LXTA 1KFQA 1D3UA 1NH2A 2H5AX 2YH5A 3VN5A 2NVMA 4EAGA 2HL8A 3OH9A 3ULXA 3CWUA 1XSZA 1LWYA 3OSEA 3KTUA 2R5XA 3SNSA 1TBAB 4IL8A 1M5Q1 1KYFA 1FN7A 4PY5A 1N3CA 5IYDP 4ROEB 3EIKA 1Q9UA 2D0BA 4RODB 1TGHA 3BKQX 1QN8A 1K2YX 2V92A 2IV8A 2OOXA 1P5DX 3EAYA 5IYCP 3RSMA 2D0CA 3CVSA 3CW7A 1M3HA 1P5GX 4QG5A 1WJWA 3OSTA 2QRCA
chains in the Genus database with same CATH topology
3I0WA 1YQLA 2NOZA 3I0XA 1VOLB 1RM1A 3N89A 3KRMA 2NOEA 1YQRA 1N3AA 1M3QA 2VJ0A 2NOBA 3RPJA 1QN7A 4Q11A 2O3OA 3OCIA 3OC3C 3HS8A 2HZMA 2NOIA 1EBMA 1N39A 1QNAA 2XHIA 2FGTA 1UT4A 3H1ZA 1QNCA 2G30A 2D0AA 1VOKA 1QN9A 1KO9A 2NOLA 1NVPA 2I5WA 1B9KA 3ASMA 1PCZA 4EJYA 1W80A 4B0AA 1KY6A 1QN5A 1KYDA 3HS9A 1C9BB 1CDWA 1HU0A 4TPSA 1YTBA 2HZSA 3F0ZA 1KYUA 3F10A 1YTFA 2NOHA 4I8OA 1QTSA 3DPUA 1YQMA 1QN4A 1QTPA 2MZ8A 1AISA 1LWVA 3DPTA 1QN3A 4EJZA 4WZSD 5AN4A 4ROCB 1MP9A 1LWWA 1R4XA 1NGMA 3IH7A 1VTOA 1VTLE 1QN6A 3OSTA 1TBPA 1UT7A 1PZDA 2IV9A 1JFIC 1QNBA 1YQKA 1KY7A 5IYBP 1QNEA 2MJ7A 2Z8UA 4DULA 2LAEA 2NOFA 2JOIA 3OSMA 1E42A 1D3UA 1NH2A 2YH5A 3ULXA 1LWYA 3KTUA 1FN7A 3SNSA 1TBAB 5IYDP 1KYFA 4PY5A 1N3CA 4ROEB 3EIKA 2D0BA 1TGHA 1QN8A 2IV8A 5IYCP 2D0CA 1M3HA 3VN5A 4RODB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2Z8U A;  1AIS A;  1B9K A;  1VOL B;  1E42 A;  1QN3 A;  3ASM A;  1PCZ A;  4WZS D;  1RM1 A;  4ROC B;  1MP9 A;  1W80 A;  4B0A A;  1NH2 A;  1R4X A;  1KY6 A;  1D3U A;  1QN5 A;  1NGM A;  1KYD A;  1VTO A;  3HS9 A;  1VTL E;  1QN6 A;  1C9B B;  2VJ0 A;  1CDW A;  1TBP A;  1QN7 A;  1PZD A;  5IYD P;  1TBA B;  2IV9 A;  1KYF A;  1JFI C;  3OCI A;  3OC3 C;  1QNB A;  1YTB A;  3HS8 A;  4PY5 A;  4ROE B;  3EIK A;  2D0B A;  1TGH A;  1QN8 A;  1QNE A;  1KY7 A;  2IV8 A;  1KYU A;  1NVP A;  1QNA A;  5IYB P;  3H1Z A;  1QNC A;  2G30 A;  5IYC P;  2D0C A;  1YTF A;  2D0A A;  1VOK A;  1QTS A;  1QN9 A;  1QN4 A;  1QTP A;  3VN5 A;  4ROD B;  2MJ7 A; 
#chains in the Genus database with same CATH topology
 3I0W A;  1YQL A;  2NOZ A;  3I0X A;  3ENC A;  1VOL B;  3CWT A;  4D7Q A;  1RM1 A;  3N89 A;  3KRM A;  4C7P A;  1DIZ A;  3OGD A;  2FKM X;  2NOE A;  1YQR A;  1N3A A;  2F7L A;  1M3Q A;  3ENO C;  3PMG A;  1TUO A;  2VJ0 A;  2NOB A;  3RPJ A;  5KL0 A;  1QN7 A;  2QR1 A;  3NA5 A;  4Q11 A;  2O3O A;  1VKL A;  3OCI A;  3OC3 C;  3HS8 A;  2Y8L A;  2YA3 A;  5BMP A;  2HKP A;  1KFI A;  1T6A A;  2HZM A;  1C47 A;  2NOI A;  1PCJ X;  1N39 A;  1EBM A;  2FKF A;  1QNA A;  2XHI A;  2FGT A;  1UT4 A;  3H1Z A;  5F9C A;  1QNC A;  2G30 A;  2ZFD B;  3I3W A;  2D0A A;  1VOK A;  2PWW A;  1QN9 A;  1KO9 A;  3CWA A;  2NOL A;  4EAL A;  1NVP A;  4WXA A;  2I5W A;  1C4G A;  1B9K A;  4MRQ A;  2V9J A;  4EAI A;  2Z0F A;  4D7R A;  3ASM A;  1PCZ A;  4EJY A;  1W80 A;  4B0A A;  1KY6 A;  1QN5 A;  2JPI A;  1KYD A;  3HS9 A;  2V8Q A;  1C9B B;  2JHN A;  1CDW A;  3OLP A;  3PDK A;  1HU0 A;  5HSH A;  4TPS A;  2DKA A;  1YTB A;  5EPC A;  2HZS A;  1EUV A;  4BJU A;  3CVT A;  3F0Z A;  1J3M A;  3D7Q A;  5JN5 A;  3C04 A;  3TDH A;  1KYU A;  1PCM X;  3F10 A;  3TE5 A;  4EAJ A;  1YTF A;  2NOH A;  4I8O A;  1QTS A;  3DPU A;  1YQM A;  2FUV A;  1QTP A;  2QRE A;  1QN4 A;  2MZ8 A;  1AIS A;  2QRD A;  2OOY A;  5JMV D;  2H4L X;  1LWV A;  3T4N A;  3DPT A;  1QN3 A;  4HJH A;  4CFF A;  4WX8 A;  4WZS D;  4EJZ A;  5AN4 A;  4ROC B;  1MP9 A;  1LWW A;  1R4X A;  2NWV A;  2Y8Q A;  1NGM A;  2EHB D;  3IH7 A;  1K35 A;  1VTO A;  1PVS A;  1VTL E;  1QN6 A;  1TBP A;  1UT7 A;  1V5S A;  1PZD A;  2IV9 A;  1JFI C;  3UW2 A;  1QNB A;  4EAK A;  3D4V A;  2QLV A;  1YQK A;  2HL9 A;  1UL7 A;  1KY7 A;  2DKD A;  5BMN A;  3OH6 A;  5IYB P;  2JHJ A;  1JDY A;  2NLV A;  1QNE A;  2MJ7 A;  2DKC A;  2Z8U A;  4DUL A;  2LAE A;  1WQA A;  2NOF A;  2JOI A;  3OSM A;  1E42 A;  3CWS A;  1MPG A;  1LXT A;  1KFQ A;  1D3U A;  1NH2 A;  2H5A X;  2YH5 A;  3VN5 A;  2NVM A;  4EAG A;  2HL8 A;  3OH9 A;  3ULX A;  3CWU A;  1XSZ A;  1LWY A;  3OSE A;  3KTU A;  2R5X A;  3SNS A;  1TBA B;  4IL8 A;  1M5Q 1;  1KYF A;  1FN7 A;  4PY5 A;  1N3C A;  5IYD P;  4ROE B;  3EIK A;  1Q9U A;  2D0B A;  4ROD B;  1TGH A;  3BKQ X;  1QN8 A;  1K2Y X;  2V92 A;  2IV8 A;  2OOX A;  1P5D X;  3EAY A;  5IYC P;  3RSM A;  2D0C A;  3CVS A;  3CW7 A;  1M3H A;  1P5G X;  4QG5 A;  1WJW A;  3OST A;  2QRC A; 
#chains in the Genus database with same CATH homology
 3I0W A;  1YQL A;  2NOZ A;  3I0X A;  1VOL B;  1RM1 A;  3N89 A;  3KRM A;  2NOE A;  1YQR A;  1N3A A;  1M3Q A;  2VJ0 A;  2NOB A;  3RPJ A;  1QN7 A;  4Q11 A;  2O3O A;  3OCI A;  3OC3 C;  3HS8 A;  2HZM A;  2NOI A;  1EBM A;  1N39 A;  1QNA A;  2XHI A;  2FGT A;  1UT4 A;  3H1Z A;  1QNC A;  2G30 A;  2D0A A;  1VOK A;  1QN9 A;  1KO9 A;  2NOL A;  1NVP A;  2I5W A;  1B9K A;  3ASM A;  1PCZ A;  4EJY A;  1W80 A;  4B0A A;  1KY6 A;  1QN5 A;  1KYD A;  3HS9 A;  1C9B B;  1CDW A;  1HU0 A;  4TPS A;  1YTB A;  2HZS A;  3F0Z A;  1KYU A;  3F10 A;  1YTF A;  2NOH A;  4I8O A;  1QTS A;  3DPU A;  1YQM A;  1QN4 A;  1QTP A;  2MZ8 A;  1AIS A;  1LWV A;  3DPT A;  1QN3 A;  4EJZ A;  4WZS D;  5AN4 A;  4ROC B;  1MP9 A;  1LWW A;  1R4X A;  1NGM A;  3IH7 A;  1VTO A;  1VTL E;  1QN6 A;  3OST A;  1TBP A;  1UT7 A;  1PZD A;  2IV9 A;  1JFI C;  1QNB A;  1YQK A;  1KY7 A;  5IYB P;  1QNE A;  2MJ7 A;  2Z8U A;  4DUL A;  2LAE A;  2NOF A;  2JOI A;  3OSM A;  1E42 A;  1D3U A;  1NH2 A;  2YH5 A;  3ULX A;  1LWY A;  3KTU A;  1FN7 A;  3SNS A;  1TBA B;  5IYD P;  1KYF A;  4PY5 A;  1N3C A;  4ROE B;  3EIK A;  2D0B A;  1TGH A;  1QN8 A;  2IV8 A;  5IYC P;  2D0C A;  1M3H A;  3VN5 A;  4ROD B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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