2FKMX

Pmm/pgm s108d mutant with alpha-d-glucose 1,6-bisphosphate bound
Total Genus 170
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
170
sequence length
454
structure length
454
Chain Sequence
PASIFRAYDIRGVVGDTLTAETAYWIGRAIGSESLARGEPCVAVGRDGRLSGPELVKQLIQGLVDCGCQVSDVGMVPTPVLYYAANVLEGKSGVMLTGDHNPPDYNGFKIVVAGETLANEQIQALRERIEKNDLASGVGSVEQVDILPRYFKQIRDDIAMAKPMKVVVDCGNGVAGVIAPQLIEALGCSVIPLYCEVDGNFPNHHPDPGKPENLKDLIAKVKAENADLGLAFDGDGDRVGVVTNTGTIIYPDRLLMLFAKDVVSRNPGADIIFDVKCTRRLIALISGYGGRPVMWKTGHSLIKKKMKETGALLAGEMSGHVFFKERWFGFDDGIYSAARLLEILSQDQRDSEHVFSAFPSDISTPEINITVTEDSKFAIIEALQRDAQWGEGNITTLDGVRVDYPKGWGLVRASNTTPVLVLRFEADTEEELERIKTVFRNQLKAVDSSLPVPF
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule tags Isomerase
molecule keywords Phosphomannomutase/phosphoglucomutase
publication title The reaction of phosphohexomutase from Pseudomonas aeruginosa: structural insights into a simple processive enzyme.
pubmed doi rcsb
source organism Pseudomonas aeruginosa
total genus 170
structure length 454
sequence length 454
ec nomenclature ec 5.4.2.2: Phosphoglucomutase (alpha-D-glucose-1,6-bisphosphate-dependent).
pdb deposition date 2006-01-04

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
X PF00408 PGM_PMM_IV Phosphoglucomutase/phosphomannomutase, C-terminal domain
X PF02878 PGM_PMM_I Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I
X PF02879 PGM_PMM_II Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II
X PF02880 PGM_PMM_III Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.310.50 Alpha Beta 2-Layer Sandwich TATA-Binding Protein Alpha-D-phosphohexomutase, C-terminal domain 2fkmX04
3.40.120.10 Alpha Beta 3-Layer(aba) Sandwich Alpha-D-Glucose-1,6-Bisphosphate; Chain A, domain 3 Alpha-D-Glucose-1,6-Bisphosphate, subunit A, domain 3 2fkmX03
3.40.120.10 Alpha Beta 3-Layer(aba) Sandwich Alpha-D-Glucose-1,6-Bisphosphate; Chain A, domain 3 Alpha-D-Glucose-1,6-Bisphosphate, subunit A, domain 3 2fkmX01
3.40.120.10 Alpha Beta 3-Layer(aba) Sandwich Alpha-D-Glucose-1,6-Bisphosphate; Chain A, domain 3 Alpha-D-Glucose-1,6-Bisphosphate, subunit A, domain 3 2fkmX02
2EIUA 3PDKA 1C4GA 1KFQA 1TUOA 1KFIA 2Z0FA 4MRQA 5EPCA 3UW2A 5BMNA 5JN5A 3PMGA 4QG5A 1JDYA 1P5DX 1WQAA 2DKCA 1P5GX 1WJWA 2DKDA 2FKMX 3I3WA 5HSHA 2FKFA 3RSMA 3OLPA 4IL8A 1VKLA 3C04A 5KL0A 1K35A 5F9CA 2DKAA 2JPIA 3BKQX 5JMVD 1C47A 5BMPA 1LXTA 2F7LA 2H4LX 2H5AX 3ENCA 4BJUA 4HJHA 1PCJX 4WX8A 1K2YX 3NA5A 2EHPA 3ENOC 2FUVA 1PCMX 4WXAA
chains in the Genus database with same CATH superfamily
2HL9A 2LAEA 2NOEA 3SNSA 2QLVA 2ZFDB 2Y8LA 1TGHA 1M5Q1 1KFIA 2EHBD 3CWTA 1KY6A 2OOXA 5BMNA 1YTBA 1YQKA 1YTFA 1JDYA 2QREA 1P5DX 2YH5A 1NH2A 1Q9UA 2MJ7A 1VTLE 1TBAB 4EAJA 2FKMX 3EAYA 3CW7A 4CFFA 2HKPA 2NOHA 1YQRA 2DKAA 3OC3C 3BKQX 2IV8A 4Q11A 4B0AA 1C47A 2OOYA 3OH6A 1W80A 1PZDA 1QNAA 2QRCA 1LWVA 2JOIA 3F10A 3T4NA 4WXAA 2XHIA 4WZSD 3IH7A 1C4GA 3DPTA 3TDHA 1M3QA 3I0XA 1B9KA 2Z0FA 2NLVA 1KO9A 1QTSA 4C7PA 3D7QA 1WQAA 4I8OA 4ROCB 1P5GX 1XSZA 2MZ8A 2I5WA 1NGMA 1QN3A 1UL7A 2G30A 4EAKA 1CDWA 3KTUA 1HU0A 1QN8A 1K35A 4D7RA 1EBMA 2JPIA 2Z8UA 1N3AA 1RM1A 2V8QA 1E42A 4DULA 4EAGA 2JHNA 3CWUA 2NOIA 1K2YX 3I0WA 3ENOC 3CVSA 2Y8QA 1PCMX 1MPGA 3KRMA 4PY5A 3TE5A 2EIUA 2VJ0A 1KFQA 1TBPA 1TUOA 3HS8A 2V92A 3OCIA 4EALA 1QN9A 4MRQA 3HS9A 3UW2A 5JN5A 3PMGA 4QG5A 3D4VA 4EJZA 1AISA 2DKCA 1KYFA 4D7QA 1MP9A 2DKDA 1LWWA 3I3WA 5HSHA 3EIKA 3RSMA 1UT7A 3CVTA 1VKLA 3C04A 5KL0A 1JFIC 1LWYA 1VOLB 5IYBP 2D0AA 2NOFA 1PCZA 1PVSA 1DIZA 3ULXA 3ASMA 3DPUA 5IYDP 5BMPA 1EUVA 1KYDA 1KY7A 3ENCA 2H4LX 3OSMA 5AN4A 2HZSA 1PCJX 4EJYA 3VN5A 2D0CA 1V5SA 1N39A 1QN5A 1QN7A 4EAIA 2FUVA 2NOBA 4ROEB 2PWWA 3RPJA 1QNEA 3PDKA 3CWSA 2QRDA 1N3CA 2JHJA 2YA3A 2NOZA 1YQLA 2IV9A 3F0ZA 1C9BB 1T6AA 5EPCA 1R4XA 2HZMA 5IYCP 2D0BA 3OSEA 1WJWA 3N89A 1D3UA 1VTOA 2FKFA 2R5XA 2NWVA 3OLPA 4IL8A 2NOLA 1QN6A 5F9CA 3CWAA 1M3HA 1QNBA 2NVMA 4TPSA 5JMVD 2FGTA 1FN7A 1QTPA 2HL8A 1NVPA 4RODB 3OH9A 1VOKA 1KYUA 2QR1A 2V9JA 1QN4A 1LXTA 2F7LA 2H5AX 4BJUA 1UT4A 4HJHA 1YQMA 1J3MA 3H1ZA 3NA5A 4WX8A 2O3OA 1QNCA 2EHPA 3OGDA 3OSTA
chains in the Genus database with same CATH topology
2EIUA 3PDKA 1C4GA 1KFQA 1TUOA 1KFIA 2Z0FA 4MRQA 5EPCA 3UW2A 5BMNA 5JN5A 3PMGA 4QG5A 1JDYA 1P5DX 1WQAA 2DKCA 1P5GX 1WJWA 2DKDA 2FKMX 3I3WA 5HSHA 2FKFA 3RSMA 3OLPA 4IL8A 1VKLA 3C04A 5KL0A 1K35A 5F9CA 2DKAA 2JPIA 3BKQX 5JMVD 1C47A 5BMPA 1LXTA 2F7LA 2H4LX 2H5AX 3ENCA 4BJUA 4HJHA 1PCJX 4WX8A 1K2YX 3NA5A 2EHPA 3ENOC 2FUVA 1PCMX 4WXAA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2EIU A;  3PDK A;  1C4G A;  1KFQ A;  1TUO A;  1KFI A;  2Z0F A;  4MRQ A;  5EPC A;  3UW2 A;  5BMN A;  5JN5 A;  3PMG A;  4QG5 A;  1JDY A;  1P5D X;  1WQA A;  2DKC A;  1P5G X;  1WJW A;  2DKD A;  2FKM X;  3I3W A;  5HSH A;  2FKF A;  3RSM A;  3OLP A;  4IL8 A;  1VKL A;  3C04 A;  5KL0 A;  1K35 A;  5F9C A;  2DKA A;  2JPI A;  3BKQ X;  5JMV D;  1C47 A;  5BMP A;  1LXT A;  2F7L A;  2H4L X;  2H5A X;  3ENC A;  4BJU A;  4HJH A;  1PCJ X;  4WX8 A;  1K2Y X;  3NA5 A;  2EHP A;  3ENO C;  2FUV A;  1PCM X;  4WXA A; 
#chains in the Genus database with same CATH topology
 2HL9 A;  2LAE A;  2NOE A;  3SNS A;  2QLV A;  2ZFD B;  2Y8L A;  1TGH A;  1M5Q 1;  1KFI A;  2EHB D;  3CWT A;  1KY6 A;  2OOX A;  5BMN A;  1YTB A;  1YQK A;  1YTF A;  1JDY A;  2QRE A;  1P5D X;  2YH5 A;  1NH2 A;  1Q9U A;  2MJ7 A;  1VTL E;  1TBA B;  4EAJ A;  2FKM X;  3EAY A;  3CW7 A;  4CFF A;  2HKP A;  2NOH A;  1YQR A;  2DKA A;  3OC3 C;  3BKQ X;  2IV8 A;  4Q11 A;  4B0A A;  1C47 A;  2OOY A;  3OH6 A;  1W80 A;  1PZD A;  1QNA A;  2QRC A;  1LWV A;  2JOI A;  3F10 A;  3T4N A;  4WXA A;  2XHI A;  4WZS D;  3IH7 A;  1C4G A;  3DPT A;  3TDH A;  1M3Q A;  3I0X A;  1B9K A;  2Z0F A;  2NLV A;  1KO9 A;  1QTS A;  4C7P A;  3D7Q A;  1WQA A;  4I8O A;  4ROC B;  1P5G X;  1XSZ A;  2MZ8 A;  2I5W A;  1NGM A;  1QN3 A;  1UL7 A;  2G30 A;  4EAK A;  1CDW A;  3KTU A;  1HU0 A;  1QN8 A;  1K35 A;  4D7R A;  1EBM A;  2JPI A;  2Z8U A;  1N3A A;  1RM1 A;  2V8Q A;  1E42 A;  4DUL A;  4EAG A;  2JHN A;  3CWU A;  2NOI A;  1K2Y X;  3I0W A;  3ENO C;  3CVS A;  2Y8Q A;  1PCM X;  1MPG A;  3KRM A;  4PY5 A;  3TE5 A;  2EIU A;  2VJ0 A;  1KFQ A;  1TBP A;  1TUO A;  3HS8 A;  2V92 A;  3OCI A;  4EAL A;  1QN9 A;  4MRQ A;  3HS9 A;  3UW2 A;  5JN5 A;  3PMG A;  4QG5 A;  3D4V A;  4EJZ A;  1AIS A;  2DKC A;  1KYF A;  4D7Q A;  1MP9 A;  2DKD A;  1LWW A;  3I3W A;  5HSH A;  3EIK A;  3RSM A;  1UT7 A;  3CVT A;  1VKL A;  3C04 A;  5KL0 A;  1JFI C;  1LWY A;  1VOL B;  5IYB P;  2D0A A;  2NOF A;  1PCZ A;  1PVS A;  1DIZ A;  3ULX A;  3ASM A;  3DPU A;  5IYD P;  5BMP A;  1EUV A;  1KYD A;  1KY7 A;  3ENC A;  2H4L X;  3OSM A;  5AN4 A;  2HZS A;  1PCJ X;  4EJY A;  3VN5 A;  2D0C A;  1V5S A;  1N39 A;  1QN5 A;  1QN7 A;  4EAI A;  2FUV A;  2NOB A;  4ROE B;  2PWW A;  3RPJ A;  1QNE A;  3PDK A;  3CWS A;  2QRD A;  1N3C A;  2JHJ A;  2YA3 A;  2NOZ A;  1YQL A;  2IV9 A;  3F0Z A;  1C9B B;  1T6A A;  5EPC A;  1R4X A;  2HZM A;  5IYC P;  2D0B A;  3OSE A;  1WJW A;  3N89 A;  1D3U A;  1VTO A;  2FKF A;  2R5X A;  2NWV A;  3OLP A;  4IL8 A;  2NOL A;  1QN6 A;  5F9C A;  3CWA A;  1M3H A;  1QNB A;  2NVM A;  4TPS A;  5JMV D;  2FGT A;  1FN7 A;  1QTP A;  2HL8 A;  1NVP A;  4ROD B;  3OH9 A;  1VOK A;  1KYU A;  2QR1 A;  2V9J A;  1QN4 A;  1LXT A;  2F7L A;  2H5A X;  4BJU A;  1UT4 A;  4HJH A;  1YQM A;  1J3M A;  3H1Z A;  3NA5 A;  4WX8 A;  2O3O A;  1QNC A;  2EHP A;  3OGD A;  3OST A; 
#chains in the Genus database with same CATH homology
 2EIU A;  3PDK A;  1C4G A;  1KFQ A;  1TUO A;  1KFI A;  2Z0F A;  4MRQ A;  5EPC A;  3UW2 A;  5BMN A;  5JN5 A;  3PMG A;  4QG5 A;  1JDY A;  1P5D X;  1WQA A;  2DKC A;  1P5G X;  1WJW A;  2DKD A;  2FKM X;  3I3W A;  5HSH A;  2FKF A;  3RSM A;  3OLP A;  4IL8 A;  1VKL A;  3C04 A;  5KL0 A;  1K35 A;  5F9C A;  2DKA A;  2JPI A;  3BKQ X;  5JMV D;  1C47 A;  5BMP A;  1LXT A;  2F7L A;  2H4L X;  2H5A X;  3ENC A;  4BJU A;  4HJH A;  1PCJ X;  4WX8 A;  1K2Y X;  3NA5 A;  2EHP A;  3ENO C;  2FUV A;  1PCM X;  4WXA A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...